|
Name |
Accession |
Description |
Interval |
E-value |
| pcrA |
TIGR01073 |
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. ... |
5-780 |
0e+00 |
|
ATP-dependent DNA helicase PcrA; Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273429 [Multi-domain] Cd Length: 726 Bit Score: 947.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 5 LTLGLNPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIGPQAERM 84
Cdd:TIGR01073 1 LLAHLNPEQREAVKTTEGPLLIMAGAGSGKTRVLTHRIAHLIAEKNVAPWNILAITFTNKAAREMKERVEKLLGPVAEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 85 WVATFHSVCVRILRQQAQLVpGLNTNFTIYDSDDSRRLLTMIAKDMNLDLKKFSARTLANAISNLKNELIDPDQASASAQ 164
Cdd:TIGR01073 81 WISTFHSMCVRILRRDIDRI-GINRNFSIIDPTDQLSLMKTILKDKNLDPKKFEPRSILGTISNAKNELLPPEDFAKEAT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 165 ttkNPFETTVAEVYVEYQKRLRESNALDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEG 244
Cdd:TIGR01073 160 ---NYFEKVVAEVYQEYQKRLLRNNALDFDDLIMTTINLFQRVPDVLEYYQRKFQYIHVDEYQDTNRAQYTLVRLLASRF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 245 PdapELAVVGDSDQSIYAFRGATIRNIEEFERDYPAAKTILLEQNYRSTQNILEAANAVISQNEGRRPKNLWTDHGSGDK 324
Cdd:TIGR01073 237 R---NLCVVGDADQSIYGWRGADIQNILSFEKDYPNATTILLEQNYRSTKNILQAANEVIEHNSNRKPKNLWTENSSGDK 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 325 IVGYVADNEHDEARFIANEVDSLADQG-VNYSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLR 403
Cdd:TIGR01073 314 ITYYEADTERDEAQFVAGEIDKLVKNGeRKYGDFAILYRTNAQSRVFEETLLKANIPYKIVGGLKFYDRKEIKDILAYLR 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 404 VIDNPDDTVSLRRIVNVPKRAIGDKAQAMVALHADNNDISFGKALIDASEgrVDMLATRAKNAITGFVDMMDTLRAELPS 483
Cdd:TIGR01073 394 VIANPDDDLSLLRIINVPKRGIGASSLEKIVNYALELNISLFEAIGEIDE--IGGLAAKSANALLAFATMIENLRQQQEY 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 484 MTnevtgmpdLGQLVSRILDITGYKAELEASNDPQDGARLDNLNELVSVAREFsseaanqmayqveadadltssvgraei 563
Cdd:TIGR01073 472 LS--------PTELVEEVLDKSGYREMLKAEKTEEAQSRLENLDEFLSVTKEF--------------------------- 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 564 veadDGEPEPGSLQAFLERVSLVADADQIPDNEQG-VVTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRALGDPAELAEER 642
Cdd:TIGR01073 517 ----EDESEDKSLIDFLTDLALVSDLDELEETEEGgAVTLMTLHAAKGLEFPVVFLIGMEEGVFPHSRSLMDEKELEEER 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 643 RLAYVGITRAREKLYLSRAMLRSSWGNSVTNPASRFLAEIPEDLIDWRREEPTYGHSASAWGSGSSSRPSQPSRFGSRAS 722
Cdd:TIGR01073 593 RLAYVGITRAEEELYLTHATMRTLFGRIQMNPPSRFLNEIPAELLETASTGRRTGATDPKGPSIRQAGASRPTTSQPTAG 672
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*...
gi 517408677 723 GrpqkpavkvnKDLDLTTGDKVNHAKYGLGTVTAVDGVGARETVTIDFGSSGTVRLML 780
Cdd:TIGR01073 673 G----------DTLSWAVGDRVNHKKWGIGTVVSVKGGGDDQELDIAFPSIGVKRLLA 720
|
|
| UvrD |
COG0210 |
Superfamily I DNA or RNA helicase [Replication, recombination and repair]; |
3-771 |
0e+00 |
|
Superfamily I DNA or RNA helicase [Replication, recombination and repair];
Pssm-ID: 439980 [Multi-domain] Cd Length: 721 Bit Score: 928.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 3 TDLTLGLNPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIGPQAE 82
Cdd:COG0210 1 SDLLAGLNPEQRAAVEHPEGPLLVLAGAGSGKTRVLTHRIAYLIAEGGVDPEQILAVTFTNKAAREMRERIEALLGRLAR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 83 RMWVATFHSVCVRILRQQAQLVpGLNTNFTIYDSDDSRRLLTMIAKDMNLDLKKFSARTLANAISNLKNELIDPDQASAS 162
Cdd:COG0210 81 GLWVGTFHSLALRILRRHAELL-GLPPNFTILDGDDQLRLIKELLKELGLDEKRFPPRELLSLISRAKNEGLTPEELAEL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 163 AQttKNPFETTVAEVYVEYQKRLRESNALDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVG 242
Cdd:COG0210 160 LA--ADPEWRAAAELYEAYQERLRANNALDFDDLLLLAVRLLEENPEVLEKYQNRFRYILVDEYQDTNPAQYELLRLLAG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 243 EGPDapeLAVVGDSDQSIYAFRGATIRNIEEFERDYPAAKTILLEQNYRSTQNILEAANAVISQNEGRRPKNLWTDHGSG 322
Cdd:COG0210 238 DGRN---LCVVGDDDQSIYGFRGADPENILRFEKDFPDAKVIKLEQNYRSTQNILDAANAVIANNPGRLGKNLWTDNGEG 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 323 DKIVGYVADNEHDEARFIANEVDSLADQGVNYSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYL 402
Cdd:COG0210 315 EKVRLYVAPDEEEEARFVADEIRELHEEGVPLSDIAVLYRTNAQSRALEEALRRAGIPYRVVGGLRFYERAEIKDLLAYL 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 403 RVIDNPDDTVSLRRIVNVPKRAIGDKAQAMVALHADNNDISFGKALIDAseGRVDMLATRAKNAITGFVDMMDTLRAELP 482
