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Conserved domains on  [gi|515958905|ref|WP_017389488|]
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nucleoside triphosphate pyrophosphatase [Acinetobacter calcoaceticus]

Protein Classification

Maf family protein( domain architecture ID 10785471)

multicopy associated filamentation (Maf) family protein is involved in septum formation and also has a role as a house-cleaning NTP pyrophosphatase

CATH:  3.90.950.10
EC:  3.6.1.-
Gene Ontology:  GO:0009117|GO:0047429|GO:0009146|GO:0000166
PubMed:  24210219
SCOP:  4000520

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-197 1.45e-72

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440193  Cd Length: 189  Bit Score: 217.60  E-value: 1.45e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   4 PQIILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDF 83
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARLPDALVLGADTVVVLD---GRI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  84 IGKPMTIENAKVQLAENSGRTVYFSTALSVqWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:COG0424   78 LGKPADAEEARAMLRRLSGRTHRVHTGVAL-IDPGGRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGA 156

                        170       180       190
                 ....*....|....*....|....*....|....
gi 515958905 164 SLFEKMTGqDQTTLMGLPMIQLCHILRQLGLQIP 197
Cdd:COG0424  157 ALVERIEG-SYSNVVGLPLIELLELLRELGVDLL 189
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-197 1.45e-72

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 217.60  E-value: 1.45e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   4 PQIILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDF 83
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARLPDALVLGADTVVVLD---GRI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  84 IGKPMTIENAKVQLAENSGRTVYFSTALSVqWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:COG0424   78 LGKPADAEEARAMLRRLSGRTHRVHTGVAL-IDPGGRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGA 156

                        170       180       190
                 ....*....|....*....|....*....|....
gi 515958905 164 SLFEKMTGqDQTTLMGLPMIQLCHILRQLGLQIP 197
Cdd:COG0424  157 ALVERIEG-SYSNVVGLPLIELLELLRELGVDLL 189
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 6-189 2.08e-58

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 181.14  E-value: 2.08e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPH-AIIIGSDQVAWREhapNDFI 84
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPdALVIGADTVVVLD---GRIL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  85 GKPMTIENAKVQLAENSGRTVYFSTALSVqWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGIS 164
Cdd:cd00555   78 GKPKDREEAREMLKRLSGRTHEVYTGVAL-IDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGA 156

                        170       180
                 ....*....|....*....|....*
gi 515958905 165 LFEKMTGqDQTTLMGLPMIQLCHIL 189
Cdd:cd00555  157 LIERIEG-DYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 6-192 5.35e-58

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 179.91  E-value: 5.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905    6 IILASSSQTRKALMDRLGINYICVSPDIDESPRDE-IHADELAKRLAFTKAQviaaknphAIIIGSDQVAWREhapndfI 84
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKEdPAPEEYVLRLARAKAE--------ALVIGADTVVVLI------L 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   85 GKPMTIENAKVQLAENSGRTVYFSTALSV-QWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:pfam02545  67 GKPKDEEEARAMLKRLSGRTHEVYTGVALiNPGGGTGGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGA 146

                         170       180
                  ....*....|....*....|....*....
gi 515958905  164 SLFEKMTGqDQTTLMGLPMIQLCHILRQL 192
Cdd:pfam02545 147 ALVERIEG-DYSNVVGLPLIELLRLLREL 174
PRK02141 PRK02141
Maf-like protein; Reviewed
 4-194 4.75e-52

Maf-like protein; Reviewed


Pssm-ID: 235009  Cd Length: 207  Bit Score: 166.08  E-value: 4.75e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   4 PQIILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAK---NPHAIIIGSDQVAWREHAP 80
Cdd:PRK02141   9 PRLILASSSRYRRELLERLRLPFDVVSPDIDETPLAGETPAATALRLAAAKARAVAATidaPPGALVIGSDQVATFDGLQ 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  81 ndfIGKPMTIENAKVQLAENSGRTVYFSTALSVqwLDRNFEQTLVEHYQ--VKFRTLNQAEIERYIALEQPLHCAGSFKC 158
Cdd:PRK02141  89 ---IGKPGTHERALAQLQAMRGRTVEFHSALCL--YDSRTGETQSEDVVtrVRFRTLTDAELDAYLRAETPYDVAGSAKS 163

