|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
2-1035 |
0e+00 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 1138.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 2 GVSEPFIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMN 81
Cdd:PRK10503 11 GPSRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 82 STSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADTL 161
Cdd:PRK10503 91 SQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 162 LAQRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADAY 241
Cdd:PRK10503 171 VAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEY 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 242 KPVIIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIVS 321
Cdd:PRK10503 251 RQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLS 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 322 DRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVD 401
Cdd:PRK10503 331 DRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVD 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 402 DAIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLTL 481
Cdd:PRK10503 411 DAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTL 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 482 TPMMCSRLLKHAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTASI 561
Cdd:PRK10503 491 TPMMCARMLSQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGII 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 562 TAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERRDDVSVVITRLKGRVAA 641
Cdd:PRK10503 571 QGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVAK 650
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 642 IPGMTVYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQL 721
Cdd:PRK10503 651 VPGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRL 730
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 722 GVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLpgaasatAGAPNAQVPLSAVATLTRTTA 801
Cdd:PRK10503 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRL-------TSSDGGVVPLSSIATIEQRFG 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 802 PLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLGV 881
Cdd:PRK10503 804 PLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGV 883
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 882 LYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAERGQGMSPNEAIVQACLL 961
Cdd:PRK10503 884 LYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLL 963
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517268981 962 RFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRINRRLEQALPPAE 1035
Cdd:PRK10503 964 RFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFPRHE 1037
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1022 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 1104.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 4 SEPFIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNST 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 84 SSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADTLLA 163
Cdd:NF033617 81 SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 164 QRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADAYKP 243
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 244 VIIAYR-NGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIVSD 322
Cdd:NF033617 241 LVIKYAdNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 323 RTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDD 402
Cdd:NF033617 321 RTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 403 AIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLTLT 482
Cdd:NF033617 401 AIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 483 PMMCSRLLKHAHEElavPGLA-AVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTASI 561
Cdd:NF033617 481 PMMCSRLLKANEKP---GRFArAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 562 TAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSvNPTTNVGRLVMTLKPRGERRDDVSVVITRLKGRVAA 641
Cdd:NF033617 558 FGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGG-NPGDNTGFGIINLKPWDERDVSAQEIIDRLRPKLAK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 642 IPGMTVYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQL 721
Cdd:NF033617 637 VPGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARL 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 722 GVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAASatagapnAQVPLSAVATLTRTTA 801
Cdd:NF033617 717 GISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDG-------KLVPLSTLAKIEERAA 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 802 PLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIeMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLGV 881
Cdd:NF033617 790 PLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAI 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 882 LYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAERGQGMSPNEAIVQACLL 961
Cdd:NF033617 869 QYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRREAIYQAAAL 948
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517268981 962 RFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDR 1022
Cdd:NF033617 949 RLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1027 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1090.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 1 MGVSEPFIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 81 NSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLpYPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADT 160
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDV-EPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 161 LLAQRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADA 240
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 241 YKPVIIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIV 320
Cdd:COG0841 240 FENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 321 SDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVV 400
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 401 DDAIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLT 480
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 481 LTPMMCSRLLKHAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTAS 560
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQ 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 561 ITAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERRDDVSVVITRLKGRVA 640
Cdd:COG0841 560 IIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRSADEIIARLREKLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 641 AIPGMTVYFQPVQDvqiSTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQ 720
Cdd:COG0841 640 KIPGARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAA 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 721 LGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAAsatagapNAQVPLSAVATLTRTT 800
Cdd:COG0841 717 LGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPD-------GEMVPLSSVATIEEGT 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 801 APLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLG 880
Cdd:COG0841 790 GPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLA 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 881 VLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFAlEAERGQGMSPNEAIVQACL 960
Cdd:COG0841 870 AQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFA-NQLREEGMSLREAILEAAR 948
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517268981 961 LRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRINRRL 1027
Cdd:COG0841 949 LRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
7-1021 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 906.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTSSF 86
Cdd:pfam00873 5 FIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSSQSSY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 87 GVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLpYPPTYAKVNPADAPVMTLALRSDTISLRAM--SDIADTLLAQ 164
Cdd:pfam00873 85 GLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGV-QRPGISVIKTSLGPIMVLAVTSPDGSYTQTdlRDYADTNIKP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 165 RLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADAYKPV 244
Cdd:pfam00873 164 QLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDFEKI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 245 IIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIVSDRT 324
