|
Name |
Accession |
Description |
Interval |
E-value |
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
1-306 |
7.23e-93 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 278.27 E-value: 7.23e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 1 MIGIKSIASYVPADGIDNYAQGAKFAKDEEFIIGKIGSAFLPRKEAGQETSDLCVEAVNALFANNpQLKRESIDALIVVT 80
Cdd:cd00830 1 NARILGIGSYLPERVVTNDELEKRLDTSDEWIRTRTGIRERRIADPGETTSDLAVEAAKKALEDA-GIDADDIDLIIVAT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 81 QNGDEeGLPHTAAIVQDKLGLPtHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTMLFG 160
Cdd:cd00830 80 STPDY-LFPATACLVQARLGAK-NAAAFDINAACSGFLYGLSTAAGLIRSGGAKNVLVVGAETLSRILDWTDRSTAVLFG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 161 DAATATWMGE-DASWLLGKAKFGTDGSGAPHLKVS--------------DGVFFMNGRQVFNFALLKVPAHLHALLDESD 225
Cdd:cd00830 158 DGAGAVVLEAtEEDPGILDSVLGSDGSGADLLTIPaggsrspfedaeggDPYLVMDGREVFKFAVRLMPESIEEALEKAG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 226 LKADDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPLLLEKHALDSTWK---RVAISGFGVGLSWG 302
Cdd:cd00830 238 LTPDDIDWFVPHQANLRIIEAVAKRLG-LPEEKVVVNLDRYGNTSAASIPLALDEAIEEGKLKkgdLVLLLGFGAGLTWG 316
|
....
gi 516456528 303 SAIL 306
Cdd:cd00830 317 AALL 320
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
2-306 |
1.08e-81 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 250.03 E-value: 1.08e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 2 IGIKSIASYVPADGIDNYAQGAKFAKDEEFIIGKIGSAFLPRKEAGQETSDLCVEAVNALFANnPQLKRESIDALIVVTQ 81
Cdd:COG0332 3 VRILGTGSYLPERVVTNDDLEKRLDTSDEWIEERTGIRERRIAAPDETTSDLAVEAARKALEA-AGIDPEDIDLIIVATV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 82 NGDEEgLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTMLFGD 161
Cdd:COG0332 82 TPDYL-FPSTACLVQHKLGA-KNAAAFDINAACSGFVYALSVAAALIRSGQAKNVLVVGAETLSRIVDWTDRSTCVLFGD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 162 AATATWMG--EDASWLLGkAKFGTDGSGAPHLKVSDG--------------VFFMNGRQVFNFALLKVPAHLHALLDESD 225
Cdd:COG0332 160 GAGAVVLEasEEGPGILG-SVLGSDGSGADLLVVPAGgsrnppspvdegdhYLRMDGREVFKFAVRNLPEVIREALEKAG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 226 LKADDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPLLLEkHALDS----TWKRVAISGFGVGLSW 301
Cdd:COG0332 239 LTLDDIDWFIPHQANLRIIEAVAKRLG-LPEEKVVVNIDRYGNTSAASIPLALD-EALREgrikPGDLVLLAGFGAGLTW 316
|
....*
gi 516456528 302 GSAIL 306
Cdd:COG0332 317 GAAVL 321
|
|
| PRK09352 |
PRK09352 |
beta-ketoacyl-ACP synthase 3; |
2-306 |
5.56e-65 |
|
beta-ketoacyl-ACP synthase 3;
Pssm-ID: 236475 [Multi-domain] Cd Length: 319 Bit Score: 206.85 E-value: 5.56e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 2 IGIKSIASYVPADGIDNyaqgAKFAK----DEEFIIGKIGSAFLPRKEAGQETSDLCVEA-VNALfaNNPQLKRESIDAL 76
Cdd:PRK09352 4 AKILGTGSYLPERVVTN----DDLEKmvdtSDEWIVTRTGIKERRIAAPDETTSDLATEAaKKAL--EAAGIDPEDIDLI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 77 IVVTQNGDEeGLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTT 156
Cdd:PRK09352 78 IVATTTPDY-AFPSTACLVQARLGA-KNAAAFDLSAACSGFVYALSTADQFIRSGAYKNVLVIGAEKLSRIVDWTDRSTC 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 157 MLFGDAATATWMGEDASWLLGKAKFGTDGSGAPHLKVSDGV---------FFMNGRQVFNFALLKVPAHLHALLDESDLK 227
Cdd:PRK09352 156 VLFGDGAGAVVLGASEEPGILSTHLGSDGSYGDLLYLPGGGsrgpaspgyLRMEGREVFKFAVRELAKVAREALEAAGLT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 228 ADDIDAFCIHQGSAAIVDAVARRFeDAPVDKFIKDMVETGNTVSSSIPLLL----EKHALDSTwKRVAISGFGVGLSWGS 303
Cdd:PRK09352 236 PEDIDWLVPHQANLRIIDATAKKL-GLPMEKVVVTVDKYGNTSAASIPLALdeavRDGRIKRG-DLVLLEGFGGGLTWGA 313
|
...