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 515958905 159 ESLGISLFEKMTGQDQTTLMGLPMIQLCHILRQLGL 194
Cdd:PRK02141 164 EGLGIALLDAIDSDDPTALVGLPLIALTRMLRAAGY 199
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 4-190 2.70e-44

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 145.62  E-value: 2.70e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905    4 PQIILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDF 83
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELLADALIIGADTVVILD---GEI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   84 IGKPMTIENAKVQLAENSGRTVYFSTALSVQwlDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:TIGR00172  80 YGKPKDKEEAAEFLRKLSGQEHEVYTAVALI--DSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGA 157

                         170       180
                  ....*....|....*....|....*..
gi 515958905  164 SLFEKMTGqDQTTLMGLPMIQLCHILR 190
Cdd:TIGR00172 158 PLIKKIDG-DYSNVVGLPLEKLLGALR 183
 
Name Accession Description Interval E-value
Maf COG0424
7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary ...
 4-197 1.45e-72

7-methyl-GTP pyrophosphatase and related NTP pyrophosphatases, Maf/HAM1 superfamily [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440193  Cd Length: 189  Bit Score: 217.60  E-value: 1.45e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   4 PQIILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDF 83
Cdd:COG0424    1 PKLILASASPRRRELLEQLGLPFEVVPPDIDETPLPGESPEELVLRLARAKAEAVAARLPDALVLGADTVVVLD---GRI 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  84 IGKPMTIENAKVQLAENSGRTVYFSTALSVqWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:COG0424   78 LGKPADAEEARAMLRRLSGRTHRVHTGVAL-IDPGGRLWTRVVTTRVTFRPLSDAEIEAYLATGEPLDKAGAYGIQGLGA 156

                        170       180       190
                 ....*....|....*....|....*....|....
gi 515958905 164 SLFEKMTGqDQTTLMGLPMIQLCHILRQLGLQIP 197
Cdd:COG0424  157 ALVERIEG-SYSNVVGLPLIELLELLRELGVDLL 189
Maf cd00555
Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in ...
 6-189 2.08e-58

Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.


Pssm-ID: 238310  Cd Length: 180  Bit Score: 181.14  E-value: 2.08e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPH-AIIIGSDQVAWREhapNDFI 84
Cdd:cd00555    1 LILASASPRRRELLEQLGIPFEVVPSDIDETPIKGESPEDYVLRLAEAKAEAVAARLPPdALVIGADTVVVLD---GRIL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  85 GKPMTIENAKVQLAENSGRTVYFSTALSVqWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGIS 164
Cdd:cd00555   78 GKPKDREEAREMLKRLSGRTHEVYTGVAL-IDPGGKLVTDVESTKVRFRELSDEEIEAYVASGEPLDKAGAYGIQGLGGA 156

                        170       180
                 ....*....|....*....|....*
gi 515958905 165 LFEKMTGqDQTTLMGLPMIQLCHIL 189
Cdd:cd00555  157 LIERIEG-DYSNVVGLPLPELLKLL 180
Maf pfam02545
Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and ...
 6-192 5.35e-58

Maf-like protein; Maf is a putative inhibitor of septum formation in eukaryotes, bacteria, and archaea.


Pssm-ID: 460586  Cd Length: 174  Bit Score: 179.91  E-value: 5.35e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905    6 IILASSSQTRKALMDRLGINYICVSPDIDESPRDE-IHADELAKRLAFTKAQviaaknphAIIIGSDQVAWREhapndfI 84
Cdd:pfam02545   1 LILASASPRRRELLEQLGIEFEVVPSDIDETPLKEdPAPEEYVLRLARAKAE--------ALVIGADTVVVLI------L 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   85 GKPMTIENAKVQLAENSGRTVYFSTALSV-QWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:pfam02545  67 GKPKDEEEARAMLKRLSGRTHEVYTGVALiNPGGGTGGVSFVETTRVTFRPLSDEEIEAYVATGEPLDKAGAYGIQGLGA 146

