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Conserved domains on  [gi|516510875|ref|WP_017899313|]
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MULTISPECIES: microcin C ABC transporter permease [Klebsiella]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15021 super family cl33063
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


The actual alignment was detected with superfamily member PRK15021:

Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 638.95  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875   1 MSFFSPVNQARWARFRHNRRGYWSLWLFLILFLCSLGAELLANDRPLLVQYRGQLYVPVLKNYTEQTFGGAFATAADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  81 PWLQHQLASHGWALWPPVRFGATTINFASTVPFPSPPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVL 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 161 AGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 241 LGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGIAAFLSVAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|.
gi 516510875 321 LTLLIFIGEAVRDAFDPSKAV 341
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKAV 341
 
Name Accession Description Interval E-value
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 638.95  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875   1 MSFFSPVNQARWARFRHNRRGYWSLWLFLILFLCSLGAELLANDRPLLVQYRGQLYVPVLKNYTEQTFGGAFATAADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  81 PWLQHQLASHGWALWPPVRFGATTINFASTVPFPSPPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVL 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 161 AGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 241 LGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGIAAFLSVAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|.
gi 516510875 321 LTLLIFIGEAVRDAFDPSKAV 341
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKAV 341
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 614.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875   1 MSFFSPVNQARWARFRHNRRGYWSLWLFLILFLCSLGAELLANDRPLLVQYRGQLYVPVLKNYTEQTFGGAFATAADYQD 80
Cdd:COG4239    1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  81 PWLQHQLASHGWALWPPVRFGATTINFASTVPFPSPPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVL 160
Cdd:COG4239   81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 161 AGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:COG4239  161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 241 LGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGIAAFLSVAVL 320
Cdd:COG4239  241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                        330       340
                 ....*....|....*....|
gi 516510875 321 LTLLIFIGEAVRDAFDPSKA 340
Cdd:COG4239  321 LSLLVFIGEAVRDAFDPRKT 340
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-337 2.73e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.97  E-value: 2.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  158 GVLAGAIQG-YYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPG----FWWLLAITVLFGWMTLVGVVRAEFLRTRNY 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  233 DYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGfglplGSPSLGELLLQGKNNLQAPWlGIA 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*
gi 516510875  313 AFLSVAVLLTLLIFIGEAVRDAFDP 337
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 141-324 1.77e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 81.94  E-value: 1.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 141 RISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSV--------VQPGFWWLLAITVL 212
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLfgvllgwgILPGLGLPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 213 FGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGsps 292
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG--- 158

                        170       180       190
                 ....*....|....*....|....*....|..
gi 516510875 293 LGELLLQGKNNLQAPWLGIAAFLSVAVLLTLL 324
Cdd:cd06261  159 PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-341 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 638.95  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875   1 MSFFSPVNQARWARFRHNRRGYWSLWLFLILFLCSLGAELLANDRPLLVQYRGQLYVPVLKNYTEQTFGGAFATAADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  81 PWLQHQLASHGWALWPPVRFGATTINFASTVPFPSPPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVL 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 161 AGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 241 LGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGIAAFLSVAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|.
gi 516510875 321 LTLLIFIGEAVRDAFDPSKAV 341
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKAV 341
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 614.47  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875   1 MSFFSPVNQARWARFRHNRRGYWSLWLFLILFLCSLGAELLANDRPLLVQYRGQLYVPVLKNYTEQTFGGAFATAADYQD 80
Cdd:COG4239    1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  81 PWLQHQLASHGWALWPPVRFGATTINFASTVPFPSPPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVL 160
Cdd:COG4239   81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 161 AGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQA 240
Cdd:COG4239  161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 241 LGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGIAAFLSVAVL 320
Cdd:COG4239  241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                        330       340
                 ....*....|....*....|
gi 516510875 321 LTLLIFIGEAVRDAFDPSKA 340
Cdd:COG4239  321 LSLLVFIGEAVRDAFDPRKT 340
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 116-336 5.09e-65

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 206.50  E-value: 5.09e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 116 PPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILL 195
Cdd:COG1173   54 PPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIAL 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 196 SSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSITT 275
Cdd:COG1173  134 VAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILA 213

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516510875 276 LTSLDFLGFGLPLGSPSLGELLLQGKNNLQ-APWLGIAAFLSVAVLLTLLIFIGEAVRDAFD 336
Cdd:COG1173  214 EAGLSFLGLGVQPPTPSWGTMLSEGRNYLLtAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 115-337 2.01e-32

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 122.64  E-value: 2.01e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 115 SPP--SASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLI 192
Cdd:PRK15406  74 SAPdmESGHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFV 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 193 ILLSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSS 272
Cdd:PRK15406 154 ILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSM 233

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516510875 273 ITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQ-APWLGIAAFLSVAVLLTLLIFIGEAVRDAFDP 337
Cdd:PRK15406 234 ILFESFLSFLGLGTQEPLSSWGALLSDGANSMEvSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDP 299
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 115-337 2.58e-29

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 114.06  E-value: 2.58e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 115 SPPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIIL 194
Cdd:PRK15082  74 AGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIA 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 195 LSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSIT 274
Cdd:PRK15082 154 VVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSII 233

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516510875 275 TLTSLDFLGFGLPLGSPSLGELLLQGKNNL-QAPwlGIAAFLSVAVLLTLLIF--IGEAVRDAFDP 337
Cdd:PRK15082 234 TAASLSFLGLGAQPPTPEWGAMLNEARADMvIAP--HVALFPSLAIFLTVLAFnlLGDGLRDALDP 297
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
116-337 4.09e-27

