NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|515955408|ref|WP_017385991|]
View 

MULTISPECIES: D-amino acid dehydrogenase [Acinetobacter]

Protein Classification

D-amino acid dehydrogenase( domain architecture ID 11485893)

D-amino acid dehydrogenase catalyzes the oxidative deamination of D-amino acids to yield the corresponding 2-oxo acids; also able to oxidize D-amino acid analogs; similar to Escherichia coli str. K-12 DadA

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 1-414 0e+00

D-amino acid dehydrogenase small subunit; Provisional


:

Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 857.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETSFANGGQLSACNAEVWNQKATVIKGFKWMRQKDAPLLLNP 80
Cdd:PRK12409   1 MSHIAVIGAGITGVTTAYALAQRGYQVTVFDRHRYAAMETSFANGGQLSASNAEVWNHWATVLKGLKWMLRKDAPLLLNP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  81 SFSLHKYSWLVEFLSHIKNYEANTIETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGT 160
Cdd:PRK12409  81 KPSWHKYSWLAEFLAHIPNYRANTIETVRLAIAARKHLFDIAEREGIDFDLERRGILHIYHDKAGFDHAKRVNALLAEGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 161 LERYSVSPDEMKTIEPSLTGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVTCQPSAEH 240
Cdd:PRK12409 161 LERRAVTPEEMRAIEPTLTGEYYGGYYTPSDSTGDIHKFTTGLAAACARLGVQFRYGQEVTSIKTDGGGVVLTVQPSAEH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 241 PylvesdNIQLEGDVLVVCGGVGSYQLADMIGERVNVYPVKGYSITVQLKDEHSVNNAPWVSLLDESAKIVTSRLGKDRL 320
Cdd:PRK12409 241 P------SRTLEFDGVVVCAGVGSRALAAMLGDRVNVYPVKGYSITVNLDDEASRAAAPWVSLLDDSAKIVTSRLGADRF 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 321 RVAGTAEFNGYNRDIRADRIQPLVNWVNRNF-DISTEHVVPWAGLRPMMPNMLPVVKQSKQPRVFYNTGHGHLGWTLSAA 399
Cdd:PRK12409 315 RVAGTAEFNGYNRDIRADRIRPLVDWVRRNFpDVSTRRVVPWAGLRPMMPNMMPRVGRGRRPGVFYNTGHGHLGWTLSAA 394

                        410
                 ....*....|....*
gi 515955408 400 TAVLVGQDIAQKYPA 414
Cdd:PRK12409 395 TADLVAQVVAQKLPA 409
 
Name Accession Description Interval E-value
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 1-414 0e+00

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 857.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETSFANGGQLSACNAEVWNQKATVIKGFKWMRQKDAPLLLNP 80
Cdd:PRK12409   1 MSHIAVIGAGITGVTTAYALAQRGYQVTVFDRHRYAAMETSFANGGQLSASNAEVWNHWATVLKGLKWMLRKDAPLLLNP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  81 SFSLHKYSWLVEFLSHIKNYEANTIETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGT 160
Cdd:PRK12409  81 KPSWHKYSWLAEFLAHIPNYRANTIETVRLAIAARKHLFDIAEREGIDFDLERRGILHIYHDKAGFDHAKRVNALLAEGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 161 LERYSVSPDEMKTIEPSLTGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVTCQPSAEH 240
Cdd:PRK12409 161 LERRAVTPEEMRAIEPTLTGEYYGGYYTPSDSTGDIHKFTTGLAAACARLGVQFRYGQEVTSIKTDGGGVVLTVQPSAEH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 241 PylvesdNIQLEGDVLVVCGGVGSYQLADMIGERVNVYPVKGYSITVQLKDEHSVNNAPWVSLLDESAKIVTSRLGKDRL 320
Cdd:PRK12409 241 P------SRTLEFDGVVVCAGVGSRALAAMLGDRVNVYPVKGYSITVNLDDEASRAAAPWVSLLDDSAKIVTSRLGADRF 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 321 RVAGTAEFNGYNRDIRADRIQPLVNWVNRNF-DISTEHVVPWAGLRPMMPNMLPVVKQSKQPRVFYNTGHGHLGWTLSAA 399
Cdd:PRK12409 315 RVAGTAEFNGYNRDIRADRIRPLVDWVRRNFpDVSTRRVVPWAGLRPMMPNMMPRVGRGRRPGVFYNTGHGHLGWTLSAA 394

