|
Name |
Accession |
Description |
Interval |
E-value |
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
1-380 |
0e+00 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 578.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLR-------QGYEYSRTANPTRASIESVIANLENGKHGFAFG 73
Cdd:COG0626 1 MGPATRAVHAGRDPDPQTGAVSPPIYLTSTFVFPSAEALAarfageeGGYIYSRYGNPTRRALEEALAALEGGEAALAFA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 74 SGMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVT 152
Cdd:COG0626 81 SGMAAISAVLLaLLKAGDHVVASDDLYGGTRRLLDKVLARFGIEVTFVDPTDLAAVEAAIRPNTKLVFLETPSNPTLEVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 153 DIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLG 232
Cdd:COG0626 161 DIAAIAAIAHAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVVGRDEELAERLRFLQNALGAVLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 233 PQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDT-EAAKQL 311
Cdd:COG0626 241 PFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYPGLPSHPGHELAKRQMSGFGGMLSFELKGGrEAARRF 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515742593 312 IRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:COG0626 321 LDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLEDVDDLIADLEQALAAL 389
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
1-378 |
0e+00 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 577.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDlRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAIS 80
Cdd:PRK07671 1 MRAKTKLIHGGIIGDPSTGAVSVPIYQVSTYKQEAVGK-HQGYEYSRTGNPTRAALEELIAVLEGGHAGFAFGSGMAAIT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 81 AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEI 160
Cdd:PRK07671 80 AVMMLFSSGDHVILTDDVYGGTYRVMTKVLNRFGIEHTFVDTSNLEEVEEAIRPNTKAIYVETPTNPLLKITDIKKISTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 161 AKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLI 240
Cdd:PRK07671 160 AKEKGLLTIVDNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGLVVVNSPELAEDLHFVQNSTGGILGPQDSWLLL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 241 RGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQLIRETHYFTL 320
Cdd:PRK07671 240 RGLKTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYPGLPSHPNHELAKEQANGFGGMISFDVGSEETANKVLERLQYFTL 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 515742593 321 AESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAID 378
Cdd:PRK07671 320 AESLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIEDGEDLIEDLAQALA 377
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
5-376 |
0e+00 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 524.87 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRqGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIM 84
Cdd:pfam01053 2 TLAVHAGQRPDPQTGAVSVPIYLTSTYVFDFAGEEG-GYDYSRSGNPTRDVLEERIAALEGGAAALAFSSGMAAITAAIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 85 -LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKE 163
Cdd:pfam01053 81 aLLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVTFVDTSDPEDLEAAIKPNTKAVYLETPTNPLLKVVDIEAIAKLAKK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 164 NQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGI 243
Cdd:pfam01053 161 HGILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNGEELGKELYFLQNATGAVLSPFDAWLLLRGL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 244 KTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDT-EAAKQLIRETHYFTLAE 322
Cdd:pfam01053 241 KTLGLRMEQHQENAQKVAEFLESHPKVEKVYYPGLPSHPGHELAKRQMKGFGGMLSFELKGGlEAAKKFLDNLKLFSLAV 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 515742593 323 SLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQA 376
Cdd:pfam01053 321 SLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDDLIADLKQA 374
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
19-378 |
1.80e-175 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 492.87 E-value: 1.80e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 19 GAVTTPIYQTSTYLQDDIGDLRQ-------GYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIM-LLDKGD 90
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAADlfalregGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAISTVLLaLLKAGD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 91 HLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKENQLISVV 170
Cdd:cd00614 81 HVVASDDLYGGTYRLFERLLPKLGIEVTFVDPDDPEALEAAIKPETKLVYVESPTNPTLKVVDIEAIAELAHEHGALLVV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 171 DNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGIKTLGLRM 250
Cdd:cd00614 161 DNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSGEALIQRLRFLRLALGTILSPFDAWLLLRGLKTLPLRM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 251 EQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDT-EAAKQLIRETHYFTLAESLGAVES 329
Cdd:cd00614 241 ERHSENALKVAEFLEKHPKVERVYYPGLPSHPQHELAKKQMSGYGGVFSFELKGGlEAAKKFLNALKLFSLAVSLGGVES 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 515742593 330 LISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAID 378
Cdd:cd00614 321 LVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
5-378 |
5.58e-172 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 484.92 E-value: 5.58e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVI- 83
Cdd:PRK07811 15 TRAIHAGYEPDPATGAVNPPIYASSTFAQDGVGGLRGGYEYARTGNPTRTALEEQLAALEGGAYGRAFSSGMAATDCLLr 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 84 MLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKE 163
Cdd:PRK07811 95 AVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVEYTPVDLSDLDAVRAAITPRTKLIWVETPTNPLLSITDIAALAELAHD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 164 NQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGI 243
Cdd:PRK07811 175 AGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVGGALVTNDEELDEAFAFLQNGAGAVPGPFDAYLTLRGL 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 244 KTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKD-TEAAKQLIRETHYFTLAE 322
Cdd:PRK07811 255 KTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYPGLPSHPGHEVAARQMRGFGGMVSVRLAGgEEAARDFCARTKVFTLAE 334
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515742593 323 SLGAVESLISVPALMTHAS-------IPADvrakegitdgLVRLSIGIEDTEDLVQDLKQAID 378
Cdd:PRK07811 335 SLGGVESLIEHPSAMTHAStagsqleVPDD----------LVRLSVGIEDVADLLADLEQALG 387
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
1-380 |
2.71e-170 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 480.16 E-value: 2.71e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDlRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAIS 80
Cdd:PRK06176 1 MRMQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGR-PKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIH 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 81 AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEI 160
Cdd:PRK06176 80 AVFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 161 AKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLI 240
Cdd:PRK06176 160 AKDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQ 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 241 RGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQLIRETHYFTL 320
Cdd:PRK06176 240 RGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYPGLPTHPNHELAKKQMRGFSGMLSFTLKNDSEAVAFVESLKLFIL 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 321 AESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:PRK06176 320 GESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKI 379
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
5-382 |
1.13e-167 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 473.87 E-value: 1.13e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQgYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIM 84
Cdd:PRK08064 9 TLLLHNQYKHDKQTGAVNVPIYHASTFHQFDFDTFGK-YDYSRSGNPTREALEDIIAELEGGTKGFAFASGMAAISTAFL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 85 LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKEN 164
Cdd:PRK08064 88 LLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHTFVDMTNLEEVAQNIKPNTKLFYVETPSNPLLKVTDIRGVVKLAKAI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 165 QLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGIK 244
Cdd:PRK08064 168 GCLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGLAVVKDEELAQKLYFLQNSFGAVLGVQDCWLVLRGLK 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 245 TLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQLIRETHYFTLAESL 324
Cdd:PRK08064 248 TLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFDIQQSQATSAGAVLSFTLQSEEAVRQFVSHVKLPVFAVSL 327
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 515742593 325 GAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTLNK 382
Cdd:PRK08064 328 GAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLIADFEQALSYVEE 385
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
4-377 |
4.06e-144 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 413.33 E-value: 4.06e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 4 KTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDlRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVI 83
Cdd:PRK08247 6 ETKLAQIGNRSDERTGTVNPPVYFSTAYRHEGIGE-STGFDYSRTGNPTRGVLEQAIADLEGGDQGFACSSGMAAIQLVM 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 84 MLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKE 163
