|
Name |
Accession |
Description |
Interval |
E-value |
| mpl |
TIGR01081 |
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: ... |
2-453 |
0e+00 |
|
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: murein tripeptide ligase [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 130153 [Multi-domain] Cd Length: 448 Bit Score: 588.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 2 HLHILGICGTFMGSLALLARDLGHKVTGSDLNVYPPMSTQLENAGITLMQGYDRSHLQPHPDLVIVGNAMKRGIDAVEYM 81
Cdd:TIGR01081 1 HIHILGICGTFMGGLAMIAKQLGHEVTGSDANVYPPMSTQLEAQGIEIIEGFDAAQLEPKPDLVVIGNAMKRGNPCVEAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 82 LNEGLPYISGPQFLADHVLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPLGFSESARLGGGKYFCVEADE 161
Cdd:TIGR01081 81 LNLNLPYTSGPQWLHDFVLHDRWVLAVAGTHGKTTTASMLAWVLEQCGLKPGFLIGGVPGNFGVSARLGESPFFVIEADE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 162 YDSAFFDKRSKFVHYHPKTAILNNLEFDHADIFDDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEMGCWTPVIRT 241
Cdd:TIGR01081 161 YDTAFFDKRSKFVHYRPRTLVLNNLEFDHADIFDDLKAIQRQFHHLVRTVPGEGLILCPGRDQSLKDTLAKGCWSEQEFF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 242 SleanEKAALSAELISIDGSHFKVLENGNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRRMEL 321
Cdd:TIGR01081 241 G----EQGEWQAEKITADGSHFDVLLDGEKVGEVKWSLVGRHNMHNALMAIAAARHVGVAIEDACEALGSFVNAKRRLEL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 322 LGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPRSNTMRMGSHKDGLAHSARLADEVIWYQPEGLDWDLQP 401
Cdd:TIGR01081 317 KGEANGITVYDDFAHHPTAIEATLQGLRQKVGGARILAVLEPRSNTMKLGVHKDDLAPSLGRADQVFLYQPGQIPWDVAE 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 515969082 402 VIEAASNHAQVSRSLDNIIQRIVNEAGEGDAVVIMSNGGFGGLHQKLMSALK 453
Cdd:TIGR01081 397 VAAQCVQPANVSADFDAFVAMIVKNAQPGDHILVMSNGGFGGIHGKLLDALR 448
|
|
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-448 |
0e+00 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 521.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 1 MHLHILGICGTFMGSLALLARDLGHKVTGSDLNVYPpMSTQLENAGITLMQGYDRSHLqPHPDLVIVGNAMKRGIDAVEY 80
Cdd:COG0773 5 MHIHFIGIGGIGMSGLAEILLALGYKVSGSDLAESP-MTERLEALGIPVFIGHDAENI-DDADLVVVSSAIPRDNPELVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 81 MLNEGLPYISGPQFLADHvLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPLGFSESARLGGGKYFCVEAD 160
Cdd:COG0773 83 ARERGIPVLSRAEMLAEL-MRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDGDYFVAEAD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 161 EYDSAFfdkrskfVHYHPKTAILNNLEFDHADIFDDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEMgCWTPVIR 240
Cdd:COG0773 162 ESDGSF-------LHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPR-CGRPVIT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 241 TSLeaNEKAALSAELISI--DGSHFKVLENGNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRR 318
Cdd:COG0773 234 YGF--SEDADYRAENIRIdgGGSTFDVLRRGEELGEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 319 MELLGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPRSNTmRMGSHKDGLAHSARLADEVIWYQPEGL--- 395
Cdd:COG0773 312 FELKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYS-RTRDFLDEFAEALSLADEVILLDIYAArek 390
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 515969082 396 ---DWDLQPV---IEAASNHAQVSRSLDNIIQRIVNEAGEGDAVVIMSNGGFGGLHQKL 448
Cdd:COG0773 391 pipGVSSEDLaeaIRKRGKDVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGLGEKL 449
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
1-388 |
9.03e-37 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 143.80 E-value: 9.03e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 1 MHLHILGICGTFMGSLALLARDLGHKVTGSDLNvYPPMSTQLENAGITLMQGYDRSHLqPHPDLVIVGNAMKRgiDAVEY 80
