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Conserved domains on  [gi|517280210|ref|WP_018469028|]
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MULTISPECIES: GntR family transcriptional regulator [Streptomyces]

Protein Classification

GntR family transcriptional regulator( domain architecture ID 11448193)

GntR family transcriptional regulator simlar to MngR, which is involved in the regulation of mannosyl-glycerate transport and metabolism

CATH:  1.10.10.10
Gene Ontology:  GO:0003677|GO:0003700
PubMed:  33509775|26172911|2060763

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
4-116 8.90e-35

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


:

Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 116.43  E-value: 8.90e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210   4 FRIDRRSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAP 83
Cdd:COG1725    1 IRIDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARE 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 517280210  84 AG-GGPGSPLRQGLDAWLAEARAAGLSEPEIRAL 116
Cdd:COG1725   81 LLeERREEFLEEALRELVAEARRLGLSLEELLEL 114
 
Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
4-116 8.90e-35

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 116.43  E-value: 8.90e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210   4 FRIDRRSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAP 83
Cdd:COG1725    1 IRIDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARE 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 517280210  84 AG-GGPGSPLRQGLDAWLAEARAAGLSEPEIRAL 116
Cdd:COG1725   81 LLeERREEFLEEALRELVAEARRLGLSLEELLEL 114
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 15-78 6.15e-15

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 64.39  E-value: 6.15e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517280210  15 YLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVT 78
Cdd:cd07377    3 YEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
C_P_lyase_phnF TIGR02325
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ...
 6-77 1.19e-11

phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]


Pssm-ID: 131378 [Multi-domain]  Cd Length: 238  Bit Score: 59.41  E-value: 1.19e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517280210    6 IDRRSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:TIGR02325   1 IERTSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFV 72
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
18-77 5.41e-11

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 54.12  E-value: 5.41e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210    18 IVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 14-77 8.33e-11

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 53.77  E-value: 8.33e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517280210   14 TYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:pfam00392   1 LYEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
 17-93 1.72e-08

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 51.20  E-value: 1.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210  17 QIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAPA---GGGPGSPLR 93
Cdd:PRK15481   9 EIFDSIRQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIRGSPSPValeGGDPGTPLH 88
 
Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
4-116 8.90e-35

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 116.43  E-value: 8.90e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210   4 FRIDRRSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAP 83
Cdd:COG1725    1 IRIDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARE 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 517280210  84 AG-GGPGSPLRQGLDAWLAEARAAGLSEPEIRAL 116
Cdd:COG1725   81 LLeERREEFLEEALRELVAEARRLGLSLEELLEL 114
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 4-98 6.16e-16

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 72.55  E-value: 6.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210   4 FRIDRRSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAP 83
Cdd:COG1167    3 IRLDRDSSGPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAARLPA 82

                         90
                 ....*....|....*
gi 517280210  84 AGGGPGSPLRQGLDA 98
Cdd:COG1167   83 PAPAPRAAAAVAAPA 97
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 15-78 6.15e-15

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 64.39  E-value: 6.15e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517280210  15 YLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVT 78
Cdd:cd07377    3 YEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
C_P_lyase_phnF TIGR02325
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ...
 6-77 1.19e-11

phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]


Pssm-ID: 131378 [Multi-domain]  Cd Length: 238  Bit Score: 59.41  E-value: 1.19e-11
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517280210    6 IDRRSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:TIGR02325   1 IERTSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFV 72
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
18-77 5.41e-11

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 54.12  E-value: 5.41e-11
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210    18 IVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 14-77 8.33e-11

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 53.77  E-value: 8.33e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517280210   14 TYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:pfam00392   1 LYEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
MngR COG2188
DNA-binding transcriptional regulator, GntR family [Transcription];
9-79 1.29e-10

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441791 [Multi-domain]  Cd Length: 238  Bit Score: 56.79  E-value: 1.29e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517280210   9 RSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTR 79
Cdd:COG2188    1 SSPVPLYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAE 71
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
 17-93 1.72e-08

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 51.20  E-value: 1.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210  17 QIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAPA---GGGPGSPLR 93
Cdd:PRK15481   9 EIFDSIRQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIRGSPSPValeGGDPGTPLH 88
FadR COG2186
DNA-binding transcriptional regulator, FadR family [Transcription];
15-123 1.11e-07

