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Conserved domains on  [gi|516959219|ref|WP_018184868|]
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enoyl-CoA hydratase/isomerase family protein [Kaistia granuli]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 10787157)

enoyl-CoA hydratase/isomerase family protein similar to human ethylmalonyl-CoA decarboxylase that decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA

CATH:  3.90.226.10
Gene Ontology:  GO:0016829
PubMed:  12467702|22016388

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-254 2.34e-69

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


:

Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 213.88  E-value: 2.34e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   7 LRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNR-RAEFIAYQL 85
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAAdPEEARAFAR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  86 ESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLA 165
Cdd:COG1024   80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 166 ARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQE 245
Cdd:COG1024  160 GRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDARE 239

                 ....*....
gi 516959219 246 GIDAFLDKR 254
Cdd:COG1024  240 GIAAFLEKR 248
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-254 2.34e-69

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 213.88  E-value: 2.34e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   7 LRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNR-RAEFIAYQL 85
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAAdPEEARAFAR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  86 ESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLA 165
Cdd:COG1024   80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 166 ARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQE 245
Cdd:COG1024  160 GRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDARE 239

                 ....*....
gi 516959219 246 GIDAFLDKR 254
Cdd:COG1024  240 GIAAFLEKR 248
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
1-260 1.00e-56

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 182.17  E-value: 1.00e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGaGEKAFVAGADIAEYRGNRRAEF 80
Cdd:PRK08138   4 TATDVVLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATAGAIEM 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 iaYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVAS 160
Cdd:PRK08138  83 --YLRHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 161 DMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGT 240
Cdd:PRK08138 161 RMALTGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDS 240
                        250       260
                 ....*....|....*....|
gi 516959219 241 ADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK08138 241 EDQKEGMDAFLEKRKPAYKG 260
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
10-200 6.53e-53

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 170.05  E-value: 6.53e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  10 DLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEFIAYQL--ES 87
Cdd:cd06558    4 ERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEARAFirEL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  88 RRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAAR 167
Cdd:cd06558   83 QELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGR 162
                        170       180       190
                 ....*....|....*....|....*....|...
gi 516959219 168 RITGERAHQLGLAVECVADDALMEMAESRARAM 200
Cdd:cd06558  163 RISAEEALELGLVDEVVPDEELLAAALELARRL 195
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-260 2.30e-48

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 160.22  E-value: 2.30e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGaGEKAFVAGADIAEYRGNRRAEFIAYQLESRRVFDK 93
Cdd:pfam00378   5 GVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   94 LEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGER 173
Cdd:pfam00378  84 LYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQE 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  174 AHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQEGIDAFLDK 253
Cdd:pfam00378 164 ALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEK 243

                  ....*..
gi 516959219  254 RDPVFKG 260
Cdd:pfam00378 244 RKPPWED 250
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
10-179 2.64e-21

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 92.98  E-value: 2.64e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   10 DLEPGIVRLTFNRPD-KLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAEfIAYQL--E 86
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQ-EVTQLsqE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   87 SRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVcATSARLGLPEGLLGLSPG---GGGTQRLTRAVGRIVASDMM 163
Cdd:TIGR02441  97 GQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRI-ATKDRKTLLGLPEVMLGLlpgAGGTQRLPKLTGVPAALDMM 175
                         170
                  ....*....|....*.
gi 516959219  164 LAARRITGERAHQLGL 179
Cdd:TIGR02441 176 LTGKKIRADRAKKMGI 191
 
Name Accession Description Interval E-value
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
7-254 2.34e-69

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 213.88  E-value: 2.34e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   7 LRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNR-RAEFIAYQL 85
Cdd:COG1024    1 VLVEREGGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAAAAdPEEARAFAR 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  86 ESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLA 165
Cdd:COG1024   80 GLQRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLT 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 166 ARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQE 245
Cdd:COG1024  160 GRRIDAEEALELGLVNRVVPDDELLAAALALAARLAAGPPLALAATKRALNAALEAPLDEALELEAEAFAELFASEDARE 239

                 ....*....
gi 516959219 246 GIDAFLDKR 254
Cdd:COG1024  240 GIAAFLEKR 248
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
1-260 1.00e-56

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 182.17  E-value: 1.00e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGaGEKAFVAGADIAEYRGNRRAEF 80
Cdd:PRK08138   4 TATDVVLLERPADGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTG-GEKVFAAGADIKEFATAGAIEM 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 iaYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVAS 160
Cdd:PRK08138  83 --YLRHTERYWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 161 DMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGT 240
Cdd:PRK08138 161 RMALTGCMVPAPEALAIGLVSEVVEDEQTLPRALELAREIARMPPLALAQIKEVVLAGADAPLDAALALERKAFQLLFDS 240
                        250       260
                 ....*....|....*....|
gi 516959219 241 ADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK08138 241 EDQKEGMDAFLEKRKPAYKG 260
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
3-261 6.31e-55

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 177.62  E-value: 6.31e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   3 EPLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAEFIA 82
Cdd:PRK07657   2 LQNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRH 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  83 YQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDM 162
Cdd:PRK07657  82 AVSLIRTTMEMVEQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 163 MLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTAD 242
Cdd:PRK07657 162 IYTGRRISAQEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRQAKEAISNGIQVDLHTGLQIEKQAYEGTIPTKD 241
                        250
                 ....*....|....*....
gi 516959219 243 GQEGIDAFLDKRDPVFKGI 261
Cdd:PRK07657 242 RLEGLQAFKEKRKPMYKGE 260
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
14-260 3.77e-54

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 175.57  E-value: 3.77e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAE-FIAYQLESRRVFD 92
Cdd:PRK06144  17 GIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEdAVAYERRIDRVLG 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  93 KLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGT-QRLTRAVGRIVASDMMLAARRITG 171
Cdd:PRK06144  97 ALEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFPIARTLGNCLSMSNlARLVALLGAARVKDMLFTARLLEA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 172 ERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAqgfeQEVLFRLYGTADGQEGIDAFL 251
Cdd:PRK06144 177 EEALAAGLVNEVVEDAALDARADALAELLAAHAPLTLRATKEALRRLRREGLPDG----DDLIRMCYMSEDFREGVEAFL 252

                 ....*....
gi 516959219 252 DKRDPVFKG 260
Cdd:PRK06144 253 EKRPPKWKG 261
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
12-260 1.94e-53

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 173.78  E-value: 1.94e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  12 EPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAEFIAYQLESRRVF 91
Cdd:PRK05809  11 EGHIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  92 DKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITG 171
Cdd:PRK05809  91 RKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 172 ERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQEGIDAFL 251
Cdd:PRK05809 171 EEALRIGLVNKVVEPEKLMEEAKALANKIAANAPIAVKLCKDAINRGMQVDIDTAVAIEAEDFGECFSTEDQTEGMTAFV 250

                 ....*....
gi 516959219 252 DKRDPVFKG 260
Cdd:PRK05809 251 EKREKNFKN 259
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
10-200 6.53e-53

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 170.05  E-value: 6.53e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  10 DLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEFIAYQL--ES 87
Cdd:cd06558    4 ERDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGAG-KAFCAGADLKELAALSDAGEEARAFirEL 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  88 RRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAAR 167
Cdd:cd06558   83 QELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGR 162
                        170       180       190
                 ....*....|....*....|....*....|...
gi 516959219 168 RITGERAHQLGLAVECVADDALMEMAESRARAM 200
Cdd:cd06558  163 RISAEEALELGLVDEVVPDEELLAAALELARRL 195
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
1-260 1.09e-52