Cdd:pfam00873 244 IVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVVYDTT 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 325 VTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAI 404
Cdd:pfam00873 324 PFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAI 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 405 VMIENIVRHM-ENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLTLTP 483
Cdd:pfam00873 404 VVVENIERVLeENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLTP 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 484 MMCSRLLKHAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTASITA 563
Cdd:pfam00873 484 ALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVT 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 564 VTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAG--SVNPTTNVGRLVMTLKPRGERR---DDVSVVITRLKGR 638
Cdd:pfam00873 564 SAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAfsGDNNGPNSGDAFISLKPWKERPgpeKSVQALIERLRKA 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 639 VAAIPGMTVYFQPVQDVQISTQSS--RSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRT 716
Cdd:pfam00873 644 LKQIPGANVFLFQPIQLRGLGTISgfRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVNIDRE 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 717 RAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPgaaSATAGApnaqVPLSAVATL 796
Cdd:pfam00873 724 KAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR---NPYGKM----IPLSAFAKI 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 797 TRTTAPLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIY 876
Cdd:pfam00873 797 EWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVF 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 877 IVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAERGQGMSPNEAIV 956
Cdd:pfam00873 877 LVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKSLEEAIL 956
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517268981 957 QACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALD 1021
Cdd:pfam00873 957 EACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
7-1034 |
1.94e-147 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 467.28 E-value: 1.94e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTS-S 85
Cdd:TIGR00915 5 FIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 86 FGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYppTYAKVNPA-DAPVMTLALRSDTISLRA--MSDIADTLL 162
Cdd:TIGR00915 85 DGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQR--QGVRVEKAsSNFLMVIGLVSDDGSMTKedLSDYAASNM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 163 AQRLSQISGVGRVSVLGGLKpAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSL------DGAQQSYIIAANDQIA 236
Cdd:TIGR00915 163 VDPLSRLEGVGDVQLFGSQY-AMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLgglpavPGQQLNATIIAQTRLQ 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 237 AADAYKPVII-AYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGV 315
Cdd:TIGR00915 242 TPEQFENILLkVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQGM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 316 NLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIG 395
Cdd:TIGR00915 322 KYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 396 TGFVVDDAIVMIENIVRHM-ENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTS 474
Cdd:TIGR00915 402 IGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 475 AVVSLTLTPMMCSRLLK----HAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPK 550
Cdd:TIGR00915 482 VLVALILTPALCATMLKpiekGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPT 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 551 GFLPLQDTASITAVTEAGPDVSFAEMQKRQAEAADAIKADP--DVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERR--- 625
Cdd:TIGR00915 562 SFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEkaNVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTgke 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 626 DDVSVVITRLKGRVAAIP-GMTVYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQE 704
Cdd:TIGR00915 642 NSVFAIAGRATGHFMQIKdAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGLE 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 705 GGLRAQLTVDRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAASatagap 784
Cdd:TIGR00915 722 DEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASG------ 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 785 nAQVPLSAVATLTRTTAPLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETriEMPNSIVGVYAGDAAEFAKALAGQ 864
Cdd:TIGR00915 796 -EMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQ--KLPPGFGFSWTGMSYEERLSGSQA 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 865 PWLLLAAVITIYIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAe 944
Cdd:TIGR00915 873 PALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKEL- 951
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 945 RGQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRIN 1024
Cdd:TIGR00915 952 MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLF 1031
|
1050
....*....|
gi 517268981 1025 RRLEQALPPA 1034
Cdd:TIGR00915 1032 KRKAHEKEMS 1041
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
2-1035 |
0e+00 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 1138.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 2 GVSEPFIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMN 81
Cdd:PRK10503 11 GPSRLFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 82 STSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADTL 161
Cdd:PRK10503 91 SQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETR 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 162 LAQRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADAY 241
Cdd:PRK10503 171 VAQKISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEY 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 242 KPVIIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIVS 321
Cdd:PRK10503 251 RQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLS 330
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 322 DRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVD 401
Cdd:PRK10503 331 DRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVD 410
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 402 DAIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLTL 481
Cdd:PRK10503 411 DAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTL 490
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 482 TPMMCSRLLKHAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTASI 561
Cdd:PRK10503 491 TPMMCARMLSQESLRKQNRFSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGII 570
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 562 TAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERRDDVSVVITRLKGRVAA 641
Cdd:PRK10503 571 QGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVAK 650
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 642 IPGMTVYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQL 721
Cdd:PRK10503 651 VPGVDLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRL 730
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 722 GVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLpgaasatAGAPNAQVPLSAVATLTRTTA 801
Cdd:PRK10503 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRL-------TSSDGGVVPLSSIATIEQRFG 803
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 802 PLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLGV 881
Cdd:PRK10503 804 PLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGV 883
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 882 LYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAERGQGMSPNEAIVQACLL 961
Cdd:PRK10503 884 LYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLL 963
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517268981 962 RFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRINRRLEQALPPAE 1035
Cdd:PRK10503 964 RFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFPRHE 1037
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1022 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 1104.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 4 SEPFIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNST 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 84 SSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADTLLA 163
Cdd:NF033617 81 SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 164 QRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADAYKP 243
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 244 VIIAYR-NGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIVSD 322
