|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
38-357 |
1.02e-76 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 239.07 E-value: 1.02e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 38 AKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQL 117
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 118 AYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQVVFTL 197
Cdd:COG0845 83 ELERYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAGTPLFTI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 198 AHDGDRDAVFEVVESAFLRPIDGDG-TVALLSNPSQKIAAKVREISPTIDSSTGTIKVKVAI-SSDAAIPLGAPVVGRFN 275
Cdd:COG0845 163 ADLDPLEVEFDVPESDLARLKVGQPvTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELpNPDGLLRPGMFVRVRIV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 276 Y-VSQDVIQLPWSAMTSKDGKPAVWIVDpASSAVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPGEIVSYVKE 354
Cdd:COG0845 243 LgERENALLVPASAVVRDGGGAYVFVVD-ADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVSGLQRLRDGAKVRVVEA 321
|
...
gi 516616581 355 ASK 357
Cdd:COG0845 322 AAP 324
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
33-350 |
9.22e-61 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 197.92 E-value: 9.22e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 33 VGVVVAKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQ 112
Cdd:TIGR01730 1 VTVATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 113 TQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQ 192
Cdd:TIGR01730 81 ELAQRSFERAERLVKRNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVTAGQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 193 VVFTLAHDGDRDAVFEVVESAFLRPIDGDG-TVALLSNPSQKIAAKVREISPTIDSSTGTIKVKVAISS-DAAIPLGAPV 270
Cdd:TIGR01730 161 TLATIVDLDPLEADFSVPERDLPQLRRGQTlTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVRATFPNpDGRLLPGMFG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 271 VGRFNYVSQ-DVIQLPWSAMTSKDGKPAVWIVDPASSaVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPGEIV 349
Cdd:TIGR01730 241 RVTISLKVRsSAIVVPTQAVIEDLNGKYVYVVKNDGK-VSKRPVEVGLRNGGYVEIESGLKAGDQIVTAGVVKLRDGAKV 319
|
.
gi 516616581 350 S 350
Cdd:TIGR01730 320 K 320
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
40-192 |
1.91e-22 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 95.95 E-value: 1.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 40 PEPLVQGGAVTGEVRA-RVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQLA 118
Cdd:pfam00529 1 LAPLTKGVEAPGRVVVsGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 516616581 119 YDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQ 192
Cdd:pfam00529 81 LDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQ 154
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
2-346 |
1.32e-21 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 94.78 E-value: 1.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 2 RTILVATAIVCAVGLGSCSDErgPTEPTAR---QVGVVVAKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQ 78
Cdd:PRK09859 4 RRKLLIPLLFCGAMLTACDDK--SAENAAAmtpEVGVVTLSPGSVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 79 SVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLE 158
Cdd:PRK09859 82 KVNQGDSLYQIDPAPLQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 159 TAQDTLSYTELKADADGMITARNAEVGQVAQAAQVVfTLAHDGDRDAVF--------------EVVESAFLRPIDGDGTV 224
Cdd:PRK09859 162 QATINLQYANVTSPITGVSGKSSVTVGALVTANQAD-SLVTVQRLDPIYvdltqsvqdflrmkEEVASGQIKQVQGSTPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 225 AL-LSNPSQKIAAKVREIS-PTIDSSTGTIKVKVAI-SSDAAIPLGAPVVGRFNYVS-QDVIQLPWSAMT-SKDGKPAVW 299
Cdd:PRK09859 241 QLnLENGKRYSQTGTLKFSdPTVDETTGSVTLRAIFpNPNGDLLPGMYVTALVDEGSrQNVLLVPQEGVThNAQGKATAL 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 516616581 300 IVDpASSAVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPG 346
Cdd:PRK09859 321 ILD-KDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPG 366
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| AcrA |
COG0845 |
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope ... |
38-357 |
1.02e-76 |
|
Multidrug efflux pump subunit AcrA (membrane-fusion protein) [Cell wall/membrane/envelope biogenesis, Defense mechanisms];
Pssm-ID: 440606 [Multi-domain] Cd Length: 324 Bit Score: 239.07 E-value: 1.02e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 38 AKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQL 117
Cdd:COG0845 3 VERGDVPETVEATGTVEARREVEVRARVSGRVEEVLVDEGDRVKKGQVLARLDPPDLQAALAQAQAQLAAAQAQLELAKA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 118 AYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQVVFTL 197
Cdd:COG0845 83 ELERYKALLKKGAVSQQELDQAKAALDQAQAALAAAQAALEQARANLAYTTIRAPFDGVVGERNVEPGQLVSAGTPLFTI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 198 AHDGDRDAVFEVVESAFLRPIDGDG-TVALLSNPSQKIAAKVREISPTIDSSTGTIKVKVAI-SSDAAIPLGAPVVGRFN 275
Cdd:COG0845 163 ADLDPLEVEFDVPESDLARLKVGQPvTVTLDAGPGKTFEGKVTFIDPAVDPATRTVRVRAELpNPDGLLRPGMFVRVRIV 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 276 Y-VSQDVIQLPWSAMTSKDGKPAVWIVDpASSAVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPGEIVSYVKE 354
Cdd:COG0845 243 LgERENALLVPASAVVRDGGGAYVFVVD-ADGKVERRPVTLGRRDGDQVEVLSGLKAGDRVVVSGLQRLRDGAKVRVVEA 321
|
...
