|
Name |
Accession |
Description |
Interval |
E-value |
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
1-464 |
9.12e-171 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 488.18 E-value: 9.12e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 1 MARYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVAPRLDGVDYAQPLV 80
Cdd:COG1167 11 GPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAARLPAPAPAPRAA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 81 SEKKAinDRLFDFLksSSAEGVIPFGSAFPDPDLFPLPTLTRNLASAGRKMTGASVINNLPPGSESLRRQIAQRYLQQGI 160
Cdd:COG1167 91 AAVAA--PALRRLL--EAAPGVIDLGSGAPDPDLFPLAALRRALRRALRRLPPALLGYGDPQGLPELREAIARYLARRGV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 161 TVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPiNGLNIEQFENALQNQDVKAC 240
Cdd:COG1167 167 PASPDQILITSGAQQALDLALRALLRPGDTVAVESPTYPGALAALRAAGLRLVPVPVDE-DGLDLDALEAALRRHRPRAV 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 241 WLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLLCGSYSKSLCPGYRVGWV 320
Cdd:COG1167 246 YVTPSHQNPTGATMSLERRRALLELARRHGVPIIEDDYDSELRYDGRPPPPLAALDAPGRVIYIGSFSKTLAPGLRLGYL 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 321 V-NTRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNHLRKLRKNLVVRKERFIDVIKQYFPHSIEIEEPAGGYLIW 399
Cdd:COG1167 326 VaPGRLIERLARLKRATDLGTSPLTQLALAEFLESGHYDRHLRRLRREYRARRDLLLAALARHLPDGLRVTGPPGGLHLW 405
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515632818 400 IRFSEKFDSQQFHQLAIEQGISVASGDLFSEHGRVDNAIRLNFSYELTEEKEQALIWLGKLAHQL 464
Cdd:COG1167 406 LELPEGVDAEALAAAALARGILVAPGSAFSADGPPRNGLRLGFGAPSEEELEEALRRLAELLREL 470
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
103-454 |
1.62e-77 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 245.71 E-value: 1.62e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 103 IPFGSAFPDPDLFPLPTLTRNLASAGRKMTGASvinnLPPGSESLRRQIAQRYLQQ-GITVNHQDIVITSGAMEALNLSL 181
Cdd:cd00609 1 IDLSIGEPDFPPPPEVLEALAAAALRAGLLGYY----PDPGLPELREAIAEWLGRRgGVDVPPEEIVVTNGAQEALSLLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 182 QTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPING-LNIEQFENALQNQDVKACWLmTTFQNPTGTSLSEQAKR 260
Cdd:cd00609 77 RALLNPGDEVLVPDPTYPGYEAAARLAGAEVVPVPLDEEGGfLLDLELLEAAKTPKTKLLYL-NNPNNPTGAVLSEEELE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 261 RVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLLCGSYSKSLC-PGYRVGWVV--NTRFNDAIQKLQLLST 337
Cdd:cd00609 156 ELAELAKKHGILIISDEAYAELVYDGEPPPALALLDAYERVIVLRSFSKTFGlPGLRIGYLIapPEELLERLKKLLPYTT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 338 LSSSAPVQLGVAHFLTHEsyDNHLRKLRKNLVVRKERFIDVIKQYFPhsIEIEEPAGGYLIWIRFSEKFDSQQFHQLAIE 417
Cdd:cd00609 236 SGPSTLSQAAAAAALDDG--EEHLEELRERYRRRRDALLEALKELGP--LVVVKPSGGFFLWLDLPEGDDEEFLERLLLE 311
|
330 340 350
....*....|....*....|....*....|....*..
gi 515632818 418 QGISVASGDLFSEHGrvDNAIRLNFSYeLTEEKEQAL 454
Cdd:cd00609 312 AGVVVRPGSAFGEGG--EGFVRLSFAT-PEEELEEAL 345
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
100-454 |
6.17e-47 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 166.46 E-value: 6.17e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 100 EGVIPFGSAFPDpdlFPLPTLTRNLA--SAGRKMTGASVinnlPPGSESLRRQIAQRYLQ-QGITVNHQDIVITSGAMEA 176
Cdd:COG0436 30 EDVIDLGIGEPD---FPTPDHIREAAieALDDGVTGYTP----SAGIPELREAIAAYYKRrYGVDLDPDEILVTNGAKEA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 177 LNLSLQTVTKSGDNVVIESPAF--YGAlqAVERLGLNPIEVDVCPING--LNIEQFENALqNQDVKACWLmTTFQNPTGT 252
Cdd:COG0436 103 LALALLALLNPGDEVLVPDPGYpsYRA--AVRLAGGKPVPVPLDEENGflPDPEALEAAI-TPRTKAIVL-NSPNNPTGA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 253 SLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDK-TDSVLLCGSYSKSLC-PGYRVGWVV-NTRFNDAI 329
Cdd:COG0436 179 VYSREELEALAELAREHDLLVISDEIYEELVYDGAEHVSILSLPGlKDRTIVINSFSKSYAmTGWRIGYAVgPPELIAAL 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 330 QKLQLLSTLSSSAPVQLGVAHFLTHesYDNHLRKLRKNLVVRKERFIDVIKQyfpHSIEIEEPAGGYLIWIRFSEKF-DS 408
Cdd:COG0436 259 LKLQSNLTSCAPTPAQYAAAAALEG--PQDYVEEMRAEYRRRRDLLVEGLNE---IGLSVVKPEGAFYLFADVPELGlDS 333
|
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 515632818 409 QQF-HQLAIEQGISVASGDLFSEHGrvDNAIRlnFSYELTEEK-EQAL 454
Cdd:COG0436 334 EEFaERLLEEAGVAVVPGSAFGPAG--EGYVR--ISYATSEERlEEAL 377
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
100-450 |
3.93e-25 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 105.85 E-value: 3.93e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 100 EGVIPFGSAfpDPDLFPLPtltrNLASAGRKMTGASVINNLPP--GSESLRRQIAQRYLQQ-GITVNHQD-IVITSGAME 175
Cdd:pfam00155 1 TDKINLGSN--EYLGDTLP----AVAKAEKDALAGGTRNLYGPtdGHPELREALAKFLGRSpVLKLDREAaVVFGSGAGA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 176 ALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPING--LNIEQFENALqnqDVKACWLMTTF-QNPTGT 252
Cdd:pfam00155 75 NIEALIFLLANPGDAILVPAPTYASYIRIARLAGGEVVRYPLYDSNDfhLDFDALEAAL---KEKPKVVLHTSpHNPTGT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 253 SLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAF-DKTDSVLLCGSYSKSL-CPGYRVGWV-VNTRFNDAI 329
Cdd:pfam00155 152 VATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATRALlAEGPNLLVVGSFSKAFgLAGWRVGYIlGNAAVISQL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 330 QKLQLLSTLSSSAPvQLGVAHFLTHESYDNHLRKLRKNLVVRKERFIDVIKQ-YFPHSIeieePAGGYLIWIRFSEKFDS 408
Cdd:pfam00155 232 RKLARPFYSSTHLQ-AAAAAALSDPLLVASELEEMRQRIKERRDYLRDGLQAaGLSVLP----SQAGFFLLTGLDPETAK 306
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 515632818 409 QQFHQLAIEQGISVASGDLFSEHGRvdnaIRLNFSyELTEEK 450
Cdd:pfam00155 307 ELAQVLLEEVGVYVTPGSSPGVPGW----LRITVA-GGTEEE 343
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
100-321 |
1.55e-24 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 104.64 E-value: 1.55e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 100 EGVIPFgsAFPDPDLfPLPTLTRNLASAGRkMTGASVIN-NLppGSESLRRQIAqRYLQQ--GITVNHQDIVITSGAMEA 176
Cdd:PRK06108 24 EGVLPL--WFGESDL-PTPDFIRDAAAAAL-ADGETFYThNL--GIPELREALA-RYVSRlhGVATPPERIAVTSSGVQA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 177 LNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPING---LNIEQFENALqNQDVKACwLMTTFQNPTGTS 253
Cdd:PRK06108 97 LMLAAQALVGPGDEVVAVTPLWPNLVAAPKILGARVVCVPLDFGGGgwtLDLDRLLAAI-TPRTRAL-FINSPNNPTGWT 174
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515632818 254 LSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKP--LKAFDKTDSVLLCGSYSKSLC-PGYRVGWVV 321
Cdd:PRK06108 175 ASRDDLRAILAHCRRHGLWIVADEVYERLYYAPGGRAPsfLDIAEPDDRIIFVNSFSKNWAmTGWRLGWLV 245
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
64-450 |
2.09e-24 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 104.57 E-value: 2.09e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 64 YFVAPRLdgvdyaqpLVSEKKAINDrLFDflKSSSAEGVIPFGSAFPDpdlFPLPtltRNLASAGRKMTGASVINNLP-P 142
Cdd:PRK08361 8 YFIAGRI--------NLIQRSKIRE-LFE--RASKMENVISLGIGEPD---FDTP---KNIKEAAKRALDEGWTHYTPnA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQRYLQ-QGITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPIN 221
Cdd:PRK08361 71 GIPELREAIAEYYKKfYGVDVDVDNVIVTAGAYEATYLAFESLLEEGDEVIIPDPAFVCYVEDAKIAEAKPIRIPLREEN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 222 GLNIEQFEnALQNQDVKACWLMTTF-QNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFdKTDS 300
Cdd:PRK08361 151 EFQPDPDE-LLELITKRTRMIVINYpNNPTGATLDKEVAKAIADIAEDYNIYILSDEPYEHFLYEGAKHYPMIKY-APDN 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 301 VLLCGSYSKSLC-PGYRVGWVVN-TRFNDAIQKLQLLSTLSSSAPVQL-GVAHFLTHESYDNhLRKLRKNLVVRKERFID 377
Cdd:PRK08361 229 TILANSFSKTFAmTGWRLGFVIApEQVIKDMIKLHAYIIGNVASFVQIaGIEALRSKESWKA-VEEMRKEYNERRKLVLK 307
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515632818 378 VIKQyFPHsIEIEEPAGGYLIWIRFSE-KFDSQQFHQLAIEQ-GISVASGDLFSEHGrvDNAIRLnfSYELTEEK 450