gi 516456528 304 AIL 306
Cdd:PRK09352 314 ALV 316
|
|
| fabH |
TIGR00747 |
3-oxoacyl-(acyl-carrier-protein) synthase III; FabH in general initiate elongation in type II ... |
3-307 |
6.59e-46 |
|
3-oxoacyl-(acyl-carrier-protein) synthase III; FabH in general initiate elongation in type II fatty acid synthase systems found in bacteria and plants. The two members of this subfamily from Bacillus subtilis differ from each other, and from FabH from E. coli, in acyl group specificity. Active site residues include Cys112, His244 and Asn274 of E. coli FabH. Cys-112 is the site of acyl group attachment. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 273249 [Multi-domain] Cd Length: 318 Bit Score: 157.54 E-value: 6.59e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 3 GIKSIASYVPADGIDNyAQGAKFAK-DEEFIIGKIGsaFLPRKEAGQE--TSDLCVEAV-NALfaNNPQLKRESIDaLIV 78
Cdd:TIGR00747 4 GILGTGSYLPEKVLTN-ADLEKMVDtSDEWIVTRTG--IKERRIAADDetSSTMGFEAAkRAI--ENAGISKDDID-LII 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 79 VTQNGDEEGLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTML 158
Cdd:TIGR00747 78 VATTTPDHAFPSAACMVQAYLGI-KGIPAFDLSAACAGFIYALSVAKQYIESGKYKTVLVVGAEKLSSTLDWTDRGTCVL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 159 FGDAATATWMGE-DASWLLGKAKFGTDGSGAPHLKVSDGV---------FFMNGRQVFNFALLKVPAHLHALLDESDLKA 228
Cdd:TIGR00747 157 FGDGAGAVVLGEsEDPGGIISTHLGADGTQGEALYLPAGGrptsgpspfITMEGNEVFKHAVRKMGDVVEETLEANGLDP 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 229 DDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPL----LLEKHALDSTwKRVAISGFGVGLSWGSA 304
Cdd:TIGR00747 237 EDIDWFVPHQANLRIIEALAKRLE-LDMSQVVKTVHKYGNTSAASIPLaldeLLRTGRIKPG-DLLLLVAFGGGLTWGAA 314
|
...
gi 516456528 305 ILY 307
Cdd:TIGR00747 315 LVR 317
|
|
| ACP_syn_III_C |
pfam08541 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ... |
221-306 |
1.38e-24 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430060 Cd Length: 90 Bit Score: 94.88 E-value: 1.38e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 221 LDESDLKADDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPLLLEkHALDS----TWKRVAISGFG 296
Cdd:pfam08541 1 LEKAGLTPEDIDWFVPHQANLRIIDAVAKRLG-LPPEKVVVNLDEYGNTSAASIPLALD-EAVEEgklkPGDLVLLVGFG 78
|
90
....*....|
gi 516456528 297 VGLSWGSAIL 306
Cdd:pfam08541 79 AGLTWGAALL 88
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
1-306 |
7.23e-93 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 278.27 E-value: 7.23e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 1 MIGIKSIASYVPADGIDNYAQGAKFAKDEEFIIGKIGSAFLPRKEAGQETSDLCVEAVNALFANNpQLKRESIDALIVVT 80
Cdd:cd00830 1 NARILGIGSYLPERVVTNDELEKRLDTSDEWIRTRTGIRERRIADPGETTSDLAVEAAKKALEDA-GIDADDIDLIIVAT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 81 QNGDEeGLPHTAAIVQDKLGLPtHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTMLFG 160
Cdd:cd00830 80 STPDY-LFPATACLVQARLGAK-NAAAFDINAACSGFLYGLSTAAGLIRSGGAKNVLVVGAETLSRILDWTDRSTAVLFG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 161 DAATATWMGE-DASWLLGKAKFGTDGSGAPHLKVS--------------DGVFFMNGRQVFNFALLKVPAHLHALLDESD 225
Cdd:cd00830 158 DGAGAVVLEAtEEDPGILDSVLGSDGSGADLLTIPaggsrspfedaeggDPYLVMDGREVFKFAVRLMPESIEEALEKAG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 226 LKADDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPLLLEKHALDSTWK---RVAISGFGVGLSWG 302
Cdd:cd00830 238 LTPDDIDWFVPHQANLRIIEAVAKRLG-LPEEKVVVNLDRYGNTSAASIPLALDEAIEEGKLKkgdLVLLLGFGAGLTWG 316
|
....