                         170       180
                  ....*....|....*....|....*....
gi 515958905  164 SLFEKMTGqDQTTLMGLPMIQLCHILRQL 192
Cdd:pfam02545 147 ALVERIEG-DYSNVVGLPLIELLRLLREL 174
PRK02141 PRK02141
Maf-like protein; Reviewed
 4-194 4.75e-52

Maf-like protein; Reviewed


Pssm-ID: 235009  Cd Length: 207  Bit Score: 166.08  E-value: 4.75e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   4 PQIILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAK---NPHAIIIGSDQVAWREHAP 80
Cdd:PRK02141   9 PRLILASSSRYRRELLERLRLPFDVVSPDIDETPLAGETPAATALRLAAAKARAVAATidaPPGALVIGSDQVATFDGLQ 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  81 ndfIGKPMTIENAKVQLAENSGRTVYFSTALSVqwLDRNFEQTLVEHYQ--VKFRTLNQAEIERYIALEQPLHCAGSFKC 158
Cdd:PRK02141  89 ---IGKPGTHERALAQLQAMRGRTVEFHSALCL--YDSRTGETQSEDVVtrVRFRTLTDAELDAYLRAETPYDVAGSAKS 163

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 515958905 159 ESLGISLFEKMTGQDQTTLMGLPMIQLCHILRQLGL 194
Cdd:PRK02141 164 EGLGIALLDAIDSDDPTALVGLPLIALTRMLRAAGY 199
maf TIGR00172
MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A ...
 4-190 2.70e-44

MAF protein; This nonessential gene causes inhibition of septation when overexpressed. A member of the family is found in the Archaeon Pyrococcus horikoshii and another in the round worm Caenorhabditis elegans. [Cellular processes, Cell division]


Pssm-ID: 129276  Cd Length: 183  Bit Score: 145.62  E-value: 2.70e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905    4 PQIILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDF 83
Cdd:TIGR00172   3 KELILASQSPRRKELLEELGISFEQIVSEFDEKSLKTTSPRELVYRLAKEKAQAVAELLADALIIGADTVVILD---GEI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   84 IGKPMTIENAKVQLAENSGRTVYFSTALSVQwlDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:TIGR00172  80 YGKPKDKEEAAEFLRKLSGQEHEVYTAVALI--DSVHLLTFLDVTKVHFRALDPEEIEKYVESGEPLEKAGAFGIEGFGA 157

                         170       180
                  ....*....|....*....|....*..
gi 515958905  164 SLFEKMTGqDQTTLMGLPMIQLCHILR 190
Cdd:TIGR00172 158 PLIKKIDG-DYSNVVGLPLEKLLGALR 183
PRK14365 PRK14365
Maf-like protein; Provisional
 5-196 9.01e-29

Maf-like protein; Provisional


Pssm-ID: 237690  Cd Length: 197  Bit Score: 106.06  E-value: 9.01e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   5 QIILASSSQTRKALMDRL-GINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDF 83
Cdd:PRK14365   3 RIILASASPRRKELLKQLiGDNFLVYPSSYEEPPQPGLDPEELLLKHSLEKARDVAKHFDSGIIISADTSVFCN---GEV 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  84 IGKPMTIENAKVQLAENSGRTVYFSTALSVQWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:PRK14365  80 LGKPASPENAEEMLEKLSGRKFLVITGLTVLDLDSGKEISEIESTDVWMTELSREQILAYVRTGEPLDKAGAFAIQGKGA 159

                        170       180       190
                 ....*....|....*....|....*....|...
gi 515958905 164 SLFEKMTGqDQTTLMGLPMIQLCHILRQLGLQI 196
Cdd:PRK14365 160 VLVEKIEG-DFFNVVGLPLFRLGKILEKLGVSV 191
PRK00648 PRK00648
Maf-like protein; Reviewed
 4-193 1.23e-27