Cdd:PRK08361 308 RLKE-MPH-IKVFEPKGAFYVFANIDEtGMSSEDFAEWLLEKaRVVVIPGTAFGKAG--EGYIRI--SYATSKEK 376
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
99-321 |
1.80e-22 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 98.66 E-value: 1.80e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 99 AEG--VIPFGSAFPDpdlFPLPTLTRNLA--SAGRKMTGASVINNLPPgsesLRRQIAQRYLQQ-GITVNHQDIVITSGA 173
Cdd:PRK05764 28 AQGrdVISLGAGEPD---FDTPEHIKEAAieALDDGKTKYTPAAGIPE----LREAIAAKLKRDnGLDYDPSQVIVTTGA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 174 MEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPING--LNIEQFENALqNQDVKacWLMTTF-QNPT 250
Cdd:PRK05764 101 KQALYNAFMALLDPGDEVIIPAPYWVSYPEMVKLAGGVPVFVPTGEENGfkLTVEQLEAAI-TPKTK--ALILNSpSNPT 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515632818 251 GTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPL-----KAFDKTdsvLLCGSYSKSLC-PGYRVGWVV 321
Cdd:PRK05764 178 GAVYSPEELEAIADVAVEHDIWVLSDEIYEKLVYDGAEFTSIaslspELRDRT---ITVNGFSKAYAmTGWRLGYAA 251
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
142-328 |
6.95e-22 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 97.19 E-value: 6.95e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 142 PGSESLRRQIAqRYL--QQGITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAF--YGALqaVERLGLNPIEVDV 217
Cdd:PRK06836 73 AGYPEVREAIA-ESLnrRFGTPLTADHIVMTCGAAGALNVALKAILNPGDEVIVFAPYFveYRFY--VDNHGGKLVVVPT 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 218 CPIN-GLNIEQFENALqNQDVKACwLMTTFQNPTGTSLSEQAKRRVVEI----AEQHGT--YIIEDDVYGDLYYEGHK-P 289
Cdd:PRK06836 150 DTDTfQPDLDALEAAI-TPKTKAV-IINSPNNPTGVVYSEETLKALAALleekSKEYGRpiYLISDEPYREIVYDGAEvP 227
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 515632818 290 KPLKAFDKTdsvLLCGSYSKSLC-PGYRVGWV-VNTRFNDA 328
Cdd:PRK06836 228 YIFKYYDNS---IVVYSFSKSLSlPGERIGYIaVNPEMEDA 265
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
142-321 |
3.29e-21 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 95.10 E-value: 3.29e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 142 PGSESLRRQIAQRYLQQ---GITVNhqDIVITSGAMEALNLSLQTVTKSGDNVVIESPAF--YGALQAVERLGLNPIevD 216
Cdd:TIGR01265 73 VGALAAREAVAEYLSSDlpgKLTAD--DVVLTSGCSQAIEICIEALANPGANILVPRPGFplYDTRAAFSGLEVRLY--D 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 217 VCPING--LNIEQFENALQnqDVKACWLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKA 294
Cdd:TIGR01265 149 LLPEKDweIDLDGLESLAD--EKTVAIVVINPSNPCGSVFSRDHLQKIAEVAEKLGIPIIADEIYGHMVFGDAPFIPMAS 226
|
170 180
....*....|....*....|....*...
gi 515632818 295 FDKTDSVLLCGSYSKS-LCPGYRVGWVV 321
Cdd:TIGR01265 227 FASIVPVLSLGGISKRwVVPGWRLGWII 254
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
141-330 |
7.16e-21 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 94.02 E-value: 7.16e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 141 PPGSESLRRQIAQRYLQQ-GITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCP 219
Cdd:PRK06348 65 SGGDVELIEEIIKYYSKNyDLSFKRNEIMATVGACHGMYLALQSILDPGDEVIIHEPYFTPYKDQIEMVGGKPIILETYE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 220 ING--LNIEQFENALQNQdVKACwLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEgHKPKPLKAFDK 297
Cdd:PRK06348 145 EDGfqINVKKLEALITSK-TKAI-ILNSPNNPTGAVFSKETLEEIAKIAIEYDLFIISDEVYDGFSFY-EDFVPMATLAG 221
|
170 180 190
....*....|....*....|....*....|....*.
gi 515632818 298 T-DSVLLCGSYSKSLC-PGYRVGWVVNTRF-NDAIQ 330
Cdd:PRK06348 222 MpERTITFGSFSKDFAmTGWRIGYVIAPDYiIETAK 257
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
110-321 |
2.45e-20 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 92.54 E-value: 2.45e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 110 PDPDLFPL----PTLTRNL---ASAGRKMTGA---SVINNLPP--GSESLRRQIAQRYLQQGITVNHQDIVITSGAMEAL 177
Cdd:TIGR01264 29 PEKPMIKLsigdPTVFGNLptdPEVMQAMKDSldsGKYNGYAPtvGALSAREAIASYYHNPDGPIEADDVVLCSGCSHAI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 178 NLSLQTVTKSGDNVVIESPAF--YGALqaVERLGLNPIEVDVCPINGLNIEQFENALQNQDVKACWLMTTFQNPTGTSLS 255
Cdd:TIGR01264 109 EMCIAALANAGQNILVPRPGFplYETL--AESMGIEVKLYNLLPDKSWEIDLKQLESLIDEKTAALIVNNPSNPCGSVFS 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515632818 256 EQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLLCGSYSKS-LCPGYRVGWVV 321
Cdd:TIGR01264 187 RQHLEEILAVAERQCLPIIADEIYGDMVFSGATFEPLASLSSTVPILSCGGLAKRwLVPGWRLGWII 253
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
143-331 |
3.96e-20 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 91.84 E-value: 3.96e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQRYLQQGITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESP------AFYGALQAVerlgLNPIEVD 216
Cdd:PRK07568 67 GIPELREAFAKYYKKWGIDVEPDEILITNGGSEAILFAMMAICDPGDEILVPEPfyanynGFATSAGVK----IVPVTTK 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 217 vcPINGL---NIEQFENALqNQDVKACwLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLK 293
Cdd:PRK07568 143 --IEEGFhlpSKEEIEKLI-TPKTKAI-LISNPGNPTGVVYTKEELEMLAEIAKKHDLFLISDEVYREFVYDGLKYTSAL 218
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 515632818 294 AF-DKTDSVLLCGSYSK--SLCpGYRVGWVV--NTRFNDAIQK 331
Cdd:PRK07568 219 SLeGLEDRVIIIDSVSKrySAC-GARIGCLIskNKELIAAAMK 260
|
|
| PRK15481 |
PRK15481 |
transcriptional regulatory protein PtsJ; Provisional |
5-429 |
6.57e-20 |
|
transcriptional regulatory protein PtsJ; Provisional
Pssm-ID: 185378 [Multi-domain] Cd Length: 431 Bit Score: 91.65 E-value: 6.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 5 EELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFV-----APRLDGVDYAQPL 79
Cdd:PRK15481 8 NEIFDSIRQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIrgspsPVALEGGDPGTPL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 80 vsekkaindrlfdflksssaegvIPFGSAFPDPDLfpLPTLTRNLASAGRK--MTGASVINnlpPGSESLrrqiAQRYLQ 157
Cdd:PRK15481 88 -----------------------HDLAGGNPDPQR--LPDLSRYFARLSRTprLYGDAPVS---PELHAW----AARWLR 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 158 QGITVNHqDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVcPINGLNIEQFENALqNQDV 237
Cdd:PRK15481 136 DDCPVAF-EIDLTSGAIDAIERLLCAHLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSV-DAEGMQPEKLERAL-AQGA 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 238 KACWLMTTFQNPTGTSLSEQAKRRVVEIAEQH-GTYIIEDDVYGDL----YyegHKPKPLkafdKTDSVLLCGSYSKSLC 312
Cdd:PRK15481 213 RAVILTPRAHNPTGCSLSARRAAALRNLLARYpQVLVIIDDHFALLssspY---HSVIPQ----TTQRWALIRSVSKALG 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 313 PGYRVGWV---------VNTRFNDAIQklqllstlsssapvqlGVAHFL--------THESYDNHLRKLRKNLVVRKERF 375
Cdd:PRK15481 286 PDLRLAFVasdsatsarLRLRLNSGTQ----------------WVSHLLqdlvyaclTDPEYQARLAQARLFYAQRRQKL 349
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 515632818 376 IDVIKQyfpHSIEIEEPAGGYLIWIRFSEKFDSQQFhQLAiEQGISVASGDLFS 429
Cdd:PRK15481 350 ARALQQ---YGIAIPSPGDGLNLWLPLDTDSQATAL-TLA-KSGWLVREGEAFG 398
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
89-465 |
3.32e-19 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 89.02 E-value: 3.32e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 89 RLFDFlkSSSAEGVIPFGSAFPDpdlFPLPTLTR--NLASAGRKMTGASVinnlPPGSESLRRQIAqRYLQQGITVNH-- 164
Cdd:PRK07682 11 KFFDL--AANMEGVISLGVGEPD---FVTPWNVReaSIRSLEQGYTSYTA----NAGLLELRQEIA-KYLKKRFAVSYdp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 165 -QDIVITSGAMEALNLSLQTVTKSGDNVVIESPAF--YGALqaVERLGLNPIEVDVCPING--LNIEQFENALQNQdVKA 239
Cdd:PRK07682 81 nDEIIVTVGASQALDVAMRAIINPGDEVLIVEPSFvsYAPL--VTLAGGVPVPVATTLENEfkVQPAQIEAAITAK-TKA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 240 CwLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEG-HKPKPLKAFDKTDSVLLCGsYSKSLC-PGYRV 317
Cdd:PRK07682 158 I-LLCSPNNPTGAVLNKSELEEIAVIVEKHDLIVLSDEIYAELTYDEaYTSFASIKGMRERTILISG-FSKGFAmTGWRL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 318 GWVVN-TRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNHlrKLRKNLVVRKERFIDVIKQYfphSIEIEEPAGGY 396
