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Conserved domains on  [gi|516735075|ref|WP_018073919|]
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TonB-dependent hemoglobin/transferrin/lactoferrin family receptor [Rhizobium ruizarguesonis]

Protein Classification

porin family protein( domain architecture ID 229388)

porin family protein is a member of a large superfamily consisting of classical (gram-negative ) porins which are non-specific channels for small hydrophillic molecules, maltoporin-like channels which have specificities for various sugars, and ligand-gated protein channels which cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
OM_channels super family cl21487
Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in ...
46-750 3.57e-116

Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20), which associate as trimers. Maltoporin-like channels have specificities for various sugars and form 18 beta-stranded barrels (18,22), which associate as trimers. Ligand-gated protein channels cooperate with a TonB associated inner membrane complex to actively transport ligands via the proton motive force and they form monomeric, (22,24) barrels. The 150-200 N-terminal residues form a plug that blocks the channel from the periplasmic end.


The actual alignment was detected with superfamily member TIGR01786:

Pssm-ID: 473880 [Multi-domain]  Cd Length: 715  Bit Score: 366.74  E-value: 3.57e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   46 QKIVVKGKRAAPGSVAD---TPVSTE-ITDKKLDEKQVTNIEDLGRSVdPGINASRG----DAGINLRGLSGPRILTIVD 117
Cdd:TIGR01786   1 DTITVTATRTADPQRRDlsvTPASVSvISREQLKSQQVRNLRDLLRYE-PGVSVVEGgrggSQGINIRGLDKNRVAVLVD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  118 GIPIPYlSNSSRQGAFAPANangggdTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDLIPVGRDWGAIVKST 197
Cdd:TIGR01786  80 GIRQNT-SYGGQGSTFYAIN------SIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLG 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  198 YDSEDRSISGSAAAAKKIGNTSILFQGGYRKGHE-RDNMGDSDSYGRYRTESDPADFDQHNLLFKLRQEFEGGHRLGLTA 276
Cdd:TIGR01786 153 YSSANNRFTQSVAAAGRNDDVDALVQATYRRGHElKNGNKANIGNESKRSKPNPSDYKSQSFLAKLGWQLNDAHRLGLSL 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  277 ERFRRDLQTDK--RDLQGTGRTYMIDNYDARELNDRD----RVSLDYDYeaTSSDAFFTSARAVLYWQDLK---KESGTN 347
Cdd:TIGR01786 233 EYTQTDYDEPEmtNTSYLTKPLGAPLLSSTVVLGDSKtrdrRTGLDYEL--NPDNSWLDTVKLALDKQYIQlynYLNATS 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  348 GRTAANVAYGRTNeiENKTWGFNGTVTKDF--EYSNVRHSVKATLEATTSDwTQYSSALCPTPTTCPSLN-NQSEVPDVE 424
Cdd:TIGR01786 311 ASDYPGVDKNGRY--KDKYDYYTLGFDTNNkiEFSVHSLSLTYGLDRFKDK-VSTGDSRRNLPTAAYNLYgYEGENRPVK 387
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  425 SKTIGLSIEDKIEFGDtNFALTPGIRFDWFSYDPSTSGGFASNPalakfgtlSDRSDQHVSPKVLATYELTPDVQLYTQL 504
Cdd:TIGR01786 388 GSNFGLFLQDNIKLGD-WLSLSAGLRYDHYKTDPKADESKDYGA--------ISKTYSRWSPSLGLTYKPTPWLTLYYSY 458
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  505 SSAFRAPTVDELYSRFYNAGG-NYAQLGNPDLKPETGYGVEMGANFDTGDFNGRLAVFHNRYHNFIETV------TSVNA 577
Cdd:TIGR01786 459 SQGFRAPSFDELYGTGAHPGGgPYTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGigvtakGNMAQ 538
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  578 TTGITEFNYTNVSSVTISGIEASA----DKTFNNGINLHAALAYAY--GRNEETTQRLRSVAPFKAIVGGGW--SNETFG 649
Cdd:TIGR01786 539 VGSNTITNYVNIDNARIRGIELSGrydlGSFFSGPDGWTTTLKYGYtkGKDSDTNPWLNAITPLKVVLGLGYdhPDEKWG 618
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  650 FDLSSTLSAGMLTDHLNTPVTNTADT----TFDAPGYAIVDLTGWWTPdqVPGLRVQAGVYNIFDQEYFNALAVRDVNLI 725
Cdd:TIGR01786 619 VGLTLTFSGAKDAVDAYATYYENGEAakagPLRTPSYTVVDLYGYYKP--NKNLTLRFGVYNLLDRKYTTWESARQAGPL 696
                         730       740
                  ....*....|....*....|....*
gi 516735075  726 STasqprdWYSEPGRTFKVSLTKTF 750
Cdd:TIGR01786 697 AT------GYTAPGRNYKASVEYKF 715
 
Name Accession Description Interval E-value
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
46-750 3.57e-116

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 366.74  E-value: 3.57e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   46 QKIVVKGKRAAPGSVAD---TPVSTE-ITDKKLDEKQVTNIEDLGRSVdPGINASRG----DAGINLRGLSGPRILTIVD 117
Cdd:TIGR01786   1 DTITVTATRTADPQRRDlsvTPASVSvISREQLKSQQVRNLRDLLRYE-PGVSVVEGgrggSQGINIRGLDKNRVAVLVD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  118 GIPIPYlSNSSRQGAFAPANangggdTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDLIPVGRDWGAIVKST 197
Cdd:TIGR01786  80 GIRQNT-SYGGQGSTFYAIN------SIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLG 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  198 YDSEDRSISGSAAAAKKIGNTSILFQGGYRKGHE-RDNMGDSDSYGRYRTESDPADFDQHNLLFKLRQEFEGGHRLGLTA 276
Cdd:TIGR01786 153 YSSANNRFTQSVAAAGRNDDVDALVQATYRRGHElKNGNKANIGNESKRSKPNPSDYKSQSFLAKLGWQLNDAHRLGLSL 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  277 ERFRRDLQTDK--RDLQGTGRTYMIDNYDARELNDRD----RVSLDYDYeaTSSDAFFTSARAVLYWQDLK---KESGTN 347
Cdd:TIGR01786 233 EYTQTDYDEPEmtNTSYLTKPLGAPLLSSTVVLGDSKtrdrRTGLDYEL--NPDNSWLDTVKLALDKQYIQlynYLNATS 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  348 GRTAANVAYGRTNeiENKTWGFNGTVTKDF--EYSNVRHSVKATLEATTSDwTQYSSALCPTPTTCPSLN-NQSEVPDVE 424
Cdd:TIGR01786 311 ASDYPGVDKNGRY--KDKYDYYTLGFDTNNkiEFSVHSLSLTYGLDRFKDK-VSTGDSRRNLPTAAYNLYgYEGENRPVK 387
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  425 SKTIGLSIEDKIEFGDtNFALTPGIRFDWFSYDPSTSGGFASNPalakfgtlSDRSDQHVSPKVLATYELTPDVQLYTQL 504
Cdd:TIGR01786 388 GSNFGLFLQDNIKLGD-WLSLSAGLRYDHYKTDPKADESKDYGA--------ISKTYSRWSPSLGLTYKPTPWLTLYYSY 458
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  505 SSAFRAPTVDELYSRFYNAGG-NYAQLGNPDLKPETGYGVEMGANFDTGDFNGRLAVFHNRYHNFIETV------TSVNA 577
Cdd:TIGR01786 459 SQGFRAPSFDELYGTGAHPGGgPYTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGigvtakGNMAQ 538
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  578 TTGITEFNYTNVSSVTISGIEASA----DKTFNNGINLHAALAYAY--GRNEETTQRLRSVAPFKAIVGGGW--SNETFG 649
Cdd:TIGR01786 539 VGSNTITNYVNIDNARIRGIELSGrydlGSFFSGPDGWTTTLKYGYtkGKDSDTNPWLNAITPLKVVLGLGYdhPDEKWG 618
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  650 FDLSSTLSAGMLTDHLNTPVTNTADT----TFDAPGYAIVDLTGWWTPdqVPGLRVQAGVYNIFDQEYFNALAVRDVNLI 725
Cdd:TIGR01786 619 VGLTLTFSGAKDAVDAYATYYENGEAakagPLRTPSYTVVDLYGYYKP--NKNLTLRFGVYNLLDRKYTTWESARQAGPL 696
                         730       740
                  ....*....|....*....|....*
gi 516735075  726 STasqprdWYSEPGRTFKVSLTKTF 750
Cdd:TIGR01786 697 AT------GYTAPGRNYKASVEYKF 715
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
45-723 2.50e-86

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 285.95  E-value: 2.50e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  45 LQKIVVKGKRAApGSVADTPVS-TEITDKKLDEKQVTNIEDLGRSVdPGINASR---GDAGINLRGLSG--PRILTIVDG 118
Cdd:COG1629    1 LEEVVVTATRTD-ESLQDVPGSvSVISREQLEDQPATDLGDLLRRV-PGVSVTSaggGAGQISIRGFGGggNRVLVLVDG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 119 IPIPYlsnssrqgafaPANANGGGDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDlipvgrDWGAIVKSTY 198
Cdd:COG1629   79 VPLND-----------PSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASY 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 199 DSEDRsISGSAAAAKKIGNTSILFQGGYRkgherdnmgDSDSYGryrtesDPADFDQHNLLFKLRQEFEGGHRLGLTAER 278
Cdd:COG1629  142 GSYGT-YRASLSLSGGNGKLAYRLSASYR---------DSDGYR------DNSDSDRYNLRAKLGYQLGDDTRLTLSASY 205
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 279 FRRDLQTD----KRDLQGTGRTYMIDN--YDARELNDRDRVSLDYDYEATSSDAFFtsaRAVLYWQ-DLKKESGTNGRTA 351
Cdd:COG1629  206 SDSDQDSPgyltLAALRPRGAMDDGTNpySNDTDDNTRDRYSLSLEYEHLGDGLKL---SASAYYRyDDTDLDSDFTPTP 282
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 352 ANVAYGRTNEIENKTWGFNGTVTKDFEYsNVRHSVKATLEATTSDWTQYSSALCPTPTTCPSLNNQSEVpDVESKTIGLS 431
Cdd:COG1629  283 ADGGTLEQTDFDNRTYGLELRLTYDLGF-GGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGADD-DGTTTSLALY 360
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 432 IEDKIEFGDtNFALTPGIRFDWFSYDPStsggfasNPALAKFGTLSDRSDQHVSPKVLATYELTPDVQLYTQLSSAFRAP 511
Cdd:COG1629  361 AQDTYKLTD-KLTLTAGLRYDYVSYDVD-------DTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAP 432
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 512 TVDELYSRfynaGGNYAQLGNPDLKPETGYGVEMGA--NFDTGDFNGRLAVFHNRYHNFIETVTSVNATTGITefNYTNV 589
Cdd:COG1629  433 TFGELYAN----GTDPYSVGNPDLKPETSTNYELGLryRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFST--YYTNA 506
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 590 SSVTISGIEASADKTFNNGINLHAALAYAYGRNEETT--------QRLRSVAPFKAIVGGGWS-NETFGFDLSSTLSAGM 660
Cdd:COG1629  507 GKARSYGVELELSYQLTPGLSLNASYSYTDAKFDDDTdgsadldgNRLPGVPPLTANLGLTYEfPGGWSLGLGVRYVGDR 586
                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516735075 661 LTDHLNTPVTNtadttfdaPGYAIVDLTGWWTPDqvPGLRVQAGVYNIFDQEYFNALAVRDVN 723
Cdd:COG1629  587 YLDDANTQGAP--------GGYTLVDLGAGYRFG--DNLTLSLGVDNLFDKKYATSLSVRASN 639
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
65-750 1.76e-71