Maf-like protein; Reviewed


Pssm-ID: 234807  Cd Length: 191  Bit Score: 103.06  E-value: 1.23e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   4 PQIILASSSQTRKALMDRLGINYICV-SPDIDESPRDEIHADELAKRLAFTKAQVIAA-KNPHAIIIGSDQVAWREhapN 81
Cdd:PRK00648   3 YKIILASSSPRRKEILEGFRIPFEVVpSPFVEESYPYSLDPEEITLELARLKAEAVRSdLFPDELIITADTIVWYD---G 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  82 DFIGKPMTIENAKVQLAENSGRTVYFSTalSVQWLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFK-CES 160
Cdd:PRK00648  80 KVLGKPKDEEEAVEMLRTLSGKTHEVIT--GVCLLHNGKLLSGSETTQVTFRELSDEEIEYYIDTYKPLDKAGAYGiQEW 157

                        170       180       190
                 ....*....|....*....|....*....|...
gi 515958905 161 LGIsLFEKMTGqDQTTLMGLPMIQLCHILRQLG 193
Cdd:PRK00648 158 GGL-IVKKIEG-SYYNVMGLPIQTLYEELKELG 188
PRK02478 PRK02478
Maf-like protein; Reviewed
 4-193 2.46e-27

Maf-like protein; Reviewed


Pssm-ID: 167380  Cd Length: 199  Bit Score: 102.51  E-value: 2.46e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   4 PQIILASSSQTRKALMDRLGINYICVSPDIDE----SPRDEIHA--DELAKRLAFTKAQVIAAKNPHAIIIGSDQVAwre 77
Cdd:PRK02478   3 VKLILASKSPFRRALLENAGLEFSAAAADIDEraveAPLEESGAtpEDVALVLAEAKAIDVSERFPGALVIGCDQTM--- 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  78 hAPNDFI-GKPMTIENAKVQLAENSGRTVYFSTALSvqwLDRNFEQ--TLVEHYQVKFRTLNQAEIERYIAL--EQPLHC 152
Cdd:PRK02478  80 -SLGDEVfHKPKDMEEARRHLQKLSGKTHQLNSAVV---LVRDGKVlwRHVSIAHMTMRDLDAGFIGRHLARvgEKALSS 155

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 515958905 153 AGSFKCESLGISLFEKMTGqDQTTLMGLPMIQLCHILRQLG 193
Cdd:PRK02478 156 VGAYQLEGEGIQLFEKIEG-DYFTILGLPLLPLLAKLRELG 195
PRK14363 PRK14363
Maf-like protein; Provisional
 5-182 3.88e-22

Maf-like protein; Provisional


Pssm-ID: 184647  Cd Length: 204  Bit Score: 88.80  E-value: 3.88e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   5 QIILASSSQTRKALMDRLGINYICVSPDIDESPRDEihADELAKRLAFTKAQVIAAKNP--HAIIIGSDQVAWREhapND 82
Cdd:PRK14363   2 RIILASSSPRRRQLMELLGIEFEVEKPDVEEEFLES--PEETVRELSLRKAEWVFKKRKeeEILVIGSDTVVVLD---GN 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  83 FIGKPMTIENAKVQLAENSGRTVYFSTALSVqwLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLG 162
Cdd:PRK14363  77 ILGKPESLEEAKGMLKKLSGRWHVVYTGVAF--VSSETKDVIVSSTKVRFRELPESVIDYYVEKYRPLDKAGAYGIQDFA 154

                        170       180
                 ....*....|....*....|
gi 515958905 163 ISLFEKMTGqDQTTLMGLPM 182
Cdd:PRK14363 155 AVFVEKIEG-DFFTVVGFPL 173
PRK14361 PRK14361
Maf-like protein; Provisional
 6-196 5.93e-22

Maf-like protein; Provisional


Pssm-ID: 172837  Cd Length: 187  Bit Score: 88.06  E-value: 5.93e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLGINY-ICVSPDIDESPrdEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDFI 84
Cdd:PRK14361   1 VILASGSPRRRELLENLGVPFqVVVSGEAEDST--ETDPARLAAELALLKARAVARLHPDAVVIAADTVVALG---GVLL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  85 GKPM-TIENAKVqLAENSGRTVYFSTALSVqwLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:PRK14361  76 AKPAdEAENEAF-LRVLSGRTHQVYTGVAV--LSRGTEQVGVERTDVTFRALTAAEISFYARSGEGLDKAGGYGIQGVGM 152

                        170       180       190
                 ....*....|....*....|....*....|...
gi 515958905 164 SLFEKMTGqDQTTLMGLPMIQLCHILRQLGLQI 196
Cdd:PRK14361 153 ALVSRVEG-DYSNVVGFPLSLVIRLLRGAGVPV 184
Maf_Ham1 cd00985
Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum ...
 6-132 1.00e-20

Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides, such as hypoxanthine/xanthine NTP, but not standard nucleotides.


