|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-471 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 763.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 PVLLERGDTFTITVEEgVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLP 160
Cdd:COG0469 82 PVELKKGDTFTLTTDD-VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 161 GVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDGIMV 240
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 241 ARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPV 320
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 321 TTVRTMAKIVAAAEEVILARGLPPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLAFT 400
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517394152 401 PEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRVHHI 471
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
2-476 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 679.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREGP 81
Cdd:PRK06247 5 RRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 82 VLLERGDTFTITVEEgVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLPG 161
Cdd:PRK06247 85 VQLANGQTFRLDVDD-APGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLPG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 162 VAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRImdeEGRRLPVIAKIEKPQAVEAVDEIVAAFDGIMVA 241
Cdd:PRK06247 164 TVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKI---IGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 242 RGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPVT 321
Cdd:PRK06247 241 RGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 322 TVRTMAKIVAAAEEVILARGLPPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLAFTP 401
Cdd:PRK06247 321 AVRTMARIIRQVERDPTYPPLIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517394152 402 EPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRVHHIGEDDR 476
Cdd:PRK06247 401 NPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYIGEDDV 475
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-468 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 572.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREGP 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 82 VLLERGDTFTITVEEG-VEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLP 160
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIkGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 161 GVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRR-LPVIAKIEKPQAVEAVDEIVAAFDGIM 239
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKdVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 240 VARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHP 319
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 320 VTTVRTMAKIVAAAEEVILARGLPP--LTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVL 397
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNdrKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517394152 398 AFTPEPATRSQLSATWGVETFLGPH-VDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRV 468
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-471 |
7.24e-176 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 502.23 E-value: 7.24e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 -PVLLERGDTFTITVEEG-VEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPR-VRTRVTEGGMVSDHKGL 157
Cdd:cd00288 81 kDISLKAGDKFLVTTDPAaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 158 NLPGVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDG 237
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 238 IMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGK 317
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 318 HPVTTVRTMAKIVAAAEEVILARGL--PPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIP 395
Cdd:cd00288 321 YPVEAVKAMARICLEAEKALSHRVLfnEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 396 VLAFTPEPATRSQLSATWGVETFLGPHV-----DSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVpGSTNLVRVHH 470
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGS-GSTNTMRILT 479
|
.
gi 517394152 471 I 471
Cdd:cd00288 480 V 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-342 |
3.38e-138 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 401.36 E-value: 3.38e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 --PVLLERGDTFTITVEEGV--EGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGP-RVRTRVTEGGMVSDHK 155
Cdd:pfam00224 81 kkDIELKAGDEMIVSTDAKYkgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 156 GLNLPGVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAF 235
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 236 DGIMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSV 315
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|....*..
gi 517394152 316 GKHPVTTVRTMAKIVAAAEEVILARGL 342
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEKALPHRNL 347
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
1-471 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 763.04 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:COG0469 2 MRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKEG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 PVLLERGDTFTITVEEgVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLP 160
Cdd:COG0469 82 PVELKKGDTFTLTTDD-VEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 161 GVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDGIMV 240
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLEEAGGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 241 ARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPV 320
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 321 TTVRTMAKIVAAAEEVILARGLPPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLAFT 400
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517394152 401 PEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRVHHI 471
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
2-476 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 679.73 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREGP 81
Cdd:PRK06247 5 RRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRFADGK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 82 VLLERGDTFTITVEEgVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLPG 161
Cdd:PRK06247 85 VQLANGQTFRLDVDD-APGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVSLPG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 162 VAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRImdeEGRRLPVIAKIEKPQAVEAVDEIVAAFDGIMVA 241
Cdd:PRK06247 164 TVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKI---IGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 242 RGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPVT 321
Cdd:PRK06247 241 RGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 322 TVRTMAKIVAAAEEVILARGLPPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLAFTP 401
Cdd:PRK06247 321 AVRTMARIIRQVERDPTYPPLIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517394152 402 EPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRVHHIGEDDR 476
Cdd:PRK06247 401 NPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYIGEDDV 475
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
2-468 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 572.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREGP 81