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 245.44  E-value: 1.76e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  65 VSTEITDKKLDEKQVTNIEDLGRSVdPGINASRGDAG----INLRGLSGPRILTIVDGIPIpylsnssrqgAFAPANANG 140
Cdd:cd01347    1 SVSVITAEDIEKQPATSLADLLRRI-PGVSVTRGGGGggstISIRGFGPDRTLVLVDGLPL----------ASSNYGRGV 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 141 GGDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPedlipvGRDWGAIVKSTYDSEDRSISGS-----AAAAKKI 215
Cdd:cd01347   70 DLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRP------TDEFGGSVTAGYGSDNSGSSGGggfdvSGALADD 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 216 GNTSILFQGGYRKGherdnmgdsDSYGRYRTESDPADFDQHNLLFKLRQEFEGGHRLGLTAERFRRDLQTDKRDLQGTGR 295
Cdd:cd01347  144 GAFGARLYGAYRDG---------DGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGT 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 296 TYMI--------DNYDARELNDRDRVSLDYDYEATSSDAFFTSaRAVLYWQDLKKESGTNGRTAANVAYGRTNEIENKT- 366
Cdd:cd01347  215 GSSLgggpssntNGDRDWDYRDRYRKRASLGLEHDLNDTGWTL-RANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSs 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 367 ------WGFNGTVTKDFEYSNVRHSVKATLEATTSDWTQYSSALcptpttcpslnnqsevpdvesktiglSIEDKIEFGD 440
Cdd:cd01347  294 erdttqLGFDAGLNAPFGTGPVAHTLTLGVEYRREELDEKQTAL--------------------------YAQDTIELTD 347
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 441 tNFALTPGIRFDWFSYDPSTSGGFasnpalakfGTLSDRSDQHVSPKVLATYELTPDVQLYTQLSSAFRAPTVDELYSRF 520
Cdd:cd01347  348 -DLTLTLGLRYDHYDQDSKDTIAG---------GTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGG 417
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 521 YNAGGNYaqLGNPDLKPETGYGVEMGANFDTG-DFNGRLAVFHNRYHNFIETVTSVNATTGITefNYTNVSSVTISGIEA 599
Cdd:cd01347  418 SHGGTAA--VGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVSTPTNTGLGLVT--VYVNGGKARIRGVEL 493
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 600 SADKTFNNGINLHAALAYAYGRNEE-----TTQRLRSVAPFKAIVGGGWS--NETFGFDLSSTLSAGMLTDhlntpvTNT 672
Cdd:cd01347  494 EASYDLTDGLGLTGSYTYTDTEVKRtdgatTGNRLPGIPKHTANLGLDYElpDEGLTAGGGVRYRGKQYAD------TAN 567
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 516735075 673 ADTTFDAPGYAIVDLTGWWTPDQvpGLRVQAGVYNIFDQEYFNALAVRDVNLIStasqprdwYSEPGRTFKVSLTKTF 750
Cdd:cd01347  568 GNNTVKVPGYTLVDLSASYQFTK--NLTLRLGVNNLFDKDYYTSLSVRGSGLYG--------YYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
243-747 1.02e-55

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 198.46  E-value: 1.02e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  243 RYRTESDPADFDQHNLLFKLRQEFEGGHRLGLTAERFRRDLQTDKRDLQGTGRTYMIDnydarelnDRDRVSLDYDYEAT 322
Cdd:pfam00593   1 GWQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDT--------DRKRLSLGYDYDLG 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  323 SSDAFFTSARAVLYWQDLKKESGTNGRTAANVAYGRTNEIENKTWGFNGTVTKDFEYSNvRHSVKATLEATTSDWTQYSS 402
Cdd:pfam00593  73 DGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSH-DLLLGVELRTAGLDYRRLDD 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  403 AlcPTPTTCPSLNNQSEVPDVESKTIGLSIEDKIEFGDtNFALTPGIRFDWFSYDPSTSGGFASNpalakfgtlSDRSDQ 482
Cdd:pfam00593 152 D--AYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTD-RLTLTLGLRYDHYSTDGDDGNGGGDN---------FSRSYS 219
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  483 HVSPKVLATYELTPDVQLYTQLSSAFRAPTVDELYSRFYNAGGNYAQLGNPDLKPETGYGVEMGANFDTGDFNGRLAVFH 562
Cdd:pfam00593 220 AFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFY 299
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  563 NRYHNFIETVTSVNATTGITeFNYTNVSSVTISGIEASADKTFNNGINLHAALAYAYGRNEETT----QRLRSVAPFKAI 638
Cdd:pfam00593 300 IDIKNLITSDPDGPGLGGTV-YTYTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADAddtgNPLPNVPRHTAN 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  639 VGGGWSNETFGFdlssTLSAGMLTDHLNTPVTNTADTTFDAPGYAIVDLTGWWTPDqvPGLRVQAGVYNIFDQEYFNAla 718
Cdd:pfam00593 379 LGLTYDFPLGGW----GARLGARYVGSGERRYGDAANTFKTPGYTLVDLSAGYRLN--KNLTLRLGVNNLFDKYYKRY-- 450
                         490       500
                  ....*....|....*....|....*....
gi 516735075  719 vrdvnlISTASQPRDWYSEPGRTFKVSLT 747
Cdd:pfam00593 451 ------YSSGGGNLGGYPGPGRTFYLGLS 473
PRK13483 PRK13483
ligand-gated channel protein;
1-712 4.06e-25

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 111.02  E-value: 4.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   1 MIVRHWRSVLLVCTAATVvlPVSQSFAQSAtaatpqataEDSTvLQKIVVkgkrAAPGS---VADTPVSTE-ITDKKLDE 76
Cdd:PRK13483   1 MKKYLAQVISALCLLPAV--FVTHALAQAA---------PDKT-METVVV----TASGYeqqIRDAPASISvITREDLEN 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  77 KQVTNIEDLGRSVdPGINASRGD--AGINLRGLSGPRILTIVDGipipyLSNSSRQgafAPANANG----GGDTFDFNSL 150
Cdd:PRK13483  65 RFYRDLTDALLDV-PGVVVTGGGdrTDISLRGMGSQYTLILVDG-----KRQSSRE---TRPNSDGpgveQAWTPPLAAI 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 151 SSLDIVRGADSSRGGSGMLGGAIVVNTLEpedlipVGRDWGAIVKSTYDSEDRSISGSAAAAKKIGNTSIL-------FQ 223
Cdd:PRK13483 136 ERIEVIRGPMSSLYGSDAIGGVINIITRK------VPNEWQGEVRLDTTLQENSDSGNVYQANFFVNGPLIkdllglqLY 209
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 224 GGYRKGHERDNMGdsdSYGRYRTESDPADF-----DQHNLLFKL---RQEFEGghRLGLTAERFRRDLQTDKRDL-QGTG 294
Cdd:PRK13483 210 GQYTQREEDDIEG---GYRDKDARSLTAKLaltpnEDHDIMLEVgtsNQERDS--TVGKTVAPLAPGESCGRRGCpESST 284
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 295 RTYmidnydarelnDRDRVSLDY--DYEATSSDAFftsaravlywqdLKKESGTNGRTAANVaygrTNEIENKTW----G 368
Cdd:PRK13483 285 TEY-----------ERSTVSLSHtgRWDFGTSDTY------------IQHEEFDNKSREMKI----KNTDFQSSLvaplG 337
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 369 FNGTVTKDFEYSnvrhsvKATLEATTSdwtqyssalcptpttcpslNNQSEVPDVESKTIGLSIEDKIEFGDtNFALTPG 448
Cdd:PRK13483 338 QEHTLTFGAAYN------HQDLTDETS-------------------NQISDLTDISRTQWAVFSEDEWRIAD-DFALTGG 391
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 449 IRFDwfsyDPSTSGGfasnpalakfgtlsdrsdqHVSPKVLATYELTPDVQLYTQLSSAFRAPTVDEL------YSRfyn 522
Cdd:PRK13483 392 LRLD----HDENFGG-------------------HVSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQTtpdwgqVSR--- 445
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 523 aGGNYaqLGNPDLKPETGYGVEMGANFDTGD-FNGRLAVFHNRYHNFIETVT--SVNATTGITEFN-----YTNVSSVTI 594
Cdd:PRK13483 446 -GGNI--YGNPDLKPETSLNKELGLYYDLGSgLTASLTVFYNEFKDKITRVAcpATQCTDGPNQFGadpttYVNIDEAVT 522
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 595 SGIEASADKTFNNGINLHAalAYAYGRNEETTqrlrsvAPFKaivgGGWSNETFGFDLSSTLSAgMLTDHLNT------- 667
Cdd:PRK13483 523 QGVEASLSYPITSTLSLSG--NYTYTDSEQKS------GAYK----GSPLNQLPKHLFQASLNW-EPTDRLNSwarvnyr 589
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|
gi 516735075 668 -----PVTNTADTTFDAPGYAIVDLTGWWTPDQvpGLRVQAGVYNIFDQE 712
Cdd:PRK13483 590 geesqPTTGPSSSSFIAPSYTFLDLGANYQLTD--NLKLSAGIYNLFDKE 637
 
Name Accession Description Interval E-value
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
46-750 3.57e-116

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 366.74  E-value: 3.57e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   46 QKIVVKGKRAAPGSVAD---TPVSTE-ITDKKLDEKQVTNIEDLGRSVdPGINASRG----DAGINLRGLSGPRILTIVD 117
Cdd:TIGR01786   1 DTITVTATRTADPQRRDlsvTPASVSvISREQLKSQQVRNLRDLLRYE-PGVSVVEGgrggSQGINIRGLDKNRVAVLVD 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  118 GIPIPYlSNSSRQGAFAPANangggdTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDLIPVGRDWGAIVKST 197
Cdd:TIGR01786  80 GIRQNT-SYGGQGSTFYAIN------SIDPELIKSIEIVKGASSSLYGSGALGGVVAFRTKDAADLLKPGKDLGGLSKLG 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  198 YDSEDRSISGSAAAAKKIGNTSILFQGGYRKGHE-RDNMGDSDSYGRYRTESDPADFDQHNLLFKLRQEFEGGHRLGLTA 276
Cdd:TIGR01786 153 YSSANNRFTQSVAAAGRNDDVDALVQATYRRGHElKNGNKANIGNESKRSKPNPSDYKSQSFLAKLGWQLNDAHRLGLSL 232
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  277 ERFRRDLQTDK--RDLQGTGRTYMIDNYDARELNDRD----RVSLDYDYeaTSSDAFFTSARAVLYWQDLK---KESGTN 347
Cdd:TIGR01786 233 EYTQTDYDEPEmtNTSYLTKPLGAPLLSSTVVLGDSKtrdrRTGLDYEL--NPDNSWLDTVKLALDKQYIQlynYLNATS 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  348 GRTAANVAYGRTNeiENKTWGFNGTVTKDF--EYSNVRHSVKATLEATTSDwTQYSSALCPTPTTCPSLN-NQSEVPDVE 424
Cdd:TIGR01786 311 ASDYPGVDKNGRY--KDKYDYYTLGFDTNNkiEFSVHSLSLTYGLDRFKDK-VSTGDSRRNLPTAAYNLYgYEGENRPVK 387
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  425 SKTIGLSIEDKIEFGDtNFALTPGIRFDWFSYDPSTSGGFASNPalakfgtlSDRSDQHVSPKVLATYELTPDVQLYTQL 504
Cdd:TIGR01786 388 GSNFGLFLQDNIKLGD-WLSLSAGLRYDHYKTDPKADESKDYGA--------ISKTYSRWSPSLGLTYKPTPWLTLYYSY 458
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  505 SSAFRAPTVDELYSRFYNAGG-NYAQLGNPDLKPETGYGVEMGANFDTGDFNGRLAVFHNRYHNFIETV------TSVNA 577
Cdd:TIGR01786 459 SQGFRAPSFDELYGTGAHPGGgPYTFLPNPNLKPETSKNWEIGINLHFDQLDFKVSYFRNDYKDFIDLGigvtakGNMAQ 538
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  578 TTGITEFNYTNVSSVTISGIEASA----DKTFNNGINLHAALAYAY--GRNEETTQRLRSVAPFKAIVGGGW--SNETFG 649
Cdd:TIGR01786 539 VGSNTITNYVNIDNARIRGIELSGrydlGSFFSGPDGWTTTLKYGYtkGKDSDTNPWLNAITPLKVVLGLGYdhPDEKWG 618
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  650 FDLSSTLSAGMLTDHLNTPVTNTADT----TFDAPGYAIVDLTGWWTPdqVPGLRVQAGVYNIFDQEYFNALAVRDVNLI 725
Cdd:TIGR01786 619 VGLTLTFSGAKDAVDAYATYYENGEAakagPLRTPSYTVVDLYGYYKP--NKNLTLRFGVYNLLDRKYTTWESARQAGPL 696
                         730       740
                  ....*....|....*....|....*
gi 516735075  726 STasqprdWYSEPGRTFKVSLTKTF 750
Cdd:TIGR01786 697 AT------GYTAPGRNYKASVEYKF 715
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
45-750 2.08e-104

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 334.36  E-value: 2.08e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   45 LQKIVVKGKRAaPGSVADTPVSTE-ITDKKLDEKQVTNIEDLGRSVdPGINAS-RGDAG---INLRGLSGPRILTIVDGI 119
Cdd:TIGR01785   1 LDTVTVTATRT-RQVLSEAPASVSvISGEQIESKQANNLADALNTV-PGVDVTgGGRPPgqsINIRGLQDNRVLVVVDGA 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  120 PIPYLSNSSRQGAFapanangggdTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDLIPVGRDWGAIVKSTYD 199
Cdd:TIGR01785  79 RQNYQRGGAHNGSL----------FVDPELLKRIEIVKGPSSSLYGSGALGGVVAFRTKDAADLLRPGQLFGGLAKLSYG 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  200 SEDRSISGSAAAAKKIG-NTSILFQGGYRKGHERDNMGDSDSYgryrtesdPADFDQHNLLFKLRQEFEGGHRLGLTAer 278
Cdd:TIGR01785 149 SNNNSFGGSVAVAGRLDdNLDALVAATYRDGGNYRNGNKEEAT--------NSAYVQKNLLAKLGWQLDDAQRLEFSY-- 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  279 FRRDLQTDKRDLQGTGRTYMIDNYDARELNDRDRVSLDYDYEATSSDAFFTSARAVLYWQDLKKESGTNGRTaanvaYGR 358
Cdd:TIGR01785 219 FTTEGSLDEAQNSGPGTEYVLGSSSTLLASSTRDRSATLTYNWTPEDNPWLDATASLYYNRTENDNDRSARG-----VGR 293
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  359 TNEIENKTWGFNGTVTKDFEYSNVRHSVKAtLEATTSDWTQYSSalcpTPTTCPSLNnqSEVPDVESKTIGLSIEDKIEF 438
Cdd:TIGR01785 294 EEGYQYTTYGATLQNTSRFDVASWSTLTYG-VDWMKDKRRTESF----DPNSVTTIV--PNPPSAKEYFFGLFLQDNIPL 366
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  439 GDTNFALTPGIRFDWFSYDPSTSGGFASnpalakfgtlSDRSDQHVSPKVLATYELTPDVQLYTQLSSAFRAPTVDELYS 518
Cdd:TIGR01785 367 LDDRLTLSAGLRYDHYKLSPKTTADTEA----------VDRSYSRWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELYG 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  519 RFYNAGGN--YAQLGNPDLKPETGYGVEMGAN-------FDTGDFNGRLAVFHNRYHNFIETVTSV--NATTGITEF-NY 586
Cdd:TIGR01785 437 TGDHPGTPggYTFAPNPNLKPETSKTWELGANlsfdnllLDNDQLQFKVAYFYNDVKDFIDLTIGVtdNVTAGMNNItQY 516
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  587 TNVSSVTISGIEASADKTFNNgINLHAALAYAYGRNEETTQRLRSVAPFKAIVGGGWSNETFGFDLSSTLSAGMLTDHLN 666
Cdd:TIGR01785 517 VNIDGARIRGIEASASYDAGL-WATGLSYGYTIGKDQNTNQWLSNIPPLKLVVTVGYRFPDRRLDLGAKAAYYERQSESP 595
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  667 TPVTNTADTTFDAPGYAIVDLTGWWTPDQVPGLRVQAGVYNIFDQEYFNALAVRdvnlistasqprdwYSEPGRTFKVSL 746
Cdd:TIGR01785 596 TTEDVAANGLLTTPGYTVVDLYATYQPNAVKGLTVRFGVNNLTDRKYTPAQSVP--------------GAGPGRNFKGSV 661

                  ....
gi 516735075  747 TKTF 750
Cdd:TIGR01785 662 KYQF 665
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
45-723 2.50e-86

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 285.95  E-value: 2.50e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  45 LQKIVVKGKRAApGSVADTPVS-TEITDKKLDEKQVTNIEDLGRSVdPGINASR---GDAGINLRGLSG--PRILTIVDG 118
Cdd:COG1629    1 LEEVVVTATRTD-ESLQDVPGSvSVISREQLEDQPATDLGDLLRRV-PGVSVTSaggGAGQISIRGFGGggNRVLVLVDG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 119 IPIPYlsnssrqgafaPANANGGGDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDlipvgrDWGAIVKSTY 198
Cdd:COG1629   79 VPLND-----------PSGGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKD------GKGGEVSASY 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 199 DSEDRsISGSAAAAKKIGNTSILFQGGYRkgherdnmgDSDSYGryrtesDPADFDQHNLLFKLRQEFEGGHRLGLTAER 278
Cdd:COG1629  142 GSYGT-YRASLSLSGGNGKLAYRLSASYR---------DSDGYR------DNSDSDRYNLRAKLGYQLGDDTRLTLSASY 205
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 279 FRRDLQTD----KRDLQGTGRTYMIDN--YDARELNDRDRVSLDYDYEATSSDAFFtsaRAVLYWQ-DLKKESGTNGRTA 351
Cdd:COG1629  206 SDSDQDSPgyltLAALRPRGAMDDGTNpySNDTDDNTRDRYSLSLEYEHLGDGLKL---SASAYYRyDDTDLDSDFTPTP 282
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 352 ANVAYGRTNEIENKTWGFNGTVTKDFEYsNVRHSVKATLEATTSDWTQYSSALCPTPTTCPSLNNQSEVpDVESKTIGLS 431
Cdd:COG1629  283 ADGGTLEQTDFDNRTYGLELRLTYDLGF-GGKHTLLVGLDYQRQDLDGSGYPLDLGSGSLPTLTSGADD-DGTTTSLALY 360
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 432 IEDKIEFGDtNFALTPGIRFDWFSYDPStsggfasNPALAKFGTLSDRSDQHVSPKVLATYELTPDVQLYTQLSSAFRAP 511
Cdd:COG1629  361 AQDTYKLTD-KLTLTAGLRYDYVSYDVD-------DTVTGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAP 432
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 512 TVDELYSRfynaGGNYAQLGNPDLKPETGYGVEMGA--NFDTGDFNGRLAVFHNRYHNFIETVTSVNATTGITefNYTNV 589
Cdd:COG1629  433 TFGELYAN----GTDPYSVGNPDLKPETSTNYELGLryRLLDGRLSLSLALFYSDVDNEILSVPLPNDSGFST--YYTNA 506
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 590 SSVTISGIEASADKTFNNGINLHAALAYAYGRNEETT--------QRLRSVAPFKAIVGGGWS-NETFGFDLSSTLSAGM 660
Cdd:COG1629  507 GKARSYGVELELSYQLTPGLSLNASYSYTDAKFDDDTdgsadldgNRLPGVPPLTANLGLTYEfPGGWSLGLGVRYVGDR 586
                        650       660       670       680       690       700
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516735075 661 LTDHLNTPVTNtadttfdaPGYAIVDLTGWWTPDqvPGLRVQAGVYNIFDQEYFNALAVRDVN 723
Cdd:COG1629  587 YLDDANTQGAP--------GGYTLVDLGAGYRFG--DNLTLSLGVDNLFDKKYATSLSVRASN 639
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
19-695 6.98e-79

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 265.18  E-value: 6.98e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  19 VLPVSQSFAQSATAATPQATAEDSTVLQKIVVKGKRAAPgSVADTPVSTE-ITDKKLDEKQVTNIEDLGRSVdPGINASR 97
Cdd:COG4771    1 LLLASLLLLLALAAQAADALAEDATELEEVVVTATRTEQ-SLSDAPASVSvITAEEIEKLGATDLADALRLL-PGVSVTR 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  98 -----GDAGINLRGLSGPRILTIVDGIPIPYLSNSSRqgafapananGGGDTFDFNSLSSLDIVRGADSSRGGSGMLGGA 172
Cdd:COG4771   79 sggrgGSSGISIRGLGGDRVLVLIDGVPVNNPALGGG----------GDLSYIPPDDIERIEVIRGPASALYGSDAIGGV 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 173 IVVNTLEPEDlipvgrDWGAIVKSTYDSEDR-SISGSAAAAKKIGNTSILFQGGYRKGHERDNMgdsdsygRYRTESDPA 251
Cdd:COG4771  149 INIITKKPTD------ELEGSVSLGYGSNGNgTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLDY-------RNGGFVGNS 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 252 DFDQHNLLFKLRQEFEGGHRLGLTAERFRRDLQTDKRDLqGTGRTYMIDNYDARELNDRDRVSLDYDYEatssdaFFTSA 331
Cdd:COG4771  216 GYERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTL-GDTEISSDNAGDRDTTTDRGNYSLRYNGD------LGDNL 288
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 332 RAVLYWQDLKKESGTNGRTAANVAYGRTneiENKTWGFNGTVTKDFeysNVRHSVKATLEATTSDWTQYSSalcptpttc 411
Cdd:COG4771  289 DLSLYYSRTDRDSTNGSLGGSTGSFSDS---DDTTYGLELDLTYPL---GGNHTLTLGAEYRYDDLDSSSF--------- 353
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 412 pslnnqSEVPDVESKTIGLSIEDKIEFGDtNFALTPGIRFDWFSYdpstsggfasnpalakfgtLSDRSDQHVSPKVLAT 491
Cdd:COG4771  354 ------LGGADASRDTYGLFAQDEWKLTD-KLTLTAGLRYDYYST-------------------FGASNYTAFSPRLGLR 407
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 492 YELTPDVQLYTQLSSAFRAPTVDELYSRFYNAGGNYAqLGNPDLKPETGYGVEMGA--NFDTGDFNGRLAVFHNRYHNFI 569
Cdd:COG4771  408 YDLSDNLTLRASYGRGFRAPSLAELYGSGTGTPGRYV-LGNPDLKPETSDNYELGLeyRLGNGGLSLSLTGFYTDIKDLI 486
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 570 ETVTSVNATTGIteFNYTNVSSVTISGIEASADKTFNNGINLHAALAYAYGRNE--ETTQRLRSVAPFKAIVGGGWSNET 647
Cdd:COG4771  487 VLVPVGPGPGDV--LQYENVGKARTYGLELELKYRLGKGLTLTASYTYLDSKIDdgDTGEPLPNVPPHKANLGLDYRLPK 564
                        650       660       670       680
                 ....*....|....*....|....*....|....*....|....*...
gi 516735075 648 FGFDLSSTLSAGMltdhlNTPVTNTADTTFDAPGYAIVDLTGWWTPDQ 695
Cdd:COG4771  565 WWLLLLLTRYYGG-----RYVTPPSGRLEGYTPGYTLLDLRASYKLTK 607
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
65-750 1.76e-71

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 245.44  E-value: 1.76e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  65 VSTEITDKKLDEKQVTNIEDLGRSVdPGINASRGDAG----INLRGLSGPRILTIVDGIPIpylsnssrqgAFAPANANG 140
Cdd:cd01347    1 SVSVITAEDIEKQPATSLADLLRRI-PGVSVTRGGGGggstISIRGFGPDRTLVLVDGLPL----------ASSNYGRGV 69
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 141 GGDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPedlipvGRDWGAIVKSTYDSEDRSISGS-----AAAAKKI 215
Cdd:cd01347   70 DLNTIPPELIERVEVLKGPSSALYGSGAIGGVVNIITKRP------TDEFGGSVTAGYGSDNSGSSGGggfdvSGALADD 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 216 GNTSILFQGGYRKGherdnmgdsDSYGRYRTESDPADFDQHNLLFKLRQEFEGGHRLGLTAERFRRDLQTDKRDLQGTGR 295
Cdd:cd01347  144 GAFGARLYGAYRDG---------DGTIDGDGQADDSDEERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGT 214
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 296 TYMI--------DNYDARELNDRDRVSLDYDYEATSSDAFFTSaRAVLYWQDLKKESGTNGRTAANVAYGRTNEIENKT- 366
Cdd:cd01347  215 GSSLgggpssntNGDRDWDYRDRYRKRASLGLEHDLNDTGWTL-RANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSs 293
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 367 ------WGFNGTVTKDFEYSNVRHSVKATLEATTSDWTQYSSALcptpttcpslnnqsevpdvesktiglSIEDKIEFGD 440
Cdd:cd01347  294 erdttqLGFDAGLNAPFGTGPVAHTLTLGVEYRREELDEKQTAL--------------------------YAQDTIELTD 347
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 441 tNFALTPGIRFDWFSYDPSTSGGFasnpalakfGTLSDRSDQHVSPKVLATYELTPDVQLYTQLSSAFRAPTVDELYSRF 520
Cdd:cd01347  348 -DLTLTLGLRYDHYDQDSKDTIAG---------GTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGG 417
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 521 YNAGGNYaqLGNPDLKPETGYGVEMGANFDTG-DFNGRLAVFHNRYHNFIETVTSVNATTGITefNYTNVSSVTISGIEA 599
Cdd:cd01347  418 SHGGTAA--VGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEIVSTPTNTGLGLVT--VYVNGGKARIRGVEL 493
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 600 SADKTFNNGINLHAALAYAYGRNEE-----TTQRLRSVAPFKAIVGGGWS--NETFGFDLSSTLSAGMLTDhlntpvTNT 672
Cdd:cd01347  494 EASYDLTDGLGLTGSYTYTDTEVKRtdgatTGNRLPGIPKHTANLGLDYElpDEGLTAGGGVRYRGKQYAD------TAN 567
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 516735075 673 ADTTFDAPGYAIVDLTGWWTPDQvpGLRVQAGVYNIFDQEYFNALAVRDVNLIStasqprdwYSEPGRTFKVSLTKTF 750
Cdd:cd01347  568 GNNTVKVPGYTLVDLSASYQFTK--NLTLRLGVNNLFDKDYYTSLSVRGSGLYG--------YYGPGRTYYLSVSYKF 635
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
40-735 1.71e-63

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 224.81  E-value: 1.71e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  40 EDSTVLQKIVVKGKRAAPGSVADTPVS-TEITDKKLDEKQVTNIEDLGRSVdPGINA-SRGDAG----INLRGLSG---P 110
Cdd:COG4772   18 EAATTLETVVVTGSRAAEARLKDVPGSvSVVDREELENQAATSLREVLRRV-PGVNVqEEDGFGlrpnIGIRGLGPrrsR 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 111 RILTIVDGIPIpylsnssrqgAFAPANANGGGDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDlipvgrDW 190
Cdd:COG4772   97 GITLLEDGIPI----------APAPYGDPAAYYFPDLERMERIEVLRGAAALRYGPQTVGGAINFVTRTIPT------AF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 191 GAIVKSTYDSEDrSISGSAAAAKKIGNTSILFQGGYRKGH-ERDNmgdsdsygryrtesdpADFDQHNLLFKLRQEFEGG 269
Cdd:COG4772  161 GGELRVTGGSFG-YRRTHASVGGTVGNFGYLVEYSRKRGDgFRDN----------------SGFDINDFNAKLGYRLSDR 223
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 270 HRL---------------GLTAERFRRD-LQTDKRDLQGTGRTYMIDNYDARELNDRDRVSLDYDYEATSSDAFFTSARA 333
Cdd:COG4772  224 QELtlkfqyydedantpgGLTDAQFDADpRQSYRPADQFDTRRTQLSLRYEHQLSDNTTLTTTAYYNDFSRNWYIRQNTA 303
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 334 vlywqdlkkesgtngRTAANVAYGRTNEIENKTWGFNGTVTKDFEYSNVRH--SVKATLEATTSDWTQYSSALCPTPTTC 411
Cdd:COG4772  304 ---------------DPNTPGLGLRGNPRGYRSYGIEPRLTHRFELGGVPHtlEVGLRYHREEEDRKQYVNTYGQGRSGA 368
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 412 PSLNNQSEvpdvESKTIGLSIEDKIEFGDtNFALTPGIRFDWFSYDPSTSGGFASNPALAkfgtlSDRSDQHVSPKVLAT 491
Cdd:COG4772  369 GLRRDRRF----SADALAAYAQNRFELTG-RLTLTPGLRYEHIRRDRTDRYSTRTGGDDS-----GSNSYSEFLPGLGLL 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 492 YELTPDVQLYTQLSSAFRAPTVDELysrfynaggNYAQLGNPDLKPETGYGVEMGANFDTGD-FNGRLAVFHNRYHNFIE 570
Cdd:COG4772  439 YQLTDNLQLYANVSRGFEPPTFGDL---------AYGNGGNPDLKPEKSWNYELGTRGRIGNgLSAEVALFYIDYDNELG 509
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 571 TVTSVNATTGItefnYTNVSSVTISGIEASADKTF----NNGINLHAALAYAYGRNEETT------QRLRSVAPFKAIVG 640
Cdd:COG4772  510 SCSAAGGDRST----FTNAGETRHQGLELALDYDLlkggGLGLPLFAAYTYTDAEFTSDFgpvfagNRLPYVPRHQLTAG 585
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 641 GGWSNETFGFDLSSTLSAGMLTDHLNTPVTNTADTtfdAPGYAIVDLTGWWtpDQVPGLRVQAGVYNIFDQEYFNALAVR 720
Cdd:COG4772  586 LGYEHGGWTANLNGRYVSEQFTDAANTVADGSFGK---IPSYTVLDLSASY--DFGKNLSLFAGVNNLFDKRYIASRAPN 660
                        730
                 ....*....|....*
gi 516735075 721 DVNLIsTASQPRDWY 735
Cdd:COG4772  661 YAAGI-RPGPPRTVY 674
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
243-747 1.02e-55

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 198.46  E-value: 1.02e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  243 RYRTESDPADFDQHNLLFKLRQEFEGGHRLGLTAERFRRDLQTDKRDLQGTGRTYMIDnydarelnDRDRVSLDYDYEAT 322
Cdd:pfam00593   1 GWQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDT--------DRKRLSLGYDYDLG 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  323 SSDAFFTSARAVLYWQDLKKESGTNGRTAANVAYGRTNEIENKTWGFNGTVTKDFEYSNvRHSVKATLEATTSDWTQYSS 402
Cdd:pfam00593  73 DGLSWLSTLRLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSH-DLLLGVELRTAGLDYRRLDD 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  403 AlcPTPTTCPSLNNQSEVPDVESKTIGLSIEDKIEFGDtNFALTPGIRFDWFSYDPSTSGGFASNpalakfgtlSDRSDQ 482
Cdd:pfam00593 152 D--AYDPYDPANPSSSSYSDTTTDSYGLYLQDNIKLTD-RLTLTLGLRYDHYSTDGDDGNGGGDN---------FSRSYS 219
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  483 HVSPKVLATYELTPDVQLYTQLSSAFRAPTVDELYSRFYNAGGNYAQLGNPDLKPETGYGVEMGANFDTGDFNGRLAVFH 562
Cdd:pfam00593 220 AFSPRLGLVYKPTDNLSLYASYSRGFRAPSLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLKYDDGRLSLSLALFY 299
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  563 NRYHNFIETVTSVNATTGITeFNYTNVSSVTISGIEASADKTFNNGINLHAALAYAYGRNEETT----QRLRSVAPFKAI 638
Cdd:pfam00593 300 IDIKNLITSDPDGPGLGGTV-YTYTNVGKARIRGVELELSGRLWGLGLSGGGYTYTDADDDADAddtgNPLPNVPRHTAN 378
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  639 VGGGWSNETFGFdlssTLSAGMLTDHLNTPVTNTADTTFDAPGYAIVDLTGWWTPDqvPGLRVQAGVYNIFDQEYFNAla 718
Cdd:pfam00593 379 LGLTYDFPLGGW----GARLGARYVGSGERRYGDAANTFKTPGYTLVDLSAGYRLN--KNLTLRLGVNNLFDKYYKRY-- 450
                         490       500
                  ....*....|....*....|....*....
gi 516735075  719 vrdvnlISTASQPRDWYSEPGRTFKVSLT 747
Cdd:pfam00593 451 ------YSSGGGNLGGYPGPGRTFYLGLS 473
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
59-750 9.07e-36

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 143.86  E-value: 9.07e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  59 SVADTPVS-TEITDKKLDEKQVTNIEDLGRSVdPGINASRGDAG----INLRGLSGpRILTIVDGIPIPylsnssrqgaf 133
Cdd:COG4774    5 PLLDTPQSvTVVTRELIEDQGATSLADALRNV-PGVTFGAGEGGngdsFSIRGFSA-SGDIYVDGLRDP----------- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 134 apanangGGDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDlipvgrDWGAIVKSTYDSEDRsISGSAAAAK 213
Cdd:COG4774   72 -------GQYRRDTFNLERVEVLKGPASVLYGRGSPGGVINLVTKRPTD------EPFTEVTLTYGSDGQ-RRATLDVNG 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 214 KIG-NTSILFQGGYRKGH-ERDNmGDSDSYGRYrtesdPAdfdqhnLLFKLRQEFegghRLGLTAERFRRDLQTDkRDL- 290
Cdd:COG4774  138 PLGdDLAYRLNGMYRDSDsYRDG-VDNDRWGIA-----PS------LTWRLGDRT----RLTLDYEYQDDDRTPD-YGVp 200
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 291 -QGTGRTYMID---NY---DARELNDRDRVSLDYDYEATSSdaffTSARAVLYWQDLKKESGTNGRTAANVA-----YGR 358
Cdd:COG4774  201 aVANGRPVDVDrstFYgqpDDYSDSETDSATLRLEHDFNDN----WTLRNALRYSDYDRDYRNTYPTGGNATgtvtrSAY 276
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 359 TNEIENKTWGFNGTVTKDFEYSNVRHSVKATLEATTSDWTQYSSALCPTPTTCPSLNNQSEVP-----------DVESKT 427
Cdd:COG4774  277 RRDQDNDTLSNQTDLTGKFDTGGVKHTLLAGVEYSREDSDNARYSGGGTAPTVNLYNPVYGAPvtgptlggadnDSRTDT 356
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 428 IGLSIEDKIEFGDtNFALTPGIRFDWFSYDPSTSGGFASNpalakfgtlSDRSDQHVSPKVLATYELTPDVQLYTQLSSA 507
Cdd:COG4774  357 TGLYLQDTISLTD-RWSLLAGLRYDRFDTDYTDRTTGATT---------SSYDDSAFSPRAGLVYKPTPNLSLYASYSTS 426
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 508 FRAPTVDELYSRFynaggnyaqlgNPDLKPETGYGVEMGA--NFDTGDFNGRLAVFHNryhnfieTVTSVNATTGITEFN 585
Cdd:COG4774  427 FNPGGGAPSLSNA-----------GQALDPEKSRQYEVGVkwDLLDGRLSLTAALFRI-------EKTNVRTTDPANPGV 488
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 586 YTNVSSVTISGIEASADKTFNNGINLHAALAYAYGRNEETT------QRLRSVAPFKAIVGGGWSNETFGFdlssTLSAG 659
Cdd:COG4774  489 YVQTGEQRSRGVELEATGELTPGWSVLAGYTYLDAEITKSAnaanvgNRLPNVPRHSASLWTTYDLPLPGL----TLGGG 564
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 660 MltdHLNTPVTNTADTTFDAPGYAIVDLTGWWTPDqvPGLRVQAGVYNIFDQEYFnalavrdvnliSTASQPRDWYSEPG 739
Cdd:COG4774  565 V---RYVGSRYADAANTVKLPSYTRFDAGASYRLN--KNLTLRLNVNNLTDKRYY-----------ASAYGSGYVTPGAP 628
                        730
                 ....*....|.
gi 516735075 740 RTFKVSLTKTF 750
Cdd:COG4774  629 RTVLLSASYRF 639
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
7-750 3.87e-33

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 136.18  E-value: 3.87e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   7 RSVLLVCTAATVVLPVSQSFAQSATAatpqataEDSTVLQKIVVKGKRAAPGSVA---------------DTPVS-TEIT 70
Cdd:COG4773    1 AAALLAGSGLAAAAAGALAQAAAAAA-------AEATTLPEVTVTGTAEGTGGYTakssstatkldtplrETPQSvSVVT 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  71 DKKLDEKQVTNIEDLGRSVdPGINASRGDAG----INLRGLSGPRILtiVDGIPIpylsNSSRQGAFAPANangggdtfd 146
Cdd:COG4773   74 RQLIEDQGATTLDDALRNV-PGVTVSSYDGGgrdsFSIRGFSIDNYL--RDGLPL----GGFGGGQPDTAN--------- 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 147 fnsLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDlipvgrDWGAIVKSTYDSEDRS-----ISGSAAAAKKIG---Nt 218
Cdd:COG4773  138 ---LERVEVLKGPAGLLYGAGSPGGLVNLVTKRPTA------EPQGEVSLSAGSWDTYratadVGGPLNEDGTLRyrlN- 207
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 219 silfqGGYRkgherdnmgDSDSYgRYRTESD-----PAdfdqhnLLFKLRqefeGGHRLGLTAERFRRDLQTDKRDLQGT 293
Cdd:COG4773  208 -----AAYE---------DGDSF-RDGVDNRrtliaPS------LDWDLT----DDTTLTLGAEYQDDDSTGDRGFLPLD 262
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 294 GRTYMID---NYDAR-ELNDRDRVSLDYDYEATSSDAFftSARAVLYWQDLKKESGTNGRTAANVA-------YGRTNEI 362
Cdd:COG4773  263 GTLLDLPrstNLGEPwDYYDTETTTLFAELEHRFNDDW--SLRANARYSDSDRDGRSAYAYGAPDAatgtltrYASARDG 340
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 363 ENKTWGFNGTVTKDFEYSNVRHSVKATLEATTSDWTQYSSALCPTPTTCPSLNNQSEVP------DVESKTIGLSIEDKI 436
Cdd:COG4773  341 DSRSDSLDANLNGKFETGGLEHTLLVGADYSRYDSDSDSATAGTINIYNPVYGNLPEPDfdasdtDTTTRQTGLYAQDQI 420
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 437 EFGDtNFALTPGIRFDWFSYDPSTSGGfasnpalakfGTLSDRSDQHVSPKVLATYELTPDVQLYTQlssafraptvdel 516
Cdd:COG4773  421 SLTD-RLSLLLGGRYDWYETDSTNRLG----------GSTTSYDDSAFTPRAGLVYDLTPGLSLYAS------------- 476
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 517 YSRFYNAGGNYAQLGNPdLKPETGYGVEMG--ANFDTGDFNGRLAVFHnryhnfIeTVTSVNATTGITEFNYTNVSSVTI 594
Cdd:COG4773  477 YSESFEPQSGADNNGNP-LDPETGKQYEAGvkGELFDGRLNATLAVFD------I-TQKNVATTDPDNPNFYVQVGEVRS 548
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 595 SGIEASADKTFNNGINLHAALAYAYGRNEETT-----QRLRSVAPFkaiVGGGWSNETFGFDLSS--TLSAGMltdHLNT 667
Cdd:COG4773  549 RGVELELSGELTPGLNLIAGYTYTDAKITKDAdalegKRLTNVPRH---TASLWTTYRFPSGALKglGLGGGV---RYVG 622
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 668 PVTNTADTTFDAPGYAIVDLTGWWTPDqvPGLRVQAGVYNIFDQEYFNALAVRDVNlistasqprdWYSEPgRTFKVSLT 747
Cdd:COG4773  623 ERYGDAANTFTLPSYTLVDAGARYDLG--KNWTLQLNVNNLFDKKYYASSGSRGYV----------YYGAP-RNVRLSLS 689

                 ...
gi 516735075 748 KTF 750
Cdd:COG4773  690 YKF 692
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
62-750 4.98e-31

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 129.45  E-value: 4.98e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   62 DTPVSTE-ITDKKLDEKQVTNIEDLGRSVDPGINASRGDAG----INLRGLSG-PRILTI-VDGIPIPYLSNSSRQgafA 134
Cdd:TIGR01783   1 DIPQSVSvITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTqfgnITIRGFGLeVDIDNVyLDGVPLLSRGNLAIV---D 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  135 PANangggdtfdfnsLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDLiPVGR-DWGAIVKSTYDSEDRsISGSAAAAk 213
Cdd:TIGR01783  78 PAM------------VERVEVLRGPASLLYGGSAPGGVINIVTKRPQDE-PKGSvTFGAGTRSGYRTAFD-LGGPLGAD- 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  214 kiGNTSILFQGGYRKGherDNMGDSDSYGRY----RTESDPADFDQHNLLFKLRQEFEGGHRLGLTAER--FRRDLQTDK 287
Cdd:TIGR01783 143 --GTFRGRLNGARQDG---DSFYDGAGEETRlgatATDWQLDDRTLLRLGAYYQKERDRGGYGGLPASGgtSGRDLSSDR 217
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  288 rdLQGTGRTYMIDNYDARELNDR--DRVSLDYDYEATSSDAFFTSARAVLYWQDLKKESGTNGRTAANVAYGRTNEIEnk 365
Cdd:TIGR01783 218 --YLGTSSNRNYDDREYLSYGLSleYQFNDVWTGKQNLRYSYFDTDSNQVQASGYSSDGGLFGRSLTVVNVKQDRVQI-- 293
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  366 TWGFNGtvtkDFEYSNVRHSV---KATLEATTSDWTQYSS------ALCPTPTTCPSLNNQSEVPDVESKTIGLSI--ED 434
Cdd:TIGR01783 294 DAGLDG----EFETGPIEHDLllgVSYGQRTTNRFNNTGYpsdniySLTATSSARTDIGDSPKDRALSSTTKALNGvaLQ 369
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  435 KIEFGDtNFALTPGIRFDWFSYDpstsggfaSNPALAKFGTlsDRSDQHVSPKVLATYELTPDVQLYTQLSSAFRAPtvd 514
Cdd:TIGR01783 370 RILLAD-KWTLTLGGRYDSVDVK--------SNNGVAGSTG--KRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPG--- 435
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  515 ELYSRFYNAGGNyaqlgnpDLKPETGYGVEMGANFDTGD-FNGRLAVFHNRYHNFIeTVTSVNATtgitefNYTNVSSVT 593
Cdd:TIGR01783 436 GYYPKGAGNSGD-------ILEPEKGKNYELGVRYDLGDsLLATAALFRITKDNQL-VQDPVNGT------FSVNAGKTR 501
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  594 ISGIEASADKTFNNGINLHAALAYAYGRNEETTQ------RLRSVAPFKAIVGGGWSNETFGFDLSSTLSAGMLTDHlnt 667
Cdd:TIGR01783 502 NRGVELEARGYLTPGLSLSAGYTYTDAEFTEDTNgdtqgnTVPFVPKHTASLWASYAPPVGDNGLTLGGGVQYTGKA--- 578
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  668 pvTNTADTTFDAPGYAIVDLTGWWTPDQVPGLRVQAGVYNIFDQEYFnalavrdvnlISTASQPRDW--YSEPGRTFKVS 745
Cdd:TIGR01783 579 --YVDGGNTGKVPSYTVVDLSVRYDLTKKKNLTLALNVNNLFDRDYY----------TSGYRWGPSAyiYPGAPRTVGLS 646

                  ....*
gi 516735075  746 LTKTF 750
Cdd:TIGR01783 647 VSYDF 651
PRK13483 PRK13483
ligand-gated channel protein;
1-712 4.06e-25

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 111.02  E-value: 4.06e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   1 MIVRHWRSVLLVCTAATVvlPVSQSFAQSAtaatpqataEDSTvLQKIVVkgkrAAPGS---VADTPVSTE-ITDKKLDE 76
Cdd:PRK13483   1 MKKYLAQVISALCLLPAV--FVTHALAQAA---------PDKT-METVVV----TASGYeqqIRDAPASISvITREDLEN 64
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  77 KQVTNIEDLGRSVdPGINASRGD--AGINLRGLSGPRILTIVDGipipyLSNSSRQgafAPANANG----GGDTFDFNSL 150
Cdd:PRK13483  65 RFYRDLTDALLDV-PGVVVTGGGdrTDISLRGMGSQYTLILVDG-----KRQSSRE---TRPNSDGpgveQAWTPPLAAI 135
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 151 SSLDIVRGADSSRGGSGMLGGAIVVNTLEpedlipVGRDWGAIVKSTYDSEDRSISGSAAAAKKIGNTSIL-------FQ 223
Cdd:PRK13483 136 ERIEVIRGPMSSLYGSDAIGGVINIITRK------VPNEWQGEVRLDTTLQENSDSGNVYQANFFVNGPLIkdllglqLY 209
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 224 GGYRKGHERDNMGdsdSYGRYRTESDPADF-----DQHNLLFKL---RQEFEGghRLGLTAERFRRDLQTDKRDL-QGTG 294
Cdd:PRK13483 210 GQYTQREEDDIEG---GYRDKDARSLTAKLaltpnEDHDIMLEVgtsNQERDS--TVGKTVAPLAPGESCGRRGCpESST 284
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 295 RTYmidnydarelnDRDRVSLDY--DYEATSSDAFftsaravlywqdLKKESGTNGRTAANVaygrTNEIENKTW----G 368
Cdd:PRK13483 285 TEY-----------ERSTVSLSHtgRWDFGTSDTY------------IQHEEFDNKSREMKI----KNTDFQSSLvaplG 337
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 369 FNGTVTKDFEYSnvrhsvKATLEATTSdwtqyssalcptpttcpslNNQSEVPDVESKTIGLSIEDKIEFGDtNFALTPG 448
Cdd:PRK13483 338 QEHTLTFGAAYN------HQDLTDETS-------------------NQISDLTDISRTQWAVFSEDEWRIAD-DFALTGG 391
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 449 IRFDwfsyDPSTSGGfasnpalakfgtlsdrsdqHVSPKVLATYELTPDVQLYTQLSSAFRAPTVDEL------YSRfyn 522
Cdd:PRK13483 392 LRLD----HDENFGG-------------------HVSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQTtpdwgqVSR--- 445
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 523 aGGNYaqLGNPDLKPETGYGVEMGANFDTGD-FNGRLAVFHNRYHNFIETVT--SVNATTGITEFN-----YTNVSSVTI 594
Cdd:PRK13483 446 -GGNI--YGNPDLKPETSLNKELGLYYDLGSgLTASLTVFYNEFKDKITRVAcpATQCTDGPNQFGadpttYVNIDEAVT 522
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 595 SGIEASADKTFNNGINLHAalAYAYGRNEETTqrlrsvAPFKaivgGGWSNETFGFDLSSTLSAgMLTDHLNT------- 667
Cdd:PRK13483 523 QGVEASLSYPITSTLSLSG--NYTYTDSEQKS------GAYK----GSPLNQLPKHLFQASLNW-EPTDRLNSwarvnyr 589
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|
gi 516735075 668 -----PVTNTADTTFDAPGYAIVDLTGWWTPDQvpGLRVQAGVYNIFDQE 712
Cdd:PRK13483 590 geesqPTTGPSSSSFIAPSYTFLDLGANYQLTD--NLKLSAGIYNLFDKE 637
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
15-750 5.25e-25

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 110.89  E-value: 5.25e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  15 AATVVLPVSQSFAQSATAATPQATAEDSTVLQKIVVKGK---RAAPGsvadtpVSTeITDKKLDEKQVTN-IEDLGRSVd 90
Cdd:PRK13524   8 LALLVNLGIYGVAQAAEAEDAKTDDTPASHEDTIVVTAAeqnLQAPG------VST-ITAEDIRKRPPANdVSEIIRTM- 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  91 PGIN----ASRGDAG----INLRGLSGPRILTIVDGIPIPYlSNSSRQG-----------AFAPANAngggdtfdfnsLS 151
Cdd:PRK13524  80 PGVNltgnSTSGQRGnnrqIDIRGMGPENTLILIDGKPVSS-RNSVRYGwrgerdtrgdtNWVPPEM-----------IE 147
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 152 SLDIVRGADSSRGGSGMLGGaiVVNTLEPedliPVGRDWGAIVKSTYDSEDRSISGSAAaakkigNTSILFQGGyrkghe 231
Cdd:PRK13524 148 RIEVLRGPAAARYGNGAAGG--VVNIITK----KPTGEWHGSWNTYFNAPEHKAEGATK------RTNFSLSGP------ 209
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 232 rdnMGDSDSYGRY----RTESDPADFDQ-----------------------HNLLFKLRQEFEGGHRLGLTAERFRRD-L 283
Cdd:PRK13524 210 ---LGDELSFRLYgnlnKTQADAWDINQghqsartgsyagtlpagregvinKDINGLLRWDFAPLQSLELEAGYSRQGnL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 284 QTDkrDLQGTGRTYMIDNYDARELNDRDRVSLDYDYEATSSDAFFTSARAvlywqdlKKESGTNGRTAANVAYGRTNEIE 363
Cdd:PRK13524 287 YAG--DTQNTNSDALVKSLYGKETNRMYRQNYALTHRGGWDNGVSTSNYA-------QYEHTRNSRLPEGLAGGTEGIFN 357
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 364 NKTWGFngtvtKDFEYSNVR-HS---------VKATLEATTsDWTQ------YSSALCPTP-TTCPSLNNQSEVPDVESK 426
Cdd:PRK13524 358 EKATQF-----STIDLDDVMlHSevnlpfdllVNQTLTLGT-EWNQqrmkdpSSNTQALTSgGAIPGVSATGRSPYSKAE 431
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 427 TIGLSIEDKIEFGDTNFaLTPGIRFDwfsyDPSTSGgfaSNpalakfgtlsdrsdqhVSPKVLATYELTPDVQLYTQLSS 506
Cdd:PRK13524 432 IFSLFAEDNMELTDSTM-LTPGLRFD----HHSIVG---NN----------------WSPSLNLSQGLGDDFTLKMGIAR 487
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 507 AFRAPTVDE------LYSR---FYNAGGNYAQL-GNPDLKPETGYGVEMGANFDTGDFNGRLAVFHNRYHNFIE---TVT 573
Cdd:PRK13524 488 AYKAPNLYQtnpnyiLYSKgqgCYASAGNGCYLqGNDDLKAETSVNKEIGLEFKRDGWLAGLTWFRNDYRNKIEagyVPV 567
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 574 SVNATTGITEFNYTNVSSVTISGIEASADKTFNNGINLHAALAYAY-GRNEETTQRLrSVAPFKAIvgggwsNETFGFDL 652
Cdd:PRK13524 568 GTNSVGKTDIYQWENVPKAVVEGLEGTLNVPVSETVNWTNNLTYMLqSKNKTTGDPL-SIIPEYTL------NSTLSWQA 640
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 653 SSTLSA-GMLT----------DHLNTPVTNTAdtTFDAPGYAIVDLTGWWtpDQVPGLRVQAGVYNIFDQEYF---NALA 718
Cdd:PRK13524 641 TEDLSLqSTFTwygkqkpkkyNYKGQPVTGSA--TKEVSPYSIVGLSATY--DVTKNVSLTGGVDNLFDKRLWregNAQT 716
                        810       820       830
                 ....*....|....*....|....*....|..
gi 516735075 719 VRDVNLISTASQprdwYSEPGRTFKVSLTKTF 750
Cdd:PRK13524 717 TGDLIAGAGAYT----YNEPGRTYYMSLNTHF 744
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
91-750 2.18e-20

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 96.36  E-value: 2.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  91 PGIN----ASRGDAG----INLRGLSGPRILTIVDGIPIPYlSNSSRQGAFAPANANGGGDTFDFNSLSSLDIVRGADSS 162
Cdd:PRK13528  78 PGVNltgnSASGTRGnnrqIDIRGMGPENTLILIDGVPVTS-RNSVRYSWRGERDTRGDTNWVPPEMVERIEVIRGPAAA 156
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 163 RGGSGMLGGaiVVN--TLEPEDlipvgrDWGAIVkSTYDSEDRSisgsaaaaKKIGNTsilfqggyrkghERDN------ 234
Cdd:PRK13528 157 RYGSGAAGG--VVNiiTKRPTN------DWHGSL-SLYTNQPES--------SKEGAT------------RRANfslsgp 207
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 235 -MGDSDS---YGRY-RTESDPADFDQ-HN------------------LLFKL--RQ--EFEGGhrlgltaerFRRDLQTD 286
Cdd:PRK13528 208 lAGDALTmrlYGNLnKTDADSWDINSsAGtknaagregvrnkdingvLSWKMtpQQilDFEAG---------YSRQGNIY 278
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 287 KRDLQGTGRTYMIDN--YDARELND--RDRVSL----DYDYeATSsdafftsaRAVLYWQ---DLKKESGTNGRTAANVA 355
Cdd:PRK13528 279 AGDTQNSNSSAVTESlaKSGKETNRlyRQNYGLthngIWDW-GQS--------RLGFYYEktnNTRMNEGLAGGGEGRIT 349
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 356 YGR---TNEIENK----------TWGFNGTVTKDFEYSnvrhsvKATLEATTSdwTQYSSALCPTPTTCPSLNNQSevPD 422
Cdd:PRK13528 350 ADQtftTSRLESYrtsgelnvplNWLFEQTLTVGAEWN------RDELNDPSS--TSLTVKDGDIGGISGSAADRS--SK 419
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 423 VESKTIGLSIEDKIEFGDtNFALTPGIRFDWFSydpstsggfasnpalaKFGTlsdrsdqHVSPKVLATYELTPDVQLYT 502
Cdd:PRK13528 420 NKSEISALYVEDNIEPVP-GTNLIPGLRFDYHS----------------EFGS-------NWSPSLNLSQELGDYFKVKA 475
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 503 QLSSAFRAPTVDE------LYSR------FYNAGGNYAQlGNPDLKPETGYGVEMGANFDTGDFNGRLAVFHNRYHNFIE 570
Cdd:PRK13528 476 GIARAFKAPNLYQssegylLYSRgngcpkDITSGGCYLV-GNKNLDPEISVNKEIGLEFTVDDYHASVTYFRNDYQNKIV 554
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 571 TVTSVNATT--GITEFNYTNVSSVTISGIEAS-ADKTFNNGINLHAALAYAY-GRNEETTQRLrSVAPfKAIVGG--GWS 644
Cdd:PRK13528 555 AGDDVIGRTasGAYILQWQNGGKAVVEGLEGNlLVPLMKDRLNWNTNATYMItSEQKDTGNPL-SVIP-KYTINStlDWQ 632
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 645 -NETFGFDLSSTLSAGMLTDHLNTpvTNTADTTFDA----PGYAIVDLTGWWTPDQvpGLRVQAGVYNIFDQEYFnalav 719
Cdd:PRK13528 633 iTQALSANVNWTLYGKQKPRTHAE--SRSEETGGLSgkelGAYSLVGVNVNYDINK--NLRLNVGVSNLFDKQIY----- 703
                        730       740       750
                 ....*....|....*....|....*....|.
gi 516735075 720 RDVNLISTasqprdwYSEPGRTFKVSLTKTF 750
Cdd:PRK13528 704 REGEGANT-------YNEPGRAYYAGVTASF 727
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
54-619 6.37e-20

