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Conserved domains on  [gi|516956738|ref|WP_018183661|]
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winged helix-turn-helix domain-containing protein [Kaistia granuli]

Protein Classification

winged helix-turn-helix domain-containing protein( domain architecture ID 10005147)

winged helix-turn-helix domain-containing protein binds DNA and may function as a transcriptional regulator; similar to the N-terminal domain of molybdate-dependent transcriptional regulator ModE

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ModE COG2005
DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];
10-120 1.65e-26

DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];


:

Pssm-ID: 441608 [Multi-domain]  Cd Length: 118  Bit Score: 94.89  E-value: 1.65e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516956738  10 LRFRLVLKPGFALGPGKADLLQAIQESGSLAAAGARLAMSPKRVWGLVREMNTAFRDPLVETEKgGSGGGGSARLTEAGR 89
Cdd:COG2005    7 LKLWLELDGGVFLGPGRIELLEAIDETGSISAAAKAMGMSYKRAWDLIDAMNNLLGEPLVERQT-GGKGGGGARLTPEGR 85

                         90       100       110
                 ....*....|....*....|....*....|.
gi 516956738  90 LVLGRYRAMEAEANAVIAAGVAELRGLMRDD 120
Cdd:COG2005   86 RLLALYRRLEAEAQRALAALFEELFALLRSK 116
 
Name Accession Description Interval E-value
ModE COG2005
DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];
10-120 1.65e-26

DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];


Pssm-ID: 441608 [Multi-domain]  Cd Length: 118  Bit Score: 94.89  E-value: 1.65e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516956738  10 LRFRLVLKPGFALGPGKADLLQAIQESGSLAAAGARLAMSPKRVWGLVREMNTAFRDPLVETEKgGSGGGGSARLTEAGR 89
Cdd:COG2005    7 LKLWLELDGGVFLGPGRIELLEAIDETGSISAAAKAMGMSYKRAWDLIDAMNNLLGEPLVERQT-GGKGGGGARLTPEGR 85

                         90       100       110
                 ....*....|....*....|....*....|.
gi 516956738  90 LVLGRYRAMEAEANAVIAAGVAELRGLMRDD 120
Cdd:COG2005   86 RLLALYRRLEAEAQRALAALFEELFALLRSK 116
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
29-89 3.18e-04

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 36.21  E-value: 3.18e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516956738   29 LLQAIQESGSLAAAGARLAMSPKRVWGLVREMNTAFRDPLVETekggsgGGGSARLTEAGR 89
Cdd:pfam00126   6 LFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFER------TTRGVRLTEAGE 60
 
Name Accession Description Interval E-value
ModE COG2005
DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];
10-120 1.65e-26

DNA-binding transcriptional regulator ModE (molybdenum-dependent) [Transcription];


Pssm-ID: 441608 [Multi-domain]  Cd Length: 118  Bit Score: 94.89  E-value: 1.65e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516956738  10 LRFRLVLKPGFALGPGKADLLQAIQESGSLAAAGARLAMSPKRVWGLVREMNTAFRDPLVETEKgGSGGGGSARLTEAGR 89
Cdd:COG2005    7 LKLWLELDGGVFLGPGRIELLEAIDETGSISAAAKAMGMSYKRAWDLIDAMNNLLGEPLVERQT-GGKGGGGARLTPEGR 85

                         90       100       110
                 ....*....|....*....|....*....|.
gi 516956738  90 LVLGRYRAMEAEANAVIAAGVAELRGLMRDD 120
Cdd:COG2005   86 RLLALYRRLEAEAQRALAALFEELFALLRSK 116
HTH_1 pfam00126
Bacterial regulatory helix-turn-helix protein, lysR family;
29-89 3.18e-04

Bacterial regulatory helix-turn-helix protein, lysR family;


Pssm-ID: 459683 [Multi-domain]  Cd Length: 60  Bit Score: 36.21  E-value: 3.18e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516956738   29 LLQAIQESGSLAAAGARLAMSPKRVWGLVREMNTAFRDPLVETekggsgGGGSARLTEAGR 89
Cdd:pfam00126   6 LFVAVAETGSFTAAAERLGLSQPAVSRQIKRLEEELGVPLFER------TTRGVRLTEAGE 60
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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