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 82 VLLERGDTFTITVEEG-VEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLP 160
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIkGEGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 161 GVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRR-LPVIAKIEKPQAVEAVDEIVAAFDGIM 239
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKGAKdVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 240 VARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHP 319
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 320 VTTVRTMAKIVAAAEEVILARGLPP--LTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVL 397
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNdrKNSDPKPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517394152 398 AFTPEPATRSQLSATWGVETFLGPH-VDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRV 468
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFLVDEePSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
1-461 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 562.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:PRK05826 3 LRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 PVLLERGDTFTITVEEGVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLP 160
Cdd:PRK05826 83 KITLKTGDKFTLDTDQKEEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINIP 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 161 GVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGR-RLPVIAKIEKPQAVEAVDEIVAAFDGIM 239
Cdd:PRK05826 163 GGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLREAGCpHAKIIAKIERAEAVDNIDEIIEASDGIM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 240 VARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHP 319
Cdd:PRK05826 243 VARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKYP 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 320 VTTVRTMAKIVAAAEEvILARGLPPLTEHNKPRTQGGAVARAAAE-IGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLA 398
Cdd:PRK05826 323 VEAVEAMARICKGAEK-EFSINLSKHRLDRQFDRIDEAIAMSAMYaANHLKGVKAIVALTESGRTARLISRFRPGAPIFA 401
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517394152 399 FTPEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPG 461
Cdd:PRK05826 402 VTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
1-473 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 529.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:PRK06354 7 MRRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 PVLLERGDTFTITVEEgVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGP--RVRTRVTEGGMVSDHKGLN 158
Cdd:PRK06354 87 PIELKTGDEFILTSRE-VLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVEEVDKAdgELHCKVLVGGVLSNKKGVN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 159 LPGVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEE-GRRLPVIAKIEKPQAVEAVDEIVAAFDG 237
Cdd:PRK06354 166 FPGVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHnGKHIPIIAKIEKQEAIDNIDAILELCDG 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 238 IMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGK 317
Cdd:PRK06354 246 LMVARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGD 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 318 HPVTTVRTMAKIVAAAEEVILARGLPPLTEHNKpRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVL 397
Cdd:PRK06354 326 YPVEAVQTMATIAVRIEKDLPYRDILSKRPEFT-TTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPIL 404
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517394152 398 AFTPEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRVHHIGE 473
Cdd:PRK06354 405 AVTPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLVGESGSTDLMKVHVVGA 480
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
1-471 |
7.24e-176 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 502.23 E-value: 7.24e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:cd00288 1 LRRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 -PVLLERGDTFTITVEEG-VEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPR-VRTRVTEGGMVSDHKGL 157
Cdd:cd00288 81 kDISLKAGDKFLVTTDPAaKKGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 158 NLPGVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDG 237
Cdd:cd00288 161 NLPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKDIKIIAKIENQEGVNNFDEILEASDG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 238 IMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGK 317
Cdd:cd00288 241 IMVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGK 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 318 HPVTTVRTMAKIVAAAEEVILARGL--PPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIP 395
Cdd:cd00288 321 YPVEAVKAMARICLEAEKALSHRVLfnEMRRLTPRPTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAP 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 396 VLAFTPEPATRSQLSATWGVETFLGPHV-----DSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVpGSTNLVRVHH 470
Cdd:cd00288 401 IIAVTRNEQTARQLHLYRGVYPVLFEEPkpgwqEDTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGS-GSTNTMRILT 479
|
.
gi 517394152 471 I 471
Cdd:cd00288 480 V 480
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
1-469 |
6.02e-154 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 446.04 E-value: 6.02e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:PRK09206 1 MKKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 P-VLLERGDTFTITVEEGVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNL 159
Cdd:PRK09206 81 NdVSLKAGQTFTFTTDKSVVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 160 PGVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEE-GRRLPVIAKIEKPQAVEAVDEIVAAFDGI 238
Cdd:PRK09206 161 PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLKAHgGENIQIISKIENQEGLNNFDEILEASDGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 239 MVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKH 318
Cdd:PRK09206 241 MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 319 PVTTVRTMAKIVAAAEEVILARgLPPLTEHNKPR-TQggAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVL 397
Cdd:PRK09206 321 PLEAVSIMATICERTDRVMNSR-LESNNDNRKLRiTE--AVCRGAVETAEKLDAPLIVVATQGGKSARSVRKYFPDATIL 397
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517394152 398 AFTPEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPpgVP-GSTNLVRVH 469
Cdd:PRK09206 398 ALTTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGAL--VPsGTTNTASVH 468
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
1-342 |
3.38e-138 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 401.36 E-value: 3.38e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:pfam00224 1 LRRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 --PVLLERGDTFTITVEEGV--EGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGP-RVRTRVTEGGMVSDHK 155
Cdd:pfam00224 81 kkDIELKAGDEMIVSTDAKYkgACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDkTLVVEVLNGGVIGSRK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 156 GLNLPGVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAF 235
Cdd:pfam00224 161 GVNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKNIQIIAKIENQEGVNNFDEILEAT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 236 DGIMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSV 315
Cdd:pfam00224 241 DGIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAK 320
|
330 340
....*....|....*....|....*..