Cdd:PRK08247 85 SLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFVYVNTASLKAIEQAITPNTKAIFIETPTNPLMQETDIAAIAKIAKK 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 164 NQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGI 243
Cdd:PRK08247 165 HGLLLIVDNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVAKGQELCERLAYYQNAAGAVLSPFDSWLLIRGM 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 244 KTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPsieshlnhdihiaqasGHTGVVAFEVKDTEAAKQLIRETHYFTLAES 323
Cdd:PRK08247 245 KTLALRMRQHEENAKAIAAFLNEQPGVTDVLYP----------------GRGGMLSFRLQDEEWVNPFLKSLKLITFAES 308
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 515742593 324 LGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:PRK08247 309 LGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENVEDLIADLKQAF 362
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
5-377 |
6.75e-137 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 395.35 E-value: 6.75e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFtGAVTTPIYQTSTYLQDDIGDLRQgYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIM 84
Cdd:TIGR01329 3 TLLVNTDNKNDPY-DASSMPIYQTATFKQPLAIENGP-YDYTRSGNPTRTALESLLAKLDKADRAFAFSSGMAALDVITR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 85 LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKEN 164
Cdd:TIGR01329 81 LLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVVHVDTTDLDKVKAALGPKTKLVLLESPTNPLQKIVDIRKISEMAHAQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 165 QLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGIK 244
Cdd:TIGR01329 161 NALVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVLAVKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGIK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 245 TLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQLIRETHYFTLAESL 324
Cdd:TIGR01329 241 TLAIRIEKQQENARAIAMFLSTHPRVKKVRYAGLPSHPGFHLHFSQAKGAGSVLSFETGSVALSKRLVEATKLFSITVSF 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 515742593 325 GAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:TIGR01329 321 GSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIEDVDDLISDLDIAF 373
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
5-382 |
1.41e-130 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 380.33 E-value: 1.41e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQD--DIGDLR-----QGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK06234 11 TKAIHGGHIGDKQFGSLATPIYQTSTFIFDsaEQGGRRfageeSGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVI-MLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:PRK06234 91 AISSSLwSALKAGDHVVASDTLYGCTFALLNHGLTRYGVEVTFVDTSNLEEVRNALKANTKVVYLETPANPTLKVTDIKA 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKEN--QLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGE-RLAFISNSTGGVLGP 233
Cdd:PRK06234 171 ISNIAHENnkECLVFVDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQvKLFGIKDMTGSVIGP 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 234 QDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK-DTEAAKQLI 312
Cdd:PRK06234 251 FEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYPGLESFEYYELAKKQMSLPGAMISFELKgGVEEGKVVM 330
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 313 RETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTLNK 382
Cdd:PRK06234 331 NNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALDLIVK 400
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
1-378 |
1.17e-124 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 365.89 E-value: 1.17e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDD---IGDL----RQGYEYSRTANPTRASIESVIANLENGKHGFAFG 73
Cdd:COG2873 6 YGFETLALHAGQEPDPTTGARAVPIYQTTSYVFDDaehAADLfalkEPGNIYTRIMNPTTDVLEKRIAALEGGVAALATA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 74 SGMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVT 152
Cdd:COG2873 86 SGQAAITLAILnLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIEVRFVDPDDPEAFEAAIDPNTKAIFGETIGNPALDVL 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 153 DIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATS-------------------- 212
Cdd:COG2873 166 DIEAIAEIAHEHGVPLIVDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTSIGGVIVDGgnfdwaangkfpeltepdps 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 213 ------NDELGErLAFIS-------NSTGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIE 279
Cdd:COG2873 246 yhglvyTEAFGN-AAFITkarvqllRDLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLEAHPKVAWVNYPGLP 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 280 SHLNHDihIAQ---ASGHTGVVAFEVK-DTEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDG 355
Cdd:COG2873 325 SHPYHE--LAQkylPKGAGGVLTFGLKgGREAGKKFIDSLKLFSHLANIGDAKSLVIHPASTTHSQLSEEEQAAAGVTPD 402
|
410 420
....*....|....*....|...
gi 515742593 356 LVRLSIGIEDTEDLVQDLKQAID 378
Cdd:COG2873 403 LIRLSVGIEDIDDIIADLDQALA 425
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
2-377 |
1.76e-124 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 364.12 E-value: 1.76e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 2 KKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQgYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISA 81
Cdd:TIGR02080 3 KQATIAVRSGLNSDTQYGCVVPPIYLSTTYNFTGFNEPRA-YDYSRSGNPTRDLLQQALAELEGGAGAVVTNTGMSAIHL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 82 V-IMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEI 160
Cdd:TIGR02080 82 VtTALLGPDDLLVAPHDCYGGTYRLLNALAKKGCFRVLFVDQGDEQALRAALAQKPKLVLIETPSNPLLRVVDIAKICHL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 161 AKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLI 240
Cdd:TIGR02080 162 AKAVGAVVVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVIAGAVIAKDPQVAEELAWWANNLGVTGGAFDSYLTL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 241 RGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAA-KQLIRETHYFT 319
Cdd:TIGR02080 242 RGLRTLVARMRLQQRNAQAIVEYLQTQPLVKKIYYPGLPDHPGHEIAARQQKGFGAMLSFELKGGEQTvRRFLGGLSLFT 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 515742593 320 LAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:TIGR02080 322 LAESLGGVESLIAHPATMTHAAMGPEARAEAGISDTLLRLSVGLEDADDLIADLEQGL 379
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
20-379 |
5.90e-124 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 365.51 E-value: 5.90e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 20 AVTTPIYQTSTYLQDDIgdLRQG-YEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIMLLDKGDHLILNSDV 98
Cdd:PLN02509 103 AMSTPLYQTATFKQPSA--IENGpYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDV 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 99 YGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKENQLISVVDNTFMTPY 178
Cdd:PLN02509 181 YGGSDRLLSQVVPRSGVVVKRVNTTNLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKIAEMAHAQGALVLVDNSIMSPV 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 179 YQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGIKTLGLRMEQINRNVE 258
Cdd:PLN02509 261 LSRPLELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENAR 340
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 259 GIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQLIRETHYFTLAESLGAVESLISVPALMT 338
Cdd:PLN02509 341 KIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSFITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMS 420
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 515742593 339 HASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDT 379
Cdd:PLN02509 421 HASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFRT 461
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
5-380 |
6.45e-123 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 360.36 E-value: 6.45e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDI---GDL----RQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:TIGR01328 6 TRAIHAGYPPKDQFGALTPPIYQTSTFVFDSCeqgGNRfagqESGYIYSRLGNPTVSNLEGRIAFLEGTEAAVATSSGMG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:TIGR01328 86 AIAATLLtILKAGDHLISDECLYGCTFALLEHALTKFGIQVDFINMAIPEEVKAHIKDNTKIVYFETPANPTMKLIDMER 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGE-RLAFISNSTGGVLGPQD 235
Cdd:TIGR01328 166 VCRDAHSQGVKVIVDNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICGKAELLQQiRMVGIKDMTGSVISPFD 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 236 SYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEA-AKQLIRE 314
Cdd:TIGR01328 246 AWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGHDIAAKQMRMGGGMITFELKGGFAgAKKLLNN 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515742593 315 THYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:TIGR01328 326 LKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDADDLIADLKQALDAL 391
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
1-380 |
7.29e-122 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 357.61 E-value: 7.29e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKK---TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDI--GDLR-----QGYEYSRTANPTRASIESVIANLENGKHGF 70
Cdd:PRK06767 1 MKKKhmeTALIHHGYTSEEHKGSLTPPLFQTSTFTFETAqqGEASfagvdPSYIYSRLGNPTVKLFEERMAVLEGGEEAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 71 AFGSGMAAISAVIMLLDK-GDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLL 149
Cdd:PRK06767 81 AFGSGMAAISATLIGFLKaGDHIICSNGLYGCTYGFLEVLEEKFMITHSFCDMETEADIENKIRPNTKLIFVETPINPTM 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 150 RVTDIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGG 229
