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Conserved domains on  [gi|515650673|ref|WP_017083273|]
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MULTISPECIES: ABC transporter permease subunit [Vibrio]

Protein Classification

ABC transporter permease( domain architecture ID 11467926)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0140359|GO:0042626|GO:0043190|GO:0016020
PubMed:  17723295|2229036|18535149|25750732|24638992|16375896|1970642
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
1-320 6.58e-169

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


:

Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 471.63  E-value: 6.58e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPWAIQDFWPGWLSYITELSTLNFGLSKH-GAPIIDELVVVFPATLEL 79
Cdd:COG4168    1 MLIYLLRRLNLLLITLLILSLISFSLLYRDPLNPLSDASLFSGYLFYLQNLLQGDFGISSInGEPILEQLLTVFPATLEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  80 CFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMFPVGGRYDLLYEIEHVTGFA 159
Cdd:COG4168   81 CFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLGWLPVSGRYNLLYEIPPVTGFA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 160 MIDAFFAEGRYRAHALQSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPP 239
Cdd:COG4168  161 LIDAWLSDSPYRLKAIQSALQHLILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 240 IIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVRKEWYAN 319
Cdd:COG4168  241 IIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVIIVNILSDILGALLNPLKRKEWYAL 320


                 .
gi 515650673 320 K 320
Cdd:COG4168  321 R 321
 
Name Accession Description Interval E-value
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
1-320 6.58e-169

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 471.63  E-value: 6.58e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPWAIQDFWPGWLSYITELSTLNFGLSKH-GAPIIDELVVVFPATLEL 79
Cdd:COG4168    1 MLIYLLRRLNLLLITLLILSLISFSLLYRDPLNPLSDASLFSGYLFYLQNLLQGDFGISSInGEPILEQLLTVFPATLEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  80 CFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMFPVGGRYDLLYEIEHVTGFA 159
Cdd:COG4168   81 CFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLGWLPVSGRYNLLYEIPPVTGFA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 160 MIDAFFAEGRYRAHALQSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPP 239
Cdd:COG4168  161 LIDAWLSDSPYRLKAIQSALQHLILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 240 IIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVRKEWYAN 319
Cdd:COG4168  241 IIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVIIVNILSDILGALLNPLKRKEWYAL 320


                 .
gi 515650673 320 K 320
Cdd:COG4168  321 R 321
PRK15110 PRK15110
peptide ABC transporter permease SapB;
1-318 1.52e-124

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 359.39  E-value: 1.52e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPWAIQDFWPGWLSYITELSTLNFGLSK-HGAPIIDELVVVFPATLEL 79
Cdd:PRK15110   1 MIIFTLRRLLLLIVTLFLLTLVGFSLSYFTPHAPLQGASLWDAWVFWFNGLLHWDFGVSSiNGQPISEQLKEVFPATMEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  80 CFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMFPVGGRYDLLYEIEHVTGFA 159
Cdd:PRK15110  81 CILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 160 MIDAFFAEGRYRAHALQSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPP 239
Cdd:PRK15110 161 LIDAWLSDSPWRDEMIMSAIRHMILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515650673 240 IIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVRKEWYA 318
Cdd:PRK15110 241 VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLSDILGAMANPLKHKEWYA 319
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 91-314 8.39e-22

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 90.44  E-value: 8.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   91 GIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLhfemfpvggrydllyeiehvtgfamidaffaegry 170
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL----------------------------------- 45

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  171 rahalqSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPPIIPKVGVQLSS 250
Cdd:pfam00528  46 ------SILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGG 119

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515650673  251 MLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVRK 314
Cdd:pfam00528 120 ALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 73-294 8.59e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.84  E-value: 8.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  73 FPATLELCFFAFVLALFIGIPFGTIAGMRQGKfVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMfpvggrydllyei 152
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK-LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 153 ehvtgfamidaffaegryrahalqSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHV 232
Cdd:cd06261   67 ------------------------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRII 122

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515650673 233 LRNAIPPIIPKVGVQLSSMLTLAIITESIFN----WPGIGRWLLDALSNQDYVSIQAGVIVVATLV 294
Cdd:cd06261  123 LPLALPPILTGLVLAFARALGEFALVSFLGGgeapGPGTGLLLIFAILFPGDLGVAAAVALILLLL 188
 
Name Accession Description Interval E-value
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
1-320 6.58e-169

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 471.63  E-value: 6.58e-169
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPWAIQDFWPGWLSYITELSTLNFGLSKH-GAPIIDELVVVFPATLEL 79
Cdd:COG4168    1 MLIYLLRRLNLLLITLLILSLISFSLLYRDPLNPLSDASLFSGYLFYLQNLLQGDFGISSInGEPILEQLLTVFPATLEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  80 CFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMFPVGGRYDLLYEIEHVTGFA 159
Cdd:COG4168   81 CFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLGWLPVSGRYNLLYEIPPVTGFA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 160 MIDAFFAEGRYRAHALQSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPP 239
Cdd:COG4168  161 LIDAWLSDSPYRLKAIQSALQHLILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKAAATRGLSRFTIIRRHVLRNALPP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 240 IIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVRKEWYAN 319
Cdd:COG4168  241 IIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVIIVNILSDILGALLNPLKRKEWYAL 320