Cdd:COG0210 395 RLLANPDDDVALLRILNVPRRGIGAATLERLREAAREEGISLLEALRDL--GELAGLSGRAAKALRRFAELLEALRAAAE 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 483 SMTnevtgmpdLGQLVSRILDITGYKAELEASNDPQDGARLDNLNELVSVAREFsseaanqmayqveadadltssvgrae 562
Cdd:COG0210 473 RLP--------LEELLEALLDESGYEEELREEAGEEAERRLENLEELVDAAARF-------------------------- 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 563 iveadDGEPEPGSLQAFLERVSLVADADQiPDNEQGVVTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRALGDPAELAEER 642
Cdd:COG0210 519 -----EERNPGASLEAFLEELALLSDLDA-ADEDEDAVTLMTLHAAKGLEFPVVFLVGLEEGLFPHQRSLDDEEELEEER 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 643 RLAYVGITRAREKLYLSRAMLRSSWGNSVTNPASRFLAEIPEDLIDWRREEPTYGHSASAWGSGSSSRPSQPSRFGSRAS 722
Cdd:COG0210 593 RLFYVAITRARERLYLTYAASRRLWGETQDNEPSRFLDELPEELLEWVRPKAEAAAAAASAAAALPASGAGAAALAAGAA 672
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 517408677 723 GRPQKPAVKVNKDLDLTTGDKVNHAKYGLGTVTAVDGVGARETVTIDFG 771
Cdd:COG0210 673 AAAAAAGGGAAVAGAGLGRAAAAGGADGGAAGAGGGLAAVALTVLPALL 721
|
|
| uvrD |
PRK11773 |
DNA-dependent helicase II; Provisional |
8-780 |
0e+00 |
|
DNA-dependent helicase II; Provisional
Pssm-ID: 236976 [Multi-domain] Cd Length: 721 Bit Score: 670.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 8 GLNPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIGPQAERMWVA 87
Cdd:PRK11773 9 SLNDKQREAVAAPLGNMLVLAGAGSGKTRVLVHRIAWLMQVENASPYSIMAVTFTNKAAAEMRHRIEQLLGTSQGGMWVG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 88 TFHSVCVRILRQQAQLVpGLNTNFTIYDSDDSRRLLTMIAKDMNLDLKKFSARTLANAISNLKNELIDPDQAsasaQTTK 167
Cdd:PRK11773 89 TFHGLAHRLLRAHWQDA-NLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAQWYINGQKDEGLRPQHI----QSYG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 168 NPFETTVAEVYVEYQKRLRESNALDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEGPda 247
Cdd:PRK11773 164 DPVEQTWLKIYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYQERFTHILVDEFQDTNAIQYAWIRLLAGDTG-- 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 248 pELAVVGDSDQSIYAFRGATIRNIEEFERDYPAAKTILLEQNYRSTQNILEAANAVISQNEGRRPKNLWTDHGSGDKIVG 327
Cdd:PRK11773 242 -KVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTANILKAANALIANNNGRLGKELWTDGGDGEPISL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 328 YVADNEHDEARFIANEVDSLADQGVNYSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLRVIDN 407
Cdd:PRK11773 321 YCAFNELDEARFVVERIKTWQDNGGALSDCAILYRSNAQSRVLEEALLQAGIPYRIYGGMRFFERQEIKDALAYLRLIAN 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 408 PDDTVSLRRIVNVPKRAIGDKAQAMVALHADNNDISFGKALIDASEGRVdmLATRAKNAITGFVDMMDTLRAelpsmtnE 487
Cdd:PRK11773 401 RNDDAAFERVVNTPTRGIGDRTLDVVRQTARDRQLTLWQACRALLQEKV--LAGRAASALQRFIELIDALAQ-------E 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 488 VTGMPdLGQLVSRILDITGYKAELEASNDPQDGARLDNLNELVSVAREFSSEaanqmayqvEADADLTssvgraeivead 567
Cdd:PRK11773 472 TADMP-LHEQTDRVIKDSGLRAMYEQEKGEKGQARIENLEELVTATRQFSYP---------DEDEDLT------------ 529
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 568 dgepepgSLQAFLERVSLVADADQIPDNEQGvVTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRALGDPAELAEERRLAYV 647
Cdd:PRK11773 530 -------PLQAFLSHAALEAGEGQADAHEDA-VQLMTLHSAKGLEFPLVFIVGMEEGLFPSQMSLEEGGRLEEERRLAYV 601
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 648 GITRAREKLYLSRAMLRSSWGNSVTNPASRFLAEIPEDLIDWRREEPTYghsasawgsgsssrpsqpsrfgSRA--SGRP 725
Cdd:PRK11773 602 GITRAMQKLTLTYAESRRLYGKEVYHRPSRFIREIPEECVEEVRLRATV----------------------SRPvsHQRM 659
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*
gi 517408677 726 QKPAVKvNKDLDLTTGDKVNHAKYGLGTVTAVDGVGARETVTIDFGSSGTVRLML 780
Cdd:PRK11773 660 GTPAVE-ANDSGFKLGQRVRHPKFGEGTIVNFEGSGAHARVQVAFQGQGIKWLVA 713
|
|
| uvrD |
TIGR01075 |
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, ... |
8-775 |
0e+00 |
|
DNA helicase II; Designed to identify uvrD members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130147 [Multi-domain] Cd Length: 715 Bit Score: 602.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 8 GLNPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIGPQAERMWVA 87
Cdd:TIGR01075 4 GLNDKQREAVAAPPGNLLVLAGAGSGKTRVLTHRIAWLLSVENASPHSIMAVTFTNKAAAEMRHRIGALLGTSARGMWIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 88 TFHSVCVRILRQQaQLVPGLNTNFTIYDSDDSRRLLTMIAKDMNLDLKKFSARTLANAISNLKNELIDPDQAsasaQTTK 167