gi 516456528 303 SAIL 306
Cdd:cd00830 317 AALL 320
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
2-306 |
1.08e-81 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 250.03 E-value: 1.08e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 2 IGIKSIASYVPADGIDNYAQGAKFAKDEEFIIGKIGSAFLPRKEAGQETSDLCVEAVNALFANnPQLKRESIDALIVVTQ 81
Cdd:COG0332 3 VRILGTGSYLPERVVTNDDLEKRLDTSDEWIEERTGIRERRIAAPDETTSDLAVEAARKALEA-AGIDPEDIDLIIVATV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 82 NGDEEgLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTMLFGD 161
Cdd:COG0332 82 TPDYL-FPSTACLVQHKLGA-KNAAAFDINAACSGFVYALSVAAALIRSGQAKNVLVVGAETLSRIVDWTDRSTCVLFGD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 162 AATATWMG--EDASWLLGkAKFGTDGSGAPHLKVSDG--------------VFFMNGRQVFNFALLKVPAHLHALLDESD 225
Cdd:COG0332 160 GAGAVVLEasEEGPGILG-SVLGSDGSGADLLVVPAGgsrnppspvdegdhYLRMDGREVFKFAVRNLPEVIREALEKAG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 226 LKADDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPLLLEkHALDS----TWKRVAISGFGVGLSW 301
Cdd:COG0332 239 LTLDDIDWFIPHQANLRIIEAVAKRLG-LPEEKVVVNIDRYGNTSAASIPLALD-EALREgrikPGDLVLLAGFGAGLTW 316
|
....*
gi 516456528 302 GSAIL 306
Cdd:COG0332 317 GAAVL 321
|
|
| PRK09352 |
PRK09352 |
beta-ketoacyl-ACP synthase 3; |
2-306 |
5.56e-65 |
|
beta-ketoacyl-ACP synthase 3;
Pssm-ID: 236475 [Multi-domain] Cd Length: 319 Bit Score: 206.85 E-value: 5.56e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 2 IGIKSIASYVPADGIDNyaqgAKFAK----DEEFIIGKIGSAFLPRKEAGQETSDLCVEA-VNALfaNNPQLKRESIDAL 76
Cdd:PRK09352 4 AKILGTGSYLPERVVTN----DDLEKmvdtSDEWIVTRTGIKERRIAAPDETTSDLATEAaKKAL--EAAGIDPEDIDLI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 77 IVVTQNGDEeGLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTT 156
Cdd:PRK09352 78 IVATTTPDY-AFPSTACLVQARLGA-KNAAAFDLSAACSGFVYALSTADQFIRSGAYKNVLVIGAEKLSRIVDWTDRSTC 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 157 MLFGDAATATWMGEDASWLLGKAKFGTDGSGAPHLKVSDGV---------FFMNGRQVFNFALLKVPAHLHALLDESDLK 227
Cdd:PRK09352 156 VLFGDGAGAVVLGASEEPGILSTHLGSDGSYGDLLYLPGGGsrgpaspgyLRMEGREVFKFAVRELAKVAREALEAAGLT 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 228 ADDIDAFCIHQGSAAIVDAVARRFeDAPVDKFIKDMVETGNTVSSSIPLLL----EKHALDSTwKRVAISGFGVGLSWGS 303
Cdd:PRK09352 236 PEDIDWLVPHQANLRIIDATAKKL-GLPMEKVVVTVDKYGNTSAASIPLALdeavRDGRIKRG-DLVLLEGFGGGLTWGA 313
|
...
gi 516456528 304 AIL 306
Cdd:PRK09352 314 ALV 316
|
|
| PRK12879 |
PRK12879 |
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed |
47-306 |
1.74e-50 |
|
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
Pssm-ID: 237245 [Multi-domain] Cd Length: 325 Bit Score: 169.66 E-value: 1.74e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 47 GQETSDLCVEAV-NALfaNNPQLKRESIDALIVVTQNGDEEgLPHTAAIVQDKLGLPtHVAAFDLSLGCSGYVYGIYAMK 125
Cdd:PRK12879 50 EEYTSDLAIKAAeRAL--ARAGLDAEDIDLIIVATTTPDYL-FPSTASQVQARLGIP-NAAAFDINAACAGFLYGLETAN 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 126 GFMEATGLKNGLLITADPYSKIVDPEDRNTTMLFGDAATATWMGEDASWL-LGKAKFGTDGSGAPHLKVS---------- 194
Cdd:PRK12879 126 GLITSGLYKKVLVIGAERLSKVTDYTDRTTCILFGDGAGAVVLEATENEPgFIDYVLGTDGDGGDILYRTglgttmdrda 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 195 ---DGVFFMNGRQVFNFALLKVPAHLHALLDESDLKADDIDAFCIHQGSAAIVDAVARRFeDAPVDKFIKDMVETGNTVS 271
Cdd:PRK12879 206 lsgDGYIVQNGREVFKWAVRTMPKGARQVLEKAGLTKDDIDWVIPHQANLRIIESLCEKL-GIPMEKTLVSVEYYGNTSA 284
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 516456528 272 SSIPLllekhALDSTWKRVAIS--------GFGVGLSWGSAIL 306
Cdd:PRK12879 285 ATIPL-----ALDLALEQGKIKpgdtlllyGFGAGLTWAALLV 322
|
|
| fabH |
TIGR00747 |
3-oxoacyl-(acyl-carrier-protein) synthase III; FabH in general initiate elongation in type II ... |
3-307 |
6.59e-46 |
|
3-oxoacyl-(acyl-carrier-protein) synthase III; FabH in general initiate elongation in type II fatty acid synthase systems found in bacteria and plants. The two members of this subfamily from Bacillus subtilis differ from each other, and from FabH from E. coli, in acyl group specificity. Active site residues include Cys112, His244 and Asn274 of E. coli FabH. Cys-112 is the site of acyl group attachment. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 273249 [Multi-domain] Cd Length: 318 Bit Score: 157.54 E-value: 6.59e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 3 GIKSIASYVPADGIDNyAQGAKFAK-DEEFIIGKIGsaFLPRKEAGQE--TSDLCVEAV-NALfaNNPQLKRESIDaLIV 78
Cdd:TIGR00747 4 GILGTGSYLPEKVLTN-ADLEKMVDtSDEWIVTRTG--IKERRIAADDetSSTMGFEAAkRAI--ENAGISKDDID-LII 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 79 VTQNGDEEGLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTML 158
Cdd:TIGR00747 78 VATTTPDHAFPSAACMVQAYLGI-KGIPAFDLSAACAGFIYALSVAKQYIESGKYKTVLVVGAEKLSSTLDWTDRGTCVL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 159 FGDAATATWMGE-DASWLLGKAKFGTDGSGAPHLKVSDGV---------FFMNGRQVFNFALLKVPAHLHALLDESDLKA 228
Cdd:TIGR00747 157 FGDGAGAVVLGEsEDPGGIISTHLGADGTQGEALYLPAGGrptsgpspfITMEGNEVFKHAVRKMGDVVEETLEANGLDP 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 229 DDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPL----LLEKHALDSTwKRVAISGFGVGLSWGSA 304
Cdd:TIGR00747 237 EDIDWFVPHQANLRIIEALAKRLE-LDMSQVVKTVHKYGNTSAASIPLaldeLLRTGRIKPG-DLLLLVAFGGGLTWGAA 314
|
...
gi 516456528 305 ILY 307
Cdd:TIGR00747 315 LVR 317
|
|
| PLN02326 |
PLN02326 |
3-oxoacyl-[acyl-carrier-protein] synthase III |
67-306 |
1.26e-43 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III
Pssm-ID: 215185 Cd Length: 379 Bit Score: 153.35 E-value: 1.26e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 67 QLKRESIDALIVVTQNGDEegLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSK 146
Cdd:PLN02326 112 GVDPEDVDLVLLCTSSPDD--LFGSAPQVQAALGC-TNALAFDLTAACSGFVLGLVTAARFIRGGGYKNVLVIGADALSR 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 147 IVDPEDRNTTMLFGDAATATWM---GEDASWLLGKAkFGTDGSGAPHLKV--------------SDGVFF---------- 199
Cdd:PLN02326 189 YVDWTDRGTCILFGDGAGAVVLqacDDDEDGLLGFD-MHSDGNGHKHLHAtfkgedddssggntNGVGDFppkkasysci 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 200 -MNGRQVFNFALLKVPAHLHALLDESDLKADDIDAFCIHQGSAAIVDAVARRFeDAPVDKFIKDMVETGNTVSSSIPLLL 278
Cdd:PLN02326 268 qMNGKEVFKFAVRCVPQVIESALQKAGLTAESIDWLLLHQANQRIIDAVAQRL-GIPPEKVISNLANYGNTSAASIPLAL 346
|
250 260 270
....*....|....*....|....*....|.
gi 516456528 279 EKHALDSTWKR---VAISGFGVGLSWGSAIL 306
Cdd:PLN02326 347 DEAVRSGKVKKgdvIATAGFGAGLTWGSAIV 377
|
|
| fabH |
CHL00203 |
3-oxoacyl-acyl-carrier-protein synthase 3; Provisional |
4-306 |
3.86e-43 |
|
3-oxoacyl-acyl-carrier-protein synthase 3; Provisional
Pssm-ID: 164577 [Multi-domain] Cd Length: 326 Bit Score: 150.87 E-value: 3.86e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 4 IKSIASYVPADGIDNYAQGAKFAKDEEFIIGKIGsaFLPRKEAGQETS--DLCVEAVN-ALFANNpqLKRESIDALIVVT 80
Cdd:CHL00203 5 ILSTGSSVPNFSVENQQFEDIIETSDHWISTRTG--IKKRHLAPSSTSltKLAAEAANkALDKAH--MDPLEIDLIILAT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 81 QNGDEegLPHTAAIVQDKLGLPTHVAaFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTMLFG 160
Cdd:CHL00203 81 STPDD--LFGSASQLQAEIGATRAVA-FDITAACSGFILALVTATQFIQNGSYKNILVVGADTLSKWIDWSDRKTCILFG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 161 DAATATWMGEDASWLLGKAKFGTDGSGAPHL---------------KVSDGVF---FMNGRQVFNFALLKVPAHLHALLD 222
Cdd:CHL00203 158 DGAGAAIIGASYENSILGFKLCTDGKLNSHLqlmnkpvnnqsfgttKLPQGQYqsiSMNGKEVYKFAVFQVPAVIIKCLN 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 223 ESDLKADDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPLllekhALDSTWKR--------VAISG 294
Cdd:CHL00203 238 ALNISIDEVDWFILHQANKRILEAIANRLS-VPNSKMITNLEKYGNTSAASIPL-----ALDEAIQNnkiqpgqiIVLSG 311
|
330
....*....|..
gi 516456528 295 FGVGLSWGSAIL 306
Cdd:CHL00203 312 FGAGLTWGAIVL 323
|
|
| PRK12880 |
PRK12880 |
beta-ketoacyl-ACP synthase III; |
51-306 |
4.10e-35 |
|
beta-ketoacyl-ACP synthase III;
Pssm-ID: 171793 Cd Length: 353 Bit Score: 130.09 E-value: 4.10e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 51 SDLCVEAVNALFaNNPQLKRESIDALIVVTQNGDEeGLPHTAAIVQDKLGLPTHVAAFDLSLGCSGYVYGIYAMKGFMEa 130
Cdd:PRK12880 61 SDLGKHAANTLL-QGLNIDKNSLDALIVVTQSPDF-FMPSTACYLHQLLNLSSKTIAFDLGQACAGYLYGLFVAHSLIQ- 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 131 TGLKNGLLITADPYSKIVDPEDRNTTMLFGDAATATwmgedaswLLGKAKF-------GTDGSGAPHLKVSDGVF----- 198
Cdd:PRK12880 138 SGLGKILLICGDTLSKFIHPKNMNLAPIFGDGVSAT--------LIEKTDFneaffelGSDGKYFDKLIIPKGAMripka 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 199 --------------------FMNGRQVFNFALLKVPAHLHALLDESDLKADDIDAFCIHQGSAAIVDAVAR--RFEDAPV 256
Cdd:PRK12880 210 difnddslmqteefrqlenlYMDGANIFNMALECEPKSFKEILEFSKVDEKDIAFHLFHQSNAYLVDCIKEelKLNDDKV 289
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 516456528 257 DKFIkdMVETGNTVSSSIPLLLEKHALDSTWKrVAISGFGVGLSWGSAIL 306
Cdd:PRK12880 290 PNFI--MEKYANLSACSLPALLCELDTPKEFK-ASLSAFGAGLSWGSAVL 336
|
|
| PRK05963 |
PRK05963 |
beta-ketoacyl-ACP synthase III; |
10-306 |
2.32e-29 |
|
beta-ketoacyl-ACP synthase III;
Pssm-ID: 180328 [Multi-domain] Cd Length: 326 Bit Score: 114.05 E-value: 2.32e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 10 YVPADGIDNYAQGAKFAKDEEFIIGKIGSAFLPRKEAGQETSDLCVEAVNALFANnPQLKRESIDALIVVTQNGDEEgLP 89
Cdd:PRK05963 12 AVPDRRVENAEIEAQLGLETGWIERRTGIRCRRWAAPDETLSDLAASAGDMALSD-AGIERSDIALTLLATSTPDHL-LP 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 90 HTAAIVQDKLGLPtHVAAFDLSLGCSGYVYGIYAMKGFMEATGlKNGLLITADPYSKIVDPEDRNTTMLFGDAATATWMG 169
Cdd:PRK05963 90 PSAPLLAHRLGLQ-NSGAIDLAGACAGFLYALVLADGFVRAQG-KPVLVVAANILSRRINMAERASAVLFADAAGAVVLA 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 170 ---EDASWLLGkAKFGTDGSG---------------APHLKVSDGVFFM-NGRQVFNFALLKVPAHLHALLDESDLKADD 230
Cdd:PRK05963 168 psaKANSGVLG-SQLISDGSHydlikipaggsarpfAPERDASEFLMTMqDGRAVFTEAVRMMSGASQNVLASAAMTPQD 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 231 IDAFCIHQGSAAIVDAVARRFEDAPvDKFIKDMVETGNTVSSSIPLLL----EKHALDSTwKRVAISGFGVGLSWGSAIL 306
Cdd:PRK05963 247 IDRFFPHQANARIVDKVCETIGIPR-AKAASTLETYGNSSAATIPLSLslanLEQPLREG-ERLLFAAAGAGMTGGAVVM 324
|
|
| ACP_syn_III_C |
pfam08541 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ... |
221-306 |
1.38e-24 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430060 Cd Length: 90 Bit Score: 94.88 E-value: 1.38e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 221 LDESDLKADDIDAFCIHQGSAAIVDAVARRFEdAPVDKFIKDMVETGNTVSSSIPLLLEkHALDS----TWKRVAISGFG 296
Cdd:pfam08541 1 LEKAGLTPEDIDWFVPHQANLRIIDAVAKRLG-LPPEKVVVNLDEYGNTSAASIPLALD-EAVEEgklkPGDLVLLVGFG 78
|
90
....*....|
gi 516456528 297 VGLSWGSAIL 306
Cdd:pfam08541 79 AGLTWGAALL 88
|
|
| ACP_syn_III |
pfam08545 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl- ... |
108-185 |
2.62e-22 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.180, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430064 [Multi-domain] Cd Length: 80 Bit Score: 88.34 E-value: 2.62e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 108 FDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTMLFGDAATATWMG--EDASWLLGKAKFGTDG 185
Cdd:pfam08545 1 FDINAACSGFVYALSTAAALIRSGRAKNVLVIGAETLSKILDWTDRSTAVLFGDGAGAVVLEatDEPGARILDSVLGSDG 80
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
1-306 |
9.80e-20 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 87.49 E-value: 9.80e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 1 MIGIKSIASYVPADGIDN--YAQGAKFAKDEEFIigKIGSaflpRKEAGQETS--DLCVEAVNALFANNpQLKRESIDAL 76
Cdd:cd00827 1 DVGIEAIGAYLPRYRVDNeeLAEGLGVDPGKYTT--GIGQ----RHMAGDDEDvpTMAVEAARRALERA-GIDPDDIGLL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 77 IVVTQNGDEEGLPHtAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTT 156
Cdd:cd00827 74 IVATESPIDKGKSA-ATYLAELLGL-TNAEAFDLKQACYGGTAALQLAANLVESGPWRYALVVASDIASYLLDEGSALEP 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 157 MlFGDAATA---------TWMGEDASWLLGKAKFGTDGSGAPHLKVSDGVFF---------MNGRQVFNFALLKVPAHLH 218
Cdd:cd00827 152 T-LGDGAAAmlvsrnpgiLAAGIVSTHSTSDPGYDFSPYPVMDGGYPKPCKLayairltaePAGRAVFEAAHKLIAKVVR 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 219 ALLDESDLKaDDIDAFCIHQGSAAIVDAVARRFEDAPVDKFIKDMV----ETGNTVSSSIPLLLEkHALDS----TWKRV 290
Cdd:cd00827 231 KALDRAGLS-EDIDYFVPHQPNGKKILEAVAKKLGGPPEKASQTRWillrRVGNMYAASILLGLA-SLLESgklkAGDRV 308
|
330
....*....|....*.
gi 516456528 291 AISGFGVGLSWGSAIL 306
Cdd:cd00827 309 LLFSYGSGFTAEAFVL 324
|
|
| PRK07204 |
PRK07204 |
beta-ketoacyl-ACP synthase III; |
2-306 |
1.18e-19 |
|
beta-ketoacyl-ACP synthase III;
Pssm-ID: 235964 Cd Length: 329 Bit Score: 87.58 E-value: 1.18e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 2 IGIKSIASYVPADGIDNYAQGAKFAKDEEFIIGKigSAFLPRKEAGQETSDLcVEAVNALFA-NNPQLKRESIDALIVVT 80
Cdd:PRK07204 5 ISIKGIGTYLPKRKVDSLELDKKLDLPEGWVLKK--SGVKTRHFVDGETSSY-MGAEAAKKAvEDAKLTLDDIDCIICAS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 81 QNGdEEGLPHTAAIVQDKLGLP-THVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKIVDPEDRNTTMLF 159
Cdd:PRK07204 82 GTI-QQAIPCTASLIQEQLGLQhSGIPCFDINSTCLSFITALDTISYAIECGRYKRVLIISSEISSVGLNWGQNESCILF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 160 GDAATATWM--GEDASWLLGkAKFGTDGSGAPHLKV-----------------SDGVFFMNGRQVFNFALLKVPAHLHAL 220
Cdd:PRK07204 161 GDGAAAVVItkGDHSSRILA-SHMETYSSGAHLSEIrgggtmihpreyseerkEDFLFDMNGRAIFKLSSKYLMKFIDKL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 221 LDESDLKADDIDAFCIHQGSAAIVDAVARRFeDAPVDKFIKDMVETGNTVSSSIPLLLEkHALDST----WKRVAISGFG 296
Cdd:PRK07204 240 LMDAGYTLADIDLIVPHQASGPAMRLIRKKL-GVDEERFVTIFEDHGNMIAASIPVALF-EAIKQKkvqrGNKILLLGTS 317
|
330
....*....|
gi 516456528 297 VGLSWGSAIL 306
Cdd:PRK07204 318 AGLSIGGILL 327
|
|
| PRK07515 |
PRK07515 |
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed |
68-306 |
4.99e-15 |
|
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
Pssm-ID: 236037 Cd Length: 372 Bit Score: 74.53 E-value: 4.99e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 68 LKRESIDALIVVTQNgDEEGLPHTAAIVQDKLGlpTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADPYSKI 147
Cdd:PRK07515 112 RTAEDIDAVIVACSN-MQRAYPAMAIEIQQALG--IEGFAFDMNVACSSATFGIQTAANAIRSGSARRVLVVNPEICSGH 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 148 VDPEDRNTTMLFGDAATATWMGEDA------SW-LLG-----------KAKFG----TDGSGAPhlkVSDGVFFMNGRQV 205
Cdd:PRK07515 189 LNFRDRDSHFIFGDVATAVIVERADtatsagGFeILGtrlftqfsnniRNNFGflnrADPEGIG---ARDKLFVQEGRKV 265
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 206 FNFALLKVPAHLHALLDESDLKADDIDAFCIHQGSAAIVDAVARRF-------EDAPVdkfIKDmvETGNTVSSSIPLLL 278
Cdd:PRK07515 266 FKEVCPMVAEHIVEHLAENGLTPADVKRFWLHQANINMNQLIGKKVlgrdatpEEAPV---ILD--EYANTSSAGSIIAF 340
|
250 260
....*....|....*....|....*....