gi 516616581 355 ASK 357
Cdd:COG0845 322 AAP 324
|
|
| RND_mfp |
TIGR01730 |
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion ... |
33-350 |
9.22e-61 |
|
RND family efflux transporter, MFP subunit; This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273776 [Multi-domain] Cd Length: 322 Bit Score: 197.92 E-value: 9.22e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 33 VGVVVAKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQ 112
Cdd:TIGR01730 1 VTVATVESETLANTLTFPGSLEAVDEADLAAEVAGKITKISVREGQKVKKGQVLARLDDDDYQLALQAALAQLAAAEAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 113 TQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQ 192
Cdd:TIGR01730 81 ELAQRSFERAERLVKRNAVSQADLDDAKAAVEAAQADLEAAKASLASAQLNLRYTEIRAPFDGTIGRRLVEVGAYVTAGQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 193 VVFTLAHDGDRDAVFEVVESAFLRPIDGDG-TVALLSNPSQKIAAKVREISPTIDSSTGTIKVKVAISS-DAAIPLGAPV 270
Cdd:TIGR01730 161 TLATIVDLDPLEADFSVPERDLPQLRRGQTlTVELDALPGEEFKGKLRFIDPRVDSGTGTVRVRATFPNpDGRLLPGMFG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 271 VGRFNYVSQ-DVIQLPWSAMTSKDGKPAVWIVDPASSaVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPGEIV 349
Cdd:TIGR01730 241 RVTISLKVRsSAIVVPTQAVIEDLNGKYVYVVKNDGK-VSKRPVEVGLRNGGYVEIESGLKAGDQIVTAGVVKLRDGAKV 319
|
.
gi 516616581 350 S 350
Cdd:TIGR01730 320 K 320
|
|
| EmrA |
COG1566 |
Multidrug resistance efflux pump EmrA [Defense mechanisms]; |
49-275 |
8.86e-33 |
|
Multidrug resistance efflux pump EmrA [Defense mechanisms];
Pssm-ID: 441174 [Multi-domain] Cd Length: 331 Bit Score: 124.78 E-value: 8.86e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 49 VTGEVRARVQTdLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQ---------------QT 113
Cdd:COG1566 37 ADGRVEARVVT-VAAKVSGRVTEVLVKEGDRVKKGQVLARLDPTDLQAALAQAEAQLAAAEAQlarleaelgaeaeiaAA 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 114 QAQLA------------YDRQQSLFRTQVTTRAALDQAQEALLTAQAS---------------------------TKSAQ 154
Cdd:COG1566 116 EAQLAaaqaqldlaqreLERYQALYKKGAVSQQELDEARAALDAAQAQleaaqaqlaqaqaglreeeelaaaqaqVAQAE 195
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 155 ALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQVVFTLAHDGDRDAVFEVVES--AFLRPidGD-GTVALLSNPS 231
Cdd:COG1566 196 AALAQAELNLARTTIRAPVDGVVTNLNVEPGEVVSAGQPLLTIVPLDDLWVEAYVPETdlGRVKP--GQpVEVRVDAYPD 273
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 516616581 232 QKIAAKVREISPTIDSSTG----------TIKVKVAISSDAAIPL--GAPVVGRFN 275
Cdd:COG1566 274 RVFEGKVTSISPGAGFTSPpknatgnvvqRYPVRIRLDNPDPEPLrpGMSATVEID 329
|
|
| CusB_dom_1 |
pfam00529 |
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ... |
40-192 |
1.91e-22 |
|
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.
