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Conserved domains on  [gi|516413233|ref|WP_017802631|]
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MULTISPECIES: formate hydrogenlyase complex iron-sulfur subunit [Erwinia]

Protein Classification

formate hydrogenlyase complex iron-sulfur subunit( domain architecture ID 11485882)

formate hydrogenlyase complex iron-sulfur subunit is a 4Fe-4S dicluster domain-containing protein that may function as an electron transfer protein for the hydrogenase

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 1-183 4.03e-98

formate hydrogenlyase complex iron-sulfur subunit; Provisional


:

Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 281.15  E-value: 4.03e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233   1 MLKLIKKVLKTGTATLGYPFKPLNLAPNFRGKPHYTAQQCIACGACANACPSNALTMTTSDDTKTIRWQLFLGRCIFCAR 80
Cdd:PRK12387   1 MFKLIKKVIKTGTATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  81 CEEVCPTAAITLSQEFELAVWRKEDLFETADFPVCPCRECGKPYAVQKEIDFALSLLQENaalSDLQISERRVQYETCPA 160
Cdd:PRK12387  81 CEEVCPTAAIKLSQEFELAVWKKEDLLQQSEFALCNCRVCGRPFAVQKEIDYAIALLKHN---GDSRAENHRESFETCPE 157

                        170       180
                 ....*....|....*....|...
gi 516413233 161 CKKMHGLSPSDRIDIGRHMTTEV 183
Cdd:PRK12387 158 CKRQKCLVPSDRIELTRHMKEAI 180
 
Name Accession Description Interval E-value
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 1-183 4.03e-98

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 281.15  E-value: 4.03e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233   1 MLKLIKKVLKTGTATLGYPFKPLNLAPNFRGKPHYTAQQCIACGACANACPSNALTMTTSDDTKTIRWQLFLGRCIFCAR 80
Cdd:PRK12387   1 MFKLIKKVIKTGTATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  81 CEEVCPTAAITLSQEFELAVWRKEDLFETADFPVCPCRECGKPYAVQKEIDFALSLLQENaalSDLQISERRVQYETCPA 160
Cdd:PRK12387  81 CEEVCPTAAIKLSQEFELAVWKKEDLLQQSEFALCNCRVCGRPFAVQKEIDYAIALLKHN---GDSRAENHRESFETCPE 157

                        170       180
                 ....*....|....*....|...
gi 516413233 161 CKKMHGLSPSDRIDIGRHMTTEV 183
Cdd:PRK12387 158 CKRQKCLVPSDRIELTRHMKEAI 180
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-107 2.20e-23

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 89.40  E-value: 2.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233   15 TLGYPFKPLNLAPNFRGKPHYT-----AQQCIACGACANACPSNALTMTTSDD----TKTIRWQLFLGRCIFCARCEEVC 85
Cdd:TIGR01971  15 TVQYPEEKLYLPPRFRGRIVLTrdpngEEKCIGCTLCAAVCPADAIRVVPAEGedgkRRLKFYEINFGRCIFCGLCEEAC 94

                          90       100
                  ....*....|....*....|..
gi 516413233   86 PTAAITLSQEFELAVWRKEDLF 107
Cdd:TIGR01971  95 PTDAIVLTPEFELATYTRSDLV 116
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 40-105 1.19e-17

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 72.86  E-value: 1.19e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  40 CIACGACANACPSNALTMTtsDDTKTIRWQLFLGRCIFCARCEEVCPTAAITLSQeFELAVWRKED 105
Cdd:COG1143    4 CIGCGLCVRVCPVDAITIE--DGEPGKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 39-120 7.57e-15

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 67.42  E-value: 7.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  39 QCIACGACANACPSNALTMTTSDDTKTiRWQLFLGRCIFCARCEEVCPTAAITLSQEF-ELAVWRKEDLFetaDFPVC-P 116
Cdd:cd10549    7 KCIGCGICVKACPTDAIELGPNGAIAR-GPEIDEDKCVFCGACVEVCPTGAIELTPEGkEYVPKEKEAEI---DEEKCiG 82


                 ....
gi 516413233 117 CREC 120
Cdd:cd10549   83 CGLC 86
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 40-89 1.47e-10

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 54.07  E-value: 1.47e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 516413233   40 CIACGACANACPSNALTMTTSDDTKTI-RWQLFLGRCIFCARCEEVCPTAA 89
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTkTVVIDPERCVGCGACVAVCPTGA 51
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 40-90 2.07e-07

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 49.09  E-value: 2.07e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 516413233  40 CIACGACANACPSNALTMTtsdDTKtIRWQlflGRCIFCARCEEVCPTAAI 90
Cdd:NF038196 187 CIGCGICAKVCPVNNIEME---DGK-PVWG---HNCTHCLACIHRCPKEAI 230
 
Name Accession Description Interval E-value
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 1-183 4.03e-98