Pssm-ID: 238485  Cd Length: 131  Bit Score: 83.32  E-value: 1.00e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLG-INYICVSPDIDESPrDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREHAPndfI 84
Cdd:cd00985    1 LILASGSPRRLEELKQIGgIEFEVLPSDIDETG-LKGEPEDTVEELALLKARAVAERLPDAPVIADDTGLVVDGRP---G 76

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 515958905  85 GKPMTIENAKVQLAENSGRTVYFSTALSVQWLDRNfEQTLVEHYQVKF 132
Cdd:cd00985   77 GKPARFAEALEMLRGLSGRTAEFVTAVALVDPDGK-IITFEGETEGKI 123
PRK14364 PRK14364
Maf-like protein; Provisional
 8-192 8.10e-20

Maf-like protein; Provisional


Pssm-ID: 184648  Cd Length: 181  Bit Score: 82.36  E-value: 8.10e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   8 LASSSQTRKALMDRLGINYICVSPDIDESprdeIHADEL----AKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDF 83
Cdd:PRK14364   1 LASSSPRRRELLQQLGLNFEIYSPDIDES----VHEGELvhqyVERLAREKAQAVLNIFPDSVIIAADTSLGLD---GQI 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  84 IGKPMTIENAKVQLAENSGR--TVYFSTALSVQwldrNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESL 161
Cdd:PRK14364  74 IGKPDSKQHAFDIWKQLSGRwhDVFSGICIATQ----QQILSQVVQTQVEFASLTTQDMEDYWATGEPVGKAGAYAIQGI 149

                        170       180       190
                 ....*....|....*....|....*....|.
gi 515958905 162 GISLFEKMTGQdQTTLMGLPMIQLCHILRQL 192
Cdd:PRK14364 150 ASQYIPKIQGS-YSNVVGLPLYEFSQLFKRV 179
PRK04694 PRK04694
Maf-like protein; Reviewed
 8-193 1.28e-19

Maf-like protein; Reviewed


Pssm-ID: 179873  Cd Length: 190  Bit Score: 81.93  E-value: 1.28e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   8 LASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQV----IAAKNPHAIIIGSD-QVAWREHApnd 82
Cdd:PRK04694   4 LASRSPRRRELLQRLDVPFQTLQLDVPEVRAADESPDHYVQRVALEKAHAglalVQAADADAIVLGSDtEVVLGERV--- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  83 fIGKPMTIENAKVQLAENSGRTVYFSTALSVQWLDRNFEQTLVEHyQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLG 162
Cdd:PRK04694  81 -FGKPVDVDDAIAMLRALSGRTHQVLTAVVLVCAQRAPAQALVVS-EVTFDLLDDAQIAAYAASGEPMGKAGAYAIQGRA 158

                        170       180       190
                 ....*....|....*....|....*....|.
gi 515958905 163 ISLFEKMTGQdQTTLMGLPMIQLCHILRQLG 193
Cdd:PRK04694 159 ERFIRHLSGS-YSGVMGLPLYQTSQLLTAFG 188
PRK14368 PRK14368
Maf-like protein; Provisional
 6-193 1.65e-19

Maf-like protein; Provisional


Pssm-ID: 237693  Cd Length: 193  Bit Score: 81.75  E-value: 1.65e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDFIG 85
Cdd:PRK14368   7 IVLASASPRRSELLASAGIEFDVVPADIPEEPLPGEEPVDHVLRLAREKARAAAALAEGRFFIGADTIVVCD---GEIMG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  86 KPMTIENAKVQLAENSGRTVYFSTALSVqwLDRNFEQTLVE--HYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGI 163
Cdd:PRK14368  84 KPKDEADAVRMLKKLSGVPHEVITGFAV--YDRERDGCVTKavRTKVFFKPLRDEEIRDYIATGCPMDKAGAYAIQGGAA 161