                        410
                 ....*....|....*
gi 515955408 400 TAVLVGQDIAQKYPA 414
Cdd:PRK12409 395 TADLVAQVVAQKLPA 409
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-409 1.20e-81

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 254.83  E-value: 1.20e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRHlYPAMETSFANGGQLSACNAEVWNQkatvikgfkwmrqkdaplllnp 80
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERG-RPGSGASGRNAGQLRPGLAALADR---------------------- 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  81 sfslhkyswlveflshiknyeantiETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGT 160
Cdd:COG0665   59 -------------------------ALVRLAREALDLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALG 113

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 161 LERYSVSPDEMKTIEPSL-TGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVtcqpsae 239
Cdd:COG0665  114 LPVELLDAAELREREPGLgSPDYAGGLYDPDDGHVDPAKLVRALARAARAAGVRIREGTPVTGLEREGGRVTG------- 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 240 hpylVESDNIQLEGDVLVVCGGVGSYQLADMIGERVNVYPVKGYSITVQLKDEhsvnnAPWVSLLDESaKIVTSRLGKDR 319
Cdd:COG0665  187 ----VRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPD-----LPLRPVLDDT-GVYLRPTADGR 256

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 320 LRVAGTAEFNGYNRDIRADRIQPLVNWVNRNF----DISTEHVvpWAGLRPMMPNMLPVVKQS-KQPRVFYNTGHGHLGW 394
Cdd:COG0665  257 LLVGGTAEPAGFDRAPTPERLEALLRRLRRLFpalaDAEIVRA--WAGLRPMTPDGLPIIGRLpGAPGLYVATGHGGHGV 334

                        410
                 ....*....|....*
gi 515955408 395 TLSAATAVLVGQDIA 409
Cdd:COG0665  335 TLAPAAGRLLADLIL 349
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 3-406 2.38e-60

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 199.16  E-value: 2.38e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408    3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETSFANGGQLsacnaevwnqkatvikgfkwmrqkdaplllnpsf 82
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGASGRNAGLI---------------------------------- 46

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   83 slhkYSWLveflshiknYEANTIETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGTLE 162
Cdd:pfam01266  47 ----HPGL---------RYLEPSELARLALEALDLWEELEEELGIDCGFRRCGVLVLARDEEEEALEKLLAALRRLGVPA 113

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  163 RYsVSPDEMKTIEPsLTGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVTCQPSAehpy 242
Cdd:pfam01266 114 EL-LDAEELRELEP-LLPGLRGGLFYPDGGHVDPARLLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGEA---- 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  243 lvesdniqlegDVLVVCGGVGSyQLADMIGERVNVYPVKGYSITVQLKDEHSVNNAPWVSLLDESAKIVTSRLGkDRLRV 322
Cdd:pfam01266 188 -----------DAVVNAAGAWA-DLLALPGLRLPVRPVRGQVLVLEPLPEALLILPVPITVDPGRGVYLRPRAD-GRLLL 254

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  323 AGTAEFNGYNR-DIRADRIQPLVNWVNRNFDISTEHVVPWAGLRPMmPNMLPVVKQSKQPRVFYNTGHGHLGWTLSAATA 401
Cdd:pfam01266 255 GGTDEEDGFDDpTPDPEEIEELLEAARRLFPALADIERAWAGLRPL-PDGLPIIGRPGSPGLYLATGHGGHGLTLAPGIG 333


                  ....*
gi 515955408  402 VLVGQ 406
Cdd:pfam01266 334 KLLAE 338
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 18-411 8.92e-26

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 106.68  E-value: 8.92e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   18 YELSQLGYQVTVIDRHLyPAMETSFANGGQLSAcNAEVWNQKATVIkgfkwmrqkdaplllnpsfslhkyswlveflshi 97
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDP-MGGGASWAAAGMLAP-HAECEYAEDPLF---------------------------------- 44