gi 517394152 316 GKHPVTTVRTMAKIVAAAEEVILARGL 342
Cdd:pfam00224 321 GNYPVEAVRMMHEICLEAEKALPHRNL 347
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
2-468 |
6.38e-132 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 391.43 E-value: 6.38e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRS-IGLLADLQGPKIRLGRFREG 80
Cdd:PTZ00066 38 KKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARPNAnLGILLDTKGPEIRTGFLKNH 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 -PVLLERGDTFTITVEEGVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNL 159
Cdd:PTZ00066 118 kPITLKEGQTLKITTDYTFLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMNL 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 160 PGVAVSVPALSKKDEDD-LRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDGI 238
Cdd:PTZ00066 198 PGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRHIKIIPKIENIEGLINFDEILAESDGI 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 239 MVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKH 318
Cdd:PTZ00066 278 MVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGKF 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 319 PVTTVRTMAKIVAAAEEVILARGL--PPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPV 396
Cdd:PTZ00066 358 PVEAVNIMAKICFEAETCIDYRVLyhAIHLAVPTPVSVQEAVARSAVETAEDINAKLIIALTETGNTARLISKYRPSCTI 437
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517394152 397 LAFTPEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRV 468
Cdd:PTZ00066 438 LALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNLMKV 509
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
3-450 |
2.16e-125 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 374.70 E-value: 2.16e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 3 RAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG-P 81
Cdd:PLN02461 22 KTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGkP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 82 VLLERGDTFTITVEEGVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEV--TAVDGPRVRTRVTEGGMVSDHKGLNL 159
Cdd:PLN02461 102 VQLKQGQEITITTDYSIKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVlsCDVEAGTVRCRCENSAMLGERKNVNL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 160 PGVAVSVPALSKKDEDD-LRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDGI 238
Cdd:PLN02461 182 PGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAKSILLISKVENQEGLDNFDDILAESDAF 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 239 MVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKH 318
Cdd:PLN02461 262 MVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAY 341
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 319 PVTTVRTMAKIVAAAE----------EVILARGLP--PLTehnkprtqggAVARAAAEIGDFLGARFLVAFTQSGDTARR 386
Cdd:PLN02461 342 PELAVKTMARICREAEasldygalfkEIMRSAPLPmsPLE----------SLASSAVRTANKVKASLIVVLTRGGTTARL 411
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 387 LSRYRSPIPVLA-FTPEPATRS------------QLSATWGVETFLGP------HVDSTDAMVAQVDELLLRHGRCEKGD 447
Cdd:PLN02461 412 VAKYRPAVPILSvVVPEITTDSfdwscsdeaparHSLIYRGLIPVLAEgsakatDSESTEEILEAAIEHAKKKGLCKPGD 491
|
...
gi 517394152 448 VVV 450
Cdd:PLN02461 492 SVV 494
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
7-336 |
3.68e-103 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 312.26 E-value: 3.68e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 7 VCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADetgrSIGLLADLQGPKIRLGRFREGPVLLER 86
Cdd:PRK06739 6 ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDD----SIKILGDVQGPKIRLGEIKGEQITLQA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 87 GDTFTITVEEgVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLPGVAVSV 166
Cdd:PRK06739 82 GDSFILHTQP-VTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVNLPGAIVRL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 167 PALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLP-VIAKIEKPQAVEAVDEIVAAFDGIMVARGDL 245
Cdd:PRK06739 161 PAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKETSPnLIAKIETMEAIENFQDICKEADGIMIARGDL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 246 GVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPVTTVRT 325
Cdd:PRK06739 241 GVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGEHPIESVST 320
|
330
....*....|.