                        170       180       190
                 ....*....|....*....|....*....|
gi 515958905 164 SLFEKMTGQdQTTLMGLPMIQLCHILRQLG 193
Cdd:PRK14368 162 HMVRKIDGS-YTNVVGLPLCEVVEALRTIG 190
PRK00078 PRK00078
Maf-like protein; Reviewed
 5-196 1.98e-18

Maf-like protein; Reviewed


Pssm-ID: 234618  Cd Length: 192  Bit Score: 79.00  E-value: 1.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   5 QIILASSSQTRKALMDRLGINYICVSPDIDESPRD-EIHADELAKRLAFTKAQVIAAK--NPHAIIIGSDQVAWREhapN 81
Cdd:PRK00078   2 KIILASASERRQELLKRILEDFQVIVSDFDESSVPfKGNIESYVMNLAEGKARSVSKKldQESSIVIGCDTIVAFN---G 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  82 DFIGKPMTIENAKVQLAENSGRT--VYFSTALsvqwLDRNFEQTLVEHY--QVKFRTLNQAEIERYIALEQPLHCAGSFK 157
Cdd:PRK00078  79 KVLGKPKDEEDAFEMLKALSGNEheVYSGIAI----LDTKSNKIIKDFVctEVKFSKLTDRQIRKYINTGEPMDKAGAYG 154

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 515958905 158 CESLGISLFEKMTGqDQTTLMGLPMIQLCHILRQLGLQI 196
Cdd:PRK00078 155 IQGKGGVFVEEING-CYYNVVGLPLNKLYKMLEEMGVNL 192
PRK01441 PRK01441
Maf-like protein; Reviewed
 2-182 2.43e-15

Maf-like protein; Reviewed


Pssm-ID: 167232  Cd Length: 207  Bit Score: 70.90  E-value: 2.43e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   2 VQPQIILASSSQTRKALMDRLGINYICVSP-DIDESPRDEIHADELAKRLAFTKAQviAAKNP--------HAIIIGSDQ 72
Cdd:PRK01441   3 GRPKLVLASGSPRRVELLNQAGIEPDRLMPaDIDETPKRAEHPRSLARRLSREKAE--AALEAlqgdddwrGAYILAADT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  73 VAwreHAPNDFIGKPMTIENAKVQLAENSGRTVYFSTALSVQWLDRNFEQTLVEhYQVKFRTLNQAEIERYIALEQPLHC 152
Cdd:PRK01441  81 VV---AVGRRILPKAELVDEASQCLRLLSGRNHRVYTGVCLVTPDGKLRQKLVE-TRVRFKRLSREDIEAYLASGEWRGK 156

                        170       180       190
                 ....*....|....*....|....*....|
gi 515958905 153 AGSFKCESLGISLFEKMTGQdQTTLMGLPM 182
Cdd:PRK01441 157 AGGYAIQGIAGSFVVKLVGS-YTNVVGLPL 185
PRK14362 PRK14362
Maf-like protein; Provisional
 6-197 1.84e-14

Maf-like protein; Provisional


Pssm-ID: 172838  Cd Length: 207  Bit Score: 68.73  E-value: 1.84e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLGINYICVSP-DIDESPRDEIHADELAKRLAFTKAQVIAAKNPHAIIIGSDQVAWREhapNDFI 84
Cdd:PRK14362  14 VVLASGSPRRREFLEQMGLPFEVILPgAAEPSPIEGEQPEAYARRAAEAKARAVAADHAGRLVIAADTVVALD---GMIL 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  85 GKPMTIENAKVQLAENSGRTVYFSTALSVQwLDRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKCESLGIS 164
Cdd:PRK14362  91 GKPADRADALSMLRRLAGRTHEVVSACCVV-LPDGGREVFHAITRVTMWDWPEAALAAYVATGEPSDKAGAYGIQGIGAF 169

