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Conserved domains on  [gi|516958783|ref|WP_018184640|]
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carbohydrate ABC transporter permease [Kaistia granuli]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 11417684)

carbohydrate ABC transporter permease, part of a periplasmic binding protein (PBP)-dependent ABC transporter may be involved in transport of one or more of a variety of mono-, di-, or polysaccharides, such as trehalose/maltose (MalG) and alginate (AlgM); responsible for translocation of the substrate across the membrane

Gene Ontology:  GO:0055085|GO:0008643
PubMed:  19234479|27273632
TCDB:  3.A.1.1.

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 1-284 1.94e-85

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 256.95  E-value: 1.94e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783   1 MSAPARTRFRlpSLEDALRGAAIVIVSAIIFFPVYWMIVSSIRPSAESLSFPPPLWPGSIDVQSYFQLFVEKPIARWLLL 80
Cdd:COG0395    1 MSATARRRRR--RLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  81 STLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPL 160
Cdd:COG0395   79 SLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPF 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 161 CAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLYTASLGLATL 240
Cdd:COG0395  159 GIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASF 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 516958783 241 MTQLDTPLFVLMAAGVTFSILPVFFYMAIQRHLLRGLTAGAVKG 284
Cdd:COG0395  239 QGQYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 1-284 1.94e-85

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 256.95  E-value: 1.94e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783   1 MSAPARTRFRlpSLEDALRGAAIVIVSAIIFFPVYWMIVSSIRPSAESLSFPPPLWPGSIDVQSYFQLFVEKPIARWLLL 80
Cdd:COG0395    1 MSATARRRRR--RLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  81 STLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPL 160
Cdd:COG0395   79 SLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPF 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 161 CAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLYTASLGLATL 240
Cdd:COG0395  159 GIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASF 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 516958783 241 MTQLDTPLFVLMAAGVTFSILPVFFYMAIQRHLLRGLTAGAVKG 284
Cdd:COG0395  239 QGQYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
malG PRK10998
maltose ABC transporter permease MalG;
28-284 6.31e-21

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 90.15  E-value: 6.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  28 AIIFFPVYWMIVSSIRPSaeslSFPP-PLWPGSIDVQSY-FQLFV------------EKPIARWLLLSTLVASLTVIGTL 93
Cdd:PRK10998  25 ALIMFPLLMVIAISLREG----NFATgSLIPEQISWEHWkLALGFsvehadgrvtppPFPVLLWLWNSVKVAGITAIGIV 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  94 ILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGwtDNLWALAL-LHTAFV------VPLCAWVLK 166
Cdd:PRK10998 101 ALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLG--QYIPFIGLnTHGGVIfaylggIALHVWTIK 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 167 ASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLYTASLGlatlMTQLDT 246
Cdd:PRK10998 179 GYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVG----MQQYLN 254

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 516958783 247 P---LFVLMAAGVTFSILPV-FFYMAIQRHLLRGLTAGAVKG 284
Cdd:PRK10998 255 PqnyLWGDFAAAAVLSAIPItVVFLLAQRWLVGGLTAGGVKG 296
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 78-264 1.96e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.30  E-value: 1.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  78 LLLSTLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNL----WALALLH 153
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILpglgLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 154 TAFVVPLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFAStLITKNDLYTA 233
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVS-FLGGGEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|.
gi 516958783 234 SLGLATLMTQLDTPLFVLMAAGVTFSILPVF 264
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-277 8.84e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.92  E-value: 8.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  108 WPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPLCAWVLKASFDAVPKEIVEAALIDGCDR 187
Cdd:pfam00528  14 RRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  188 WKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLytASLGLATLMTQLDTPLFVLMAAGVTFSILPVFFYM 267
Cdd:pfam00528  94 WQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL--GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVD 171

                         170
                  ....*....|
gi 516958783  268 AIQRHLLRGL 277
Cdd:pfam00528 172 ILQRLLDPRV 181
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 157-211 4.03e-03

