LonB-like, AAA domain; This entry includes a wide variety of AAA domains, including some that ...
318-447
1.85e-71
LonB-like, AAA domain; This entry includes a wide variety of AAA domains, including some that have lost essential nucleotide binding residues in the P-loop. This domain is found in Lon proteases from archaea and bacteria.
Pssm-ID: 463946 [Multi-domain] Cd Length: 133 Bit Score: 229.61 E-value: 1.85e-71
LonB-like, AAA domain; This entry includes a wide variety of AAA domains, including some that ...
318-447
1.85e-71
LonB-like, AAA domain; This entry includes a wide variety of AAA domains, including some that have lost essential nucleotide binding residues in the P-loop. This domain is found in Lon proteases from archaea and bacteria.
Pssm-ID: 463946 [Multi-domain] Cd Length: 133 Bit Score: 229.61 E-value: 1.85e-71
Archaeal LonB, AAA+ ATPase LID domain; The species-specific Lon-insertion domain (LID) is ...
475-539
3.05e-24
Archaeal LonB, AAA+ ATPase LID domain; The species-specific Lon-insertion domain (LID) is characteriztic of Lon proteases (also known as endopeptidase La) and is fused to the AAA+ module. Bacterial and eukaryotic Lons (LonA) have a LID at the N-terminal of AAA+ module; in archaeal Lons (LonB) the LID, represented in this entry, is inserted within the AAA+ module in a series of transmembrane segments known as the membrane-anchoring region (MA). In the Lon-like protease LonC, which does not have ATPase activity, the LID is also within the AAA-like module similar to LonBs; in this case, it is predicted to contain coiled-coil regions rather than transmembrane segments.
Pssm-ID: 466585 [Multi-domain] Cd Length: 65 Bit Score: 96.34 E-value: 3.05e-24
Lon-like LonC helical domain; This domain represents the helical domain found in the Lon-like ...
87-120
2.73e-11
Lon-like LonC helical domain; This domain represents the helical domain found in the Lon-like LonC protease from Meiothermus taiwanensis, a Lon-like protease with no ATPase activity.
Pssm-ID: 466586 Cd Length: 34 Bit Score: 58.53 E-value: 2.73e-11
Lon protease (S16) C-terminal proteolytic domain; The Lon serine proteases must hydrolyse ATP ...
649-753
2.17e-08
Lon protease (S16) C-terminal proteolytic domain; The Lon serine proteases must hydrolyse ATP to degrade protein substrates. In Escherichia coli, these proteases are involved in turnover of intracellular proteins, including abnormal proteins following heat-shock. The active site for protease activity resides in a C-terminal domain. The Lon proteases are classified as family S16 in Merops.
Pssm-ID: 428442 [Multi-domain] Cd Length: 205 Bit Score: 54.94 E-value: 2.17e-08
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.
The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence.
(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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(labeled illustration) Four types of hits can be shown, as available,
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specific hits meet or exceed a domain-specific e-value threshold
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the domain superfamily to which the specific and non-specific hits belong
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