DNA-binding transcriptional regulator, FadR family [Transcription];


Pssm-ID: 441789 [Multi-domain]  Cd Length: 232  Bit Score: 48.39  E-value: 1.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210  15 YLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAPAGGGPGsplrq 94
Cdd:COG2186    9 AEQVAEQLRELILSGELKPGDRLPSERELAEQLGVSRTTVREALRALEALGLVEVRQGGGTFVREPSPWALLDPL----- 83

                         90       100       110
                 ....*....|....*....|....*....|
gi 517280210  95 gldAWLAEARAAGLSE-PEIRALFEQAYAA 123
Cdd:COG2186   84 ---ALLLALDDASLRDlLEARLALEPEAAR 110
PRK10079 PRK10079
phosphonate metabolism transcriptional regulator PhnF; Provisional
 15-77 1.92e-05

phosphonate metabolism transcriptional regulator PhnF; Provisional


Pssm-ID: 182227 [Multi-domain]  Cd Length: 241  Bit Score: 42.45  E-value: 1.92e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517280210  15 YLQIVHQVEQALRmGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:PRK10079  14 YQEIAAKLEQELR-QHYRCGDYLPAEQQLAARYEVNRHTLRRAIDQLVEKGWVQRRQGVGVLV 75
pdhR PRK09464
pyruvate dehydrogenase complex transcriptional repressor PdhR;
18-81 5.09e-05

pyruvate dehydrogenase complex transcriptional repressor PdhR;


Pssm-ID: 181879 [Multi-domain]  Cd Length: 254  Bit Score: 41.16  E-value: 5.09e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517280210  18 IVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSL 81
Cdd:PRK09464  15 IEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSL 78
PRK09764 PRK09764
GntR family transcriptional regulator;
15-77 1.00e-04

GntR family transcriptional regulator;


Pssm-ID: 182065 [Multi-domain]  Cd Length: 240  Bit Score: 40.20  E-value: 1.00e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517280210  15 YLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:PRK09764   7 YRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYV 69
PRK10225 PRK10225
Uxu operon transcriptional regulator;
7-83 2.21e-04

Uxu operon transcriptional regulator;


Pssm-ID: 182318 [Multi-domain]  Cd Length: 257  Bit Score: 39.23  E-value: 2.21e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517280210   7 DRRSGVATYLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVTRSLAP 83
Cdd:PRK10225   3 SATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGS 79
PRK10421 PRK10421
DNA-binding transcriptional repressor LldR; Provisional
 17-77 9.80e-04

DNA-binding transcriptional repressor LldR; Provisional


Pssm-ID: 236690 [Multi-domain]  Cd Length: 253  Bit Score: 37.44  E-value: 9.80e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517280210  17 QIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFV 77
Cdd:PRK10421   6 EVADRVRALIEEKNLEAGMKLPAERQLAMQLGVSRNSLREALAKLVSEGVLLSRRGGGTFI 66
Rrf2 pfam02082
Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur ...
 21-74 1.78e-03

Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 396591 [Multi-domain]  Cd Length: 131  Bit Score: 35.99  E-value: 1.78e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 517280210   21 QVEQALRM---GALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAG 74
Cdd:pfam02082   4 KTDYALHAllyLALHPGGEPVTSEEIAERQNISPVYLEKILAKLRKAGLVESVRGAG 60
PRK11523 PRK11523
transcriptional regulator ExuR;
15-118 3.12e-03

transcriptional regulator ExuR;


Pssm-ID: 183176 [Multi-domain]  Cd Length: 253  Bit Score: 35.98  E-value: 3.12e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517280210  15 YLQIVHQVEQALRMGALREGDQLPTAAQVASSTKVNPNTTLKAYRALESAGLAEVRQGAGTFVT----RSLAPAGG---- 86
Cdd:PRK11523  10 YQQLAAELKERIEQGVYLVGDKLPAERFIADEKNVSRTVVREAIIMLEVEGYVEVRKGSGIHVVsnqpRHQQAADNnmef 89

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 517280210  87 ---GPGSPL--RQGLDAWLAEARAAGLSEPEIRALFE 118
Cdd:PRK11523  90 anyGPFELLqaRQLIESNIAEFAATQVTKQDIMKLMA 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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