Pssm-ID: 425733 [Multi-domain] Cd Length: 322 Bit Score: 95.95 E-value: 1.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 40 PEPLVQGGAVTGEVRA-RVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQLA 118
Cdd:pfam00529 1 LAPLTKGVEAPGRVVVsGNAKAVQPQVSGIVTRVLVKEGDRVKAGDVLFQLDPTDYQAALDSAEAQLAKAQAQVARLQAE 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 516616581 119 YDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQ 192
Cdd:pfam00529 81 LDRLQALESELAISRQDYDGATAQLRAAQAAVKAAQAQLAQAQIDLARRRVLAPIGGISRESLVTAGALVAQAQ 154
|
|
| PRK09859 |
PRK09859 |
multidrug transporter subunit MdtE; |
2-346 |
1.32e-21 |
|
multidrug transporter subunit MdtE;
Pssm-ID: 137559 [Multi-domain] Cd Length: 385 Bit Score: 94.78 E-value: 1.32e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 2 RTILVATAIVCAVGLGSCSDErgPTEPTAR---QVGVVVAKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQ 78
Cdd:PRK09859 4 RRKLLIPLLFCGAMLTACDDK--SAENAAAmtpEVGVVTLSPGSVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 79 SVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLE 158
Cdd:PRK09859 82 KVNQGDSLYQIDPAPLQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAVE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 159 TAQDTLSYTELKADADGMITARNAEVGQVAQAAQVVfTLAHDGDRDAVF--------------EVVESAFLRPIDGDGTV 224
Cdd:PRK09859 162 QATINLQYANVTSPITGVSGKSSVTVGALVTANQAD-SLVTVQRLDPIYvdltqsvqdflrmkEEVASGQIKQVQGSTPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 225 AL-LSNPSQKIAAKVREIS-PTIDSSTGTIKVKVAI-SSDAAIPLGAPVVGRFNYVS-QDVIQLPWSAMT-SKDGKPAVW 299
Cdd:PRK09859 241 QLnLENGKRYSQTGTLKFSdPTVDETTGSVTLRAIFpNPNGDLLPGMYVTALVDEGSrQNVLLVPQEGVThNAQGKATAL 320
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 516616581 300 IVDpASSAVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPG 346
Cdd:PRK09859 321 ILD-KDDVVQLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPG 366
|
|
| PRK11578 |
PRK11578 |
macrolide transporter subunit MacA; Provisional |
2-244 |
9.57e-21 |
|
macrolide transporter subunit MacA; Provisional
Pssm-ID: 183211 [Multi-domain] Cd Length: 370 Bit Score: 92.14 E-value: 9.57e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 2 RTILVATAIVCAVGLGSCSDERGPtEPTARQVGVVvakPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVK 81
Cdd:PRK11578 9 KRYLIALVIVLAGGITLWRILNAP-VPTYQTLIVR---PGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 82 AGQLLARIDPE-------EQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQVTTRAALDQAQEALL-------TAQ 147
Cdd:PRK11578 85 KDQLLGVIDPEqaenqikEVEATLMELRAQRQQAEAELKLARVTLSRQQRLAKTQAVSQQDLDTAATELAvkqaqigTID 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 148 ASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQV---AQAAQVVFTLAHDGDRDAVFEVVES--AFLRPiDGDG 222
Cdd:PRK11578 165 AQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTviaAQQAPNILTLADMSTMLVKAQVSEAdvIHLKP-GQKA 243
|
250 260
....*....|....*....|..
gi 516616581 223 TVALLSNPSQKIAAKVREISPT 244
Cdd:PRK11578 244 WFTVLGDPLTRYEGVLKDILPT 265
|
|
| PRK03598 |
PRK03598 |
putative efflux pump membrane fusion protein; Provisional |
58-198 |
8.01e-20 |
|
putative efflux pump membrane fusion protein; Provisional
Pssm-ID: 235136 [Multi-domain] Cd Length: 331 Bit Score: 88.87 E-value: 8.01e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 58 QTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPE-------EQKAELDVAAANLQ-------------------SAEAQ 111
Cdd:PRK03598 43 TVNLGFRVGGRLASLAVDEGDAVKAGQVLGELDAApyenalmQAKANVSVAQAQLDlmlagyrdeeiaqaraavkQAQAA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 112 QTQAQLAYDRQQSLFRTQVTTRAALDQ--------------AQEAL------------LTAQASTKSAQALLETAQDTLS 165
Cdd:PRK03598 123 YDYAQNFYNRQQGLWKSRTISANDLENarssrdqaqatlksAQDKLsqyregnrpqdiAQAKASLAQAQAALAQAELNLQ 202
|
170 180 190
....*....|....*....|....*....|...