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 281.15  E-value: 4.03e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233   1 MLKLIKKVLKTGTATLGYPFKPLNLAPNFRGKPHYTAQQCIACGACANACPSNALTMTTSDDTKTIRWQLFLGRCIFCAR 80
Cdd:PRK12387   1 MFKLIKKVIKTGTATSSYPLEPIAVDKNFRGKPEYNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  81 CEEVCPTAAITLSQEFELAVWRKEDLFETADFPVCPCRECGKPYAVQKEIDFALSLLQENaalSDLQISERRVQYETCPA 160
Cdd:PRK12387  81 CEEVCPTAAIKLSQEFELAVWKKEDLLQQSEFALCNCRVCGRPFAVQKEIDYAIALLKHN---GDSRAENHRESFETCPE 157

                        170       180
                 ....*....|....*....|...
gi 516413233 161 CKKMHGLSPSDRIDIGRHMTTEV 183
Cdd:PRK12387 158 CKRQKCLVPSDRIELTRHMKEAI 180
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 1-168 5.54e-73

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 217.70  E-value: 5.54e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233   1 MLKLIKKVLKTGTATLGYPFKPLNLAPNFRGKPHYTAQQCIACGACANACPSNALTMTTSDDTKTIRWQLFLGRCIFCAR 80
Cdd:PRK08222   1 MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACTCACPANALTIQTDDQQNSRTWQLYLGRCIYCGR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  81 CEEVCPTAAITLSQEFELAVWRKEDLFETADFPVCPCRECGKPYAVQKEIDFALSLLQEnAALSDLQISERRVQYETCPA 160
Cdd:PRK08222  81 CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQ-QQNAPQNREMLRAQASVCPE 159


                 ....*...
gi 516413233 161 CKKMHGLS 168
Cdd:PRK08222 160 CKQRATLI 167
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
14-107 2.14e-27

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 101.11  E-value: 2.14e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  14 ATLGYPFKPLNLAPNFRGKPHYT-----AQQCIACGACANACPSNALTMTTSDDT----KTIRWQLFLGRCIFCARCEEV 84
Cdd:PRK05888  29 VTIQYPEEKLPLSPRFRGRHALRrdpngEERCIACKLCAAICPADAITIEAAEREdgrrRTTRYDINFGRCIFCGFCEEA 108

                         90       100
                 ....*....|....*....|...
gi 516413233  85 CPTAAITLSQEFELAVWRKEDLF 107
Cdd:PRK05888 109 CPTDAIVETPDFELATETREELI 131
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-107 2.20e-23

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 89.40  E-value: 2.20e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233   15 TLGYPFKPLNLAPNFRGKPHYT-----AQQCIACGACANACPSNALTMTTSDD----TKTIRWQLFLGRCIFCARCEEVC 85
Cdd:TIGR01971  15 TVQYPEEKLYLPPRFRGRIVLTrdpngEEKCIGCTLCAAVCPADAIRVVPAEGedgkRRLKFYEINFGRCIFCGLCEEAC 94

                          90       100
                  ....*....|....*....|..
gi 516413233   86 PTAAITLSQEFELAVWRKEDLF 107
Cdd:TIGR01971  95 PTDAIVLTPEFELATYTRSDLV 116
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 40-105 1.19e-17

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 72.86  E-value: 1.19e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  40 CIACGACANACPSNALTMTtsDDTKTIRWQLFLGRCIFCARCEEVCPTAAITLSQeFELAVWRKED 105
Cdd:COG1143    4 CIGCGLCVRVCPVDAITIE--DGEPGKVYVIDPDKCIGCGLCVEVCPTGAISMTP-FELAVEDREE 66
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 1-105 1.50e-16

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 71.79  E-value: 1.50e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233   1 MLKLIKKVLKTGT---ATLGYPFK-PLNLAPNFRGKPHYTAQQCIACGACANACPSNALTMTTsdDTKTIRwqLFLGRCI 76
Cdd:PRK08348   1 RLPLLPTVLRNLFkkpATNLFPATePVPVPEDFRGKILYDVDKCVGCRMCVTVCPAGVFVYLP--EIRKVA--LWTGRCV 76

                         90       100
                 ....*....|....*....|....*....
gi 516413233  77 FCARCEEVCPTAAITLSQEFELAVWRKED 105
Cdd:PRK08348  77 FCGQCVDVCPTGALQMSDDFLLASYDRFD 105
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 39-120 7.57e-15

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 67.42  E-value: 7.57e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  39 QCIACGACANACPSNALTMTTSDDTKTiRWQLFLGRCIFCARCEEVCPTAAITLSQEF-ELAVWRKEDLFetaDFPVC-P 116
Cdd:cd10549    7 KCIGCGICVKACPTDAIELGPNGAIAR-GPEIDEDKCVFCGACVEVCPTGAIELTPEGkEYVPKEKEAEI---DEEKCiG 82


                 ....
gi 516413233 117 CREC 120
Cdd:cd10549   83 CGLC 86
ndhI CHL00014
NADH dehydrogenase subunit I
 15-106 2.23e-14