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   98 knyeantietvRLALLARKR----LFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGTLERYSVSPDEMKT 173
Cdd:TIGR02352  45 -----------DLALESLRLypewLEALKELTGLDTGYHQCGTLVVAFDEDDVEHLRQLADLQSATGMEVEWLSGRALRR 113

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  174 IEPSLTGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVvtcqpsaehpyLVESDNIQLEG 253
Cdd:TIGR02352 114 LEPYLSGGIRGAVFYPDDAHVDPRALLKALEKALEKLGVEIIEHTEVQHIEIRGEKVT-----------AIVTPSGDVQA 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  254 DVLVVCGGVGSYQLadmigERVNVYPVKGYSITVQLKDEHSVNNAPWVSLLDESAKIVTSRlgKDRLRVAGTAEFNGYNR 333
Cdd:TIGR02352 183 DQVVLAAGAWAGEL-----LPLPLRPVRGQPLRLEAPAVPLLNRPLRAVVYGRRVYIVPRR--DGRLVVGATMEESGFDT 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  334 DIRADRIQPLVNWVnrnfdistEHVVP----------WAGLRPMMPNMLPVV-KQSKQPRVFYNTGHGHLGWTLSAATAV 402
Cdd:TIGR02352 256 TPTLGGIKELLRDA--------YTILPalkearlletWAGLRPGTPDNLPYIgEHPEDRRLLIATGHYRNGILLAPATAE 327


                  ....*....
gi 515955408  403 LVGQDIAQK 411
Cdd:TIGR02352 328 VIADLILGK 336
 
Name Accession Description Interval E-value
PRK12409 PRK12409
D-amino acid dehydrogenase small subunit; Provisional
 1-414 0e+00

D-amino acid dehydrogenase small subunit; Provisional


Pssm-ID: 237093 [Multi-domain]  Cd Length: 410  Bit Score: 857.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETSFANGGQLSACNAEVWNQKATVIKGFKWMRQKDAPLLLNP 80
Cdd:PRK12409   1 MSHIAVIGAGITGVTTAYALAQRGYQVTVFDRHRYAAMETSFANGGQLSASNAEVWNHWATVLKGLKWMLRKDAPLLLNP 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  81 SFSLHKYSWLVEFLSHIKNYEANTIETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGT 160
Cdd:PRK12409  81 KPSWHKYSWLAEFLAHIPNYRANTIETVRLAIAARKHLFDIAEREGIDFDLERRGILHIYHDKAGFDHAKRVNALLAEGG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 161 LERYSVSPDEMKTIEPSLTGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVTCQPSAEH 240
Cdd:PRK12409 161 LERRAVTPEEMRAIEPTLTGEYYGGYYTPSDSTGDIHKFTTGLAAACARLGVQFRYGQEVTSIKTDGGGVVLTVQPSAEH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 241 PylvesdNIQLEGDVLVVCGGVGSYQLADMIGERVNVYPVKGYSITVQLKDEHSVNNAPWVSLLDESAKIVTSRLGKDRL 320
Cdd:PRK12409 241 P------SRTLEFDGVVVCAGVGSRALAAMLGDRVNVYPVKGYSITVNLDDEASRAAAPWVSLLDDSAKIVTSRLGADRF 314

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 321 RVAGTAEFNGYNRDIRADRIQPLVNWVNRNF-DISTEHVVPWAGLRPMMPNMLPVVKQSKQPRVFYNTGHGHLGWTLSAA 399
Cdd:PRK12409 315 RVAGTAEFNGYNRDIRADRIRPLVDWVRRNFpDVSTRRVVPWAGLRPMMPNMMPRVGRGRRPGVFYNTGHGHLGWTLSAA 394

                        410
                 ....*....|....*
gi 515955408 400 TAVLVGQDIAQKYPA 414
Cdd:PRK12409 395 TADLVAQVVAQKLPA 409
PRK00711 PRK00711
D-amino acid dehydrogenase;
3-414 1.87e-105

D-amino acid dehydrogenase;