Cdd:PRK07682 236 GFIAApVYFSEAMLKIHQYSMMCAPTMAQFAALEALRAGNDDVI--RMRDSYRKRRNFFVTSFNEI---GLTCHVPGGAF 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515632818 397 LIW--IRfSEKFDSQQF-HQLAIEQGISVASGDLFSEHGrvDNAIRLNFSYELtEEKEQALIWLGKLAHQLT 465
Cdd:PRK07682 311 YAFpsIS-STGLSSEEFaEQLLLEEKVAVVPGSVFGESG--EGFIRCSYATSL-EQLQEAMKRMKRFVENKK 378
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
149-451 |
4.25e-19 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 88.63 E-value: 4.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 149 RQIAQRYLQQGITVNH---QDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPIN-GLN 224
Cdd:PRK07683 71 RKAACNFVKDKYDLHYspeSEIIVTIGASEAIDIAFRTILEPGTEVILPAPIYPGYEPIIRLCGAKPVFIDTRSTGfRLT 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 225 IEQFENALQnqDVKACWLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLLC 304
Cdd:PRK07683 151 AEALENAIT--EKTRCVVLPYPSNPTGVTLSKEELQDIADVLKDKNIFVLSDEIYSELVYEQPHTSIAHFPEMREKTIVI 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 305 GSYSKSLC-PGYRVGWVVNTRF-NDAIQKLQLLSTLSSSAPVQLGVAHFLTheSYDNHLRKLRKNLvvrKERFIDVIKQY 382
Cdd:PRK07683 229 NGLSKSHSmTGWRIGFLFAPSYlAKHILKVHQYNVTCASSISQYAALEALT--AGKDDAKMMRHQY---KKRRDYVYNRL 303
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515632818 383 FPHSIEIEEPAGGYLIWIRFSeKFDSQQFH---QLAIEQGISVASGDLFSEHGrvDNAIRLNFSYELTEEKE 451
Cdd:PRK07683 304 ISMGLDVEKPTGAFYLFPSIG-HFTMSSFDfalDLVEEAGLAVVPGSAFSEYG--EGYVRLSYAYSIETLKE 372
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
3-67 |
4.50e-18 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 77.87 E-value: 4.50e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515632818 3 RYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVA 67
Cdd:cd07377 2 LYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
101-398 |
7.22e-18 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 85.09 E-value: 7.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 101 GVIPFGSAFPDPDLFPlptltRNLASAGRKMTGAsvINNLPPG--SESLRRQIA-QRYLQQGITVN-HQDIVITSGAMEA 176
Cdd:PRK07777 25 GAVNLGQGFPDEDGPP-----EMLEAAQEAIAGG--VNQYPPGpgIPELRAAIAaQRRRRYGLEYDpDTEVLVTVGATEA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 177 LNLSLQTVTKSGDNVVIESPaFYGALQAVERL-GLNPIEVDVCPING---LNIEQFENALQNQdVKACwLMTTFQNPTGT 252
Cdd:PRK07777 98 IAAAVLGLVEPGDEVLLIEP-YYDSYAAVIAMaGAHRVPVPLVPDGRgfaLDLDALRAAVTPR-TRAL-IVNSPHNPTGT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 253 SLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAF----DKTDSVllcGSYSKSL-CPGYRVGWVVNTR-FN 326
Cdd:PRK07777 175 VLTAAELAAIAELAVEHDLLVITDEVYEHLVFDGARHLPLATLpgmrERTVTI---SSAAKTFnVTGWKIGWACGPApLI 251
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515632818 327 DAIQKLQLLSTLSSSAPVQLGVAHFLTHEsyDNHLRKLRKNLVVRKERFIDVIKQYfphSIEIEEPAGGYLI 398
Cdd:PRK07777 252 AAVRAAKQYLTYVGGAPFQPAVAHALDHE--DAWVAALRDSLQAKRDRLAAGLAEA---GFEVHDSAGTYFL 318
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
102-331 |
1.15e-16 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 81.74 E-value: 1.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 102 VIPFGSAfpDPDLFPL----PTLTRNLASAGRkmTGASVINNLPPGSESLRRQIAQrYLQQGI--TVNHQDIVITSGAME 175
Cdd:PLN00145 54 VLPLGHG--DPSAFPCfrtaPEAEDAVAAALR--SGKYNSYSTCVGLLPARRAIAE-YLSRDLpyELSTDDIYLTAGCAQ 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 176 ALNLSLQTVTKSGDNVVIESPAF--YGAlqaveRLGLNPIEV---DVCPING--LNIEQFEnALQNQDVKACwLMTTFQN 248
Cdd:PLN00145 129 AIEIIMSVLAQPGANILLPRPGYplYEA-----RAVFSGLEVrhfDLLPERGweVDLEGVE-ALADENTVAM-VIINPNN 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 249 PTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYeGHKP-KPLKAFDKTDSVLLCGSYSKS-LCPGYRVGWVVNTRFN 326
Cdd:PLN00145 202 PCGSVYSYEHLAKIAETARKLGILVIADEVYDHLTF-GSKPfVPMGVFGEVAPVLTLGSISKRwVVPGWRLGWIATCDPN 280
|
....*
gi 515632818 327 DAIQK 331
Cdd:PLN00145 281 GILKE 285
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
130-323 |
1.48e-16 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 81.51 E-value: 1.48e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 130 KMTGASVINNLPpgseSLRRQIAQrYLQQGI--TVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAF--YgALQAV 205
Cdd:PLN02656 65 KFNGYAPTVGLP----QARRAIAE-YLSRDLpyKLSLDDVFITSGCTQAIDVALSMLARPGANILLPRPGFpiY-ELCAA 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 206 ERlGLNPIEVDVCPINGLNIE-QFENALQNQDVKACWLMTTfQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYY 284
Cdd:PLN02656 139 FR-HLEVRYVDLLPEKGWEVDlDAVEALADQNTVALVIINP-GNPCGNVYSYQHLKKIAETAEKLKILVIADEVYGHLAF 216
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 515632818 285 EGHKPKPLKAFDKTDSVLLCGSYSKS-LCPGYRVGWVVNT 323
Cdd:PLN02656 217 GSNPFVPMGVFGSIVPVLTLGSLSKRwIVPGWRLGWFVTT 256
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
149-451 |
6.78e-16 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 79.00 E-value: 6.78e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 149 RQIAQRYLQQGITVNHQ---DIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPIN-GLN 224
Cdd:PRK07309 73 RQAAADFVKEKYNLDYApenEILVTIGATEALSASLTAILEPGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENDfVLT 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 225 IEQFENAL--QNQDVKACwLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVL 302
Cdd:PRK07309 153 PEMLEKAIleQGDKLKAV-ILNYPANPTGVTYSREQIKALADVLKKYDIFVISDEVYSELTYTGEPHVSIAEYLPDQTIL 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 303 LCGsYSKS-LCPGYRVGWVVNTR-FNDAIQKLQLLSTLSSSAPVQLGVAHFLTHESYDNhlRKLRKNLVVRKERFIDVIK 380
Cdd:PRK07309 232 ING-LSKShAMTGWRIGLIFAPAeFTAQLIKSHQYLVTAATTMAQFAAVEALTNGKDDA--LPMKKEYIKRRDYIIEKMT 308
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515632818 381 QYfphSIEIEEPAGGYLIWIRFSEKF--DSQQFHQ-LAIEQGISVASGDLFSEHGrvDNAIRLNFSYELTEEKE 451
Cdd:PRK07309 309 DL---GFKIIKPDGAFYIFAKIPAGYnqDSFKFLQdFARKKAVAFIPGAAFGPYG--EGYVRLSYAASMETIKE 377
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
112-443 |
2.17e-15 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 77.69 E-value: 2.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 112 PDLFPLPTLTRNLASAGRK--MTGASVINNLPPGSESLRRQIAQRYlqqGITVNHQDIVITSGAMEALNLSLQTVTKSGD 189
Cdd:PRK07550 39 PGYPPPPELLRALAEAAADpaAHLYGPVEGLPELREAYAAHYSRLY---GAAISPEQVHITSGCNQAFWAAMVTLAGAGD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 190 NVVIESPAFYGALQAVERLGLNPIEVDVCPINGL--NIEQFENALQNQdVKACWLMTTfQNPTGTSLSEQAKRRVVEIAE 267
Cdd:PRK07550 116 EVILPLPWYFNHKMWLDMLGIRPVYLPCDEGPGLlpDPAAAEALITPR-TRAIALVTP-NNPTGVVYPPELLHELYDLAR 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 268 QHGTYIIEDDVYGDLYYEGHKPKPLKAF-DKTDSVLLCGSYSKSLC-PGYRVGWVVN--------TRFNDAIQklqllst 337
Cdd:PRK07550 194 RHGIALILDETYRDFDSGGGAPHDLFADpDWDDTLVHLYSFSKSYAlTGHRVGAVVAspariaeiEKFMDTVA------- 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 338 lsSSAP--VQLGVAHFLTHesYDNHLRKLRKNLVVRKERFIDVIKQyfPHSIEIEEpAGGYLIWIR--FSEKFDSQQFHQ 413
Cdd:PRK07550 267 --ICAPriGQIAVAWGLPN--LADWRAGNRAEIARRRDAFRAVFAR--LPGWELLA-SGAYFAYVRhpFPDRPSREVARR 339
|
330 340 350
....*....|....*....|....*....|
gi 515632818 414 LAIEQGISVASGDLFSEHGrvDNAIRLNFS 443
Cdd:PRK07550 340 LAKEAGILCLPGTMFGPGQ--EGYLRLAFA 367
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
111-321 |
5.23e-15 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 76.25 E-value: 5.23e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 111 DPDLFPLPTLTRNLASAGRKmtGASVINNlPPGSESLRRQIAQRYLQQ-GITVNHQDIVITSGAMEALNLSLQTVTKSGD 189
Cdd:PRK07337 39 EPDFTAPEPVVEAAARALRR--GVTQYTS-ALGLAPLREAIAAWYARRfGLDVAPERIVVTAGASAALLLACLALVERGD 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 190 NVVIESPAFYGALQAVERLGLNPIEVDVCPInglniEQFEnaLQNQDVKACW-------LMTTFQNPTGTSLSEQAKRRV 262
Cdd:PRK07337 116 EVLMPDPSYPCNRHFVAAAEGRPVLVPSGPA-----ERFQ--LTAADVEAAWgertrgvLLASPSNPTGTSIAPDELRRI 188
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 263 VEIAEQHGTYIIEDDVYGDLYYEGHkpkPLKAFDKTDSVLLCGSYSKSL-CPGYRVGWVV 321