Cdd:PRK06767 161 KLIDLKQVIRVAKRNGLLVIVDNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTICKTRALAEKIRPMRKDIGG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 230 VLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPsieshlNHDIHIAQASGHTGVVAFEVKDTEA-A 308
Cdd:PRK06767 241 IMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWYP------EGELASRQMKRGGGVISFSIKGGKEeT 314
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515742593 309 KQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:PRK06767 315 QAFINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWEDIVSDLEQALKKI 386
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
5-378 |
4.12e-115 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 341.01 E-value: 4.12e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDI-------GDLRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK07503 12 TRAIHHGYDPLDHGGALVPPVYLTATFAFPTAeygaecfAGEEEGHFYSRISNPTLALLEQRMASLEGGEAAVALASGMG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVI-MLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:PRK07503 92 AITATLwTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTVRHVDLTDPAALKAAISDKTRMVYFETPANPNMRLVDIAA 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGE-RLAFISNSTGGVLGPQD 235
Cdd:PRK07503 172 VAEIAHGAGAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKALADRiRLEGLKDMTGAVMSPFD 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 236 SYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK-DTEAAKQLIRE 314
Cdd:PRK07503 252 AFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGLPSFAQHALAQRQMALPGGMIAFELKgGIAAGRRFMNA 331
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515742593 315 THYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAID 378
Cdd:PRK07503 332 LQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADILADLAQALD 395
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
1-381 |
2.02e-111 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 330.64 E-value: 2.02e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGhtTDDFTGAVTTPIYQTSTYLQDdIGdlrQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAIS 80
Cdd:PRK06460 1 MKDATRTVRED--IDEATGAITTPIYQTTAYHYP-EG---EKYRYSREANPTVLELTKKIVELENAEMGVAFSSGMGAIS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 81 AVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDfVDTTNIENVKDYIKPE-TKMLYIETPSNPLLRVTDIRRAA 158
Cdd:PRK06460 75 TTALaLLKPGNSVLVHRDMFGRSYRFFTDYLKNWGVNVD-ASNPGSDNIIEKAKSKrYDVVFVENITNPLLRVVDITELS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 159 EIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNdELGERLAFISNSTGGVLGPQDSYL 238
Cdd:PRK06460 154 KVCKENGSILIVDATFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYG-KLLNVIDQMRRTLGTSLDPHAAYL 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 239 LIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK-DTEAAKQLIRETHY 317
Cdd:PRK06460 233 TLRGIKTLKIRMDVINRNAEQIAEFLEGHPKVVKVYYPGLKSHVDYEIARRVLKGFGGVLSFEVNgGQESALKVMKSLKL 312
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515742593 318 FTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTLN 381
Cdd:PRK06460 313 IIPAQTLGGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVNDLIEDLDRALSTLY 376
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
5-378 |
2.92e-110 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 327.16 E-value: 2.92e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDlRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIM 84
Cdd:PRK07269 9 TILAQAGIKSDEATGALVTPLHFSTTYQHPEFGQ-STGFDYTRTKNPTRAKLEETLAAIESADYALATSSGMSAIVLAFS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 85 LLDKGDHLILNSDVYGGTYRALTKVFT--RFGidvdFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAK 162
Cdd:PRK07269 88 VFPVGSKVVAVRDLYGGSFRWFNQQEKegRFH----FTYANTEEELIAAIEEDTDIVYIETPTNPLMVEFDIEKVAKLAH 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 163 ENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRG 242
Cdd:PRK07269 164 AKGAKVIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLAGVVVTNDLELYEKLFYNLNTTGAVLSPFDSYLLMRG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 243 IKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPsieshlnhdihiaqasGHTGVVAFEVKDTEAAKQLIRETHYFTLAE 322
Cdd:PRK07269 244 LKTLSLRMERSTANAQEVVAFLKKSPAVKEVLYT----------------GKGGMISFKVADETRIPHILNSLKVFTFAE 307
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 515742593 323 SLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAID 378
Cdd:PRK07269 308 SLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLKQALE 363
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
5-377 |
3.99e-110 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 328.10 E-value: 3.99e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQgYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVI- 83
Cdd:PRK08776 15 TAAVRAGIDRDTAYGAVTPPIVLSSNFSFDGFGNKRQ-YDYTRSGNPTRDLLGEALAELEGGAGGVITATGMGAINLVLn 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 84 MLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKE 163
Cdd:PRK08776 94 ALLQPGDTLVVPHDAYGGSWRLFNALAKKGHFALITADLTDPRSLADALAQSPKLVLIETPSNPLLRITDLRFVIEAAHK 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 164 NQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGI 243
Cdd:PRK08776 174 VGALTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGAVVARDAELHQQLVWWANALGLTGSPFDAFLTLRGL 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 244 KTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAA-KQLIRETHYFTLAE 322
Cdd:PRK08776 254 RTLDARLRVHQENADAIAALLDGHAAVNQVYYPGLASHPGHALAARQQKGFGAMLSFELEGGEAAvRAFVDGLRYFTLAE 333
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 515742593 323 SLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:PRK08776 334 SLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIESAEDLLIDLRAGL 388
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
2-380 |
7.69e-110 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 327.08 E-value: 7.69e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 2 KKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIG-------DLRQGYEYSRTANPTRASIESVIANLENGKHGFAFGS 74
Cdd:PRK08249 8 GVGTKAVWAGEKEYLPYGATQVPVVLSVAYGYDDIDewydvalGKKPGHIYSRNTNPTVQAFEEKVRILEGAEAATAFST 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 75 GMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTD 153
Cdd:PRK08249 88 GMAAISNTLYtFLKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVTLCETGDHEQIEAEIAKGCDLLYLETPTNPTLKIVD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 154 IRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGlVATSNDELGERLAFISNSTGGVLGP 233
Cdd:PRK08249 168 IERLAAAAKKVGALVVVDNTFATPINQNPLALGADLVIHSATKFLSGHADALGG-VVCGSKELMEQVYHYREINGATMDP 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 234 QDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK-DTEAAKQLI 312
Cdd:PRK08249 247 MSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYPGLETHPNHEIAKAQMRGFGGILSFVLKgGMDTVKRLL 326
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515742593 313 RETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:PRK08249 327 PKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRISVGIEDTEDLIADLEQAFAHL 394
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
2-382 |
2.20e-109 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 325.70 E-value: 2.20e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 2 KKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRqGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISA 81
Cdd:PRK08045 4 KQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPR-AHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 82 VIML-LDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEI 160
Cdd:PRK08045 83 VTTVfLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 161 AKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLI 240
Cdd:PRK08045 163 AREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLL 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 241 RGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK-DTEAAKQLIRETHYFT 319
Cdd:PRK08045 243 RGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDgDEQTLRRFLGGLSLFT 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 515742593 320 LAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTLNK 382
Cdd:PRK08045 323 LAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANK 385
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
2-377 |
1.50e-106 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 319.69 E-value: 1.50e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 2 KKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDD------IGDLRQ-GYEYSRTANPTRASIESVIANLENGKHGFAFGS 74
Cdd:TIGR01326 1 HFETLQLHAGQEPDPTTGSRAVPIYQTTSYVFDStehaaaLFGLQEpGNIYSRLMNPTTDVLEQRIAALEGGVAALAVAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 75 GMAAIS-AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTD 153
Cdd:TIGR01326 81 GQAAITyAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIEVRFVDPDDPESLEKAIDENTKAVFAETIGNPQINVLD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 154 IRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATS--------------------- 212
Cdd:TIGR01326 161 IEAIAEVAHRHGIPLIVDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVDGgkfdwnngrfplfttpdpsyh 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 213 ----NDELGErLAFISNS-------TGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESH 281
Cdd:TIGR01326 241 glvfTETLGN-PAFILKArvqllrdLGAALSPFNAFLLLQGLETLSLRMERHVENALKVAEFLESHPDVAWVNYPGLASH 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 282 LNHDihIAQ---ASGHTGVVAFEVKD-TEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLV 357