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 67.09  E-value: 2.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  15 TLGYPFKPLNLAPNFRGKPHYTAQQCIACGACANACPSNaLTMTTSDDTKTIRWQLFL------GRCIFCARCEEVCPTA 88
Cdd:CHL00014  36 TIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPID-LPVVDWKLETDIRKKRLLnysidfGVCIFCGNCVEYCPTN 114

                         90
                 ....*....|....*...
gi 516413233  89 AITLSQEFELAVWRKEDL 106
Cdd:CHL00014 115 CLSMTEEYELSTYDRHEL 132
PRK13984 PRK13984
putative oxidoreductase; Provisional
 15-96 6.05e-12

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 63.25  E-value: 6.05e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  15 TLGYPFKPLNLAPNFRGKPHYTAQQCIACGACANACPSNALTM------TTSDDTKTIRWQLFLGRCIFCARCEEVCPTA 88
Cdd:PRK13984  22 TIKVPNVKREAAERYRGFHINDWEKCIGCGTCSKICPTDAITMvevpdlPQEYGKKPQRPVIDYGRCSFCALCVDICTTG 101


                 ....*...
gi 516413233  89 AITLSQEF 96
Cdd:PRK13984 102 SLKMTREY 109
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
31-103 8.49e-11

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 55.51  E-value: 8.49e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233  31 GKPHYTAQQCIACGACANACPSNALTMTtsDDTKTIrwqlFLGRCIFCARCEEVCPTAAITLSQEFELAVWRK 103
Cdd:COG2768    4 GKPYVDEEKCIGCGACVKVCPVGAISIE--DGKAVI----DPEKCIGCGACIEVCPVGAIKIEWEEDEEFQEK 70
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 40-89 1.47e-10

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 54.07  E-value: 1.47e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 516413233   40 CIACGACANACPSNALTMTTSDDTKTI-RWQLFLGRCIFCARCEEVCPTAA 89
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTkTVVIDPERCVGCGACVAVCPTGA 51
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 32-98 3.32e-10

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 53.52  E-value: 3.32e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 516413233  32 KPHYTAQQCIACGACANACPSNALTMttsdDTKTIRWqlFLGRCIFCARCEEVCPTAAITLSQEFEL 98
Cdd:COG2221    9 PPKIDEEKCIGCGLCVAVCPTGAISL----DDGKLVI--DEEKCIGCGACIRVCPTGAIKGEKPKKF 69
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 30-92 9.52e-10

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 52.42  E-value: 9.52e-10
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233  30 RGKPHYTAQQCIACGACANACPSNALTMTTSDdtktiRWQLFLGRCIFCARCEEVCPTAAITL 92
Cdd:COG1149    3 RKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGG-----APVVDPDLCTGCGACVGVCPTGAITL 60
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 40-97 4.49e-09

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 52.01  E-value: 4.49e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516413233  40 CIACGACANACPSNALTMTTsDDTKTIRWQLFL----GRCIFCARCEEVCPTAAITLSQEFE 97
Cdd:cd10549   42 CVFCGACVEVCPTGAIELTP-EGKEYVPKEKEAeideEKCIGCGLCVKVCPVDAITLEDELE 102
NapF COG1145
Ferredoxin [Energy production and conversion];
37-92 1.30e-08

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 52.80  E-value: 1.30e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  37 AQQCIACGACANACPSNALTMttSDDTKTIrwQLFLGRCIFCARCEEVCPTAAITL 92
Cdd:COG1145  181 AEKCIGCGLCVKVCPTGAIRL--KDGKPQI--VVDPDKCIGCGACVKVCPVGAISL 232
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 40-93 2.42e-08

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 50.09  E-value: 2.42e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 516413233  40 CIACGACANACPSNALTMTTSDDTKTIRwqlflGRCIFCARCEEVCPTAAITLS 93
Cdd:cd10549   80 CIGCGLCVKVCPVDAITLEDELEIVIDK-----EKCIGCGICAEVCPVNAIKLV 128
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
32-97 3.02e-08

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 51.60  E-value: 3.02e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  32 KPHYTAQQCIACGACANACPSNAltmttsDDTKTIRWQLflgRCIFCARCEEVCPTAAITLSQEFE 97
Cdd:COG0348  204 RVRYDRGDCIDCGLCVKVCPMGI------DIRKGEINQS---ECINCGRCIDACPKDAIRFSSRGE 260
Fer4_9 pfam13187
4Fe-4S dicluster domain;
39-90 4.72e-08

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 47.55  E-value: 4.72e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 516413233   39 QCIACGACANACPSNAltMTTSDDTKTIRWQLFLGRCIFCARCEEVCPTAAI 90
Cdd:pfam13187   1 KCTGCGACVAACPAGA--IVPDLVGQTIRGDIAGLACIGCGACVDACPRGAI 50
Rama_corrin_act TIGR04270
methylamine methyltransferase corrinoid protein reductive activase; Members of this family ...
 40-96 1.37e-07

methylamine methyltransferase corrinoid protein reductive activase; Members of this family occur as paralogs in species capable of generating methane from mono-, di-, and tri-methylamine. Members include RamA (Reductive Activation of Methyltransfer, Amines) from Methanosarcina barkeri MS (DSM 800). Member proteins have two C-terminal motifs with four Cys each, likely to bind one 4Fe-4S cluster per motif.