Pssm-ID: 234819 [Multi-domain]  Cd Length: 416  Bit Score: 317.90  E-value: 1.87e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETSFANGGQLSACNAEVWNQKATVIKGFKWMRQKDAPLLLNPSF 82
Cdd:PRK00711   2 RVVVLGSGVIGVTSAWYLAQAGHEVTVIDRQPGPALETSFANAGQISPGYAAPWAAPGVPLKAIKWLFQRHAPLAIRPDG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  83 SLHKYSWLVEFLSHI--KNYEANTIETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYE-IAKQVnnvlnkG 159
Cdd:PRK00711  82 DPFQLRWMWQMLRNCtaSRYAVNKSRMVRLAEYSRDCLKALRAETGIQYEGRQGGTLQLFRTQQQLDaAAKDI------A 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 160 TLERYSV-----SPDEMKTIEPSLTG--DYF-GGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVV 231
Cdd:PRK00711 156 VLEEAGVpyellDRDELAAVEPALAGvrHKLvGGLRLPNDETGDCQLFTQRLAAMAEQLGVKFRFNTPVDGLLVEGGRIT 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 232 VtcqpsaehpylVESDNIQLEGDVLVVCGGVGSYQLADMIGERVNVYPVKGYSITVQLKDEHSvnnAPWVSLLDESAKIV 311
Cdd:PRK00711 236 G-----------VQTGGGVITADAYVVALGSYSTALLKPLGVDIPVYPLKGYSLTVPITDEDR---APVSTVLDETYKIA 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 312 TSRLGkDRLRVAGTAEFNGYNRDIRADRIQPLVNWVNRNF----DISteHVVPWAGLRPMMPNMLPVVKQSKQPRVFYNT 387
Cdd:PRK00711 302 ITRFD-DRIRVGGMAEIVGFDLRLDPARRETLEMVVRDLFpgggDLS--QATFWTGLRPMTPDGTPIVGATRYKNLWLNT 378

                        410       420
                 ....*....|....*....|....*..
gi 515955408 388 GHGHLGWTLSAATAVLVGQDIAQKYPA 414
Cdd:PRK00711 379 GHGTLGWTMACGSGQLLADLISGRKPA 405
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
1-409 1.20e-81

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 254.83  E-value: 1.20e-81
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRHlYPAMETSFANGGQLSACNAEVWNQkatvikgfkwmrqkdaplllnp 80
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERG-RPGSGASGRNAGQLRPGLAALADR---------------------- 58

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  81 sfslhkyswlveflshiknyeantiETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGT 160
Cdd:COG0665   59 -------------------------ALVRLAREALDLWRELAAELGIDCDFRRTGVLYLARTEAELAALRAEAEALRALG 113

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 161 LERYSVSPDEMKTIEPSL-TGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVtcqpsae 239
Cdd:COG0665  114 LPVELLDAAELREREPGLgSPDYAGGLYDPDDGHVDPAKLVRALARAARAAGVRIREGTPVTGLEREGGRVTG------- 186

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 240 hpylVESDNIQLEGDVLVVCGGVGSYQLADMIGERVNVYPVKGYSITVQLKDEhsvnnAPWVSLLDESaKIVTSRLGKDR 319
Cdd:COG0665  187 ----VRTERGTVRADAVVLAAGAWSARLLPMLGLRLPLRPVRGYVLVTEPLPD-----LPLRPVLDDT-GVYLRPTADGR 256

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 320 LRVAGTAEFNGYNRDIRADRIQPLVNWVNRNF----DISTEHVvpWAGLRPMMPNMLPVVKQS-KQPRVFYNTGHGHLGW 394
Cdd:COG0665  257 LLVGGTAEPAGFDRAPTPERLEALLRRLRRLFpalaDAEIVRA--WAGLRPMTPDGLPIIGRLpGAPGLYVATGHGGHGV 334

                        410
                 ....*....|....*
gi 515955408 395 TLSAATAVLVGQDIA 409
Cdd:COG0665  335 TLAPAAGRLLADLIL 349
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 3-406 2.38e-60

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 199.16  E-value: 2.38e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408    3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETSFANGGQLsacnaevwnqkatvikgfkwmrqkdaplllnpsf 82
Cdd:pfam01266   1 DVVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSGASGRNAGLI---------------------------------- 46

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   83 slhkYSWLveflshiknYEANTIETVRLALLARKRLFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGTLE 162
Cdd:pfam01266  47 ----HPGL---------RYLEPSELARLALEALDLWEELEEELGIDCGFRRCGVLVLARDEEEEALEKLLAALRRLGVPA 113