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 38.02  E-value: 4.03e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 516958783  157 VVPLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAF 211
Cdd:TIGR02138 162 ILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVLGL 216
 
Name Accession Description Interval E-value
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 1-284 1.94e-85

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 256.95  E-value: 1.94e-85
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783   1 MSAPARTRFRlpSLEDALRGAAIVIVSAIIFFPVYWMIVSSIRPSAESLSFPPPLWPGSIDVQSYFQLFVEKPIARWLLL 80
Cdd:COG0395    1 MSATARRRRR--RLGRILLYLLLILLALLFLFPLYWMVVTSFKPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFGRYLLN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  81 STLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPL 160
Cdd:COG0395   79 SLIVAVVSTVLSLLLSSLAAYALARFRFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQLGLLNTYWGLILPYLAFGLPF 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 161 CAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLYTASLGLATL 240
Cdd:COG0395  159 GIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAWNDFLWPLILLTSPDLRTLPVGLASF 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 516958783 241 MTQLDTPLFVLMAAGVTFSILPVFFYMAIQRHLLRGLTAGAVKG 284
Cdd:COG0395  239 QGQYGTDWGLLMAAAVIATLPVLILFLFLQRYFVRGLTAGAVKG 282
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 3-284 3.19e-69

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 215.79  E-value: 3.19e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783   3 APARTRFRLPSLEDALRGAAIVIVSAIIFFPVYWMIVSSIRPSaeSLSFPPPLWPGSIDVQSYFQLFVEKPIARWLLLST 82
Cdd:COG3833    2 SRRKSRKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPG--GSLYSSSLIPENFTLENYKKLFTETPFLRWFLNSL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  83 LVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPLCA 162
Cdd:COG3833   80 IVAVVTAIISVFLAALAAYAFSRFRFKGRKAGLLALLLLQMFPAFLALVALYLLLSALGLLNTLLGLILVYLGGAIPFNT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 163 WVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLYTASLGLATLMT 242
Cdd:COG3833  160 WLMKGYFDTIPKELDEAAKIDGASHFQIFFRIILPLAKPILAVVALLSFIGPWNDFILASVLLRSPENYTLAVGLYSFVS 239

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 516958783 243 QLDTPLFVLMAAG-VTFSILPVFFYMAIQRHLLRGLTAGAVKG 284
Cdd:COG3833  240 DQRNTNWGVFAAGaVLVAIPIVILFLFLQRYLVSGLTAGGVKG 282
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 17-276 8.36e-29

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 110.59  E-value: 8.36e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  17 ALRGAAIVIVSAIIFFPVYWMIVSSIRPSaESLSFPPPLWpgsiDVQSYFQLFVEKPIARWLLLSTLVASLTVIGTLILV 96
Cdd:COG1177    7 LLLRLFLALVLLFLYLPILVLVLYSFNDS-WFLTFPPEGF----TLRWYAELFSDPRLLDALLNSLLIALLSTLLATVLG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  97 IPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPLCAWVLKASFDAVPKEI 176
Cdd:COG1177   82 TPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILAHVVFTLPFVVLVVLARLQGFDPSL 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 177 VEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFAStLITKNDLYTASLGLATLMTQLDTPlfVLMAAGV 256
Cdd:COG1177  162 EEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITL-FLAGPGVTTLPVYIYSMIRRGISP--EINALST 238

                        250       260
                 ....*....|....*....|
gi 516958783 257 TFSILPVFFYMAIQRHLLRG 276
Cdd:COG1177  239 LLILLSLLLLLLAERLRRRG 258
malG PRK10998
maltose ABC transporter permease MalG;
28-284 6.31e-21

maltose ABC transporter permease MalG;