Cdd:NF033617 241 LVIKYAdNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 323 RTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDD 402
Cdd:NF033617 321 RTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 403 AIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLTLT 482
Cdd:NF033617 401 AIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 483 PMMCSRLLKHAHEElavPGLA-AVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTASI 561
Cdd:NF033617 481 PMMCSRLLKANEKP---GRFArAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 562 TAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSvNPTTNVGRLVMTLKPRGERRDDVSVVITRLKGRVAA 641
Cdd:NF033617 558 FGMIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGG-NPGDNTGFGIINLKPWDERDVSAQEIIDRLRPKLAK 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 642 IPGMTVYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQL 721
Cdd:NF033617 637 VPGMDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARL 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 722 GVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAASatagapnAQVPLSAVATLTRTTA 801
Cdd:NF033617 717 GISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDG-------KLVPLSTLAKIEERAA 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 802 PLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIeMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLGV 881
Cdd:NF033617 790 PLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAI 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 882 LYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAERGQGMSPNEAIVQACLL 961
Cdd:NF033617 869 QYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRREAIYQAAAL 948
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517268981 962 RFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDR 1022
Cdd:NF033617 949 RLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1027 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1090.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 1 MGVSEPFIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 81 NSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLpYPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADT 160
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDV-EPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 161 LLAQRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADA 240
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 241 YKPVIIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIV 320
Cdd:COG0841 240 FENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 321 SDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVV 400
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 401 DDAIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLT 480
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 481 LTPMMCSRLLKHAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTAS 560
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQ 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 561 ITAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERRDDVSVVITRLKGRVA 640
Cdd:COG0841 560 IIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERDRSADEIIARLREKLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 641 AIPGMTVYFQPVQDvqiSTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQ 720
Cdd:COG0841 640 KIPGARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAA 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 721 LGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAAsatagapNAQVPLSAVATLTRTT 800
Cdd:COG0841 717 LGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPD-------GEMVPLSSVATIEEGT 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 801 APLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLG 880
Cdd:COG0841 790 GPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLA 869
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 881 VLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFAlEAERGQGMSPNEAIVQACL 960
Cdd:COG0841 870 AQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFA-NQLREEGMSLREAILEAAR 948
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517268981 961 LRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRINRRL 1027
Cdd:COG0841 949 LRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
7-1026 |
0e+00 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 1033.53 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTSSF 86
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 87 GVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADTLLAQRL 166
Cdd:PRK10614 87 GSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQTI 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 167 SQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADAYKPVII 246
Cdd:PRK10614 167 SQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAEYQPLII 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 247 AYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIVSDRTVT 326
Cdd:PRK10614 247 HYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIAQDRSPT 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 327 IRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVM 406
Cdd:PRK10614 327 IRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVV 406
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 407 IENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLTLTPMMC 486
Cdd:PRK10614 407 LENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLTLTPMMC 486
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 487 SRLLKhAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTASITAVTE 566
Cdd:PRK10614 487 AWLLK-SSKPREQKRLRGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRLMGFIQ 565
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 567 AGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNPttnvGRLVMTLKPRGERRDDVSVVITRLKGRVAAIPGMT 646
Cdd:PRK10614 566 ADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNS----GMMFITLKPLSERSETAQQVIDRLRVKLAKEPGAN 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 647 VYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQLGVSLQ 726
Cdd:PRK10614 642 LFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDVQ 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 727 GITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAasatAGAPnaqVPLSAVATLTRTTAPLAIS 806
Cdd:PRK10614 722 AANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINN----EGKA---IPLSYFAKWQPANAPLSVN 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 807 HQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLGVLYESY 886
Cdd:PRK10614 795 HQGLSAASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYESY 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 887 IHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAERGQGMSPNEAIVQACLLRFRPI 966
Cdd:PRK10614 875 VHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAIFQACLLRFRPI 954
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 967 MMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRINRR 1026
Cdd:PRK10614 955 MMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLR 1014
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
7-1021 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 906.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTSSF 86
Cdd:pfam00873 5 FIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSSQSSY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 87 GVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLpYPPTYAKVNPADAPVMTLALRSDTISLRAM--SDIADTLLAQ 164
Cdd:pfam00873 85 GLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGV-QRPGISVIKTSLGPIMVLAVTSPDGSYTQTdlRDYADTNIKP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 165 RLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADAYKPV 244
Cdd:pfam00873 164 QLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAEDFEKI 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 245 IIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIVSDRT 324
Cdd:pfam00873 244 IVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVVYDTT 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 325 VTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAI 404
Cdd:pfam00873 324 PFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAI 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 405 VMIENIVRHM-ENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLTLTP 483