                 .
gi 515650673 320 K 320
Cdd:COG4168  321 R 321
PRK15110 PRK15110
peptide ABC transporter permease SapB;
1-318 1.52e-124

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 359.39  E-value: 1.52e-124
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPWAIQDFWPGWLSYITELSTLNFGLSK-HGAPIIDELVVVFPATLEL 79
Cdd:PRK15110   1 MIIFTLRRLLLLIVTLFLLTLVGFSLSYFTPHAPLQGASLWDAWVFWFNGLLHWDFGVSSiNGQPISEQLKEVFPATMEL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  80 CFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMFPVGGRYDLLYEIEHVTGFA 159
Cdd:PRK15110  81 CILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 160 MIDAFFAEGRYRAHALQSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPP 239
Cdd:PRK15110 161 LIDAWLSDSPWRDEMIMSAIRHMILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515650673 240 IIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVRKEWYA 318
Cdd:PRK15110 241 VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLSDILGAMANPLKHKEWYA 319
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-313 9.63e-89

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 268.09  E-value: 9.63e-89
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRL-----------DQTSPWAI----------QDFWPGWLSYITELSTLNFGLS 59
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLlpgdpaaallgPRATPEAIaalraelgldQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  60 -KHGAPIIDELVVVFPATLELCFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFE 138
Cdd:COG0601   81 fVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 139 MFPVGGRYDLLyeiehvtgfamidaffaegryraHALQSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAAR 218
Cdd:COG0601  161 WLPVSGRVSPW-----------------------EDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTAR 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 219 IKGLSTREIVTQHVLRNAIPPIIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTAN 298
Cdd:COG0601  218 AKGLSERRVLLRHALRNALIPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVN 297

                        330
                 ....*....|....*
gi 515650673 299 ILSDLLGAMVNPLVR 313
Cdd:COG0601  298 LLVDLLYALLDPRIR 312
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-313 2.06e-65

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 209.28  E-value: 2.06e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPWAI----------------------QDFWPGWLSYITELSTLNFGL 58
Cdd:PRK10914   1 MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMImagergisperhaqllaelgldKPMWQQYLHYIWGVMHGDLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  59 S-KHGAPIIDELVVVFPATLELCFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHF 137
Cdd:PRK10914  81 SlKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 138 EMFPVGGRYD---LLYEIEHVTGFAMIDAFF--AEGRYRahalqSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQN 212
Cdd:PRK10914 161 NLTPVSGRVSdmvFLDDSNPLTGFMLIDTAIwgEDGNFI-----DAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGED 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 213 YIRAARIKGLSTREIVTQHVLRNAIPPIIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVAT 292
Cdd:PRK10914 236 YIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVAT 315

                        330       340
                 ....*....|....*....|.
gi 515650673 293 LVLTANILSDLLGAMVNPLVR 313
Cdd:PRK10914 316 MIILVNLLVDLLYGVVNPRIR 336
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-313 3.69e-44

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 153.31  E-value: 3.69e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPwAI-------------------------QDFWPGWLSYITELSTLN 55
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDP-ALdylrlsnlpptpemlastrtmlgldQPLYVQYGTWLWKALHLD 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  56 FGLS-KHGAPIIDELVVVFPATLELCFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFS 134
Cdd:PRK10352  80 FGISfATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFS 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 135 LHFEMFPVGGRYDLlyeiehvtgfamidaffaegryrahalqsviEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYI 214
Cdd:PRK10352 160 VYLQWLPAMGYGGW-------------------------------QHIILPAVSIAFMSLAINARLLRASMLEVAGQRHV 208

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 215 RAARIKGLSTREIVTQHVLRNAIPPIIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLV 294
Cdd:PRK10352 209 TWARLRGLSERQVERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVF 288

                        330
                 ....*....|....*....
gi 515650673 295 LTANILSDLLGAMVNPLVR 313
Cdd:PRK10352 289 VVCNLIVDLLNAALDPRIR 307
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-313 6.54e-41

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 144.44  E-value: 6.54e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   1 MFWYTLRRVNLFIITLGILTLVGFALLRLDQTSPWAIQ-------------------DFWPGWLSYITELSTLNFGLS-K 60
Cdd:PRK09471   1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGErtlppevmanieakyhlndPIMTQYFSYLKQLAHGDFGPSfK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  61 HGAPIIDELVVV-FPATLELCFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEM 139
Cdd:PRK09471  81 YKDYSVNDLVASsFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHW 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 140 FPVGGRYDllyeiehvtgfamidaffaegryrahalqSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARI 219
Cdd:PRK09471 161 LPGGGWNG-----------------------------GALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARA 211

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 220 KGLSTREIVTQHVLRNAIPPIIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANI 299
Cdd:PRK09471 212 KGLPMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNA 291

                        330
                 ....*....|....
gi 515650673 300 LSDLLGAMVNPLVR 313
Cdd:PRK09471 292 IVDVLYAVIDPKIR 305
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 27-313 1.45e-30