gi 517394152 326 MAKIVAAAEEV 336
Cdd:PRK06739 321 LRLVSEFAEHV 331
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
28-451 |
1.69e-100 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 308.90 E-value: 1.69e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 28 MDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREGPVLLERGDTFTITVEEGVE--GDRHQC 105
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAFAdkGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 106 GTTHAGLAADVTPGERILVDDGKVSLEVTA-VDGPRVRTRVTEGGMVSDHKGLNLPGVAVSVPALSKKDEDDLRWALRTG 184
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGILILHVQShEDEQTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 185 FDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDGIMVARGDLGVEMPLEQVPIVQKRAVEL 264
Cdd:PTZ00300 161 VDMIFASFIRSAEQVGEVRKALGAKGGDIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 265 ARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPVTTVRTMAKIVAAAEEVI------- 337
Cdd:PTZ00300 241 CNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVneyvffn 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 338 LARGLPPLtehnkPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLAFTPEPATRSQLSATWGVET 417
Cdd:PTZ00300 321 SIKKLQPI-----PMSAEEAVCSSAVNSVYETKAKALVVLSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVES 395
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 517394152 418 F------LGpHVDSTDAMVAQVDELLLRHGRCEKGDVVVI 451
Cdd:PTZ00300 396 VffdaerLG-HDEGKEQRVAMGVGFAKSKGYVQSGDLMVV 434
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
2-457 |
5.29e-94 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 296.07 E-value: 5.29e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRK-AADETGRSIGLLADLQGPKIRLGRFREg 80
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEyNAQSKDNVIAIMLDTKGPEVRSGDLPQ- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 PVLLERGDTFTITVEEGVeGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHKGLNLP 160
Cdd:PLN02623 189 PIMLEEGQEFTFTIKRGV-STEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNVR 267
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 161 GVAVSVPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEEGRRLPVIAKIEKPQAVEAVDEIVAAFDGIMV 240
Cdd:PLN02623 268 GKSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNADIHVIVKIESADSIPNLHSIITASDGAMV 347
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 241 ARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPV 320
Cdd:PLN02623 348 ARGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPL 427
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 321 TTVRTMAKIVAAAEEVILARGLPPLTEHNKPRTQGGAVARAAAEIGDFLGARFLVaFTQSGDTARRLSRYRSPIPVLAFT 400
Cdd:PLN02623 428 KAVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMSEMFAFHATMMANTLGTSIIV-FTRTGFMAILLSHYRPSGTIFAFT 506
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 517394152 401 PEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGD-VVVITAGSPP 457
Cdd:PLN02623 507 NEKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEeVALVQSGRQP 564
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
1-457 |
1.85e-91 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 287.41 E-value: 1.85e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 1 MRRAKIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFrEG 80
Cdd:PLN02762 24 TRRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDVIRRVRRLNEEKGFAVAVMMDTEGSEIHMGDL-GG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 P--VLLERGDTFTITVEEgVEGDRHQCgTTHA---GLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVTEGGMVSDHK 155
Cdd:PLN02762 103 AssAKAEDGEEWTFTVRK-FDGSRPEF-TIQVnydGFAEDVKVGDELVVDGGMVRFEVIEKIGPDVKCKCTDPGLLLPRA 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 156 GLNL--PGVAVS-----VPALSKKDEDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDEE--GRRLPVIAKIEKPQAVE 226
Cdd:PLN02762 181 NLTFwrDGSLVRernamLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARsrDSDIGVIAKIESLDSLK 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 227 AVDEIVAAFDGIMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDA 306