Cdd:TIGR01075 84 TFHGLAHRLLRAH-HLDAGLPQDFQILDSDDQLRLLKRLIKALNLDEKQWPPRQAMWYINNQKDEGLRPSHI----QAFD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 168 NPFETTVAEVYVEYQKRLRESNALDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEgpdA 247
Cdd:TIGR01075 159 NPVERTWIKIYQAYQEACDRAGLVDFAELLLRAHELLRNKPHILQHYQERFTHILVDEFQDTNKIQYAWIRLLAGN---T 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 248 PELAVVGDSDQSIYAFRGATIRNIEEFERDYPAAKTILLEQNYRSTQNILEAANAVISQNEGRRPKNLWTDHGSGDKIVG 327
Cdd:TIGR01075 236 GNVMIVGDDDQSIYGWRGAQVENIQKFLKDFPGAETIRLEQNYRSTANILAAANALIANNDERLGKNLWTDGEVGEPISL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 328 YVADNEHDEARFIANEVDSLADQGVNYSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLRVIDN 407
Cdd:TIGR01075 316 YSAFNELDEARFVVSRIKTWQRNGGALDECAVLYRSNAQSRVLEEALLQASIPYRIYGGMRFFERQEIKDALAYLRLIAN 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 408 PDDTVSLRRIVNVPKRAIGDKAQAMVALHADNNDISFGKALIDASEGRvdMLATRAKNAITGFVDMMDTLRaelpsmtNE 487
Cdd:TIGR01075 396 RNDDAAFERVINTPTRGIGDRTLDVVRQAARDRGLTLWQAARELTQEK--VLAGRAASALQRFVELIEALA-------NE 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 488 VTGMPdLGQLVSRILDITGYKA--ELEASNDPQDgaRLDNLNELVSVAREFSSEaanqmayqvEADADLTssvgraeive 565
Cdd:TIGR01075 467 TADMP-LHVQTDHVIKDSGLREmyQQEKGEKGQA--RIENLEELVTATRQFSLP---------ENDEDMT---------- 524
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 566 addgepepgSLQAFLERVSLVADADQIpDNEQGVVTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRALGDPAELAEERRLA 645
Cdd:TIGR01075 525 ---------PLTAFLSHAALEAGEGQA-DAGQDAVQLMTLHSAKGLEFPLVFLVGMEEGMFPSQMSLDEGGRLEEERRLA 594
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 646 YVGITRAREKLYLSRAMLRSSWGNSVTNPASRFLAEIPEDLIDWRREEPTYghsasawgsgsssrpsqpsrfgSRAS--G 723
Cdd:TIGR01075 595 YVGITRAMQKLTITYAETRRLYGKEVYHIPSRFIRELPEECLHEVRLRAQV----------------------SRPTnlG 652
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|..
gi 517408677 724 RPQKPAVKVNKDLDLTTGDKVNHAKYGLGTVTAVDGVGARETVTIDFGSSGT 775
Cdd:TIGR01075 653 RVGTPSVDEINDAGFKLGQRVRHPKFGEGTIINAEGSGEHSRLQIAFQGQGI 704
|
|
| rep |
TIGR01074 |
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. ... |
8-694 |
0e+00 |
|
ATP-dependent DNA helicase Rep; Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130146 [Multi-domain] Cd Length: 664 Bit Score: 567.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 8 GLNPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIG-PQAERMWV 86
Cdd:TIGR01074 1 KLNPQQQEAVEYVTGPCLVLAGAGSGKTRVITNKIAYLIQNCGYKARNIAAVTFTNKAAREMKERVAKTLGkGEARGLTI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 87 ATFHSVCVRILRQQAQLVpGLNTNFTIYDSDDSRRLLTMIAKDMnLDLKKFSARTLANAISNLKNELIDPDQASASAQTT 166
Cdd:TIGR01074 81 STFHTLGLDIIKREYNAL-GYKSNFSLFDETDQLALLKELTEGL-IKDDKDLLDKLISTISNWKNDLLTPEQALASARGE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 167 KnpfETTVAEVYVEYQKRLRESNALDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGegpD 246
Cdd:TIGR01074 159 R---EQTFAHCYALYQAHLRAYNALDFDDLILLPTLLLQQNEEVRNRWQNKIRYLLVDEYQDTNTSQYELVKLLVG---D 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 247 APELAVVGDSDQSIYAFRGATIRNIEEFERDYPAAKTILLEQNYRSTQNILEAANAVISQNEGRRPKNLWTDHGSGDKIV 326
Cdd:TIGR01074 233 RARFTVVGDDDQSIYSWRGARPENLVLLKEDFPQLKVIKLEQNYRSTGRILKAANILIANNPHVFEKKLFSELGYGEKIK 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 327 GYVADNEHDEARFIANEV--DSLADQgVNYSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLRV 404
Cdd:TIGR01074 313 VIECNNEEHEAERIAGEIiaHKLVNK-TQYKDYAILYRGNHQSRLLEKALMQNRIPYKLSGGTSFFSRPEIKDLLSYLRL 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 405 IDNPDDTVSLRRIVNVPKRAIGDKAQAMVALHADNNDISFGKALIDasEGRVDMLATRAKNAITGFVDMMDTLRAElpSM 484
Cdd:TIGR01074 392 LVNPDDDAAFLRIVNTPKREIGPATLEKLGELAMERNKSLFTASFD--MGLLQTLSGRGYESLQRFTDWLVEIRRL--AE 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 485 TNEVtgmpdlGQLVSRILDITGYKAEL-EASNDPQDGA-RLDNLNELVSvarefsseaanQMAYQVEAdadltssvgrae 562
Cdd:TIGR01074 468 RSEP------IEAVRSLIEDIDYENWLyETSPSPKAAEmRMKNVNTLFS-----------WFKEMLEG------------ 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 563 iveadDGEPEPGSLQAFLERVSLVADADQIPDNEQG-VVTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRALgDPAELAEE 641
Cdd:TIGR01074 519 -----DEEDEPMTLTQVVTRLTLRDMLERGEDEEELdQVQLMTLHASKGLEFPYVFIVGMEEGILPHQSSI-EEDNVEEE 592
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|...