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 171.59  E-value: 1.09e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYrGNRRAEF 80
Cdd:PRK06688   1 MTMVTDLLVELEDGVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAG-RAFSAGGDIKDF-PKAPPKP 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVAS 160
Cdd:PRK06688  79 PDELAPVNRFLRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAA 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 161 DMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGT 240
Cdd:PRK06688 159 EMLLLGEPLSAEEALRIGLVNRVVPAAELDAEADAQAAKLAAGPASALRYTKRAINAATLTELEEALAREAAGFGRLLRT 238
                        250       260
                 ....*....|....*....|
gi 516959219 241 ADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK06688 239 PDFREGATAFIEKRKPDFTG 258
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
12-260 1.11e-52

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 171.49  E-value: 1.11e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  12 EPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAgEKAFVAGADIAEYRgnrrAEFIAYQLESRRV- 90
Cdd:PRK09674   9 QQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGN-ARFFAAGADLNEMA----EKDLAATLNDPRPq 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  91 -FDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRI 169
Cdd:PRK09674  84 lWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESI 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 170 TGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQEGIDA 249
Cdd:PRK09674 164 TAQQAQQAGLVSEVFPPELTLERALQLASKIARHSPLALRAAKQALRQSQEVDLQAGLAQERQLFTLLAATEDRHEGISA 243
                        250
                 ....*....|.
gi 516959219 250 FLDKRDPVFKG 260
Cdd:PRK09674 244 FLEKRTPDFKG 254
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
14-260 2.30e-48

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 160.22  E-value: 2.30e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGaGEKAFVAGADIAEYRGNRRAEFIAYQLESRRVFDK 93
Cdd:pfam00378   5 GVAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTL 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   94 LEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGER 173
Cdd:pfam00378  84 LYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQE 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  174 AHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQEGIDAFLDK 253
Cdd:pfam00378 164 ALKWGLVDKVVPEDQLLDEARELAEKLAEKSPAALAQLKKALNAKLEDALPTQLEAEARLFYSTFSKDDIIEGLQAFLEK 243

                  ....*..
gi 516959219  254 RDPVFKG 260
Cdd:pfam00378 244 RKPPWED 250
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
11-260 1.93e-47

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 158.26  E-value: 1.93e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  11 LEPGIVRLTFNRPDKlNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRG-NRRAEFIAYQLESRR 89
Cdd:PRK07658   8 VEDHVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFTSvTEAEQATELAQLGQV 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  90 VFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRI 169
Cdd:PRK07658  86 TFERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPI 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 170 TGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALpvAQGFEQEV-LF-RLYGTADGQEGI 247
Cdd:PRK07658 166 TGAEALKWGLVNGVFPEETLLDDAKKLAKKIAGKSPATTRAVLELLQTTKSSSY--YEGVKREAkIFgEVFTSEDAKEGV 243
                        250
                 ....*....|...
gi 516959219 248 DAFLDKRDPVFKG 260
Cdd:PRK07658 244 QAFLEKRKPSFSG 256
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
14-260 1.62e-46

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 156.02  E-value: 1.62e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNR--RAEFIAYQLESRRVF 91
Cdd:PRK06127  20 GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRsdAEAVAAYEQAVEAAQ 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  92 DKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITG 171
Cdd:PRK06127 100 AALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDA 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 172 ERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQ-GPDAALPVAQGFEQEVLfRLYGTADGQEGIDAF 250
Cdd:PRK06127 180 AEALRIGLVHRVTAADDLETALADYAATIAGNAPLTLRAAKRAIAElLKDEPERDMAACQALVA-ACFDSEDYREGRAAF 258
                        250
                 ....*....|
gi 516959219 251 LDKRDPVFKG 260
Cdd:PRK06127 259 MEKRKPVFKG 268
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
1-260 1.80e-46

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 155.58  E-value: 1.80e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDLEPgIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEY-RGNRRA- 78
Cdd:PRK06494   1 MALPFSTVERKGH-VTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQaAGGKRGw 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  79 -EFIAYQLESRrvFDkleaLAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRI 157
Cdd:PRK06494  80 pESGFGGLTSR--FD----LDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLK 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 158 VASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGpdAALPVAQGFEQEVLF-- 235
Cdd:PRK06494 154 RAMGMILTGRRVTAREGLELGFVNEVVPAGELLAAAERWADDILACSPLSIRASKQAVYRG--LEVSLEEAITAQRDYpa 231
                        250       260
                 ....*....|....*....|....*..
gi 516959219 236 --RLYGTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK06494 232 veARRASQDYIEGPKAFAEKRPPRWKG 258
PLN02600 PLN02600
enoyl-CoA hydratase
14-260 7.21e-43

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 146.10  E-value: 7.21e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAEFIAYQLESRRVFDK 93
Cdd:PLN02600   4 GIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSS 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  94 LEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGER 173
Cdd:PLN02600  84 LEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGARE 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 174 AHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQEGIDAFLDK 253
Cdd:PLN02600 164 AASMGLVNYCVPAGEAYEKALELAQEINQKGPLAIKMAKKAINEGSEVDMASGLEIEEECYEQVLKTKDRLEGLAAFAEK 243

                 ....*..
gi 516959219 254 RDPVFKG 260
Cdd:PLN02600 244 RKPVYTG 250
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
1-258 1.32e-41

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 143.36  E-value: 1.32e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLrdDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRA-- 78
Cdd:PRK05980   1 MTDTVLI--EIRDGIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAga 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  79 -----EFIAyqlESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRA 153
Cdd:PRK05980  79 dvalrDFVR---RGQAMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 154 VGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEV 233
Cdd:PRK05980 156 AGRKRALELLLTGDAFSAERALEIGLVNAVVPHEELLPAARALARRIIRHSPVAVAAILTAVTRGLNLSIAEGLLIESEQ 235
                        250       260
                 ....*....|....*....|....*
gi 516959219 234 LFRLYGTADGQEGIDAFLDKRDPVF 258
Cdd:PRK05980 236 FARMAGSADLREGLAAWIERRRPAY 260
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
1-260 3.74e-41

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 142.00  E-value: 3.74e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDlEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEF 80
Cdd:PRK08139   8 TEAPLLLRED-RDGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAG-KAFCAGHDLKEMRAARGLAY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAyQLESR--RVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQrLTRAVGRIV 158
Cdd:PRK08139  86 FR-ALFARcsRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFCSTPMVA-LSRNVPRKQ 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 159 ASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLY 238
Cdd:PRK08139 164 AMEMLLTGEFIDAATAREWGLVNRVVPADALDAAVARLAAVIAAKSPAAVRIGKEAFYRQAEMPLADAYAYAGDVMAENM 243
                        250       260
                 ....*....|....*....|..
gi 516959219 239 GTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK08139 244 MAEDAEEGIDAFLEKRPPEWRG 265
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
18-259 5.97e-41

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 141.33  E-value: 5.97e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  18 LTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAgEKAFVAGADIAEYRGNRRAEfiAYQLESRRVFDKLEAL 97
Cdd:PRK05862  17 ITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITGS-EKAFAAGADIKEMADLSFMD--VYKGDYITNWEKVARI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  98 AKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGERAHQL 177
Cdd:PRK05862  94 RKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAAEAERA 173
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 178 GLAVECVADDALMEMAESRARamlKVAPLAQAEMkRLIRQGPDAAL--PVAQG--FEQEVLFRLYGTADGQEGIDAFLDK 253
Cdd:PRK05862 174 GLVSRVVPADKLLDEALAAAT---TIASFSLPAV-MMAKEAVNRAYetTLAEGllFERRLFHSLFATEDQKEGMAAFVEK 249

                 ....*.
gi 516959219 254 RDPVFK 259
Cdd:PRK05862 250 RKPVFK 255
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
15-260 1.35e-38