Cdd:pfam00873 404 VVVENIERVLeENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVALTLTP 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 484 MMCSRLLKHAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPKGFLPLQDTASITA 563
Cdd:pfam00873 484 ALCATLLKPRREPKHGGFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEGVFVT 563
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 564 VTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAG--SVNPTTNVGRLVMTLKPRGERR---DDVSVVITRLKGR 638
Cdd:pfam00873 564 SAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAfsGDNNGPNSGDAFISLKPWKERPgpeKSVQALIERLRKA 643
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 639 VAAIPGMTVYFQPVQDVQISTQSS--RSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEGGLRAQLTVDRT 716
Cdd:pfam00873 644 LKQIPGANVFLFQPIQLRGLGTISgfRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVNIDRE 723
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 717 RAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPgaaSATAGApnaqVPLSAVATL 796
Cdd:pfam00873 724 KAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVR---NPYGKM----IPLSAFAKI 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 797 TRTTAPLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKALAGQPWLLLAAVITIY 876
Cdd:pfam00873 797 EWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVF 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 877 IVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAERGQGMSPNEAIV 956
Cdd:pfam00873 877 LVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKSLEEAIL 956
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517268981 957 QACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALD 1021
Cdd:pfam00873 957 EACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
8-1001 |
1.45e-155 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 488.00 E-value: 1.45e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 8 IRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTSSFG 87
Cdd:COG3696 10 LRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSISRFG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 88 VSQISLQFDLNRDIDGATQDVQAAINAAAGVLPktlpypptyAKVNPADAP-------VMTLALRSD--TISLRAMSDIA 158
Cdd:COG3696 90 LSVVTVIFEDGTDIYWARQLVLERLQQVREQLP---------AGVTPELGPistglgeIYQYTLESDpgKYSLMELRTLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 159 DTLLAQRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAA 238
Cdd:COG3696 161 DWVIRPQLRSVPGVAEVNSFGGFVKQYQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIERGGQEYLVRGIGLIRSL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 239 DAYKPVIIAYRNGSPVTIADVAQIVDGLENdRTG--GWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVN 316
Cdd:COG3696 241 EDIENIVVKTRNGTPVLLRDVAEVRIGPAP-RRGaaTLNGEGEVVGGIVLMLKGENALEVIEAVKAKLAELKPSLPEGVK 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 317 LTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGT 396
Cdd:COG3696 320 IVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMSLGGLAIDF 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 397 GFVVDDAIVMIENIVRHME------NGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIA 470
Cdd:COG3696 400 GIIVDGAVVMVENILRRLEenraagTPRERLEVVLEAAREVRRPIFFATLIIILVFLPIFTLEGVEGKLFRPMALTVIFA 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 471 VVTSAVVSLTLTPMMCSRLLKHAHEELAVPglaaVSRFIDRtvgFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPK 550
Cdd:COG3696 480 LLGALLLSLTLVPVLASLLLRGKVPEKENP----LVRWLKR---LYRPLLRWALRHPKLVLAVALVLLVLALALFPRLGS 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 551 GFLPLQDTASITAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVnPT----TNVGRLVMTLKPRGERRD 626
Cdd:COG3696 553 EFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRTGRAED-ATdpmgVNMSETFVILKPRSEWRS 631
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 627 DVSV--VITRLKGRVAAIPGMTVYF-QPVQD-VQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEA 702
Cdd:COG3696 632 GRTKeeLIAEMREALEQIPGVNFNFsQPIQMrVDELLSGVRADVAVKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVER 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 703 QEGGLRAQLTVDRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPgaasatag 782
Cdd:COG3696 712 VTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGERRFDIVVRLPEELRDDPEAIRNLPIP-------- 783
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 783 APN-AQVPLSAVATLTRTTAPLAISHQAQFPSISLSFNLApGAALGDAV-EAVKTIETRIEMPNSIVGVYAGDAAEFAKA 860
Cdd:COG3696 784 TPSgAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANVR-GRDLGSFVaEAQAKVAEQVKLPPGYYIEWGGQFENLQRA 862
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 861 LAgqpWLLLAAVITIYIVLGVLY---ESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMI 937
Cdd:COG3696 863 TA---RLAIVVPLALLLIFLLLYlafGSVRDALLILLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLV 939
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517268981 938 DFALEAERgQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGG 1001
Cdd:COG3696 940 SYINQLRA-EGLDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEVQRPLATVVIGG 1002
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
7-1034 |
1.94e-147 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 467.28 E-value: 1.94e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTS-S 85
Cdd:TIGR00915 5 FIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 86 FGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYppTYAKVNPA-DAPVMTLALRSDTISLRA--MSDIADTLL 162
Cdd:TIGR00915 85 DGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQR--QGVRVEKAsSNFLMVIGLVSDDGSMTKedLSDYAASNM 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 163 AQRLSQISGVGRVSVLGGLKpAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSL------DGAQQSYIIAANDQIA 236
Cdd:TIGR00915 163 VDPLSRLEGVGDVQLFGSQY-AMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLgglpavPGQQLNATIIAQTRLQ 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 237 AADAYKPVII-AYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGV 315
Cdd:TIGR00915 242 TPEQFENILLkVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQGM 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 316 NLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIG 395
Cdd:TIGR00915 322 KYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 396 TGFVVDDAIVMIENIVRHM-ENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTS 474
Cdd:TIGR00915 402 IGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 475 AVVSLTLTPMMCSRLLK----HAHEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPK 550
Cdd:TIGR00915 482 VLVALILTPALCATMLKpiekGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPT 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 551 GFLPLQDTASITAVTEAGPDVSFAEMQKRQAEAADAIKADP--DVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERR--- 625
Cdd:TIGR00915 562 SFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEkaNVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTgke 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 626 DDVSVVITRLKGRVAAIP-GMTVYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSEWARKLVAEMRRDPLFRDVSSEAQE 704
Cdd:TIGR00915 642 NSVFAIAGRATGHFMQIKdAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPALTRVRPNGLE 721
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 705 GGLRAQLTVDRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAASatagap 784
Cdd:TIGR00915 722 DEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASG------ 795
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 785 nAQVPLSAVATLTRTTAPLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETriEMPNSIVGVYAGDAAEFAKALAGQ 864
Cdd:TIGR00915 796 -EMVPFSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQ--KLPPGFGFSWTGMSYEERLSGSQA 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 865 PWLLLAAVITIYIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAe 944
Cdd:TIGR00915 873 PALYALSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKEL- 951
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 945 RGQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRIN 1024
Cdd:TIGR00915 952 MAQGKSIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLF 1031
|
1050
....*....|
gi 517268981 1025 RRLEQALPPA 1034
Cdd:TIGR00915 1032 KRKAHEKEMS 1041
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1033 |
2.64e-126 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 409.99 E-value: 2.64e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 1 MGVSEPFIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 81 NSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPyPPTYAKVNPADAPVMTLALRSDTISLRAMSDIADT 160