Pssm-ID: 211993 [Multi-domain]  Cd Length: 535  Bit Score: 50.53  E-value: 1.37e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 516413233   40 CIACGACANACPSNALTMTtSDDTKTIRWQLFLGRCifCARCEEVCPTAAITLSQEF 96
Cdd:TIGR04270 481 CIACQKCVKECPGKALSIL-ESEPPRIDTDRCLGTA--CRRCERVCPEKVFDIRNFF 534
PRK06273 PRK06273
ferredoxin; Provisional
 40-86 1.63e-07

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 48.55  E-value: 1.63e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 516413233  40 CIACGACANACPSNALTMT-------TSDDTKTIRWQLFLGRCIFCARCEEVCP 86
Cdd:PRK06273  51 CIGCGGCANVCPTKAIEMIpvepvkiTEGYVKTKIPKIDYEKCVYCLYCHDFCP 104
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
30-118 1.75e-07

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 48.11  E-value: 1.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  30 RGKPHYTAQQCIAC--GACANACPSNALTMTTSddtktiRWQLFLGRCIFCARCEEVCPTAAITLSQEFELAVWRKEDL- 106
Cdd:COG1142   42 RKAGVSAPVQCRHCedAPCAEVCPVGAITRDDG------AVVVDEEKCIGCGLCVLACPFGAITMVGEKSRAVAVKCDLc 115

                         90
                 ....*....|....*.
gi 516413233 107 FETADFP----VCPCR 118
Cdd:COG1142  116 GGREGGPacveACPTG 131
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 37-95 1.82e-07

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 46.24  E-value: 1.82e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516413233  37 AQQCIACGACANACPSNALTMtTSDDTKT--IRWQLflgrCIFCARCEEVCPTAAITLSQE 95
Cdd:COG1146    7 TDKCIGCGACVEVCPVDVLEL-DEEGKKAlvINPEE----CIGCGACELVCPVGAITVEDD 62
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 40-90 2.07e-07

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 49.09  E-value: 2.07e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 516413233  40 CIACGACANACPSNALTMTtsdDTKtIRWQlflGRCIFCARCEEVCPTAAI 90
Cdd:NF038196 187 CIGCGICAKVCPVNNIEME---DGK-PVWG---HNCTHCLACIHRCPKEAI 230
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 32-97 2.10e-07

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 46.58  E-value: 2.10e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  32 KPHYTAQQCIACGACANACPSNALTMttsDDTKTIrwQLFLGRCIFCARCEEVCPTAAITLSQEFE 97
Cdd:COG1144   24 RPVVDEDKCIGCGLCWIVCPDGAIRV---DDGKYY--GIDYDYCKGCGICAEVCPVKAIEMVPEEK 84
PRK13795 PRK13795
hypothetical protein; Provisional
 37-88 4.06e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 48.84  E-value: 4.06e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 516413233  37 AQQCIACGACANACPSNALTMttsdDTKTIRWQLFLGRCIFCARCEEVCPTA 88
Cdd:PRK13795 580 AAECVGCGVCVGACPTGAIRI----EEGKRKISVDEEKCIHCGKCTEVCPVV 627
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 40-90 1.52e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 45.71  E-value: 1.52e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  40 CIACGACANACPSNALTMTTSDDTKTIRWQLFL----GRCIFCA-RCEEVCPTAAI 90
Cdd:cd16373   16 CIRCGLCVEACPTGVIQPAGLEDGLEGGRTPYLdpreGPCDLCCdACVEVCPTGAL 71
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 40-92 2.40e-06

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 43.49  E-value: 2.40e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 516413233  40 CIACGACANACPSNALTMttSDDTKTIRWQLflgrCIFCARCEEVCPTAAITL 92
Cdd:COG4231   24 CTGCGACVKVCPADAIEE--GDGKAVIDPDL----CIGCGSCVQVCPVDAIKL 70
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
40-102 3.53e-06

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 46.17  E-value: 3.53e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233  40 CIACGACANACPSNALTMttSDDTKTIRwqlfLGRCIFCARCEEVCPTAAITLSQEFElAVWR 102
Cdd:COG4624   93 CKNCYPCVRACPVKAIKV--DDGKAEID----EEKCISCGQCVAVCPFGAITEKSDIE-KVKK 148
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
38-92 1.25e-05

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 43.11  E-value: 1.25e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516413233  38 QQCIACGACANACPSNALTMTTSDDTKTIRwqlflgRCIFCA------RCEEVCPTAAITL 92
Cdd:COG1142   81 EKCIGCGLCVLACPFGAITMVGEKSRAVAV------KCDLCGgreggpACVEACPTGALRL 135
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 35-87 1.54e-05