Cdd:PRK14573 5 LFYHFIGIGGIGMSALAHILLDRGYSVSGSDLS-EGKTVEKLKAKGARFFLGHQEEHV-PEDAVVVYSSSISK--DNVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 81 M--LNEGLPYISGPQFLADhVLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPlGFSESARLGGGKYFCVE 158
Cdd:PRK14573 81 LsaKSRGNRLVHRAELLAE-LMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGGLN-QEGLNGYSGSSEYFVAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 159 ADEYDSAffdkrskFVHYHPKTAILNNLEFDHADIF----DDLAAIQKQFHHLVRTIPSegriiapitethidevlemgC 234
Cdd:PRK14573 159 ADESDGS-------LKHYTPEFSVITNIDNEHLSNFegdrELLLASIQDFARKVQQINK--------------------C 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 235 W----TPVIRTSLEA-----NEKAALSAELISIDG--SHFKVLENGNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLE 303
Cdd:PRK14573 212 FyngdCPRLKGCLQGhsygfSSSCDLHILSYYQEGwrSYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEG 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 304 QACEALSNFGGVKRRMELLGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPRSNTmRMGSHKDGLAHSARL 383
Cdd:PRK14573 292 AIRNALKGFSGVQRRLERKNSSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFS-RLRECLDSFPSAFQD 370
|
....*
gi 515969082 384 ADEVI 388
Cdd:PRK14573 371 ADEVI 375
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
2-101 |
1.07e-13 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 66.10 E-value: 1.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 2 HLHILGICGTFMGSLALLARDLGHKVTGSDLNVYppmstqLENAGITLMQGYDRshlqphpdlvivGNAMKRGIDAVEYM 81
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFIES------LIALGAAAVVGHDA------------ANNISPDNPELEAA 62
|
90 100
....*....|....*....|
gi 515969082 82 LNEGLPYISGPQFLADHVLQ 101
Cdd:pfam01225 63 KVPGIPVIDRREALAELAAA 82
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| mpl |
TIGR01081 |
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: ... |
2-453 |
0e+00 |
|
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase; Alternate name: murein tripeptide ligase [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 130153 [Multi-domain] Cd Length: 448 Bit Score: 588.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 2 HLHILGICGTFMGSLALLARDLGHKVTGSDLNVYPPMSTQLENAGITLMQGYDRSHLQPHPDLVIVGNAMKRGIDAVEYM 81
Cdd:TIGR01081 1 HIHILGICGTFMGGLAMIAKQLGHEVTGSDANVYPPMSTQLEAQGIEIIEGFDAAQLEPKPDLVVIGNAMKRGNPCVEAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 82 LNEGLPYISGPQFLADHVLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPLGFSESARLGGGKYFCVEADE 161
Cdd:TIGR01081 81 LNLNLPYTSGPQWLHDFVLHDRWVLAVAGTHGKTTTASMLAWVLEQCGLKPGFLIGGVPGNFGVSARLGESPFFVIEADE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 162 YDSAFFDKRSKFVHYHPKTAILNNLEFDHADIFDDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEMGCWTPVIRT 241
Cdd:TIGR01081 161 YDTAFFDKRSKFVHYRPRTLVLNNLEFDHADIFDDLKAIQRQFHHLVRTVPGEGLILCPGRDQSLKDTLAKGCWSEQEFF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 242 SleanEKAALSAELISIDGSHFKVLENGNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRRMEL 321
Cdd:TIGR01081 241 G----EQGEWQAEKITADGSHFDVLLDGEKVGEVKWSLVGRHNMHNALMAIAAARHVGVAIEDACEALGSFVNAKRRLEL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 322 LGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPRSNTMRMGSHKDGLAHSARLADEVIWYQPEGLDWDLQP 401
Cdd:TIGR01081 317 KGEANGITVYDDFAHHPTAIEATLQGLRQKVGGARILAVLEPRSNTMKLGVHKDDLAPSLGRADQVFLYQPGQIPWDVAE 396
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 515969082 402 VIEAASNHAQVSRSLDNIIQRIVNEAGEGDAVVIMSNGGFGGLHQKLMSALK 453
Cdd:TIGR01081 397 VAAQCVQPANVSADFDAFVAMIVKNAQPGDHILVMSNGGFGGIHGKLLDALR 448
