NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|515927287|ref|WP_017357870|]
View 

MULTISPECIES: methyl-accepting chemotaxis protein [Bacillus]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
16-561 8.50e-78

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 254.95  E-value: 8.50e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  16 ILFVSILGFSSFIYYKTDQSYKALLTKEVKLYQTSLELEALLQKQEAQIKTYVVVQDAENLQKIEQTYEEINKKTTEASK 95
Cdd:COG0840   16 LLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLAL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  96 MSTVKQAKNLLDQISEKNYLYYTSTNRLFNSLNMQNQKEFNTRLSQELQPIEQEIHTFTKEFAQTQLKQRDQKISQLNEE 175
Cdd:COG0840   96 LALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALA 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 176 SNQLLLTLILVSAAIIVGFLVIGTRFVHR-MTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQL 254
Cdd:COG0840  176 AAALALALLAAALLALVALAIILALLLSRsITRPLRELLEVLERIAEGDLT-VRIDVDSKDEIGQLADAFNRMIENLREL 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 255 ILQVQNGSRQLAdsaaqfeetisqtiSASEQTSSSIEQVSEASREQSDAVGKVASAIQEVSTGMHNAAEHTSDVSGHSIS 334
Cdd:COG0840  255 VGQVRESAEQVA--------------SASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 335 VTEKAEEGASLIQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAV 414
Cdd:COG0840  321 ASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAV 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 415 VADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTE 494
Cdd:COG0840  401 VADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASE 480

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515927287 495 QISASTEEISQTIgvieegakrnseetEYMSAAVEESLAANEEMKAAAEDLKSLSQSLKTSISSFKI 561
Cdd:COG0840  481 EQSAGTEEVNQAI--------------EQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
16-561 8.50e-78

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 254.95  E-value: 8.50e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  16 ILFVSILGFSSFIYYKTDQSYKALLTKEVKLYQTSLELEALLQKQEAQIKTYVVVQDAENLQKIEQTYEEINKKTTEASK 95
Cdd:COG0840   16 LLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLAL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  96 MSTVKQAKNLLDQISEKNYLYYTSTNRLFNSLNMQNQKEFNTRLSQELQPIEQEIHTFTKEFAQTQLKQRDQKISQLNEE 175
Cdd:COG0840   96 LALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALA 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 176 SNQLLLTLILVSAAIIVGFLVIGTRFVHR-MTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQL 254
Cdd:COG0840  176 AAALALALLAAALLALVALAIILALLLSRsITRPLRELLEVLERIAEGDLT-VRIDVDSKDEIGQLADAFNRMIENLREL 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 255 ILQVQNGSRQLAdsaaqfeetisqtiSASEQTSSSIEQVSEASREQSDAVGKVASAIQEVSTGMHNAAEHTSDVSGHSIS 334
Cdd:COG0840  255 VGQVRESAEQVA--------------SASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 335 VTEKAEEGASLIQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAV 414
Cdd:COG0840  321 ASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAV 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 415 VADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTE 494
Cdd:COG0840  401 VADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASE 480

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515927287 495 QISASTEEISQTIgvieegakrnseetEYMSAAVEESLAANEEMKAAAEDLKSLSQSLKTSISSFKI 561
Cdd:COG0840  481 EQSAGTEEVNQAI--------------EQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 285-553 3.52e-53

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 181.72  E-value: 3.52e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   285 QTSSSIEQVSEASREQSDAVGKVASAIQEVSTGMHNAAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEHH 364
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   365 STMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDT 444
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   445 ERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTEQISASTEEISQTIGVIEEGAKRNseeteym 524
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQET------- 233

                          250       260
                   ....*....|....*....|....*....
gi 515927287   525 SAAVEESLAANEEMKAAAEDLKSLSQSLK 553
Cdd:smart00283 234 AAMSEEISAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 312-510 4.87e-48