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 44.32  E-value: 1.54e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 516413233  35 YTAQQCIACGACANACP-----SNALTMTTSDDTKTIRwQLFlGRCIFCARCEEVCPT 87
Cdd:cd01916  362 ELAAKCTDCGWCTRACPnslriKEAMEAAKEGDFSGLA-DLF-DQCVGCGRCEQECPK 417
Fer4_16 pfam13484
4Fe-4S double cluster binding domain;
40-86 4.17e-05

4Fe-4S double cluster binding domain;


Pssm-ID: 463893 [Multi-domain]  Cd Length: 65  Bit Score: 39.78  E-value: 4.17e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233   40 CIACGACANACPSNALTMT----------------TSDDTKTIRWQLFLGRCIFCARCEEVCP 86
Cdd:pfam13484   1 CGSCGKCIDACPTGAIVGPegvldarrcisyltieKKGLIPDELRCLLGNRCYGCDICQDVCP 63
PRK09898 PRK09898
ferredoxin-like protein;
38-92 4.34e-05

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 42.52  E-value: 4.34e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 516413233  38 QQCIACGACANACPSNALTMTTSDDTKTirwqlflgRCIFCARCEEVCPTAAITL 92
Cdd:PRK09898 154 KRCIGCSACTTACPWMMATVNTESKKSS--------KCVLCGECANACPTGALKI 200
LutB COG1139
L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and ...
 39-86 5.41e-05

L-lactate utilization protein LutB, contains a ferredoxin-type domain [Energy production and conversion];


Pssm-ID: 440754 [Multi-domain]  Cd Length: 465  Bit Score: 42.79  E-value: 5.41e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 516413233  39 QCIACGACANACP-------------------SNaLTMTTS--DDTKTIrwqLFLgrCIFCARCEEVCP 86
Cdd:COG1139  312 RCIRCGACLNVCPvyrrvgghaygsvypgpigAV-LTPLLHglEKAADL---PYA--STLCGACTEVCP 374
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
40-90 5.44e-05

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 42.23  E-value: 5.44e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 516413233  40 CIACGACANACPSNALTMTTS----DDTKtirwqlflgrCIFCARCEEVCPTAAI 90
Cdd:PRK07118 215 CIGCGKCVKACPAGAITMENNlaviDQEK----------CTSCGKCVEKCPTKAI 259
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 38-95 5.84e-05

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 41.08  E-value: 5.84e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 516413233  38 QQCIACGACANACPSNALTMTtSDDTKTIRWQLflGRCIFCARCEEVCPTAAITLSQE 95
Cdd:cd10564   13 DLCTRCGDCVEACPEGIIVRG-DGGFPELDFSR--GECTFCGACAEACPEGALDPARE 67
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 32-86 6.05e-05

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 39.16  E-value: 6.05e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 516413233   32 KPHYTAQQCIACGACANACPSNALTMTTS---DDTKTIRWqlFLGRCIFCARCEEVCP 86
Cdd:pfam13237   1 KVVIDPDKCIGCGRCTAACPAGLTRVGAIverLEGEAVRI--GVWKCIGCGACVEACP 56
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 40-91 6.58e-05

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 41.08  E-value: 6.58e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  40 CIACGACANACPSNALtmttsDDTKTIRWQL---FLGRC-----IFCARCEEVCPTAAIT 91
Cdd:cd10564   47 CTFCGACAEACPEGAL-----DPAREAPWPLraeIGDSClalqgVECRSCQDACPTQAIR 101
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 39-86 7.22e-05

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 42.37  E-value: 7.22e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  39 QCIACGACANACPSNALTMTTSDDTK------------------TIRWQLFLGRCIFCARCEEVCP 86
Cdd:COG0247   79 ACVGCGFCRAMCPSYKATGDEKDSPRgrinllrevlegelpldlSEEVYEVLDLCLTCKACETACP 144
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 27-90 8.53e-05

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 39.93  E-value: 8.53e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 516413233   27 PNFRGKPHYTAQQCIACGACANACPSNALTMTTSdDTKTIRWQlfLGRCIFCARCEEVCPTAAI 90
Cdd:TIGR00402  23 PPWSARESLFSAVCTRCGECASACENNILQLGQQ-GQPTVEFD--NAECDFCGKCAEACPTNAF 83
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
 33-99 9.58e-05

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 42.05  E-value: 9.58e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233  33 PHYTAQQCIACGACANACPSNAL-----TMTTSDDT-KTIRWQLFLgrCIFCARCEEVCPtAAITLSQEFELA 99
Cdd:COG4656  359 PPPEEQPCIRCGRCVDACPMGLLpqqlyWYARAGDFdKAEEYNLMD--CIECGCCSYVCP-SKIPLVQYIRLA 428
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
31-92 1.15e-04

