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Conserved domains on  [gi|515674917|ref|WP_017107517|]
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MULTISPECIES: chromosomal replication initiator protein DnaA [Vibrio]

Protein Classification

chromosomal replication initiator protein DnaA( domain architecture ID 11489097)

chromosomal replication initiator protein DnaA plays a key role in the initiation and regulation of chromosomal replication

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
21-471 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 683.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917   21 EFSMWVRPLQA-ELNGNTLTLFAPNRFVLDWVRDKYLNSINRLLQEYCGNDIpHLHFEIGSKRVTAPKSETVAPARTRTA 99
Cdd:TIGR00362  16 EYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEI-EIEFTVGEDEEELEPNSKKPEPAPPEA 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  100 AdvaaessapaqlqarkpvhniwrdeepvaVDLNHRSNVNPKHKFNNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGG 179
Cdd:TIGR00362  95 P-----------------------------APPSSASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGG 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  180 TGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHT 259
Cdd:TIGR00362 146 VGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHT 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  260 FNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNV 339
Cdd:TIGR00362 226 FNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNV 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  340 RELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMAL 419
Cdd:TIGR00362 306 RELEGALNRLLAYASLTGKPITLELAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYL 385
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 515674917  420 AKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYSNLIRTL 471
Cdd:TIGR00362 386 AKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
21-471 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 683.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917   21 EFSMWVRPLQA-ELNGNTLTLFAPNRFVLDWVRDKYLNSINRLLQEYCGNDIpHLHFEIGSKRVTAPKSETVAPARTRTA 99
Cdd:TIGR00362  16 EYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEI-EIEFTVGEDEEELEPNSKKPEPAPPEA 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  100 AdvaaessapaqlqarkpvhniwrdeepvaVDLNHRSNVNPKHKFNNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGG 179
Cdd:TIGR00362  95 P-----------------------------APPSSASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGG 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  180 TGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHT 259
Cdd:TIGR00362 146 VGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHT 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  260 FNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNV 339
Cdd:TIGR00362 226 FNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNV 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  340 RELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMAL 419
Cdd:TIGR00362 306 RELEGALNRLLAYASLTGKPITLELAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYL 385
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 515674917  420 AKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYSNLIRTL 471
Cdd:TIGR00362 386 AKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
dnaA PRK00149
chromosomal replication initiator protein DnaA;
1-473 0e+00

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 674.93  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917   1 MSSSLWLQCLQQLQEELPATEFSMWVRPLQ-AELNGNTLTLFAPNRFVLDWVRDKYLNSINRLLQeycgndiphlhfeig 79
Cdd:PRK00149   1 NLQSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ--------------- 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  80 skrvtapksetvapartrtaadvaaessapaqlqarkpvhniwrdeepvavdlnhrsnVNPKHKFNNFVEGKSNQLGLAA 159
Cdd:PRK00149  66 ----------------------------------------------------------LNPKYTFDNFVVGKSNRLAHAA 87
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 160 ARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALL 239
Cdd:PRK00149  88 ALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLL 167
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 240 IDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDH 319
Cdd:PRK00149 168 IDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPPKELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEE 247
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 320 QIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVAD 399
Cdd:PRK00149 248 GIDLPDEVLEFIAKNITSNVRELEGALNRLIAYASLTGKPITLELAKEALKDLLAAQKKKITIENIQKVVAEYYNIKVSD 327
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515674917 400 LLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYSNLIRTLSS 473
Cdd:PRK00149 328 LKSKSRTRNIARPRQIAMYLAKELTDLSLPEIGRAFGGRDHTTVLHAVRKIEKLLEEDPELKEDVEELKRKLKS 401
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
139-440 0e+00

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 545.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 139 NPKHKFNNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVK 218
Cdd:COG0593    2 NPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFIN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 219 ALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTV 298
Cdd:COG0593   82 AIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLVV 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 299 AIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEK 378
Cdd:COG0593  162 DIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDLLRAQKK 241
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515674917 379 LVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDH 440
Cdd:COG0593  242 EITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
Bac_DnaA pfam00308
Bacterial dnaA protein;
139-356 1.75e-124