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 165.87  E-value: 4.87e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 312 QEVSTGMHNAAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQT 391
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 392 NLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQS 471
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 515927287 472 FQEILAAIRDISMKAEELSATTEQISASTEEISQTIGVI 510
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEI 199
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 336-507 9.73e-36

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 131.79  E-value: 9.73e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  336 TEKAEEGASLIQQFVKQMSSIKESVNEhhstmanvqvqftgIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAVV 415
Cdd:pfam00015   8 SEEAQDGGKEVANVVGQMEQIAQSSKK--------------ISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  416 ADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTEQ 495
Cdd:pfam00015  74 ADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDE 153

                         170
                  ....*....|..
gi 515927287  496 ISASTEEISQTI 507
Cdd:pfam00015 154 QSAGIDQVNQAV 165
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
144-519 9.37e-30

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 123.14  E-value: 9.37e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 144 QPIEQEIHTFTKEFAQTQLKQR---DQKISQLNEESNQLLLTLILVSAAIIVGFLVIGTRFVHRMTKPIVSVTHAARRMA 220
Cdd:PRK15041 154 QPTQGYQDGFEKQYVAYMEQNDrlyDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIA 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 221 DGDLtLEEIEVTSKNEIGQLGTAFNQMTAHLRQLILQVQNGSRQLADSAAQFEETISQTISASEQTSSSIEQVseasreq 300
Cdd:PRK15041 234 GGDL-VKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEET------- 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 301 sdavgkvASAIQEVSTGMHNAAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEhhstmanvqvqftgIQDL 380
Cdd:PRK15041 306 -------AASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQK--------------IADI 364

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 381 LGNIHAIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAE 460
Cdd:PRK15041 365 ISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAE 444

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515927287 461 GVKVSQLSEQSFQEILAA-------IRDISMKAEELSATTEQISASTEEISQTIGVIEEGAKRNSE 519
Cdd:PRK15041 445 IVSAVTRVTDIMGEIASAsdeqsrgIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTE 510
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 346-558 1.17e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   346 IQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGfavVADEVRKLAEE 425
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ---LEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   426 SSQLTDQISQLLANVNKDTE---RSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTEQISASTEE 502
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEelaEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA 835

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 515927287   503 ISQTIGVIEEGAKRNSEETEYMSAAVEESLAANEEMKAAAEDLKSLSQSLKTSISS 558
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
16-561 8.50e-78

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 254.95  E-value: 8.50e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  16 ILFVSILGFSSFIYYKTDQSYKALLTKEVKLYQTSLELEALLQKQEAQIKTYVVVQDAENLQKIEQTYEEINKKTTEASK 95
Cdd:COG0840   16 LLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLAL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  96 MSTVKQAKNLLDQISEKNYLYYTSTNRLFNSLNMQNQKEFNTRLSQELQPIEQEIHTFTKEFAQTQLKQRDQKISQLNEE 175
Cdd:COG0840   96 LALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALA 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 176 SNQLLLTLILVSAAIIVGFLVIGTRFVHR-MTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQL 254
Cdd:COG0840  176 AAALALALLAAALLALVALAIILALLLSRsITRPLRELLEVLERIAEGDLT-VRIDVDSKDEIGQLADAFNRMIENLREL 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 255 ILQVQNGSRQLAdsaaqfeetisqtiSASEQTSSSIEQVSEASREQSDAVGKVASAIQEVSTGMHNAAEHTSDVSGHSIS 334
Cdd:COG0840  255 VGQVRESAEQVA--------------SASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 335 VTEKAEEGASLIQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAV 414
Cdd:COG0840  321 ASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAV 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 415 VADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTE 494
Cdd:COG0840  401 VADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASE 480

                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 515927287 495 QISASTEEISQTIgvieegakrnseetEYMSAAVEESLAANEEMKAAAEDLKSLSQSLKTSISSFKI 561
Cdd:COG0840  481 EQSAGTEEVNQAI--------------EQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 285-553 3.52e-53