gi 516616581 166 YTELKADADGMITARNAEVGQVAQAAQVVFTLA 198
Cdd:PRK03598 203 DTELIAPSDGTILTRAVEPGTMLNAGSTVFTLS 235
|
|
| PRK15030 |
PRK15030 |
multidrug efflux RND transporter periplasmic adaptor subunit AcrA; |
32-346 |
8.67e-20 |
|
multidrug efflux RND transporter periplasmic adaptor subunit AcrA;
Pssm-ID: 184990 [Multi-domain] Cd Length: 397 Bit Score: 89.77 E-value: 8.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 32 QVGVVVAKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQ 111
Cdd:PRK15030 39 AVGVVTVKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDSAKGDLAKAQAA 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 112 QTQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAA 191
Cdd:PRK15030 119 ANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNG 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 192 QVVfTLAHDGDRDAVF-EVVESA--FLR-----------PIDGDGTVALLSNPSQKI-AAKVREISP-TIDSSTGTIKVK 255
Cdd:PRK15030 199 QAT-ALATVQQLDPIYvDVTQSSndFLRlkqelangtlkQENGKAKVSLITSDGIKFpQDGTLEFSDvTVDQTTGSITLR 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 256 VAI-SSDAAIPLGAPVVGRFNY-VSQDVIQLPWSAMTSKDGKPAVWIVDPASSAVSARAVDVSGYETGSFIVKSGVSEGE 333
Cdd:PRK15030 278 AIFpNPDHTLLPGMFVRARLEEgLNPNAILVPQQGVTRTPRGDATVLVVGADDKVETRPIVASQAIGDKWLVTEGLKAGD 357
|
330
....*....|...
gi 516616581 334 VVVADGTKFLRPG 346
Cdd:PRK15030 358 RVVISGLQKVRPG 370
|
|
| PRK09578 |
PRK09578 |
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit; |
5-356 |
1.33e-18 |
|
MexX/AxyX family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 169982 [Multi-domain] Cd Length: 385 Bit Score: 86.00 E-value: 1.33e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 5 LVATAIVCAVGLGSCSDERGPTEPTA-RQVGVVVAKPEPLVQGGAVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVKAG 83
Cdd:PRK09578 9 LLLAALVALFVLAGCGKGDSDAAAAApREATVVTVRPTSVPMTVELPGRLDAYRQAEVRARVAGIVTARTYEEGQEVKQG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 84 QLLARIDPEEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDT 163
Cdd:PRK09578 89 AVLFRIDPAPLKAARDAAAGALAKAEAAHLAALDKRRRYDDLVRDRAVSERDYTEAVADERQAKAAVASAKAELARAQLQ 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 164 LSYTELKADADGMitARNAEVGQ---VAQAAQVVFTLAHD------------GDRDAVFEVVESAFLRPI-DGDGTVALL 227
Cdd:PRK09578 169 LDYATVTAPIDGR--ARRALVTEgalVGQDQATPLTTVEQldpiyvnfsqpaADVEALRRAVKSGRATGIaQQDVAVTLV 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 228 SNPSQKIAAKVREI--SPTIDSSTGTIKVKVAISS-DAAIPLGAPVVGRFNY-VSQDVIQLPWSAMTSKDGKPAVWIVDP 303
Cdd:PRK09578 247 RADGSEYPLKGKLLfsDLAVDPTTDTVAMRALFPNpERELLPGAYVRIALDRaVNPRAILVPRDALLRTADSASVKVVGQ 326
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 516616581 304 ASSaVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPGEIVSYVKEAS 356
Cdd:PRK09578 327 NGK-VRDVEVEADQMSGRDWIVTRGLAGGERVIVDNAAQFAPGTAVKAVERAP 378
|
|
| PRK11556 |
PRK11556 |
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit; |
51-352 |
3.69e-18 |
|
MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit;
Pssm-ID: 183194 [Multi-domain] Cd Length: 415 Bit Score: 84.84 E-value: 3.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 51 GEVRARVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQV 130
Cdd:PRK11556 80 GTVTAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPRPFKVALAQAQGQLAKDQATLANARRDLARYQQLAKTNL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 131 TTRAALDqAQEALLT-AQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQVAQAAQ----VVFTLAHdgDRDA 205
Cdd:PRK11556 160 VSRQELD-AQQALVSeTEGTIKADEASVASAQLQLDYSRITAPISGRVGLKQVDVGNQISSGDttgiVVITQTH--PIDL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 206 VFEVVESAFLRPIDGDGTVALLS------NPSQKIAA-KVREISPTIDSSTGTIKVKVAISS--DAAIPlgAPVVGRFNY 276
Cdd:PRK11556 237 VFTLPESDIATVVQAQKAGKPLVveawdrTNSKKLSEgTLLSLDNQIDATTGTIKLKARFNNqdDALFP--NQFVNARML 314
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 516616581 277 VS--QDVIQLPWSAMTSKDGKPAVWIVDpASSAVSARAVDVSGYETGSFIVKSGVSEGEVVVADGTKFLRPGEIVSYV 352
Cdd:PRK11556 315 VDtlQNAVVIPTAALQMGNEGHFVWVLN-DENKVSKHLVTPGIQDSQKVVISAGLSAGDRVVTDGIDRLTEGAKVEVV 391
|
|
| PRK10476 |
PRK10476 |
multidrug transporter subunit MdtN; |
65-273 |
8.24e-13 |
|
multidrug transporter subunit MdtN;
Pssm-ID: 182488 [Multi-domain] Cd Length: 346 Bit Score: 68.51 E-value: 8.24e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 65 VSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQ-------------------------QTQAQLA- 118
Cdd:PRK10476 55 VGGRIVELAVTENQAVKKGDLLFRIDPRPYELTVAQAQADLALADAQimttqrsvdaersnaasaneqveraRANAKLAt 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 119 -------------YDRQQSLFRTQVTTRAALDQAQEALLTAQAST-------------KSAQALLETAQDTLSYTELKAD 172
Cdd:PRK10476 135 rtlerlepllakgYVSAQQVDQARTAQRDAEVSLNQALLQAQAAAaavggvdalvaqrAAREAALAIAELHLEDTTVRAP 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 173 ADGMITARNAEVGQVAQAAQVVFTLAHDGDRDAVfevvesAFLRPID------GD-GTVALLSNPSQKIAAKVREISPTI 245
Cdd:PRK10476 215 FDGRVVGLKVSVGEFAAPMQPIFTLIDTDHWYAI------ANFRETDlknirvGDcATVYSMIDRGRPFEGKVDSIGWGV 288
|
250 260
....*....|....*....|....*...
gi 516616581 246 DSSTGTIkvkvaissdaaIPLGAPVVGR 273
Cdd:PRK10476 289 LPDDGGN-----------VPRGLPYVPR 305
|
|
| HlyD_D23 |
pfam16576 |
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and ... |
55-259 |
4.12e-11 |
|
Barrel-sandwich domain of CusB or HlyD membrane-fusion; HlyD_D23 is the combined domains 2 and 3 of the membrane-fusion proteins CusB and HlyD, which forms a barrel-sandwich. CusB and HlyD proteins are membrane fusion proteins of the CusCFBA copper efflux system in E.coli and related bacteria. The whole molecule hinges between D2 and D3. Efflux systems of this resistance-nodulation-division group - RND - have been developed to excrete poisonous metal ions, and in E.coli the only one that deals with silver and copper is the CusA transporter. The transporter CusA works in conjunction with a periplasmic component that is a membrane fusion protein, eg CusB, and an outer-membrane channel component CusC in a CusABC complex driven by import of protons.
