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Conserved domains on  [gi|515915749|ref|WP_017346332|]
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MULTISPECIES: cell division topological specificity factor MinE [Pantoea]

Protein Classification

cell division topological specificity factor MinE( domain architecture ID 10011362)

cell division topological specificity factor MinE prevents cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites, ensuring cell division at the proper site

CATH:  3.30.1070.10
Gene Symbol:  minE
Gene Ontology:  GO:0051301
PubMed:  9393861|11062554
SCOP:  4001444

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 1-87 4.09e-46

cell division topological specificity factor MinE; Reviewed


:

Pssm-ID: 234718  Cd Length: 86  Bit Score: 142.30  E-value: 4.09e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFLSRKKNTANIAKERLQIIVAERRRGDSEPHYLPQLKRDILEVICKYVKIDPEMVTVQLEqRGEDISILELNVT 80
Cdd:PRK00296  1 MSLLDFFRSRKKSTANVAKERLQIIVAHERSSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLD-KDGDISTLELNVT 79


                ....*..
gi 515915749 81 LPEAEEA 87
Cdd:PRK00296 80 LPEAEEK 86
 
Name Accession Description Interval E-value
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 1-87 4.09e-46

cell division topological specificity factor MinE; Reviewed


Pssm-ID: 234718  Cd Length: 86  Bit Score: 142.30  E-value: 4.09e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFLSRKKNTANIAKERLQIIVAERRRGDSEPHYLPQLKRDILEVICKYVKIDPEMVTVQLEqRGEDISILELNVT 80
Cdd:PRK00296  1 MSLLDFFRSRKKSTANVAKERLQIIVAHERSSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLD-KDGDISTLELNVT 79


                ....*..
gi 515915749 81 LPEAEEA 87
Cdd:PRK00296 80 LPEAEEK 86
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 1-86 1.50e-37

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 120.60  E-value: 1.50e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFLSRKKNTANIAKERLQIIVAERRRGDSePHYLPQLKRDILEVICKYVKIDPEMVTVQLEqRGEDISILELNVT 80
Cdd:COG0851   1 MSLLDFFRGRKKSSADVAKERLQLVLAHDRAGLS-PDYLEQLKKEILEVISKYVEIDEDAVEVSLE-REDDLSALEANIP 78


                ....*.
gi 515915749 81 LPEAEE 86
Cdd:COG0851  79 LPRVKR 84
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 1-83 4.81e-32

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 106.67  E-value: 4.81e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749   1 MALLDFFLSRKKNTANIAKERLQIIVAERRRGDSePHYLPQLKRDILEVICKYVKIDPEMVTVQLEQRGeDISILELNVT 80
Cdd:TIGR01215  1 MSLLEFFKSRKKNSAEVAKDRLKLILAHERAQLA-PEYLEELRKEILEVISKYVEIDPEMVEVSLESQG-DMSVLELNIT 78


                 ...
gi 515915749  81 LPE 83
Cdd:TIGR01215 79 LPE 81
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 14-81 7.54e-27

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 92.83  E-value: 7.54e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515915749  14 TANIAKERLQIIVAERRrGDSEPHYLPQLKRDILEVICKYVKIDPEMVTVQLEQRGEDISILELNVTL 81
Cdd:pfam03776  1 SANVAKERLQLILAHDR-ADLSPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDGDVSVLEANIPL 67
 
Name Accession Description Interval E-value
minE PRK00296
cell division topological specificity factor MinE; Reviewed
 1-87 4.09e-46

cell division topological specificity factor MinE; Reviewed


Pssm-ID: 234718  Cd Length: 86  Bit Score: 142.30  E-value: 4.09e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFLSRKKNTANIAKERLQIIVAERRRGDSEPHYLPQLKRDILEVICKYVKIDPEMVTVQLEqRGEDISILELNVT 80
Cdd:PRK00296  1 MSLLDFFRSRKKSTANVAKERLQIIVAHERSSRGEPDYLPQLRKEILEVIAKYVQIDPDKVSVQLD-KDGDISTLELNVT 79


                ....*..
gi 515915749 81 LPEAEEA 87
Cdd:PRK00296 80 LPEAEEK 86
MinE COG0851
Septum formation topological specificity factor MinE [Cell cycle control, cell division, ...
 1-86 1.50e-37

Septum formation topological specificity factor MinE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440612  Cd Length: 84  Bit Score: 120.60  E-value: 1.50e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFLSRKKNTANIAKERLQIIVAERRRGDSePHYLPQLKRDILEVICKYVKIDPEMVTVQLEqRGEDISILELNVT 80
Cdd:COG0851   1 MSLLDFFRGRKKSSADVAKERLQLVLAHDRAGLS-PDYLEQLKKEILEVISKYVEIDEDAVEVSLE-REDDLSALEANIP 78


                ....*.
gi 515915749 81 LPEAEE 86
Cdd:COG0851  79 LPRVKR 84
minE TIGR01215
cell division topological specificity factor MinE; This protein is involved in the process of ...
 1-83 4.81e-32

cell division topological specificity factor MinE; This protein is involved in the process of cell division. This protein prevents the proteins MinC and MinD to inhibit cell division at internal sites, but allows inhibiton at polar sites. This allows for correct cell division at the proper sites. [Cellular processes, Cell division]