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 41.46  E-value: 1.15e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233  31 GKPHYTAQQCIACGACANACPSNALTMT-----------TSDDTKTIRWQLFLGrCIFCARCEEVCPTAAITL 92
Cdd:PRK07118 161 GLPVVDEDKCTGCGACVKACPRNVIELIpksarvfvacnSKDKGKAVKKVCEVG-CIGCGKCVKACPAGAITM 232
psaC CHL00065
photosystem I subunit VII
 40-87 1.75e-04

photosystem I subunit VII


Pssm-ID: 177005 [Multi-domain]  Cd Length: 81  Bit Score: 38.59  E-value: 1.75e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 516413233  40 CIACGACANACPSNALTMTTSDDTKT--IRWQLFLGRCIFCARCEEVCPT 87
Cdd:CHL00065  11 CIGCTQCVRACPTDVLEMIPWDGCKAkqIASAPRTEDCVGCKRCESACPT 60
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 40-91 2.64e-04

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 39.29  E-value: 2.64e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516413233  40 CIACGACANACPSNALTMTTSD-------DTKTIRWQLFLGRCIFC--ARCEEVCPTAAIT 91
Cdd:cd04410    8 CIGCGTCEVACKQEHGLRPGPDwsrikviEGGGLERAFLPVSCMHCedPPCVKACPTGAIY 68
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 40-92 2.76e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 39.10  E-value: 2.76e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  40 CIACGACANACPSNAltMTTSDDTKTIRwqlflgRCIFCA---RCEEVCPTAAITL 92
Cdd:cd10550   82 CIGCGMCVEACPFGA--IRVDPETGKAI------KCDLCGgdpACVKVCPTGALEF 129
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 33-86 3.39e-04

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 40.32  E-value: 3.39e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 516413233  33 PHYTAQQCIACGACANACPSNALTMttsddtktirwQLF---------------LGRCIFCARCEEVCP 86
Cdd:PRK05035 365 PPPPEQPCIRCGACADACPASLLPQ-----------QLYwfakaeehdkaqeynLFDCIECGACAYVCP 422
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
38-92 3.47e-04

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 40.23  E-value: 3.47e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 516413233  38 QQCIACGACANACPSNALTMttsDDTKTIrwQLFLGRCIFCARCEEVCPTAAITL 92
Cdd:COG1148  496 EKCTGCGRCVEVCPYGAISI---DEKGVA--EVNPALCKGCGTCAAACPSGAISL 545
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 40-91 3.85e-04

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 39.54  E-value: 3.85e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516413233  40 CIACGACANACPSNALTMttSDDTKTIRwqlflgRCIFCA---------RCEEVCPTAAIT 91
Cdd:COG0437   92 CIGCRYCVAACPYGAPRF--NPETGVVE------KCTFCAdrldegllpACVEACPTGALV 144
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 37-110 3.94e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 40.12  E-value: 3.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  37 AQQCIACGACANACPSNALTM-TTSDDTKTIRWQLFlgRCIFCA------RCEEVCPTAAITLSQEFELAVWRKEDLFET 109
Cdd:PRK12769  84 QQKCIGCKSCVVACPFGTMQIvLTPVAAGKVKATAH--KCDLCAgrengpACVENCPADALQLVTEQALSGMAKSRRLRT 161


                 .
gi 516413233 110 A 110
Cdd:PRK12769 162 A 162
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 34-95 5.89e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 39.47  E-value: 5.89e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 516413233  34 HYTAQQCIACG------ACANACPSNALTmttsdDTKTIRWQLF-LGRCIFCARCEEVCPTAAITLSQE 95
Cdd:PRK12771 500 RQEAARCLSCGncfecdNCYGACPQDAII-----KLGPGRRYHFdYDKCTGCHICADVCPCGAIEMGPG 563
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
19-92 7.09e-04

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 39.16  E-value: 7.09e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 516413233  19 PFKPLNLapNFRGKPHYTAQQCIACGACANACPSNALTMTTSDDTKTIRWQLFLGRCIFCARCEEVCPTA-AITL 92
Cdd:PRK08318 325 DWEDLDL--NYIVYARIDQDKCIGCGRCYIACEDTSHQAIEWDEDGTRTPEVIEEECVGCNLCAHVCPVEgCITM 397
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 40-92 8.28e-04

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 37.75  E-value: 8.28e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516413233  40 CIACGACANACPSNALTMTTSDdtktirwqLFLGRCIFCA---------RCEEVCPTAAITL 92
Cdd:cd04410   82 CIGCGSCVEACPYGAIVFDPEP--------GKAVKCDLCGdrldeglepACVKACPTGALTF 135
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 18-118 8.35e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 39.24  E-value: 8.35e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  18 YPFKPLNLAPNFRGKPHYTAQQCIACGACANA-----CPSNALTMTTSDdtktirWQLFLGRCIFCARCEEVCPTAAI-- 90
Cdd:PRK12809  31 WPLSHSDFRPRIHVVGKGQAANPVACHHCNNApcvtaCPVNALTFQSDS------VQLDEQKCIGCKRCAIACPFGVVem 104

                         90       100       110
                 ....*....|....*....|....*....|
gi 516413233  91 --TLSQEFELAVWRKEDlfETADFPVCPCR 118
Cdd:PRK12809 105 vdTIAQKCDLCNQRSSG--TQACIEVCPTQ 132
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 40-92 8.59e-04