Cdd:PRK07337 189 VEAVRARGGFTIVDEIYQGLSYDAA---PVSALSLGDDVITINSFSKYFnMTGWRLGWLV 245
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
95-321 |
5.54e-15 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 76.36 E-value: 5.54e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 95 KSSSAEGVIPFGSAFP--DPDLFPLPTLTRNLASAGRkmtgASVINNLPP--GSESLRRQIAQRYL-------QQGITVN 163
Cdd:PTZ00433 28 PSPSPKSIIKLSVGDPtlDGNLLTPAIQTKALVEAVD----SQECNGYPPtvGSPEAREAVATYWRnsfvhkeSLKSTIK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 164 HQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLG-------LNP---IEVDVCPINGLnieqfenalQ 233
Cdd:PTZ00433 104 KDNVVLCSGVSHAILMALTALCDEGDNILVPAPGFPHYETVCKAYGiemrfynCRPekdWEADLDEIRRL---------V 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 234 NQDVKAcWLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLLCGSYSKSL-C 312
Cdd:PTZ00433 175 DDRTKA-LIMTNPSNPCGSNFSRKHVEDIIRLCEELRLPLISDEIYAGMVFNGATFTSVADFDTTVPRVILGGTAKNLvV 253
|
....*....
gi 515632818 313 PGYRVGWVV 321
Cdd:PTZ00433 254 PGWRLGWLL 262
|
|
| YhcF |
COG1725 |
DNA-binding transcriptional regulator YhcF, GntR family [Transcription]; |
4-102 |
1.49e-14 |
|
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
Pssm-ID: 441331 [Multi-domain] Cd Length: 114 Bit Score: 69.82 E-value: 1.49e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 4 YEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVAPRLDGVDYAQplvsEK 83
Cdd:COG1725 12 YEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARELLEER----RE 87
|
90
....*....|....*....
gi 515632818 84 KAINDRLFDFLKSSSAEGV 102
Cdd:COG1725 88 EFLEEALRELVAEARRLGL 106
|
|
| MngR |
COG2188 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
1-69 |
3.33e-14 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441791 [Multi-domain] Cd Length: 238 Bit Score: 71.82 E-value: 3.33e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515632818 1 MARYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVAPR 69
Cdd:COG2188 4 VPLYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAEP 72
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
143-321 |
4.54e-14 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 73.43 E-value: 4.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQRYLQqgitVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAfYGALQAV-ERLGlnpIEVDVCPI- 220
Cdd:PRK07324 63 GSPEFKEAVASLYQN----VKPENILQTNGATGANFLVLYALVEPGDHVISVYPT-YQQLYDIpESLG---AEVDYWQLk 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 221 --NGL--NIEQFENaLQNQDVKacwlMTTFQN---PTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLK 293
Cdd:PRK07324 135 eeNGWlpDLDELRR-LVRPNTK----LICINNannPTGALMDRAYLEEIVEIARSVDAYVLSDEVYRPLDEDGSTPSIAD 209
|
170 180 190
....*....|....*....|....*....|
gi 515632818 294 AFDKTDSVllcGSYSK--SLcPGYRVGWVV 321
Cdd:PRK07324 210 LYEKGIST---NSMSKtySL-PGIRVGWIA 235
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
143-433 |
1.10e-13 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 72.53 E-value: 1.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQR-YLQQGITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPIN 221
Cdd:PRK08363 71 GLPELREAIVKReKRKNGVDITPDDVRVTAAVTEALQLIFGALLDPGDEILIPGPSYPPYTGLVKFYGGVPVEYRTIEEE 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 222 GL--NIEQFENALQNQDVKACwlMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGhKPKPLKAFDKTD 299
Cdd:PRK08363 151 GWqpDIDDIRKKITEKTKAIA--VINPNNPTGALYEKKTLKEILDIAGEHDLPVISDEIYDLMTYEG-KHVSPGSLTKDV 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 300 SVLLCGSYSKS-LCPGYRVGWV--VN-----TRFNDAIQKLQLLSTLSSSaPVQLGVAHFLT--HESYDNHLRKL--RKN 367
Cdd:PRK08363 228 PVIVMNGLSKVyFATGWRLGYIyfVDpegklAEVREAIDKLARIRLCPNT-PAQFAAIAGLTgpMDYLEEYMKKLkeRRD 306
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515632818 368 LVVRKERFIDvikqyfphSIEIEEPAGGYLIWIRFSE---KFDSQQFHQLAIEQGISVASGDLFSEHGR 433
Cdd:PRK08363 307 YIYKRLNEIP--------GISTTKPQGAFYIFPRIEEgpwKDDKEFVLDVLHEAHVLFVHGSGFGEYGA 367
|
|
| PRK08636 |
PRK08636 |
LL-diaminopimelate aminotransferase; |
166-432 |
1.44e-13 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 236316 Cd Length: 403 Bit Score: 72.04 E-value: 1.44e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 166 DIVITSGAMEALNLSLQTVTKSGDNVVIESP-------AFYGALQAVERLGLN---PIEVDVcpiNGLnIEQFENALQNQ 235
Cdd:PRK08636 97 EVVATMGSKEGYVHLVQAITNPGDVAIVPDPaypihsqAFILAGGNVHKMPLEyneDFELDE---DQF-FENLEKALRES 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 236 DVKACWLMTTF-QNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHK-PKPLKAFDKTDSVLLCGSYSKSL-C 312
Cdd:PRK08636 173 SPKPKYVVVNFpHNPTTATVEKSFYERLVALAKKERFYIISDIAYADITFDGYKtPSILEVEGAKDVAVESYTLSKSYnM 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 313 PGYRVGWVV-NTRFNDAIQKLQLLSTLSSSAPVQlgVAHFLTHESYDNHLRKLRKnlVVRKERfiDVIKQYFPHS-IEIE 390
Cdd:PRK08636 253 AGWRVGFVVgNKKLVGALKKIKSWLDYGMFTPIQ--VAATIALDGDQSCVEEIRE--TYRKRR--DVLIESFANAgWELQ 326
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 515632818 391 EPAGGYLIWIRFSEKF---DSQQF-HQLAIEQGISVASGDLFSEHG 432
Cdd:PRK08636 327 KPRASMFVWAKIPEPArhlGSLEFsKQLLTEAKVAVSPGIGFGEYG 372
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
93-445 |
8.09e-13 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 70.04 E-value: 8.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 93 FLKSSSAEG----VIPFGsaFPDPDLFPLPTLTRNLASAGRKMTGASVINNLPP--GSESLRRQIAQrYLQQGI--TVNH 164
Cdd:PLN00143 21 FLKENFNEDdhrlAISFG--FGDPSCFECFRTTNIAEDAIVEAVRSAKFNSYAPtgGILPARRAIAD-YLSNDLpyQLSP 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 165 QDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPING--LNIEQFEnALQNQDVKACWL 242
Cdd:PLN00143 98 DDVYLTLGCKHAAEIIIKVLARPEANILLPRPGFPDVETYAIFHHLEIRHFDLLPEKGweVDLDAVE-AIADENTIAMVI 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 243 MTTfQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYeGHKP-KPLKAFDKTDSVLLCGSYSKS-LCPGYRVGWV 320
Cdd:PLN00143 177 INP-GNPCGSVYSYEHLNKIAETARKLGILVIADEVYGHIVF-GSKPfVPMGLFASIVPVITLGSISKRwMIPGWGLGWL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 321 VNTRFNDAIQK---LQLLSTLSSSAP-----VQLGVAHFL---THESYDNHLRKLRKNLVVRKERFIDVIKQYFPhsiei 389
Cdd:PLN00143 255 VTCDPSGLLQIceiADSIKKALNPAPfpptfIQAAIPEILektTEDFFSKTINILRAALAFCYDKLKEIPCIMCP----- 329
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515632818 390 EEPAGGYLIWIRFSEKF-----DSQQF-HQLAIEQGISVASGDLFSehgrVDNAIRLNFSYE 445
Cdd:PLN00143 330 QKAEGAFFALVKLNLLLledieDDMEFcLKLAKEESLIILPGVTVG----LKNWLRITFAVE 387
|
|
| HTH_GNTR |
smart00345 |
helix_turn_helix gluconate operon transcriptional repressor; |
7-66 |
1.57e-12 |
|
helix_turn_helix gluconate operon transcriptional repressor;
Pssm-ID: 197669 [Multi-domain] Cd Length: 60 Bit Score: 62.21 E-value: 1.57e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 7 LAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFV 66
Cdd:smart00345 1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
143-321 |
2.52e-12 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 68.16 E-value: 2.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQRYLQQ-GITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPin 221
Cdd:PRK08960 70 GLPALREAIAGFYAQRyGVDVDPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGP-- 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 222 glnieqfENALQ--NQDVKACW-------LMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPL 292
Cdd:PRK08960 148 -------DSRYQltPALVERHWnadtvgaLVASPANPTGTLLSRDELAALSQALRARGGHLVVDEIYHGLTYGVDAASVL 220
|
170 180 190
....*....|....*....|....*....|
gi 515632818 293 KAfdkTDSVLLCGSYSKSL-CPGYRVGWVV 321
Cdd:PRK08960 221 EV---DDDAFVLNSFSKYFgMTGWRLGWLV 247
|
|
| GntR |
pfam00392 |
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ... |
4-66 |
4.59e-12 |
|
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.