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 94.69  E-value: 6.37e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  54 RAAPGSVadtpvsTEITDKKLDEKQVTNIEDLGRSVDP-GINASRGDAGINLRGLSGPRILTIVDGipipyLSNSSRQga 132
Cdd:PRK13484  45 RNAPASV------SVITSEQLQKKPVSDLVDAVKDVEGiSITGGNEKPDISIRGLSGDYTLILVDG-----RRQSGRE-- 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 133 fAPANANGG---GDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLepedliPVGRD-W------GAIVKSTYDSED 202
Cdd:PRK13484 112 -SRPNGSGGfeaGFIPPVEAIERIEVIRGPMSSLYGSDAIGGVINIITK------PVNNQtWdgvlglGGIIQEHGKFGN 184
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 203 rSISGSAAAAKKIGNTSILFQ--GG--YRKGherdnmgDSDSYGRYRTesdpadfDQHNLLFKLRQEFEGGHRLGLTAER 278
Cdd:PRK13484 185 -STTNDFYLSGPLIKDKLGLQlyGGmnYRKE-------DSISQGTPAK-------DNKNITATLQFTPTESQKFVFEYGK 249
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 279 --FRRDLQTDKRDLQGTGRTYMIDNYDAREL-NDRDRVSLDYDYEATssdafFTSARAVLYWQDLKKESGTNGRTAAN-- 353
Cdd:PRK13484 250 nnQVHTLTPGESLDAWTMRGNLKQPNSKREThNSRSHWVAAWNAQGE-----ILHPEIAVYQEKVIREVKSGKKDKYNhw 324
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 354 -VAY-GRTNEIENKTwgFNGTVTKdFEYSNVrhsvkatleATTSDWTQYSSalcptpttcpsLNNQSEVPDVESKTIGLS 431
Cdd:PRK13484 325 dLNYeSRKPEITNTI--IDAKVTA-FLPENV---------LTIGGQFQHAE-----------LRDDSATGKKTTETQSVS 381
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 432 IEDKI-----EFGDT-NFALTPGIRFDWFSYdpstsggfasnpalakFGtlsdrsdQHVSPKVLATYELTPDVQLYTQLS 505
Cdd:PRK13484 382 IKQKAvfienEYAATdSLALTGGLRLDNHEI----------------YG-------SYWNPRLYAVYNLTDNLTLKGGIA 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 506 SAFRAPTVDELYSRF--YNAGGNYAQLGNPDLKPETGYGVEMGANFDTGD-FNGRLAVFHNRYHNFIET--VTSVNATTG 580
Cdd:PRK13484 439 KAFRAPSIREVSPGFgtLTQGGASIMYGNRDLKPETSVTEEIGIIYSNDSgFSASATLFNTDFKNKLTSydIGTKDPVTG 518
                        570       580       590
                 ....*....|....*....|....*....|....*....
gi 516735075 581 ITEFNYTNVSSVTISGIEASAdkTFNNGINLHAALAYAY 619
Cdd:PRK13484 519 LNTFIYDNVGEANIRGVELAT--QIPVYDKWHVSANYTF 555
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
48-363 8.49e-18

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 84.15  E-value: 8.49e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  48 IVVKGKRAaPGSVADTPVS-TEITDKKLDEKQVTNIEDLGRSVdPGINASR-----GDAGINLRGLSGPRILTIVDGIPI 121
Cdd:COG4206    1 VVVTATRL-EQSKSDLTGSvTVIDAEELERSGATSLADALRRV-PGVQVSSsggpgSAASISIRGLGSNQTLVLIDGVPL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 122 pylsNSSRQGAFAPANangggdtFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDlipvgrDWGAIVKSTYDSE 201
Cdd:COG4206   79 ----NDPSLGGVDLSL-------IPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKK------GFKGSVSASYGSF 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 202 DRSiSGSAAAAKKIGNTSILFQGGYRKGherDNMGDSDSYGRYRTesdpaDFDQHNLLFKLRQEFEGGHRLGLTAERFRR 281
Cdd:COG4206  142 GTR-RLSASLSGGAGKFSYSLSASYRRS---DGYRYNDPDLRNND-----GYENTSLNARLGYKLGDNGSLSLSGGYSDS 212
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 282 DLQTdkrdlqgtgrtymidnYDARELNDRDRVSLDYDYEATssdAFFTSARAVLYWQDLKKESGTNGRTAANVAYGRTNE 361
Cdd:COG4206  213 ERGY----------------PGAVGSDRNLRLSLSLEYKLS---DGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAG 273

                 ..
gi 516735075 362 IE 363
Cdd:COG4206  274 LS 275
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
41-750 1.82e-16

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 83.40  E-value: 1.82e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  41 DSTVLQKIVVKGKrAAPGSVADTPVSTE-ITDKKLDEKQVTNIEDLGRSVdPGINAS-RGD--AGINLRGLSGPRILTIV 116
Cdd:PRK10064  26 VDDDGETMVVTAS-AVEQNLKDAPASISvITQEDLQRKPVQNLKDVLKEV-PGVQLTnEGDnrKGVSIRGLDSSYTLILI 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 117 DGIPIpylsnSSRQGAFApananggGDTFDFN-----SLSSLDIVRGADSSRGGSGMLGGaiVVNTLEPedliPVGRDWg 191
Cdd:PRK10064 104 DGKRV-----NSRNAVFR-------HNDFDLNwipvdAIERIEVVRGPMSSLYGSDALGG--VVNIITK----KIGQKW- 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 192 aivkstydsedrsiSGSAAAakkigNTSIlfqggyrkgHERDNMGDSDSYGRYrtESDPadfdqhnllfkLRQEFEGGHR 271
Cdd:PRK10064 165 --------------HGTVTV-----DTTI---------QEHRDRGDTYNGQFF--TSGP-----------LIDGVLGMKA 203
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 272 LGLTAERFRRDLQtdKRDLQGTGRTYMIDNYDARELN--------DRDRVSLDYDYEATSSDAfftsaravlywQDLKKE 343
Cdd:PRK10064 204 YGSLAKREKDDPQ--NSTTTDTGETPRIEGFTSRDGNvefawtpnQNHDFTAGYGFDRQDRDS-----------DSLDKN 270
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 344 S--------GTNGR----TAANVAYGrtNEIENKTWGFNGTVTKDfeySNvrhSVKATLEATTSDWTQ---YSSALCPTP 408
Cdd:PRK10064 271 RlerqnyslSHNGRwdygNSELKYYG--EKVENKNPGNSSPITSE---SN---SIDGKYTLPLTAINQfltFGGEWRHDK 342
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 409 TTCPSLNNQSEVPDVESKTIGLSIEDKIEFGDtNFALTPGIRFDwfsyDPSTSGgfasnpalakfgtlsdrsdQHVSPKV 488
Cdd:PRK10064 343 LSDAVNLTGGTSSKTSASQYALFVEDEWRIFE-PLALTTGVRMD----DHETYG-------------------DHWSPRA 398
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 489 LATYELTPDVQLYTQLSSAFRAPTVDELYSRFYNA--GGNYAQLGNPDLKPETGYGVEMGANFDTGD-----FNGRLAVF 561
Cdd:PRK10064 399 YLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNscRGACKIVGSPDLKPETSESWELGLYYMGEEgwlegVESSVTVF 478
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 562 HNR------------------YHNFIETVTSVNAtTGITEFNYTNVSSVTISGIEASADKTFNNGINLHAALAYAYGRNE 623
Cdd:PRK10064 479 RNDvddrisisrtsdvnaapgYQNFVGFETNGRG-RRVPVFRYYNVNKARIQGVETELKIPFNDEWKLSLNYTYNDGRDV 557
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 624 ETTQ-RLRSVAPFKAIVGG-GWSN---ETFGFDLSSTLSAGMLTDhlntpvTNTADTtfdAPGYAIVDLTGWWTPDQvpG 698
Cdd:PRK10064 558 SNGEnKPLSDLPFHTANGTlDWKPlalEDWSFYVSGNYTGQKRAD------SATAKT---PGGYTIWNTGAAWQVTK--D 626
                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|....
gi 516735075 699 LRVQAGVYNIFDqeyfnalavRDVNlistasqpRDWYS--EPGRTFKVSLTKTF 750
Cdd:PRK10064 627 VKLRAGVLNLGD---------KDLS--------RDDYSynEDGRRYFMAVDYRF 663
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
59-172 1.38e-15

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 73.07  E-value: 1.38e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075   59 SVADTPVSTE-ITDKKLDEKQVTNIEDLGRSVdPGINASRGDAG----INLRGLSGPRILTIVDGIPIPYlsnssrqgaf 133
Cdd:pfam07715   1 DLRDTPGSVSvVTAEDIEDQGATNLADALRGV-PGVSVSSGGGGggssISIRGFGSNRVLVLVDGVPLNS---------- 69
                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 516735075  134 aPANANGGGDTFDFNSLSSLDIVRGADSSRGGSGMLGGA 172
Cdd:pfam07715  70 -GGGGSVDLNSIDPEDIERVEVLKGPASALYGSGAIGGV 107
PRK13513 PRK13513
ligand-gated channel protein;
40-711 1.19e-12

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 71.34  E-value: 1.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  40 EDSTVLQKIVVKGKRAAPGSVADTPVS-TEITDKKLDEKQVTNIEDLGRSVdPGINASRG--DAGINLRGLSGPRILTIV 116
Cdd:PRK13513  29 TNTATPTDTMVVTASGFQQRIQDAPASiSVVTREQLENKAYRDVTDALKDV-PGVVVTGGgsTSDISIRGMAAKYTLILV 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 117 DGIPIPylSNSSRqgafaPANANGG---GDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEpedlipVGRDWGAI 193
Cdd:PRK13513 108 DGKRVD--TRSTR-----PNSDGSGieqGWLPPLAAIERIEVVRGPMSSLYGSDAMGGVINIITRK------VQKEWHGS 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 194 VKSTYDSEDRSISG-----SAAAAKKI--GNTSILFQGGYRKgheRDNMGDSDSYGRYRTESDPADF----DQHNLLfkl 262
Cdd:PRK13513 175 LRADATLQEDSKSGdifqtNAYASGPLidGLLGLKVSGLLSH---RSEDKIIDGYNEQRMRNGTATFsltpDDNNEF--- 248
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 263 rqEFEGGhrlgltaerfrRDLQTdkRDlQGTGRTYMIDNYDARELNDRDRVSLDYD--YEATSSDAFFTsaravlywqdl 340
Cdd:PRK13513 249 --DFEIG-----------RYVQD--RN-STPGRTLALNGTNSDTQYDRNNYAITHNgyYDFGNSTSYIQ----------- 301
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 341 KKESGTNGRTAANVaygrTNEIENKTWGFNG----TVTKDFEYSNVR-HSVKATLEATTSDWTQYSSALCptpttcpsln 415
Cdd:PRK13513 302 RDETRNPSRQMKSV----DTIFNTQTSFLLDdhtlSLGGQYRYEELYdKGNQLPSASDLNKLTRWSWALF---------- 367
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 416 nqsevpdvesktiglsIEDKIEFGDtNFALTPGIRFDwfsYDPStsggfasnpalakFGTlsdrsdqHVSPKVLATYELT 495
Cdd:PRK13513 368 ----------------AEDEWQMTN-DFALTGGIRMD---QDQN-------------YGT-------HWTPRLYGVWHLA 407
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 496 PDVQLYTQLSSAFRAPTVDELYSRFYNA--GGNYAQ--LGNPDLKPETGYGVEMGANFDTGD-FNGRLAVFHNRYHNFIE 570
Cdd:PRK13513 408 DQWTLKGGVSTGYRSPDLRQATDNWGQLtgGGGLPAliLGNSDLKPEKSISQEIGILWDNQEnLNASVTLFNTDFKDKIT 487
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 571 TV-----TSVNATTGITEFNY------TNVSSVTISGIEASADKTFNNGINLHAalAYAYGRNEETTQRLRSVAPFKaiV 639
Cdd:PRK13513 488 EVrncdtTNTDGQCVFNGINYdfisdrINVDKANMRGVEATFNWDINQAWSLAT--NYTFTQSEQKSGAFAGQPLNQ--M 563
                        650       660       670       680       690       700       710
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 516735075 640 GGGWSNETFGFDLSSTLSA-------GMLTDHLNTpvTNTADTTfdaPGYAIVDLTGWWTPDQvpGLRVQAGVYNIFDQ 711
Cdd:PRK13513 564 PKHMANATLNWQTTEDFATwirinyrGKTSEYLNR--TSMGSGT---PSYTFVDLGASYQLTK--ELRLMGGVYNLLDK 635
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
445-713 1.80e-10