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 38.82  E-value: 8.59e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 516413233  40 CIACGACANACPSNALTMT-----TSDDTKtirwqlflgrCIFCARCEEVCPTAAITL 92
Cdd:COG2878  139 CIGCGDCIKACPFDAIVGAakgmhTVDEDK----------CTGCGLCVEACPVDCIEM 186
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 37-91 1.23e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 37.62  E-value: 1.23e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 516413233  37 AQQCIACGACANACPSNALTMTTSDDTKtiRWQLFLGRCIFCARCEEVCPT---AAIT 91
Cdd:cd16373   96 WQGGTDCGVCVEACPTEAIAIVLEDDVL--RPVVDEDKCVGCGLCEYVCPVeppKAIV 151
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 34-92 1.31e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 37.25  E-value: 1.31e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 516413233  34 HYTAQQCIACGACANACPSNALTMTTSDDTKTIrwqlflgrCIFCARCEEVCPTAAITL 92
Cdd:cd16370   79 VLDKEKCIGCGNCVKACIVGAIFWDEETNKPII--------CIHCGYCARYCPHDVLAM 129
oorD PRK09626
2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed
 40-99 1.54e-03

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed


Pssm-ID: 236597 [Multi-domain]  Cd Length: 103  Bit Score: 36.62  E-value: 1.54e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233  40 CIACGACANACPSNALTMTtsDDTKTIRWQL----FLGRCIFCARCEEVCPTAAITLS--QEFELA 99
Cdd:PRK09626  18 CKACDICVSVCPAGVLAMR--IDPHAVLGKMikvvHPESCIGCRECELHCPDFAIYVAdrKEFKFA 81
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 40-92 1.65e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 36.93  E-value: 1.65e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 516413233  40 CIACGACANACPSNALTMTTSDDTKTirwqlflgRCIFCARCEEVCPTAAITL 92
Cdd:cd16372   79 CVGCLMCVGFCPEGAMFKHEDYPEPF--------KCIACGICVKACPTGALEL 123
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 32-67 1.77e-03

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 35.49  E-value: 1.77e-03
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 516413233  32 KPHYTAQQCIACGACANACPSNALTMTTSDDTKTIR 67
Cdd:COG1143   29 VYVIDPDKCIGCGLCVEVCPTGAISMTPFELAVEDR 64
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 35-95 1.80e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 36.79  E-value: 1.80e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233  35 YTAQQCIACG--ACANACPSNALTMttsdDTKTIRWQLFLGRCIFCARCEEVCPTAAITLSQE 95
Cdd:cd10550   44 DVPVVCRQCEdaPCVEACPVGAISR----DEETGAVVVDEDKCIGCGMCVEACPFGAIRVDPE 102
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 36-110 1.84e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 38.08  E-value: 1.84e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  36 TAQQCIACGACANACPSNALTMTTSDDTKtirwqlflgrCIFCAR-------CEEVCPTAAITLSQEFELAVWRKEDLFE 108
Cdd:PRK12809  83 DEQKCIGCKRCAIACPFGVVEMVDTIAQK----------CDLCNQrssgtqaCIEVCPTQALRLMDDKGLQQIKVARQRK 152


                 ..
gi 516413233 109 TA 110
Cdd:PRK12809 153 TA 154
PLN00071 PLN00071
photosystem I subunit VII; Provisional
 40-87 1.87e-03

photosystem I subunit VII; Provisional


Pssm-ID: 177700 [Multi-domain]  Cd Length: 81  Bit Score: 35.69  E-value: 1.87e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 516413233  40 CIACGACANACPSNALTMTTSDDTKT--IRWQLFLGRCIFCARCEEVCPT 87
Cdd:PLN00071  11 CIGCTQCVRACPTDVLEMIPWDGCKAkqIASAPRTEDCVGCKRCESACPT 60
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 43-98 1.94e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 37.23  E-value: 1.94e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 516413233  43 CGACANACPSNALTMTTSDDTKTI--RWQLFLGRCI------FCARCEEVCPTAAITLSQEFEL 98
Cdd:cd16373   59 CDACVEVCPTGALRPLDLEEQKVKmgVAVIDKDRCLawqggtDCGVCVEACPTEAIAIVLEDDV 122
dhsB TIGR00384
succinate dehydrogenase and fumarate reductase iron-sulfur protein; Succinate dehydrogenase ...
 40-87 2.81e-03

succinate dehydrogenase and fumarate reductase iron-sulfur protein; Succinate dehydrogenase and fumarate reductase are reverse directions of the same enzymatic interconversion, succinate + FAD+ = fumarate + FADH2 (EC 1.3.11.1). In E. coli, the forward and reverse reactions are catalyzed by distinct complexes: fumarate reductase operates under anaerobic conditions and succinate dehydrogenase operates under aerobic conditions. This model also describes a region of the B subunit of a cytosolic archaeal fumarate reductase. [Energy metabolism, Aerobic, Energy metabolism, Anaerobic, Energy metabolism, TCA cycle]


Pssm-ID: 273049 [Multi-domain]  Cd Length: 220  Bit Score: 37.02  E-value: 2.81e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 516413233   40 CIACGACANACPS----------NALTMT------TSDDTKTIRWQLF-----LGRCIFCARCEEVCPT 87
Cdd:TIGR00384 140 CILCGCCYSSCPAfwwnpeflgpAALTAAyrflidSRDHATKDRLEGLndkngVWRCTTCMNCSEVCPK 208
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 32-95 3.19e-03

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 37.28  E-value: 3.19e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516413233  32 KPHYTAQQCIACGACANACPSNALtMTTSDDTKTIRWQLFLGR--------CIFCARCEEVCPTAAITLSQE 95
Cdd:PRK14028 241 KPVIDHSKCIMCRKCWLYCPDDAI-IEAWREAEGPRGRKFRMKmidfdyqyCKGCGVCAEVCPTGAIQMVRE 311
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 40-91 3.20e-03

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 36.74  E-value: 3.20e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 516413233  40 CIACGACANACPSNALTMTTSDDTKTIRWQLFLGR----CIFCA---------RCEEVCPTAAIT 91
Cdd:cd10551   85 CIGCRYCMAACPYGARYFNPEEPHEFGEVPVRPKGvvekCTFCYhrldegllpACVEACPTGARI 149
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 33-58 3.48e-03

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 36.07  E-value: 3.48e-03
                         10        20
                 ....*....|....*....|....*.
gi 516413233  33 PHYTAQQCIACGACANACPSNALTMT 58
Cdd:cd10564  112 PELDADACTGCGACVSVCPVGAITLT 137
Fer4_17 pfam13534
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 40-86 4.15e-03

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 433287 [Multi-domain]  Cd Length: 61  Bit Score: 34.36  E-value: 4.15e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 516413233   40 CIACGACANACPSNALT---------MTTSDDTKTIRWQLFLGRCIFCARCEEVCP 86
Cdd:pfam13534   2 CIQCGCCVDECPRYLLNgdepkklmrAAYLGDLEELQANKVANLCSECGLCEYACP 57
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 36-100 4.56e-03

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 36.08  E-value: 4.56e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 516413233  36 TAQQCIAC--GACANACPSNALTMTtsDDTKTIRWQlflgRCIFCARCEEVCPTAAITLSQEFELAV 100
Cdd:cd10554   52 APVQCRQCedAPCANVCPVGAISQE--DGVVQVDEE----RCIGCKLCVLACPFGAIEMAPTTVPGV 112
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 40-93 5.24e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 36.40  E-value: 5.24e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 516413233  40 CIACGACANACPSNALTMttsDDTKTIRWQLFlgRCIFCARCEEVCPTAAITLS 93
Cdd:PRK00783 171 CDECEKCVEACPRGVLEL---KEGKLVVTDLL--NCSLCKLCERACPGKAIRVS 219
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
19-57 6.38e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 36.38  E-value: 6.38e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 516413233  19 PFKplnlAPNF--RGKPHYTAQQCIACGACANACPSNALTM 57
Cdd:COG1148  509 PYG----AISIdeKGVAEVNPALCKGCGTCAAACPSGAISL 545
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 74-102 7.15e-03

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 33.95  E-value: 7.15e-03
                         10        20
                 ....*....|....*....|....*....
gi 516413233  74 RCIFCARCEEVCPTAAITLSQEFELAVWR 102
Cdd:COG1143    3 KCIGCGLCVRVCPVDAITIEDGEPGKVYV 31
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
18-95 8.33e-03

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 34.54  E-value: 8.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516413233  18 YPFKPLNLAP---NFRG-----KPHYTAQQCIACGACANACPSNALTMTtSDDTKTIRWQLflgrCIFCARCEEVCPTAA 89
Cdd:PRK09623  23 YPEAPISLGTtlsNFTGdwrtfMPVVDESKCVKCYICWKFCPEPAIYIK-EDGYVAIDYDY----CKGCGICANECPTKA 97


                 ....*.
gi 516413233  90 ITLSQE 95
Cdd:PRK09623  98 ITMVKE 103
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 35-95 8.70e-03

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 35.06  E-value: 8.70e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516413233  35 YTAQQCIACG--ACANACPSNALTMttsDDTKTIRWQLflGRCIFCARCEEVCPTAAITLSQE 95
Cdd:cd04410   45 FLPVSCMHCEdpPCVKACPTGAIYK---DEDGIVLIDE--DKCIGCGSCVEACPYGAIVFDPE 102
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 40-56 9.02e-03

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 32.61  E-value: 9.02e-03
                          10
                  ....*....|....*..
gi 516413233   40 CIACGACANACPSNALT 56
Cdd:pfam00037   8 CIGCGACVEVCPVGAIT 24
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
40-64 9.48e-03

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 35.81  E-value: 9.48e-03
                         10        20
                 ....*....|....*....|....*
gi 516413233  40 CIACGACANACPSNALTMTTSDDTK 64
Cdd:COG0348  238 CINCGRCIDACPKDAIRFSSRGEKT 262
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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