|
|
| MurC |
COG0773 |
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall ... |
1-448 |
0e+00 |
|
UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramate-alanine ligase MurC and related ligases, MurC/Mpl family is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440536 [Multi-domain] Cd Length: 451 Bit Score: 521.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 1 MHLHILGICGTFMGSLALLARDLGHKVTGSDLNVYPpMSTQLENAGITLMQGYDRSHLqPHPDLVIVGNAMKRGIDAVEY 80
Cdd:COG0773 5 MHIHFIGIGGIGMSGLAEILLALGYKVSGSDLAESP-MTERLEALGIPVFIGHDAENI-DDADLVVVSSAIPRDNPELVA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 81 MLNEGLPYISGPQFLADHvLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPLGFSESARLGGGKYFCVEAD 160
Cdd:COG0773 83 ARERGIPVLSRAEMLAEL-MRGKRSIAVAGTHGKTTTTSMLAHILEEAGLDPTFLIGGILNNFGTNARLGDGDYFVAEAD 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 161 EYDSAFfdkrskfVHYHPKTAILNNLEFDHADIFDDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEMgCWTPVIR 240
Cdd:COG0773 162 ESDGSF-------LHYSPDIAVVTNIEADHLDIYGDLEAIKEAFHEFARNVPFYGLLVLCADDPGLRELLPR-CGRPVIT 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 241 TSLeaNEKAALSAELISI--DGSHFKVLENGNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRR 318
Cdd:COG0773 234 YGF--SEDADYRAENIRIdgGGSTFDVLRRGEELGEVELNLPGRHNVLNALAAIAVALELGVDPEAIAEALASFKGVKRR 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 319 MELLGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPRSNTmRMGSHKDGLAHSARLADEVIWYQPEGL--- 395
Cdd:COG0773 312 FELKGEVGGVTVIDDYAHHPTEIAATLAAAREKYPDRRLVAVFQPHRYS-RTRDFLDEFAEALSLADEVILLDIYAArek 390
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 515969082 396 ---DWDLQPV---IEAASNHAQVSRSLDNIIQRIVNEAGEGDAVVIMSNGGFGGLHQKL 448
Cdd:COG0773 391 pipGVSSEDLaeaIRKRGKDVVYVPDLDELVEALAEIARPGDVVLTMGAGDIGGLGEKL 449
|
|
| murC |
TIGR01082 |
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial ... |
2-388 |
1.62e-72 |
|
UDP-N-acetylmuramate--L-alanine ligase; This model describes the MurC protein in bacterial peptidoglycan (murein) biosynthesis. In a few species (Mycobacterium leprae, the Chlamydia), the amino acid may be L-serine or glycine instead of L-alanine. A related protein, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase (murein tripeptide ligase) is described by model TIGR01081. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273433 [Multi-domain] Cd Length: 448 Bit Score: 235.28 E-value: 1.62e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 2 HLHILGICGTFMGSLALLARDLGHKVTGSDLNVYPpMSTQLENAGITLMQGYDRSHLQpHPDLVIVGNAMKRGIDAVEYM 81
Cdd:TIGR01082 1 KIHFVGIGGIGMSGIAEILLNRGYQVSGSDIAENA-TTKRLEALGIPIYIGHSAENLD-DADVVVVSAAIKDDNPEIVEA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 82 LNEGLPYISGPQFLADhVLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPLGFSESARLGGGKYFCVEADE 161
Cdd:TIGR01082 79 KERGIPVIRRAEMLAE-LMRFRHSIAVAGTHGKTTTTAMIAVILKEAGLDPTVVVGGLVKEAGTNARLGSGEYLVAEADE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 162 YDSAFfdkrskfVHYHPKTAILNNLEFDHADIF-DDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEMGcwTPVIR 240
Cdd:TIGR01082 158 SDASF-------LHLQPNVAIVTNIEPDHLDTYgSSFERLKAAFEKFIHNLPFYGLAVICADDPVLRELVPKA--TEQVI 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 241 TSLEANEKAALSAELISIDG--SHFKVLENGNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRR 318
Cdd:TIGR01082 229 TYGGSGEDADYRAENIQQSGaeGKFSVRGKGKLYLEFTLNLPGRHNVLNALAAIAVALELGIDFEAILRALANFQGVKRR 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 515969082 319 MELLGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPR--SNTMRMgshKDGLAHSARLADEVI 388