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 181.72  E-value: 3.52e-53
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   285 QTSSSIEQVSEASREQSDAVGKVASAIQEVSTGMHNAAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEHH 364
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   365 STMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDT 444
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   445 ERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTEQISASTEEISQTIGVIEEGAKRNseeteym 524
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQET------- 233

                          250       260
                   ....*....|....*....|....*....
gi 515927287   525 SAAVEESLAANEEMKAAAEDLKSLSQSLK 553
Cdd:smart00283 234 AAMSEEISAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 312-510 4.87e-48

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 165.87  E-value: 4.87e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 312 QEVSTGMHNAAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQT 391
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 392 NLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQS 471
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 515927287 472 FQEILAAIRDISMKAEELSATTEQISASTEEISQTIGVI 510
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEI 199
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 336-507 9.73e-36

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 131.79  E-value: 9.73e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  336 TEKAEEGASLIQQFVKQMSSIKESVNEhhstmanvqvqftgIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAVV 415
Cdd:pfam00015   8 SEEAQDGGKEVANVVGQMEQIAQSSKK--------------ISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVV 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  416 ADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTEQ 495
Cdd:pfam00015  74 ADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDE 153

                         170
                  ....*....|..
gi 515927287  496 ISASTEEISQTI 507
Cdd:pfam00015 154 QSAGIDQVNQAV 165
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
144-519 9.37e-30

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 123.14  E-value: 9.37e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 144 QPIEQEIHTFTKEFAQTQLKQR---DQKISQLNEESNQLLLTLILVSAAIIVGFLVIGTRFVHRMTKPIVSVTHAARRMA 220
Cdd:PRK15041 154 QPTQGYQDGFEKQYVAYMEQNDrlyDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIA 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 221 DGDLtLEEIEVTSKNEIGQLGTAFNQMTAHLRQLILQVQNGSRQLADSAAQFEETISQTISASEQTSSSIEQVseasreq 300
Cdd:PRK15041 234 GGDL-VKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEET------- 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 301 sdavgkvASAIQEVSTGMHNAAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEhhstmanvqvqftgIQDL 380
Cdd:PRK15041 306 -------AASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQK--------------IADI 364

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 381 LGNIHAIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAE 460
Cdd:PRK15041 365 ISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAE 444

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515927287 461 GVKVSQLSEQSFQEILAA-------IRDISMKAEELSATTEQISASTEEISQTIGVIEEGAKRNSE 519
Cdd:PRK15041 445 IVSAVTRVTDIMGEIASAsdeqsrgIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTE 510
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 72-516 9.81e-29

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 120.11  E-value: 9.81e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  72 DAENLQKIEQTYEEINKKTTEASKMSTVKQAKNLLDQ---------ISEKNYLYYTSTNRLFNSLNMQNQKEFntrLSQE 142
Cdd:PRK15048  77 DSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLpemvatsrnIDEKYKNYYTALTELIDYLDYGNTGAY---FAQP 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 143 LQPIEQEIHTFTKEFAQTQLKQRDQKISQLNEESNQLLLTLILVSAAIIVGFLVIGTRFVHRMTKPIVSVTHAARRMADG 222
Cdd:PRK15048 154 TQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGG 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 223 DLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQLILQVQNGSRQLADSAAQFEETISQTISASEQTSSSIEQVSeASREQSD 302
Cdd:PRK15048 234 NLA-NTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETA-ASMEQLT 311

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 303 AVGKvasaiqevstgmhNAAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEhhstmanvqvqftgIQDLLG 382
Cdd:PRK15048 312 ATVK-------------QNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKK--------------IADIIS 364

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 383 NIHAIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLL----ANVNKDT---ERSSQSMTKVE 455
Cdd:PRK15048 365 VIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIedsvSRVDTGSvlvESAGETMNNIV 444