Cdd:PRK09579 81 TSVSRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAE-DPVLSKEAADASALMYISFYSEEMSNPQITDYLSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 161 LLAQRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQQSYIIAANDQIAAADA 240
Cdd:PRK09579 160 VIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 241 YKPVIIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNLTIV 320
Cdd:PRK09579 240 FAAIPVKTSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 321 SDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVV 400
Cdd:PRK09579 320 YDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 401 DDAIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAVVSLT 480
Cdd:PRK09579 400 DDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 481 LTPMMCSRLLKHAHEElavPGLA-AVSRFIDRTVGFYHRTLLWVLERQRATLVvtFATLIATL--ALYVVAPKGFLPLQD 557
Cdd:PRK09579 480 LSPMMCALLLRHEENP---SGLAhRLDRLFERLKQRYQRALHGTLNTRPVVLV--FAVIVLALipVLLKFTQSELAPEED 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 558 TASITAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNptTNVGRLVmtLKPRGERRDDVSVVITRLKG 637
Cdd:PRK09579 555 QGIIFMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQ--SGIGGFL--LKPWNERERTQMELLPLVQA 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 638 RVAAIPGMTVYFQPVQDVQISTQSSRSQYQYTLTGTDAALVSewarklVAEMrrdplfrdVSSEAQEGGLRAQLTV---- 713
Cdd:PRK09579 631 KLEEIPGLQIFGFNLPSLPGTGEGLPFQFVINTANDYESLLQ------VAQR--------VKQRAQESGKFAFLDIdlaf 696
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 714 ---------DRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAAsatagap 784
Cdd:PRK09579 697 dkpevvvdiDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQ------- 769
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 785 NAQVPLSAVATLTRTTAPLAISHQAQFPSISLSFnlAPGAALGDAVEAVKTIeTRIEMPNSIVGVYAGDAAEFAKAlAGQ 864
Cdd:PRK09579 770 GQLLPLSTLITLSDRARPRQLNQFQQLNSAIISG--FPIVSMGEAIETVQQI-AREEAPEGFAFDYAGASRQYVQE-GSA 845
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 865 PWLLLA-AVITIYIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEA 943
Cdd:PRK09579 846 LWVTFGlALAIIFLVLAAQFESFRDPLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQL 925
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 944 ERGQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRI 1023
Cdd:PRK09579 926 RHEQGLSRREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIYTLLAKP 1005
|
1050
....*....|
gi 517268981 1024 NRRLEQALPP 1033
Cdd:PRK09579 1006 DAAPGVAQAA 1015
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
7-1026 |
2.97e-123 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 402.31 E-value: 2.97e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTSSF 86
Cdd:PRK09577 5 FIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 87 GVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKvNPADAPVMTLALRSDTISLRAMS--DIADTLLAQ 164
Cdd:PRK09577 85 GQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVE-KAADNIQLIVSLTSDDGRLTGVElgEYASANVLQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 165 RLSQISGVGRVSVLGGlKPAVRIQADLARLAAYGIAMEDLRTAIASANVS------GPKGSLDGAQQSYIIAANDQIAAA 238
Cdd:PRK09577 164 ALRRVEGVGKVQFWGA-EYAMRIWPDPVKLAALGLTASDIASAVRAHNARvtigdiGRSAVPDSAPIAATVFADAPLKTP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 239 DAYKPVIIAYR-NGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGVNL 317
Cdd:PRK09577 243 EDFGAIALRARaDGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVKY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 318 TIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTG 397
Cdd:PRK09577 323 QIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIG 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 398 FVVDDAIVMIENIVRHM-ENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTSAV 476
Cdd:PRK09577 403 ILVDDAIVVVENVERLMvEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAF 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 477 VSLTLTPMMCSRLLK----HAHEELAVPGlaAVSRFIDRTVGFYHRTLLWVLERQRATLVVtFATLIATLALYVVA-PKG 551
Cdd:PRK09577 483 LALSLTPALCATLLKpvdgDHHEKRGFFG--WFNRFVARSTQRYATRVGAILKRPLRWLVV-YGALTAAAALLFTRlPTA 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 552 FLPLQDTASITAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGER---RDDV 628
Cdd:PRK09577 560 FLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGFNLYGEGPNGGMIFVTLKDWKERkaaRDHV 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 629 SVVITRLKGRVAAIPGMTVYfqPVQDVQISTQSSRSQYQYTLT---GTDAALVSEWARKLVAEMRRDPLFRDVSSEAQEG 705
Cdd:PRK09577 640 QAIVARINERFAGTPNTTVF--AMNSPALPDLGSTSGFDFRLQdrgGLGYAAFVAAREQLLAEGAKDPALTDLMFAGTQD 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 706 GLRAQLTVDRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAASatagapn 785
Cdd:PRK09577 718 APQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQG------- 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 786 AQVPLSAVATLTRTTAPLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETriEMPNSIVGVYAGDAAEFAKALAGQP 865
Cdd:PRK09577 791 EMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAA--TLPAGIGYAWSGQSFEERLSGAQAP 868
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 866 WLLLAAVITIYIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEAeR 945
Cdd:PRK09577 869 MLFALSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDL-V 947
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 946 GQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTTPVIYLALDRINR 1025
Cdd:PRK09577 948 AQRMSLADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVVVGRLFD 1027
|
.
gi 517268981 1026 R 1026
Cdd:PRK09577 1028 V 1028
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
7-1022 |
5.34e-106 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 355.68 E-value: 5.34e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTSS- 85
Cdd:PRK10555 5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSg 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 86 FGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKvNPADAPVMTLALRSDTISLRAmSDIADTL---L 162
Cdd:PRK10555 85 TGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVR-KTGDTNILTIAFVSTDGSMDK-QDIADYVasnI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 163 AQRLSQISGVGRVSVLGGlKPAVRIQADLARLAAYGIAMEDLRTAIASANVS------GPKGSLDGAQQSYIIAANDQIA 236
Cdd:PRK10555 163 QDPLSRVNGVGDIDAYGS-QYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQiavgqlGGTPSVDKQALNATINAQSLLQ 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 237 AADAYKPVII-AYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGV 315
Cdd:PRK10555 242 TPEQFRDITLrVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 316 NLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIG 395
Cdd:PRK10555 322 EYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 396 TGFVVDDAIVMIENIVRHM-ENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTS 474
Cdd:PRK10555 402 IGLLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 475 AVVSLTLTPMMCSRLLK-----HAHEELAVPGLaaVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAP 549
Cdd:PRK10555 482 VLVAMILTPALCATLLKplkkgEHHGQKGFFGW--FNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 550 KGFLPLQDTASITAVTEAGPDVSFAEMQK--RQAEAADAIKADPDVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERRDD 627
Cdd:PRK10555 560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKvvEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSK 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 628 VSVVItrlkgrvAAIPGMTVYFQPVQDVQISTQS--------SRSQYQYTLT-----GTDAALVsewARKLVAEM-RRDP 693
Cdd:PRK10555 640 TGTSF-------AIIERATKAFNKIKEARVIASSppaisglgSSAGFDMELQdhagaGHDALMA---ARNQLLALaAKNP 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 694 LFRDVSSEAQEGGLRAQLTVDRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYL 773
Cdd:PRK10555 710 ELTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYV 789
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 774 PGAASatagapnAQVPLSAVATLTRTTAPLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETriEMPNSIVGVYAGD 853
Cdd:PRK10555 790 RNKDG-------GMVPFSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVK--QLPNGFGLEWTAM 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 854 AAEFAKALAGQPWLLLAAVITIYIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKKNA 933
Cdd:PRK10555 861 SYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNA 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 934 IMMIDFALEAERgQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLYTT 1013
Cdd:PRK10555 941 ILIVEFANEMNQ-KGHDLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFV 1019
|
....*....
gi 517268981 1014 PVIYLALDR 1022
Cdd:PRK10555 1020 PLFFVLVRR 1028
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
7-1022 |
1.24e-100 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 341.11 E-value: 1.24e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 7 FIRRPIATSLLGIALLIGGLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAMNSTS-S 85
Cdd:PRK15127 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 86 FGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPKTLPYPPTYAKvNPADAPVMTLALRSDTISLRaMSDIADTLLAQ- 164
Cdd:PRK15127 85 TGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVE-KSSSSFLMVVGVINTDGTMT-QEDISDYVAANm 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 165 --RLSQISGVGRVSVLGGlKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGA------QQSYIIAANDQIA 236
Cdd:PRK15127 163 kdPISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTppvkgqQLNASIIAQTRLT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 237 AADAYKPVIIAY-RNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEIPKVQRAIPAGV 315
Cdd:PRK15127 242 STEEFGKILLKVnQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 316 NLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIG 395
Cdd:PRK15127 322 KIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 396 TGFVVDDAIVMIENIVRHM-ENGDSAMEASLKGASEIGFTVISLTVSLIAVFIPLLFMSGLVGRMFREFALTLTIAVVTS 474
Cdd:PRK15127 402 IGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALS 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 475 AVVSLTLTPMMCSRLLKHA----HEELAVPGLAAVSRFIDRTVGFYHRTLLWVLERQRATLVVTFATLIATLALYVVAPK 550
Cdd:PRK15127 482 VLVALILTPALCATMLKPIakgdHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPS 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 551 GFLPLQDTASITAVTEAGPDVSFAEMQKRQAEAAD--AIKADPDVTGVVSVIGAGSVNPTTNVGRLVMTLKPRGERRDD- 627
Cdd:PRK15127 562 SFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDyyLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEe 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 628 --VSVVITRLKGRVAAIP-GMTVYFQPVQDVQISTQssrsqyqytlTGTDAALVSE---------WAR-KLVAEMRRDP- 693
Cdd:PRK15127 642 nkVEAITMRATRAFSQIKdAMVFAFNLPAIVELGTA----------TGFDFELIDQaglghekltQARnQLLGEAAKHPd 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 694 LFRDVSSEAQEGGLRAQLTVDRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEALPMYQRDPSILSKLYL 773
Cdd:PRK15127 712 MLVGVRPNGLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYV 791
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 774 PGAASatagapnAQVPLSAVATLTRTTAPLAISHQAQFPSISLSFNLAPGAALGDAVEAVKTIETRieMPNSIvgVYAGD 853
Cdd:PRK15127 792 RAADG-------QMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASK--LPTGV--GYDWT 860
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 854 AAEFAKALAGQ--PWLLLAAVITIYIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGIILLMGIVKK 931
Cdd:PRK15127 861 GMSYQERLSGNqaPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAK 940
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 932 NAIMMIDFALEAERGQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLLLSQLLTLY 1011
Cdd:PRK15127 941 NAILIVEFAKDLMDKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIF 1020
|
1050
....*....|.
gi 517268981 1012 TTPVIYLALDR 1022
Cdd:PRK15127 1021 FVPVFFVVVRR 1031
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
5-1035 |
5.66e-98 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 333.65 E-value: 5.66e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 5 EPFIRRPIATS---LLGIALLIG-GLLGYFALPVSALPQVDFPTVQVTTQLPGASPDVIASLITAPLERQLGQIPSLSAM 80
Cdd:TIGR00914 3 ERIISFSVAQRwlvLLATLVMAIlGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 81 NSTSSFGVSQISLQFDLNRDIDGATQDVQAAINAAAGVLPktlpypptyAKVNPADAPVMT----------LALRSDTIS 150
Cdd:TIGR00914 83 RSLSRYGLSQVTVIFKDGTDLYFARQLVNERLQQARDNLP---------EGVSPEMGPISTglgeiflytvEAEEGARKK 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 151 LRAMSDIA------DTLLAQRLSQISGVGRVSVLGGLKPAVRIQADLARLAAYGIAMEDLRTAIASANVSGPKGSLDGAQ 224
Cdd:TIGR00914 154 DGGAYTLTdlrtiqDWIIRPQLRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 225 QSYIIAANDQIAAADAYKPVIIAYRNGSPVTIADVAQIVDGLENDRTGGWYQGSPAVIIDIQRQPGANVIDVVSQIRAEI 304
Cdd:TIGR00914 234 EQYLVRAPGQVQSMDDIRNIVIATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 305 PKVQRAIPAGVNLTIVSDRTVTIRASVRDVQFTLILSVVLVTLVVLLFLRSLRATLIAGVALPLSLITSFGIMYFAGFSL 384
Cdd:TIGR00914 314 ETINKTLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISA 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 385 DNLSLMALTIGtgFVVDDAIVMIENIVRHMENGDSAMEASLK----------GASEIGFTVISLTVSLIAVFIPLLFMSG 454
Cdd:TIGR00914 394 NLMSLGALDFG--LIVDGAVVIVENAHRRLAEAQHHHGRQLTlkerlhevfaASREVRRPLIFGQLIITLVFLPIFTLTG 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 455 LVGRMFREFALTLTIAVVTSAVVSLTLTPMMCSRLLKHAHEELAVPGLAAVSRFidrtvgfYHRTLLWVLERQRATLVVT 534
Cdd:TIGR00914 472 VEGKMFHPMAFTVVLALAGAMILSLTFVPAAVALFIRGKVAEKENRLMRVLKRR-------YEPLLERVLAWPAVVLGAA 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 535 FATLIATLALYVVAPKGFLPLQDTASITAVTEAGPDVSFAEMQKRQAEAADAIKADPDVTGVVSVIGAGSVNPTT---NV 611
Cdd:TIGR00914 545 AVSIVLVVWIASRVGGEFIPSLNEGDLAYQALRIPGTSLAQSVAMQQTLEKLIKSFPEVARVFAKTGTAEIATDPmppNA 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 612 GRLVMTLKPRGERRDDVSV---VITRLKGRVAAIPGMTVYF-QPVQdVQISTQSS--RSQYQYTLTGTDAALVSEWARKL 685
Cdd:TIGR00914 625 SDTYIILKPESQWPEGKKTkedLIEEIQEATVRIPGNNYEFtQPIQ-MRFNELISgvRSDVAVKVFGDDLDDLDATAEKI 703
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 686 VAEMRRDPLFRDVSSEAQEGGLRAQLTVDRTRAGQLGVSLQGITDTLNDAFAQRQISTIYGQANQYRVVLEaLPMYQR-D 764
Cdd:TIGR00914 704 SAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIR-LPESLReS 782
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 765 PSILSKLYLPGAASAtaGAPNAQVPLSAVATLTRTTAPLAISHQAQFPSISLSFNlAPGAALGDAV-EAVKTIETRIEMP 843
Cdd:TIGR00914 783 PQALRQLPIPLPLSE--DARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSAN-VRGRDLGSFVdDAKKAIAEQVKLP 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 844 NSIVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLGVLYESYIHPITILSTLPSAGVGAILALMLCGQDLSVIGLIGII 923
Cdd:TIGR00914 860 PGYWITWGGQFEQLQSATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFI 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 924 LLMGIVKKNAIMMIDFaLEAERGQGMSPNEAIVQACLLRFRPIMMTTLAALFGALPLAIESGTGAELRFPLGISIIGGLL 1003
Cdd:TIGR00914 940 ALSGVAVLNGLVMISF-IRKLLEEGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGII 1018
|
1050 1060 1070
....*....|....*....|....*....|..
gi 517268981 1004 LSQLLTLYTTPVIYLALDRINRRLEQALPPAE 1035
Cdd:TIGR00914 1019 TATLLTLFVLPALYRLVHRRRHKGRKEHEPLE 1050
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
354-599 |
2.29e-15 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 81.06 E-value: 2.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 354 RSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMENGDSAMEASLKGASEIGF 433
Cdd:COG1033 240 RSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGLDKREALREALRKLGP 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 434 TVISLTVSLIAVFIPLLFMSglvGRMFREFALTLTIAVVTSAVVSLTLTPMMCSRLLKHAHEELAVPGLAAVSRFIDRTV 513
Cdd:COG1033 320 PVLLTSLTTAIGFLSLLFSD---IPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKKPPELGRLLAKLA 396
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 514 GFYHRtllwvlerqRATLVVTFATLIATLALYVVA-------PKGFLP-----LQDTA----------SITAVTEAGPDV 571
Cdd:COG1033 397 RFVLR---------RPKVILVVALVLAVVSLYGISrlkveydFEDYLPedspiRQDLDfieenfggsdPLEVVVDTGEPD 467
|
250 260 270
....*....|....*....|....*....|
gi 517268981 572 SF--AEMQKRQAEAADAIKADPDVTGVVSV 599
Cdd:COG1033 468 GLkdPEVLKEIDRLQDYLESLPEVGKVLSL 497
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
354-489 |
5.78e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 76.44 E-value: 5.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 354 RSLRATLIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMENGDSAMEASLKGASEIGF 433
Cdd:COG1033 627 RSLRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGK 706
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 517268981 434 TVISLTVSLIAVFIPLLFmSGLvgRMFREFALTLTIAVVTSAVVSLTLTPMMCSRL 489
Cdd:COG1033 707 AILFTSLTLAAGFGVLLF-SSF--PPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
354-648 |
5.33e-07 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 53.62 E-value: 5.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 354 RSLRATLIAGVALPLSLITSFGIMYFAG--FSLDNLSLMALT-IGTGFVVDDAIVMI----ENIVRHmENGDSAMEASLK 426
Cdd:COG2409 191 RSLVAALLPLLTAGLAVGVALGLLALLAafTDVSSFAPNLLTmLGLGVGIDYALFLVsryrEELRAG-EDREEAVARAVA 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 427 GASEI----GFTVIsltVSLIAvfiplLFMSGLvgRMFREFALTLTIAVVTSAVVSLTLTPMMCSrLLKHAHEELAVPGL 502
Cdd:COG2409 270 TAGRAvlfsGLTVA---IALLG-----LLLAGL--PFLRSMGPAAAIGVAVAVLAALTLLPALLA-LLGRRVFWPRRPRR 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 503 AAVSrfiDRTVGFYHRTLLWVLERQRATLVVTFATLIAtLAL------------------------YVVAPKGFlPLQDT 558
Cdd:COG2409 339 RRAA---APESGFWRRLARAVVRRPVPVLVAAVAVLLA-LALpalglrlglpdadslpadspsrqgYDALAEHF-PPGSN 413
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 559 ASITAVTEAGPDVSFAEMQKrQAEAADAIKADPDVTGVVSVIGAGSVNPTTnvgrLVMTLKPRGERRDDVSV-VITRLKG 637
Cdd:COG2409 414 GPLTVVVESDDDLDPADLAA-LDALAAALAAVPGVASVQPPTRPEGTDGDA----ARLQVVPDGDPDSPEAIdLVDRLRD 488
|
330
....*....|..
gi 517268981 638 RVA-AIPGMTVY 648
Cdd:COG2409 489 AAApALEGAEVL 500
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
360-482 |
9.80e-07 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 52.29 E-value: 9.80e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 360 LIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMENGDS---AMEASLKGAseigFTVI 436
Cdd:TIGR01129 274 LIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELRLGKSvrqAIEAGFERA----FSTI 349
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 517268981 437 --SLTVSLIAVFIPLLFMSGLVgrmfREFALTLTIAVVTSAVVSLTLT 482
Cdd:TIGR01129 350 fdANITTLIAALILYVFGTGPV----KGFAVTLAIGIIASLFTALVFT 393
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
360-491 |
2.08e-05 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 48.69 E-value: 2.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 360 LIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMENGDSAMEASLKGASEIGFTVI--S 437
Cdd:PRK13024 292 LIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILdsN 371
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 517268981 438 LTvSLIAVFIPLLFMSGLVgrmfREFALTLTIAVVTSAVVSLTLTPMMCSRLLK 491
Cdd:PRK13024 372 IT-TLIAAAILFFFGTGPV----KGFATTLIIGILASLFTAVFLTRLLLELLVK 420
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
814-976 |
2.44e-05 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 48.32 E-value: 2.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 814 ISLSFNLAPGAALGDAVEAVKTIETRIEMPNS------IVGVYAGDAAEFAKALAGQPWLLLAAVITIYIVLGVLYESYI 887
Cdd:COG1033 164 IVVTLDPDPLSSDLDRKEVVAEIRAIIAKYEDpgvevyLTGFPVLRGDIAEAIQSDLAIFFPLALLLILLLLFLFFRSLR 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 888 HPITILSTLpSAGVGAILALM-LCGQDLSVIGLIGIILLMGIVKKNAIMMIDFALEaERGQGMSPNEAIVQACLLRFRPI 966
Cdd:COG1033 244 GVLLPLLVV-LLAVIWTLGLMgLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYRE-ERRKGLDKREALREALRKLGPPV 321
|
170
....*....|
gi 517268981 967 MMTTLAALFG 976
Cdd:COG1033 322 LLTSLTTAIG 331
|
|
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
360-485 |
1.21e-04 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 45.99 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 360 LIAGVALPLSLITSFGIMYFAGFSLDnLSLMA---LTIGTGfvVDDAIVMIENIVRHMENGdsameASLKGASEIGF--- 433
Cdd:PRK05812 323 LIANIALVANLVLILAVLSLLGATLT-LPGIAgivLTIGMA--VDANVLIFERIREELREG-----RSLRSAIEAGFkra 394
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 517268981 434 --TVI-SLTVSLIAVFIPLLFMSGLVgrmfREFALTLTIAVVTSAVVSLTLTPMM 485
Cdd:PRK05812 395 fsTILdSNITTLIAAIILYALGTGPV----KGFAVTLGIGILTSMFTAITVTRAL 445
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
360-479 |
3.07e-04 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 43.01 E-value: 3.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 360 LIAGVALPLS-LITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENI---VRHMENGD--SAMEASLKGASEIgf 433
Cdd:TIGR00916 73 AIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDRIreeLRKYKGRTfrEAINLGINQTLSR-- 150
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 517268981 434 TVISLTVSLIAVFIPLLFMSGLVgrmfREFALTLTIAVVTSAVVSL 479
Cdd:TIGR00916 151 IIDTNVTTLLAVLALYVFGGGAI----KGFALTLGIGVIAGTYSSI 192
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
800-982 |
1.83e-03 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 42.26 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 800 TAPLAISHQAQFPSISLSFNL-APGAALGDAVEAVKTIETRIEMPNSIVGVYAGDAAEFAKAL-AGQPWLLLAAVITIYI 877
Cdd:TIGR00833 106 AAEGLRSDDGKATIIIVNLAGeKGQKEAQEAINAVRRIVEQTNAPDGLTVHVTGPLATIADILeSGDKDMNRITATTGII 185
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 878 VLGVLYESYIHPITILSTLPSAGVGAILAlmlcgqdLSVIGLIGIILLMGIVKKNAIMM--------IDFAL------EA 943
Cdd:TIGR00833 186 VLIILLLVYRSPITMLVPLVSVGFSVVVA-------QGIVSLLGIPGLIGVNAQTTVLLtalvigagTDYAVfltgryHE 258
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 517268981 944 ERGQGMSPNEAIVQACLLRFRPIMMT--TLAALFGALPLAI 982
Cdd:TIGR00833 259 ERRKGESLEEAAAEALRGTGKAILGSalTVAVAFLALSLAR 299
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
360-493 |
2.47e-03 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 41.91 E-value: 2.47e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 360 LIAGVALPLSLITSFGIMYFAGFSLDNLSLMALTIGTGFVVDDAIVMIENIVRHMENGDSAMEASLKGASEIGFTVISLT 439
Cdd:PRK13023 304 VIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRALSTIVDAN 383
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 517268981 440 VS-LIAVFIPLLFMSGLVgrmfREFALTLTIAVVTSAVVSLTLTPMMCSRLLKHA 493
Cdd:PRK13023 384 LTtLIAALVLFLLGSGTV----HGFALTVAIGIGTTLFTTLTFTRLLIAQWVRTA 434
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
670-976 |
3.04e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 41.52 E-value: 3.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 670 LTGTDAALVSEWARKLVAEMRRDP-LFRDVSSEAQEGGLRaqltvdrtRAGQLGVSLQGITDTLND-AFAQRQIS----- 742
Cdd:TIGR03480 73 IEGPTPEQASRAAERLAEKLAADRtHFEDVYFPGGGPFFR--------RNGLLFLPLEDLEKLTDRlASAQPFLGrlaad 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 743 -TIYGQANQYRVVLEALPMYQRDPSILSKLYLPGAASATAGAPNAQVPLSAVATLTRTTAPLAISHQAQFPSISLSFN-L 820
Cdd:TIGR03480 145 pSLRGLFTALTLALQGLKAGQAQLPGLAPILDALAEALRAFLEGKPAPFSWQALMSGKDAALAPRRRFIIVQPVLDYSsL 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 821 APGAALGDAVEAVKT---IETRIEMPNSIVGVYAGDAAEFAKALAGqpwLLLAAVITIYIVLGVLYESYIHPITILSTLP 897
Cdd:TIGR03480 225 EPAEKAINAIRAAAKdlrLDEDHGVTVRLTGEVALSDEELATVSEG---ATVAGLLSFVLVLVLLWLALRSPRLVFAVLV 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517268981 898 SAGVGAIL----ALMLCGQdLSVIGLIGIILLMGIvkknaimMIDFALE------AERGQGMSPNEAIVQACLLRFRPIM 967
Cdd:TIGR03480 302 TLIVGLILtaafATLAVGH-LNLISVAFAVLFIGL-------GVDFAIQfslryrEERFRGGNHREALSVAARRMGAALL 373
|
....*....
gi 517268981 968 MTTLAALFG 976
Cdd:TIGR03480 374 LAALATAAG 382
|
|
| |