Cdd:TIGR01082 309 FEILGEFGGVLLIDDYAHHPTEIKATLKAARQGYPDKRIVVVFQPHrySRTRDL---FDDFAKVLSDADELI 377
|
|
| PRK14573 |
PRK14573 |
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase; |
1-388 |
9.03e-37 |
|
bifunctional UDP-N-acetylmuramate--L-alanine ligase/D-alanine--D-alanine ligase;
Pssm-ID: 184752 [Multi-domain] Cd Length: 809 Bit Score: 143.80 E-value: 9.03e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 1 MHLHILGICGTFMGSLALLARDLGHKVTGSDLNvYPPMSTQLENAGITLMQGYDRSHLqPHPDLVIVGNAMKRgiDAVEY 80
Cdd:PRK14573 5 LFYHFIGIGGIGMSALAHILLDRGYSVSGSDLS-EGKTVEKLKAKGARFFLGHQEEHV-PEDAVVVYSSSISK--DNVEY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 81 M--LNEGLPYISGPQFLADhVLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFLIGGVPlGFSESARLGGGKYFCVE 158
Cdd:PRK14573 81 LsaKSRGNRLVHRAELLAE-LMQEQISILVSGSHGKTTVSSLITAIFQEAKKDPSYAIGGLN-QEGLNGYSGSSEYFVAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 159 ADEYDSAffdkrskFVHYHPKTAILNNLEFDHADIF----DDLAAIQKQFHHLVRTIPSegriiapitethidevlemgC 234
Cdd:PRK14573 159 ADESDGS-------LKHYTPEFSVITNIDNEHLSNFegdrELLLASIQDFARKVQQINK--------------------C 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 235 W----TPVIRTSLEA-----NEKAALSAELISIDG--SHFKVLENGNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLE 303
Cdd:PRK14573 212 FyngdCPRLKGCLQGhsygfSSSCDLHILSYYQEGwrSYFSAKFLGVVYQDIELNLVGMHNVANAAAAMGIALTLGIDEG 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 304 QACEALSNFGGVKRRMELLGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLWAIIEPRSNTmRMGSHKDGLAHSARL 383
Cdd:PRK14573 292 AIRNALKGFSGVQRRLERKNSSETFLFLEDYAHHPSEISCTLRAVRDAVGLRRIIAICQPHRFS-RLRECLDSFPSAFQD 370
|
....*
gi 515969082 384 ADEVI 388
Cdd:PRK14573 371 ADEVI 375
|
|
| Mur_ligase |
pfam01225 |
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes ... |
2-101 |
1.07e-13 |
|
Mur ligase family, catalytic domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460121 [Multi-domain] Cd Length: 84 Bit Score: 66.10 E-value: 1.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 2 HLHILGICGTFMGSLALLARDLGHKVTGSDLNVYppmstqLENAGITLMQGYDRshlqphpdlvivGNAMKRGIDAVEYM 81
Cdd:pfam01225 1 EIHFVGIDGRGMSPGALFLALKGYRVDGSDFIES------LIALGAAAVVGHDA------------ANNISPDNPELEAA 62
|
90 100
....*....|....*....|
gi 515969082 82 LNEGLPYISGPQFLADHVLQ 101
Cdd:pfam01225 63 KVPGIPVIDRREALAELAAA 82
|
|
| MurE |
COG0769 |
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
104-388 |
2.24e-11 |
|
UDP-N-acetylmuramyl tripeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl tripeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440532 [Multi-domain] Cd Length: 459 Bit Score: 65.49 E-value: 2.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 104 HVLGVAGTHGKTTTTTMLAWVLDQAGLNPGfLIG--GVPLG-------------------FSESARlGGGKYFCVEA--- 159
Cdd:COG0769 81 KLIGVTGTNGKTTTTYLLAQILRALGKKTG-LIGtvGNGIGgelipsslttpealdlqrlLAEMVD-AGVTHVVMEVssh 158
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 160 --DEYdsaffdkRSKFVHYHpkTAILNNLEFDHADifddlaaiqkqFHH-----------LVRTIPSEGRIIAPITETHI 226
Cdd:COG0769 159 alDQG-------RVDGVRFD--VAVFTNLTRDHLD-----------YHGtmeayfaakarLFDQLGPGGAAVINADDPYG 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 227 DEVLEMgCWTPVIRTSLEANekAALSAELI--SIDGSHFKVLENGNVVgEVKWSMTGQHSVANALATIAAAQHVGVTLEQ 304
Cdd:COG0769 219 RRLAAA-APARVITYGLKAD--ADLRATDIelSADGTRFTLVTPGGEV-EVRLPLIGRFNVYNALAAIAAALALGIDLEE 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 305 ACEALSNFGGVKRRMELLGTVNGIEVYDDFAHHPTAIDTTLDGARKrLGERRLWAII---EPRSNTMR--MGshkdglAH 379
Cdd:COG0769 295 ILAALEKLKGVPGRMERVDGGQGPTVIVDYAHTPDALENVLEALRP-HTKGRLIVVFgcgGDRDRGKRplMG------EI 367
|
....*....