Pssm-ID: 182891  Cd Length: 296  Bit Score: 90.15  E-value: 6.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  28 AIIFFPVYWMIVSSIRPSaeslSFPP-PLWPGSIDVQSY-FQLFV------------EKPIARWLLLSTLVASLTVIGTL 93
Cdd:PRK10998  25 ALIMFPLLMVIAISLREG----NFATgSLIPEQISWEHWkLALGFsvehadgrvtppPFPVLLWLWNSVKVAGITAIGIV 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  94 ILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGwtDNLWALAL-LHTAFV------VPLCAWVLK 166
Cdd:PRK10998 101 ALSTTCAYAFARMRFKGKATLLKGMLIFQMFPAVLSLVALYALFDRLG--QYIPFIGLnTHGGVIfaylggIALHVWTIK 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 167 ASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLYTASLGlatlMTQLDT 246
Cdd:PRK10998 179 GYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVG----MQQYLN 254

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 516958783 247 P---LFVLMAAGVTFSILPV-FFYMAIQRHLLRGLTAGAVKG 284
Cdd:PRK10998 255 PqnyLWGDFAAAAVLSAIPItVVFLLAQRWLVGGLTAGGVKG 296
PRK10973 PRK10973
sn-glycerol-3-phosphate ABC transporter permease UgpE;
21-277 1.93e-20

sn-glycerol-3-phosphate ABC transporter permease UgpE;


Pssm-ID: 182875 [Multi-domain]  Cd Length: 281  Bit Score: 88.25  E-value: 1.93e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  21 AAIVIVSAIIFFPVYWMIVSSIRPSAESLSFPPPLWPGSIDVQSYFQLFVE------KPIARWLLLSTLVASLTVIGTLI 94
Cdd:PRK10973  14 TMLILGIAVILFPLYVAFVAATLDKQAVFAVPMTLIPGTHLLENIANIWVNgvgnnsAPFGRMLLNSFVMAFSITVGKIT 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  95 LVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALlhtafvvPLCA-----WVLKASF 169
Cdd:PRK10973  94 VSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTL-------PLMAsatatFLFRQFF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 170 DAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLYTASLGLATLMTQLD--TP 247
Cdd:PRK10973 167 MTLPDELVEAARIDGASPMRFFWDIVLPLSKTNLAALFVITFIYGWNQYLWPLLIITDVSLGTAVAGIKGMIATGEgtTE 246

                        250       260       270
                 ....*....|....*....|....*....|
gi 516958783 248 LFVLMAAGVTFSILPVFFYMAIQRHLLRGL 277
Cdd:PRK10973 247 WNQVMAAMLLTLIPPVVIVLAMQRAFVRGL 276
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
17-211 4.35e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 71.73  E-value: 4.35e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  17 ALRGAAIVIVSAIIFFPVYWMIVSSIRPsaeslsfppplwpgsiDVQSYFQLFVEKPIARWLLLSTLVASLTVIGTLILV 96
Cdd:COG1178   11 LLLLLLALLLALLVLLPLLALLLRAFTD----------------GLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLG 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  97 IPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALY-----------RGLGWTD----NLWALALLHTAFVVPLC 161
Cdd:COG1178   75 VPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFgpngllntllrALFGLEPpdiyGLGGIILVLVLFNYPYV 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 516958783 162 AWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAF 211
Cdd:COG1178  155 YLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVF 204
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
2-218 6.73e-14

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 71.35  E-value: 6.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783   2 SAPARTRFRLPSLEDALRGAAIVIVSAIIFFPVYWMIVSSIRPsaeslsfpppLWPGSIDVQSYFQLFVEKPIARWLLLS 81
Cdd:COG1178  274 RARRPRRVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSLTK----------ALDDNLTLDNYRFVLLDPSLLRALLNS 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  82 TLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYR---GLGWTDNLWALALLHTAFVV 158
Cdd:COG1178  344 LLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNrplPLLLYGTLAILVLAYVVRFL 423

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 159 PLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEY 218
Cdd:COG1178  424 PFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKEL 483
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 78-264 1.96e-13

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 67.30  E-value: 1.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  78 LLLSTLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNL----WALALLH 153
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILpglgLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 154 TAFVVPLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFAStLITKNDLYTA 233
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVS-FLGGGEAPGP 159

                        170       180       190
                 ....*....|....*....|....*....|.
gi 516958783 234 SLGLATLMTQLDTPLFVLMAAGVTFSILPVF 264
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 108-277 8.84e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 56.92  E-value: 8.84e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  108 WPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPLCAWVLKASFDAVPKEIVEAALIDGCDR 187
Cdd:pfam00528  14 RRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  188 WKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFASTLITKNDLytASLGLATLMTQLDTPLFVLMAAGVTFSILPVFFYM 267
Cdd:pfam00528  94 WQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL--GLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVD 171

                         170
                  ....*....|
gi 516958783  268 AIQRHLLRGL 277
Cdd:pfam00528 172 ILQRLLDPRV 181
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 1-211 2.94e-09

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 56.69  E-value: 2.94e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783   1 MSAPARTRFRLPsledALRGAAIVIVSAIIFFPVYWMIVSSIRPSAESLSFPPPLwpgsiDVQSYFQLFVEKPIARWLLL 80
Cdd:COG1176    1 MSAALRRRLRPL----LLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGF-----TLENYARLFTDPLYLKVLLR 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  81 STLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVV----------APILALYRGLGWTDNlwALA 150
Cdd:COG1176   72 TLWIALLTTLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTyawivllgrnGLLNSLLLALGLIDE--PLR 149

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 151 LLHTAFVV---------PLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAF 211
Cdd:COG1176  150 LLYTEFAVviglvyvylPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVF 219
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 78-218 4.22e-09

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 55.91  E-value: 4.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  78 LLLSTLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAF- 156
Cdd:COG0555   56 LKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGIKVAFt 135

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 516958783 157 ---VV--------PLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEY 218
Cdd:COG0555  136 plgIVlaqtfvslPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEF 208
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 18-211 8.47e-09

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 54.99  E-value: 8.47e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  18 LRGAAIVIVSAIIFFPVYWMIVSSIRPSAESLSfppplWPGsIDVQSYFQLFVEKPIARWLLLSTLVASL-----TVIGT 92
Cdd:PRK09500   5 LRGGFMTLVYAYLYIPIIILIVNSFNSSRFGIN-----WKG-FTTKWYELLFNNDSLLQAAQHSLTMAVFsatfaTLIGS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  93 LilvipAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALALLHTAFVVPLCAWVLKASFDAV 172
Cdd:PRK09500  79 L-----TAVALYRYRFRGKKFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFAHITFCLPFVVVTVYSRLKGF 153

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 516958783 173 PKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAF 211
Cdd:PRK09500 154 DVRMLEAAKDLGASEFTILRKIILPLALPAVAAGWLLSF 192
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
1-216 2.30e-08

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 53.99  E-value: 2.30e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783   1 MSAPARTRFRLPSLEDALRGA-----AIVIVSAIIFFPVYWMIVSSIRPSaeSLSFPPPLWPGsidVQSYFQLFVEKPIA 75
Cdd:COG1175    1 MTTTTSAAARRRRRRRRLAAYlfllpALLLLLVFVLYPLLYTLYLSFTDW--NLLGPPPEFVG---LDNYARLFTDPRFW 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  76 RWLLLSTLVASLTVIGTLILVIPAAYALSRLYWpGRSAFGLLLLFTQMMPAAVVVA-----------PILALYRGLGWTD 144
Cdd:COG1175   76 NALGNTLLFTVVSVPLQLVLGLLLALLLNRKLR-GRGFFRTLFFLPWVISPVVVALiwkwlfnpdygLLNALLGALGLEP 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 145 ---------NLWALALLHTAFVVPLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASW 215
Cdd:COG1175  155 inwlgdpslALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGAL 234


                 .
gi 516958783 216 N 216
Cdd:COG1175  235 Q 235
modB PRK09421
molybdate ABC transporter permease subunit;
78-218 4.57e-06

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 46.45  E-value: 4.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  78 LLLSTLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALY--RGL--GWTDNL------- 146
Cdd:PRK09421  11 VLLSLKVSSVAVLFSLPFGILVAWLLARCRFPGKSLLDSLLHLPLVLPPVVTGYLLLISMgrRGFigQWLYEWfgisfaf 90