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  163 RYsVSPDEMKTIEPsLTGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVTCQPSAehpy 242
Cdd:pfam01266 114 EL-LDAEELRELEP-LLPGLRGGLFYPDGGHVDPARLLRALARAAEALGVRIIEGTEVTGIEEEGGVWGVVTTGEA---- 187

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  243 lvesdniqlegDVLVVCGGVGSyQLADMIGERVNVYPVKGYSITVQLKDEHSVNNAPWVSLLDESAKIVTSRLGkDRLRV 322
Cdd:pfam01266 188 -----------DAVVNAAGAWA-DLLALPGLRLPVRPVRGQVLVLEPLPEALLILPVPITVDPGRGVYLRPRAD-GRLLL 254

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  323 AGTAEFNGYNR-DIRADRIQPLVNWVNRNFDISTEHVVPWAGLRPMmPNMLPVVKQSKQPRVFYNTGHGHLGWTLSAATA 401
Cdd:pfam01266 255 GGTDEEDGFDDpTPDPEEIEELLEAARRLFPALADIERAWAGLRPL-PDGLPIIGRPGSPGLYLATGHGGHGLTLAPGIG 333


                  ....*
gi 515955408  402 VLVGQ 406
Cdd:pfam01266 334 KLLAE 338
thiamin_ThiO TIGR02352
glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine ...
 18-411 8.92e-26

glycine oxidase ThiO; This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine]


Pssm-ID: 274092 [Multi-domain]  Cd Length: 337  Bit Score: 106.68  E-value: 8.92e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   18 YELSQLGYQVTVIDRHLyPAMETSFANGGQLSAcNAEVWNQKATVIkgfkwmrqkdaplllnpsfslhkyswlveflshi 97
Cdd:TIGR02352   1 WELAKRGHSVTLFDRDP-MGGGASWAAAGMLAP-HAECEYAEDPLF---------------------------------- 44

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   98 knyeantietvRLALLARKR----LFEVAEKEQLEFDLEKRGILHMYHSKADYEIAKQVNNVLNKGTLERYSVSPDEMKT 173
Cdd:TIGR02352  45 -----------DLALESLRLypewLEALKELTGLDTGYHQCGTLVVAFDEDDVEHLRQLADLQSATGMEVEWLSGRALRR 113

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  174 IEPSLTGDYFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVvtcqpsaehpyLVESDNIQLEG 253
Cdd:TIGR02352 114 LEPYLSGGIRGAVFYPDDAHVDPRALLKALEKALEKLGVEIIEHTEVQHIEIRGEKVT-----------AIVTPSGDVQA 182

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  254 DVLVVCGGVGSYQLadmigERVNVYPVKGYSITVQLKDEHSVNNAPWVSLLDESAKIVTSRlgKDRLRVAGTAEFNGYNR 333
Cdd:TIGR02352 183 DQVVLAAGAWAGEL-----LPLPLRPVRGQPLRLEAPAVPLLNRPLRAVVYGRRVYIVPRR--DGRLVVGATMEESGFDT 255

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  334 DIRADRIQPLVNWVnrnfdistEHVVP----------WAGLRPMMPNMLPVV-KQSKQPRVFYNTGHGHLGWTLSAATAV 402
Cdd:TIGR02352 256 TPTLGGIKELLRDA--------YTILPalkearlletWAGLRPGTPDNLPYIgEHPEDRRLLIATGHYRNGILLAPATAE 327


                  ....*....
gi 515955408  403 LVGQDIAQK 411
Cdd:TIGR02352 328 VIADLILGK 336
LhgO COG0579
L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];
1-282 1.73e-18

L-2-hydroxyglutarate oxidase LhgO [Carbohydrate transport and metabolism];


Pssm-ID: 440344 [Multi-domain]  Cd Length: 418  Bit Score: 86.74  E-value: 1.73e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQL-GYQVTVIDRHLYPAMETSFANGGQLSAcnaevwnqkatvikGFkwmrqkdapllln 79
Cdd:COG0579    4 MYDVVIIGAGIVGLALARELSRYeDLKVLVLEKEDDVAQESSGNNSGVIHA--------------GL------------- 56