Pssm-ID: 306822 [Multi-domain] Cd Length: 64 Bit Score: 61.09 E-value: 4.59e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515632818 4 YEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFV 66
Cdd:pfam00392 2 YEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
|
|
| PRK08912 |
PRK08912 |
aminotransferase; |
101-321 |
4.98e-12 |
|
aminotransferase;
Pssm-ID: 181580 Cd Length: 387 Bit Score: 67.31 E-value: 4.98e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 101 GVIPFGSAFPDpDLFPLPTLtrnlASAGRKMTGASviNNLPP--GSESLRRQIAQRYLQ-QGITVNHQ-DIVITSGAMEA 176
Cdd:PRK08912 27 GAINLGQGFPD-DPGPEDVR----RAAADALLDGS--NQYPPmmGLPELRQAVAAHYARfQGLDLDPEtEVMVTSGATEA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 177 LNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPIN-GLNIEQFENALqNQDVKACwLMTTFQNPTGTSLS 255
Cdd:PRK08912 100 LAAALLALVEPGDEVVLFQPLYDAYLPLIRRAGGVPRLVRLEPPHwRLPRAALAAAF-SPRTKAV-LLNNPLNPAGKVFP 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515632818 256 EQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKT-DSVLLCGSYSK--SLCpGYRVGWVV 321
Cdd:PRK08912 178 REELALLAEFCQRHDAVAICDEVWEHVVFDGRRHIPLMTLPGMrERTVKIGSAGKifSLT-GWKVGFVC 245
|
|
| PRK06207 |
PRK06207 |
pyridoxal phosphate-dependent aminotransferase; |
143-318 |
2.08e-11 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235742 Cd Length: 405 Bit Score: 65.56 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQRYLQ-QGITVNHQD-IVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLG--LNPIEVDVC 218
Cdd:PRK06207 79 GDADIRELLAARLAAfTGAPVDAADeLIITPGTQGALFLAVAATVARGDKVAIVQPDYFANRKLVEFFEgeMVPVQLDYL 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 219 PIN---GLNIEQFENALQnQDVKAcWLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKA- 294
Cdd:PRK06207 159 SADkraGLDLDQLEEAFK-AGVRV-FLFSNPNNPAGVVYSAEEIAQIAALARRYGATVIVDQLYSRLLYDGTSYTHLRAl 236
|
170 180
....*....|....*....|....*.
gi 515632818 295 -FDKTDSVLLCG-SYSKSLcPGYRVG 318
Cdd:PRK06207 237 pIDPENVITIMGpSKTESL-SGYRLG 261
|
|
| PRK09148 |
PRK09148 |
LL-diaminopimelate aminotransferase; |
142-432 |
9.71e-11 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181674 [Multi-domain] Cd Length: 405 Bit Score: 63.55 E-value: 9.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 142 PGsesLRRQIAQRYLQQ-GITVN-HQDIVITSGAMEAL-NLSlQTVTKSGDNVVIESPAF----YGALQAVERLGLNPIE 214
Cdd:PRK09148 71 PG---LRRAQAAYYARRfGVKLNpDTQVVATLGSKEGFaNMA-QAITAPGDVILCPNPSYpihaFGFIMAGGVIRSVPAE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 215 VDvcpinglniEQF----ENALQNQDVKACWLMTTF-QNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGhKP 289
Cdd:PRK09148 147 PD---------EEFfpalERAVRHSIPKPIALIVNYpSNPTAYVADLDFYKDVVAFAKKHDIIILSDLAYSEIYFDG-NP 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 290 KP--LKAFDKTDSVLLCGSYSKSLC-PGYRVGWVV-NTRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTHEsyDNHLRKLR 365
Cdd:PRK09148 217 PPsvLQVPGAKDVTVEFTSMSKTFSmAGWRMGFAVgNERLIAALTRVKSYLDYGAFTPIQVAATAALNGP--QDCIAEMR 294
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515632818 366 KnlVVRKERfiDVIKQYFPHS-IEIEEPAGGYLIWIRFSEKFD---SQQFHQLAIEQ-GISVASGDLFSEHG 432
Cdd:PRK09148 295 E--LYKKRR--DVLVESFGRAgWDIPPPAASMFAWAPIPEAFRhlgSLEFSKLLVEKaDVAVAPGVGFGEHG 362
|
|
| FadR |
COG2186 |
DNA-binding transcriptional regulator, FadR family [Transcription]; |
3-69 |
1.65e-10 |
|
DNA-binding transcriptional regulator, FadR family [Transcription];
Pssm-ID: 441789 [Multi-domain] Cd Length: 232 Bit Score: 61.10 E-value: 1.65e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515632818 3 RYEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVAPR 69
Cdd:COG2186 8 LAEQVAEQLRELILSGELKPGDRLPSERELAEQLGVSRTTVREALRALEALGLVEVRQGGGTFVREP 74
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
143-286 |
2.39e-10 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 62.01 E-value: 2.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQRYLQQ-GITVN-HQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPI 220
Cdd:PRK05957 66 GIPPLLEAITQKLQQDnGIELNnEQAIVVTAGSNMAFMNAILAITDPGDEIILNTPYYFNHEMAITMAGCQPILVPTDDN 145
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515632818 221 NGLNIEQFENALQNQdVKAcwlMTTF--QNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEG 286
Cdd:PRK05957 146 YQLQPEAIEQAITPK-TRA---IVTIspNNPTGVVYPEALLRAVNQICAEHGIYHISDEAYEYFTYDG 209
|
|
| PRK07681 |
PRK07681 |
LL-diaminopimelate aminotransferase; |
248-432 |
2.56e-10 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 181081 Cd Length: 399 Bit Score: 62.13 E-value: 2.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 248 NPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLL-CGSYSKSL-CPGYRVGWVV-NTR 324
Cdd:PRK07681 177 NPVPAMAHEDFFKEVIAFAKKHNIIVVHDFAYAEFYFDGNKPISFLSVPGAKEVGVeINSLSKSYsLAGSRIGYMIgNEE 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 325 FNDAIQKLQLLSTLSSSAPVQLGVAHFLTHEsyDNHLRKLRKNLVVRKERFIDVIKQYfphSIEIEEPAGGYLIWIRFSE 404
Cdd:PRK07681 257 IVRALTQFKSNTDYGVFLPIQKAACAALRNG--AAFCEKNRGIYQERRDTLVDGFRTF---GWNVDKPAGSMFVWAEIPK 331
|
170 180
....*....|....*....|....*....
