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Conserved domains on  [gi|515969315|ref|WP_017399898|]
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MULTISPECIES: hypothetical protein [Acinetobacter]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 193-291 8.33e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.34  E-value: 8.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG2956  128 KAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDcaRALLLLAELYLEQGDYEEAIAALERALEQ 207

                         90       100
                 ....*....|....*....|.
gi 515969315 271 YPDEAEIADRLIQEIEKQGRW 291
Cdd:COG2956  208 DPDYLPALPRLAELYEKLGDP 228
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 193-291 8.33e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.34  E-value: 8.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG2956  128 KAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDcaRALLLLAELYLEQGDYEEAIAALERALEQ 207

                         90       100
                 ....*....|....*....|.
gi 515969315 271 YPDEAEIADRLIQEIEKQGRW 291
Cdd:COG2956  208 DPDYLPALPRLAELYEKLGDP 228
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 193-291 8.33e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 49.34  E-value: 8.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG2956  128 KAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDcaRALLLLAELYLEQGDYEEAIAALERALEQ 207

                         90       100
                 ....*....|....*....|.
gi 515969315 271 YPDEAEIADRLIQEIEKQGRW 291
Cdd:COG2956  208 DPDYLPALPRLAELYEKLGDP 228
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 193-285 3.99e-06

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.98  E-value: 3.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDD---AETNFWFGFGLSEGGGQREAIPYLDKAIKGN-----VQEAYLAAANNYIAMEQKKNAIQTL 264
Cdd:COG1729   11 EAIAAFKAFLKRYPNSplaPDALYWLGEAYYALGDYDEAAEAFEKLLKRYpdspkAPDALLKLGLSYLELGDYDKARATL 90

                         90       100
                 ....*....|....*....|...
gi 515969315 265 KNYKVKYPD--EAEIADRLIQEI 285
Cdd:COG1729   91 EELIKKYPDseAAKEARARLARL 113
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 193-291 9.89e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.41  E-value: 9.89e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIK--GNVQEAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG4783   22 EAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEldPDEPEARLNLGLALLKAGDYDEALALLEKALKL 101

                         90       100
                 ....*....|....*....|.
gi 515969315 271 YPDEAEIADRLIQEIEKQGRW 291
Cdd:COG4783  102 DPEHPEAYLRLARAYRALGRP 122
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 195-274 2.39e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.26  E-value: 2.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 195 LEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVKYP 272
Cdd:COG4783   58 IVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEhpEAYLRLARAYRALGRPDEAIAALEKALELDP 137


                 ..
gi 515969315 273 DE 274
Cdd:COG4783  138 DD 139
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
193-291 2.53e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 45.00  E-value: 2.53e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG0457   26 EAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDdaEALNNLGLALQALGRYEEALEDYDKALEL 105

                         90       100
                 ....*....|....*....|.
gi 515969315 271 YPDEAEIADRLIQEIEKQGRW 291
Cdd:COG0457  106 DPDDAEALYNLGLALLELGRY 126
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 195-299 2.61e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.75  E-value: 2.61e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 195 LEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIK--GNVQEAYLAAANNYIAMEQKKNAIQTLKNYKVKYP 272
Cdd:COG3914  132 LAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEldPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDP 211

                         90       100
                 ....*....|....*....|....*..
gi 515969315 273 DEAEIADRLIQEIEKQGRWNVWQVLTN 299
Cdd:COG3914  212 DNADAHSNLLFALRQACDWEVYDRFEE 238
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
193-290 4.81e-05

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 43.84  E-value: 4.81e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGN--VQEAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG0457   94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDpdDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                         90       100
                 ....*....|....*....|
gi 515969315 271 YPDEAEIADRLIQEIEKQGR 290
Cdd:COG0457  174 ALAALLAAALGEAALALAAA 193
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 193-292 2.22e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.02  E-value: 2.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG2956   26 KAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDraEALLELAQDYLKAGLLDRAEELLEKLLEL 105

                         90       100
                 ....*....|....*....|..
gi 515969315 271 YPDEAEIADRLIQEIEKQGRWN 292
Cdd:COG2956  106 DPDDAEALRLLAEIYEQEGDWE 127
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
193-273 4.91e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 4.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYlDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG3063   10 EAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNnaEALLNLAELLLELGDYDEALAYLERALEL 88


                 ...
gi 515969315 271 YPD 273
Cdd:COG3063   89 DPS 91
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 194-291 9.92e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 40.75  E-value: 9.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 194 SLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVKY 271
Cdd:COG3914   97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDfaEAYLNLGEALRRLGRLEEAIAALRRALELD 176

                         90       100
                 ....*....|....*....|
gi 515969315 272 PDEAEIADRLIQEIEKQGRW 291
Cdd:COG3914  177 PDNAEALNNLGNALQDLGRL 196
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 193-278 1.47e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.06  E-value: 1.47e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIK--GNVQEAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG4235   35 EALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAldPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114


                 ....*...
gi 515969315 271 YPDEAEIA 278
Cdd:COG4235  115 LPADAPAR 122
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 193-291 5.37e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 37.79  E-value: 5.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 515969315 193 KSLEYAQRLLKINPDDAETNFWFGFGLSEGGGQREAIPYLDKAIKGNVQ--EAYLAAANNYIAMEQKKNAIQTLKNYKVK 270
Cdd:COG2956  162 EAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDylPALPRLAELYEKLGDPEEALELLRKALEL 241

                         90       100
                 ....*....|....*....|.
gi 515969315 271 YPDEAEIaDRLIQEIEKQGRW 291
Cdd:COG2956  242 DPSDDLL-LALADLLERKEGL 261
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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