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408  80 psfslhkyswlveflshikNYEANTIEtVRLALLARKRLFEVAEkeQLEFDLEKRGilHMY--HSKAD-------YEIAK 150
Cdd:COG0579   57 -------------------YYTPGSLK-ARLCVEGNELFYELCR--ELGIPFKRCG--KLVvaTGEEEvafleklYERGK 112

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 151 QvNNVLNkgtLERysVSPDEMKTIEPSLTGDYFGGYYTPSdaTGDI--HKYSTSLAEKTKQYGVQYKFGLEVMDIKCSAD 228
Cdd:COG0579  113 A-NGVPG---LEI--LDREELRELEPLLSDEGVAALYSPS--TGIVdpGALTRALAENAEANGVELLLNTEVTGIEREGD 184

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 515955408 229 KVVVTcqpsaehpylveSDNIQLEGDVLVVCGGVGSYQLADMIGERVNV--YPVKG 282
Cdd:COG0579  185 GWEVT------------TNGGTIRARFVINAAGLYADRLAQMAGIGKDFgiFPVKG 228
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 3-41 1.44e-08

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 56.78  E-value: 1.44e-08
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETS 41
Cdd:PRK01747 262 DAAIIGGGIAGAALALALARRGWQVTLYEADEAPAQGAS 300
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 1-32 3.46e-08

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 55.22  E-value: 3.46e-08
                         10        20        30
                 ....*....|....*....|....*....|..
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:COG1232    1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEA 32
COG3380 COG3380
Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];
1-32 1.19e-07

Predicted NAD/FAD-dependent oxidoreductase [General function prediction only];


Pssm-ID: 442607 [Multi-domain]  Cd Length: 331  Bit Score: 52.96  E-value: 1.19e-07
                         10        20        30
                 ....*....|....*....|....*....|..
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:COG3380    3 MPDIAIIGAGIAGLAAARALQDAGHEVTVFEK 34
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
1-32 1.38e-07

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 53.39  E-value: 1.38e-07
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVI---DR 32
Cdd:COG1231    7 GKDVVIVGAGLAGLAAARELRKAGLDVTVLearDR 41
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 1-33 7.36e-07

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 50.71  E-value: 7.36e-07
                         10        20        30
                 ....*....|....*....|....*....|...
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:COG0654    3 RTDVLIVGGGPAGLALALALARAGIRVTVVERA 35
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
6-33 2.23e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 44.83  E-value: 2.23e-06
                          10        20
                  ....*....|....*....|....*...
gi 515955408    6 VIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKR 28
PRK11728 PRK11728
L-2-hydroxyglutarate oxidase;
161-277 2.92e-06

L-2-hydroxyglutarate oxidase;


Pssm-ID: 183292 [Multi-domain]  Cd Length: 393  Bit Score: 49.05  E-value: 2.92e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 161 LERYSVSPDEMKTIEPSLTGdyFGGYYTPSDATGDIHKYSTSLAEKTKQYGVQYKFGLEVMDIKCSADKVVVTCQPSaeh 240
Cdd:PRK11728 115 IEVERLDAEELREREPNIRG--LGAIFVPSTGIVDYRAVAEAMAELIQARGGEIRLGAEVTALDEHANGVVVRTTQG--- 189

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 515955408 241 pylvesdniQLEGDVLVVCGGVGSYQLADMIGERVNV 277
Cdd:PRK11728 190 ---------EYEARTLINCAGLMSDRLAKMAGLEPDF 217
PRK07208 PRK07208
hypothetical protein; Provisional
 1-32 7.82e-06

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 47.96  E-value: 7.82e-06
                         10        20        30
                 ....*....|....*....|....*....|..
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:PRK07208   4 KKSVVIIGAGPAGLTAAYELLKRGYPVTVLEA 35
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 1-36 8.74e-06

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 47.92  E-value: 8.74e-06
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYP 36
Cdd:COG1233    3 MYDVVVIGAGIGGLAAAALLARAGYRVTVLEKNDTP 38
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 1-32 1.22e-05