Pssm-ID: 435440 [Multi-domain] Cd Length: 214 Bit Score: 61.75 E-value: 4.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 55 ARVQTdlsfRVSGKIvERL--VEVGQSVKAGQLLARID-PEEQKAELD-VAAANLQSAEAQQTQAQLAYDRQQSLfrtqv 130
Cdd:pfam16576 20 AHVHA----RVEGWI-EKLyvNATGDPVKKGQPLAELYsPELVAAQQEyLLALRSGDALSKSELLRAARQRLRLL----- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 131 ttraaldQAQEALLTAQASTKSAQalletaqdtlSYTELKADADGMITARNAEVGQVAQAAQVVFTLAhdgDRDAV---F 207
Cdd:pfam16576 90 -------GMPEAQIAELERTGKVQ----------PTVTVYAPISGVVTELNVREGMYVQPGDTLFTIA---DLSTVwveA 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 516616581 208 EVVES--AFLRPidGD-GTVALLSNPSQKIAAKVREISPTIDSSTGTIKVKVAIS 259
Cdd:pfam16576 150 DVPEQdlALVKV--GQpAEVTLPALPGKTFEGKVDYIYPTLDPKTRTVRVRIELP 202
|
|
| PRK10559 |
PRK10559 |
p-hydroxybenzoic acid efflux pump subunit AaeA; |
65-186 |
7.44e-09 |
|
p-hydroxybenzoic acid efflux pump subunit AaeA;
Pssm-ID: 182548 [Multi-domain] Cd Length: 310 Bit Score: 56.29 E-value: 7.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 65 VSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLfRTQVTTRAALDQAQEALL 144
Cdd:PRK10559 54 VSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALAEAEADVAYYQVLAQEKRREAGRRNRL-GVQAMSREEIDQANNVLQ 132
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 516616581 145 TAQASTKSAQALLETAQDTLSYTELKADADGMITARNAEVGQ 186
Cdd:PRK10559 133 TVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGE 174
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
168-269 |
1.67e-08 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 51.59 E-value: 1.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 168 ELKADADGMITARNAEVGQVAQAAQVVFTLAHDGDRDAVFEV--VESAFLRPiDGDGTVALLSNPSQKIAAKVREISPTI 245
Cdd:pfam13437 1 TIRAPVDGVVAELNVEEGQVVQAGDPLATIVPPDRLLVEAFVpaADLGSLKK-GQKVTLKLDPGSDYTLEGKVVRISPTV 79
|
90 100
....*....|....*....|....
gi 516616581 246 DSSTGTIKVKVAISSDAAIPLGAP 269
Cdd:pfam13437 80 DPDTGVIPVRVSIENPKTPIPLLP 103
|
|
| Biotin_lipoyl_2 |
pfam13533 |
Biotin-lipoyl like; |
61-106 |
8.97e-08 |
|
Biotin-lipoyl like;
Pssm-ID: 433286 Cd Length: 50 Bit Score: 48.21 E-value: 8.97e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 516616581 61 LSFRVSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQ 106
Cdd:pfam13533 5 IASPVSGKVVAVNVKEGQQVKKGDVLATLDSPELQLQLQQAEAQLA 50
|
|
| Surf_Exclu_PgrA |
TIGR04320 |
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ... |
92-174 |
6.31e-06 |
|
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.
Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 47.41 E-value: 6.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 92 EEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQVTTRA-----ALDQAQEALLTAQASTKSAQALLETAQDTLSy 166
Cdd:TIGR04320 264 ATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELAnaqaqALQTAQNNLATAQAALANAEARLAKAKEALA- 342
|
....*...
gi 516616581 167 tELKADAD 174
Cdd:TIGR04320 343 -NLNADLA 349
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
92-192 |
7.40e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.46 E-value: 7.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 92 EEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQASTKSAQALLETAQDTLsyTELKA 171
Cdd:COG1196 340 EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEAL--LERLE 417
|
90 100
....*....|....*....|.
gi 516616581 172 DADGMITARNAEVGQVAQAAQ 192
Cdd:COG1196 418 RLEEELEELEEALAELEEEEE 438
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
71-203 |
2.24e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 39.90 E-value: 2.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 71 ERLVEVG-QSVKAGQLLARIDP-EEQKAELDVAAANLQSAEAQQTQAQLAYDRQQSLFRTQVTTRAALDQAQEALLTAQa 148
Cdd:COG4913 651 QRLAEYSwDEIDVASAEREIAElEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEEL- 729
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 516616581 149 stKSAQALLETAQDtLSYTELKADADgmitARNAEVGQVAQAAQVVFTLAHDGDR 203
Cdd:COG4913 730 --DELQDRLEAAED-LARLELRALLE----ERFAAALGDAVERELRENLEERIDA 777
|
|
| PRK09783 |
PRK09783 |
copper/silver efflux system membrane fusion protein CusB; Provisional |
169-339 |
2.31e-03 |
|
copper/silver efflux system membrane fusion protein CusB; Provisional
Pssm-ID: 236625 [Multi-domain] Cd Length: 409 Bit Score: 39.47 E-value: 2.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 169 LKADADGMITARNAEVGQVAQAAQVVftlAHDGDRDAVF---EVVES-AFLRPIDGDGTVALLSNPSQKIAAKVREISPT 244
Cdd:PRK09783 212 LKAPIDGVITAFDLRAGMNIAKDNVV---AKIQGMDPVWvtaAIPESiAWLVKDASQFTLTVPARPDKTFTIRKWTLLPS 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 245 IDSSTGTIKVKVAISS-DAAIPLGAPVVGRFNYVSQDVIQLPWSAMTSKDGKPAVWIVDPASSAVSARaVDVSGYETGSF 323
Cdd:PRK09783 289 VDAATRTLQLRLEVDNaDEALKPGMNAWLQLNTASEPMLLIPSQALIDTGSEQRVITVDADGRFVPKR-VAVFQESQGVT 367
|
170
....*....|....*.