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 135.54  E-value: 1.35e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  15 IVRLTFNRPDKLNALSTPLMQEFEAHLDAIAAdPAVRVVIL-AGAGEKAFVAGADIAEYRGNRRaEFIAYQLESRRVFDK 93
Cdd:PRK11423  14 IATITFNNPAKRNALSKVLIDDLMQALSDLNR-PEIRVVILrAPSGSKVWSAGHDIHELPSGGR-DPLSYDDPLRQILRM 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  94 LEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGER 173
Cdd:PRK11423  92 IQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQR 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 174 AHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFE--QEVLFRLYGTADGQEGIDAFL 251
Cdd:PRK11423 172 ALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEQLRVLGEAHPMNPDEFEriQGLRRAVYDSEDYQEGMNAFL 251

                 ....*....
gi 516959219 252 DKRDPVFKG 260
Cdd:PRK11423 252 EKRKPVFVG 260
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
1-260 2.58e-38

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 134.82  E-value: 2.58e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDlePGIVRLTFNRPdKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADI-AEYRGNrrAE 79
Cdd:PRK03580   1 MSESLHTTRN--GSILEITLDRP-KANAIDAKTSFAMGEVFLNFRDDPELRVAIITGAGEKFFSAGWDLkAAAEGE--AP 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  80 FIAYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVA 159
Cdd:PRK03580  76 DADFGPGGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 160 SDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGpdAALPVAQGFEQ------EV 233
Cdd:PRK03580 156 NEMVMTGRRMDAEEALRWGIVNRVVPQAELMDRARELAQQLVNSAPLAIAALKEIYRET--SEMPVEEAYRYirsgvlKH 233
                        250       260
                 ....*....|....*....|....*..
gi 516959219 234 LFRLYGTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK03580 234 YPSVLHSEDALEGPRAFAEKRDPVWKG 260
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
6-260 1.66e-37

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 132.91  E-value: 1.66e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   6 VLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAE-------------- 71
Cdd:PRK06210   7 VLYEVADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAG-RGFCAGADMGElqtidpsdgrrdtd 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  72 ---YRGNRRAEFiayqlESRRVFdkLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQ 148
Cdd:PRK06210  86 vrpFVGNRRPDY-----QTRYHF--LTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISW 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 149 RLTRAVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLK-VAPLAQAEMKRLIRQGPDAALPVAQ 227
Cdd:PRK06210 159 ILPRLVGHANALDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARnVSPASMAVIKRQLYEDAFQTLAEAT 238
                        250       260       270
                 ....*....|....*....|....*....|...
gi 516959219 228 GFEQEVLFRLYGTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK06210 239 ARANREMHESLQRPDFIEGVASFLEKRPPRFPG 271
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
1-260 1.38e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 125.11  E-value: 1.38e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDdlEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRR--A 78
Cdd:PRK07511   1 MSAELLSRR--EGSTLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAG-GFFCAGGNLNRLLENRAkpP 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  79 EFIAYQLES-RRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRI 157
Cdd:PRK07511  78 SVQAASIDGlHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQ 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 158 VASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRL 237
Cdd:PRK07511 158 LATELLLEGKPISAERLHALGVVNRLAEPGQALAEALALADQLAAGSPNALARIKSLIADAPEATLAAQLEAERDHFVAS 237
                        250       260
                 ....*....|....*....|...
gi 516959219 238 YGTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK07511 238 LHHADALEGIAAFLEKRAPDYKR 260
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
14-260 2.44e-34

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 124.40  E-value: 2.44e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEFIAYQLESRRV--- 90
Cdd:PRK07468  14 GVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTADRATRIEEARRLamm 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  91 FDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRaVGRIVASDMMLAARRIT 170
Cdd:PRK07468  93 LKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMSARLFD 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 171 GERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQEGIDAF 250
Cdd:PRK07468 172 AEEAVRLGLLSRVVPAERLDAAVEAEVTPYLSCAPGAVAAAKALVRALGAPIDEAVIDATIEALADTWETEEAREGIAAF 251
                        250
                 ....*....|
gi 516959219 251 LDKRDPVFKG 260
Cdd:PRK07468 252 FDKRAPAWRG 261
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
4-260 2.78e-34

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 124.04  E-value: 2.78e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   4 PLVLRDDLEPGIVRLTFNRPdKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEyRGNRRA---EF 80
Cdd:PRK06495   3 MSQLKLEVSDHVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKG-RPDVIKgpgDL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLtraVGRIVAS 160
Cdd:PRK06495  80 RAHNRRTRECFHAIRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLAGGGKHAMRL---FGHSLTR 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 161 DMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGT 240
Cdd:PRK06495 157 RMMLTGYRVPAAELYRRGVIEACLPPEELMPEAMEIAREIASKSPLATRLAKDALNTIENMSLRDGYRYEQDITAKLAKT 236
                        250       260
                 ....*....|....*....|
gi 516959219 241 ADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK06495 237 EDAKEAQRAFLEKRPPVFKG 256
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
1-260 3.51e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 123.87  E-value: 3.51e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDdLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAiAADPAVRVVILAGAGeKAFVAGADIAE--YRGNRRA 78
Cdd:PRK08140   1 MMYETILLA-IEAGVATLTLNRPDKLNSFTREMHRELREALDQ-VEDDGARALLLTGAG-RGFCAGQDLADrdVTPGGAM 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  79 EFIAYQLES------RRvfdkLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTR 152
Cdd:PRK08140  78 PDLGESIETfynplvRR----LRALPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPR 153
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 153 AVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQE 232
Cdd:PRK08140 154 LVGMARALGLALLGEKLSAEQAEQWGLIWRVVDDAALADEAQQLAAHLATQPTRGLALIKQAMNASATNTLDAQLDLERD 233
                        250       260
                 ....*....|....*....|....*....
gi 516959219 233 vLFRLYG-TADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK08140 234 -LQREAGrSADYAEGVSAFLEKRAPRFTG 261
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
6-254 5.58e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 123.22  E-value: 5.58e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   6 VLRDDlePGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAEFIAYQL 85
Cdd:PRK06143  10 VTRDD--RGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFIS 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  86 ESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQrLTRAVGRIVASDMMLA 165
Cdd:PRK06143  88 RLRDLCDAVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGIPSVIHAAL-LPRLIGWARTRWLLLT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 166 ARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQE 245
Cdd:PRK06143 167 GETIDAAQALAWGLVDRVVPLAELDAAVERLAASLAGCGPQALRQQKRLLREWEDMPLDVAIDDSVAEFGAAFLTGEPQR 246

                 ....*....
gi 516959219 246 GIDAFLDKR 254
Cdd:PRK06143 247 HMAAFLNRK 255
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
7-260 5.70e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 124.35  E-value: 5.70e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   7 LRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADI---AEYRGNRRAEFIAY 83
Cdd:PRK08260   6 IRYDVADGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLsagGNTFDLDAPRTPVE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  84 QLESR--------------RVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQR 149
Cdd:PRK08260  85 ADEEDradpsddgvrdgggRVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWF 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 150 LTRAVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAML-KVAPLAQAEMKRLIRQGPDAALPV-AQ 227
Cdd:PRK08260 165 LPRLVGLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAARALAREIAdNTSPVSVALTRQMMWRMAGADHPMeAH 244
                        250       260       270
                 ....*....|....*....|....*....|...
gi 516959219 228 GFEQEVLFRLYGTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK08260 245 RVDSRAIYSRGRSGDGKEGVSSFLEKRPAVFPG 277
PLN02888 PLN02888
enoyl-CoA hydratase
2-232 8.47e-34