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 47.16  E-value: 1.22e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:COG3349    3 PPRVVVVGGGLAGLAAAVELAEAGFRVTLLEA 34
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
1-35 1.52e-05

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 46.66  E-value: 1.52e-05
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQL---GYQVTVIDRHLY 35
Cdd:COG1252    1 MKRIVIVGGGFAGLEAARRLRKKlggDAEVTLIDPNPY 38
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 3-33 2.35e-05

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 42.19  E-value: 2.35e-05
                          10        20        30
                  ....*....|....*....|....*....|.
gi 515955408    3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERR 31
PRK11883 PRK11883
protoporphyrinogen oxidase; Reviewed
 2-31 6.90e-05

protoporphyrinogen oxidase; Reviewed


Pssm-ID: 237009 [Multi-domain]  Cd Length: 451  Bit Score: 44.84  E-value: 6.90e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 515955408   2 PHVIVIGAGITGVTSAYELSQLG--YQVTVID 31
Cdd:PRK11883   1 KKVAIIGGGITGLSAAYRLHKKGpdADITLLE 32
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 1-33 1.23e-04

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 44.08  E-value: 1.23e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:COG2072    6 HVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKA 38
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 3-33 1.48e-04

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 43.63  E-value: 1.48e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:PRK11749 142 KVAVIGAGPAGLTAAHRLARKGYDVTIFEAR 172
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 3-35 1.81e-04

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 43.54  E-value: 1.81e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRHLY 35
Cdd:COG1249    5 DLVVIGAGPGGYVAAIRAAQLGLKVALVEKGRL 37
PRK07233 PRK07233
hypothetical protein; Provisional
 3-33 2.05e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 43.34  E-value: 2.05e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEAD 31
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 3-32 2.43e-04

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 42.75  E-value: 2.43e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:COG0569   97 HVIIIGAGRVGRSLARELEEEGHDVVVIDK 126
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
4-32 2.55e-04

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 43.31  E-value: 2.55e-04
                         10        20
                 ....*....|....*....|....*....
gi 515955408   4 VIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:COG1148  143 ALVIGGGIAGMTAALELAEQGYEVYLVEK 171
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 3-33 3.15e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 42.81  E-value: 3.15e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:COG0493  123 KVAVVGSGPAGLAAAYQLARAGHEVTVFEAL 153
COG3573 COG3573
Predicted oxidoreductase [General function prediction only];
4-47 3.21e-04

Predicted oxidoreductase [General function prediction only];


Pssm-ID: 442794 [Multi-domain]  Cd Length: 551  Bit Score: 42.86  E-value: 3.21e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 515955408   4 VIVIGAGITGVTSAYELSQLGYQVTVIDRhlypamETSFANGGQ 47
Cdd:COG3573    8 VIVVGAGLAGLVAAAELADAGRRVLLLDQ------EPEANLGGQ 45
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 3-33 7.50e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 41.78  E-value: 7.50e-04
                         10        20        30
                 ....*....|....*....|....*....|.
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:PRK12771 139 RVAVIGGGPAGLSAAYHLRRMGHAVTIFEAG 169
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 3-44 1.09e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 40.76  E-value: 1.09e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 515955408    3 HVIVIGAGITGVTSAYELSQLGYQVTVIDR--HLYPAMETSFAN 44
Cdd:pfam07992 154 RVVVVGGGYIGVELAAALAKLGKEVTLIEAldRLLRAFDEEISA 197
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 4-33 1.51e-03

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 40.39  E-value: 1.51e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 515955408    4 VIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:pfam01494   4 VLIVGGGPAGLMLALLLARAGVRVVLVERH 33
PRK05868 PRK05868
FAD-binding protein;
1-33 2.33e-03

FAD-binding protein;


Pssm-ID: 180297 [Multi-domain]  Cd Length: 372  Bit Score: 39.97  E-value: 2.33e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:PRK05868   1 MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERH 33
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 2-32 2.62e-03

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 39.61  E-value: 2.62e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 515955408    2 PHVIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:pfam07992   1 YDVVVIGGGPAGLAAALTLAQLGGKVTLIED 31
PRK06753 PRK06753
hypothetical protein; Provisional
 4-33 3.27e-03

