|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
2-320 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 587.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 2 IKKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVA 81
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 82 VREKGIENLKKHGIEALVVIGGDGSYMGAKKLTEMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSH 161
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 162 QRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTELMMDANELAKEIESSTGR 241
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515628560 242 ETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDIIDCIENMQNPDRSELFRVAEELF 320
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKLS 319
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-319 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 516.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAV 82
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 83 REKGIENLKKHGIEALVVIGGDGSYMGAKKLTEMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSHQ 162
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 163 RISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTELMMDANELAKEIESSTGRE 242
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515628560 243 TRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDIIDCIENMQNPDRsELFRVAEEL 319
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMKPFKK-DWLALAKKL 316
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
2-319 |
4.13e-163 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 458.00 E-value: 4.13e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 2 IKKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVA 81
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 82 VREKGIENLKKHGIEALVVIGGDGSYMGAKKLTE-MGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSS 160
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEeYGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 161 HQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTELMMD------------- 227
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAGDedgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 228 ---------ANELAKEIESSTGRETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDII 298
Cdd:COG0205 241 fghvrlggiGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|..
gi 515628560 299 DCIENMQN-PDRSELFRVAEEL 319
Cdd:COG0205 321 EVANKEKPvDPDSPLIQLAREL 342
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-274 |
7.04e-159 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 444.48 E-value: 7.04e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAVR 83
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 84 EKGIENLKKHGIEALVVIGGDGSYMGAKKLT-EMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSHQ 162
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 163 RISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIaKGKKHAIIALTELMMDANELAKEIESSTGRE 242
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 515628560 243 TRATVLGHIQRGGRPTAFDRVLASRMGNYAVH 274
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
4-301 |
2.46e-154 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 434.08 E-value: 2.46e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAVR 83
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 84 EKGIENLKKHGIEALVVIGGDGSYMGAKKLTEMGY-PCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSHQ 162
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEEGGiPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 163 RISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTE--LMMDANELAKEIESSTG 240
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSIIIVAEgnIVGSAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515628560 241 RETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDIIDCI 301
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
2-320 |
0e+00 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 587.05 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 2 IKKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVA 81
Cdd:PRK03202 1 MKRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFPEFKDEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 82 VREKGIENLKKHGIEALVVIGGDGSYMGAKKLTEMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSH 161
Cdd:PRK03202 81 GRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 162 QRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTELMMDANELAKEIESSTGR 241
Cdd:PRK03202 161 ERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKGRERGKKHAIIVVAEGVMPAEELAKEIEERTGL 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515628560 242 ETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDIIDCIENMQNPDRSELFRVAEELF 320
Cdd:PRK03202 241 ETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGIQNNKIVHVPIEEAVENMKHPFDKDLYELAKKLS 319
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-319 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 516.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAV 82
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARFPEFKDEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 83 REKGIENLKKHGIEALVVIGGDGSYMGAKKLTEMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSHQ 162
Cdd:cd00763 81 QAKAIEQLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 163 RISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTELMMDANELAKEIESSTGRE 242
Cdd:cd00763 161 RISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGKKHAIVVVAEGVYDVDELAKEIEEATGFE 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515628560 243 TRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDIIDCIENMQNPDRsELFRVAEEL 319
Cdd:cd00763 241 TRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEQLVHHDIIDAIENMKPFKK-DWLALAKKL 316
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
2-319 |
4.13e-163 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 458.00 E-value: 4.13e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 2 IKKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVA 81
Cdd:COG0205 1 MKRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFKTEE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 82 VREKGIENLKKHGIEALVVIGGDGSYMGAKKLTE-MGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSS 160
Cdd:COG0205 81 GREKALENLKKLGIDALVVIGGDGSLDGAAKLAEeYGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 161 HQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTELMMD------------- 227
Cdd:COG0205 161 HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRKRGKGYSIIVVAEGAGDedgeavleadtda 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 228 ---------ANELAKEIESSTGRETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDII 298
Cdd:COG0205 241 fghvrlggiGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVGIRRGEIVLVPLE 320
|
330 340
....*....|....*....|..
gi 515628560 299 DCIENMQN-PDRSELFRVAEEL 319
Cdd:COG0205 321 EVANKEKPvDPDSPLIQLAREL 342
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
4-274 |
7.04e-159 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 444.48 E-value: 7.04e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAVR 83
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 84 EKGIENLKKHGIEALVVIGGDGSYMGAKKLT-EMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSHQ 162
Cdd:pfam00365 81 EKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 163 RISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIaKGKKHAIIALTELMMDANELAKEIESSTGRE 242
Cdd:pfam00365 161 RVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFSIIVVAEGASDGEFLAKLIEEGTGIE 239
|
250 260 270
....*....|....*....|....*....|..
gi 515628560 243 TRATVLGHIQRGGRPTAFDRVLASRMGNYAVH 274
Cdd:pfam00365 240 TRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
4-301 |
2.46e-154 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 434.08 E-value: 2.46e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAVR 83
Cdd:TIGR02482 1 KIGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRRGYKGLINGKIEPLESKNVSGIIHRGGTILGTARCPEFKTEEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 84 EKGIENLKKHGIEALVVIGGDGSYMGAKKLTEMGY-PCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRDTSSSHQ 162
Cdd:TIGR02482 81 EKAVENLKKLGIEGLVVIGGDGSYTGAQKLYEEGGiPVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 163 RISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTE--LMMDANELAKEIESSTG 240
Cdd:TIGR02482 161 RAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFDYDIDELIQRLKEQHEAGKKHSIIIVAEgnIVGSAKEVAKKIEEKTG 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515628560 241 RETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKEELVHHDIIDCI 301
Cdd:TIGR02482 241 IETRVTVLGHTQRGGSPSAFDRVLASRLGAKAVELLLEGKGGVMIGIQNNKIVTHPIEEAL 301
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-305 |
3.80e-153 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 432.49 E-value: 3.80e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAV 82
Cdd:cd00363 1 KKIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 83 REKGIENLKKHGIEALVVIGGDGSYMGAKKLTEM------GYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRD 156
Cdd:cd00363 81 RAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEwpskyqGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 157 TSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPE---TGLDKEQLISNIQDGIAKGKKHAIIALTELMMDAN---- 229
Cdd:cd00363 161 TASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEepaADEWEEEMVDVIKKRRERGKRHGIVIVAEGAIDFIpkpi 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 230 ---ELAKEIESSTGRETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIEKE---ELVHHDIIDCIEN 303
Cdd:cd00363 241 tekLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGTPVGIQNLnenQVVRHPLTEAVNM 320
|
..
gi 515628560 304 MQ 305
Cdd:cd00363 321 TK 322
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
3-279 |
1.90e-93 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 293.09 E-value: 1.90e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVE--DRIEKLDRSSVSDVINRGGTFLGSARFPEFKDV 80
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIREGYQGLVDggDNIEEAQWEDVRGILSLGGTIIGTARCKEFRER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 81 AVREKGIENLKKHGIEALVVIGGDGSYMGA-----------------KKLTEMGYP------CIGLPGTIDNDIAGTDYT 137
Cdd:TIGR02478 81 PGRLKAARNLVSNGIDALVVIGGDGSLTGAdlfreewpslleelvdtGKITAEQAEehrhltIVGLVGSIDNDMCGTDMT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 138 IGYLTALNTVIDSIDRLRDTSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLD---KEQLISNIQDGIAKGK 214
Cdd:TIGR02478 161 IGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERPPEegwEDQLCHKLKRNRKAGK 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515628560 215 KHAIIALTELMMD-------ANELAKEIESSTGRETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEG 279
Cdd:TIGR02478 241 RKTIVIVAEGAIDrdlnpitSEDVKDVLVERLGLDTRITVLGHVQRGGAPSAFDRILATRQGVEAVLAVLES 312
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
3-279 |
2.16e-82 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 264.38 E-value: 2.16e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVE--DRIEKLDRSSVSDVINRGGTFLGSARFPEFKDV 80
Cdd:cd00764 4 KAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYEGYEGLVKggDYIKQAEWESVSNWLQEGGTIIGSARCKEFRER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 81 AVREKGIENLKKHGIEALVVIGGDGSYMGAK-----------------KLTEMGYP------CIGLPGTIDNDIAGTDYT 137
Cdd:cd00764 84 EGRLQAAYNLIQRGITNLCVIGGDGSLTGADlfrsewpslleelvkdgKITEEEVAkyqhlnIVGMVGSIDNDFCGTDMT 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 138 IGYLTALNTVIDSIDRLRDTSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLD---KEQLISNIQDGIAKGK 214
Cdd:cd00764 164 IGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERPPEdgwEDQMCRRLSEHRSRGK 243
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515628560 215 KHAIIALTELMMDANelAKEIESS---------TGRETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEG 279
Cdd:cd00764 244 RLNIIIVAEGAIDDQ--LKPITSEdvkdlvverLGLDTRVTTLGHVQRGGTPSAFDRILASLMGVEAVMALLEA 315
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
2-308 |
2.07e-72 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 227.65 E-value: 2.07e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 2 IKKIGVLTSGGDAPGMNAAVRGVVRTAL-SVGIEVYGIYDGYQGLVED--RIEKLDRSSVSDVINRGGTFLGSAR----- 73
Cdd:PRK14071 4 KKRIGILTSGGDCAGLNAVIRAVVHRARgTYGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTTNkgdpf 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 74 -FPeFKDVAVREKG---IENLKKHGIEALVVIGGDGSYMGAKKLTEMG-YPCIGLPGTIDNDIAGTDYTIGYLTALNTVI 148
Cdd:PRK14071 84 aFP-MPDGSLRDRSqeiIDGYHSLGLDALIGIGGDGSLAILRRLAQQGgINLVGIPKTIDNDVGATEVSIGFDTAVNIAT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 149 DSIDRLRDTSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAKGKKHAIIALTELMMDA 228
Cdd:PRK14071 163 EALDRLHFTAASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKKIRERQEEGKNFCLVVVSEAVRTE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 229 --------------------NELAKEIESSTGRETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVGIE 288
Cdd:PRK14071 243 egeqvtktqalgedryggigQYLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFDRMVAWQ 322
|
330 340
....*....|....*....|
gi 515628560 289 KEELVHHDIIDCIENMQNPD 308
Cdd:PRK14071 323 NRQVVSVPIAEAIATYRAVD 342
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
3-278 |
1.21e-53 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 186.78 E-value: 1.21e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVAV 82
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELGTNRSLPGDDLGT 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 83 REKGienLKKHGIEALVVIGGDGSYMGAKKL-------TEMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLR 155
Cdd:TIGR02478 470 IAYY---FQQHKIDGLIIIGGFEAFEALYQLdaarekyPAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 156 DTSS-SHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQL---ISNIQDGIAKGKKHAIIALTELMMDA--N 229
Cdd:TIGR02478 547 QSASaSKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLqedIEHLKETFAEGRAGKLILRNEKASKVytT 626
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 515628560 230 ELAKEI--ESSTGR-ETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQE 278
Cdd:TIGR02478 627 DFIARIisEEGKGRfDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIEE 678
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-280 |
2.74e-51 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 180.79 E-value: 2.74e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVavr 83
Cdd:cd00764 391 NIAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELGTKRTLPKKDL--- 467
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 84 EKGIENLKKHGIEALVVIGGDGSYMGAKKL-------TEMGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLRD 156
Cdd:cd00764 468 ETIAYNFQKYGIDGLIIVGGFEAYKGLLQLreareqyEEFCIPMVLIPATVSNNVPGTDFSLGSDTALNALMKYCDRIKQ 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 157 T-SSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQ-------DGIAKGKKHAIIALTElmMDA 228
Cdd:cd00764 548 SaSGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVEhltekmkTTIGRGLVLRNEKCNE--NYT 625
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 515628560 229 NELAKEIESSTGR---ETRATVLGHIQRGGRPTAFDRVLASRMGNYAVHLLQEGH 280
Cdd:cd00764 626 TVFTYELYSEEGKgvfDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKL 680
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
4-287 |
2.14e-38 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 141.33 E-value: 2.14e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTA-LSVGIE-VYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEFKDVA 81
Cdd:PTZ00286 89 KAGIVTCGGLCPGLNVVIRELVMNLiNNYGVKtIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSRGGFDPKVM 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 82 VrekgiENLKKHGIEALVVIGGDGSYMGAKKLTE----MGYPC--IGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLR 155
Cdd:PTZ00286 169 V-----DTLIRHGINILFTLGGDGTHRGALAIYKelrrRKLNIsvVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 156 DTSSSHQR-ISIVEIMGRHCGDLTLMSAIAGGCEYI-ITPETGLDKEQLISNIQDGIAKgKKHAIIALTE---------- 223
Cdd:PTZ00286 244 VEAKSAKNgVGIVKLMGRDSGFIALHASVASADVNVcLIPEFDIPLEGVLEYIEQRLQK-KGHCVIVVAEgagqslkdad 322
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 224 --LMMDA----------NELAKEIESSTGRETRATVLGHIQ-----RGGRPTAFDRVLASRMGNYAVHLLQEGHGGRCVG 286
Cdd:PTZ00286 323 ldLGTDAsgnkklwdigVYLKDEITKYLKKKKPEHTVKYIDpsymiRAVPANAADAKFCTQLAQNAVHGAMAGFTGFIIG 402
|
.