Cdd:TIGR01326 320 PHHA--LAKkylPKGFGAVLSFEIKGgREAGKKFIDALKLASHLANVGDAKSLVIHPASTTHSQLSEEEQLKAGVTPGLI 397
|
410 420
....*....|....*....|
gi 515742593 358 RLSIGIEDTEDLVQDLKQAI 377
Cdd:TIGR01326 398 RLSVGIENIDDIIADLEQAL 417
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
5-373 |
6.33e-106 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 316.94 E-value: 6.33e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFtGAVTTPIYQTSTYLQDDIGDL-------RQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK08133 9 TLAVRAGQLRSPF-GEHSEALFLTSSFVFESAAEAaarfageEPGNIYSRFTNPTVTMFQERLAALEGAEACVATASGMA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:PRK08133 88 AILAVVMaLLQAGDHVVSSRSLFGSTVSLFEKIFARFGIETTFVDLTDLDAWRAAVRPNTKLFFLETPSNPLTELADIAA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFIsNSTGGVLGPQDS 236
Cdd:PRK08133 168 LAEIAHAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVFGFL-RTAGPTLSPFNA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 237 YLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK-DTEAAKQLIRET 315
Cdd:PRK08133 247 WVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYPGLPSHPQHELAKRQQKGGGAIVSFEVKgGREAAWRVIDAT 326
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 515742593 316 HYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDL 373
Cdd:PRK08133 327 RLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADL 384
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
2-376 |
1.99e-102 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 307.98 E-value: 1.99e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 2 KKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQgYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISA 81
Cdd:PRK08861 5 KPATIAVRTGIESDSQYHAVVPPIYLSTNYGFPAFGEVPK-YDYTRSGNPNRGLLEQTLSELESGKGAVVTNCGTSALNL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 82 VIMLLDKGDHLILNS-DVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEI 160
Cdd:PRK08861 84 WVSALLGPDDLIVAPhDCYGGTYRLFNTRANKGDFKVQFVDQSDAAALDAALAKKPKLILLETPSNPLVRVVDIAELCQK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 161 AKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLI 240
Cdd:PRK08861 164 AKAVGALVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITKTKEHAEELAWWGNCIGATGTPFDSYMTL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 241 RGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDT-EAAKQLIRETHYFT 319
Cdd:PRK08861 244 RGIRTLGARMRVHEESAQQILAYLQTQSLVGTIYHPSLPEHPGHEIAKKQQSGFGSMLSFEFAGSfEQLKVFVKALALFS 323
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 515742593 320 LAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQA 376
Cdd:PRK08861 324 LAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDLIADLDQA 380
|
|
| O_suc_HS_sulf |
TIGR01325 |
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, ... |
5-377 |
2.19e-102 |
|
O-succinylhomoserine sulfhydrylase; This model describes O-succinylhomoserine sulfhydrylase, one of several related pyridoxal phosphate-dependent enzymes of cysteine and methionine metabolism. This enzyme is part of an alternative pathway of homocysteine biosynthesis, a step in methionine biosynthesis. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 188131 Cd Length: 381 Bit Score: 307.54 E-value: 2.19e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFtGAVTTPIYQTSTYLQDDIGDLRQ-------GYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:TIGR01325 2 TLAVRGGMLRSGF-EETAEALYLTSGYVYDSAAVAAKrfagelpGFVYSRYGNPTVSVFEERLALLEGAEAAVATASGMA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:TIGR01325 81 AIFAALMaLLGAGDHVVASRSLFGSCFVVCSEILPRFGVQTVFVDGTDLSAWEAALKPNTKAVFVETPSNPLQELVDIAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDS 236
Cdd:TIGR01325 161 VAELAHAAGAKVVVDNVFATPLLQQPLKLGADVVVYSATKHIDGQGRVLGGAILGSEEYMDEPVQKLLRHTGPAMSPFNA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 237 YLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQLIRETH 316
Cdd:TIGR01325 241 WVLLKGLETLAIRVQHQNASALAIAEWLNGHPSVQWVYYPGLPSHPQHELAKRQMSGGGTVVTFDLDCRQAAFKVLDAMR 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515742593 317 YFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:TIGR01325 321 LVDISNNLGDAKSTITHPATTTHRRMGPEERAAAGIGDGLVRLSVGLEDVDDLIADIDRAL 381
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
1-377 |
2.25e-102 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 307.76 E-value: 2.25e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGgHTTDDFTGAVTTPIYQTSTYLQDD---IGDLRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK08574 1 MRRGTDAVRG-YRGSDPYGSLQPPIYLTALFRQEGeayPSDRGFDLKYSREENPTLRPLEEALAKLEGGVDALAFNSGMA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVIM-LLDKGDHLILNSDVYGGTYRaLTKVFTRFGIDVDFV--DT-TNIENVKDyikPETKMLYIETPSNPLLRVTD 153
Cdd:PRK08574 80 AISTLFFsLLKAGDRVVLPMEAYGTTLR-LLKSLEKFGVKVVLAypSTeDIIEAIKE---GRTKLVFIETMTNPTLKVID 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 154 IRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGP 233
Cdd:PRK08574 156 VPEVAKAAKELGAILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAVAWSGEFLEELWEWRRRLGTIMQP 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 234 QDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIhiaqASG------HTGVVAFEVK-DTE 306
Cdd:PRK08574 236 FEAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYPGLPSDPYHGV----AKRlfgkdlYGGVVSFRVKgGRD 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515742593 307 AAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:PRK08574 312 AVLKFLRSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDLDQAL 382
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
5-378 |
1.38e-100 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 302.98 E-value: 1.38e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYL-----QDDIGDLRQG--YEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK06434 11 TRAVQSGELRDPRFGNVTTPIFETSTFVypnseKEAYMDSTRGmpYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSGMG 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVkDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:PRK06434 91 AITSAILsLIKKGKRILSISDLYGQTFYFFNKVLKTLGIHVDYIDTDRLNSL-DFDPSNYDLIYAESITNPTLKVPDIKN 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLIsvVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDS 236
Cdd:PRK06434 170 VSSFCHENDVI--VDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGVAGTNNKSIFNNLVERRKTLGSNPDPIQA 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 237 YLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIEshlnhdIHIAQASGHTGVVAFEVKDTEAAKQLIRETH 316
Cdd:PRK06434 248 YLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYYPDTE------IGKKVLRGFGGMLSFELRSMEDVHKFIRNLE 321
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515742593 317 YFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAID 378
Cdd:PRK06434 322 IPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALS 383
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
11-377 |
4.84e-92 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 281.58 E-value: 4.84e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 11 GHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQGYE-------YSRTANPTRASIESVIANLENGKHGFAFGSGMAAISA-V 82
Cdd:PRK05968 16 AHDEGNAFDAVVPPIFQTSLFTFDSYDEMEDVYAgekvrpiYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISStV 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 83 IMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIkPETKMLYIETPSNPLLRVTDIRRAAEIAK 162
Cdd:PRK05968 96 LSFVEPGDRIVAVRHVYPDAFRLFETILKRMGVEVDYVDGRDEEAVAKAL-PGAKLLYLESPTSWVFELQDVAALAALAK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 163 ENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRG 242
Cdd:PRK05968 175 RHGVVTMIDNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIARINAEAYPYLGAKLSPFEAWLLLRG 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 243 IKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNhdihiAQASGHTGVVAFEVKDTEAAKQLIRETHYFTLAE 322
Cdd:PRK05968 255 LRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPP-----AGLSGTSGLFSFIFREGIDVRAFADALKLFRLGV 329
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 515742593 323 SLGAVESLIsVPALMTHA-SIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:PRK05968 330 SWGGHESLV-VPAEVVLQqKAQPNSAARFGVSPRSVRLHVGLEGTEALWADLEQAL 384
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
43-380 |
3.38e-90 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 275.72 E-value: 3.38e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 43 YEYSRTANPTRASIESVIANLEnGKHGFAFGSGMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVD 121
Cdd:PRK07582 43 DTYGRASNPTWRALEAALGELE-GAEALVFPSGMAAITAVLRaLLRPGDTVVVPADGYYQVRALAREYLAPLGVTVREAP 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 122 TTNIenVKDYIKPeTKMLYIETPSNPLLRVTDIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGH 201
Cdd:PRK07582 122 TAGM--AEAALAG-ADLVLAETPSNPGLDVCDLAALAAAAHAAGALLVVDNTTATPLGQRPLELGADLVVASDTKALTGH 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 202 SDVVAGLVATSNDELGERLAFISNSTGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESH 281
Cdd:PRK07582 199 SDLLLGYVAGRDPELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFARQCANALAVAELLAGHPAVRGVRYPGLPGD 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 282 LNHDIHIAQASGHTGVVAFEVKDTEAAKQLIRETHYFTLAESLGAVeslisvpalmtHASipADVRAKEG--ITDGLVRL 359
Cdd:PRK07582 279 PAHEVAARQMRRFGGLVSFELADAAAAERFVAASRLVVAATSFGGV-----------HTS--ADRRARWGdaVPEGFVRL 345
|
330 340
....*....|....*....|.