Cdd:PLN02762 261 NLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEAVRQRADA 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 307 VMLSGETSVGKHP---VTTVRTMAKIV---AAAEEVILARGLPPLTEHNKPRTqGGAVARAAAEIGDFLGARFLVAFTQS 380
Cdd:PLN02762 341 LMLSGESAMGLYPekaLSVLRSVSLRMelwSREEKRHEALELPQLSSSLSDRI-SEEICNSAAKMANNLGVDAIFVYTKH 419
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517394152 381 GDTARRLSRYRSPIPVLAFTPEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDELLLRHGRCEKGDVVVITAGSPP 457
Cdd:PLN02762 420 GHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDFSDDMESNLNKTFSLLKARGMIKSGDLVIAVSDLTP 496
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
5-399 |
2.91e-80 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 258.45 E-value: 2.91e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 5 KIVCTLGPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREGPVLL 84
Cdd:PLN02765 31 KIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPISL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 85 ERGDTFTITVEEGVEGDRHQCGTTHAGLAADVTPGERILV--------DDGKVSLEVTAVDGPRVRTRVT-----EGGMV 151
Cdd:PLN02765 111 KAGNTVTLTPDQSKEASSEVLPINFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKnsatlAGSLF 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 152 SDHkglnLPGVAVSVPALSKKDEDDLR-WALRTGFDVIALSFVRSGRDILDVHRIMDEEG-RRLPVIAKIEKPQAVEAVD 229
Cdd:PLN02765 191 TLH----VSQVRIDLPTLSEKDKEVIStWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGlSQTQIFAKIENVEGLTHFD 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 230 EIVAAFDGIMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVaTQMLDSMIDNSRPTRAEASDVANAVIDGTDAVML 309
Cdd:PLN02765 267 EILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILL 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 310 SGETSVGKHPVTTVRTMAKIVAAAEEVI-----LARGLPPLTEhnkPRTQGGAVA----RAAAEIgdflGARFLVAFTQS 380
Cdd:PLN02765 346 GAETLRGLYPVETISTVGRICAEAEKVFnqdlyFKKTVKYVGE---PMSHLESIAssavRAAIKV----KASVIIVFTSS 418
|
410
....*....|....*....
gi 517394152 381 GDTARRLSRYRSPIPVLAF 399
Cdd:PLN02765 419 GRAARLIAKYRPTMPVLSV 437
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
265-473 |
4.53e-57 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 191.65 E-value: 4.53e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 265 ARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAVIDGTDAVMLSGETSVGKHPVTTVRTMAKIVAAAEEVILARGLPP 344
Cdd:COG3848 2 CNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQRV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 345 LTEHNKPRTQGGAVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLAFTPEPATRSQLSATWGVETFLGPHVD 424
Cdd:COG3848 82 PRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEESA 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 517394152 425 STDAMVAQVDELLLRHGRCEKGDVVVITAGSPPGVPGSTNLVRVHHIGE 473
Cdd:COG3848 162 STDEMFAVAVALALEAGLVKDGDLVVITAGVPVGVSGTTNLLKVHVVGD 210
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
2-309 |
2.71e-53 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 186.76 E-value: 2.71e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTL-GPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGRFREG 80
Cdd:PRK08187 133 RRTRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVAGP 212
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 81 PV--LLERGDTFTITVE---EGVEGDRHQCGTTHAGLAADVTPGERILVDDGKVSLEVTAVDGPRVRTRVT----EGGMV 151
Cdd:PRK08187 213 LGktRLYTGDRLALVAQgppRRIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGALLEVTharpKGLKL 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 152 SDHKGLNLPGVAVSVPALSKKDEDDLRWALRTGfDVIALSFVRSGRDI------LDVHRIMDEegRRLPVIAKIEKPQAV 225
Cdd:PRK08187 293 KPEKGLNFPDTALDLPALTEKDRADLDFVARHA-DLVGYSFVQSPGDVealqaaLAARRPDDW--RKLGLVLKIETPRAV 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 226 EAVDEIVAAFDG-----IMVARGDLGVEMPLEQVPIVQKRAVELARRNAKPVIVATQMLDSMIDNSRPTRAEASDVANAv 300
Cdd:PRK08187 370 ANLPELIVQAAGrqpfgVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDAAMA- 448
|
....*....