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 39.29  E-value: 3.27e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 515955408   4 VIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:PRK06753   3 IAIIGAGIGGLTAAALLQEQGHEVKVFEKN 32
PRK12834 PRK12834
putative FAD-binding dehydrogenase; Reviewed
 4-31 3.44e-03

putative FAD-binding dehydrogenase; Reviewed


Pssm-ID: 183782 [Multi-domain]  Cd Length: 549  Bit Score: 39.50  E-value: 3.44e-03
                         10        20
                 ....*....|....*....|....*...
gi 515955408   4 VIVIGAGITGVTSAYELSQLGYQVTVID 31
Cdd:PRK12834   7 VIVVGAGLAGLVAAAELADAGKRVLLLD 34
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
203-288 3.47e-03

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 39.18  E-value: 3.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515955408 203 LAEKTKQYGVQYKFGLEVMDIKCSADKVVVTCqpsaehpylveSDNIQLEGDVLVVCGGVGSyQLADMIGERVNVYPVKG 282
Cdd:COG0644   92 LAEQAEEAGAEVRTGTRVTDVLRDDGRVVVRT-----------GDGEEIRADYVVDADGARS-LLARKLGLKRRSDEPQD 159


                 ....*.
gi 515955408 283 YSITVQ 288
Cdd:COG0644  160 YALAIK 165
PTZ00139 PTZ00139
Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Provisional
 5-74 4.54e-03

Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Provisional


Pssm-ID: 240286 [Multi-domain]  Cd Length: 617  Bit Score: 39.34  E-value: 4.54e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 515955408   5 IVIGAGITGVTSAYELSQLGYQVTVIDRhLYPAM-ETSFANGG---QLSACNAEVWNQKA-TVIKGFKWMRQKDA 74
Cdd:PTZ00139  33 VVVGAGGAGLRAALGLVELGYKTACISK-LFPTRsHTVAAQGGinaALGNMTEDDWRWHAyDTVKGSDWLGDQDA 106
Ppro0129 COG2907
Predicted flavin-containing amine oxidase [General function prediction only];
1-36 4.72e-03

Predicted flavin-containing amine oxidase [General function prediction only];


Pssm-ID: 442151 [Multi-domain]  Cd Length: 423  Bit Score: 38.94  E-value: 4.72e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 515955408   1 MPHVIVIGAGITGVTSAYELSQLgYQVTVIDRHLYP 36
Cdd:COG2907    3 RMRIAVIGSGISGLTAAWLLSRR-HDVTLFEANDRL 37
PLN02268 PLN02268
probable polyamine oxidase
 2-31 4.77e-03

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 38.90  E-value: 4.77e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 515955408   2 PHVIVIGAGITGVTSAYELSQLGYQVTVID 31
Cdd:PLN02268   1 PSVIVIGGGIAGIAAARALHDASFKVTLLE 30
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
4-33 5.19e-03

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 38.36  E-value: 5.19e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 515955408    4 VIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:pfam13738 158 VVVIGGYNSAVDAALELVRKGARVTVLYRG 187
PRK12814 PRK12814
putative NADPH-dependent glutamate synthase small subunit; Provisional
 3-33 5.34e-03

putative NADPH-dependent glutamate synthase small subunit; Provisional


Pssm-ID: 139246 [Multi-domain]  Cd Length: 652  Bit Score: 38.94  E-value: 5.34e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRH 33
Cdd:PRK12814 195 KVAIIGAGPAGLTAAYYLLRKGHDVTIFDAN 225
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 3-46 6.40e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 38.42  E-value: 6.40e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 515955408    3 HVIVIGAGITGVTSAYELSQLGYQVTVIDRHLYPAMETSFANGG 46
Cdd:pfam00890   1 DVLVIGGGLAGLAAALAAAEAGLKVAVVEKGQPFGGATAWSSGG 44
MurD COG0771
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ...
 3-32 8.36e-03

UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis


Pssm-ID: 440534 [Multi-domain]  Cd Length: 445  Bit Score: 38.14  E-value: 8.36e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 515955408   3 HVIVIGAGITGVTSAYELSQLGYQVTVIDR 32
Cdd:COG0771    6 KVLVLGLGKSGLAAARLLAKLGAEVTVSDD 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH