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Conserved domains on  [gi|516458286|ref|WP_017847126|]
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MULTISPECIES: Holliday junction branch migration protein RuvA [Pseudomonas]

Protein Classification

Holliday junction ATP-dependent DNA helicase RuvA( domain architecture ID 11478104)

Holliday junction ATP-dependent DNA helicase RuvA is involved in branch migration of heteroduplex DNA in homologous recombination by stimulating the ATPase activity of RuvB

CATH:  1.10.150.20
EC:  3.6.4.12
Gene Ontology:  GO:0009378|GO:0003677|GO:0016887|GO:0005524|GO:0006281|GO:0006310
SCOP:  4000746|4001893|4001026

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ruvA PRK00116
Holliday junction branch migration protein RuvA;
1-202 1.03e-104

Holliday junction branch migration protein RuvA;


:

Pssm-ID: 234645 [Multi-domain]  Cd Length: 192  Bit Score: 299.36  E-value: 1.03e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFIGKRDRDFFRELIRLNG 80
Cdd:PRK00116   1 MIGYLKGKLVEKGPDYVVIEVNGVGYEVQVPMRTLYELPEVGEEVKLYTHLVVREDAILLYGFLTKEERELFRLLISVSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286  81 VGPKLALALMSSLEVDELVRAVSAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEVVPSmfalvpnqpnqPAAQVASAE 160
Cdd:PRK00116  81 VGPKLALAILSGLSPEELVQAIANGDVKALTKVPGIGKKTAERIVLELKDKLAAAASAAA-----------AAAAASSAL 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 516458286 161 SDAVSALISLGYKPQEASKAVSAIKDKNLSSEDMIRRALKGM 202
Cdd:PRK00116 150 EEAVSALVALGYKPKEASKAVAKILKEAASVEELIREALKLL 191
 
Name Accession Description Interval E-value
ruvA PRK00116
Holliday junction branch migration protein RuvA;
1-202 1.03e-104

Holliday junction branch migration protein RuvA;


Pssm-ID: 234645 [Multi-domain]  Cd Length: 192  Bit Score: 299.36  E-value: 1.03e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFIGKRDRDFFRELIRLNG 80
Cdd:PRK00116   1 MIGYLKGKLVEKGPDYVVIEVNGVGYEVQVPMRTLYELPEVGEEVKLYTHLVVREDAILLYGFLTKEERELFRLLISVSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286  81 VGPKLALALMSSLEVDELVRAVSAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEVVPSmfalvpnqpnqPAAQVASAE 160
Cdd:PRK00116  81 VGPKLALAILSGLSPEELVQAIANGDVKALTKVPGIGKKTAERIVLELKDKLAAAASAAA-----------AAAAASSAL 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 516458286 161 SDAVSALISLGYKPQEASKAVSAIKDKNLSSEDMIRRALKGM 202
Cdd:PRK00116 150 EEAVSALVALGYKPKEASKAVAKILKEAASVEELIREALKLL 191
RuvA COG0632
Holliday junction resolvasome RuvABC DNA-binding subunit [Replication, recombination and ...
 1-200 1.29e-100

Holliday junction resolvasome RuvABC DNA-binding subunit [Replication, recombination and repair];


Pssm-ID: 440397 [Multi-domain]  Cd Length: 195  Bit Score: 288.96  E-value: 1.29e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFIGKRDRDFFRELIRLNG 80
Cdd:COG0632    1 MIAYLRGTLVEKGPDYVVIDVGGVGYEVFVPLSTLSALPEVGEEVKLYTHLVVREDALTLYGFATEEERELFRLLISVSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286  81 VGPKLALALMSSLEVDELVRAVSAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEVVPSmfalvpnQPNQPAAQVASAE 160
Cdd:COG0632   81 VGPKLALAILSGLSPEELARAIASGDVKALTKVPGIGKKTAERIILELKDKLGKLALAAG-------AAAAAAAAASSAL 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 516458286 161 SDAVSALISLGYKPQEASKAVSAI--KDKNLSSEDMIRRALK 200
Cdd:COG0632  154 EEAVSALVALGYSPKEAEKAVAKVlkEGPDASVEELIRAALK 195
ruvA TIGR00084
Holliday junction DNA helicase, RuvA subunit; RuvA specifically binds Holliday junctions as a ...
 1-203 1.59e-65

Holliday junction DNA helicase, RuvA subunit; RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129193 [Multi-domain]  Cd Length: 191  Bit Score: 199.91  E-value: 1.59e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286    1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSvGEPLTLHTHLVVREDAQLLYGFIGKRDRDFFRELIRLNG 80
Cdd:TIGR00084   1 MIGFLFGKVIEVSKPKIIIEVNGVGYELQVPMTCAYELNL-EQKAQVFTHLVVREDAELLFGFNTLEERELFKELIKVNG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   81 VGPKLALALMSSLEVDELVRAVSAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEvvpsmfalvPNQPNQPAaqvASAE 160
Cdd:TIGR00084  80 VGPKLALAILSNMSPEEFVYAIETEEVKALVKIPGVGKKTAERLLLELKGKLKGNK---------NLEMFTPT---EAAR 147

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 516458286  161 SDAVSALISLGYKPQEASKAVSAIKDK-NLSSEDMIRRALKGMI 203
Cdd:TIGR00084 148 DELFEALVSLGYKPQEIQQALKKIKNKpDFAIEQDIEEALKQLL 191
RuvA_N pfam01330
RuvA N terminal domain; The N terminal domain of RuvA has an OB-fold structure. This domain ...
 1-62 1.12e-30

RuvA N terminal domain; The N terminal domain of RuvA has an OB-fold structure. This domain forms the RuvA tetramer contacts.


Pssm-ID: 460162 [Multi-domain]  Cd Length: 61  Bit Score: 106.74  E-value: 1.12e-30
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516458286    1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPsVGEPLTLHTHLVVREDAQLLYG 62
Cdd:pfam01330   1 MIAYLKGTVVEKGPDYVVIDVGGVGYEVFISLSTLSKLA-VGEEVKLYTHLVVREDALTLYG 61
UBA_RuvA_C cd14332
C-terminal UBA-like domain of holliday junction ATP-dependent DNA helicase RuvA; RuvA, along ...
 158-200 1.86e-11

C-terminal UBA-like domain of holliday junction ATP-dependent DNA helicase RuvA; RuvA, along with RuvB and RuvC proteins, is involved in branch migration of heteroduplex DNA in homologous recombination that is a crucial process for maintaining genomic integrity and generating biological diversity in all living organisms. RuvA has a tetrameric architecture in which each subunit comprised of three distinct domains. This model corresponds to the C-terminal domain of RuvA which is distantly related to the ubiquitin-associated (UBA) domain. It plays a significant role in the ATP-dependent branch migration of the hetero-duplex through direct contact with RuvB. Within the Holliday junction, the C-terminal domain makes no interaction with DNA.


Pssm-ID: 270517 [Multi-domain]  Cd Length: 45  Bit Score: 56.69  E-value: 1.86e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 516458286 158 SAESDAVSALISLGYKPQEASKAVSAIKDK--NLSSEDMIRRALK 200
Cdd:cd14332    1 PVLEDAVSALVALGYSRKEAEKAVKKVLAEapGLSVEELIREALK 45
 
Name Accession Description Interval E-value
ruvA PRK00116
Holliday junction branch migration protein RuvA;
1-202 1.03e-104

Holliday junction branch migration protein RuvA;


Pssm-ID: 234645 [Multi-domain]  Cd Length: 192  Bit Score: 299.36  E-value: 1.03e-104
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFIGKRDRDFFRELIRLNG 80
Cdd:PRK00116   1 MIGYLKGKLVEKGPDYVVIEVNGVGYEVQVPMRTLYELPEVGEEVKLYTHLVVREDAILLYGFLTKEERELFRLLISVSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286  81 VGPKLALALMSSLEVDELVRAVSAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEVVPSmfalvpnqpnqPAAQVASAE 160
Cdd:PRK00116  81 VGPKLALAILSGLSPEELVQAIANGDVKALTKVPGIGKKTAERIVLELKDKLAAAASAAA-----------AAAAASSAL 149

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 516458286 161 SDAVSALISLGYKPQEASKAVSAIKDKNLSSEDMIRRALKGM 202
Cdd:PRK00116 150 EEAVSALVALGYKPKEASKAVAKILKEAASVEELIREALKLL 191
RuvA COG0632
Holliday junction resolvasome RuvABC DNA-binding subunit [Replication, recombination and ...
 1-200 1.29e-100

Holliday junction resolvasome RuvABC DNA-binding subunit [Replication, recombination and repair];


Pssm-ID: 440397 [Multi-domain]  Cd Length: 195  Bit Score: 288.96  E-value: 1.29e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFIGKRDRDFFRELIRLNG 80
Cdd:COG0632    1 MIAYLRGTLVEKGPDYVVIDVGGVGYEVFVPLSTLSALPEVGEEVKLYTHLVVREDALTLYGFATEEERELFRLLISVSG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286  81 VGPKLALALMSSLEVDELVRAVSAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEVVPSmfalvpnQPNQPAAQVASAE 160
Cdd:COG0632   81 VGPKLALAILSGLSPEELARAIASGDVKALTKVPGIGKKTAERIILELKDKLGKLALAAG-------AAAAAAAAASSAL 153

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 516458286 161 SDAVSALISLGYKPQEASKAVSAI--KDKNLSSEDMIRRALK 200
Cdd:COG0632  154 EEAVSALVALGYSPKEAEKAVAKVlkEGPDASVEELIRAALK 195
ruvA TIGR00084
Holliday junction DNA helicase, RuvA subunit; RuvA specifically binds Holliday junctions as a ...
 1-203 1.59e-65

Holliday junction DNA helicase, RuvA subunit; RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129193 [Multi-domain]  Cd Length: 191  Bit Score: 199.91  E-value: 1.59e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286    1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPSvGEPLTLHTHLVVREDAQLLYGFIGKRDRDFFRELIRLNG 80
Cdd:TIGR00084   1 MIGFLFGKVIEVSKPKIIIEVNGVGYELQVPMTCAYELNL-EQKAQVFTHLVVREDAELLFGFNTLEERELFKELIKVNG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   81 VGPKLALALMSSLEVDELVRAVSAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEvvpsmfalvPNQPNQPAaqvASAE 160
Cdd:TIGR00084  80 VGPKLALAILSNMSPEEFVYAIETEEVKALVKIPGVGKKTAERLLLELKGKLKGNK---------NLEMFTPT---EAAR 147

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 516458286  161 SDAVSALISLGYKPQEASKAVSAIKDK-NLSSEDMIRRALKGMI 203
Cdd:TIGR00084 148 DELFEALVSLGYKPQEIQQALKKIKNKpDFAIEQDIEEALKQLL 191
ruvA PRK14600
Holliday junction branch migration protein RuvA;
1-200 2.49e-31

Holliday junction branch migration protein RuvA;


Pssm-ID: 173064 [Multi-domain]  Cd Length: 186  Bit Score: 112.53  E-value: 2.49e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286   1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLpSVGEPLTLHTHLVV-REDAQLLYGFIGKRDRDFFRELIRLN 79
Cdd:PRK14600   1 MIGSLSGIVEEVRSDYIILNVGNVGYIVYLSAKVLSTC-KIGDNIKLYIETYVnRDNVTQLYGFLNREEQDCLRMLVKVS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516458286  80 GVGPKLALALMSSLEVDELVRAVSAQDTSALtKVPGVGKKTAERLLVELKDRFKAWEVVPSMFALVpnqpnqpaaqvasa 159
Cdd:PRK14600  80 GVNYKTAMSILSKLTPEQLFSAIVNEDKAAL-KVNGIGEKLINRIITELQYKVSKLEINETNFIII-------------- 144

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 516458286 160 ESDAVSALISLGYkpqEASKAVSAIKD--KNLSSEDMIRRALK 200
Cdd:PRK14600 145 NDDALAALISLGY---EKTKAFNAIQKikPNLSTQDIIRKALK 184
RuvA_N pfam01330
RuvA N terminal domain; The N terminal domain of RuvA has an OB-fold structure. This domain ...
 1-62 1.12e-30

RuvA N terminal domain; The N terminal domain of RuvA has an OB-fold structure. This domain forms the RuvA tetramer contacts.


Pssm-ID: 460162 [Multi-domain]  Cd Length: 61  Bit Score: 106.74  E-value: 1.12e-30
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516458286    1 MIGRLRGTLAEKQPPHLILDVNGLGYELEVPMTTLYRLPsVGEPLTLHTHLVVREDAQLLYG 62
Cdd:pfam01330   1 MIAYLKGTVVEKGPDYVVIDVGGVGYEVFISLSTLSKLA-VGEEVKLYTHLVVREDALTLYG 61
HHH_5 pfam14520
Helix-hairpin-helix domain;
72-130 4.65e-14

Helix-hairpin-helix domain;


Pssm-ID: 434010 [Multi-domain]  Cd Length: 57  Bit Score: 63.66  E-value: 4.65e-14
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516458286   72 FRELIRLNGVGPKLALALMSSL--EVDELVRAvsaqDTSALTKVPGVGKKTAERLLVELKD 130
Cdd:pfam14520   1 FEELLSISGIGPKTALALLSAGigTVEDLAEA----DVDELAEIPGIGEKTAQRIILELRD 57
RuvA_C pfam07499
RuvA, C-terminal domain; Homologous recombination is a crucial process in all living organizms. ...
 158-202 6.98e-12

RuvA, C-terminal domain; Homologous recombination is a crucial process in all living organizms. In bacteria, this process the RuvA, RuvB, and RuvC proteins are involved. More specifically the proteins process the Holliday junction DNA. RuvA is comprised of three distinct domains. The domain represents the C-terminal domain and plays a significant role in the ATP-dependent branch migration of the hetero-duplex through direct contact with RuvB. Within the Holliday junction, the C-terminal domain makes no interaction with DNA.


Pssm-ID: 462183 [Multi-domain]  Cd Length: 47  Bit Score: 57.87  E-value: 6.98e-12
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 516458286  158 SAESDAVSALISLGYKPQEASKAVSAI-KDKNLSSEDMIRRALKGM 202
Cdd:pfam07499   1 DALEDAVSALVALGYKEKEAEKAVSKVlANPGLSVEELIRAALKLL 46
UBA_RuvA_C cd14332
C-terminal UBA-like domain of holliday junction ATP-dependent DNA helicase RuvA; RuvA, along ...
 158-200 1.86e-11

C-terminal UBA-like domain of holliday junction ATP-dependent DNA helicase RuvA; RuvA, along with RuvB and RuvC proteins, is involved in branch migration of heteroduplex DNA in homologous recombination that is a crucial process for maintaining genomic integrity and generating biological diversity in all living organisms. RuvA has a tetrameric architecture in which each subunit comprised of three distinct domains. This model corresponds to the C-terminal domain of RuvA which is distantly related to the ubiquitin-associated (UBA) domain. It plays a significant role in the ATP-dependent branch migration of the hetero-duplex through direct contact with RuvB. Within the Holliday junction, the C-terminal domain makes no interaction with DNA.


Pssm-ID: 270517 [Multi-domain]  Cd Length: 45  Bit Score: 56.69  E-value: 1.86e-11
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 516458286 158 SAESDAVSALISLGYKPQEASKAVSAIKDK--NLSSEDMIRRALK 200
Cdd:cd14332    1 PVLEDAVSALVALGYSRKEAEKAVKKVLAEapGLSVEELIREALK 45
MUS81 COG1948
ERCC4-type crossover junction endonuclease [Replication, recombination and repair];
78-123 2.74e-04

ERCC4-type crossover junction endonuclease [Replication, recombination and repair];


Pssm-ID: 441551 [Multi-domain]  Cd Length: 214  Bit Score: 40.16  E-value: 2.74e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 516458286  78 LNGVGPKLALALmssLEVDELVRAVSAQDTSALTKVPGVGKKTAER 123
Cdd:COG1948  160 LPGIGPKLARRL---LEHFGSVEAVFNASEEELMKVEGIGEKTAER 202
ComEA COG1555
DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair]; ...
 74-125 7.56e-04

DNA uptake protein ComE or related DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 441164 [Multi-domain]  Cd Length: 72  Bit Score: 36.76  E-value: 7.56e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 516458286  74 ELIRLNGVGPKLALALMSslEVDELVRAVSAQDtsaLTKVPGVGKKTAERLL 125
Cdd:COG1555   22 ELQTLPGIGPKLAQRIVE--YREKNGPFKSVED---LLEVKGIGPKTLEKLK 68
uvrC PRK14666
excinuclease ABC subunit C; Provisional
 74-129 4.07e-03

excinuclease ABC subunit C; Provisional


Pssm-ID: 237782 [Multi-domain]  Cd Length: 694  Bit Score: 37.56  E-value: 4.07e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 516458286  74 ELIRLNGVGPKLALALMSSLEVDELVRAVSAQDtsaLTKVPGVGKKTAERLLVELK 129
Cdd:PRK14666 638 ELQRVEGIGPATARLLWERFGSLQAMAAAGEEG---LAAVPGIGPARAAALHEHLK 690
NT_POLXc cd00141
Nucleotidyltransferase (NT) domain of family X DNA Polymerases; X family polymerases fill in ...
 74-124 7.67e-03

Nucleotidyltransferase (NT) domain of family X DNA Polymerases; X family polymerases fill in short gaps during DNA repair. They are relatively inaccurate enzymes and play roles in base excision repair, in non-homologous end joining (NHEJ) which acts mainly to repair damage due to ionizing radiation, and in V(D)J recombination. This family includes eukaryotic Pol beta, Pol lambda, Pol mu, and terminal deoxyribonucleotidyl transferase (TdT). Pol beta and Pol lambda are primarily DNA template-dependent polymerases. TdT is a DNA template-independent polymerase. Pol mu has both template dependent and template independent activities. This subgroup belongs to the Pol beta-like NT superfamily. In the majority of enzymes in this superfamily, two carboxylates, Dx[D/E], together with a third more distal carboxylate, coordinate two divalent metal cations involved in a two-metal ion mechanism of nucleotide addition. These three carboxylate residues are fairly well conserved in this family.


Pssm-ID: 143386 [Multi-domain]  Cd Length: 307  Bit Score: 36.40  E-value: 7.67e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 516458286  74 ELIRLNGVGPKLA------LALMSSLEVDELVRAVSaQDTSALTKVPGVGKKTAERL 124
Cdd:cd00141   46 EAKKLPGIGKKIAekieeiLETGKLRKLEELREDVP-PGLLLLLRVPGVGPKTARKL 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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