gi 516616581 324 IVKSGVSEGEVVVADG 339
Cdd:PRK09783 368 AIRSGLAEGEKVVSSG 383
|
|
| Surf_Exclu_PgrA |
TIGR04320 |
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ... |
94-165 |
2.47e-03 |
|
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.
Pssm-ID: 275124 [Multi-domain] Cd Length: 356 Bit Score: 39.32 E-value: 2.47e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516616581 94 QKAELDVAAANLQSAEAQQTQAQLAYDRQQslfrtqvttrAALDQAQEALLTAQASTKSAQALLETAQDTLS 165
Cdd:TIGR04320 245 DKTPIPNPPNSLAALQAKLATAQADLAAAQ----------TALNTAQAALTSAQTAYAAAQAALATAQKELA 306
|
|
| PRK09282 |
PRK09282 |
pyruvate carboxylase subunit B; Validated |
15-102 |
3.99e-03 |
|
pyruvate carboxylase subunit B; Validated
Pssm-ID: 236449 [Multi-domain] Cd Length: 592 Bit Score: 39.06 E-value: 3.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 15 GLGSCSDERGPTEPTARQVGVVVAKPEPLVqggaVTGEVRARVQTDLSFRVSGKIVERLVEVGQSVKAGQLLARIdpEEQ 94
Cdd:PRK09282 483 GVKAEGKRPFYLRVDGMPEEVVVEPLKEIV----VGGRPRASAPGAVTSPMPGTVVKVKVKEGDKVKAGDTVLVL--EAM 556
|
....*...
gi 516616581 95 KAELDVAA 102
Cdd:PRK09282 557 KMENEIQA 564
|
|
| PTS_EIIA_1 |
pfam00358 |
phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; |
67-97 |
4.07e-03 |
|
phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1;
Pssm-ID: 459779 [Multi-domain] Cd Length: 121 Bit Score: 36.59 E-value: 4.07e-03
10 20 30
....*....|....*....|....*....|.
gi 516616581 67 GKIVERLVEVGQSVKAGQLLARIDPEEQKAE 97
Cdd:pfam00358 81 GEGFESLVKEGDKVKAGDLLLEFDLEAIKAA 111
|
|
| PRK05704 |
PRK05704 |
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase; |
32-118 |
6.40e-03 |
|
2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase;
Pssm-ID: 235571 [Multi-domain] Cd Length: 407 Bit Score: 38.28 E-value: 6.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516616581 32 QVGVVVAKPEPLV--QGGAVTGEVRARVqtdlsfrvSGKIVERLVEVGQSVKAGQLLARIDPEEQKAELDVAAANLQSAE 109
Cdd:PRK05704 25 KPGDAVKRDEVLVeiETDKVVLEVPAPA--------AGVLSEILAEEGDTVTVGQVLGRIDEGAAAGAAAAAAAAAAAAA 96
|
....*....
gi 516616581 110 AQQTQAQLA 118
Cdd:PRK05704 97 AAPAQAQAA 105
|
|
| HlyD_3 |
pfam13437 |
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator ... |
65-113 |
7.06e-03 |
|
HlyD family secretion protein; This is a family of largely bacterial haemolysin translocator HlyD proteins.
Pssm-ID: 433206 [Multi-domain] Cd Length: 104 Bit Score: 35.80 E-value: 7.06e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 516616581 65 VSGKIVERLVEVGQSVKAGQLLARI-DPEEQKAELDVAAANLQSAEAQQT 113
Cdd:pfam13437 6 VDGVVAELNVEEGQVVQAGDPLATIvPPDRLLVEAFVPAADLGSLKKGQK 55
|
|
| |