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 515927287 456 RDVAE-----GVKVSQLSEQSfqeilAAIRDISMKAEELSATTEQISASTEEISQTIGVIEEGAKR 516
Cdd:PRK15048 445 NAVTRvtdimGEIASASDEQS-----RGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASR 505
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
94-548 5.09e-27

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 114.78  E-value: 5.09e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  94 SKMSTVKQAKNLLDQISEKNYlyytstNRLFNSLNMQNQKEFNTRLSQELQ-PIEQEIHTFTKEFAQTQLK-----QRDQ 167
Cdd:PRK09793 105 MAMTAGNEHVRALQKETEKSF------ARWHNDLEHQATWLESNQLSDFLTaPVQGSQNAFDVNFEAWQLEinhvlEAAS 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 168 KISQLNEESNQLLLTLILVSAAIIVGFLVIGTRfvHRMTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQM 247
Cdd:PRK09793 179 AQSQRNYQISALVFISMIIVAAIYISSALWWTR--KMIVQPLAIIGSHFDSIAAGNLA-RPIAVYGRNEITAIFASLKTM 255

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 248 TAHLRQLILQVQNGSRQLadsaaqfEETISQTISASEQTSSSIEQvseasreQSDAVGKVASAIQEVSTGMHNAAEHTSD 327
Cdd:PRK09793 256 QQALRGTVSDVRKGSQEM-------HIGIAEIVAGNNDLSSRTEQ-------QAASLAQTAASMEQLTATVGQNADNARQ 321

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 328 VSGHSISVTEKAEEGASliqqfvkQMSSIKesvnehhSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGE 407
Cdd:PRK09793 322 ASELAKNAATTAQAGGV-------QVSTMT-------HTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGE 387

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 408 HGRGFAVVADEVRKLAEESSQLTDQISQLLanvnkdtersSQSMTKVErdvaEGVKVSQLSEQSFQEILAAIRDISMKAE 487
Cdd:PRK09793 388 QGRGFAVVAGEVRNLASRSAQAAKEIKGLI----------EESVNRVQ----QGSKLVNNAAATMTDIVSSVTRVNDIMG 453

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 515927287 488 ELSATTEQISASTEEISQTIGVIEEGAKRNseeteymSAAVEESLAANEEMKAAAEDLKSL 548
Cdd:PRK09793 454 EIASASEEQRRGIEQVAQAVSQMDQVTQQN-------ASLVEEAAVATEQLANQADHLSSR 507
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 206-251 1.10e-13

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 65.16  E-value: 1.10e-13
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 515927287 206 TKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHL 251
Cdd:cd06225    1 TRPLRRLTEAARRIAEGDLD-VRVPVRSKDEIGELARAFNQMAERL 45
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 178-282 8.47e-13

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 70.38  E-value: 8.47e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 178 QLLLTLILVSAAIIVGFLVI--GTRFVHRMTKPIVSVTHAARRMADGDLTLeEIEVTSKNEIGQLGTAFNQMTAHLRQli 255
Cdd:COG5000    4 QILFLLLLLLIALLLLLLALwlALLLARRLTRPLRRLAEATRAVAAGDLSV-RLPVTGDDEIGELARAFNRMTDQLKE-- 80

                         90       100
                 ....*....|....*....|....*..
gi 515927287 256 lqvqngSRQLADSAAQFEETISQTISA 282
Cdd:COG5000   81 ------QREELEERRRYLETILENLPA 101
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
203-255 1.83e-11

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 59.18  E-value: 1.83e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 515927287   203 HRMTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQLI 255
Cdd:smart00304   1 RRLLRPLRRLAEAAQRIADGDLT-VRLPVDGRDEIGELARAFNEMADRLEETI 52
HAMP pfam00672
HAMP domain;
200-253 3.01e-11

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 58.40  E-value: 3.01e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 515927287  200 RFVHRMTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQ 253
Cdd:pfam00672   1 LLARRILRPLRRLAEAARRIASGDLD-VRLPVSGRDEIGELARAFNQMAERLRE 53
YesM COG2972
Sensor histidine kinase YesM [Signal transduction mechanisms];
170-268 4.19e-09