gi 515969082 380 SARLADEVI 388
Cdd:COG0769 368 AARLADVVI 376
|
|
| murE |
TIGR01085 |
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, ... |
84-439 |
1.23e-10 |
|
UDP-N-acetylmuramyl-tripeptide synthetase; Most members of this family are EC 6.3.2.13, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase. An exception is Staphylococcus aureus, in which diaminopimelate is replaced by lysine in the peptidoglycan and MurE is EC 6.3.2.7. The Mycobacteria, part of the closest neighboring branch outside of the low-GC Gram-positive bacteria, use diaminopimelate. A close homolog, scoring just below the trusted cutoff, is found (with introns) in Arabidopsis thaliana. Its role is unknown. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273435 [Multi-domain] Cd Length: 464 Bit Score: 63.10 E-value: 1.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 84 EGLPYISGPQF----------LADHVLQGKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPGFL-----------IGGVPLG 142
Cdd:TIGR01085 56 APVPVIIVPDLrhalsslaaaFYGHPSKKLKVIGVTGTNGKTTTTSLIAQLLRLLGKKTGLIgtigyrlggndLIKNPAA 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 143 FS-----------ESARLGGGKYFCVEADEYdsAFFDKRSKFVHYhpKTAILNNLEFDHADI---FDDLAAIQKqfhHLV 208
Cdd:TIGR01085 136 LTtpealtlqstlAEMVEAGAQYAVMEVSSH--ALAQGRVRGVRF--DAAVFTNLSRDHLDFhgtMENYFAAKA---SLF 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 209 RTIPSEGRIIAPITETHIDEVLEMgcwTPVIRTSLEANEKAALSAELISI-------DGSHFKVLENGNvVGEVKWSMTG 281
Cdd:TIGR01085 209 TELGLKRFAVINLDDEYGAQFVKR---LPKDITVSAITQPADGRAQDIKItdsgysfEGQQFTFETPAG-EGHLHTPLIG 284
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 282 QHSVANALATIAAAQHVG-VTLEQACEALSNFGGVKRRMELLGTVNGIEVYDDFAHHPTAIDTTLDGARKrLGERRLWAI 360
Cdd:TIGR01085 285 RFNVYNLLAALATLLHLGgIDLEDIVAALEKFRGVPGRMELVDGGQKFLVIVDYAHTPDALEKALRTLRK-HKDGRLIVV 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 361 I---EPRSNTMR--MGshkdglAHSARLADEVIWYQ-------PE--------GLDWDLQPVIEAASNHAqvsrsldniI 420
Cdd:TIGR01085 364 FgcgGDRDRGKRplMG------AIAEQLADLVILTSdnprgedPEqiiadilaGISEKEKVVIIADRRQA---------I 428
|
410
....*....|....*....