gi 515632818 405 KFDSQQFHQLAIEQ-GISVASGDLFSEHG 432
Cdd:PRK07681 332 GWTSLSFAYALMDRaNVVVTPGHAFGPHG 360
|
|
| PLN00175 |
PLN00175 |
aminotransferase family protein; Provisional |
101-398 |
1.34e-09 |
|
aminotransferase family protein; Provisional
Pssm-ID: 215089 [Multi-domain] Cd Length: 413 Bit Score: 59.88 E-value: 1.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 101 GVIPFGSAFPDpdlFPLPTLTRNLA----SAGRKMTGASVinnlppGSESLRRQIAQRYLQQ-GITVN-HQDIVITSGAM 174
Cdd:PLN00175 55 GAINLGQGFPN---FDGPDFVKEAAiqaiRDGKNQYARGF------GVPELNSAIAERFKKDtGLVVDpEKEVTVTSGCT 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 175 EALNLSLQTVTKSGDNVVIESPaFYGALQAVERL-GLNPIEVDVCPIN-GLNIEQFENALQNqDVKACwLMTTFQNPTGT 252
Cdd:PLN00175 126 EAIAATILGLINPGDEVILFAP-FYDSYEATLSMaGAKIKTVTLRPPDfAVPEDELKAAFTS-KTRAI-LINTPHNPTGK 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 253 SLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGhkpkplkafDKTDSVLLCGSYSKSLC----------PGYRVGWVVN 322
Cdd:PLN00175 203 MFTREELELIASLCKENDVLAFTDEVYDKLAFEG---------DHISMASLPGMYERTVTmnslgktfslTGWKIGWAIA 273
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515632818 323 -TRFNDAIQKLQLLSTLSSSAPVQLGVAHFLthESYDNHLRKLRKNLVVRKERFIDVIKQYfphSIEIEEPAGGYLI 398
Cdd:PLN00175 274 pPHLTWGVRQAHSFLTFATATPMQWAAVAAL--RAPESYYEELKRDYSAKKDILVEGLKEV---GFKVYPSSGTYFV 345
|
|
| PRK09265 |
PRK09265 |
aminotransferase AlaT; Validated |
136-321 |
2.98e-09 |
|
aminotransferase AlaT; Validated
Pssm-ID: 181738 Cd Length: 404 Bit Score: 58.67 E-value: 2.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 136 VINNLP--------PGSESLRRQIAQRYLQQGIT-VNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAF--YGAlqA 204
Cdd:PRK09265 58 VIRNLPtaqgysdsKGLFSARKAIMQYYQQKGIPdVDVDDIYIGNGVSELIVMAMQALLNNGDEVLVPAPDYplWTA--A 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 205 VERLGLNPI------EVDVCPinglNIEQFEnALQNQDVKACWLMTTfQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDV 278
Cdd:PRK09265 136 VSLSGGKPVhylcdeEAGWFP----DLDDIR-SKITPRTKAIVIINP-NNPTGAVYSKELLEEIVEIARQHNLIIFADEI 209
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 515632818 279 YGDLYYEGHKPKPLKAFdKTDsvLLCGSY---SKS--LCpGYRVGWVV 321
Cdd:PRK09265 210 YDKILYDGAVHISIASL-APD--LLCVTFnglSKAyrVA-GFRVGWMV 253
|
|
| PRK09276 |
PRK09276 |
LL-diaminopimelate aminotransferase; Provisional |
248-432 |
4.31e-09 |
|
LL-diaminopimelate aminotransferase; Provisional
Pssm-ID: 181749 Cd Length: 385 Bit Score: 58.00 E-value: 4.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 248 NPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLL-CGSYSKSL-CPGYRVGWVV-NTR 324
Cdd:PRK09276 177 NPTGAVADLEFFEEVVDFAKKYDIIVCHDAAYSEIAYDGYKPPSFLEVPGAKDVGIeFHSLSKTYnMTGWRIGFAVgNAD 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 325 FNDAIQKLQLLSTLSSSAPVQL-GVAHFLTHESYDNHLRKLRKNlvvRKERFIDVIKQYfphSIEIEEPAGGYLIWIRFS 403
Cdd:PRK09276 257 LIAGLGKVKSNVDSGVFQAIQEaGIAALNGPQEVVEELRKIYQE---RRDILVEGLRKL---GLEVEPPKATFYVWAPVP 330
|
170 180 190
....*....|....*....|....*....|
gi 515632818 404 EKFDSQQFHQLAIEQ-GISVASGDLFSEHG 432
Cdd:PRK09276 331 KGYTSAEFATLLLDKaGVVVTPGNGFGEYG 360
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
142-289 |
7.12e-09 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 57.67 E-value: 7.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 142 PGSESLRRQIAqRYLQQ--GITVNHQDIVITSGAMEALNLSLQT-VTKSGDNVVIESPAF--YGAlqAVERLGLNPIEVD 216
Cdd:PTZ00377 115 AGYPFVRKAVA-AFIERrdGVPKDPSDIFLTDGASSGIKLLLQLlIGDPSDGVMIPIPQYplYSA--AITLLGGKQVPYY 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 217 VCPING--LNIEQFENALQ-----NQDVKACWLMTTfQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKP 289
Cdd:PTZ00377 192 LDEEKGwsLDQEELEEAYEqavrnGITPRALVVINP-GNPTGQVLTRDVMEEIIKFCYEKGIVLMADEVYQENIYDGEKP 270
|
|
| PRK09082 |
PRK09082 |
methionine aminotransferase; Validated |
101-442 |
1.00e-08 |
|
methionine aminotransferase; Validated
Pssm-ID: 181642 [Multi-domain] Cd Length: 386 Bit Score: 56.85 E-value: 1.00e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 101 GVIPFGSAFPDPDlfPLPTLTRNLASAGRkmTGAsviNNLPP--GSESLRRQIAQRYLQ-QGITVN-HQDIVITSGAMEA 176
Cdd:PRK09082 31 GAINLSQGFPDFD--GPPYLVEALAYAMA--AGH---NQYPPmtGVAALREAIAAKTARlYGRQYDaDSEITVTAGATEA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 177 LNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVdvcpinglnieqfenALQNQDVKACW--------------L 242
Cdd:PRK09082 104 LFAAILALVRPGDEVIVFDPSYDSYAPAIELAGGRAVRV---------------ALQPPDFRVDWqrfaaaisprtrliI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 243 MTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDK-TDSVLLCGSYSKSL-CPGYRVGWV 320
Cdd:PRK09082 169 LNTPHNPSGTVWSAADMRALWQLIAGTDIYVLSDEVYEHIVFDGAGHASVLRHPElRERAFVVSSFGKTYhVTGWKVGYC 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 321 VNTRFNDA-IQKLQLLSTLSSSAPVQLGVAHFLTHEsyDNHLRKLRKNLVVRKERFIDVIKQyfpHSIEIEEPAGGYLIW 399
Cdd:PRK09082 249 VAPAALSAeFRKVHQYNTFTVNTPAQLALADYLRAE--PEHYLELPAFYQAKRDRFRAALAN---SRFKLLPCEGTYFQL 323
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 515632818 400 IRFSE--KFDSQQFHQ-LAIEQGISVASGDLFSEHGRVDNAIRLNF 442
Cdd:PRK09082 324 VDYSAisDLDDVEFCQwLTREHGVAAIPLSVFYADPFPHRLVRLCF 369
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
152-313 |
1.12e-08 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 54.31 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 152 AQRYLQQGITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQ-AVERLGLNPIEVDV--CPINGLNIEQF 228
Cdd:cd01494 5 LEEKLARLLQPGNDKAVFVPSGTGANEAALLALLGPGDEVIVDANGHGSRYWvAAELAGAKPVPVPVddAGYGGLDVAIL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 229 ENALQNQDVKACWlmttFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLkaFDKTDSVLLCGsyS 308
Cdd:cd01494 85 EELKAKPNVALIV----ITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGASPAPGVLIP--EGGADVVTFSL--H 156
|
....*
gi 515632818 309 KSLCP 313
Cdd:cd01494 157 KNLGG 161
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
166-324 |
1.53e-08 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 56.30 E-value: 1.53e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 166 DIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPinglniEQFENALQNQDVKACWLMTT 245
Cdd:PRK06225 85 EALITAGATESLYLVMRAFLSPGDNAVTPDPGYLIIDNFASRFGAEVIEVPIYS------EECNYKLTPELVKENMDENT 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 246 F-------QNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDlYYEGHKPKPLKAFDKTdsvLLCGSYSKSL-CPGYRV 317
Cdd:PRK06225 159 RliylidpLNPLGSSYTEEEIKEFAEIARDNDAFLLHDCTYRD-FAREHTLAAEYAPEHT---VTSYSFSKIFgMAGLRI 234
|
....*..
gi 515632818 318 GWVVNTR 324
Cdd:PRK06225 235 GAVVATP 241
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
146-321 |
1.74e-08 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 56.67 E-value: 1.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 146 SLRRQIAQRYLQQGIT-VNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVdVC------ 218
Cdd:PRK13355 189 SARKAIMQYAQLKGLPnVDVDDIYTGNGVSELINLSMSALLDDGDEVLIPSPDYPLWTACVNLAGGTAVHY-RCdeqsew 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 219 -PinglNIEQFENALQNQdVKACWLMTTfQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEG--HKPKPLKAF 295
Cdd:PRK13355 268 yP----DIDDIRSKITSR-TKAIVIINP-NNPTGALYPREVLQQIVDIAREHQLIIFSDEIYDRLVMDGleHTSIASLAP 341
|
170 180 190
....*....|....*....|....*....|
gi 515632818 296 DktdsvLLCGSY---SKS-LCPGYRVGWVV 321
Cdd:PRK13355 342 D-----LFCVTFsglSKShMIAGYRIGWMI 366
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
90-320 |
3.79e-08 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 55.50 E-value: 3.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 90 LFDFLKSSSAEGVIPFGSAfpDPDLFPLPTLTRNLASAGRKMTGASVINNLPPGSESL--RRQIAQrYLQQGI--TVNHQ 165
Cdd:PLN02187 56 LFDNCGKDVNKTILPLGHG--DPSVYPCFRTCIEAEDAVVDVLRSGKGNSYGPGAGILpaRRAVAD-YMNRDLphKLTPE 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 166 DIVITSGAMEALNLSLQTVTKSGDNVVIESPAF--YGALQAVErlGLNPIEVDVCPING--LNIEQFEnALQNQDVKACW 241
Cdd:PLN02187 133 DIFLTAGCNQGIEIVFESLARPNANILLPRPGFphYDARAAYS--GLEVRKFDLLPEKEweIDLEGIE-AIADENTVAMV 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 242 LMTTfQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDKTDSVLLCGSYSKS-LCPGYRVGWV 320
Cdd:PLN02187 210 VINP-NNPCGNVYSHDHLKKVAETARKLGIMVISDEVYDRTIFGDNPFVSMGKFASIVPVLTLAGISKGwVVPGWKIGWI 288
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
111-321 |
6.11e-08 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 54.74 E-value: 6.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 111 DPDlFPLPTLTRNLASA--GRKMTGASVINNLPpgseSLRRQIAQRYLQQ-GITVNHQDIVITSGAMEALNLSLQTVTKS 187
Cdd:PRK06107 42 EPD-FDTPDHIKQAAVAaiERGETKYTLVNGTP----ALRKAIIAKLERRnGLHYADNEITVGGGAKQAIFLALMATLEA 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 188 GDNVVIESPAFYGALQAVERLGLNPIEVDvCP-ING--LNIEQFENALQNqdvKACWL-MTTFQNPTGTSLSEQAKRRVV 263
Cdd:PRK06107 117 GDEVIIPAPYWVSYPDMVLANDGTPVIVA-CPeEQGfkLTPEALEAAITP---RTRWLiLNAPSNPTGAVYSRAELRALA 192
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515632818 264 EIAEQH-GTYIIEDDVYGDLYYEGHKPKPLKAFDK--TDSVLLCGSYSKSLC-PGYRVGWVV 321
Cdd:PRK06107 193 DVLLRHpHVLVLTDDIYDHIRFDDEPTPHLLAAAPelRDRVLVTNGVSKTYAmTGWRIGYAA 254
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
248-366 |
8.13e-08 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 54.19 E-value: 8.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 248 NPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKafDKTDSVllCG----SYSKSL-CPGYRVGW--V 320
Cdd:PRK06855 182 NPTGAVYPKEILREIVDIAREYDLFIICDEIYNNIVYNGKKTVPLS--EVIGDV--PGialkGISKELpWPGSRCGWieV 257
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 515632818 321 VNT-------RFNDAIQKLQLLSTLSSSAPvQLGVAHFLTHESYDNHLRKLRK 366
Cdd:PRK06855 258 YNAdkdevfkKYINSILNAKMIEVCSTTLP-QMAIPRIMSHPEYKNYLKERNK 309
|
|
| PRK08068 |
PRK08068 |
transaminase; Reviewed |
248-433 |
3.17e-07 |
|
transaminase; Reviewed
Pssm-ID: 181219 Cd Length: 389 Bit Score: 52.23 E-value: 3.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 248 NPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPkplKAFDKTDSVLLCG----SYSKSL-CPGYRVGWVV- 321
Cdd:PRK08068 178 NPTGAVATKAFFEETVAFAKKHNIGVVHDFAYGAIGFDGQKP---VSFLQTPGAKDVGielyTLSKTFnMAGWRVAFAVg 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 322 NTRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTheSYDNHLRKLRKNLVVRKERFIDVIKQYfphSIEIEEPAGGYLIWIR 401
Cdd:PRK08068 255 NESVIEAINLLQDHLFVSLFGAIQDAAIEALL--SDQSCVAELVARYESRRNAFISACREI---GWEVDAPKGSFFAWMP 329
|
170 180 190
....*....|....*....|....*....|...