Sensor histidine kinase YesM [Signal transduction mechanisms];


Pssm-ID: 442211 [Multi-domain]  Cd Length: 445  Bit Score: 58.88  E-value: 4.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 170 SQLNEESNQLLLTLILVSAAIIVGFLVIGTRFVHRMTKPIVSVTHAARRMADGDLTleEIEVTSKNEIGQLGTAFNQMTA 249
Cdd:COG2972  146 SELFRGLFSLRRLILLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV--RLEVSGNDEIGILARSFNEMVE 223

                         90
                 ....*....|....*....
gi 515927287 250 HLRQLILQVQNGSRQLADS 268
Cdd:COG2972  224 RIKELIEEVYELELEKKEA 242
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
1-554 1.75e-07

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 53.96  E-value: 1.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   1 MRLKNQFLFGLIVICILFVSILGFSSFIYYKTDQSYKALLTKEVKLYQTSLELEALLQKQEAQIKTYVVVQDAENLQKIE 80
Cdd:COG2770   32 SLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLL 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287  81 QTYEEINKKTTEASKMSTVKQAKNLLDQISEKNYLYYTSTNRLFNSLNMQNQKEFNTRLSQELQPIEQEIHTFTKEFAQT 160
Cdd:COG2770  112 LLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAIAALLAALL 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 161 QLKQRDQKISQLNEESNQLLLTLILVSAAIIVGFLVIGTRFVHRMTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQL 240
Cdd:COG2770  192 LLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLD-VRIPVSRKDEIGEL 270

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 241 GTAFNQMTAHLRQLILQVQNGSRQLADSAAQFEETISQTISASEQTSSSIEQVSEASREQSDAVGKVASAIQEVSTGMHN 320
Cdd:COG2770  271 ARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADL 350

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 321 AAEHTSDVSGHSISVTEKAEEGASLIQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAI 400
Cdd:COG2770  351 LLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAA 430

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 401 EAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIR 480
Cdd:COG2770  431 AEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELL 510

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 515927287 481 DISMKAEELSATTEQISASTEEISQTIGVIEEGAKRNSEETEYMSAAVEESLAANEEMKAAAEDLKSLSQSLKT 554
Cdd:COG2770  511 LLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLALLLALAAVEAAALLLAALLLAAVAALLELAA 584
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 182-511 1.26e-06

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 51.04  E-value: 1.26e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 182 TLILVSAAIIVGFLVIGTRFVHRMTKPIVSVTHAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQLILQVQNG 261
Cdd:COG3850  119 LALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFD-ARVPVSGRDELGTLARAFNRMADELQELYAELEEE 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 262 SRQLADSAAQFEETISQTISASEQTSSSIEQVSEASREQSDAVGKVASAIQEVSTGMHNAAEHTSDVSGHSISVTEKAEE 341
Cdd:COG3850  198 EELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASA 277

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 342 gASLIQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRK 421
Cdd:COG3850  278 -LLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEAA 356

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 422 LAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTEQISASTE 501
Cdd:COG3850  357 AAGAALAAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGGVAGEGGLVVLIVSIIAGGEAIARGEAL 436

                        330
                 ....*....|
gi 515927287 502 EISQTIGVIE 511
Cdd:COG3850  437 AARGLAAAAA 446
PRK10935 PRK10935
nitrate/nitrite two-component system sensor histidine kinase NarQ;
183-254 3.17e-05

nitrate/nitrite two-component system sensor histidine kinase NarQ;


Pssm-ID: 236800 [Multi-domain]  Cd Length: 565  Bit Score: 46.77  E-value: 3.17e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515927287 183 LILVSAAIIVGFLVI------GTRFVHR-MTKPIVSVTHAARRMADGDLTLEEIEVTSKNEIGQLGTAFNQMTAHLRQL 254
Cdd:PRK10935 147 LILLAAISLLGLILIltlvffTVRFTRRqVVAPLNQLVTASQQIEKGQFDHIPLDTTLPNELGLLAKAFNQMSSELHKL 225
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 233-349 3.47e-04