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 108.37  E-value: 4.09e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 116 PPSASNWLGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILL 195
Cdd:PRK09881  69 PPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMAL 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 196 SSVVQPGFW-WLLAITVLfGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSIT 274
Cdd:PRK09881 149 AAALGPSLFnAMLAIAIV-RIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAIL 227

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 516510875 275 TLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLgIAAFLSVAVLLTLLIF--IGEAVRDAFDP 337
Cdd:PRK09881 228 MAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWW-YCAFPGAAILLTAVGFnlFGDGIRDLLDP 291
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
123-337 2.62e-23

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 97.93  E-value: 2.62e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 123 LGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPG 202
Cdd:PRK10913  81 LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 203 FW-WLLAITVLfGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDF 281
Cdd:PRK10913 161 IVnAALALTFV-ALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGF 239

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 516510875 282 LGFGLPLGSPSLGELLLQGKNNLQAPWLgIAAFLSVAVLLTLLIF--IGEAVRDAFDP 337
Cdd:PRK10913 240 LGMGAQPPTPEWGTMLSDVLQFAQSAWW-VVTFPGLAILLTVLAFnlMGDGLRDALDP 296
nikC PRK10417
nickel transporter permease NikC; Provisional
 116-337 3.15e-22

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 94.35  E-value: 3.15e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 116 PPSASNWLGTDANGGDVLARILYGTRIS---VLFGLLLTLfssVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLI 192
Cdd:PRK10417  42 SPDAQHWLGTDHLGRDIFSRLMAGTRVSlgsVMACLLLVL---ALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILA 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 193 ILLSSVVQPGFWWLLAITVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSS 272
Cdd:PRK10417 119 FFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHM 198

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 273 ITTLTSLDFLGFGLPLGSPSLGELLLQGKN-----NLQAPWLGIAAFLSVAVLLTLlifiGEAVRDAFDP 337
Cdd:PRK10417 199 MLHVAGLSFLGLGVTAPTAEWGVMINDARQyiwtqPLLMFWPGLALFISVMAFNLL----GDALRDHLDP 264
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 158-337 2.73e-20

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 86.97  E-value: 2.73e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  158 GVLAGAIQG-YYGGKIDLWGQRFIEVWSGMPTLFLIILLSSVVQPG----FWWLLAITVLFGWMTLVGVVRAEFLRTRNY 232
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSilghGILPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875  233 DYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGfglplGSPSLGELLLQGKNNLQAPWlGIA 312
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG-----SWPGLGLLLIEAILGYDYPE-IQG 154

                         170       180
                  ....*....|....*....|....*
gi 516510875  313 AFLSVAVLLTLLIFIGEAVRDAFDP 337
Cdd:pfam00528 155 PVLAAALILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 141-324 1.77e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 81.94  E-value: 1.77e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 141 RISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTLFLIILLSSV--------VQPGFWWLLAITVL 212
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLfgvllgwgILPGLGLPALILAL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 213 FGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGsps 292
Cdd:cd06261   82 LLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG--- 158

                        170       180       190
                 ....*....|....*....|....*....|..
gi 516510875 293 LGELLLQGKNNLQAPWLGIAAFLSVAVLLTLL 324
Cdd:cd06261  159 PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 127-265 2.65e-10

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 60.47  E-value: 2.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 127 ANGGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGGKidlWGQRFIEVWS----GMPTLFLIILLSSV---- 198
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGS---WLDRLITVLAllgiSIPSFWLGLLLILLfavk 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 199 -----------VQPGFW------WLLAITVLFGWMTLVG-VVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPNAMVA 260
Cdd:COG0601  159 lgwlpvsgrvsPWEDFLdalrhlILPALTLALGSLAGIArLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIP 238


                 ....*
gi 516510875 261 TLTFL 265
Cdd:COG0601  239 VVTVL 243
PRK15111 PRK15111
peptide ABC transporter permease SapC;
116-336 4.11e-08

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 53.94  E-value: 4.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 116 PPSASNW------LGTDANGGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGGKIDLWGQRFIEVWSGMPTL 189
Cdd:PRK15111  65 PPSWSRYgevsffLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSL 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 190 FLIILLSSVVQPGfwwlLAITVLFGWMTLVG-VVRAEFLRTR---NYDYIRAAQALGVSDRQIILRHMLPNAMVATLTFL 265
Cdd:PRK15111 145 LLAIIVVAFAGPS----LSHAMFAVWLALLPrMVRSIYSAVHdelEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEI 220

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 516510875 266 PFILCSSITTLTSLDFLGFGLPLGSPSLGELLlqgKNNLQ----APWL----GIAAFLSVaVLLTLLifiGEAVRDAFD 336
Cdd:PRK15111 221 TRALSMAILDIAALGFLDLGAQLPSPEWGAML---GDSLEliyvAPWTvmlpGAAIMLSV-LLVNLL---GDGIRRAII 292
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 129-283 2.13e-03

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 39.73  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 129 GGDVLARILYGTRISVLFGLLLTLFSSVLGVLAGAIQGYYGG-KIDLWGQRFIEVWSGMPT-LFLIIL------------ 194
Cdd:PRK15133 122 SASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGsRFDVWSSAFIIIGYAIPAfLFAILLivffaggsyfdl 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516510875 195 --LSSVVQPGF----W--------WLLAI----TVLFGWMTLVGVVRAEFLRTRNYDYIRAAQALGVSDRQIILRHMLPN 256
Cdd:PRK15133 202 fpLRGLVSANFdslpWyqkitdylWHITLpvlaTVIGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRN 281

                        170       180       190
                 ....*....|....*....|....*....|....
gi 516510875 257 AMVATL-----TFLPFILCSS--ITTLTSLDFLG 283
Cdd:PRK15133 282 AMLLVIagfpaTFISMFFTGSllIEVMFSLNGLG 315
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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