gi 516456528 279 EKHALDSTWKRVA-ISGFGVGLSWGSAIL 306
Cdd:PRK07515 341 HKHSDDLAAGDLGvICSFGAGYSIGSVIV 369
|
|
| CHS_like |
cd00831 |
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, ... |
49-300 |
5.30e-14 |
|
Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.
Pssm-ID: 238427 [Multi-domain] Cd Length: 361 Bit Score: 71.49 E-value: 5.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 49 ETSDLCVEAVNALFANNPQLKREsIDALIVVTQNG-DEEGLphTAAIVQdKLGLPTHVAAFDLS-LGCSGYVYGIYAMKG 126
Cdd:cd00831 84 EARELAEEAARGALDEAGLRPSD-IDHLVVNTSTGnPTPSL--DAMLIN-RLGLRPDVKRYNLGgMGCSAGAIALDLAKD 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 127 FMEATGLKNGLLITADPYSKIVDPEDRNTTM----LFGDAATATWMGEDASWLLGKAKFG----------TDGSGAPHLK 192
Cdd:cd00831 160 LLEANPGARVLVVSTELCSLWYRGPDHRSMLvgnaLFGDGAAAVLLSNDPRDRRRERPLFelvraastllPDSEDAMGWH 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 193 VSDGVFFMN-GRQVFNFALLKVPAHLHALLDE--SDLKADDIDAFCIHQGSAAIVDAVARRFEDAPVDKFIKDMV--ETG 267
Cdd:cd00831 240 LGEEGLTFVlSRDVPRLVEKNLERVLRKLLARlgIGLFKLAFDHWCVHPGGRAVLDAVEKALGLSPEDLEASRMVlrRYG 319
|
250 260 270
....*....|....*....|....*....|....*.
gi 516456528 268 NTVSSSIPLLLEKHALDSTWK---RVAISGFGVGLS 300
Cdd:cd00831 320 NMSSSSVLYVLAYMEAKGRVKrgdRGLLIAFGPGFT 355
|
|
| PksG |
COG3425 |
3-hydroxy-3-methylglutaryl CoA synthase [Lipid transport and metabolism]; ... |
1-298 |
1.12e-10 |
|
3-hydroxy-3-methylglutaryl CoA synthase [Lipid transport and metabolism]; 3-hydroxy-3-methylglutaryl CoA synthase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 442651 [Multi-domain] Cd Length: 382 Bit Score: 61.73 E-value: 1.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 1 MIGIKSIASYVP-----------ADGIDNyaqgAKFAKDeefiIGKIGSAFLPrkeAGQETSDLCVEAVNALFANNpQLK 69
Cdd:COG3425 2 KVGIDAIGFYIPryrldleelaeARGVDP----EKYTKG----LGQEEKSVPP---PDEDAVTMAANAARRALDRA-GID 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 70 RESIDALIVVTQNGDEEGLPhTAAIVQDKLGLPTHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLLITADpYSKIvd 149
Cdd:COG3425 70 PSDIGAVYVGTESGPDASKP-IATYVHGALGLPPNCRAFELKFACYAGTAALQAALGWVASGPNKKALVIASD-IARY-- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 150 peDRNTT--MLFGDAATATWMGED---ASWLLGKAKFGTDgsgaphlkVSDgvFFM-NGRQvfnFAL----LKVPAHLHA 219
Cdd:COG3425 146 --GPGSAgeYTQGAGAVAMLVGADpriAEIEGGSGSYTTD--------VMD--FWRpNGSD---YPLvdgrFSEPAYLDH 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 220 L-------LDESDLKADDIDAFCIHQGSAAIVDAVAR---RFEDAPVDKFIKDMVET--------GNTVSSSIPL----L 277
Cdd:COG3425 211 LeeavkdyKEKTGLKPDDFDYFVFHQPFGKMPKKAAKklgRKAGREIQEDFEEQVEPsliysrriGNTYTGSLYLglasL 290
|
330 340
....*....|....*....|.