                        170       180       190
                 ....*....|....*....|....*....|...
gi 515958905 165 LFEKMTGQdQTTLMGLPMIQLCHILRQLGLQIP 197
Cdd:PRK14362 170 LVRSIEGS-WSNVVGLPVAELTALLLRRGVILP 201
PRK14366 PRK14366
Maf-like protein; Provisional
 6-191 1.01e-13

Maf-like protein; Provisional


Pssm-ID: 237691  Cd Length: 195  Bit Score: 66.36  E-value: 1.01e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLGINY-ICVSPDIDESPrdeiHADELAK----RLAFTKAQVIAAKNPHAIIIGSDQVAW--REH 78
Cdd:PRK14366   7 LILASSSKQRLALLEQIGVVPgEIVSPDIDESP----LKKELPKdysiRMAKEKAEKVQSLRPDKFVLGADTVVCcgRRI 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  79 APndfigKPMTIENAKVQLAENSGR--TVYFSTALSVQWLDRNfEQTLVEhyQVKFRTLNQAEIERYIALEQPLHCAGSF 156
Cdd:PRK14366  83 LL-----KAETEEQAEEYLELLSGRrhRVYTSVCLYTPGGKLH-IRSVVT--VVKFKRLSKQEIKYYIASGEWKGKAGGC 154

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 515958905 157 KCESLGISLFEKMTGQdQTTLMGLPMIQLCHILRQ 191
Cdd:PRK14366 155 NIQGLAGKFVLSINGS-YSSIIGLPLHETYCLLSG 188
PRK14367 PRK14367
Maf-like protein; Provisional
 6-197 7.88e-09

Maf-like protein; Provisional


Pssm-ID: 237692  Cd Length: 202  Bit Score: 53.15  E-value: 7.88e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   6 IILASSSQTRKALMDRLGINYICVSPDIDESPRDEIHADELAKRLAFTKAQV-------IAAKNPHAIIIGSDQVAWREH 78
Cdd:PRK14367   4 LYLGSNSPRRMEILTQLGYRVVKLPAGIDETVKAGETPARYVQRMAEEKNRTaltlfceTNGTMPDFPLITADTCVVSDG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  79 ApndFIGKPMTIENAKVQLAENSGRTVYFSTALSVQWldRNFEQTLVEHYQVKFRTLNQAEIERYIALEQPLHCAGSFKC 158
Cdd:PRK14367  84 I---ILGKPRSQAEAIEFLNRLSGKQHTVLTAVCIHY--RGKTSSRVQTNRVVFKPLSSEEISAYVQSGEPMDKAGAYAV 158

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 515958905 159 ESLGISLFEKMTGQdQTTLMGLPMIQLCHILRQLGLQIP 197
Cdd:PRK14367 159 QGIGGIFIQSIEGS-FSGIMGLPVYETVSMLQDLGYRSP 196
PRK04056 PRK04056
septum formation inhibitor Maf;
5-180 2.00e-04

septum formation inhibitor Maf;


Pssm-ID: 179732  Cd Length: 180  Bit Score: 40.33  E-value: 2.00e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905   5 QIILASSSQTRKALMDRLGINYICVSPDIDES------PRDEIHADELAKRLAFTKAQVIaaknpHAIIIGSDQVAwreH 78
Cdd:PRK04056   1 MIILASSSSTRANLLKEAGIEFEQKSLDFDEEsikktsPKEFVYLAVKGKLEQFLKKYGN-----ECNLLVADSVV---S 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515958905  79 APNDFIGKPMTIENAKVQLAENSGRTVYFSTALSVQWLDRNFEQTLVEHYqvKFRTLNQAEIERYIALEQPLHCAGSFKC 158
Cdd:PRK04056  73 CGNKILRKAKDKEEAREMLKLQSGNEISVLTCMILKSPEKEWLDLSVTTY--RFKKFDEDDLEKYLESGLWQGKAGACMV 150

                        170       180
                 ....*....|....*....|..
gi 515958905 159 ESLGISLFEKMTGQDQTTlMGL 180
Cdd:PRK04056 151 EGFHKKYIKSVSGNESTA-MGL 171
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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