gi 515969082 421 QRIVNEAGEGDAVVIMSNG 439
Cdd:TIGR01085 429 RYAISNAKAGDVVLIAGKG 447
|
|
| Mur_ligase_C |
pfam02875 |
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase ... |
315-358 |
1.26e-09 |
|
Mur ligase family, glutamate ligase domain; This family contains a number of related ligase enzymes which have EC numbers 6.3.2.*. This family includes: MurC, MurD, MurE, MurF, Mpl and FolC. MurC, MurD, Mure and MurF catalyze consecutive steps in the synthesis of peptidoglycan. Peptidoglycan consists of a sheet of two sugar derivatives, with one of these N-acetylmuramic acid attaching to a small pentapeptide. The pentapeptide is is made of L-alanine, D-glutamic acid, Meso-diaminopimelic acid and D-alanyl alanine. The peptide moiety is synthesized by successively adding these amino acids to UDP-N-acetylmuramic acid. MurC transfers the L-alanine, MurD transfers the D-glutamate, MurE transfers the diaminopimelic acid, and MurF transfers the D-alanyl alanine. This family also includes Folylpolyglutamate synthase that transfers glutamate to folylpolyglutamate.
Pssm-ID: 460731 [Multi-domain] Cd Length: 87 Bit Score: 54.66 E-value: 1.26e-09
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 515969082 315 VKRRMELLGTVNGIEVYDDFAHHPTAIDTTLDGARKRLGERRLW 358
Cdd:pfam02875 1 VPGRLEVVGENNGVLVIDDYAHNPDAMEAALRALRNLFPGRLIL 44
|
|
| murD |
TIGR01087 |
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation ... |
6-333 |
2.00e-09 |
|
UDP-N-acetylmuramoylalanine--D-glutamate ligase; [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273436 [Multi-domain] Cd Length: 433 Bit Score: 59.28 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 6 LGICGtfmGSLALLARDLGHKVTGSDL--NVYPPMSTQLENAGITLMQGYDRSHLQPH-PDLVIVGNAMKRGIDAVEYML 82
Cdd:TIGR01087 7 LGKTG---RAVARFLHKKGAEVTVTDLkpNEELEPSMGQLRLNEGSVLHTGLHLEDLNnADLVVKSPGIPPDHPLVQAAA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 83 NEGLPYISGPQFLADHVlqGKHVLGVAGTHGKTTTTTMLAWVLDQAGLnPGFLIG--GVPlgFSESARLGGGKYFCVEAd 160
Cdd:TIGR01087 84 KRGIPVVGDIELFLRLV--PLPVVAITGTNGKTTTTSLLYHLLKAAGL-KAFLGGniGTP--ALEVLDQEGAELYVLEL- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 161 eydSAFFDKRSKFVHyhPKTAILNNLEFDHADIFDDL----AAIQKQFHHLvrtiPSEGRIIAPItethIDEVLEMGCWT 236
Cdd:TIGR01087 158 ---SSFQLETTESLR--PEIALILNISEDHLDWHGSFedyvAAKLKIFARQ----TEGDVAVLNA----DDPRFARLAQK 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 237 PVIRTSLEANEKAALSAELISIDGSHFKVlengnvvGEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVK 316
Cdd:TIGR01087 225 SKAQVIWFSVEKDAERGLCIRDGGLYLKP-------NDLEGSLLGLHNAENILAAIALAKSLGLNLEAILEALRSFKGLP 297
|
330
....*....|....*..
gi 515969082 317 RRMELLGTVNGIEVYDD 333
Cdd:TIGR01087 298 HRLEYVGQKNGVHFYND 314
|
|
| murE |
PRK00139 |
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional |
247-388 |
7.95e-08 |
|
UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional
Pssm-ID: 234660 [Multi-domain] Cd Length: 460 Bit Score: 54.37 E-value: 7.95e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 247 EKAALSAELISID--GSHFkvlengNVVGEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRRMELLGT 324
Cdd:PRK00139 246 AGADLRATDVEYTdsGQTF------TLVTEVESPLIGRFNVSNLLAALAALLALGVPLEDALAALAKLQGVPGRMERVDA 319
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 515969082 325 VNGIEVYDDFAHHPTAIDTTLDGARkRLGERRLWAII---EPRSNTMR--MGshkdglAHSARLADEVI 388
Cdd:PRK00139 320 GQGPLVIVDYAHTPDALEKVLEALR-PHAKGRLICVFgcgGDRDKGKRplMG------AIAERLADVVI 381
|
|
| Mur_ligase_M |
pfam08245 |
Mur ligase middle domain; |
108-285 |
1.15e-06 |
|
Mur ligase middle domain;
Pssm-ID: 462409 [Multi-domain] Cd Length: 199 Bit Score: 48.84 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 108 VAGTHGKTTTTTMLAWVLDQAGLN---PGFLIG----------GVPLGFSEsARLGGGKYFCVEADEYDSAffDKRSKFV 174
Cdd:pfam08245 1 VTGTNGKTTTTELIAAILSLAGGVigtIGTYIGksgnttnnaiGLPLTLAE-MVEAGAEYAVLEVSSHGLG--EGRLSGL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 175 hYHPKTAILNNLEFDHADIFDDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEM--GCWTPVIRTSLeaNEKAALS 252
Cdd:pfam08245 78 -LKPDIAVFTNISPDHLDFHGTMENYAKAKAELFEGLPEDGIAVINADDPYGAFLIAKlkKAGVRVITYGI--EGEADLR 154
|
170 180 190
....*....|....*....|....*....|....*
gi 515969082 253 AELISI--DGSHFKVLENGNVVGEVKWSMTGQHSV 285
Cdd:pfam08245 155 AANIELssDGTSFDLFTVPGGELEIEIPLLGRHNV 189
|
|
| MurF |
COG0770 |
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; ... |
178-333 |
2.41e-06 |
|
UDP-N-acetylmuramyl pentapeptide synthase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramyl pentapeptide synthase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440533 [Multi-domain] Cd Length: 451 Bit Score: 49.72 E-value: 2.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 178 PKTAILNNLEFDHADIFDDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEmGCWTPVIRTSLEANekAALSAELIS 257
Cdd:COG0770 176 PDIAVITNIGPAHLEGFGSLEGIARAKGEIFEGLPPGGVAVLNADDPLLAALAE-RAKARVLTFGLSED--ADVRAEDIE 252
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 515969082 258 ID--GSHFKVLENGNVVgEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRRMELLGTVNGIEVYDD 333
Cdd:COG0770 253 LDedGTRFTLHTPGGEL-EVTLPLPGRHNVSNALAAAAVALALGLDLEEIAAGLAAFQPVKGRLEVIEGAGGVTLIDD 329
|
|
| MurD |
COG0771 |
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; ... |
15-333 |
1.95e-05 |
|
UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell wall/membrane/envelope biogenesis]; UDP-N-acetylmuramoylalanine-D-glutamate ligase is part of the Pathway/BioSystem: Mureine biosynthesis
Pssm-ID: 440534 [Multi-domain] Cd Length: 445 Bit Score: 46.61 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 15 SLALLARDLGHKVTGSDLNVYPPMS-TQLENAGITLMQGYDRSHLQPHPDLVIV--G---------NAMKRGIdaveyml 82
Cdd:COG0771 18 AAARLLAKLGAEVTVSDDRPAPELAaAELEAPGVEVVLGEHPEELLDGADLVVKspGippdhpllkAARAAGI------- 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 83 neglPYISGPQFLAdHVLQGKhVLGVAGTHGKTTTTTMLAWVLDQAGLNPgFLIG--GVPlgFSESARlgggkyfcvEAD 160
Cdd:COG0771 91 ----PVIGEIELAY-RLSPAP-IIAITGTNGKTTTTTLIGHILKAAGLRV-AVGGniGTP--LLDLLL---------EPE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 161 EYD------SAF-------FdkrskfvhyHPKTAILNNLEFDHADIFDDLAA-IQ-KQfhHLVRTIPSEGRIIA----PI 221
Cdd:COG0771 153 PPDvyvlelSSFqlettpsL---------RPDVAVILNITPDHLDRHGSMEAyAAaKA--RIFANQTPDDYAVLnaddPL 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 222 TETHIDEVLemgcwTPVIRTSLEANEKAALSAE--LISIDGSHFKVLEngnvVGEVKwsMTGQHSVanalatiaaaQ--- 296
Cdd:COG0771 222 TRALAEEAK-----ARVVPFSLKEPLEGGAGLEdgKLVDRASGEELLP----VDDLR--LPGRHNL----------Enal 280
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 515969082 297 -------HVGVTLEQACEALSNFGGVKRRMELLGTVNGIEVYDD 333
Cdd:COG0771 281 aalaaarALGVPPEAIREALRSFKGLPHRLEFVAEINGVRFIND 324
|
|
| PRK11929 |
PRK11929 |
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE ... |
180-439 |
1.88e-04 |
|
bifunctional UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase MurE/UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF;
Pssm-ID: 237025 [Multi-domain] Cd Length: 958 Bit Score: 43.92 E-value: 1.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 180 TAILNNLEFDHADIFDDLAAIQKQFHHLVRTIPSEGRIIAPITETHIDEVLEMGCWTPVIRTSLEANEKAALSAELIsiD 259
Cdd:PRK11929 204 VAGFTNLTRDHLDYHGTMQDYEEAKAALFSKLPGLGAAVINADDPAAARLLAALPRGLKVGYSPQNAGADVQARDLR--A 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 260 GSHFKVLE----NGNVvgEVKWSMTGQHSVANALATIAAAQHVGVTLEQACEALSNFGGVKRRMELLGTV---NGIEVYD 332
Cdd:PRK11929 282 TAHGQVFTlatpDGSY--QLVTRLLGRFNVSNLLLVAAALKKLGLPLAQIARALAAVSPVPGRMERVGPTagaQGPLVVV 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 333 DFAHHPTAIDTTLDGAR--KRLGERRLWAII--------EPRSntmRMGshkdglAHSARLADEVIWYQPEGLDWDLQPV 402
Cdd:PRK11929 360 DYAHTPDALAKALTALRpvAQARNGRLVCVFgcggdrdkGKRP---EMG------RIAAELADRVVVTSDNPRSEAPEAI 430
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 515969082 403 IEA------ASNHAQVSRSLDNIIQRIVNEAGEGDAVVIMSNG 439
Cdd:PRK11929 431 IDQilagipAGARVFVISDRAEAIRQAIWMAAPGDVILIAGKG 473
|
|
| murD |
PRK14106 |
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional |
23-333 |
2.21e-03 |
|
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional
Pssm-ID: 184511 [Multi-domain] Cd Length: 450 Bit Score: 40.34 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 23 LGHKVTGSDLNVYPPMSTQLENA---GITLMQG-YDRSHLQPHpDLVIVGNAMKRGIDAVEYMLNEGLPYIsGPQFLADH 98
Cdd:PRK14106 27 LGAKVILTDEKEEDQLKEALEELgelGIELVLGeYPEEFLEGV-DLVVVSPGVPLDSPPVVQAHKKGIEVI-GEVELAYR 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 99 VLQgKHVLGVAGTHGKTTTTTMLAWVLDQAGLNPgfLIG---GVPLgFSESARLGGGKYFCVEAdeydSAFfdKRSKFVH 175
Cdd:PRK14106 105 FSK-APIVAITGTNGKTTTTTLLGEIFKNAGRKT--LVAgniGYPL-IDAVEEYGEDDIIVAEV----SSF--QLETIKE 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 176 YHPKTAILNNLEFDHAD--------------IF-------------DDLAAiqkqfHHLVRTIPseGRIIaPITETHIde 228
Cdd:PRK14106 175 FKPKVGCILNITPDHLDrhktmenyikakarIFenqrpsdytvlnyDDPRT-----RSLAKKAK--ARVI-FFSRKSL-- 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969082 229 vLEMGCWTP--VIRTSLEANEKAALSAELISIDGSHfkVLENGNVVGEVKWSMtgqhsvanalatiaaaqhvGVTLEQAC 306
Cdd:PRK14106 245 -LEEGVFVKngKIVISLGGKEEEVIDIDEIFIPGEH--NLENALAATAAAYLL-------------------GISPDVIA 302
|
330 340
....*....|....*....|....*..
gi 515969082 307 EALSNFGGVKRRMELLGTVNGIEVYDD 333
Cdd:PRK14106 303 NTLKTFKGVEHRIEFVAEINGVKFIND 329
|
|
| |