gi 517394152 301 iDGTDAVML 309
Cdd:PRK08187 449 -ARAECVML 456
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
2-329 |
2.53e-42 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 158.57 E-value: 2.53e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 2 RRAKIVCTL-GPATDTYDRIKALVDAGMDVARFNLSHGEHAEHDECYQHVRKAADETGRSIGLLADLQGPKIRLGR---- 76
Cdd:PRK14725 139 RPTRIMVTLpTEAADDPDLVRRLLAAGMDIARINCAHDDPEAWRAMIANVRTAEEELGRRCRIAMDLAGPKLRTGPiapg 218
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 --------------------------------------------------------------------------------
Cdd:PRK14725 219 prviklrptrdalgrvltparlwltasespppspppgpvglpvdpewlarlepgdelrftdargkkrkltvtevddegvl 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 77 -----------------------------FREGPVLLERGDTFTITVEEGV------EGDRHQCGTTHAGLAADVTPGER 121
Cdd:PRK14725 299 aegsqtaylangtllrlgrhdstrvgglpPVEQKLRLKVGDRLVLTRDDAPgdpaqgDAPPARISCTLPEAFRAARVGER 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 122 ILVDDGKVSLEVTAVDGPRVRTRVT----EGGMVSDHKGLNLPGVAVSVPALSKKDEDDLRWALRTGfDVIALSFVRSGR 197
Cdd:PRK14725 379 VWFDDGKIGAVVVKVEADEVELRITharpGGSKLKAGKGINLPDSHLPLPALTDKDLEDLAFVAKHA-DIVALSFVRSPE 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 198 DILDVHRIMDEEG-RRLPVIAKIEKPQAVEAVDEIV------AAFdGIMVARGDLGVEMPLEQVPIVQKRAVELARRNAK 270
Cdd:PRK14725 458 DVRLLLDALEKLGaDDLGVVLKIETRRAFENLPRILleamrhPRF-GVMIARGDLAVEVGFERLAEVQEEILWLCEAAHV 536
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 517394152 271 PVIVATQMLDSMIDNSRPTRAEASDVANAVidGTDAVMLSGetsvGKHPVTTVRTMAKI 329
Cdd:PRK14725 537 PVIWATQVLESLAKKGLPSRAEITDAAMAL--RAECVMLNK----GPHIVEAVRVLDDI 589
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
357-469 |
4.72e-36 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 129.14 E-value: 4.72e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 357 AVARAAAEIGDFLGARFLVAFTQSGDTARRLSRYRSPIPVLAFTPEPATRSQLSATWGVETFLGPHVDSTDAMVAQVDEL 436
Cdd:pfam02887 2 AIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVKV 81
|
90 100 110
....*....|....*....|....*....|...
gi 517394152 437 LLRHGRCEKGDVVVITAGSPPGVPGSTNLVRVH 469
Cdd:pfam02887 82 AKEAGLVKKGDLVVITAGVPFGVSGTTNTLKVI 114
|
|
| CitE |
COG2301 |
Citrate lyase beta subunit [Carbohydrate transport and metabolism]; |
174-256 |
6.73e-05 |
|
Citrate lyase beta subunit [Carbohydrate transport and metabolism];
Pssm-ID: 441876 Cd Length: 288 Bit Score: 44.76 E-value: 6.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517394152 174 EDDLRWALRTGFDVIALSFVRSGRDILDVHRIMDE---EGRRLPVIAKIEKPQAVEAVDEIVAAFDGIMVAR-------G 243
Cdd:COG2301 78 LDDLAALVGAGLDGIVLPKVESAEDVRALAALLTEleaEGGSIPLMALIETARGLLNAAEIAAASPRVEALVfgaedlaA 157
|
90
....*....|...
gi 517394152 244 DLGVEMPLEQVPI 256
Cdd:COG2301 158 DLGARRTRDGDEL 170
|
|
| HpcH |
COG3836 |
2-keto-3-deoxy-L-rhamnonate aldolase RhmA [Carbohydrate transport and metabolism]; |
215-272 |
1.14e-03 |
|
2-keto-3-deoxy-L-rhamnonate aldolase RhmA [Carbohydrate transport and metabolism];
Pssm-ID: 443047 [Multi-domain] Cd Length: 237 Bit Score: 40.48 E-value: 1.14e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517394152 215 VIAKIEKPQAVEAVDEIVA--AFDGIMVARGDLGVEM--PLEQV-PIVQ---KRAVELARRNAKPV 272
Cdd:COG3836 144 VIVQIETAEAVENLDEIAAvpGVDGVFIGPADLSASLghPGQPDhPEVQaaiERVIAAARAAGKPA 209
|
|
| |