gi 517408677 642 RRLAYVGITRAREKLYLSRAMLRSSWGNSVTNPASRFLAEIPEDLIDWRREEP 694
Cdd:TIGR01074 593 RRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLDELPQEDLQWEGDDP 645
|
|
| PRK10919 |
PRK10919 |
ATP-dependent DNA helicase Rep; Provisional |
9-692 |
2.30e-150 |
|
ATP-dependent DNA helicase Rep; Provisional
Pssm-ID: 182838 [Multi-domain] Cd Length: 672 Bit Score: 455.45 E-value: 2.30e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 9 LNPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIGPQAER-MWVA 87
Cdd:PRK10919 3 LNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVAQTLGRKEARgLMIS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 88 TFHSVCVRILRQQAQLVpGLNTNFTIYDSDDSRRLLTMIAKDMnLDLKKFSARTLANAISNLKNELIDPDQASASAQTTK 167
Cdd:PRK10919 83 TFHTLGLDIIKREYAAL-GMKSNFSLFDDTDQLALLKELTEGL-IEDDKVLLQQLISTISNWKNDLKTPAQAAAGAKGER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 168 npfETTVAEVYVEYQKRLRESNALDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEgpdA 247
Cdd:PRK10919 161 ---DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGS---R 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 248 PELAVVGDSDQSIYAFRGATIRNIEEFERDYPAAKTILLEQNYRSTQNILEAANAVISQNEGRRPKNLWTDHGSGDKIVG 327
Cdd:PRK10919 235 ARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGDELKV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 328 YVADNEHDEARFIANEVdsLADQGVN---YSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLRV 404
Cdd:PRK10919 315 LSANNEEHEAERVTGEL--IAHHFVNktqYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 405 IDNPDDTVSLRRIVNVPKRAIGDKAQAMVALHADNNDISFGKALIDAseGRVDMLATRAKNAITGFVDMMDTLrAELpSM 484
Cdd:PRK10919 393 LTNPDDDSAFLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDM--GLSQTLSGRGYESLTRFTHWLAEI-QRL-AE 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 485 TNEVTGMPDLgqlvSRILDitgYKAEL-EASNDPQDGA-RLDNLNELVSVAREF--SSEAANQMAyqveadadLTSSVGR 560
Cdd:PRK10919 469 REPVAAVRDL----IHGID---YESWLyETSPSPKAAEmRMKNVNQLFSWMTEMleGSELDEPMT--------LTQVVTR 533
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 561 AeiveaddgepepgSLQAFLERVSLVADADQipdneqgvVTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRALgDPAELAE 640
Cdd:PRK10919 534 F-------------TLRDMMERGESEEELDQ--------VQLMTLHASKGLEFPYVYLVGMEEGLLPHQSSI-DEDNIDE 591
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|..
gi 517408677 641 ERRLAYVGITRAREKLYLSRAMLRSSWGNSVTNPASRFLAEIPEDLIDWRRE 692
Cdd:PRK10919 592 ERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLIWEQE 643
|
|
| UvrD-helicase |
pfam00580 |
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural ... |
9-279 |
2.11e-117 |
|
UvrD/REP helicase N-terminal domain; The Rep family helicases are composed of four structural domains. The Rep family function as dimers. REP helicases catalyze ATP dependent unwinding of double stranded DNA to single stranded DNA. Swiss:P23478, Swiss:P08394 have large insertions near to the carboxy-terminus relative to other members of the family.
Pssm-ID: 395462 [Multi-domain] Cd Length: 267 Bit Score: 355.40 E-value: 2.11e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 9 LNPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIG-PQAERMWVA 87
Cdd:pfam00580 1 LNPEQRKAVTHLGGPLLVLAGAGSGKTRVLTERIAYLILEGGIDPEEILAVTFTNKAAREMKERILKLLGkAELSELNIS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 88 TFHSVCVRILRQQAQLVpGLNTNFTIYDSDDSRRLLTMIAKD--MNLDLKKFSARTLANAISNLKNELIDPDQAsasAQT 165
Cdd:pfam00580 81 TFHSFCLRILRKYANRI-GLLPNFSILDELDQLALLKELLEKdrLNLDPKLLRKLELKELISKAKNRLLSPEEL---QQG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 166 TKNPFETTVAEVYVEYQKRLRESNALDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEGp 245
Cdd:pfam00580 157 AADPRDKLAAEFYQEYQERLKENNALDFDDLLLLTLELLRSDPELLEAYRERFKYILVDEFQDTNPIQYRLLKLLAGGH- 235
|
250 260 270
....*....|....*....|....*....|....