gi 515742593 360 SIGIEDTEDLVQDLKQAIDTL 380
Cdd:PRK07582 346 SCGIEDTDDLVADLERALDAL 366
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
5-382 |
6.89e-89 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 274.69 E-value: 6.89e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDL-------RQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK08134 11 TLALHAGAAPDPATGARAVPIHLTTSFVFRDSDHAaalfnleRAGHVYSRISNPTVAVLEERVAALEGGVGAIATASGQA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AIS-AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:PRK08134 91 ALHlAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTFVKPGDIDGWRAAIRPNTRLLFGETLGNPGLEVLDIPT 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSND----------ELGERLA----- 221
Cdd:PRK08134 171 VAAIAHEAGVPLLVDSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGVLVDGGRfdweasgkfpELTEPYAgfhgm 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 222 -FISNST----------------GGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNH 284
Cdd:PRK08134 251 vFAEESTvaafllrarreglrdfGACLSPMNAWQLLQGIETLPLRMERHVANTRKVVAFLASHPAVARVAHPELESHPDH 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 285 DihIAQ---ASGHTGVVAFEVK-DTEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLS 360
Cdd:PRK08134 331 A--LAKrllPRGAGSVFSFDLKgGRAAGRKFIESLKLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIGEGTIRLS 408
|
410 420
....*....|....*....|..
gi 515742593 361 IGIEDTEDLVQDLKQAIDTLNK 382
Cdd:PRK08134 409 IGLEDADDLIDDLKRALKAAEK 430
|
|
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
1-378 |
9.13e-87 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 269.23 E-value: 9.13e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQGYE-----------------YSRTANPTRASIESVIANL 63
Cdd:PRK07049 16 LHPETQMLNYGYDPELSEGAVKPPVFLTSTFVFRSAEDGRDFFDyvsgrkeppagegaglvYSRFNHPNSEIVEDRLAVY 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 64 ENGKHGFAFGSGMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGID-VDFVDTTNIENVKDYI-----KPET 136
Cdd:PRK07049 96 EGAESAALFSSGMSAIATTLLaFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGaVGFADGLSEAAIGAAAeaaaaKGRV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 137 KMLYIETPSNP---LLRVTDIRRAAEIAKENQL---ISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVa 210
Cdd:PRK07049 176 SLILIETPANPtnsLVDVAAVRRVADAIEARQGhrpIIACDNTLLGPVFQKPLEHGADLSVYSLTKYVGGHSDLVAGAV- 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 211 TSNDELGERLAFISNSTGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQV-FHPSIESHLNH-DIHI 288
Cdd:PRK07049 255 LGRKALIRQVRALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLhYLPFLDPDSAYgAVYK 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 289 AQASGHTGVVAFEVKDTEAAK-QLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTE 367
Cdd:PRK07049 335 RQCTGAGSTFSFDIKGGQAAAfRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVLESTIRLSIGIEHPD 414
|
410
....*....|.
gi 515742593 368 DLVQDLKQAID 378
Cdd:PRK07049 415 DLIADLAQALD 425
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
5-375 |
3.51e-82 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 257.76 E-value: 3.51e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDD-------IGDLRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK07812 16 TKQIHAGQTPDPATNARALPIYQTTSYTFDDtdhaaalFGLAEPGNIYTRIMNPTQDVVEQRIAALEGGVAALLLASGQA 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AIS-AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFV-DTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIR 155
Cdd:PRK07812 96 AETfAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIEVSFVeDPDDLDAWRAAVRPNTKAFFAETISNPQIDVLDIP 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 156 RAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVA---------------TSND------ 214
Cdd:PRK07812 176 GVAEVAHEAGVPLIVDNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdggtfdwtqgrfpgfTTPDpsyhgv 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 215 ---ELGErLAFISNS-------TGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNH 284
Cdd:PRK07812 256 vfaELGP-PAYALKArvqllrdLGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAEFLEARDEVASVNYAGLPSSPWY 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 285 DIHIAQASGHTG-VVAFEVKD-TEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIG 362
Cdd:PRK07812 335 ERAKRLAPKGTGaVLSFELAGgVEAGKAFVNALTLHSHVANIGDVRSLVIHPASTTHSQLTPEEQLATGVTPGLVRLAVG 414
|
410
....*....|...
gi 515742593 363 IEDTEDLVQDLKQ 375
Cdd:PRK07812 415 IEGIDDILADLEA 427
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
2-379 |
3.27e-81 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 253.91 E-value: 3.27e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 2 KKKTQMIHGGHTTDDFtGAVTTPIYQTSTYLQDDI--------GDlRQGYEYSRTANPTRASIESVIANLENGKHGFAFG 73
Cdd:PRK07504 10 RPATRLVHSGTLRSQF-GETSEALFLTQGFVYDTAeaaearfkGE-DPGFIYSRYSNPTVDMFEKRMCALEGAEDARATA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 74 SGMAAISAVIML-LDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVT 152
Cdd:PRK07504 88 SGMAAVTAAILCqVKAGDHVVAARALFGSCRYVVETLLPRYGIESTLVDGLDLDNWEKAVRPNTKVFFLESPTNPTLEVI 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 153 DIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLG 232
Cdd:PRK07504 168 DIAAVAKIANQAGAKLVVDNVFATPLFQKPLELGAHIVVYSATKHIDGQGRCLGGVVLSDKAWIEEHLQDYFRHTGPSLS 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 233 PQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK-DTEAAKQL 311
Cdd:PRK07504 248 PFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARVIYPGRADHPQADIIAKQMTGGSTLVAFELKgGKEAAFRF 327
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515742593 312 IRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDT 379
Cdd:PRK07504 328 LNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAELGISEGFLRLSAGLEDTDDLIEDLAAALKK 395
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
19-380 |
7.79e-81 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 253.07 E-value: 7.79e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 19 GAVTTPIYQTSTYLQDDIGDL-------RQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIM-LLDKGD 90
Cdd:PRK05939 8 GAVHKPIHTSVTYGYEDARDLidvfqgkKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAAVFLtLLRAGD 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 91 HLILNSDVYGGTyRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEIAKENQLISVV 170
Cdd:PRK05939 88 HLVSSQFLFGNT-NSLFGTLRGLGVEVTMVDATDVQNVAAAIRPNTRMVFVETIANPGTQVADLAGIGALCRERGLLYVV 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 171 DNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVA-----------------TSNDELGERLAFISN----STGG 229
Cdd:PRK05939 167 DNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAVTdtglfdwsaypnifpayRKGDPQQWGLTQIRKkglrDMGA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 230 VLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAK 309
Cdd:PRK05939 247 TLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYPGLASHPQHARATELFRHYGGLLSFELADGIDCF 326
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515742593 310 QLIRETHYFTLAESLGAVESLIsVPALMT-HASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:PRK05939 327 DFLNRLKLVIKATHLGDTRTLV-IPVAPTiYYEMGAERRASMGIADSLIRVSVGIEDEADLIADFEQALDAT 397
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
4-377 |
1.14e-80 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 253.61 E-value: 1.14e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 4 KTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDD-------IGDLRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGM 76
Cdd:PRK08248 10 ETLAIHAGQEIDPTTGSRAVPIYQTTSYGFRDsehaanlFSLKEFGNIYTRIMNPTTDVFEKRIAALEGGIGALAVSSGQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 77 AAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIR 155
Cdd:PRK08248 90 AAITYSILnIASAGDEIVSSSSLYGGTYNLFAHTLPKLGITVKFVDPSDPENFEAAITDKTKALFAETIGNPKGDVLDIE 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 156 RAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSN---------------------- 213
Cdd:PRK08248 170 AVAAIAHEHGIPLIVDNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVDSGkfdwkgsgkfpgltepdpsyhg 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 214 ----DELGErLAFISNS-------TGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHL 282
Cdd:PRK08248 250 lvytDAVGE-AAYITKArvqllrdLGAALSPFNSFLLLQGLETLHLRMERHSENALAVAKFLEEHEAVEWVSYPGLPSHP 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 283 NHDihIAQA---SGHTGVVAFEVK-DTEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVR 358
Cdd:PRK08248 329 SYE--LAKKylpKGQGAILTFGIKgGVEAGKKLIDSVKLFSHLANVGDSKSLIIHPASTTHQQLSEEEQLAAGVTPGLVR 406
|
410
....*....|....*....