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 64.24  E-value: 1.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 445 LTPGIRFDWFSYDPSTSGGFASnpALAKFG--TL--SDRSD------QHVSPKVLATYELTPDVQLYTQLSSAFRAPTVD 514
Cdd:PRK10641 342 TTPGTGYVPDGYDQRNTGIYLT--GQQQIGdvTLegAARSDdnsqfgWHGTWQTSAGWEFIDGYRFIASYGTAFKAPNLG 419
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 515 ELYSRFynaggnyaqlGNPDLKPETGYGVEMGANFDTGDFNGRLAVFHNRYHNFIetvtsvnaTTGITEFNYTNVSSVTI 594
Cdd:PRK10641 420 QLYGFY----------GNPNLKPEESKQWEGGFEGLTGPVNWRLSGYRNDIDNLI--------DYDDHTLKYYNVGKATI 481
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 595 SGIEASAdkTFNNGInLHAALAYAY--GRNEETTQRL--RSVAPFKAIVGGGWsnetfgFDLSSTLSAGMLTDHLNTPVT 670
Cdd:PRK10641 482 KGVEWTG--NFDTGP-LTHQVTLDYvdPRNAITDEPLarRAKQQVKYQLDWQL------YDFDWGVTYQYLGTRYDKDYS 552
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 516735075 671 NTADTTFDAPGYAIVDLTGWWtpdqvP---GLRVQAGVYNIFDQEY 713
Cdd:PRK10641 553 TYPYQTVKLGGVSLWDLAVSY-----PvtsHLTVRGKIANLFDKDY 593
PRK13486 PRK13486
TonB-dependent receptor;
69-624 6.64e-09

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 59.27  E-value: 6.64e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  69 ITDKKLDEKQVTNIEDLGRSVDP-GINASRGDAG---INLRGLSGPRILTIVDGIpipylsnssRQGAFAPANANG---- 140
Cdd:PRK13486  49 ISQEELQSSQYHDLAEALRSVEGvDVESGTGKTGgleISIRGMPASYTLILIDGV---------RQGGSSDVTPNGfsam 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 141 -GGDTFDFNSLSSLDIVRGADSSRGGSGMLGGAIVVNTLEPEDlipvgrDWGAIVKSTYDSEDRSISGSAAAAK------ 213
Cdd:PRK13486 120 nTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKNAD------KWLSSVNAGLNLQESNKWGNSSQFNfwssgp 193
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 214 -KIGNTSILFQGG--YRKGHERDNMGD-SDSYGRYRTESDpadfdQHNLLFKLRQEFEGGHRLGLTAERFRRdlQTDKRD 289
Cdd:PRK13486 194 lVDDSVSLQVRGStqQRQGSSVTSLSDtAATRIPYPTESQ-----NYNLGARLDWKASEQDVLWFDMDTTRQ--RYDNRD 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 290 LQGTGRTymiDNYDARELNDRDRVSLDYDYEATssdafFTSARAVLYWQdlkkESGTNGRTAANVAygrtneIENKTWGF 369
Cdd:PRK13486 267 GQLGSLT---GGYDRTLRYERNKISAGYDHTFT-----FGTWKSYLNWN----ETENKGRELVRSV------LKRDKWGL 328
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 370 NGTVTKDFEYSNVRHSVKATLEATTSDWT---QYSSALCPTPTTCPSLNNQsevpdVESKTIGLSIEDKIEFGDTnFALT 446
Cdd:PRK13486 329 AGQPRELKESNLILNSLLLTPLGESHLVTvggEFQSSSMKDGVVLASTGET-----FRQKSWSVFAEDEWHLTDA-LALT 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 447 PGIRFDWFSydpstsggfasnpalaKFGTlsdrsdqHVSPKVLATYELTPDVQLYTQLSSAFRAPTVDELYSRF--YNAG 524
Cdd:PRK13486 403 AGSRYEHHE----------------QFGG-------HFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLHKGIsgVSGQ 459
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 525 GNYAQLGNPDLKPETGYGVEMGANFDTGD-FNGRLAVFHNRYHNFIETVTSVNATTgitefNYTNVSSVTISGIE-ASAD 602
Cdd:PRK13486 460 GKTNLLGNPDLKPEESVSYEAGVYYDNPAgLNANVTGFMTDFSNKIVSYSINDNTN-----SYVNSGKARLHGVEfAGTL 534
                        570       580
                 ....*....|....*....|..
gi 516735075 603 KTFNNGINLhaALAYAYGRNEE 624
Cdd:PRK13486 535 PLWSEDVTL--SLNYTWTRSEQ 554
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
531-747 1.85e-06

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 50.73  E-value: 1.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  531 GNPDLKPETGYGVEMGANFDTgdfNGRLAVFHNRYHNFIETVTSVNATTGITEFNYTNVSSVTISGIEASADKTFNNGIN 610
Cdd:pfam14905 208 GNPNLKPEYTNSFELGYTYKW---KLSLSLSYRYTNDVIQQTFITDDNDNVTYTTYENLGKSNSYGLELSASFNPTKWWS 284
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  611 LHAALAYAYGRNEettqrlrsvapFKAIVGGGWSNETFGFDLSSTLSA-----GMLTDHLNTPVTNtadTTFDAPGYAIV 685
Cdd:pfam14905 285 LNGNLNGYYNKYK-----------IDGSLNSDFSNFGFNWNLNNTFTLpkgwsLQLNGNYRSPRVT---GQGKIKPFYSL 350
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516735075  686 DLtgwwtpdqvpGLR---------VQAGVYNIFDQEYFNALAVRDVNLISTASQPRDWysepgRTFKVSLT 747
Cdd:pfam14905 351 DL----------GLSksflkkkltLSLNVNDIFNTRKFRSTTNYDNGFIQSYNNKWDS-----RSVRLSLS 406
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
439-750 7.77e-06

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 49.64  E-value: 7.77e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  439 GDTNFALTPGIRFDwfsYDPSTSGGFASNPALAKFGTL-----SDRSDQHVSPKVLATYELTPDVQLYTQLSSAFRAPTV 513
Cdd:TIGR01782 518 TGLRLRGNVGVRYE---RTDQTSDGWQSQPAANGTGSVlvpvsADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDF 594
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  514 DELYSRFY-----NAGGNYAQLGNPDLKPETGYGVEMGAN--FDTGDFNGrLAVFHNRYHNFIETVTSVNATTGITEFNY 586
Cdd:TIGR01782 595 GDLAANTSlsddgTGGTVTVSGGNPDLKPYESDNLDLSLEwyFGPGGLLS-AAVFYKDIKNFIVTTTSTETNDGGGGLVV 673
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  587 TNVSSVT---------ISGIEASADKTFN------NGINLHAALAYAYGR-NEETTQRLRSVAPF----KAIVG--GGWS 644
Cdd:TIGR01782 674 AGVLVSRpvnggkagkIRGVELGYQQTFDflpgplSGFGVQANYTYVDSEaDPSVDGVQRRKLPLpglsKNTANatLYYE 753
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075  645 NETFGFDLSSTLSAGMLTDhLNTPVTNTADTTFDAPGYaiVDLT-GWWTPDQvpgLRVQAGVYNIFDQEYFNALAVRdvn 723
Cdd:TIGR01782 754 KGGFSARLSYNYRSDYLLD-VGGSNINRLDRYVDPRGQ--LDLSaSYQVSDH---LSLGLQASNLTNEPSRWYTGGK--- 824
                         330       340
                  ....*....|....*....|....*..
gi 516735075  724 listaSQPRDWYsEPGRTFKVSLTKTF 750
Cdd:TIGR01782 825 -----QRPREYV-ETGRTYMLGLRYKF 845
PRK09840 PRK09840
catecholate siderophore receptor Fiu; Provisional
359-717 2.82e-05

catecholate siderophore receptor Fiu; Provisional


Pssm-ID: 182105 [Multi-domain]  Cd Length: 761  Bit Score: 47.49  E-value: 2.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 359 TNEI-ENKTwgfngTVTKDFEYSNVRHSVKATLEATTSDWTQYSSAlcptPTTCPSLNNQSEVPDV-------------- 423
Cdd:PRK09840 372 SNKIlTNQT-----NLTSTFYTGSIGHDVSTGVEFTRETQTNYGVN----PVTLPAVNLYHPDSSIhpggltrnganang 442
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 424 ESKTIGLSIEDKIEFGDtNFALTPGIRFDWF--SYDPSTSGGFASN-----PALAKFGTLSDR-----SDQHVSPKVLAT 491
Cdd:PRK09840 443 QTDTFAIYAFDTLQLTR-DWELNGGIRLDNYhtEYDSATACGGSGRgaitcPAGVAKGSPVTTvdtakSGNLVNWKAGAL 521
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 492 YELTPDVQLYTQLSSAFRAPTVDElYSRFYNAGGNYAQlgNPDLKPETGYGVEMGANFDTGDfnGRL----AVFHNRYHN 567
Cdd:PRK09840 522 YKLTENGNVYINYAVSQQPPGGSN-FALAQSGSGNSAN--RTDFKPQKANTSEIGTKWQVLD--KRLlltaALFRTDIEN 596
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 568 FIETvtsvNATTGITEFNYTNVSSVTISGI-EASADKTFNNGINL-HAALAYAYGRNEETTQRLrSVAPFKAIVggGWSN 645
Cdd:PRK09840 597 EVEQ----NDDGTYSQYGKKRVEGYELSVAgNITPAWQVIAGYTQqKATVKNGKDVAQDGSSSL-PYTPEHAFT--LWSQ 669
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 516735075 646 ETFGFDLssTLSAGM-LTDHLNTPvtntADTTFDAPGYAivdlTGWWTPDQVPGLRV------QAGVYNIFDQEYFNAL 717
Cdd:PRK09840 670 YQATDDL--SVGGGArYIGSMHRG----SDGAVGTPAFT----EGYWVADAKLGYRVnrnldlQLNVYNLFDTDYVASI 738
PRK14049 PRK14049
ferrioxamine B receptor precursor protein; Provisional
377-617 1.20e-03

ferrioxamine B receptor precursor protein; Provisional


Pssm-ID: 172541 [Multi-domain]  Cd Length: 726  Bit Score: 42.20  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 377 FEYSNVRHSVKATLEATTSDWTQYS--SALCPTPTTCPSLNNQSEVPDVESKTI------GLSIEDKIEFgdTNFALTPG 448
Cdd:PRK14049 373 FDTGAFEHTLLAGVDYTKLRFRALNgrGVSPPLDTKNPTQGRPVAAIDFSTRTVqdqwqlGTYLQDQIRY--DAWTLTAG 450
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 449 IRFDWFSYDpSTSGGFASNPAlakfgTLSDRSDQHVSPKVLATYELTPDVQLYTQLSSAFrAPtvdelysrfyNAGGNYA 528
Cdd:PRK14049 451 GRYDWVSTD-TDTTDLATDSL-----TTVSQKDKEFSGRIGLTYETDFGLAPYISYSTAF-SP----------NAGFNRA 513
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516735075 529 QlGNPdLKPETGYGVEMGANFDTGDFNGRL--AVFH-NRYHNFIETVTSVNATTGITEFNYTNVSSvtiSGIEASADKTF 605
Cdd:PRK14049 514 T-NQP-FKPTESEQQEVGVKYLLPNSNTLItaALFNiDQTNGLYYEVVFLAAGPTNIQVQRGKLRS---RGFELEANTSL 588
                        250
                 ....*....|..
gi 516735075 606 NNGINLHAALAY 617
Cdd:PRK14049 589 DNGLSLIASYTY 600
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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