gi 517408677 246 daPELAVVGDSDQSIYAFRGATIRNIEEFERDYP 279
Cdd:pfam00580 236 --ENLFLVGDPDQSIYGFRGADIENILKFEKDFP 267
|
|
| RecB |
COG1074 |
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, ... |
12-682 |
9.84e-112 |
|
3#-5# helicase subunit RecB of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440692 [Multi-domain] Cd Length: 866 Bit Score: 360.05 E-value: 9.84e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 12 QQTAAVEHSGSpLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIG-------PQAE-- 82
Cdd:COG1074 10 QRRALDPLGGS-VLVEASAGSGKTYTLVARYLRLLLERGLDPEEILVVTFTRAAAAEMRERIRERLAeaadledPDLEel 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 83 ---------------RMWVATFHSVCVRILRQQAQLVpGLNTNFTIYDSDDSR--------------------------- 120
Cdd:COG1074 89 ararrrlaralenldRAAISTIHSFCQRLLREFAFEA-GLDPNFELLDDAEALlleeavddllreayapldalalarlld 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 121 -------RLLTMIAKDMNLDLKKFSARTLAN---AISNLKNELIDPDQASASAQTTKNPFE--------TTVAEVYVEYQ 182
Cdd:COG1074 168 afgrdddSLEELLLALYKLRSRPDWLEELAEldeALEALREALLKAKEALAALREALAAAAapllaallRLLAAVLARYE 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 183 KRLRESNALDFDDLIGEVVRIFKQH--PQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEGPDAPE-LAVVGDSDQS 259
Cdd:COG1074 248 RRKRERGLLDFDDLLHRALRLLRDEdaPWVAERLRERYRHILVDEFQDTSPLQWEILRRLAGEALADGRtLFLVGDPKQS 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 260 IYAFRGATIRNIEEFERDYPA---AKTILLEQNYRSTQNILEAANAVISQ-----------------NEGRRPK-NLWTD 318
Cdd:COG1074 328 IYRFRGADPELFLEARRALEGrvdGERLTLTTNFRSTPEVVDAVNALFAQlmgagfgeipyepvealRPGAYPAvELWPL 407
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 319 HGSGDKIvgyvADNEHDEARFIANEVDSLADQG---------VNYSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRF 389
Cdd:COG1074 408 EPDDVSE----EDAREREARAVAARIRRLLAEGttvegggrpVRPGDIAVLVRTRSEAAAIARALKAAGIPVAASDRLSL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 390 YERKEIRDIIAYLRVIDNPDDTVSLRRIVNVPkrAIGDKAQAMVALHADNNDISFGKALidasegrvdmlatRAKNAITG 469
Cdd:COG1074 484 FESPEVRDLLALLRALLNPEDDLALAAVLRSP--LFGLSDEDLAALAADRKGESLWEAL-------------RAYERLAR 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 470 FVDMMDTLRAELPSMTnevtgmpdLGQLVSRILDITGYKAELEASND-PQDGARLDNLNELVSVAREFSSEaanqmayqv 548
Cdd:COG1074 549 ALERLRALRELARRLG--------LAELLERLLEETGLLERLLALPGgERRLANLLHLDELLQLALEYEQT--------- 611
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 549 eadadltssvgraeiveaddgepEPGSLQAFLERV-SLVADAD----QIPDNEQGVVTLMTLHTAKGLEFPVVFVtgwed 623
Cdd:COG1074 612 -----------------------GGPGLAGFLRWLeRLIEDGGdeekRRLESDADAVRIMTIHKSKGLEFPVVFL----- 663
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 517408677 624 gqfPHLRALGDPAELAEERRLAYVGITRAREKLYLSRAMlrsswGNSVTNPASRFLAEI 682
Cdd:COG1074 664 ---PALRERARAEELAEELRLLYVALTRARDRLVLSGAV-----KKKDAEKESSWLARR 714
|
|
| DEXQc_UvrD |
cd17932 |
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch ... |
10-290 |
3.21e-83 |
|
DEXQD-box helicase domain of UvrD; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. UvrD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350690 [Multi-domain] Cd Length: 189 Bit Score: 263.22 E-value: 3.21e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 10 NPQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKERVSSLIGPQ-AERMWVAT 88
Cdd:cd17932 1 NPEQREAVTHPDGPLLVLAGAGSGKTRVLTHRIAYLILEGGVPPERILAVTFTNKAAKEMRERLRKLLGEQlASGVWIGT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 89 FHSVCVRILRQQAqlvpglntnftiydsddsrrlltmiakdmnldlkkfsartlanaisnlknelidpdqasasaqttkn 168
Cdd:cd17932 81 FHSFALRILRRYG------------------------------------------------------------------- 93
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 169 pfettvaevyveyqkrlresnalDFDDLIGEVVRIFKQHPQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEGPDap 248
Cdd:cd17932 94 -----------------------DFDDLLLYALELLEENPDVREKLQSRFRYILVDEYQDTNPLQYELLKLLAGDGKN-- 148
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 517408677 249 eLAVVGDSDQSIYAFRGATIRNIEEFERDYPAAKTILLEQNY 290
Cdd:cd17932 149 -LFVVGDDDQSIYGFRGADPENILDFEKDFPDAKVIKLEENY 189
|
|
| UvrD_C |
pfam13361 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
284-659 |
1.52e-78 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 433145 [Multi-domain] Cd Length: 377 Bit Score: 257.72 E-value: 1.52e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 284 ILLEQNYRSTQNILEAANAVISQNEGRRP----KNLWTDHGSGDKIVGYVADNEHDEARFIANEVDSLADQGVNYSDIAV 359