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 516958783 147 -WALALLHTAFV-VPLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEY 218
Cdd:PRK09421  91 sWRGAALAAAVMaFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGEF 164
YnjC COG4135
ABC-type uncharacterized transport system YnjBCD, permease component [General function ...
 15-219 7.99e-04

ABC-type uncharacterized transport system YnjBCD, permease component [General function prediction only];


Pssm-ID: 443310 [Multi-domain]  Cd Length: 564  Bit Score: 40.62  E-value: 7.99e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  15 EDALRGAAIVIVSAIIFFPVYWMIVSSIRPSAESLSFPPpLWPGSIDVQSYFQLFVEkpIARWLLLSTLVASLTVIGTLI 94
Cdd:COG4135  298 DPALRRLGLALMLLIALLSLLGLALLLLWSFAGRWRFPD-ALPSSWTLRFWQRAAPG--LLEPLGNTLLLALASALIALV 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  95 LVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVA--PILALYRGLGWTdnLWALALLHTAFVVPLCAWVLKASFDAV 172
Cdd:COG4135  375 LVLACLEAEARRGRRPGRRALWLLYLPLLVPQIAFLFglQVLLLRLGLDGT--WLAVIWAHLVFVLPYVFLSLAGPWRAL 452

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 516958783 173 PKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYL 219
Cdd:COG4135  453 DPRYAQVAASLGASPWRVFWRVKLPLLLRPILTAAAVGFAVSVAQYL 499
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 168-211 1.36e-03

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 39.69  E-value: 1.36e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 516958783 168 SFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAF 211
Cdd:COG0573  178 ALRAVPRSLREAALALGATRWETIRKVVLPAARSGIIAAVILGL 221
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 157-211 4.03e-03

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 38.02  E-value: 4.03e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 516958783  157 VVPLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAF 211
Cdd:TIGR02138 162 ILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVLGL 216
thiP PRK09433
thiamine transporter membrane protein; Reviewed
 81-200 4.45e-03

thiamine transporter membrane protein; Reviewed


Pssm-ID: 181853 [Multi-domain]  Cd Length: 525  Bit Score: 38.28  E-value: 4.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  81 STLVASLTVIGTLILVIPAAYALSRLYWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGLGWTDNLWALA---------- 150
Cdd:PRK09433  49 SFWQAFLSALLSVLPAIPLARALYRRRFPGRGLLLRLCAMTLVLPVLVAVFGLLSVYGRSGWLAQLLQALglewpfsiyg 128

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 516958783 151 -----LLHTAFVVPLCAWVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTR 200
Cdd:PRK09433 129 lqgilLAHVFFNLPLATRLLLQALESIPAEQRQLAAQLGMRGWQFFRLVEWPYLR 183
PRK10592 PRK10592
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 10-222 6.31e-03

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182574  Cd Length: 281  Bit Score: 37.52  E-value: 6.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  10 RLPSLEDALRGAAIVIVSAIIFFPVYWMIVSSIRPSAESlsfppPLWPGsIDVQSYFQLFVEKPIARWLLLSTLVASLTV 89
Cdd:PRK10592   3 NLPVVRSPWRIVILVLGFTFLYAPMLMLVIYSFNSSKLV-----TVWAG-WSTRWYGELFRDDAMMSAVGLSLTIAACAA 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783  90 IGTLILVIPAAYALSRL-YWPGRSAFGLLLLFTQMMPAAVVVAPILALYRGL----GWTDN--LWALALLHTAFVVPLCA 162
Cdd:PRK10592  77 TAAAILGTIAAVVMVRFgRFRGSNGFAFMITAPLVMPDVITGLSLLLLFVALahaiGWPADrgMLTIWLAHVTFCTAYVA 156

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 516958783 163 WVLKASFDAVPKEIVEAALIDGCDRWKVLWLVVLPLTRPGLVAVSVIAFFASWNEYLFAS 222
Cdd:PRK10592 157 VVISSRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIAS 216
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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