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Conserved domains on  [gi|515659248|ref|WP_017091848|]
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MULTISPECIES: BCCT family transporter [Vibrio]

Protein Classification

BCCT family transporter( domain architecture ID 10488420)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport

Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
37-520 1.09e-166

BCCT, betaine/carnitine/choline family transporter;


:

Pssm-ID: 460420  Cd Length: 485  Bit Score: 480.88  E-value: 1.09e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248   37 VFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFWQVLLLLNFIIGLVLALGRTGHVRLGT-LALPEMTTFKW 115
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGdDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  116 MSIVLCTLLAGGGVFWAAAEPIAHFVSAPPLyGNADPQAMAFNALSQSFMHWGFLAWAILGgLSSIVLMHLHYDKGLPLK 195
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSPPPG-GEPGTPEAAQQAMAYTFFHWGLHAWAIYA-LVALALAYFAYRKGLPLL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  196 PRTLLYPVLGDKaINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIVFAIAMYTLSALSG 275
Cdd:pfam02028 159 ISSALYPLLGDR-IDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  276 VNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMALYR----QDTAWLGGWTVFFWGWFLGYGP 351
Cdd:pfam02028 238 LDKGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTdpfgDTGGWLGGWTIFYWAWWIAWAP 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  352 MMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELENPGVISSAfEGFNLPAVLLAITAQLPFPTLIAI 431
Cdd:pfam02028 318 FVGMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLADA-VEAGPPAALFALLEQLPLGTILSV 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  432 LFLILTTTFIVTTGDSMTYTISVVMT-GTTEPNAAVRTFWGIIMGAVAIALISmgSGGISALQSFIVITAVPVSFILLPC 510
Cdd:pfam02028 397 LALLLIIIFFVTSADSGTLVIAMLSSgGDLNPPRWQRVFWGVLLGAVAAVLLL--AGGLEALQSASIIAALPFSFILLLM 474
                         490
                  ....*....|
gi 515659248  511 LWHAPKIAKQ 520
Cdd:pfam02028 475 CISLFKALRE 484
 
Name Accession Description Interval E-value
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
37-520 1.09e-166

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 480.88  E-value: 1.09e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248   37 VFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFWQVLLLLNFIIGLVLALGRTGHVRLGT-LALPEMTTFKW 115
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGdDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  116 MSIVLCTLLAGGGVFWAAAEPIAHFVSAPPLyGNADPQAMAFNALSQSFMHWGFLAWAILGgLSSIVLMHLHYDKGLPLK 195
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSPPPG-GEPGTPEAAQQAMAYTFFHWGLHAWAIYA-LVALALAYFAYRKGLPLL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  196 PRTLLYPVLGDKaINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIVFAIAMYTLSALSG 275
Cdd:pfam02028 159 ISSALYPLLGDR-IDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  276 VNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMALYR----QDTAWLGGWTVFFWGWFLGYGP 351
Cdd:pfam02028 238 LDKGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTdpfgDTGGWLGGWTIFYWAWWIAWAP 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  352 MMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELENPGVISSAfEGFNLPAVLLAITAQLPFPTLIAI 431
Cdd:pfam02028 318 FVGMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLADA-VEAGPPAALFALLEQLPLGTILSV 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  432 LFLILTTTFIVTTGDSMTYTISVVMT-GTTEPNAAVRTFWGIIMGAVAIALISmgSGGISALQSFIVITAVPVSFILLPC 510
Cdd:pfam02028 397 LALLLIIIFFVTSADSGTLVIAMLSSgGDLNPPRWQRVFWGVLLGAVAAVLLL--AGGLEALQSASIIAALPFSFILLLM 474
                         490
                  ....*....|
gi 515659248  511 LWHAPKIAKQ 520
Cdd:pfam02028 475 CISLFKALRE 484
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
28-520 5.90e-166

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 480.03  E-value: 5.90e-166
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  28 GEKLELGNPVFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFWQVLLLLNFIIGLVLALGRTGHVRLGTL-A 106
Cdd:COG1292    8 KFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDdA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 107 LPEMTTFKWMSIVLCTLLAGGGVFWAAAEPIAHFVSAPPLYGNADPQAMAFnALSQSFMHWGFLAWAILGgLSSIVLMHL 186
Cdd:COG1292   88 KPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGVEPGSPEAARW-AMAYTFFHWGLHAWAIYA-LVGLALAYF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 187 HYDKGLPLKPRTLLYPVLGDKaINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIVFAIA 266
Cdd:COG1292  166 AYRRGLPLTISSALYPLLGDR-IYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVITA 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 267 MYTLSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMALYR---QDTAWLGGWTVFFW 343
Cdd:COG1292  245 LFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTdayGDTGWLGGWTVFYW 324
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 344 GWFLGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELENPGVISSAFEGfNLPAVLLAITAQL 423
Cdd:COG1292  325 AWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAA-GVEAALFALLEQL 403
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 424 PFPTLIAILFLILTTTFIVTTGDSMTYTISVVMT-GTTEPNAAVRTFWGIIMGAVAIALISmgSGGISALQSFIVITAVP 502
Cdd:COG1292  404 PLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSgGDEEPPRWQRIFWGVLIGLVAAVLLL--AGGLSALQTASIITALP 481
                        490
                 ....*....|....*...
gi 515659248 503 VSFILLPCLWHAPKIAKQ 520
Cdd:COG1292  482 FSFVLLLMCVSLVKALRE 499
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
78-508 1.04e-91

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 287.71  E-value: 1.04e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248   78 WQVLLLLNFIigLVLALGRTGHVRLG-TLALPEMTTFKWMSIVLCTLLAGGGVFWAAAEPIAHFVSAPPLYGNADPQAMA 156
Cdd:TIGR00842   6 LTVTLFLGFV--LYIAFSRYGKIRLGrDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTTAQE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  157 FnALSQSFMHWGFLAWAILGgLSSIVLMHLHYDKGLPLKPRTLLYPVLGDKaINSWIGNVVDACSIVAVAAGTIGPIGFL 236
Cdd:TIGR00842  84 Q-ALAYTLFHWGIHPWAIYA-LVGLALAYFHFRKGLPLRLSSALVPLLGEK-VNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  237 GLQISYALSELFGISDSFATQSVVIVFAIAMYTLSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMG 316
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  317 EMVDNFIPMALYR----QDTAWLGGWTVFFWGWFLGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSG 392
Cdd:TIGR00842 241 NYLQNFPQMSFRTdpddGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  393 LAFELENPGVISSAFEGFNLPAVLLAITAQLPFPTLIAILFLILTTTFIVTTGDSMTYTISVVMTGT----TEPNAAVRT 468
Cdd:TIGR00842 321 LLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlgEEPPKWVRV 400
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 515659248  469 FWGIIMGAVAIALISMGsGGISALQSFIVITAVPVSFILL 508
Cdd:TIGR00842 401 FWAVAIGLIALVLLFSG-GSLAALQTTTIIAALPFSFVML 439
PRK09928 PRK09928
choline transport protein BetT; Provisional
29-508 1.12e-76

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 254.62  E-value: 1.12e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  29 EKLELGNPVFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFW--QVLLLLNFIIGLvlALGRTGHVRLG-TL 105
Cdd:PRK09928  11 EKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYllAATLYIVFVIFI--ACSRFGSIKLGpEQ 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 106 ALPEMTTFKWMSIVLCtllAGGGV---FWAAAEPIAHFVSAPPlyGNADPQAMAFNALSQSFMHWGFLAWAILGgLSSIV 182
Cdd:PRK09928  89 SKPEFSLLSWAAMLFA---AGIGIdlmFFSVAEPVTQYMQPPE--GAGQTIEAARQAMVWTLFHYGLTGWSMYA-LMGMA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 183 LMHLHYDKGLPLKPRTLLYPVLGdKAINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIV 262
Cdd:PRK09928 163 LGYFSYRYNLPLTIRSALYPIFG-KRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIA 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 263 FAIAMYTLSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMAL----YRQDTAWLGGW 338
Cdd:PRK09928 242 LSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLnsfaFDRPTEWMNNW 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 339 TVFFWGWFLGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELEnpGVISSAFEGFNLPAV-LL 417
Cdd:PRK09928 322 TLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH--GNAAFAEEAMAHPERgFY 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 418 AITAQLPFPTLIAILFLILTTTFIVTTGDSMTYTISVVMTGTTEPNAA----VRTFWGIIMGAVAIALISmgSGGISALQ 493
Cdd:PRK09928 400 SLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDapnwLRVFWSVAIGLLTLGMLM--TNGISALQ 477
                        490
                 ....*....|....*
gi 515659248 494 SFIVITAVPVSFILL 508
Cdd:PRK09928 478 NTTVIMGLPFSFVIF 492
 
Name Accession Description Interval E-value
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
37-520 1.09e-166

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 480.88  E-value: 1.09e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248   37 VFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFWQVLLLLNFIIGLVLALGRTGHVRLGT-LALPEMTTFKW 115
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGdDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  116 MSIVLCTLLAGGGVFWAAAEPIAHFVSAPPLyGNADPQAMAFNALSQSFMHWGFLAWAILGgLSSIVLMHLHYDKGLPLK 195
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSPPPG-GEPGTPEAAQQAMAYTFFHWGLHAWAIYA-LVALALAYFAYRKGLPLL 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  196 PRTLLYPVLGDKaINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIVFAIAMYTLSALSG 275
Cdd:pfam02028 159 ISSALYPLLGDR-IDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSG 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  276 VNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMALYR----QDTAWLGGWTVFFWGWFLGYGP 351
Cdd:pfam02028 238 LDKGIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTdpfgDTGGWLGGWTIFYWAWWIAWAP 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  352 MMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELENPGVISSAfEGFNLPAVLLAITAQLPFPTLIAI 431
Cdd:pfam02028 318 FVGMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLADA-VEAGPPAALFALLEQLPLGTILSV 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  432 LFLILTTTFIVTTGDSMTYTISVVMT-GTTEPNAAVRTFWGIIMGAVAIALISmgSGGISALQSFIVITAVPVSFILLPC 510
Cdd:pfam02028 397 LALLLIIIFFVTSADSGTLVIAMLSSgGDLNPPRWQRVFWGVLLGAVAAVLLL--AGGLEALQSASIIAALPFSFILLLM 474
                         490
                  ....*....|
gi 515659248  511 LWHAPKIAKQ 520
Cdd:pfam02028 475 CISLFKALRE 484
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
28-520 5.90e-166

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 480.03  E-value: 5.90e-166
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  28 GEKLELGNPVFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFWQVLLLLNFIIGLVLALGRTGHVRLGTL-A 106
Cdd:COG1292    8 KFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKIRLGGDdA 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 107 LPEMTTFKWMSIVLCTLLAGGGVFWAAAEPIAHFVSAPPLYGNADPQAMAFnALSQSFMHWGFLAWAILGgLSSIVLMHL 186
Cdd:COG1292   88 KPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGVEPGSPEAARW-AMAYTFFHWGLHAWAIYA-LVGLALAYF 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 187 HYDKGLPLKPRTLLYPVLGDKaINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIVFAIA 266
Cdd:COG1292  166 AYRRGLPLTISSALYPLLGDR-IYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIAVITA 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 267 MYTLSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMALYR---QDTAWLGGWTVFFW 343
Cdd:COG1292  245 LFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTdayGDTGWLGGWTVFYW 324
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 344 GWFLGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELENPGVISSAFEGfNLPAVLLAITAQL 423
Cdd:COG1292  325 AWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAA-GVEAALFALLEQL 403
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 424 PFPTLIAILFLILTTTFIVTTGDSMTYTISVVMT-GTTEPNAAVRTFWGIIMGAVAIALISmgSGGISALQSFIVITAVP 502
Cdd:COG1292  404 PLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSgGDEEPPRWQRIFWGVLIGLVAAVLLL--AGGLSALQTASIITALP 481
                        490
                 ....*....|....*...
gi 515659248 503 VSFILLPCLWHAPKIAKQ 520
Cdd:COG1292  482 FSFVLLLMCVSLVKALRE 499
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
78-508 1.04e-91

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 287.71  E-value: 1.04e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248   78 WQVLLLLNFIigLVLALGRTGHVRLG-TLALPEMTTFKWMSIVLCTLLAGGGVFWAAAEPIAHFVSAPPLYGNADPQAMA 156
Cdd:TIGR00842   6 LTVTLFLGFV--LYIAFSRYGKIRLGrDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTTAQE 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  157 FnALSQSFMHWGFLAWAILGgLSSIVLMHLHYDKGLPLKPRTLLYPVLGDKaINSWIGNVVDACSIVAVAAGTIGPIGFL 236
Cdd:TIGR00842  84 Q-ALAYTLFHWGIHPWAIYA-LVGLALAYFHFRKGLPLRLSSALVPLLGEK-VNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  237 GLQISYALSELFGISDSFATQSVVIVFAIAMYTLSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMG 316
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  317 EMVDNFIPMALYR----QDTAWLGGWTVFFWGWFLGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSG 392
Cdd:TIGR00842 241 NYLQNFPQMSFRTdpddGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  393 LAFELENPGVISSAFEGFNLPAVLLAITAQLPFPTLIAILFLILTTTFIVTTGDSMTYTISVVMTGT----TEPNAAVRT 468
Cdd:TIGR00842 321 LLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlgEEPPKWVRV 400
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 515659248  469 FWGIIMGAVAIALISMGsGGISALQSFIVITAVPVSFILL 508
Cdd:TIGR00842 401 FWAVAIGLIALVLLFSG-GSLAALQTTTIIAALPFSFVML 439
PRK09928 PRK09928
choline transport protein BetT; Provisional
29-508 1.12e-76

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 254.62  E-value: 1.12e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  29 EKLELGNPVFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFW--QVLLLLNFIIGLvlALGRTGHVRLG-TL 105
Cdd:PRK09928  11 EKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYllAATLYIVFVIFI--ACSRFGSIKLGpEQ 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 106 ALPEMTTFKWMSIVLCtllAGGGV---FWAAAEPIAHFVSAPPlyGNADPQAMAFNALSQSFMHWGFLAWAILGgLSSIV 182
Cdd:PRK09928  89 SKPEFSLLSWAAMLFA---AGIGIdlmFFSVAEPVTQYMQPPE--GAGQTIEAARQAMVWTLFHYGLTGWSMYA-LMGMA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 183 LMHLHYDKGLPLKPRTLLYPVLGdKAINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIV 262
Cdd:PRK09928 163 LGYFSYRYNLPLTIRSALYPIFG-KRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIA 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 263 FAIAMYTLSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMAL----YRQDTAWLGGW 338
Cdd:PRK09928 242 LSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLnsfaFDRPTEWMNNW 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 339 TVFFWGWFLGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELEnpGVISSAFEGFNLPAV-LL 417
Cdd:PRK09928 322 TLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH--GNAAFAEEAMAHPERgFY 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 418 AITAQLPFPTLIAILFLILTTTFIVTTGDSMTYTISVVMTGTTEPNAA----VRTFWGIIMGAVAIALISmgSGGISALQ 493
Cdd:PRK09928 400 SLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDapnwLRVFWSVAIGLLTLGMLM--TNGISALQ 477
                        490
                 ....*....|....*
gi 515659248 494 SFIVITAVPVSFILL 508
Cdd:PRK09928 478 NTTVIMGLPFSFVIF 492
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
30-506 1.78e-53

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 188.79  E-value: 1.78e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  30 KLELGNPVFWLSGSFLTLFVVLAFTNTSVLSELVNIGFSYSTKWFGAFWQVLLLLNFIIGLVLALGRTGHVRLGTLAlPE 109
Cdd:PRK03356   7 KTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDEK-PE 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 110 MTTFKWMSIVLCTLLAGGGVFWAAAEpIAHFVSAPPLYGNADPQAMAFNALSQSFMHWGFLAWAILGGLSSIVLMHLHYD 189
Cdd:PRK03356  86 FSTASWIFMMFASCTSAAVLFWGSIE-IYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFFFVR 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 190 KGLPLKPRTLLYPVLGDKAINSWIGNVVDACSIVAVAAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIVFAIAMYT 269
Cdd:PRK03356 165 KMDVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNA 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 270 LSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTSFIIDGYLQGMGEMVDNFIPMALYRQ---DTAWLGGWTVFFWGWF 346
Cdd:PRK03356 245 ICVACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDpigKGGFPQGWTVFYWAWW 324
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 347 LGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTCFWFSIVGGSGLAFELENPGVISSAFEGFNLPAVLLAITAQLPFP 426
Cdd:PRK03356 325 VIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVARAIIETWAALPLS 404
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 427 TLIAILFLILTTTFIVTTGDSMTYTISVV----MTGTTEPNAAVRTFWGIIMGAVAIALISMgsGGISALQSFIVITAVP 502
Cdd:PRK03356 405 TATMWGFFILCFIATVTLINACSYTLAMStcreVRDGEEPPLLVRIGWSILVGIIGIVLLAL--GGLKPIQTAIIAGGCP 482

                 ....
gi 515659248 503 VSFI 506
Cdd:PRK03356 483 LFFV 486
PRK09950 PRK09950
putative transporter; Provisional
67-520 1.49e-51

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 183.45  E-value: 1.49e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248  67 FSYSTKWFGAFWQVLLLLNFIIGLVLALGRTGHVRLGTlALPEMTTFKWMSIVLCTLLAGGGVFWAAAEpIAHFVSAPPL 146
Cdd:PRK09950  42 FQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLGE-GKPEYSTLSWLFMFICAGLGSSTLYWGVME-WAYYYQTPGL 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 147 -YGNADPQAMAFnALSQSFMHWGFLAWAILGGLSSIVLMHLHYDKGLPLKPRTLLYPVLGDKAINSWiGNVVDACSIVAV 225
Cdd:PRK09950 120 nIAPRSPKALEY-SVSYSFFHWGISAWATYALASLIMAYHFHVRKNKGLSLSGIIAAITGVKPQGPW-GRLVDLMFLIAT 197
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 226 AAGTIGPIGFLGLQISYALSELFGISDSFATQSVVIVFAIAMYTLSALSGVNKGIQLVSRYNIILSVCLIGYILLVGPTS 305
Cdd:PRK09950 198 VGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFCLSSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTE 277
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 306 FIIDGYLQGMGEMVDNFIPMALYRQ---DTAWLGGWTVFFWGWFLGYGPMMAIFIARISRGRTIRQMIVSISIVAPLVTC 382
Cdd:PRK09950 278 FITNNIINSIGLTTQNFLQMSLFTDpmgDGSFTRNWTVFYWLWWISYTPGVAMFVTRVSRGRKIKEVIWGLILGSSVGCW 357
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515659248 383 FWFSIvggsglafeLENPGVISSAFEGFNLPAVLLAIT---------AQLPFPTLIAILFLILTTTFIVTTGDSMTYTIS 453
Cdd:PRK09950 358 FFFGV---------LESYAIHQFINGVINVPQILNTLGgetavqqllSSLPAGKLFLAAYLGIMIIFLASHMDAVAYTMA 428
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515659248 454 VVMTGT----TEPNAAVRTFWGIIMGAVAIALISMGSgGISALQSFIVITAVPVSFILLPCLWHAPKIAKQ 520
Cdd:PRK09950 429 ATSTRNlregDDPDRGLRLFWCVVITLIPLSILFTGA-SLDTMKTTVVLTALPFLVILLIKVYGFIRWLKQ 498
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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