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Conserved domains on  [gi|515742308|ref|WP_017174908|]
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MULTISPECIES: CPBP family intramembrane glutamic endopeptidase [Staphylococcus]

Protein Classification

CPBP family intramembrane glutamic endopeptidase( domain architecture ID 11441430)

CPBP (CAAX proteases and bacteriocin-processing enzymes) family intramembrane protease similar to Saccharomyces cerevisiae Rce1, a type II CAAX prenyl protease that processes all farnesylated and geranylgeranylated CAAX proteins. It is an integral membrane endoprotease that belongs to the glutamate IMPs, sharing a conserved sequence motif EExxxR

EC:  3.4.-.-
Gene Ontology:  GO:0004222|GO:0016020|GO:0070007|GO:0071586
PubMed:  24291792

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YdiL COG1266
Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, ...
 120-221 6.01e-12

Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440877 [Multi-domain]  Cd Length: 97  Bit Score: 61.35  E-value: 6.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742308 120 VFTIIVGHIFMAFFAEFGFRSYLQNIVESKVNTFFASIIVGLMYSIWTINTtygmqyaGYHFLYTFMFSMIVGELIRATK 199
Cdd:COG1266    5 LLFLLVVVILAPIAEELLFRGYLLGRLRRRFGPWLAILLSSLLFGLLHLPN-------LLGFLPAFLLGLVLGLLYLRTG 77

                         90       100
                 ....*....|....*....|..
gi 515742308 200 GrtIYIAMLFHAAMTFAQVFLF 221
Cdd:COG1266   78 S--LWVPILLHALNNLLALLLL 97
 
Name Accession Description Interval E-value
YdiL COG1266
Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, ...
 120-221 6.01e-12

Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440877 [Multi-domain]  Cd Length: 97  Bit Score: 61.35  E-value: 6.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742308 120 VFTIIVGHIFMAFFAEFGFRSYLQNIVESKVNTFFASIIVGLMYSIWTINTtygmqyaGYHFLYTFMFSMIVGELIRATK 199
Cdd:COG1266    5 LLFLLVVVILAPIAEELLFRGYLLGRLRRRFGPWLAILLSSLLFGLLHLPN-------LLGFLPAFLLGLVLGLLYLRTG 77

                         90       100
                 ....*....|....*....|..
gi 515742308 200 GrtIYIAMLFHAAMTFAQVFLF 221
Cdd:COG1266   78 S--LWVPILLHALNNLLALLLL 97
 
Name Accession Description Interval E-value
YdiL COG1266
Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, ...
 120-221 6.01e-12

Membrane protease YdiL, CAAX protease family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440877 [Multi-domain]  Cd Length: 97  Bit Score: 61.35  E-value: 6.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742308 120 VFTIIVGHIFMAFFAEFGFRSYLQNIVESKVNTFFASIIVGLMYSIWTINTtygmqyaGYHFLYTFMFSMIVGELIRATK 199
Cdd:COG1266    5 LLFLLVVVILAPIAEELLFRGYLLGRLRRRFGPWLAILLSSLLFGLLHLPN-------LLGFLPAFLLGLVLGLLYLRTG 77

                         90       100
                 ....*....|....*....|..
gi 515742308 200 GrtIYIAMLFHAAMTFAQVFLF 221
Cdd:COG1266   78 S--LWVPILLHALNNLLALLLL 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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