Cdd:pfam13361 1 IHLEINYRSTKNLLKAANEFINNNFGRATiypkKILAETVEDGEKIKIIEAETEEEEAEWIALEIKKLVARDEKYNDIAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 360 MYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLRVIDNPDDTVSLRRIVNVPKRAIGDKAQAMVALHADN 439
Cdd:pfam13361 81 LTRSNSDADLIEEALKKLGIPYFVVGQTKFFRREEIKDILAYLRLIANKHDSISLKRILNGPKRGIGNATLERIREYKKR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 440 NDISFGKALIDASEGRVDMLATRAKNAI-------TGFvdmmDTLRAELPSMT-NEVTGMPDLGQLVSRILDITGYKAEL 511
Cdd:pfam13361 161 GLRLSDFINPDTLTYGDPFVIALEQDNIvvfdvetTGL----DTTEDEIIQIAaIKLNKKGVVIESFERFLRLKKPVGDS 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 512 EASNDPQDGARLDNLNELVSVAREFSSeaanqmayQVEADADLTSSvgraeIVEADDGEPEPG---SLQAFLERVSLVAD 588
Cdd:pfam13361 237 LQVHGFSDEFLQENGETPAEALRDFLE--------KLENLRELYSI-----LREYDDIEETPEpedALRNFLEIATLSNS 303
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517408677 589 ADQ-IPDNEQgvVTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRALGDPAELAEERRLAYVGITRAREKLYLS 659
Cdd:pfam13361 304 ELEgSDIKER--IPIMTIHQAKGLEFDTVFLAGLEEGIFPSYRSIKDEGNLEEERRLFYVAITRAKKRLYIS 373
|
|
| addA_Gpos |
TIGR02785 |
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, ... |
11-658 |
1.01e-44 |
|
helicase-exonuclease AddAB, AddA subunit, Firmicutes type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274299 [Multi-domain] Cd Length: 1230 Bit Score: 174.12 E-value: 1.01e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 11 PQQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTqRGVAPWQILAITFTNKAAAEMKERVSSLIG------------ 78
Cdd:TIGR02785 4 DEQWQAIYTRGQDILVSASAGSGKTAVLVERIIRKIT-RGVDVDRLLVVTFTNAAAREMKERIAEALEkelvqepnskhl 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 79 -------PQAErmwVATFHSVCVRILRQQAQLVpGLNTNFTIYD------------------------------------ 115
Cdd:TIGR02785 83 rrqlallNTAN---ISTLHSFCLKVIRKHYYLL-DLDPSFRILTdteqlllikevlddvfeeeyykedkeaffelvdnfs 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 116 ---SDDSRR--------------------------------------LLTMIAKDMNLDLKKFSARTLANAISNLK---- 150
Cdd:TIGR02785 159 gdrSDDGLRdlilqlydfsrstpnpekwlnnlaeayevkekftieslKLQQQIKELLKNELEGLQEKLQRALELFMaedg 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 151 ---------------NELIDPDQASAS-------------------------------AQTTKNPFETTVAEV------- 177
Cdd:TIGR02785 239 laprlenfqldlqniDELIQESLAQADwnelrkavaafkfknlkaakgdeedadlleeADKLREEAKKQLEKLktdyftr 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 178 -------------------------YVE-YQKRLRESNALDFDDLIGEVVRIFKQHP----QVTDYYRRRFRHVLVDEYQ 227
Cdd:TIGR02785 319 seedhlrimqemkpvvktlvqlvkdFIErFGAEKREKNILDFSDLEHYALQILTNENespsEAAEFYREKFHEVLVDEYQ 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 228 DTNHAQyELVHTLVGEGPDAP-ELAVVGDSDQSIYAFRGAT----IRNIEEFERDYP-AAKTILLEQNYRSTQNILEAAN 301
Cdd:TIGR02785 399 DTNLVQ-ESILQLVKRGPEEEgNLFMVGDVKQSIYRFRQADpllfLEKYHRFAQEGEeHGKRIDLAENFRSRAEVLDTTN 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 302 AVISQNEGRR----------------------PKNLWTDHGSGDKIVGYVADNEHD-----------EARFIANEVDSLA 348
Cdd:TIGR02785 478 FLFKQLMDEEvgeidydeeaqlkfgaakypenPDNKTEELLYEKLLIEEAEEEEIDeeaeildkaqqEATMVAERIKALI 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 349 DQG-------------VNYSDIAVMYRTNNASRAVEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLRVIDNPDDTVSLr 415
Cdd:TIGR02785 558 KEGfkvydkktgtyrpVTYRDIVILTRSRGWNLQIMEEFKKYGIPVFANDAENYFQTTEVRVMLSLLRVIDNPYQDIPL- 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 416 riVNVPKRAI-GDKAQAMVALHADNNDISFGKALID--ASEGRVDMLATRAKNaitgFVDMMDTLRAElpSMTNEVTgmp 492
Cdd:TIGR02785 637 --VAVLRSPIvGFDENELALIRLENKDSSYYEAVKDyvKAGLIEDELYEKLNT----FLDSLQKWREF--ARTHSVS--- 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 493 dlgQLVSRILDITGYKAELEASndPQDGARLDNLNELVSVAREFSSEA----------ANQMayqVEADADLTSSVGRAE 562
Cdd:TIGR02785 706 ---ELIWKIYNDTGYYDYVGGL--PGGKQRQANLYALYERARQYESTSfkglfqfirfIERM---QERQKDLASAVAVGE 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 563 iveaddgepepgslqaflervslvadadqiPDNeqgVVTLMTLHTAKGLEFPVVFVTGWeDGQF-------PHL--RALG 633
Cdd:TIGR02785 778 ------------------------------AEN---AVRLMTIHKSKGLEFPVVFVLGM-GKQFnkqdlnsSYLldRQLG 823
|
890 900 910 920 930
....*....|....*....|....*....|....*....|....*....|.
gi 517408677 634 ------DPAE--------------------LAEERRLAYVGITRAREKLYL 658
Cdd:TIGR02785 824 lgikyiDPQErlsypslpkvaikqkmkrelLSEEMRVLYVALTRAKEKLIL 874
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
9-337 |
1.38e-31 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 131.61 E-value: 1.38e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 9 LNPQQTAAV---EHSgspLLIVAGAGSGKTAVLTRRIAYLLtQRGVA-PWQILAITFTNKAAAEMKERVSSLIGpqAERM 84
Cdd:PRK11054 197 LNPSQARAVvngEDS---LLVLAGAGSGKTSVLVARAGWLL-ARGQAqPEQILLLAFGRQAAEEMDERIRERLG--TEDI 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 85 WVATFHSVCVRILRQQAQLVPglntNFTIYDSDDSRRLLTMI-------------AK----------DMNLDLKKFS--- 138
Cdd:PRK11054 271 TARTFHALALHIIQQGSKKVP----VISKLENDSKARHALLIaewrkqcsekkaqAKgwrqwlteelQWDVPEGNFWdde 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 139 --ARTLANAISNL----------KNELIdpDQASASAQTTKNPFETTVAEVYVEYQKRLRESNALDFDDLIgevvrifkq 206
Cdd:PRK11054 347 klQRRLASRLERWvslmrmhggsQAEMI--AQAPEEVRDLFQKRLKLMAPLLKAWKKALKAENAVDFSGLI--------- 415
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 207 HpQVTDYYRR-RF----RHVLVDEYQDTNHAQYELVHTLVGEGPDApELAVVGDSDQSIYAFRGATIRNIEEFERDYPAA 281
Cdd:PRK11054 416 H-QAVNYLEKgRFispwKHILVDEFQDISPQRAALLAALRKQNSQT-TLFAVGDDWQAIYRFSGADLSLTTAFHERFGEG 493
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 517408677 282 KTILLEQNYRSTQNILEAANAVISQNEGRRPKNLwTDHGSGDKIVGYVADNEHDEA 337
Cdd:PRK11054 494 DRCHLDTTYRFNSRIGEVANRFIQQNPHQLKKPL-NSLTKGDKKAVTLLPEDQLEA 548
|
|
| AddB |
COG3857 |
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair]; |
25-692 |
1.28e-29 |
|
ATP-dependent helicase/DNAse subunit B [Replication, recombination and repair];
Pssm-ID: 443066 [Multi-domain] Cd Length: 1019 Bit Score: 126.40 E-value: 1.28e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 25 LIVAGAGSGKTAVLTRRIAYLLTQRgvAPWQIL---AITF-TNKAAAEMkERVSSLIGPQaermwVATFHSVCVRILRQQ 100
Cdd:COG3857 2 FILGRAGSGKTTYLLEEIKEELKEG--KPIILLvpeQMTFqAERALLKR-LGLGGSIRAQ-----VLSFSRLAWRVLQET 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 101 aqlvpGLNTNFTIyDSDDSRRLLTMIAKDMNLDLKKFS--------ARTLANAISNLKNELIDPDQASASAQTTKNPFET 172
Cdd:COG3857 74 -----GGATRPLL-SDAGKRMLLRKILEEHKDELKVFAraadkpgfIEQLAELITELKRYGITPEDLEEAAELLKEKLRD 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 173 tVAEVYVEYQKRLRESNaLDFDDLIGEVVRIFKQHPQVTDyyrrrfRHVLVDEYQDTNHAQYELVHTLVGEGPDAPELAV 252
Cdd:COG3857 148 -LALIYEAYEEKLAGRY-IDSEDLLRLLAEKLEKSEFLEG------AEIYIDGFTDFTPQELELLEALLKKAKEVTITLT 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 253 VGDSDQSIYAFRGATIRNIEEFerdypaAKTILLEQNYRSTQNIleaanAVISQNEGRRPKNlwtdhGSGDKIVGYVADN 332
Cdd:COG3857 220 LDPDELDLFSATGETYERLLEL------AKENGVEVEFKKSPEL-----AHLERNLFAYPPE-----EEPEGIEIIEAAN 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 333 EHDEARFIANEVDSLA-DQGVNYSDIAVMYRTNNASRA-VEDIFIRSGIPYKVVGGTRFYERKEIRDIIAYLRVIDNPDD 410
Cdd:COG3857 284 RRAEVEAVAREIRRLVrEEGYRYRDIAVVVRDLEAYAPlIERVFAEYGIPYFIDEKRPLSHHPLVELILSLLELVRSNFR 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 411 TVSLRRIVnvpK----RAIGDKAQAMVALHADNNDISfGKALIDASEGRVDMLATRAKNAITGFVDMMDTLRAELPSMTN 486
Cdd:COG3857 364 YEDVFRLL---KtgllRPLSREEIDRLENYVLAYGIR-GRRWLERYLEEEEELTDEEEEDLERLNELRDRLLEPLLPLRE 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 487 EVTGMPDLGQLVSRILDItgykaeLEASNDPqdgarlDNLNELVSVAREFSSEAANQMAYQVEAdadLTSSVGraEIVEA 566
Cdd:COG3857 440 RLKKAKTVREWAEALYEF------LEELGVP------EKLEEWREAEEAGDLEEAREHEQAWNA---LIELLD--ELVEV 502
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 567 ddGEPEPGSLQAFLERVSLVADA---DQIPDNEqGVVTLMTLHTAKGLEFPVVFVTGWEDGQFP---------------H 628
Cdd:COG3857 503 --LGDEKLSLEEFLRILESGLEEltfGLIPPSL-DQVQVGGLDRARGLDFKAVFVLGLNEGVFParpredgllsdeereR 579