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 122.94  E-value: 8.47e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   2 SEPLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADI--AE--YRGNrr 77
Cdd:PLN02888   7 SENLILVPKSRNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSG-RAFCSGVDLtaAEevFKGD-- 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  78 aefiaYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRI 157
Cdd:PLN02888  84 -----VKDVETDPVAQMERCRKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGAN 158
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 516959219 158 VASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQE 232
Cdd:PLN02888 159 RAREVSLTAMPLTAETAERWGLVNHVVEESELLKKAREVAEAIIKNNQGMVLRYKSVINDGLKLDLGHALQLEKE 233
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
1-232 1.52e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 122.00  E-value: 1.52e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDlEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEF 80
Cdd:PRK06190   1 MTEPILLVET-HDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGAD-PAFCAGLDLKELGGDGSAYG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IayQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVAS 160
Cdd:PRK06190  79 A--QDALPNPSPAWPAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRAR 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 516959219 161 DMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGpdAALPVAQGFEQE 232
Cdd:PRK06190 157 RMSLTGDFLDAADALRAGLVTEVVPHDELLPRARRLAASIAGNNPAAVRALKASYDDG--AAAQTGDALALE 226
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
14-260 9.40e-33

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 120.09  E-value: 9.40e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADI-AEYRGNRRAefiayqLESRRVFD 92
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAG-GTFCAGMDLkAFARGERPS------IPGRGFGG 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  93 KLEA-LAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITG 171
Cdd:PRK08252  85 LTERpPRKPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTA 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 172 ERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQEGIDAFL 251
Cdd:PRK08252 165 ERAHELGLVNRLTEPGQALDAALELAERIAANGPLAVAASKRIVVESGDWSEDEMFARQRELIAPVFTSADAKEGATAFA 244

                 ....*....
gi 516959219 252 DKRDPVFKG 260
Cdd:PRK08252 245 EKRAPVWTG 253
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
18-259 2.99e-32

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 118.87  E-value: 2.99e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  18 LTFNRPDKlNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEY-RGNRRAEFIAyqleSRRVFDKLEA 96
Cdd:PRK09076  16 LTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLNLFaDGDKAVAREM----ARRFGEAFEA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  97 LAK---PTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGER 173
Cdd:PRK09076  91 LSAfrgVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAAT 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 174 AHQLGLAVECV----ADDALMEMAESRARamlkVAPLAQAEMKRLI---RQGP-DAALPVaqgfEQEVLFRLYGTADGQE 245
Cdd:PRK09076 171 ALRIGLVEEVVekgeAREAALALAQKVAN----QSPSAVAACKTLIqaaRNGPrAAALAL----ERELFVDLFDTEDQRE 242
                        250
                 ....*....|....
gi 516959219 246 GIDAFLDKRDPVFK 259
Cdd:PRK09076 243 GVNAFLEKRAPQWK 256
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
18-260 1.91e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 114.04  E-value: 1.91e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  18 LTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEFIAYQLESRRVFDKL--- 94
Cdd:PRK07799  18 VTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAG-GAFCAGMDLKAATKKPPGDSFKDGSYDPSRIDALlkg 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  95 EALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGERA 174
Cdd:PRK07799  97 RRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA 176
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 175 HQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGpdAALPVAQGF--EQEVLFRLYGTADGQEGIDAFLD 252
Cdd:PRK07799 177 KEIGLIGHVVPDGQALDKALELAELINANGPLAVQAILRTIRET--EGMHENEAFkiDTKIGIPVFLSEDAKEGPRAFAE 254

                 ....*...
gi 516959219 253 KRDPVFKG 260
Cdd:PRK07799 255 KRAPNFQG 262
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
1-260 2.53e-30

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 113.91  E-value: 2.53e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDlePGIVRLTFNRPDKLNALSTP-LMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRgNRRAE 79
Cdd:PRK09245   1 MTDFLLVERD--GHIVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAG-TAFSSGGNVKDMR-ARVGA 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  80 FIAYQLESR--------RVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLT 151
Cdd:PRK09245  77 FGGSPADIRqgyrhgiqRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLP 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 152 RAVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAAL-------P 224
Cdd:PRK09245 157 RIIGMARAAEMAFTGDAIDAATALEWGLVSRVVPADQLLPAARALAERIAANPPHALRLTKRLLREGQHASLdtllelsA 236
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 516959219 225 VAQGFEQEvlfrlygTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK09245 237 AYQALAHH-------TADHREAVDAFLEKRPPVFTG 265
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
12-260 3.54e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 113.48  E-value: 3.54e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  12 EPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEFIAYQLESRRVF 91
Cdd:PRK05995  11 RGQVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAG-KAFCAGADLNWMKKMAGYSDDENRADARRLA 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  92 DKLEALA---KPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQrLTRAVGRIVASDMMLAARR 168
Cdd:PRK05995  90 DMLRAIYrcpKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPY-VIRAMGERAARRYFLTAER 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 169 ITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIR----QGPDAALpVAQGFEQEVLFRLygTADGQ 244
Cdd:PRK05995 169 FDAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQAVRAGKRLVRdvagRPIDAAL-IADTASRIALIRA--TEEAR 245
                        250
                 ....*....|....*.
gi 516959219 245 EGIDAFLDKRDPVFKG 260
Cdd:PRK05995 246 EGVAAFLEKRKPAWRG 261
PLN02921 PLN02921
naphthoate synthase
14-258 5.27e-29

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 111.80  E-value: 5.27e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAeYRGNR---------RAEFIAYQ 84
Cdd:PLN02921  76 GIAKITINRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQA-VRGKDgyvgpddagRLNVLDLQ 154
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  85 LESRRvfdkleaLAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMML 164
Cdd:PLN02921 155 IQIRR-------LPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWF 227
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 165 AARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQ-GFEQEVLFrlYGTADG 243
Cdd:PLN02921 228 LARFYTASEALKMGLVNTVVPLDELEGETVKWCREILRNSPTAIRVLKSALNAADDGHAGLQElGGNATLLF--YGSEEG 305
                        250
                 ....*....|....*
gi 516959219 244 QEGIDAFLDKRDPVF 258
Cdd:PLN02921 306 NEGRTAYLEGRAPDF 320
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
5-258 8.25e-29

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 110.31  E-value: 8.25e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   5 LVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGAD------IAEYRGNRRA 78
Cdd:PRK05864  10 LVLVDHPRPEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAG-RGFSSGADhksagvVPHVEGLTRP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  79 efiAYQLESRRVFDK----LEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSAR-LGLPEGLLGLSPGGGGTQRLTRA 153
Cdd:PRK05864  89 ---TYALRSMELLDDvilaLRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYfRAAGINNGLTASELGLSYLLPRA 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 154 VGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAAlPVAQGFEQEV 233
Cdd:PRK05864 166 IGSSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYAIAARMAGFSRPGIELTKRTLWSGLDAA-SLEAHMQAEG 244
                        250       260
                 ....*....|....*....|....*...
gi 516959219 234 LFRLY---GTADGQEGIDAFLDKRDPVF 258
Cdd:PRK05864 245 LGQLFvrlLTANFEEAVAARAEKRPPVF 272
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
10-215 1.33e-28

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 110.13  E-value: 1.33e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  10 DLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAE---------- 79
Cdd:PRK08272  15 EVTGRIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAG-KGFCAGYDLSAYAEGSSSGggggaypgkr 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  80 -------------FIAYQLESR--RVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARlglPEGLLGLSPGG 144
Cdd:PRK08272  94 qavnhlpddpwdpMIDYQMMSRfvRGFMSLWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADDAK---IGYPPTRVWGV 170
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 516959219 145 GGTQRLTRAVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVaPLAQAEMKRLI 215
Cdd:PRK08272 171 PATGMWAYRLGPQRAKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIAAV-PVNQLAMVKLA 240
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
11-260 2.24e-28

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 108.58  E-value: 2.24e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  11 LEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAvRVVILAGAGeKAFVAGADIAEYRGNRRAEfiayqlESRRV 90
Cdd:PRK07659  12 YEGRVATIMLNRPEALNALDEPMLKELLQALKEVAESSA-HIVVLRGNG-RGFSAGGDIKMMLSSNDES------KFDGV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  91 FDKLEALA-------KPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMM 163
Cdd:PRK07659  84 MNTISEIVvtlytmpKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQII 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 164 LAARRITGERAHQLGLAVEcVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADG 243
Cdd:PRK07659 164 WEGKKLSATEALDLGLIDE-VIGGDFQTAAKQKISEWLQKPLKAMIETKQIYCELNRSQLEQVLQLEKRAQYAMRQTADH 242
                        250
                 ....*....|....*..
gi 516959219 244 QEGIDAFLDKRDPVFKG 260
Cdd:PRK07659 243 KEGIRAFLEKRLPVFKG 259
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
11-204 4.91e-28

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 112.26  E-value: 4.91e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  11 LEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAgAGEKAFVAGADIAEYRGN---RRAEFIAYQLES 87
Cdd:PRK11730  13 LEDGIAELVFDAPGSVNKLDRATLASLGEALDALEAQSDLKGLLLT-SAKDAFIVGADITEFLSLfaaPEEELSQWLHFA 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  88 RRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAAR 167
Cdd:PRK11730  92 NSIFNRLEDLPVPTVAAINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGK 171
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 516959219 168 RITGERAHQLGLAVECVADDALMEMAESraraMLKVA 204
Cdd:PRK11730 172 DVRAEDALKVGAVDAVVAPEKLQEAALA----LLKQA 204
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
1-260 5.74e-28

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 107.75  E-value: 5.74e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADI----------- 69
Cdd:PRK06142   2 MTTYESFTVELADHVAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSG-KHFSYGIDLpamagvfgqlg 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  70 AEYRGNRRAEFIAYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQR 149
Cdd:PRK06142  81 KDGLARPRTDLRREILRLQAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQR 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 150 LTRAVGRIVASDMMLAARRITGERAHQLGLAVECVAD-DALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAAlpVAQG 228
Cdd:PRK06142 161 LPRIIGDGHLRELALTGRDIDAAEAEKIGLVNRVYDDaDALLAAAHATAREIAAKSPLAVRGTKEVLDYMRDHR--VADG 238
                        250       260       270
                 ....*....|....*....|....*....|....
gi 516959219 229 FEQEVLFR--LYGTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK06142 239 LRYVATWNaaMLPSKDLTEAIAAHMEKRPPEFTG 272
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
5-199 2.20e-27

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 110.37  E-value: 2.20e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   5 LVLRDDlepGIVRLTFNRPD-KLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADI---AEYRGNRRAEF 80
Cdd:PRK11154   9 LNVRED---NIAVITIDVPGeKMNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADInmlAACKTAQEAEA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAYQleSRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPG--GGGTQRLTRAVGRIV 158
Cdd:PRK11154  86 LARQ--GQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTVLGLPEVQLGLLpgSGGTQRLPRLIGVST 163
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 516959219 159 ASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARA 199
Cdd:PRK11154 164 ALDMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAKK 204
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
10-254 2.59e-27

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 106.25  E-value: 2.59e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  10 DLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEkAFVAGADIAEYRGNRRAEFIAYQLESRR 89
Cdd:PRK09120  13 EVEDGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGD-AWSAGMDLKEYFRETDAQPEILQERIRR 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  90 V----FDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLA 165
Cdd:PRK09120  92 EaygwWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMT 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 166 ARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGF---EQEVLFRLYGTAD 242
Cdd:PRK09120 172 GETFTGRKAAEMGLVNESVPLAQLRARTRELAAKLLEKNPVVLRAAKDGFKRVRELTWDQAEDYlyaKLEQANSLDPEGG 251
                        250
                 ....*....|..
gi 516959219 243 GQEGIDAFLDKR 254
Cdd:PRK09120 252 REEGLKQFLDDK 263
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
14-261 4.29e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 102.16  E-value: 4.29e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNrraefIAYQLES--RRVF 91
Cdd:PRK06072   9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPD-----FAIDLREtfYPII 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  92 DKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGrIVASDMMLAARRITG 171
Cdd:PRK06072  83 REIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTG-QRFYEILVLGGEFTA 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 172 ERAHQLGlavecvaddaLMEMAESraramlkvaPLAQA-EMKRLIRQGPDAALPVAQGFEQEVLF--------------- 235
Cdd:PRK06072 162 EEAERWG----------LLKISED---------PLSDAeEMANRISNGPFQSYIAAKRMINLVLYndleefleyesaiqg 222
                        250       260
                 ....*....|....*....|....*.
gi 516959219 236 RLYGTADGQEGIDAFLDKRDPVFKGI 261
Cdd:PRK06072 223 YLGKTEDFKEGISSFKEKREPKFKGI 248
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
14-259 8.49e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 101.88  E-value: 8.49e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEyrgnrraeFIAYQLESRRVFDK 93
Cdd:PRK07509  12 GIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEG-GAFCAGLDVKS--------VASSPGNAVKLLFK 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  94 L---------------EALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIV 158
Cdd:PRK07509  83 RlpgnanlaqrvslgwRRLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDV 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 159 ASDMMLAARRITGERAHQLGLAVECVADDalMEMAESRARAMLKVAPLAQAEMKRLIRQ---GPDAALPVAQGFEQEvlf 235
Cdd:PRK07509 163 ARELTYTARVFSAEEALELGLVTHVSDDP--LAAALALAREIAQRSPDAIAAAKRLINRswtASVRALLARESVEQI--- 237
                        250       260
                 ....*....|....*....|....
gi 516959219 236 RLYGTADGQEGIDAFLDKRDPVFK 259
Cdd:PRK07509 238 RLLLGKNQKIAVKAQMKKRAPKFL 261
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
10-260 3.17e-25

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 100.58  E-value: 3.17e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  10 DLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPA-VRVVILAGAGeKAFVAGADIAEyRGNRRAEFIAYQ---- 84
Cdd:PRK05981   9 DFDGGVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKAeVRCLVLTGAG-RGFCTGANLQG-RGSGGRESDSGGdaga 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  85 -LES--RRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASD 161
Cdd:PRK05981  87 aLETayHPFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAME 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 162 MMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTA 241
Cdd:PRK05981 167 LSLLGEKLPAETALQWGLVNRVVDDAELMAEAMKLAHELANGPTVALGLIRKLYWDSPENDFEEQLNLEREAQRIAGKTE 246
                        250
                 ....*....|....*....
gi 516959219 242 DGQEGIDAFLDKRDPVFKG 260
Cdd:PRK05981 247 DFKEGVGAFLQKRPAQFKG 265
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
18-260 4.79e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 99.65  E-value: 4.79e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  18 LTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKaFVAG---ADIAEYRGNRRAEFIAYQLESRRVFDKl 94
Cdd:PRK06563  12 IGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEH-FTAGldlADVAPKLAAGGFPFPEGGIDPWGTVGR- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  95 eALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGERA 174
Cdd:PRK06563  90 -RLSKPLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFDAQEA 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 175 HQLGLAVECVADDALMEMAESRARAMLKVAPLA-QAEMK--RL-IRQGPDAALpvAQgfEQEVLFRLYGTADGQEGIDAF 250
Cdd:PRK06563 169 LRLGLVQEVVPPGEQLERAIELAERIARAAPLGvQATLAsaRAaVREGEAAAA--AQ--LPPELRPLFTSEDAKEGVQAF 244
                        250
                 ....*....|
gi 516959219 251 LDKRDPVFKG 260
Cdd:PRK06563 245 LERRPARFKG 254
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
14-256 2.38e-24

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 97.96  E-value: 2.38e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEFIAYQLESRRVFDK 93
Cdd:PRK05674  15 GFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGADLAWMQQSADLDYNTNLDDARELAEL 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  94 LEALAK---PTIAAIRGYALGGGFEIALCCDVIVCATSARlGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRIT 170
Cdd:PRK05674  94 MYNLYRlkiPTLAVVQGAAFGGALGLISCCDMAIGADDAQ-FCLSEVRIGLAPAVISPFVVKAIGERAARRYALTAERFD 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 171 GERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAAL-PVAQGFEQEVLFRLYGTADGQEGIDA 249
Cdd:PRK05674 173 GRRARELGLLAESYPAAELEAQVEAWIANLLLNSPQALRASKDLLREVGDGELsPALRRYCENAIARIRVSAEGQEGLRA 252

                 ....*..
gi 516959219 250 FLDKRDP 256
Cdd:PRK05674 253 FLEKRTP 259
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
1-199 7.50e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 96.33  E-value: 7.50e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLrdDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGnrrAEF 80
Cdd:PRK05870   1 MMDPVLL--DVDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAG-KAFCAGADLTALGA---APG 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAYQLESRRVFDKLEALAK---PTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRI 157
Cdd:PRK05870  75 RPAEDGLRRIYDGFLAVAScplPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQ 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 516959219 158 VASDMMLAARRITGERAHQLGLAVECVAD--DALMEMAESRARA 199
Cdd:PRK05870 155 VARAALLFGMRFDAEAAVRHGLALMVADDpvAAALELAAGPAAA 198
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
6-258 4.09e-23

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 94.97  E-value: 4.09e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   6 VLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEY-----------RG 74
Cdd:PLN02664   9 IIQKSPNSSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAG-DHFCSGIDLKTLnsiseqsssgdRG 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  75 nRRAEFIAYQLES-RRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRA 153
Cdd:PLN02664  88 -RSGERLRRKIKFlQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSI 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 154 VGRIVASDMMLAARRITGERAHQLGLAVECVA-DDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDaaLPVAQGFEQE 232
Cdd:PLN02664 167 VGYGNAMELALTGRRFSGSEAKELGLVSRVFGsKEDLDEGVRLIAEGIAAKSPLAVTGTKAVLLRSRE--LSVEQGLDYV 244
                        250       260
                 ....*....|....*....|....*...
gi 516959219 233 VLFR--LYGTADGQEGIDAFLDKRDPVF 258
Cdd:PLN02664 245 ATWNsaMLVSDDLNEAVSAQIQKRKPVF 272
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
12-260 1.26e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 92.78  E-value: 1.26e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  12 EPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAiAADPAVRVVILAGAGeKAFVAGADIAEyrGNRRAEFiayqleSRRVF 91
Cdd:PRK07854   7 DGQVLTIELQRPERRNALNAELCEELREAVRK-AVDESARAIVLTGQG-TVFCAGADLSG--DVYADDF------PDALI 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  92 DKLEALAK---PTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARR 168
Cdd:PRK07854  77 EMLHAIDAapvPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEK 156
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 169 ITGERAHQLGLAVECVADDALMEMAESRARamlkVAPLAQAEMKRLIRQ--GPDAALPVaqgfEQEVLFRLYGTADGQEG 246
Cdd:PRK07854 157 LTAEQALATGMANRIGTLADAQAWAAEIAG----LAPLALQHAKRVLNDdgAIEEAWPA----HKELFDKAWASQDAIEA 228
                        250
                 ....*....|....
gi 516959219 247 IDAFLDKRDPVFKG 260
Cdd:PRK07854 229 QVARIEKRPPKFQG 242
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
1-256 6.07e-22

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 91.67  E-value: 6.07e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVlRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEF 80
Cdd:PRK07827   3 PVDTLV-RYAVDGGVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVLTHTG-GTFCAGADLSEAGGGGGDPY 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAYQLESRRVFDKLEA---LAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRi 157
Cdd:PRK07827  81 DAAVARAREMTALLRAiveLPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPR- 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 158 VASDMMLAARRITGERAHQLGLAVECVAD--DALMEMAESRARAmlkvAPLAQAEMKRLIRQgpdaalPVAQGFEQ---- 231
Cdd:PRK07827 160 AAARYYLTGEKFGAAEAARIGLVTAAADDvdAAVAALLADLRRG----SPQGLAESKALTTA------AVLAGFDRdaee 229
                        250       260
                 ....*....|....*....|....*..
gi 516959219 232 --EVLFRLYGTADGQEGIDAFLDKRDP 256
Cdd:PRK07827 230 ltEESARLFVSDEAREGMTAFLQKRPP 256
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
6-229 1.65e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 90.79  E-value: 1.65e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   6 VLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAE-------------- 71
Cdd:PRK08290   5 YVRYEVAGRIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAG-KHFSAGHDLGSgtpgrdrdpgpdqh 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  72 ------YRGNRRAEFIaYQLESRRVFD---KLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSP 142
Cdd:PRK08290  84 ptlwwdGATKPGVEQR-YAREWEVYLGmcrRWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGIPG 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 143 GGGGTQrlTRAVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDaa 222
Cdd:PRK08290 163 VEYFAH--PWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRDELEAETLELARRIAAMPPFGLRLTKRAVNQTLD-- 238

                 ....*..
gi 516959219 223 lpvAQGF 229
Cdd:PRK08290 239 ---AQGF 242
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
10-179 2.64e-21

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 92.98  E-value: 2.64e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   10 DLEPGIVRLTFNRPD-KLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAEfIAYQL--E 86
Cdd:TIGR02441  18 EVKGDVAVVKIDSPNsKVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQ-EVTQLsqE 96
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   87 SRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVcATSARLGLPEGLLGLSPG---GGGTQRLTRAVGRIVASDMM 163
Cdd:TIGR02441  97 GQEMFERIEKSQKPIVAAISGSCLGGGLELALACHYRI-ATKDRKTLLGLPEVMLGLlpgAGGTQRLPKLTGVPAALDMM 175
                         170
                  ....*....|....*.
gi 516959219  164 LAARRITGERAHQLGL 179
Cdd:TIGR02441 176 LTGKKIRADRAKKMGI 191
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
4-207 8.30e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 88.15  E-value: 8.30e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   4 PLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADpaVRVVILAGAGEKaFVAGADIAEYRGNRRAEFIAY 83
Cdd:PRK08150   1 PSLVSYELDGGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHH 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  84 QLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMM 163
Cdd:PRK08150  78 SRRWHRVFDKIQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMM 157
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 516959219 164 LAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLA 207
Cdd:PRK08150 158 LTGRVYDAQEGERLGLAQYLVPAGEALDKAMELARRIAQNAPLT 201
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
9-260 1.43e-20

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 87.77  E-value: 1.43e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   9 DDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGAD---IAEYRGNRRAEFIAYQl 85
Cdd:PRK07327  16 DRPPPGVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEG-KAFSAGGDlalVEEMADDFEVRARVWR- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  86 ESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGllglspggggtqRLTRAVG---RIV---- 158
Cdd:PRK07327  94 EARDLVYNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHT------------RLGVAAGdhaAIVwpll 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 159 -----ASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVaqgFEQEV 233
Cdd:PRK07327 162 cgmakAKYYLLLCEPVSGEEAERIGLVSLAVDDDELLPKALEVAERLAAGSQTAIRWTKYALNNWLRMAGPT---FDTSL 238
                        250       260
                 ....*....|....*....|....*....
gi 516959219 234 LFRLYGTA--DGQEGIDAFLDKRDPVFKG 260
Cdd:PRK07327 239 ALEFMGFSgpDVREGLASLREKRAPDFPG 267
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
9-212 2.07e-19

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 83.74  E-value: 2.07e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   9 DDLEPGIVRLTFNRPDKlNALSTPLMQEFEAHLDAIAADPAVRVVILAGaGEKAFVAGADIAEYRGNRRAEFIAYQLESR 88
Cdd:PRK05869  12 GSQDAGLATLLLSRPPT-NALTRQVYREIVAAANELGRRDDVAAVILYG-GHEIFSAGDDMPELRTLSAQEADTAARVRQ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  89 RVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARR 168
Cdd:PRK05869  90 QAVDAVAAIPKPTVAAITGYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRF 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 516959219 169 ITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMK 212
Cdd:PRK05869 170 FDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDGPPHALAAAK 213
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
14-259 2.99e-19

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 84.56  E-value: 2.99e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLTFNRPDKLNALsTPLM-QEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADiAEYRGN---------RRAEFIAY 83
Cdd:PRK07396  22 GIAKITINRPEVRNAF-RPKTvKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGD-QKVRGYggyvdddgvPRLNVLDL 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  84 QLESRRvfdkleaLAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMM 163
Cdd:PRK07396 100 QRLIRT-------CPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIW 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 164 LAARRITGERAHQLGLaVECVADDALMEMAESR-ARAMLKVAPLAQaemkRLIRQGPDAALPVAQGFEQ-----EVLFrl 237
Cdd:PRK07396 173 FLCRQYDAQEALDMGL-VNTVVPLADLEKETVRwCREMLQNSPMAL----RCLKAALNADCDGQAGLQElagnaTMLF-- 245
                        250       260
                 ....*....|....*....|..
gi 516959219 238 YGTADGQEGIDAFLDKRDPVFK 259
Cdd:PRK07396 246 YMTEEAQEGRNAFNEKRQPDFS 267
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
7-217 4.85e-19

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 84.16  E-value: 4.85e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   7 LRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEK-AFVAGADIAEYRG-----NRRAEF 80
Cdd:PLN03214  13 VRVDRRPGGIAVVWLAKEPVNSMTLAMWRSLDDALTALENDPTVRGVVFASGLRRdVFTAGNDIAELYApktsaARYAEF 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAYQ-------LESRRVfdklealakpTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLT-R 152
Cdd:PLN03214  93 WLTQttflvrlLRSRLA----------TVCAIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIPVPKFWARLFMgR 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 516959219 153 AVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQ 217
Cdd:PLN03214 163 VIDRKVAESLLLRGRLVRPAEAKQLGLIDEVVPAAALMEAAASAMERALKLPSAARAATKALLRE 227
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
1-234 2.09e-18

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 81.55  E-value: 2.09e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   1 MSEPLVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEkAFVAGADiaeyrgnrrAEF 80
Cdd:PRK07110   1 MMMKVVELREVEEGIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPN-YFATGGT---------QEG 70
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  81 IAYQLESRRVF--DKLEALAK----PTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAV 154
Cdd:PRK07110  71 LLSLQTGKGTFteANLYSLALncpiPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKL 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 155 GRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAqgFEQEVL 234
Cdd:PRK07110 151 GLALGQEMLLTARYYRGAELKKRGVPFPVLPRAEVLEKALELARSLAEKPRHSLVLLKDHLVADRRRRLPEV--IEQEVA 228
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
12-259 2.66e-18

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 82.38  E-value: 2.66e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  12 EPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAG--EK----AFVAGADIA-------EYRGNRRA 78
Cdd:PRK08321  32 DQGTVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTGNGpsPKdggwAFCSGGDQRirgrdgyQYAEGDEA 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  79 EFI-------AYQLESRRVfdkLEALAKPTIAAIRGYALGGGFEIALCCDV-IVCATSARLGLPEGLLGLSPGGGGTQRL 150
Cdd:PRK08321 112 DTVdparagrLHILEVQRL---IRFMPKVVIAVVPGWAAGGGHSLHVVCDLtLASREHARFKQTDADVGSFDGGYGSAYL 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 151 TRAVGRIVASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQaemkRLIRQG---PDAALPVAQ 227
Cdd:PRK08321 189 ARQVGQKFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETEALEWAREINGKSPTAM----RMLKYAfnlTDDGLVGQQ 264
                        250       260       270
                 ....*....|....*....|....*....|..
gi 516959219 228 GFEQEVLFRLYGTADGQEGIDAFLDKRDPVFK 259
Cdd:PRK08321 265 LFAGEATRLAYMTDEAQEGRDAFLEKRDPDWS 296
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
12-256 3.75e-17

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 78.09  E-value: 3.75e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  12 EPGIVRLTFNRPdKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRgnRRAEFIAYQLESRRVF 91
Cdd:PRK07938   9 EPGIAEVTVDYP-PVNALPSAGWFALADAITAAGADPDTRVVVLRAEG-RGFNAGVDIKELQ--ATPGFTALIDANRGCF 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  92 DKLEAL---AKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLtraVGRIVASDMMLAARR 168
Cdd:PRK07938  85 AAFRAVyecAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPEVDRGALGAATHLQRL---VPQHLMRALFFTAAT 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 169 ITGERAHQLGLAVECVADDALMEMAesraramLKVAPLAQAEMKRLIRQGPDAALPVAQG-------FEQEVLFRLYGTA 241
Cdd:PRK07938 162 ITAAELHHFGSVEEVVPRDQLDEAA-------LEVARKIAAKDTRVIRAAKEALNGIDPQdversyrWEQGFTFELNLAG 234
                        250
                 ....*....|....*
gi 516959219 242 DGQEGIDAFLDKRDP 256
Cdd:PRK07938 235 VSDEHRDAFVEKRKA 249
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
17-113 4.02e-17

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 79.44  E-value: 4.02e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   17 RLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADIAEYRGNRRAEfiayQLESRRVFDKLE- 95
Cdd:pfam16113   3 VITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAAKAG----GGEAGRDFFREEy 78
                          90       100
                  ....*....|....*....|....*
gi 516959219   96 ----ALA---KPTIAAIRGYALGGG 113
Cdd:pfam16113  79 rlnyLIAtypKPYVALMDGIVMGGG 103
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
18-198 6.50e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 77.63  E-value: 6.50e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  18 LTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEkAFVAGAD---IAEYRGNRraefiayqLE-------- 86
Cdd:PRK08259  16 VILNRPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGG-TFCAGADlkaVGTGRGNR--------LHpsgdgpmg 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  87 -SRRVfdkleaLAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLA 165
Cdd:PRK08259  87 pSRMR------LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDLILT 160
                        170       180       190
                 ....*....|....*....|....*....|...
gi 516959219 166 ARRITGERAHQLGLAVECVADDALMEMAESRAR 198
Cdd:PRK08259 161 GRPVDADEALAIGLANRVVPKGQARAAAEELAA 193
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
11-260 9.95e-16