gi 515628560 287 I 287
Cdd:PTZ00286 403 H 403
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
1-291 |
2.94e-31 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 121.12 E-value: 2.94e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 1 MIKKIGVLTSGGDAPGMNAAVRGVVRTALS--VGIEVYGIYDGYQGLVEDRIekLDRSSVSD-----VINRGGTFLGSAR 73
Cdd:PRK14072 2 MKGNALYAQSGGPTAVINASAAGVIEEARKhkKIGKVYGARNGIIGILDEDL--IDLSKESDealaaLAHTPSGALGSCR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 74 F---PEFKDVAVREKGIENLKKHGIEALVVIGGDGSYMGAKKLTE----MGYP--CIGLPGTIDNDIAGTDYTIGYLTA- 143
Cdd:PRK14072 80 YklkSLEEDRAEYERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQlakkMGYPirCIGIPKTIDNDLPGTDHCPGFGSAa 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 144 --LNTVIDSIDrlRDTSSSHQ--RISIVEIMGRHCGDLTLMSAIA-----GGCEYIITPETGLDKEQLISNIQDGIAKgK 214
Cdd:PRK14072 160 kyIATSVLEAA--LDVAAMANtsKVFILEVMGRHAGWLAAAAALAkqnpdDAPHLIYLPERPFDEEKFLADVRAIVKR-Y 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 215 KHAIIALTELMMDAN------------------------ELAKEIESSTGRETRATVLGHIQRGGRPTA--FDRVLASRM 268
Cdd:PRK14072 237 GYCVVVVSEGIRDADgkfiaeaglaedafghaqlggvapVLANLIKEKLGKKVHWAVLDYLQRAARHIAskTDVEEAYAV 316
|
330 340
....*....|....*....|...
gi 515628560 269 GNYAVHLLQEGHGGRCVGIEKEE 291
Cdd:PRK14072 317 GKAAVEYALAGKNGVMPAIRRTS 339
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
4-294 |
2.59e-24 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 102.25 E-value: 2.59e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTALSV-GI-EVYGIYDGYQGLVED---RIEKLDRSSVSDVINRGGTFLGSARFPEFK 78
Cdd:PRK06830 82 KAAIVTCGGLCPGLNDVIRAIVLELHHHyGVrRILGIRYGYQGLIPRyghDPVELTPEVVADIHEFGGTILGSSRGPQDP 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 79 DVAVrekgiENLKKHGIEALVVIGGDGSYMGAKKLTE------MGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSID 152
Cdd:PRK06830 162 EEIV-----DTLERMNINILFVIGGDGTLRGASAIAEeierrgLKISVIGIPKTIDNDINFIQKSFGFETAVEKATEAIR 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 153 rlrdtsSSHQR-------ISIVEIMGRHCGDLTLMSAIAGG-CEYIITPETGLDKEQ---LISNIQDGIAKgKKHAIIAL 221
Cdd:PRK06830 237 ------CAHVEangapngIGLVKLMGRHSGFIAAYAALASKdVNFVLIPEVPFDLEGpngLLAALEKRLAE-RGHAVIVV 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 222 TE-----LM-----MDA--NELAKEIesstGRETRATVLGHIQRGGRP-----------------TAFDRVLASRMGNYA 272
Cdd:PRK06830 310 AEgagqeLFddtgeTDAsgNPKLGDI----GLFLKDRIKEYFKARGIPinlkyidpsyiirsvpaNANDSVYCGFLGQNA 385
|
330 340
....*....|....*....|..