gi 516456528 278 LEkHALDSTWKRVAISGFGVG 298
Cdd:COG3425 291 LD-NAKDLPGDRIGLFSYGSG 310
|
|
| PRK09258 |
PRK09258 |
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed |
45-299 |
1.71e-09 |
|
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
Pssm-ID: 181732 Cd Length: 338 Bit Score: 57.97 E-value: 1.71e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 45 EAGQETSDLCVEAVNALFANNpQLKRESIDALI--VVTQNGDEeglPHTAAIVQDKLGLPTHVAAFDLSLGCSGYVYGIY 122
Cdd:PRK09258 56 PEGTQLSDGAIAAGRKALAEA-GIDPSDIGLLIntSVCRDYLE---PATACRVHHNLGLPKSCANFDVSNACLGFLNGML 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 123 AMKGFMEATGLKNGLLITADPYSKIVDP------EDRNTTMLFGDA-ATATWMGEDASWLLGKAKFGTDGS---GAPHLK 192
Cdd:PRK09258 132 DAANMIELGQIDYALVVSGESAREIVEAtidrllAPETTREDFAQSfATLTLGSGAAAAVLTRGSLHPRGHrllGGVTRA 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 193 VSD-------GVFFM--NGRQVFNFALLKVPAHLHALLDESDLKADDIDAFCIHQGSAAIVDAVARRFEDAPVdkfiKDM 263
Cdd:PRK09258 212 ATEhhelcqgGRDGMrtDAVGLLKEGVELAVDTWEAFLAQLGWAVEQVDRVICHQVGAAHTRAILKALGIDPE----KVF 287
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 516456528 264 V---ETGNTVSSSIPLLL----EKHALdSTWKRVAISGFGVGL 299
Cdd:PRK09258 288 TtfpTLGNMGPASLPITLamaaEEGFL-KPGDRVALLGIGSGL 329
|
|
| PRK06840 |
PRK06840 |
3-oxoacyl-ACP synthase; |
1-186 |
7.97e-08 |
|
3-oxoacyl-ACP synthase;
Pssm-ID: 235872 Cd Length: 339 Bit Score: 53.09 E-value: 7.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 1 MIGIKSIASYVPadgiDNYAQGAKFAKD----EEFIIGKIGSAFLPRKEAGQETSDLCVEAVNALFANnPQLKRESIDAL 76
Cdd:PRK06840 4 NVGIVGTGVYLP----KDVMTAEEIAEKtgipEEVVIEKFGIYEKPVPGPEDHTSDMAIAAAKPALKQ-AGVDPAAIDVV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 77 IVVTQNGDEEGLPHTAAIVQDKLGLpTHVAAFDLSLGCSGYVYGIYAMKGFMEATG-LKNGLLITADPYSKIVDPEDRNT 155
Cdd:PRK06840 79 IYIGSEHKDYPVWSSAPKIQHEIGA-KNAWAFDIMAVCASFPIALKVAKDLLYSDPsIENVLLVGGYRNSDLVDYDNPRT 157
|
170 180 190
....*....|....*....|....*....|....*
gi 516456528 156 TMLF--GDAATATWMGEDA--SWLLGKAkFGTDGS 186
Cdd:PRK06840 158 RFMFnfAAGGSAALLKKDAgkNRILGSA-IITDGS 191
|
|
| decarbox_cond_enzymes |
cd00825 |
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new ... |
89-306 |
3.96e-05 |
|
decarboxylating condensing enzymes; Family of enzymes that catalyze the formation of a new carbon-carbon bond by a decarboxylating Claisen-like condensation reaction. Members are involved in the synthesis of fatty acids and polyketides, a diverse group of natural products. Both pathways are an iterative series of additions of small carbon units, usually acetate, to a nascent acyl group. There are 2 classes of decarboxylating condensing enzymes, which can be distinguished by sequence similarity, type of active site residues and type of primer units (acetyl CoA or acyl carrier protein (ACP) linked units).
Pssm-ID: 238421 [Multi-domain] Cd Length: 332 Bit Score: 44.55 E-value: 3.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 89 PHTAAIVQDKLGLptHVAAFDLSLGCSGYVYGIYAMKGFMEATGLKNGLL----ITADPYSKIVDP-------------- 150
Cdd:cd00825 73 PGASGQIATPLGI--HGPAYDVSAACAGSLHALSLAADAVQNGKQDIVLAggseELAAPMDCEFDAmgalstpekasrtf 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 151 EDRNTTMLFGDAATATWMGEDASWLLGKA--KFGTDGSGAPHLKVSDGVFFMNGRQVfnfallkVPAHLHALlDESDLKA 228
Cdd:cd00825 151 DAAADGFVFGDGAGALVVEELEHALARGAhiYAEIVGTAATIDGAGMGAFAPSAEGL-------ARAAKEAL-AVAGLTV 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516456528 229 DDIDAFCIHQGSAAIVDAVARRF---EDAPVDKFIK-DMVETGNTVSSSIPLLLEK--------------------HALD 284
Cdd:cd00825 223 WDIDYLVAHGTGTPIGDVKELKLlrsEFGDKSPAVSaTKAMTGNLSSAAVVLAVDEavlmlehgfippsihieeldEAGL 302
|
250 260 270
....*....|....*....|....*....|
gi 516456528 285 STWKR--------VAISGFGVGLSWGSAIL 306
Cdd:cd00825 303 NIVTEttprelrtALLNGFGLGGTNATLVL 332
|
|
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