Pssm-ID: 188120  Cd Length: 81  Bit Score: 106.67  E-value: 4.81e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749   1 MALLDFFLSRKKNTANIAKERLQIIVAERRRGDSePHYLPQLKRDILEVICKYVKIDPEMVTVQLEQRGeDISILELNVT 80
Cdd:TIGR01215  1 MSLLEFFKSRKKNSAEVAKDRLKLILAHERAQLA-PEYLEELRKEILEVISKYVEIDPEMVEVSLESQG-DMSVLELNIT 78


                 ...
gi 515915749  81 LPE 83
Cdd:TIGR01215 79 LPE 81
MinE pfam03776
Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to ...
 14-81 7.54e-27

Septum formation topological specificity factor MinE; The E. coli minicell locus was shown to code for three gene products (MinC, MinD, and MinE) whose coordinate action is required for proper placement of the division septum. The minE gene codes for a topological specificity factor that, in wild-type cells, prevents the division inhibitor from acting at internal division sites while permitting it to block septation at polar sites.


Pssm-ID: 461046  Cd Length: 67  Bit Score: 92.83  E-value: 7.54e-27
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515915749  14 TANIAKERLQIIVAERRrGDSEPHYLPQLKRDILEVICKYVKIDPEMVTVQLEQRGEDISILELNVTL 81
Cdd:pfam03776  1 SANVAKERLQLILAHDR-ADLSPDYLEQLKNEILEVISKYVEIDEEKVEVQLEQDDGDVSVLEANIPL 67
PRK13989 PRK13989
cell division topological specificity factor MinE; Provisional
 1-84 1.16e-25

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184442  Cd Length: 84  Bit Score: 90.53  E-value: 1.16e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFLSRKKNTANIAKERLQIIVA-ERRRGDSEPHYLPQLKRDILEVICKYVKIDPEMVTVQLEqRGEDISILELNV 79
Cdd:PRK13989  1 MSILSFLLGEKKKTASVAKERLQIIIAhERVGGRQPPDYLPALQKELVAVISKYVKISPDDIRVSLE-RQDNLEVLEVKI 79


                ....*
gi 515915749 80 TLPEA 84
Cdd:PRK13989 80 ELPQA 84
PRK13988 PRK13988
cell division topological specificity factor MinE; Provisional
 3-66 2.18e-12

cell division topological specificity factor MinE; Provisional


Pssm-ID: 184441  Cd Length: 97  Bit Score: 57.08  E-value: 2.18e-12
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515915749  3 LLDFFLSRKKNTANIAKERLQIIVAERRRGDSePHYLPQLKRDILEVICKYVKIDPEMVTVQLE 66
Cdd:PRK13988  6 LLEKLFGRQPASASTARERLQLVLAHDRADLS-PELLEQMRKEILEVVARYVEIDPEEGEVSLE 68
PRK13987 PRK13987
cell division topological specificity factor MinE; Provisional
 1-82 3.28e-10

cell division topological specificity factor MinE; Provisional


Pssm-ID: 237579  Cd Length: 91  Bit Score: 51.59  E-value: 3.28e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFlSRKKNTANIAKERLQIIVAERRrGDSEPHYLPQLKRDILEVICKYVKIDPEMVTVQL--EQRGEDISILELN 78
Cdd:PRK13987  1 MDLFKFF-SKKPTSKDVAKERLKLILIHDR-GDISPDVLEMIKEDILKVISKYVEIDNEDVDIKMtkSEEIDEGMSPALI 78


                ....
gi 515915749 79 VTLP 82
Cdd:PRK13987 79 ANIP 82
PRK13991 PRK13991
cell division topological specificity factor MinE; Provisional
 1-81 1.02e-07

cell division topological specificity factor MinE; Provisional


Pssm-ID: 172493  Cd Length: 87  Bit Score: 45.26  E-value: 1.02e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515915749  1 MALLDFFLSRKK-NTANIAKERLQIIVAERRRGDSePHYLPQLKRDILEVICKYVK-IDPEMVTVQLeQRGEDISILELN 78
Cdd:PRK13991  1 MSFLDGLFGRKRdSSSELAKQRLLTVLVHDRVKLT-PEMMEQMKADLAEVIKRYVPaIDAEAIEVTL-SRGEAHDHLKAD 78


                ...
gi 515915749 79 VTL 81
Cdd:PRK13991 79 IPL 81
PRK13990 PRK13990
cell division topological specificity factor MinE; Provisional
 6-61 1.30e-05

cell division topological specificity factor MinE; Provisional


Pssm-ID: 172492  Cd Length: 90  Bit Score: 39.72  E-value: 1.30e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515915749  6 FFLSRKKNTANIAKERLQIIVAERRR------GDSEPHYLPQLKRDILEVICKYVKIDPEMV 61
Cdd:PRK13990  6 FGLSKKQQSASVAKERLQIIVAHQRSelhprsSKISSHLLAELKDEIIEVVKKYVALSEENI 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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