gi 515628560 273 VHLLQEGHGGRCVGIEKEELVH 294
Cdd:PRK06830 386 VHAAMAGKTGMVVGRWNNRFVH 407
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
4-308 |
1.06e-21 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 94.49 E-value: 1.06e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVRTALSVGIE-VYGIYDGYQGLVEDRIEK--LDRSSVSDVINRGGTFLGSARF-PEFKD 79
Cdd:PLN02884 55 KAAIVTCGGLCPGLNDVIRQIVFTLEIYGVKnIVGIPFGYRGFFEKGLSEmpLSRKVVQNIHLSGGSLLGVSRGgAKTSD 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 80 VavrekgIENLKKHGIEALVVIGGDGSYMGAKKLTE------MGYPCIGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDR 153
Cdd:PLN02884 135 I------VDSIEARGINMLFVLGGNGTHAGANAIHNecrkrkMKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRAINS 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 154 LR-DTSSSHQRISIVEIMGRHCGDLTLMSAIAGG-CEYIITPET--GLDKEQLISNIQDGIAKGKKHAIIALTE-----L 224
Cdd:PLN02884 209 AYiEAHSAYHGIGLVKLMGRSSGFIAMHASLASGqVDICLIPEVpfTLDGPNGVLRHLEHLIETKGSAVVCVAEgagqdL 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 225 MMDANEL---AKEIESSTGRETRATVLGHIQRGG-----------------RPTAFDRVLASRMGNYAVHLLQEGHGGRC 284
Cdd:PLN02884 289 LQKTNATdasGNPVLGDIGVHLQQEIKKHFKDIGvpadvkyidptymiracRANASDAILCTVLGQNAVHGAFAGFSGIT 368
|
330 340
....*....|....*....|....
gi 515628560 285 VGIEKEELVHHDIIDCIENMQNPD 308
Cdd:PLN02884 369 VGICNTHYVYLPIPEVIAYPRRVD 392
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
7-184 |
4.36e-20 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 90.19 E-value: 4.36e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 7 VLTSGGDAPGMNAAVRGVVrTALS--VGI-EVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGGTFLGSARFPEfkDVAvr 83
Cdd:PLN02564 92 IVTCGGLCPGLNTVIREIV-CGLSymYGVtRILGIDGGYRGFYSRNTIPLTPKVVNDIHKRGGTILGTSRGGH--DTS-- 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 84 eKGIENLKKHGIEALVVIGGDGSYMGAKKLTE----MGYPC--IGLPGTIDNDIAGTDYTIGYLTALNTVIDSIDRLR-D 156
Cdd:PLN02564 167 -KIVDSIQDRGINQVYIIGGDGTQKGASVIYEeirrRGLKVavAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHvE 245
|
170 180
....*....|....*....|....*...
gi 515628560 157 TSSSHQRISIVEIMGRHCGDLTLMSAIA 184
Cdd:PLN02564 246 AESVENGIGLVKLMGRYSGFIAMYATLA 273
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
3-237 |
1.39e-18 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 86.13 E-value: 1.39e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVRT--ALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGG-TFLGSARfPEFKD 79
Cdd:PRK07085 71 LKVGVILSGGQAPGGHNVIAGLFDGlkKLNPDSKLFGFIGGPLGLLNGKYIEITEEVIDEYRNTGGfDMIGSGR-TKIET 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 80 VAVREKGIENLKKHGIEALVVIGGDGSYMGAKKLTE------MGYPCIGLPGTIDNDIAGT--DYTIGYLTALNT---VI 148
Cdd:PRK07085 150 EEQKEACLETVKKLKLDGLVIIGGDDSNTNAAILAEyfakhgCKTQVIGVPKTIDGDLKNEfiETSFGFDTATKTyseMI 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 149 DSIdrLRDTSSSHQRISIVEIMGR---H----CG-----DLTLMSaiaggcEYIITPETGLDkeQLISNIQDGI----AK 212
Cdd:PRK07085 230 GNI--SRDALSAKKYWHFIKLMGRsasHialeCAlqthpNICLIS------EEVAEKKMSLQ--DIVHYIASVIadraAK 299
|
250 260
....*....|....*....|....*....
gi 515628560 213 GKKHAII----ALTELMMDANELAKEIES 237
Cdd:PRK07085 300 GKNYGVIlipeGLIEFIPEMKSLIKELNS 328
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
1-200 |
7.66e-18 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 83.13 E-value: 7.66e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 1 MIKKIGVLTSGGDAPGMNAAVRGVVR--TALSVGIEVYGIYDGYQGLVE-DRIEKLD--RSSVSDVINRGGTFLGSAR-- 73
Cdd:PRK06555 2 AVKKVALLTAGGLAPCLSSAVGGLIEryTEIAPEVEIIAYRSGYQGLLLgDSIEITPavRANAGLLHRYGGSPIGNSRvk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 74 FPEFKDVAVR---EKG-------IENLKKHGIEALVVIGGDGSYMGA----KKLTEMGYP--CIGLPGTIDNDIAGTDYT 137
Cdd:PRK06555 82 LTNVADCVKRglvKEGenplkvaAERLAADGVDILHTIGGDDTNTTAadlaAYLAENGYDltVVGLPKTIDNDVVPIRQS 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515628560 138 IGYLTALNTVIDSIDRLRDTSSSHQRISIV-EIMGRHCGDLTLMSAIA-----GGCEYIitPETGLDKE 200
Cdd:PRK06555 162 LGAWTAAEQGARFFDNVINEHSANPRMLIIhEVMGRNCGWLTAATARAyrewlDRQEYV--PGFGLSAE 228
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
2-227 |
1.11e-13 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 71.99 E-value: 1.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 2 IKKIGVLTSGGDAPGMNAAVRGVVRTA--LSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGG-TFLGSARFpefk 78
Cdd:PTZ00287 177 VLKIGIILSGGPAPGGHNVISGIYDYAkrYNEQSQVIGFLGGIDGLYSKNYVTITDSLMNRFRNLGGfNMLWSGRG---- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 79 dvAVREK----GIENL-KKHGIEALVVIGGDGSYMGAKKLTE------MGYPCIGLPGTIDNDIA--GTDYTIGYLTALN 145
Cdd:PTZ00287 253 --KVRNKddliAIENIvAKLKLNGLVIIGGDGSNSNAALISEyfaerqIPISIIGIPKTIDGDLKseAIEISFGFDTATK 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 146 TVIDSIDRL-RDTSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETgLDKEQL-----ISNIQDGIAK----GKK 215
Cdd:PTZ00287 331 TYSEVIGNLcTDVKTGHNVYHVVRVMGRSASHVVLECALQTRPNIVLIGEE-VEKENLslkdiVSNIVNTILKrrslNKN 409
|
250
....*....|..
gi 515628560 216 HAIIALTELMMD 227
Cdd:PTZ00287 410 YGVILIPEGLIE 421
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
3-278 |
5.15e-13 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 69.62 E-value: 5.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 3 KKIGVLTSGGDAPGMNAAVRGVVR--TALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGG-TFLGSARFPEFKD 79
Cdd:PTZ00468 103 RRIGVVLSGGQASGGHNVIAGLMSyiKLCNQSSQLFGFLGGPEGVYSERYRELTEDDINGILNQGGfNIICSGRHKIETE 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 80 VAVRE--KGIENLKKHGieaLVVIGGDGSYMGAKKLTEM------GYPCIGLPGTIDNDIAG--TDYTIGYLTALNTVID 149
Cdd:PTZ00468 183 EQMRAslEICEKLKLHG---LVVIGGDDSNTNAAVLAEYfkrnssSTVVVGCPKTIDGDLKNevIETSFGYDTAVKTYSE 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 150 SIDRLRDT-SSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAK--------GKKHAIIA 220
Cdd:PTZ00468 260 QIGSIMDAiKTEGYGYYFVRLMGRSASHITLECGLQTRANMILIGEEIKEENRSLMSIVDEIVEmilkrdslGKKHGIVL 339
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 515628560 221 LTELMMdanELAKEIESSTgRETRATVLGHIQRggrptafdRVLASRMGNYAVHLLQE 278
Cdd:PTZ00468 340 LPEGLI---EFIPEFETLI-KELNLILLKTNDR--------KQIIDSLSQEMKTLFLE 385
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
4-208 |
5.88e-11 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 62.97 E-value: 5.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVV-----RTALSVgieVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGG-TFLGSARfPEF 77
Cdd:cd00765 74 KIGIVLSGGQAPGGHNVISGLFdylkeRAKGST---LYGFKGGPAGILKCDYIELNAEYIQPYRNTGGfDMICSGR-TKI 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 78 KDVAVREKGIENLKKHGIEALVVIGGDGSYMGAKKLTE------MGYPCIGLPGTIDNDIAG--TDYTIGYLTALNTVID 149
Cdd:cd00765 150 ETEDQFKQAEETAKKLDLDALVVIGGDDSNTNAALLAEnfrskgLKTRVIGVPKTIDGDLKNkeIETSFGFDTATKIYSE 229
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 150 SIDRL-RDTSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQD 208
Cdd:cd00765 230 LIGNVmRDARSTGKYWHFVKLMGRSASHIALECALKTHPNICIISEEVSAQKQTLKNITD 289
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
4-227 |
2.50e-09 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 58.27 E-value: 2.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGVVR--TALSVGIEVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGG-TFLGSAR----FPE 76
Cdd:PLN02251 98 KIGVVLSGGQAPGGHNVISGIFDylQEHAKGSVLYGFKGGPAGIMKCKYVELTAEFIYPYRNQGGfDMICSGRdkieTPE 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 77 -FKdvavreKGIENLKKHGIEALVVIGGDGSYMGAKKLTE------MGYPCIGLPGTIDNDIAGTDYTI--GYLTALNTV 147
Cdd:PLN02251 178 qFK------QAEETATKLDLDGLVVIGGDDSNTNACLLAEyfraknLKTRVIGCPKTIDGDLKSKEVPTsfGFDTACKIY 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 148 IDSI-DRLRDTSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPETGLDKEQLISNIQDGIAK--------GKKHAI 218
Cdd:PLN02251 252 SEMIgNVMIDARSTGKYYHFVRLMGRAASHITLECALQTHPNITIIGEEVAAKKLTLKNVTDYIVDvickraelGYNYGV 331
|
....*....
gi 515628560 219 IALTELMMD 227
Cdd:PLN02251 332 ILIPEGLID 340
|
|
| PLN03028 |
PLN03028 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
4-223 |
7.54e-03 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 215543 Cd Length: 610 Bit Score: 37.83 E-value: 7.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 4 KIGVLTSGGDAPGMNAAVRGV-----VRTALSVgieVYGIYDGYQGLVEDRIEKLDRSSVSDVINRGG-TFLGSAR--FP 75
Cdd:PLN03028 81 RVGVVFCGRQSPGGHNVIWGLhdalkAHNPNSV---LLGFLGGTEGLFAQKTLEITDDVLSTYKNQGGyDLLGRTKdqIR 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 76 EFKDVAVREKGIENLKkhgIEALVVIGGDGSYMGAKKLTE--MGYPC----IGLPGTIDNDIAG--TDYTIGYLTA--LN 145
Cdd:PLN03028 158 TTEQVNAALAACEALK---LDGLVIIGGVTSNTDAAQLAEtfAEAKCktkvVGVPVTLNGDLKNqfVETNVGFDTIckVN 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515628560 146 TVIDSiDRLRDTSSSHQRISIVEIMGRHCGDLTLMSAIAGGCEYIITPE----TGLDKEQLISNIQDGI----AKGKKHA 217
Cdd:PLN03028 235 SQLIS-NVCTDALSAEKYYYFIRLMGRKASHVALECALQSHPNMVILGEevaaSKLTLFDITKQICDAVqaraEQDKNHG 313
|
....*.
gi 515628560 218 IIALTE 223
Cdd:PLN03028 314 VILIPE 319
|
|
| |