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 361.26  E-value: 1.75e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  139 NPKHKFNNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVK 218
Cdd:pfam00308   2 NPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFVD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  219 ALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTV 298
Cdd:pfam00308  82 AIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLVT 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 515674917  299 AIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFT 356
Cdd:pfam00308 162 DIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSLN 219
Bac_DnaA_C cd06571
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ...
382-471 5.76e-42

C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.


Pssm-ID: 119330 [Multi-domain]  Cd Length: 90  Bit Score: 144.19  E-value: 5.76e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 382 IDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIK 461
Cdd:cd06571    1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
                         90
                 ....*....|
gi 515674917 462 EDYSNLIRTL 471
Cdd:cd06571   81 EDVEELEKKL 90
Bac_DnaA_C smart00760
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
381-449 2.23e-37

Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.


Pssm-ID: 197863 [Multi-domain]  Cd Length: 69  Bit Score: 131.09  E-value: 2.23e-37
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515674917   381 TIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRK 449
Cdd:smart00760   1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
 
Name Accession Description Interval E-value
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
21-471 0e+00

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 683.87  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917   21 EFSMWVRPLQA-ELNGNTLTLFAPNRFVLDWVRDKYLNSINRLLQEYCGNDIpHLHFEIGSKRVTAPKSETVAPARTRTA 99
Cdd:TIGR00362  16 EYNTWFKPLKLlSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEI-EIEFTVGEDEEELEPNSKKPEPAPPEA 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  100 AdvaaessapaqlqarkpvhniwrdeepvaVDLNHRSNVNPKHKFNNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGG 179
Cdd:TIGR00362  95 P-----------------------------APPSSASGLNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGG 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  180 TGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHT 259
Cdd:TIGR00362 146 VGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRNNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHT 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  260 FNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNV 339
Cdd:TIGR00362 226 FNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFIAKNITSNV 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  340 RELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMAL 419
Cdd:TIGR00362 306 RELEGALNRLLAYASLTGKPITLELAKEALKDLLRAQKKEITIENIQKVVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYL 385
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|..
gi 515674917  420 AKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYSNLIRTL 471
Cdd:TIGR00362 386 AKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEELKRKL 437
dnaA PRK00149
chromosomal replication initiator protein DnaA;
1-473 0e+00

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 674.93  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917   1 MSSSLWLQCLQQLQEELPATEFSMWVRPLQ-AELNGNTLTLFAPNRFVLDWVRDKYLNSINRLLQeycgndiphlhfeig 79
Cdd:PRK00149   1 NLQSLWEKVLERLKDELSEQEYETWIKPLKaLSLEDNTLTLYVPNRFVKDWIEKNYLDLIEEALQ--------------- 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  80 skrvtapksetvapartrtaadvaaessapaqlqarkpvhniwrdeepvavdlnhrsnVNPKHKFNNFVEGKSNQLGLAA 159
Cdd:PRK00149  66 ----------------------------------------------------------LNPKYTFDNFVVGKSNRLAHAA 87
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 160 ARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALL 239
Cdd:PRK00149  88 ALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFVNALRNNTMEEFKEKYRSVDVLL 167
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 240 IDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDH 319
Cdd:PRK00149 168 IDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPPKELPGLEERLRSRFEWGLTVDIEPPDLETRIAILKKKAEEE 247
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 320 QIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVAD 399
Cdd:PRK00149 248 GIDLPDEVLEFIAKNITSNVRELEGALNRLIAYASLTGKPITLELAKEALKDLLAAQKKKITIENIQKVVAEYYNIKVSD 327
                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515674917 400 LLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYSNLIRTLSS 473
Cdd:PRK00149 328 LKSKSRTRNIARPRQIAMYLAKELTDLSLPEIGRAFGGRDHTTVLHAVRKIEKLLEEDPELKEDVEELKRKLKS 401
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
139-440 0e+00