gi 515742593 359 LSIGIEDTEDLVQDLKQAI 377
Cdd:PRK08248 407 LSVGTEAIDDILDDLRQAI 425
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
5-377 |
5.35e-75 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 238.09 E-value: 5.35e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFtGAVTTPIYQTSTYLQDDIGDLRQG-------YEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK07810 18 TIGVRGGLLRSGF-EETAEALYLTSGYVYESAAAAEAAftgeldrFVYSRYGNPTVSMFEERLRLIEGAEACFATASGMS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AI-SAVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:PRK07810 97 AVfTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETVFVDGEDLSQWEEALSVPTQAVFFETPSNPMQSLVDIAA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQDS 236
Cdd:PRK07810 177 VSELAHAAGAKVVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRHTGPALSAFNA 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 237 YLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTE-AAKQ----L 311
Cdd:PRK07810 257 WVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRYPFLPSHPQYDLAKRQMSGGGTVVTFELDAPEdAAKKrafeV 336
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515742593 312 IRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAI 377
Cdd:PRK07810 337 LDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGLGDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
5-377 |
1.14e-74 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 238.07 E-value: 1.14e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGD------LRQ-GYEYSRTANPTRASIESVIANLENGKHGFAFGSGMA 77
Cdd:PRK05994 10 TLAVHAGAQPDPTTGARATPIYQTTSFVFNDADHaaslfgLQAfGNIYTRITNPTNAVLEERVAALEGGTAALAVASGHA 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 78 AISAVI-MLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRR 156
Cdd:PRK05994 90 AQFLVFhTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVRWADADDPASFERAITPRTKAIFIESIANPGGTVTDIAA 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 157 AAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLV---ATSNDELGERLAFISN---STGG- 229
Cdd:PRK05994 170 IAEVAHRAGLPLIVDNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGIIvdgGTFDWSKSGKYPMLSEprpEYHGl 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 230 ----------------VLG---------PQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNH 284
Cdd:PRK05994 250 vlhetfgnfafaiaarVLGlrdlgpaisPFNAFLILTGIETLPLRMQRHSDNALAVAEWLKGHPKVSWVNYAGLPDDPYH 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 285 DIHIAQASGHTGVV-AFEVKDT-EAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVRLSIG 362
Cdd:PRK05994 330 ALAQKYSPKGAGAVfTFGLKGGyEAGVKLVSSLKLFSHLANIGDTRSLVIHPASTTHRQLTDEQKVAAGAGPDVVRLSIG 409
|
410
....*....|....*
gi 515742593 363 IEDTEDLVQDLKQAI 377
Cdd:PRK05994 410 IEDVDDIIADLEQAL 424
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
1-378 |
7.93e-74 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 235.57 E-value: 7.93e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDD------IGDLR-QGYEYSRTANPTRASIESVIANLENGKHGFAFG 73
Cdd:PRK06084 1 MKLETLAIHAGYSPDPTTKAVAVPIYQTTSYAFDDtqhgadLFDLKvPGNIYTRIMNPTNDVLEQRVAALEGGVGALAVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 74 SGMAAIS-AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVT 152
Cdd:PRK06084 81 SGMAAITyAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIETRFAAHDDIAALEALIDERTKAVFCESIGNPAGNII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 153 DIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSND----ELGERLAFISN--- 225
Cdd:PRK06084 161 DIQALADAAHRHGVPLIVDNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGGIVVDSGKfpwaEHKERFALLNTpdp 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 226 --------------------------STGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIE 279
Cdd:PRK06084 241 syhgvtyteafgpaafigrcrvvplrNMGAALSPFNAFLILQGLETLALRMERHTENALKVARYLQQHPQVAWVKYAGLP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 280 SHLNHDIHIAQASGH-TGVVAFEVK-DTEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLV 357
Cdd:PRK06084 321 DHPEHELARRYMGGKpASILSFGIKgGQAAGARFIDALKLVVRLVNIGDAKSLACHPASTTHRQLNDEELEKAGVSRDMV 400
|
410 420
....*....|....*....|.
gi 515742593 358 RLSIGIEDTEDLVQDLKQAID 378
Cdd:PRK06084 401 RLSIGIEHIDDIIADLAQALD 421
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
5-380 |
4.21e-68 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 219.36 E-value: 4.21e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLR---QGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAIS- 80
Cdd:TIGR01324 1 TRLIHSGRQPRFSQGSVNPPLQRASTVLFDSHAAQRrakGELTYGRRGTLTHFALQDAMCELEGGAGCYLYPSGLAAVTn 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 81 AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEI 160
Cdd:TIGR01324 81 SILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGEDIATLIQPNTKVLFLEAPSSITFEIQDIPAIAKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 161 AKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATsNDELGERLAFISNSTGGVLGPQDSYLLI 240
Cdd:TIGR01324 161 ARNPGIVIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVA-NARTWDQLREHSYLMGQMVDADDAYTTL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 241 RGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK--DTEAAKQLIRETHYF 318
Cdd:TIGR01324 240 RGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHPALPSCPGHEFWKRDFSGSSGLFSFVLQrlTQKQVHAFLDHLQLF 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515742593 319 TLAESLGAVESLisvpALMTHASIPADVRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:TIGR01324 320 GLGYSWGGYESL----ALCNQPELGHRPNIKRNLEGPLIRVHIGLENVDDLKADLKAGFEAI 377
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
1-382 |
9.14e-68 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 219.22 E-value: 9.14e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKKTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQGYE--------YSRTANPTRASIESVIANLENGKHGFAF 72
Cdd:PRK09028 3 EKKATKIVSAGRDKKWTKGVINPPVFRASTVVFDTVAEMRHAAKnrangemfYGRRGTPTHFAFQAAIVELEGGAGTALY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 73 GSGMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRV 151
Cdd:PRK09028 83 PSGAAAISNALLsFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYDPMIGEGIRELIRPNTKVLFLESPGSITMEV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 152 TDIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGlVATSNDELGERLAFISNSTGGVL 231
Cdd:PRK09028 163 QDVPTLSRIAHEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLG-TATANEKHWDQLREHSYLMGQCT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 232 GPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVK--DTEAAK 309
Cdd:PRK09028 242 SPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAFETCPGHEFFKRDFSGSNGLFSFVLKqgDPKAVT 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515742593 310 QLIRETHYFTLAESLGAVESLI----SVPALMThasipadvRAKEGITDGLVRLSIGIEDTEDLVQDLKQAIDTLNK 382
Cdd:PRK09028 322 ALVEGMQHFKMGFSWGGFESLIlgvfGINKLRT--------ATNWDFSKPLIRLHIGLEDVDDLIADLEAGFERYNA 390
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
4-380 |
2.58e-65 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 213.96 E-value: 2.58e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 4 KTQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQ-------GYEYSRTANPTRASIESVIANLENGKHGFAFGSGM 76
Cdd:PRK05613 15 ETRSIHAGQSVDSDTSARNLPIYQTTSYVFDSAEHAKQrfaledlGPIYSRLTNPTVEALENRIASLEGGVHAVAFASGQ 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 77 AAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFV-DTTNIENVKDYIKPETKMLYIETPSNPLLRVTDI 154
Cdd:PRK05613 95 AAETAAILnLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIEVTFVeNPDDPESWQAAVQPNTKAFFGETFANPQADVLDI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 155 RRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSND-------------------- 214
Cdd:PRK05613 175 PAVAEVAHRNQVPLIVDNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLIDGGKfdwtverdgkpvfpyfvtpd 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 215 ---------ELGErLAF-------ISNSTGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSI 278
Cdd:PRK05613 255 payhglkyaDLGA-PAFglkaragLLRDTGATLSPFNAWVTAQGLDTLSLRLERHNENAIKVAEFLNNHEKVAKVNFAGL 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 279 ESHLNHDIHIAQASGHTG-VVAFEVKD-TEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGL 356
Cdd:PRK05613 334 KDSPWYATKEKLGLKYTGsVLSFDIKGgKDEAWAFIDALKLHSNLANIGDVRSLVVHPATTTHSQSDEAGLARAGITQAT 413
|
410 420
....*....|....*....|....
gi 515742593 357 VRLSIGIEDTEDLVQDLKQAIDTL 380
Cdd:PRK05613 414 VRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
5-373 |
1.18e-64 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 211.21 E-value: 1.18e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 5 TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLR---QGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISA 81
Cdd:PRK05967 15 TRLAHDGNDPGDYHGFVNPPVVHASTVLFPDAETMAtrgQKYTYGTRGTPTTDALCKAIDALEGSAGTILVPSGLAAVTV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 82 VIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDIRRAAEI 160
Cdd:PRK05967 95 PFLgFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVEVEYYDPEIGAGIAKLMRPNTKVVHTEAPGSNTFEMQDIPAIAEA 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 161 AKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATsNDELGERLAFISNSTGGVLGPQDSYLLI 240
Cdd:PRK05967 175 AHRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSA-NEKCWPQLLEAHGTLGLCAGPDDTYQIL 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 241 RGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQliRETH---- 316
Cdd:PRK05967 254 RGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHPALPSFPGHEIWKRDFSGASGIFSFVLAAGPEKGK--AKAHafld 331
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515742593 317 ---YFTLAESLGAVESLisvpALmtHASIpADVRAKEGITDG-LVRLSIGIEDTEDLVQDL 373
Cdd:PRK05967 332 aleIFGLGYSWGGYESL----AL--HVKL-GDRTVAKAPYAGpVIRLQIGLEDVPDLKADL 385
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
4-382 |
1.50e-61 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 203.03 E-value: 1.50e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 4 KTQMIHG-GHTTDDFTgAVTTPIYQTSTYLQDDIGDLRQ-------GYEYSRTANPTRASIESVIANLENGKHGFAFGSG 75
Cdd:PRK07050 11 QTRIVQPdDQIPPGFR-SFVTPVARASTVVFPDLATMRAldwrqdvQWRYGLHATPTSLALAQRLAEIEGGRHALLQPSG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 76 MAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPLLRVTDI 154
Cdd:PRK07050 90 LAAISLVYFgLVKAGDDVLIPDNAYGPNRDHGEWLARDFGITVRFYDPLIGAGIADLIQPNTRLIWLEAPGSVTMEVPDV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 155 RRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSNDELGERLAFISNSTGGVLGPQ 234
Cdd:PRK07050 170 PAITAAARARGVVTAIDNTYSAGLAFKPFEHGVDISVQALTKYQSGGSDVLMGATITADAELHAKLKLARMRLGIGVSAD 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 235 DSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKDTEAAKQ---L 311
Cdd:PRK07050 250 DCSLVLRGLPSLQVRLAAHDRSALEVAEWLKARPEIATVLHPALPDCPGHAFWMRDFTGAGGLFSVVFDERYSPAQvdaF 329
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515742593 312 IRETHYFTLAESLGAVESLiSVP---ALMTHASIPADVRakegitdgLVRLSIGIEDTEDLVQDLKQAIDTLNK 382
Cdd:PRK07050 330 VEALELFAIGWSWGGACSL-AMPydvASMRTAKWPHRGT--------LVRLYIGLEDEADLIADLEQALEAALA 394
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
35-380 |
1.32e-57 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 193.44 E-value: 1.32e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 35 DIGDLRQGYEYSRTANPTRASIESVIANLENGKHGFAFGSGMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTKVFTR- 112
Cdd:PLN02242 60 ELGPDRDFYIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGMSAISSVLLqLCSSGGHVVASNTLYGGTHALLAHFLPRk 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 113 FGIDVDFVDTTNIENVKDYIKP-ETKMLYIETPSNPLLRVTDIRRAAEIAKENQLISVVDNTFmTPYYQNPLDFGIDIVL 191
Cdd:PLN02242 140 CNITTTFVDITDLEAVKKAVVPgKTKVLYFESISNPTLTVADIPELARIAHEKGVTVVVDNTF-APMVLSPARLGADVVV 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 192 HSATKYIGGHSDVVAGLVATSNDELGERLAFISNST---GGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHP 268
Cdd:PLN02242 219 HSISKFISGGADIIAGAVCGPAELVNSMMDLHHGALmllGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEYAKRMKELG 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 269 SvqQVFHPSIESHLNHDIHIAQAS---GHTGVVAFEVKDTEAAKQLIRE----THYFTLAESLGAVESLISVPALMTHAS 341
Cdd:PLN02242 299 L--KVIYPGLEDHPQHALLKSMANkgyGFGGLLCLDMDTEERANRLMRYlqnsTQFGFMAVSLGYYETLMSCSGSSTSSE 376
|
330 340 350
....*....|....*....|....*....|....*....
gi 515742593 342 IPADVRAKEGITDGLVRLSIGIEDTedLVQDLKQAIDTL 380
Cdd:PLN02242 377 LDPEEKAAAGISPGLVRMSVGYTGT--LEQRWSQFEKAL 413
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
3-377 |
5.56e-56 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 189.49 E-value: 5.56e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 3 KKTQMIHGGHTTDDFTGAVTtPIYQTSTYLQDDIGDLR-------QGYEYSRTANPTRASIESVIANLENGKHGFAFGSG 75
Cdd:PRK06702 7 KGTICVQGGYTPKNGEPRVL-PLYQSTTYKYDTSDDLAalfnleaEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATASG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 76 MAAIS-AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTT-NIENVKDYIKPETKMLYIETPSNPLLRVTD 153
Cdd:PRK06702 86 QAAIMlAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNlTADEIVALANDKTKLVYAESLGNPAMNVLN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 154 IRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGLVATSND---------ELGER----- 219
Cdd:PRK06702 166 FKEFSDAAKELEVPFIVDNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIDGGNfdwtngkypELVEPdpsyh 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 220 -LAFISN----------------STGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHL 282
Cdd:PRK06702 246 gVSYVQNfgaaayivkarvqllrDYGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHERIEWVNYPGLDSNE 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 283 NHDihIAQ---ASGHTGVVAFEVK-DTEAAKQLIRETHYFTLAESLGAVESLISVPALMTHASIPADVRAKEGITDGLVR 358
Cdd:PRK06702 326 NYS--LAQkylKKGASGVLTFGIKgGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLSAEDQRLAGVTSDLIR 403
|
410
....*....|....*....
gi 515742593 359 LSIGIEDTEDLVQDLKQAI 377
Cdd:PRK06702 404 LSVGIEDVSDIIADLEAAL 422
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
1-374 |
1.07e-53 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 182.60 E-value: 1.07e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 1 MKKK---TQMIHGGHTTDDFTGAVTTPIYQTSTYLQDDIGDLRQGYE--------YSRTANPTRASIESVIANLENGKHG 69
Cdd:PRK08114 1 MTDKkldTQLVNAGRSKKYTQGSVNSVIQRASSLVFDSVEAKKHATRnrangelfYGRRGTLTHFSLQEAMCELEGGAGC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 70 FAFGSGMAAIS-AVIMLLDKGDHLILNSDVYGGTYRALTKVFTRFGIDVDFVDTTNIENVKDYIKPETKMLYIETPSNPL 148
Cdd:PRK08114 81 ALYPCGAAAVAnAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGADIAKLIQPNTKVVFLESPGSIT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 149 LRVTDI----RRAAEIAKEnqLISVVDNTFMTPYYQNPLDFGIDIVLHSATKYIGGHSDVVAGlVATSNDELGERLAFIS 224
Cdd:PRK08114 161 MEVHDVpaivAAVRSVNPD--AVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIG-TAVANARCWEQLRENS 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 225 NSTGGVLGPQDSYLLIRGIKTLGLRMEQINRNVEGIVKMLQEHPSVQQVFHPSIESHLNHDIHIAQASGHTGVVAFEVKD 304
Cdd:PRK08114 238 YLMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARVNHPALPGCKGHEFWKRDFTGSSGLFSFVLKK 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515742593 305 TEAAKQLIR---ETHYFTLAESLGAVESLISvpalmthASIPADVRA-----KEGITDGLVRLSIGIEDTEDLVQDLK 374
Cdd:PRK08114 318 KLTDEQLANyldNFSLFSMAYSWGGFESLIL-------ANQPEEIAAirpagEVDFTGTLIRLHIGLEDVDDLIADLA 388
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
60-268 |
3.72e-11 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 63.90 E-value: 3.72e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 60 IANLENGKHGFA-------FGSG-MAAISAVIM-LLDKGDHLILNSDVYGGtYRAltkVFTRFGIDVDFVDTT------- 123
Cdd:cd00609 45 IAEWLGRRGGVDvppeeivVTNGaQEALSLLLRaLLNPGDEVLVPDPTYPG-YEA---AARLAGAEVVPVPLDeeggfll 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 124 NIENVKDYIKPETKMLYIETPSNP---LLRVTDIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGID--------IVLH 192
Cdd:cd00609 121 DLELLEAAKTPKTKLLYLNNPNNPtgaVLSEEELEELAELAKKHGILIISDEAYAELVYDGEPPPALAlldayervIVLR 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 193 SATKYIGghsdvVAGL----VATSNDELGERLAFISNSTGGVLGPQDSYLLIRGIKT----LGLRMEQINRNVEGIVKML 264
Cdd:cd00609 201 SFSKTFG-----LPGLrigyLIAPPEELLERLKKLLPYTTSGPSTLSQAAAAAALDDgeehLEELRERYRRRRDALLEAL 275
|
....
gi 515742593 265 QEHP 268
Cdd:cd00609 276 KELG 279
|
|
| AAT_I |
cd01494 |
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP) ... |
67-200 |
1.39e-08 |
|
Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. Structure and sequence analysis has revealed that the PLP dependent enzymes can be classified into four major groups of different evolutionary origin: aspartate aminotransferase superfamily (fold type I), tryptophan synthase beta superfamily (fold type II), alanine racemase superfamily (fold type III), and D-amino acid superfamily (fold type IV) and Glycogen phophorylase family (fold type V).
Pssm-ID: 99742 [Multi-domain] Cd Length: 170 Bit Score: 53.93 E-value: 1.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 67 KHGFAFGSGMAAISAVIM-LLDKGDHLILNSDVYGGTYRALTkvfTRFGIDVDFVDTTNIENVKDYI--------KPETK 137
Cdd:cd01494 18 DKAVFVPSGTGANEAALLaLLGPGDEVIVDANGHGSRYWVAA---ELAGAKPVPVPVDDAGYGGLDVaileelkaKPNVA 94
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515742593 138 MLYIETPSNPLLRVTDIRRAAEIAKENQLISVVDNTFMTPYYQNP----LDFGIDIVLHSATKYIGG 200
Cdd:cd01494 95 LIVITPNTTSGGVLVPLKEIRKIAKEYGILLLVDAASAGGASPAPgvliPEGGADVVTFSLHKNLGG 161
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
75-172 |
1.01e-06 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 50.13 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 75 GMAAISAVIM-LLDKGDHLILNSDVYGgTYRALTKVFtrfGIDVDFVDTT-------NIENVKDYIKPETKMLYIETPSN 146
Cdd:COG0436 99 AKEALALALLaLLNPGDEVLVPDPGYP-SYRAAVRLA---GGKPVPVPLDeengflpDPEALEAAITPRTKAIVLNSPNN 174
|
90 100
....*....|....*....|....*....
gi 515742593 147 P---LLRVTDIRRAAEIAKENQLISVVDN 172
Cdd:COG0436 175 PtgaVYSREELEALAELAREHDLLVISDE 203
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
77-171 |
1.93e-05 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 46.18 E-value: 1.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 77 AAISAVIM-LLDKGDHLILNSDVY----------GGTYRALTKV--FTRFGIDVDfvdttnieNVKDYIKPETKMLYIET 143
Cdd:PRK07777 96 EAIAAAVLgLVEPGDEVLLIEPYYdsyaaviamaGAHRVPVPLVpdGRGFALDLD--------ALRAAVTPRTRALIVNS 167
|
90 100 110
....*....|....*....|....*....|.
gi 515742593 144 PSNP---LLRVTDIRRAAEIAKENQLISVVD 171
Cdd:PRK07777 168 PHNPtgtVLTAAELAAIAELAVEHDLLVITD 198
|
|
| PRK00451 |
PRK00451 |
aminomethyl-transferring glycine dehydrogenase subunit GcvPA; |
103-190 |
7.76e-04 |
|
aminomethyl-transferring glycine dehydrogenase subunit GcvPA;
Pssm-ID: 234769 [Multi-domain] Cd Length: 447 Bit Score: 41.28 E-value: 7.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 103 YRALTKVFTRF-GIDVDFVD----TTNIENVKDYIKPETKMLYIETPsNPLLRVTDIRRAAEIAKENQLISVVdntfmtp 177
Cdd:PRK00451 167 YREVLKTYLKGqGIEVVEVPyedgVTDLEALEAAVDDDTAAVVVQYP-NFFGVIEDLEEIAEIAHAGGALFIV------- 238
|
90 100
....*....|....*....|..
gi 515742593 178 yYQNPL---------DFGIDIV 190
Cdd:PRK00451 239 -GVDPVslgllkppgEYGADIV 259
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
68-163 |
8.41e-04 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 41.08 E-value: 8.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 68 HGfAFGSGMAAISAvimLLDKGDHLIlnsDVYGgTYRALTKVFTRFGIDVDFVDTT-------NIENVKDYIKPETKMLY 140
Cdd:PRK07324 87 NG-ATGANFLVLYA---LVEPGDHVI---SVYP-TYQQLYDIPESLGAEVDYWQLKeengwlpDLDELRRLVRPNTKLIC 158
|
90 100
....*....|....*....|....*.
gi 515742593 141 IETPSNP---LLRVTDIRRAAEIAKE 163
Cdd:PRK07324 159 INNANNPtgaLMDRAYLEEIVEIARS 184
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
66-171 |
1.13e-03 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 40.88 E-value: 1.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 66 GKHGF--AFgsgMAaisavimLLDKGDHLILnSDVYGGTYRALTK------VFTRFGIDVDFVDTtnIENVKDYIKPETK 137
Cdd:PRK05764 100 AKQALynAF---MA-------LLDPGDEVII-PAPYWVSYPEMVKlaggvpVFVPTGEENGFKLT--VEQLEAAITPKTK 166
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 515742593 138 MLYIETPSNPllrvT-------DIRRAAEIAKENQLISVVD 171
Cdd:PRK05764 167 ALILNSPSNP----TgavyspeELEAIADVAVEHDIWVLSD 203
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
112-283 |
1.71e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 40.12 E-value: 1.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 112 RFGIDVDFVDTTNIEN--------VKDYIKPETKMLYIETPSNPL-LRVT--DIRRAAEIAKENQLISVVDNTFMTPYYQ 180
Cdd:PRK06225 126 RFGAEVIEVPIYSEECnykltpelVKENMDENTRLIYLIDPLNPLgSSYTeeEIKEFAEIARDNDAFLLHDCTYRDFARE 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 181 NPLDFGID----IVLHSATKYIGGHSDVVAGLVATSndELGERLAFISNStggVLGPQ--DSYLLIRGIKTLGLRMEQIN 254
Cdd:PRK06225 206 HTLAAEYApehtVTSYSFSKIFGMAGLRIGAVVATP--DLIEVVKSIVIN---DLGTNviAQEAAIAGLKVKDEWIDRIR 280
|
170 180 190
....*....|....*....|....*....|
gi 515742593 255 RNVEGIVKMLQEHPS-VQQVFHPSIESHLN 283
Cdd:PRK06225 281 RTTFKNQKLIKEAVDeIEGVFLPVYPSHGN 310
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
72-213 |
4.01e-03 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 38.83 E-value: 4.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 72 FGSGM-AAISAVIMLL-DKGDhLILNSDVYggtYRALTKVFTRFGIDVDFVDTTNIEN-------VKDYIKPETKMLYIE 142
Cdd:pfam00155 68 FGSGAgANIEALIFLLaNPGD-AILVPAPT---YASYIRIARLAGGEVVRYPLYDSNDfhldfdaLEAALKEKPKVVLHT 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515742593 143 TPSNP---LLRVTDIRRAAEIAKENQLISVVDNTFMTPYYQNPLDFGI---------DIVLHSATK----------YIGG 200
Cdd:pfam00155 144 SPHNPtgtVATLEELEKLLDLAKEHNILLLVDEAYAGFVFGSPDAVATrallaegpnLLVVGSFSKafglagwrvgYILG 223
|
170
....*....|...
gi 515742593 201 HSDVVAGLVATSN 213
Cdd:pfam00155 224 NAAVISQLRKLAR 236
|
|
| |