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 74.62  E-value: 9.95e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  11 LEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEkAFVAGAD----IAEYRGNRRAEFIAYQLE 86
Cdd:PRK08258  23 VDDGVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGG-NFCSGGDvheiIGPLTKMDMPELLAFTRM 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  87 SRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARlglpegllglspggggTQRLTRAVG----------- 155
Cdd:PRK08258 102 TGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAK----------------TAFLFTRVGlagadmgacal 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 156 --RIV----ASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQgpDAALPVAQGF 229
Cdd:PRK08258 166 lpRIIgqgrASELLYTGRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAAGPTFAHGMTKTMLHQ--EWDMGLEEAI 243
                        250       260       270
                 ....*....|....*....|....*....|...
gi 516959219 230 EQEVLFR--LYGTADGQEGIDAFLDKRDPVFKG 260
Cdd:PRK08258 244 EAEAQAQaiCMQTEDFRRAYEAFVAKRKPVFEG 276
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
7-215 2.06e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 71.52  E-value: 2.06e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   7 LRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGAD------------IAEYR- 73
Cdd:PRK12478   7 LLYTTAGPVATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGYDfgggfqhwgeamMTDGRw 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  74 --GNRRAEFIAYQLESRRVFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLL-GLSPGGGGTQRL 150
Cdd:PRK12478  86 dpGKDFAMVTARETGPTQKFMAIWRASKPVIAQVHGWCVGGASDYALCADIVIASDDAVIGTPYSRMwGAYLTGMWLYRL 165
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 516959219 151 TRAvgriVASDMMLAARRITGERAHQLGLAVECVADDAL-MEMAESRARamLKVAPLAQAEMKRLI 215
Cdd:PRK12478 166 SLA----KVKWHSLTGRPLTGVQAAEAELINEAVPFERLeARVAEVATE--LARIPLSQLQAQKLI 225
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
14-116 2.74e-12

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 65.61  E-value: 2.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  14 GIVRLtfNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGEKAFVAGADI-----AEYRGNR--RAEFIA--YQ 84
Cdd:PRK05617  14 GVITL--NRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIralyeAARAGDPlaADRFFReeYR 91
                         90       100       110
                 ....*....|....*....|....*....|..
gi 516959219  85 LESRrvfdkLEALAKPTIAAIRGYALGGGFEI 116
Cdd:PRK05617  92 LNAL-----IARYPKPYIALMDGIVMGGGVGI 118
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
10-254 1.44e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 62.83  E-value: 1.44e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  10 DLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNRRAEFIAYQLESRR 89
Cdd:PRK07260   7 EVEDDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANG-KVFSVGGDLVEMKRAVDEDDVQSLVKIAE 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  90 VFDK----LEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLA 165
Cdd:PRK07260  86 LVNEisfaIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLAMT 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 166 ARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIRQGPDAALPVAQGFEQEVLFRLYGTADGQE 245
Cdd:PRK07260 166 GEALTAEKALEYGFVYRVAESEKLEKTCEQLLKKLRRGSSNSYAAIKSLVWESFFKGWEDYAKLELALQESLAFKEDFKE 245

                 ....*....
gi 516959219 246 GIDAFLDKR 254
Cdd:PRK07260 246 GVRAFSERR 254
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
5-216 6.65e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 60.96  E-value: 6.65e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   5 LVLRDDLEPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAgEKAFVAGADIaeyrgnrrAEFIAYQ 84
Cdd:PRK06023   6 LVERPGAHPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGT-EGCFSAGNDM--------QDFLAAA 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  85 LESR----RVFDKLEALA---KPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRI 157
Cdd:PRK06023  77 MGGTsfgsEILDFLIALAeaeKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQ 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 516959219 158 VASDMMLAARRITGERAHQLGLAVECVADDALMEMAESRARAMLKVAPLAQAEMKRLIR 216
Cdd:PRK06023 157 RAFALLALGEGFSAEAAQEAGLIWKIVDEEAVEAETLKAAEELAAKPPQALQIARDLMR 215
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
30-223 5.99e-09

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 55.30  E-value: 5.99e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  30 STPLMQEFEAHLDAI-----AADPAVRVVILAGAGEKAFVAGADIAEY----RGNRRAEFIAYqleSRRVFDKLEALAKP 100
Cdd:PRK08788  41 NLELLDDIMNLQRAIrqrldDSGLPVDFWVLASDVPGVFNLGGDLALFaeliRAGDRDALLAY---ARACVDGVHAFHRG 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219 101 ------TIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTQRLTRAVGRIVASDMMLAARRITGERA 174
Cdd:PRK08788 118 fgagaiSIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEEL 197
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 516959219 175 HQLGLaVECVADDALMEMA-------ESR----ARAMLK----VAPLAQAEMKRLIRQGPDAAL 223
Cdd:PRK08788 198 HDMGL-VDVLVEDGQGEAAvrtfirkSKRklngWRAMLRarrrVNPLSLEELMDITEIWVDAAL 260
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
3-113 3.80e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 50.57  E-value: 3.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219   3 EPLVLRDdlEPGIVRL-TFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEYRGNR----- 76
Cdd:PLN02874  10 EEVVLGE--EKGRVRViTLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLKMFYDGResdds 86
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 516959219  77 ------RAEFIAYQLESRRvfdklealaKPTIAAIRGYALGGG 113
Cdd:PLN02874  87 clevvyRMYWLCYHIHTYK---------KTQVALVHGLVMGGG 120
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
20-118 9.38e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 49.21  E-value: 9.38e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  20 FNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADI---AEYRGNRRAEfiayqlESRRVFDKLEA 96
Cdd:PLN02851  57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADVvslYHLINEGNVE------ECKLFFENLYK 129
                         90       100
                 ....*....|....*....|....*....
gi 516959219  97 LA-------KPTIAAIRGYALGGGFEIAL 118
Cdd:PLN02851 130 FVylqgtylKPNVAIMDGITMGCGAGISI 158
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
18-118 1.20e-05

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 45.86  E-value: 1.20e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  18 LTFNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAEY-----RGNRR--AEFIAYQLESRRV 90
Cdd:PLN02988  22 LTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVvrdieQGNWRlgANFFSDEYMLNYV 100
                         90       100
                 ....*....|....*....|....*...
gi 516959219  91 fdkLEALAKPTIAAIRGYALGGGFEIAL 118
Cdd:PLN02988 101 ---MATYSKAQVSILNGIVMGGGAGVSV 125
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
12-204 3.28e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 43.90  E-value: 3.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  12 EPGIVRLTFNRPDKLNALSTPLMQEFEAHLDAIAADpaVRVVILAGAGEkAFVAGADIAE-YRGNRRAEFIAYQLES-RR 89
Cdd:PRK07112  11 QGDVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHA--ATIVVLEGLPE-VFCFGADFSAiAEKPDAGRADLIDAEPlYD 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  90 VFDKLEALAKPTIAAIRGYALGGGFEIALCCDVIVCATSARLGLPEGLLGLSPGGGGTqRLTRAVGRIVASDMMLAARRI 169
Cdd:PRK07112  88 LWHRLATGPYVTIAHVRGKVNAGGIGFVAASDIVIADETAPFSLSELLFGLIPACVLP-FLIRRIGTQKAHYMTLMTQPV 166
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 516959219 170 TGERAHQLGLAVECVAD-DALMEMAESRARAMLKVA 204
Cdd:PRK07112 167 TAQQAFSWGLVDAYGANsDTLLRKHLLRLRCLNKAA 202
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
20-118 5.94e-04

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 40.82  E-value: 5.94e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 516959219  20 FNRPDKLNALSTPLMQEFEAHLDAIAADPAVRVVILAGAGeKAFVAGADIAE-YRGNRRAEFIAYqlesRRVFDKLEALA 98
Cdd:PLN02157  52 LNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSlYHLRKRGSPDAI----REFFSSLYSFI 126
                         90       100
                 ....*....|....*....|....*..
gi 516959219  99 -------KPTIAAIRGYALGGGFEIAL 118
Cdd:PLN02157 127 yllgtylKPHVAILNGVTMGGGTGVSI 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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