gi 515632818 402 FSEKFDSQQFHQLAIEQ-GISVASGDLFSEHGR 433
Cdd:PRK08068 330 VPKGYTSEQFADLLLEKaHVAVAPGNGFGEHGE 362
|
|
| GntR |
COG1802 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
5-68 |
3.32e-06 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441407 [Multi-domain] Cd Length: 222 Bit Score: 47.99 E-value: 3.32e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515632818 5 EELAKDIRTQIANNTWRSGEKIPSVRMsCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVAP 68
Cdd:COG1802 14 EQVYEALREAILSGELPPGERLSEAEL-AERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAP 76
|
|
| PLN02231 |
PLN02231 |
alanine transaminase |
143-284 |
3.87e-06 |
|
alanine transaminase
Pssm-ID: 177876 [Multi-domain] Cd Length: 534 Bit Score: 49.17 E-value: 3.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 143 GSESLRRQIAQRY-LQQGITVNHQDIVITSGAMEALNLSLQTVTKS-GDNVVIESPAF--YGALQAVERLGLNPIEVDVC 218
Cdd:PLN02231 169 GIKGLRDAIAAGIeARDGFPADPNDIFLTDGASPAVHMMMQLLIRSeKDGILCPIPQYplYSASIALHGGTLVPYYLDEA 248
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515632818 219 PINGLNIEQFENALQNQ-----DVKACWLMTTfQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYY 284
Cdd:PLN02231 249 TGWGLEISELKKQLEDArskgiTVRALVVINP-GNPTGQVLAEENQRDIVEFCKQEGLVLLADEVYQENVY 318
|
|
| PRK11523 |
PRK11523 |
transcriptional regulator ExuR; |
4-66 |
2.09e-04 |
|
transcriptional regulator ExuR;
Pssm-ID: 183176 [Multi-domain] Cd Length: 253 Bit Score: 42.91 E-value: 2.09e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515632818 4 YEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFV 66
Cdd:PRK11523 10 YQQLAAELKERIEQGVYLVGDKLPAERFIADEKNVSRTVVREAIIMLEVEGYVEVRKGSGIHV 72
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
165-443 |
2.82e-04 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 42.85 E-value: 2.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 165 QDIVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVCPiNGLNIEQFENALQNQDVKACWLMT 244
Cdd:PRK12414 91 SEVTVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSP-EDFRVNWDEVAAAITPRTRMIIVN 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 245 TFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPKPLKAFDK--TDSVLLcGSYSKSL-CPGYRVGW-V 320
Cdd:PRK12414 170 TPHNPSATVFSAADLARLAQLTRNTDIVILSDEVYEHVVFDGARHHSMARHRElaERSVIV-SSFGKSYhVTGWRVGYcL 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 321 VNTRFNDAIQKLQLLSTLSSSAPVQLGVAHFLTH-ESY----DNHLRKlrKNLVVRK---ERFidvikqyfphsiEIEEP 392
Cdd:PRK12414 249 APAELMDEIRKVHQFMVFSADTPMQHAFAEALAEpASYlglgAFYQRK--RDLLARElagSRF------------ELLPS 314
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 515632818 393 AGGYLIWIR---FSEKFDSQQFHQLAIEQGISVASGDLFSEHGRVDNAIRLNFS 443
Cdd:PRK12414 315 EGSFFMLARfrhFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDTGLIRLSFS 368
|
|
| PRK11402 |
PRK11402 |
transcriptional regulator PhoB; |
4-66 |
4.13e-04 |
|
transcriptional regulator PhoB;
Pssm-ID: 183118 [Multi-domain] Cd Length: 241 Bit Score: 41.74 E-value: 4.13e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515632818 4 YEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFV 66
Cdd:PRK11402 11 YATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFV 73
|
|
| avtA |
PRK09440 |
valine--pyruvate transaminase; Provisional |
248-428 |
4.21e-04 |
|
valine--pyruvate transaminase; Provisional
Pssm-ID: 236517 Cd Length: 416 Bit Score: 42.53 E-value: 4.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 248 NPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDlyyeghkPKPLKAF-DKT----DSVLLCGSYSKSLCPGYRVGWVV- 321
Cdd:PRK09440 190 NPTGNVLTDEELEKLDALARQHNIPLLIDNAYGP-------PFPGIIFsEATplwnPNIILCMSLSKLGLPGVRCGIVIa 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 322 NTRFndaIQKLQLLSTLSSSAPVQLGVAhfLTHESY-DNHLRKLRKNlVVR---KERF---IDVIKQYFPH-SIEIEEPA 393
Cdd:PRK09440 263 DEEI---IEALSNMNGIISLAPGRLGPA--IAAEMIeSGDLLRLSET-VIRpfyRQKVqlaIALLRRYLPDePCLIHKPE 336
|
170 180 190
....*....|....*....|....*....|....*.
gi 515632818 394 GGYLIWIRFSE-KFDSQQFHQLAIEQGISVASGDLF 428
Cdd:PRK09440 337 GAIFLWLWFKDlPITTEELYQRLKARGVLVVPGHYF 372
|
|
| PRK14999 |
PRK14999 |
histidine utilization repressor; Provisional |
4-67 |
4.50e-04 |
|
histidine utilization repressor; Provisional
Pssm-ID: 184961 [Multi-domain] Cd Length: 241 Bit Score: 41.84 E-value: 4.50e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515632818 4 YEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVA 67
Cdd:PRK14999 14 YETVKQDICKKIAGGVWQPHDRIPSEAELVAQYGFSRMTINRALRELTDEGWLVRLQGVGTFVA 77
|
|
| PRK10225 |
PRK10225 |
Uxu operon transcriptional regulator; |
4-87 |
9.42e-04 |
|
Uxu operon transcriptional regulator;
Pssm-ID: 182318 [Multi-domain] Cd Length: 257 Bit Score: 40.77 E-value: 9.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 4 YEELAKDIRTQIANNTWRSGEKIPSVRMSCRNYNVSNSTVLQAYQLLESEGWIIAKPQSGYFVaprldgVDYAQPLVSEK 83
Cdd:PRK10225 11 YQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYV------LDSSGSHNTDS 84
|
....
gi 515632818 84 KAIN 87
Cdd:PRK10225 85 PDAN 88
|
|
| PRK06290 |
PRK06290 |
LL-diaminopimelate aminotransferase; |
248-321 |
9.62e-04 |
|
LL-diaminopimelate aminotransferase;
Pssm-ID: 235772 Cd Length: 410 Bit Score: 41.56 E-value: 9.62e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515632818 248 NPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGhkpKPLkAFDKTDSVLLCG----SYSKSL-CPGYRVGWVV 321
Cdd:PRK06290 190 NPTGAVATKEFYEEVVDFAKENNIIVVQDAAYAALTFDG---KPL-SFLSVPGAKEVGveihSLSKAYnMTGWRLAFVV 264
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
168-276 |
1.61e-03 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 40.65 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 168 VITSGAMEALNLSLQTVTKSGDNVVIeSPAFYGALQAVERLGLNPIEVDVCPINGLNIEQFENALQnQDVKACWLmTTFQ 247
Cdd:cd00614 59 LAFSSGMAAISTVLLALLKAGDHVVA-SDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIK-PETKLVYV-ESPT 135
|
90 100
....*....|....*....|....*....
gi 515632818 248 NPTGTSLSeqaKRRVVEIAEQHGTYIIED 276
Cdd:cd00614 136 NPTLKVVD---IEAIAELAHEHGALLVVD 161
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
167-403 |
1.90e-03 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 40.64 E-value: 1.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 167 IVITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVE-RLGLN--PIEVDVCpiNGLNI--EQFENALQ-----NQD 236
Cdd:PLN02607 123 IVLTAGATAANELLTFILADPGDALLVPTPYYPGFDRDLRwRTGVKivPIHCDSS--NNFQVtpQALEAAYQeaeaaNIR 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 237 VKACwLMTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYG-------DLYYEGHKPKPLKAFDKTDSVLLCGSYSK 309
Cdd:PLN02607 201 VRGV-LITNPSNPLGATVQRSVLEDILDFVVRKNIHLVSDEIYSgsvfsasEFVSVAEIVEARGYKGVAERVHIVYSLSK 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 310 SL-CPGYRVGWVVNtrFNDAIQKLQLLSTLSS--SAPVQLGVAHFLTHESY-DNHLRKLRKNLVVRKERFIDVIKQyfpH 385
Cdd:PLN02607 280 DLgLPGFRVGTIYS--YNDKVVTTARRMSSFTlvSSQTQHLLASMLSDEEFtENYIRTNRERLRKRYEMIVQGLRR---A 354
|
250
....*....|....*...
gi 515632818 386 SIEIEEPAGGYLIWIRFS 403
Cdd:PLN02607 355 GIECLKGNAGLFCWMNLS 372
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
168-293 |
2.62e-03 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 40.20 E-value: 2.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 168 VITSGAMEALNLSLQTVTKSGDNVViESPAFYGALQAVERLGLNPIEVDVCPINGLNIEQFENALQnQDVKACWLMTtfq 247
Cdd:PRK06234 83 VVAASGMGAISSSLWSALKAGDHVV-ASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALK-ANTKVVYLET--- 157
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 515632818 248 nPTGTSLSEQAKRRVVEIAEQH--GTYIIEDDVYGDLYYEghkpKPLK 293
Cdd:PRK06234 158 -PANPTLKVTDIKAISNIAHENnkECLVFVDNTFCTPYIQ----RPLQ 200
|
|
| CsdA |
COG0520 |
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism]; |
167-276 |
3.48e-03 |
|
Selenocysteine lyase/Cysteine desulfurase [Amino acid transport and metabolism];
Pssm-ID: 440286 [Multi-domain] Cd Length: 396 Bit Score: 39.74 E-value: 3.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 167 IVITSGAMEALNL---SLQTVtKSGDNVVIeSPAFYGA-----LQAVERLGlnpIEVDVCPIN---GLNIEQFENALqNQ 235
Cdd:COG0520 80 IIFTRGTTEAINLvayGLGRL-KPGDEILI-TEMEHHSnivpwQELAERTG---AEVRVIPLDedgELDLEALEALL-TP 153
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 515632818 236 DVKacwLM--------TTFQNPTgtslseqakRRVVEIAEQHGTYIIED 276
Cdd:COG0520 154 RTK---LVavthvsnvTGTVNPV---------KEIAALAHAHGALVLVD 190
|
|
| PLN02450 |
PLN02450 |
1-aminocyclopropane-1-carboxylate synthase |
120-318 |
4.93e-03 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178069 [Multi-domain] Cd Length: 468 Bit Score: 39.35 E-value: 4.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 120 LTRNLASAGRKMTGASVI---------NNLPPGSESLRRQIAQrylQQG--ITVNHQDIVITSGAMEALNLSLQTVTKSG 188
Cdd:PLN02450 59 LAKNPDAAGLKRNGQSIFrelalfqdyHGLPAFKNALAEFMSE---IRGnkVTFDPNKLVLTAGATSANETLMFCLAEPG 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 189 DNVVIESPAFYGALQAVE-RLGlnpieVDVCPI-----NGLNI------EQFENAL-QNQDVKACwLMTTFQNPTGTSLS 255
Cdd:PLN02450 136 DAFLLPTPYYPGFDRDLKwRTG-----VEIVPIhcsssNGFQItesaleEAYQQAQkLNLKVKGV-LITNPSNPLGTTTT 209
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515632818 256 EQAKRRVVEIAEQHGTYIIEDDVYGDLYY---------EGHKPKPLKAFDKTDSVLLCGSYSKSL-CPGYRVG 318
Cdd:PLN02450 210 RTELNLLVDFITAKNIHLISDEIYSGTVFdspgfvsvmEVLKDRKLENTDVSNRVHIVYSLSKDLgLPGFRVG 282
|
|
| PRK05839 |
PRK05839 |
succinyldiaminopimelate transaminase; |
134-320 |
5.40e-03 |
|
succinyldiaminopimelate transaminase;
Pssm-ID: 180281 Cd Length: 374 Bit Score: 38.90 E-value: 5.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 134 ASVINNLPP--GSESLRRqiAQR-YLQQ--GITVNHQDIVITSGAMEALNLSLQTVTKSGDNVVIESP-AFY----GALQ 203
Cdd:PRK05839 50 AHLLNKYPKsaGEESLRE--AQRgFFKRrfKIELKENELIPTFGTREVLFNFPQFVLFDKQNPTIAYPnPFYqiyeGAAI 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 204 AVERlglnpiEVDVCPINGLNieQFENALQNQDVKACWL--MTTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGD 281
Cdd:PRK05839 128 ASRA------KVLLMPLTKEN--DFTPSLNEKELQEVDLviLNSPNNPTGRTLSLEELIEWVKLALKHDFILINDECYSE 199
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 515632818 282 LYYEGHKPKPLKAFDKTD-----SVLLCGSYSK-SLCPGYRVGWV 320
Cdd:PRK05839 200 IYENTPPPSLLEASILVGnesfkNVLVINSISKrSSAPGLRSGFI 244
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
165-375 |
5.78e-03 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 38.56 E-value: 5.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 165 QDIVITSGAMEALNLsLQTVTKSGDNVVIESPAfYGALQAVERLGLNPIevdvcpING-LNIEQFENALQNQDVKacwLM 243
Cdd:PRK08354 55 EPIVITAGITEALYL-IGILALRDRKVIIPRHT-YGEYERVARFFAARI------IKGpNDPEKLEELVERNSVV---FF 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 244 TTFQNPTGTSLSEQAKRRVVEIAEQHGTYIIEDDVYGDLYYEGHKPkplkafdKTDSVLLCGSYSKSL-CPGYRVGWVVN 322
Cdd:PRK08354 124 CNPNNPDGKFYNFKELKPLLDAVEDRNALLILDEAFIDFVKKPESP-------EGENIIKLRTFTKSYgLPGIRVGYVKG 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 515632818 323 trFNDAIQKLQLLSTLSSsapvqLGVA--HFLTHESYDnHLRKLRKNLVVRKERF 375
Cdd:PRK08354 197 --FEEAFRSVRMPWSIGS-----TGYAflEFLIEDDFE-HLRKTMPLIWREKERF 243
|
|
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
150-280 |
6.12e-03 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 39.08 E-value: 6.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515632818 150 QIAQRYLQQGITVNHQ-----DIVITSG---AMEALNLSLQT--VTKSGDNVVIESPAF--YGALQAVERLGLNPIEVDV 217
Cdd:PRK09275 142 KIVKDYLRQEMCGGRPpkgefDLFAVEGgtaAMCYIFDSLKEngLLKAGDKIALMTPIFtpYLEIPELPRYDLEVVHINA 221
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515632818 218 CPINGLNIEQFE-NALQNQDVKACWLMTTfQNPTGTSLSEQAKRRVVEIAEQHGT--YIIEDDVYG 280
Cdd:PRK09275 222 DEENEWQYPDSElEKLRDPSIKALFLVNP-SNPPSVAMSDESLEKIADIVNEKRPdlMIITDDVYG 286
|
|
| SepCysS |
cd06452 |
Sep-tRNA:Cys-tRNA synthase. This family belongs to the pyridoxal phosphate (PLP)-dependent ... |
169-215 |
8.20e-03 |
|
Sep-tRNA:Cys-tRNA synthase. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Cys-tRNA(Cys) is produced by O-phosphoseryl-tRNA synthetase which ligates O-phosphoserine (Sep) to tRNA(Cys), and Sep-tRNA:Cys-tRNA synthase (SepCysS) converts Sep-tRNA(Cys) to Cys-tRNA(Cys), in methanogenic archaea. SepCysS forms a dimer, each monomer is composed of a large and small domain; the larger, a typical pyridoxal 5'-phosphate (PLP)-dependent-like enzyme fold. In the active site of each monomer, PLP is covalently bound to a conserved Lys residue near the dimer interface.
Pssm-ID: 99745 Cd Length: 361 Bit Score: 38.53 E-value: 8.20e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 515632818 169 ITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEV 215
Cdd:cd06452 64 VTPGAREGKFAVMHSLCEKGDWVVVDGLAHYTSYVAAERAGLNVREV 110
|
|
| PRK09331 |
PRK09331 |
Sep-tRNA:Cys-tRNA synthetase; Provisional |
166-234 |
8.39e-03 |
|
Sep-tRNA:Cys-tRNA synthetase; Provisional
Pssm-ID: 236469 Cd Length: 387 Bit Score: 38.37 E-value: 8.39e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515632818 166 DIV-ITSGAMEALNLSLQTVTKSGDNVVIESPAFYGALQAVERLGLNPIEVDVC--PINGLNIEQFENALQN 234
Cdd:PRK09331 79 DEArVTHGAREGKFAVMHSLCKKGDYVVLDGLAHYTSYVAAERAGLNVREVPKTgyPEYKITPEAYAEKIEE 150
|
|
| |