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 545.94  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 139 NPKHKFNNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVK 218
Cdd:COG0593    2 NPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFIN 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 219 ALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTV 298
Cdd:COG0593   82 AIRNNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGLVV 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 299 AIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEK 378
Cdd:COG0593  162 DIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDLLRAQKK 241
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515674917 379 LVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDH 440
Cdd:COG0593  242 EITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
Bac_DnaA pfam00308
Bacterial dnaA protein;
139-356 1.75e-124

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 361.26  E-value: 1.75e-124
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  139 NPKHKFNNFVEGKSNQLGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVK 218
Cdd:pfam00308   2 NPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFVD 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  219 ALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTV 298
Cdd:pfam00308  82 AIRDNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWGLVT 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 515674917  299 AIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFT 356
Cdd:pfam00308 162 DIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSLN 219
dnaA PRK14086
chromosomal replication initiator protein DnaA;
86-460 3.54e-116

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 354.13  E-value: 3.54e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  86 PKSETVAPARTRTAADVAAESSAPAQLQARKPVHNIWRDEEPVAVDLNHRSNVNPKHKFNNFVEGKSNQLGLAAARQVSD 165
Cdd:PRK14086 229 PEPPPGAGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPGEPTARLNPKYTFDTFVIGASNRFAHAAAVAVAE 308
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 166 NPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQF 245
Cdd:PRK14086 309 APAKAYNPLFIYGESGLGKTHLLHAIGHYARRLYPGTRVRYVSSEEFTNEFINSIRDGKGDSFRRRYREMDILLVDDIQF 388
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 246 FANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHQIHLAD 325
Cdd:PRK14086 389 LEDKESTQEEFFHTFNTLHNANKQIVLSSDRPPKQLVTLEDRLRNRFEWGLITDVQPPELETRIAILRKKAVQEQLNAPP 468
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 326 EVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKL-VTIDNIQKTVAEYYKIKVADLLSKR 404
Cdd:PRK14086 469 EVLEFIASRISRNIRELEGALIRVTAFASLNRQPVDLGLTEIVLRDLIPEDSAPeITAAAIMAATADYFGLTVEDLCGTS 548
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 515674917 405 RSRSVARPRQLAMALAKELTNHSLPEIGDAFgGRDHTTVLHACRKIAQLREESHDI 460
Cdd:PRK14086 549 RSRVLVTARQIAMYLCRELTDLSLPKIGQQF-GRDHTTVMHADRKIRALMAERRSI 603
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
125-473 1.73e-74

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 240.89  E-value: 1.73e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 125 EEPVAVDLNHRSNVNPKHKFNNFVEGKSN----QLGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIvdNKP 200
Cdd:PRK12422  91 QEKTAYFTMKYGELDPLMTFANFLVTPENdlphRILQEFTKVSEQGKGFPFNPIYLFGPEGSGKTHLMQAAVHAL--RES 168
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 201 NAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNAL-LEGnQQIILTSDRYPK 279
Cdd:PRK12422 169 GGKILYVRSELFTEHLVSAIRSGEMQRFRQFYRNVDALFIEDIEVFSGKGATQEEFFHTFNSLhTEG-KLIVISSTCAPQ 247
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 280 EINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRV---IANANFT 356
Cdd:PRK12422 248 DLKAMEERLISRFEWGIAIPLHPLTKEGLRSFLERKAEALSIRIEETALDFLIEALSSNVKSLLHALTLLakrVAYKKLS 327
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 357 GRPITIDFVREALRDLLALQEKL-VTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAF 435
Cdd:PRK12422 328 HQLLYVDDIKALLHDVLEAAESVrLTPSKIIRAVAQYYGVSPESILGRSQSREYVLPRQVAMYLCRQKLSLSYVKIGDVF 407
                        330       340       350
                 ....*....|....*....|....*....|....*....
gi 515674917 436 gGRDHTTVLHACRKIAQ-LREESHDIKEDYSNLIRTLSS 473
Cdd:PRK12422 408 -SRDHSTVISSIRAISQkLEEDDRDISMAIQEITKRLSS 445
Bac_DnaA_C cd06571
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ...
382-471 5.76e-42

C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.


Pssm-ID: 119330 [Multi-domain]  Cd Length: 90  Bit Score: 144.19  E-value: 5.76e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 382 IDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIK 461
Cdd:cd06571    1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
                         90
                 ....*....|
gi 515674917 462 EDYSNLIRTL 471
Cdd:cd06571   81 EDVEELEKKL 90
Bac_DnaA_C pfam08299
Bacterial dnaA protein helix-turn-helix;
382-450 1.42e-39

Bacterial dnaA protein helix-turn-helix;


Pssm-ID: 462419 [Multi-domain]  Cd Length: 69  Bit Score: 137.15  E-value: 1.42e-39
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515674917  382 IDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKI 450
Cdd:pfam08299   1 IEKIIEAVAEYFGISPEDLKSKSRKREIALARQIAMYLARELTDLSLPEIGRAFGGRDHSTVIHACKKI 69
Bac_DnaA_C smart00760
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
381-449 2.23e-37

Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.


Pssm-ID: 197863 [Multi-domain]  Cd Length: 69  Bit Score: 131.09  E-value: 2.23e-37
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515674917   381 TIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRK 449
Cdd:smart00760   1 TIEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
144-370 3.56e-32

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 122.30  E-value: 3.56e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  144 FNNFVEGkSNQLGLAAARQVSDNPGTayNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAkvVYMHSERFVQDMVKALqnN 223
Cdd:TIGR03420  14 FDNFYAG-GNAELLAALRQLAAGKGD--RFLYLWGESGSGKSHLLQAACAAAEERGKSA--IYLPLAELAQADPEVL--E 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  224 AIEEFkryyrsvDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPP 303
Cdd:TIGR03420  87 GLEQA-------DLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLPPL 159
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515674917  304 ELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALR 370
Cdd:TIGR03420 160 SDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
153-296 1.33e-18

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 82.58  E-value: 1.33e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 153 NQLGLAAARQVSDNPgtAYNPLFLYGGTGLGKTHLLHAVGNAIVdnKPNAKVVYMHSERFVQDMVKALQ----NNAIEEF 228
Cdd:cd00009    3 QEEAIEALREALELP--PPKNLLLYGPPGTGKTTLARAIANELF--RPGAPFLYLNASDLLEGLVVAELfghfLVRLLFE 78
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515674917 229 KRYYRSVDALLIDDIQFFANKERSQ-EEFFHTFNALLE--GNQQIILTSDR--YPKEINGVEDRLKSRFGWGL 296
Cdd:cd00009   79 LAEKAKPGVLFIDEIDSLSRGAQNAlLRVLETLNDLRIdrENVRVIGATNRplLGDLDRALYDRLDIRIVIPL 151
PRK08084 PRK08084
DnaA inactivator Hda;
144-370 7.26e-18

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 82.42  E-value: 7.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 144 FNNFVEGKSNQLgLAAARQVSDNPGTAYnpLFLYGGTGLGKTHLLHAVGNAIvdNKPNAKVVYMHSER---FVQDMVKAL 220
Cdd:PRK08084  21 FASFYPGDNDSL-LAALQNALRQEHSGY--IYLWSREGAGRSHLLHAACAEL--SQRGRAVGYVPLDKrawFVPEVLEGM 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 221 QnnaieefkryyrSVDALLIDDIQFFANKERSQEEFFHTFNALLE-GNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVA 299
Cdd:PRK08084  96 E------------QLSLVCIDNIECIAGDELWEMAIFDLYNRILEsGRTRLLITGDRPPRQLNLGLPDLASRLDWGQIYK 163
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515674917 300 IEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALR 370
Cdd:PRK08084 164 LQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILK 234
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
144-369 3.67e-15

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 74.63  E-value: 3.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 144 FNNFVEGKSNQLgLAAARQVSdnPGTAYNPLF-LYGGTGLGKTHLLHAVGNAIVDNKPNAkvVYmhserfvqdmvkaLQN 222
Cdd:PRK08903  17 FDNFVAGENAEL-VARLRELA--AGPVADRFFyLWGEAGSGRSHLLQALVADASYGGRNA--RY-------------LDA 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 223 NAIEEFKRYYRSVDALLIDDIQFFANKErsQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEP 302
Cdd:PRK08903  79 ASPLLAFDFDPEAELYAVDDVERLDDAQ--QIALFNLFNRVRAHGQGALLVAGPAAPLALPLREDLRTRLGWGLVYELKP 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515674917 303 PELETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREAL 369
Cdd:PRK08903 157 LSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPSLMALLDALDRYSLEQKRPVTLPLLREML 223
DnaA_N pfam11638
DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a ...
3-65 7.11e-11

DnaA N-terminal domain; This family of proteins represents the N-terminal domain of DnaA, a protein involved in the initiation of bacterial chromosomal replication. The structure of this domain is known. It is also found in three copies in some proteins. The exact function of this domain is uncertain but it has been suggested to play a role in oligomerization.


Pssm-ID: 463316 [Multi-domain]  Cd Length: 65  Bit Score: 57.68  E-value: 7.11e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515674917    3 SSLWLQCLQQLQEELPATEFSMWVRPLQAE--LNGNTLTLFAPNRFVLDWVRDKYLNSINRLLQE 65
Cdd:pfam11638   1 EELWERVLERLRKEVGEQTFNTWIKPLTLVdlDDGGSLTLSVPNRFVRDWVEEHYLDRILELWQE 65
PRK06030 PRK06030
hypothetical protein; Provisional
389-456 8.72e-11

hypothetical protein; Provisional


Pssm-ID: 180356  Cd Length: 124  Bit Score: 59.41  E-value: 8.72e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515674917 389 VAEYYKIKVADLLS-KRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGgRDHTTVLHACRKIAQLREE 456
Cdd:PRK06030  32 LALAFGVSGAEIASpLRGRREVSRIRQIAMYVAHVSLGWPMNEVALAFG-RDRTTVGHACHTVEDLRDD 99
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
174-274 1.00e-10

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 61.72  E-value: 1.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 174 LFLYGGTGLGKTHLLHAVGNAIVDNkpNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQ 253
Cdd:COG1484  102 LILLGPPGTGKTHLAIALGHEACRA--GYRVRFTTAPDLVNELKEARADGRLERLLKRLAKVDLLILDELGYLPLDAEGA 179
                         90       100
                 ....*....|....*....|.
gi 515674917 254 EEFFHTFNALLEgNQQIILTS 274
Cdd:COG1484  180 ELLFELISDRYE-RRSTIITS 199
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
172-292 3.21e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 52.76  E-value: 3.21e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917   172 NPLFLYGGTGLGKTHLLHAVGNAIvdNKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRY---------------YRSVD 236
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALAREL--GPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASgsgelrlrlalalarKLKPD 80
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515674917   237 ALLIDDIQFFANKERSQEEFFHTFNALL-----EGNQQIILTSDRYPKEIngvEDRLKSRF 292
Cdd:smart00382  81 VLILDEITSLLDAEQEALLLLLEELRLLlllksEKNLTVILTTNDEKDLG---PALLRRRF 138
PRK06835 PRK06835
DNA replication protein DnaC; Validated
174-292 4.05e-08

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 54.91  E-value: 4.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 174 LFLYGGTGLGKTHLLHAVGNAIVDNKpnAKVVYMHSERFVQDMVKA-LQNNAIEEFKR-YYRSVDALLIDDIQFFANKER 251
Cdd:PRK06835 186 LLFYGNTGTGKTFLSNCIAKELLDRG--KSVIYRTADELIEILREIrFNNDKELEEVYdLLINCDLLIIDDLGTEKITEF 263
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 515674917 252 SQEEFFHTFNA-LLEGNQQIILT-------SDRYPKEINGvedRLKSRF 292
Cdd:PRK06835 264 SKSELFNLINKrLLRQKKMIISTnlsleelLKTYSERISS---RLLGNF 309
PRK08939 PRK08939
primosomal protein DnaI; Reviewed
174-243 1.25e-06

primosomal protein DnaI; Reviewed


Pssm-ID: 236353 [Multi-domain]  Cd Length: 306  Bit Score: 50.25  E-value: 1.25e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 174 LFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYMHSerFVQDMVKALQNNAIEEFKRYYRSVDALLIDDI 243
Cdd:PRK08939 159 LYLYGDFGVGKSYLLAAIANELAKKGVSSTLLHFPE--FIRELKNSISDGSVKEKIDAVKEAPVLMLDDI 226
PRK06672 PRK06672
hypothetical protein; Validated
2-105 3.89e-05

hypothetical protein; Validated


Pssm-ID: 180654 [Multi-domain]  Cd Length: 341  Bit Score: 45.52  E-value: 3.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917   2 SSSLWLQCLQQLQEELPATEFSMWVRPLQAELNGNTLTLFAPNRFVLDWVRDKYLNSINRLLQEYCGNDIpHLHFEIgsk 81
Cdd:PRK06672 191 SKTIWNKIKDKMQLKISRPSYETWVKETTARINEDSLIIYFENEFQQEWVKKSYKDLISQIAKELTGNTY-EIQFEL--- 266
                         90       100
                 ....*....|....*....|....
gi 515674917  82 rvtapKSETVAPARTRTAADVAAE 105
Cdd:PRK06672 267 -----KSNTTSNNEKSTIKDITSE 285
PRK12377 PRK12377
putative replication protein; Provisional
81-243 5.21e-05

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 44.83  E-value: 5.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917  81 KRVTAPKSetVAPARTrtaadvAAESSAPAQLQARKPVHNIWRDEEPVAVD--LNhRSNVNPKHK---FNNF-VEGKSNQ 154
Cdd:PRK12377  14 RRLAPQGV--QPPFRT------VDEWREWQLAEGRKRSEEINRQNQQLRVEkiLN-RSGIQPLHRkcsFANYqVQNDGQR 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 155 LGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYmhserfVQDMVKALQN-----NAIEEFK 229
Cdd:PRK12377  85 YALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLLAKGRSVIVVT------VPDVMSRLHEsydngQSGEKFL 158
                        170
                 ....*....|....
gi 515674917 230 RYYRSVDALLIDDI 243
Cdd:PRK12377 159 QELCKVDLLVLDEI 172
PRK08116 PRK08116
hypothetical protein; Validated
143-291 4.17e-04

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 41.93  E-value: 4.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 143 KFNNF-VEGKSNQLGLAAARQV-------SDNPGtaynpLFLYGGTGLGKTHLLHAVGNAIVDNKpnAKVVYMHSERFVQ 214
Cdd:PRK08116  83 TFENFlFDKGSEKAYKIARKYVkkfeemkKENVG-----LLLWGSVGTGKTYLAACIANELIEKG--VPVIFVNFPQLLN 155
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 215 DMVKALQNNAIEEFKRYYRSV---DALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEI-NGVEDRLKS 290
Cdd:PRK08116 156 RIKSTYKSSGKEDENEIIRSLvnaDLLILDDLGAERDTEWAREKVYNIIDSRYRKGLPTIVTTNLSLEELkNQYGKRIYD 235

                 .
gi 515674917 291 R 291
Cdd:PRK08116 236 R 236
PRK09087 PRK09087
hypothetical protein; Validated
176-350 5.91e-04

hypothetical protein; Validated


Pssm-ID: 169652 [Multi-domain]  Cd Length: 226  Bit Score: 41.20  E-value: 5.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 176 LYGGTGLGKTHLlhavgNAIVDNKPNAkvVYMHSERFVQDMVKALQNNAIeefkryyrsvdalLIDDIQffaNKERSQEE 255
Cdd:PRK09087  49 LAGPVGSGKTHL-----ASIWREKSDA--LLIHPNEIGSDAANAAAEGPV-------------LIEDID---AGGFDETG 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 256 FFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKAEDHQIHLADEVAFFIAKRL 335
Cdd:PRK09087 106 LFHLINSVRQAGTSLLMTSRLWPSSWNVKLPDLKSRLKAATVVEIGEPDDALLSQVIFKLFADRQLYVDPHVVYYLVSRM 185
                        170
                 ....*....|....*
gi 515674917 336 RsnvRELEgALNRVI 350
Cdd:PRK09087 186 E---RSLF-AAQTIV 196
PRK06921 PRK06921
hypothetical protein; Provisional
144-300 1.06e-03

hypothetical protein; Provisional


Pssm-ID: 180750 [Multi-domain]  Cd Length: 266  Bit Score: 40.92  E-value: 1.06e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 144 FNNFV-EGKSNQLGLA---AARQVSDNP---GTAYNPLFLYGGTGLGKTHLLHAVGNAIVdNKPNAKVVYMhseRFVQDM 216
Cdd:PRK06921  83 FKNFKtEGKPQAIKDAyecAVEYVKDFEkiqESRKNSIALLGQPGSGKTHLLTAAANELM-RKKGVPVLYF---PFVEGF 158
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 217 VKaLQNN--AIEEFKRYYRSVDALLIDDIQFFANKERSQEEF-----FHTFNALLEGNQQIILTSDRYPKEINGVEDRLK 289
Cdd:PRK06921 159 GD-LKDDfdLLEAKLNRMKKVEVLFIDDLFKPVNGKPRATEWqieqmYSVLNYRYLNHKPILISSELTIDELLDIDEALG 237
                        170
                 ....*....|....
gi 515674917 290 SRF---GWGLTVAI 300
Cdd:PRK06921 238 SRIvemCKDYLVII 251
PRK06620 PRK06620
hypothetical protein; Validated
225-369 1.52e-03

hypothetical protein; Validated


Pssm-ID: 168630  Cd Length: 214  Bit Score: 39.83  E-value: 1.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 225 IEEFkryYRSVDALLIDDIQFFANKErsqeeFFHTFNALLEGNQQIILTSDRYPKeiNGVEDRLKSRFGWGLTVAIEPPE 304
Cdd:PRK06620  79 NEEI---LEKYNAFIIEDIENWQEPA-----LLHIFNIINEKQKYLLLTSSDKSR--NFTLPDLSSRIKSVLSILLNSPD 148
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515674917 305 LETRVAILMKKAEDHQIHLADEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREAL 369
Cdd:PRK06620 149 DELIKILIFKHFSISSVTISRQIIDFLLVNLPREYSKIIEILENINYFALISKRKITISLVKEVL 213
PRK07952 PRK07952
DNA replication protein DnaC; Validated
135-243 6.77e-03

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 38.21  E-value: 6.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515674917 135 RSNVNPKHK---FNNF-VEGKSNQLGLAAARQVSDNPGTAYNPLFLYGGTGLGKTHLLHAVGNAIVDNKPNAKVVYmhse 210
Cdd:PRK07952  59 RSGIRPLHQncsFENYrVECEGQMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIIT---- 134
                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 515674917 211 rfVQDMVKALQ------NNAIEEFKRYYRSVDALLIDDI 243
Cdd:PRK07952 135 --VADIMSAMKdtfsnsETSEEQLLNDLSNVDLLVIDEI 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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