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 117.12  E-value: 1.45e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  27 LRLDQTSPwaiQDFWpgwlSYITELSTLNFGLS-KHGAPIIDELVVVFPATLELCFFAFVLALFIGIPFGTIAGMRQGKF 105
Cdd:PRK15081  55 LGLDQPLP---HQFW----HYISNALQGDFGTSmVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRW 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 106 VDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMFPVGGrydllyeiehvtgfamidaffaegryrahalQSVIEHMALP 185
Cdd:PRK15081 128 PDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWLPTVG-------------------------------ADSWQHYILP 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 186 CLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPPIIPKVGVQLSSMLTLAIITESIFNWP 265
Cdd:PRK15081 177 SLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWP 256

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 515650673 266 GIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVR 313
Cdd:PRK15081 257 GLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 91-314 8.39e-22

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 90.44  E-value: 8.39e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673   91 GIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFSLhfemfpvggrydllyeiehvtgfamidaffaegry 170
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAIL----------------------------------- 45

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  171 rahalqSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPPIIPKVGVQLSS 250
Cdd:pfam00528  46 ------SILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGG 119

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515650673  251 MLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVVATLVLTANILSDLLGAMVNPLVRK 314
Cdd:pfam00528 120 ALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 62-310 6.32e-14

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 71.70  E-value: 6.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  62 GAPIIDELVVVFPATLELCFFAFVLALFIGIPFGTIAGMRQGKFVDTTISFTSMAGYSAPIFWVALLMIMVFS--LHFEM 139
Cdd:PRK15133 122 SASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAggSYFDL 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 140 FPVGG----RYDLLYEIEHVTGFamidaffaegryrahalqsvIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIR 215
Cdd:PRK15133 202 FPLRGlvsaNFDSLPWYQKITDY--------------------LWHITLPVLATVIGGFAALTMLTKNSFLDEIRKQYVV 261

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 216 AARIKGLSTREIVTQHVLRNAIPPIIPKVGVQLSSM-LTLAIITESIFNWPGIGRWLLDALSNQDYvSIQAGVIVVATLV 294
Cdd:PRK15133 262 TARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMfFTGSLLIEVMFSLNGLGLLGYEATVSRDY-PVMFGTLYIFTLI 340

                        250
                 ....*....|....*..
gi 515650673 295 -LTANILSDLLGAMVNP 310
Cdd:PRK15133 341 gLLLNIVSDISYTLVDP 357
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 73-294 8.59e-14

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 68.84  E-value: 8.59e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  73 FPATLELCFFAFVLALFIGIPFGTIAGMRQGKfVDTTISFTSMAGYSAPIFWVALLMIMVFSLHFEMfpvggrydllyei 152
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK-LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGW------------- 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 153 ehvtgfamidaffaegryrahalqSVIEHMALPCLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHV 232
Cdd:cd06261   67 ------------------------GILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRII 122

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515650673 233 LRNAIPPIIPKVGVQLSSMLTLAIITESIFN----WPGIGRWLLDALSNQDYVSIQAGVIVVATLV 294
Cdd:cd06261  123 LPLALPPILTGLVLAFARALGEFALVSFLGGgeapGPGTGLLLIFAILFPGDLGVAAAVALILLLL 188
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 76-260 1.19e-12

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 67.06  E-value: 1.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673  76 TLELCFFAFVLALFIGIPFGTIAGMRqGKFVDTTISFTSMAGYSAPIFWVALLMIMVFslhfemfpvGGRydllyeiehv 155
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAGYF-GGWVDAVLMRLVDVLLAFPSLLLAIALVAVL---------GPG---------- 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 156 tgfamidaffaegryrahaLQSVIehmalpcLVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRN 235
Cdd:COG1173  141 -------------------LLNVI-------LALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPN 194

                        170       180
                 ....*....|....*....|....*
gi 515650673 236 AIPPIIpkvgVQLSSMLTLAIITES 260
Cdd:COG1173  195 VLPPLI----VQATLGIASAILAEA 215
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
187-268 7.28e-05

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 43.65  E-value: 7.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 187 LVLALAPTTQVIRLMRASVAEVMTQNYIRAARIKGLSTREIVTQHVLRNAIPPIIpkvgVQLSSMLTLAIITESIFNWPG 266
Cdd:PRK09881 161 LAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLI----VQASLDIGSAILMAATLGFIG 236


                 ..
gi 515650673 267 IG 268
Cdd:PRK09881 237 LG 238
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 211-310 4.08e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 38.21  E-value: 4.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515650673 211 QNYIRAARIKGLSTREIVTQHVLRNAIPPIIPKVGVQLSSMLTLAIITESIFNWPGIGRWLLDALSNQDYVSIQAGVIVV 290
Cdd:COG0600  153 PELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFAAILVI 232

                         90       100
                 ....*....|....*....|
gi 515650673 291 ATLVLTANILSDLLGAMVNP 310
Cdd:COG0600  233 GLLGLLLDLLLRLLERRLLR 252
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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