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 42.66  E-value: 3.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   233 SKNEIGQLGTAFNQMTAHLRQLILQVQNGSRQLADSAAQFEETISQTISASEQTSSSIEQVSEASREQSDAVGKVASAIQ 312
Cdd:smart00283 145 SAKEIESLIKEIQEETNEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAID 224

                           90       100       110
                   ....*....|....*....|....*....|....*..
gi 515927287   313 EVSTGMHNAAEHTSDVSGHSISVTEKAEEGASLIQQF 349
Cdd:smart00283 225 EIAQVTQETAAMSEEISAAAEELSGLAEELDELVERF 261
envZ PRK09467
osmolarity sensor protein; Provisional
 174-254 8.63e-04

osmolarity sensor protein; Provisional


Pssm-ID: 236531 [Multi-domain]  Cd Length: 435  Bit Score: 41.82  E-value: 8.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 174 EESNQLLLTLILvsaaIIVGFLVI--GTRFVHRMTKPIVSVTHAARRMADGDL--------TLEEIEVTSkneigqlgtA 243
Cdd:PRK09467 148 HQGDFSPLFRYT----LAIGLLSVagGWLFIRIQNRPLVALEHAALQVGKGEIppplreygASEVRSVTR---------A 214

                         90
                 ....*....|.
gi 515927287 244 FNQMTAHLRQL 254
Cdd:PRK09467 215 FNQMAAGIKQL 225
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 346-558 1.17e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   346 IQQFVKQMSSIKESVNEHHSTMANVQVQFTGIQDLLGNIHAIADQTNLLALNAAIEAARAGEHGRGfavVADEVRKLAEE 425
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ---LEERIAQLSKE 755

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287   426 SSQLTDQISQLLANVNKDTE---RSSQSMTKVERDVAEGVKVSQLSEQSFQEILAAIRDISMKAEELSATTEQISASTEE 502
Cdd:TIGR02168  756 LTELEAEIEELEERLEEAEEelaEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAA 835

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 515927287   503 ISQTIGVIEEGAKRNSEETEYMSAAVEESLAANEEMKAAAEDLKSLSQSLKTSISS 558
Cdd:TIGR02168  836 TERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891
PRK10604 PRK10604
sensor protein RstB; Provisional
 214-270 1.68e-03

sensor protein RstB; Provisional


Pssm-ID: 236724 [Multi-domain]  Cd Length: 433  Bit Score: 41.13  E-value: 1.68e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 515927287 214 HAARRMADGDLTlEEIEVTSKNEIGQLGTAFNQMTAHLRQLIlqvqNGSRQLADSAA 270
Cdd:PRK10604 169 AAAQRLGDGHLA-ERIHFDEGSSLERLGVAFNQMADNINALI----ASKKQLIDGIA 220
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 396-553 7.62e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 39.07  E-value: 7.62e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 396 LNAAIEAARAGEHGRGFAVVADEVRKLAEESSQLTDQISQLLANVNKDTERSSQSMTKVERDVAEGV-------KVSQLS 468
Cdd:PLN03229 576 IKEKMEALKAEVASSGASSGDELDDDLKEKVEKMKKEIELELAGVLKSMGLEVIGVTKKNKDTAEQTpppnlqeKIESLN 655

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515927287 469 EQSFQEILAAIR--DISMKAEELSATTEQISASTE-EISQTIGVIEEGAKRNSEETEYMSAAVEESLAANEEMKAAAEDL 545
Cdd:PLN03229 656 EEINKKIERVIRssDLKSKIELLKLEVAKASKTPDvTEKEKIEALEQQIKQKIAEALNSSELKEKFEELEAELAAARETA 735


                 ....*...
gi 515927287 546 KSLSQSLK 553
Cdd:PLN03229 736 AESNGSLK 743
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH