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Conserved domains on  [gi|516375653|ref|WP_017765686|]
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MULTISPECIES: ion channel [Aeromonas]

Protein Classification

YjbI and Ion_trans_2 domain-containing protein( domain architecture ID 11443141)

YjbI and Ion_trans_2 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 235-320 4.97e-12

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


:

Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 60.74  E-value: 4.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  235 ICSLFYFFFGLSFngnhlvYRPGAPFEQNaifLLECLYYSVVTFTTLGYGDFTPVG-LSRIFAAFEAFTGSFTLALFVVV 313
Cdd:pfam07885   1 IVLLLVLIFGTVY------YLLEEGWEWS---FLDALYFSFVTLTTVGYGDIVPLTdAGRLFTIFYILIGIPLFAIFLAV 71


                  ....*..
gi 516375653  314 FVKKMTR 320
Cdd:pfam07885  72 LGRFLTE 78
YjbI COG1357
Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];
57-137 6.01e-11

Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];


:

Pssm-ID: 440968 [Multi-domain]  Cd Length: 178  Bit Score: 60.34  E-value: 6.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  57 LARANLAGLNLVKkgaphgflLEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRWHNTRLDNL 136
Cdd:COG1357   76 LTGADLSGANLAN--------LSGANLSGANLSGANLRGANLSGANLSGADLSGADLSGANLSGADLSGANLSGANLSGA 147


                 .
gi 516375653 137 D 137
Cdd:COG1357  148 D 148
 
Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 235-320 4.97e-12

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 60.74  E-value: 4.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  235 ICSLFYFFFGLSFngnhlvYRPGAPFEQNaifLLECLYYSVVTFTTLGYGDFTPVG-LSRIFAAFEAFTGSFTLALFVVV 313
Cdd:pfam07885   1 IVLLLVLIFGTVY------YLLEEGWEWS---FLDALYFSFVTLTTVGYGDIVPLTdAGRLFTIFYILIGIPLFAIFLAV 71


                  ....*..
gi 516375653  314 FVKKMTR 320
Cdd:pfam07885  72 LGRFLTE 78
YjbI COG1357
Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];
57-137 6.01e-11

Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];


Pssm-ID: 440968 [Multi-domain]  Cd Length: 178  Bit Score: 60.34  E-value: 6.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  57 LARANLAGLNLVKkgaphgflLEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRWHNTRLDNL 136
Cdd:COG1357   76 LTGADLSGANLAN--------LSGANLSGANLSGANLRGANLSGANLSGADLSGADLSGANLSGADLSGANLSGANLSGA 147


                 .
gi 516375653 137 D 137
Cdd:COG1357  148 D 148
Pentapeptide pfam00805
Pentapeptide repeats (8 copies); These repeats are found in many cyanobacterial proteins. The ...
 81-123 3.13e-05

Pentapeptide repeats (8 copies); These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK. The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix. The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid.


Pssm-ID: 459943 [Multi-domain]  Cd Length: 40  Bit Score: 40.40  E-value: 3.13e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 516375653   81 CNLYRANLQGAHLYGLRMKGgslmkADLSDANLHCATLDDVNL 123
Cdd:pfam00805   1 ANLSGANLSGANLSGANLSG-----ANLTGANLSGADLSGANL 38
PRK15196 PRK15196
type III secretion system effector PipB2;
54-137 7.47e-04

type III secretion system effector PipB2;


Pssm-ID: 185118 [Multi-domain]  Cd Length: 350  Bit Score: 40.76  E-value: 7.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  54 GLQLARANLAGLNLvKKGAPHGFLLEQCNLY-----RANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRW 128
Cdd:PRK15196 221 GATLDHANLTGANL-QHASLLGCSMIECNCSganmdHTNLSGATLIRADMSGATLQGATIMAAIMEGAVLTRANLRKASF 299


                 ....*....
gi 516375653 129 HNTRLDNLD 137
Cdd:PRK15196 300 ISTNLDGAD 308
 
Name Accession Description Interval E-value
Ion_trans_2 pfam07885
Ion channel; This family includes the two membrane helix type ion channels found in bacteria.
 235-320 4.97e-12

Ion channel; This family includes the two membrane helix type ion channels found in bacteria.


Pssm-ID: 462301 [Multi-domain]  Cd Length: 78  Bit Score: 60.74  E-value: 4.97e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  235 ICSLFYFFFGLSFngnhlvYRPGAPFEQNaifLLECLYYSVVTFTTLGYGDFTPVG-LSRIFAAFEAFTGSFTLALFVVV 313
Cdd:pfam07885   1 IVLLLVLIFGTVY------YLLEEGWEWS---FLDALYFSFVTLTTVGYGDIVPLTdAGRLFTIFYILIGIPLFAIFLAV 71


                  ....*..
gi 516375653  314 FVKKMTR 320
Cdd:pfam07885  72 LGRFLTE 78
YjbI COG1357
Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];
57-137 6.01e-11

Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];


Pssm-ID: 440968 [Multi-domain]  Cd Length: 178  Bit Score: 60.34  E-value: 6.01e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  57 LARANLAGLNLVKkgaphgflLEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRWHNTRLDNL 136
Cdd:COG1357   76 LTGADLSGANLAN--------LSGANLSGANLSGANLRGANLSGANLSGADLSGADLSGANLSGADLSGANLSGANLSGA 147


                 .
gi 516375653 137 D 137
Cdd:COG1357  148 D 148
YjbI COG1357
Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];
54-137 4.02e-10

Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];


Pssm-ID: 440968 [Multi-domain]  Cd Length: 178  Bit Score: 58.03  E-value: 4.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  54 GLQLARANLAGLNLvkKGAphgflLEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRWHNTRL 133
Cdd:COG1357   14 GADLSGADLSGANL--SGA-----LSGANLSGANLSGANLTGANLSGADLSGADLSGANLSGADLSGANLTGADLSGANL 86


                 ....
gi 516375653 134 DNLD 137
Cdd:COG1357   87 ANLS 90
YjbI COG1357
Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];
57-137 1.03e-08

Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];


Pssm-ID: 440968 [Multi-domain]  Cd Length: 178  Bit Score: 53.79  E-value: 1.03e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  57 LARANLAGLNLVK---KGAphgfLLEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRWHNTRL 133
Cdd:COG1357   94 LSGANLSGANLRGanlSGA----NLSGADLSGADLSGANLSGADLSGANLSGANLSGADLSGADLSGANLSGANLSGANL 169


                 ....
gi 516375653 134 DNLD 137
Cdd:COG1357  170 ANLE 173
Pentapeptide pfam00805
Pentapeptide repeats (8 copies); These repeats are found in many cyanobacterial proteins. The ...
 81-123 3.13e-05

Pentapeptide repeats (8 copies); These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK. The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix. The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid.


Pssm-ID: 459943 [Multi-domain]  Cd Length: 40  Bit Score: 40.40  E-value: 3.13e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 516375653   81 CNLYRANLQGAHLYGLRMKGgslmkADLSDANLHCATLDDVNL 123
Cdd:pfam00805   1 ANLSGANLSGANLSGANLSG-----ANLTGANLSGADLSGANL 38
YjbI COG1357
Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];
78-135 1.07e-04

Uncharacterized conserved protein YjbI, contains pentapeptide repeats [Function unknown];


Pssm-ID: 440968 [Multi-domain]  Cd Length: 178  Bit Score: 42.24  E-value: 1.07e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516375653  78 LEQCNLYRANLQGAHLYGLRMKG----GSLMKADLSDANLHCATLDDVNLLGIRWHNTRLDN 135
Cdd:COG1357    2 LSGADLSGADLSGADLSGADLSGanlsGALSGANLSGANLSGANLTGANLSGADLSGADLSG 63
Ion_trans pfam00520
Ion transport protein; This family contains sodium, potassium and calcium ion channels. This ...
 223-315 2.16e-04

Ion transport protein; This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.


Pssm-ID: 459842 [Multi-domain]  Cd Length: 238  Bit Score: 41.87  E-value: 2.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  223 MRVVLFSLLLIFICSL-FYFFFGLSFNGNHLVYRPGAPFEQnaifLLECLYYSVVTFTTLGYGDFTPVGLSR-------- 293
Cdd:pfam00520 130 GNLLLLLLLFLFIFAIiGYQLFGGKLKTWENPDNGRTNFDN----FPNAFLWLFQTMTTEGWGDIMYDTIDGkgefwayi 205

                          90       100
                  ....*....|....*....|..
gi 516375653  294 IFAAFEAFTGSFTLALFVVVFV 315
Cdd:pfam00520 206 YFVSFIILGGFLLLNLFIAVII 227
PRK15196 PRK15196
type III secretion system effector PipB2;
54-137 7.47e-04

type III secretion system effector PipB2;


Pssm-ID: 185118 [Multi-domain]  Cd Length: 350  Bit Score: 40.76  E-value: 7.47e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  54 GLQLARANLAGLNLvKKGAPHGFLLEQCNLY-----RANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRW 128
Cdd:PRK15196 221 GATLDHANLTGANL-QHASLLGCSMIECNCSganmdHTNLSGATLIRADMSGATLQGATIMAAIMEGAVLTRANLRKASF 299


                 ....*....
gi 516375653 129 HNTRLDNLD 137
Cdd:PRK15196 300 ISTNLDGAD 308
PRK15196 PRK15196
type III secretion system effector PipB2;
52-133 9.76e-04

type III secretion system effector PipB2;


Pssm-ID: 185118 [Multi-domain]  Cd Length: 350  Bit Score: 40.37  E-value: 9.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  52 CHGLQLARANLAGLNLVK--------KGAP-HGFLLEQCNLYRANLQGAHLYGLRMKGgslmkADLSDANLHCATLDDVN 122
Cdd:PRK15196 249 CSGANMDHTNLSGATLIRadmsgatlQGATiMAAIMEGAVLTRANLRKASFISTNLDG-----ADLAEANLNNTCFKDCT 323

                         90
                 ....*....|.
gi 516375653 123 LLGIRWHNTRL 133
Cdd:PRK15196 324 LTHLRTEDATM 334
PRK15197 PRK15197
type III secretion system effector PipB;
41-125 1.01e-03

type III secretion system effector PipB;


Pssm-ID: 185119 [Multi-domain]  Cd Length: 291  Bit Score: 40.30  E-value: 1.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  41 ELEHYVHQGGLCHGLQLARANLAGLNLvkkgaphgfllEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDD 120
Cdd:PRK15197 160 NLAHKDFQGEDLSDIDASNADFRETTL-----------SNVNLVGANLCCANLHAVNLMGSNMTKANLTHADLTCANMSG 228


                 ....*
gi 516375653 121 VNLLG 125
Cdd:PRK15197 229 VNLTA 233
PRK15196 PRK15196
type III secretion system effector PipB2;
48-133 3.48e-03

type III secretion system effector PipB2;


Pssm-ID: 185118 [Multi-domain]  Cd Length: 350  Bit Score: 38.83  E-value: 3.48e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516375653  48 QGGLCHGLQLARANLAGLNLvkKGAP-HGFLLEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGI 126
Cdd:PRK15196 155 KGAVLTGANLTAENLCDADL--SGANlEGAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGA 232


                 ....*..
gi 516375653 127 RWHNTRL 133
Cdd:PRK15196 233 NLQHASL 239
Pentapeptide_4 pfam13599
Pentapeptide repeats (9 copies);
78-136 5.20e-03

Pentapeptide repeats (9 copies);


Pssm-ID: 433339 [Multi-domain]  Cd Length: 78  Bit Score: 35.33  E-value: 5.20e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 516375653   78 LEQCNLYRANLQGAHLYGLRMKGGSLMKADLSDANLHCATLDDVNLLGIRWHNTRLDNL 136
Cdd:pfam13599   8 FEGCKLSGTEFYHATLKDCNFTECNLVNVNFDDCNLRDVDFLEAQLKNAQFSGCNLKNS 66
PRK15197 PRK15197
type III secretion system effector PipB;
57-123 5.27e-03

type III secretion system effector PipB;


Pssm-ID: 185119 [Multi-domain]  Cd Length: 291  Bit Score: 37.99  E-value: 5.27e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516375653  57 LARANLAGLNLvkkgapHGFLLEQCNLYRANLQGAHLYGLRMKGGSLMKA-----DLSDANLHCATLDDVNL 123
Cdd:PRK15197 191 LVGANLCCANL------HAVNLMGSNMTKANLTHADLTCANMSGVNLTAAilfgsDLTDTKLNGAKLDKIAL 256
Pentapeptide pfam00805
Pentapeptide repeats (8 copies); These repeats are found in many cyanobacterial proteins. The ...
 78-110 5.81e-03

Pentapeptide repeats (8 copies); These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK. The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix. The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid.


Pssm-ID: 459943 [Multi-domain]  Cd Length: 40  Bit Score: 34.24  E-value: 5.81e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 516375653   78 LEQCNLYRANLQGAHLYGLRMKGGSLMKADLSD 110
Cdd:pfam00805   8 LSGANLSGANLSGANLTGANLSGADLSGANLSG 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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