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 629 LRALG------DPAELAEERRLAYVGITRAREKLYLSRAMLRSswGNSVTNPaSRFLAEIPEDLIDWRRE 692
Cdd:COG3857 580 LNELGlelpptSRERLLEERFLFYRALTRASERLYLSYPLADE--EGKALLP-SPLIDRLRELFPELEER 646
|
|
| PRK13909 |
PRK13909 |
RecB-like helicase; |
28-402 |
1.97e-29 |
|
RecB-like helicase;
Pssm-ID: 237554 [Multi-domain] Cd Length: 910 Bit Score: 125.47 E-value: 1.97e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 28 AGAGSGKTAVLTRR-IAYLLtqRGVAPWQILAITFTNKAAAEMKERV---------------------------SSLIGP 79
Cdd:PRK13909 5 ASAGSGKTFALSVRfLALLF--KGANPSEILALTFTKKAANEMKERIidtllnlekekeeselneleeklglskEELLNK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 80 QAERMW--------VATFHSVCVRILRQQAQLVpGLNTNFTIYDS---------------DDSRRLLT--MIAKDM---- 130
Cdd:PRK13909 83 RDKVYQeflnselkISTIDAFFQKILRKFCLNL-GLSPDFSIKEDtkeelnekflsalskEELLELLAfiKQCESKknns 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 131 -----------NLDLKKFSARTLANA---------ISNLKNELIDPDQASASAQTT--KNPFE----------------- 171
Cdd:PRK13909 162 ffelleklyekNNELKLFEKAKNPIEfdeekfleeLRSLKQQIQSIETASKNAKKAfkKEDFEellnssktwlekeseyr 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 172 -------TTVAEVYVEYQKRLRE------------------------------SNALDFDDLIGEVVRIFKQHPQVTD-- 212
Cdd:PRK13909 242 yfkklynEELDAEFEELKNALKRyydakenyklsklfkllqlykeaknelnkkKNALDFDDISKKVYELLGEEEIDKDfl 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 213 YYR--RRFRHVLVDEYQDTNHAQYELVHTLV-----GEG-PDAPELAVVGDSDQSIYAFRGATIRNIEEFERDYPaAKTI 284
Cdd:PRK13909 322 YFRldSKISHILIDEFQDTSVLQYKILLPLIdeiksGEGqKKFRSFFYVGDVKQSIYRFRGGKKELFDKVSKDFK-QKVD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 285 LLEQNYRSTQNILEAANAVISQNEgrrpKNLWTDHGSGDKIVGYVA---DNEHDEARF--IANEVDSLADQGVNYSDIAV 359
Cdd:PRK13909 401 NLDTNYRSAPLIVDFVNEVFKKKY----KNYKTQYAEQHKSGGYVEvveVADESEELLeqLLQEIQFLLEKGIDPDDIAI 476
|
490 500 510 520
....*....|....*....|....*....|....*....|....*
gi 517408677 360 MYRTNNASRAVEDiFIRSGIPYKVVGGT--RFYERKEIRDIIAYL 402
Cdd:PRK13909 477 LCWTNDDALEIKE-FLQEQFGIKAVTESsaKLINQPEVKALIEAL 520
|
|
| addA_alphas |
TIGR02784 |
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, ... |
139-656 |
9.26e-29 |
|
double-strand break repair helicase AddA, alphaproteobacterial type; AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274298 [Multi-domain] Cd Length: 1135 Bit Score: 123.64 E-value: 9.26e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 139 ARTLANAISNLKnELIDPDQASASAQTTKNPFetTVAEVYVE-YQKRLRESNALDFDDLIGEVVRIFKQhPQVTDY--YR 215
Cdd:TIGR02784 311 AEALEDAASRVE-ALRERLRALRMAQRTLAAL--RLAARLLQrYARLKKARGLLDFNDLIERTVALLAR-PGAGAWvhYK 386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 216 --RRFRHVLVDEYQDTNHAQYELVHTL-----VGEGPDAP---ELAVVGDSDQSIYAFRGATIRNIEEfERDYPAAKT-- 283
Cdd:TIGR02784 387 ldRGIDHILVDEAQDTSPEQWDIIQALaeeffSGEGARSGverTIFAVGDEKQSIYSFQGADPERFAE-ERREFSRKVra 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 284 -------ILLEQNYRSTQNILEAANAVISQ---NEGRRPKNLWTDHGS-GDKIVGYV----------ADNEHDE------ 336
Cdd:TIGR02784 466 vgrkfedLSLNYSFRSTPDVLAAVDLVFADpenARGLSADSDAPVHEAfRDDLPGRVdlwdliskeeGEEPEDWtdpvde 545
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 337 ----------ARFIANEVDSLADQG---------VNYSDIAVMYRtnNASRAVEDIfIRS----GIPykVVGGTRFYERK 393
Cdd:TIGR02784 546 lgerapevrlAERIAAEIRAWLDRGtpipgrgraVRPGDILVLVR--KRDAFFSAL-IRAlkrrGIP--VAGADRLKLTS 620
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 394 EI--RDIIAYLRVIDNPDDTVSLRRIVNVPkraigdkaqamvalhadnndisfgkaLIDASEGRVDMLA-TRAKNAI--- 467
Cdd:TIGR02784 621 HIavKDLMALGRFVLQPEDDLSLAALLKSP--------------------------LFGLDEDDLFRLAaGRSGGSLwaa 674
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 468 -----TGFVDMMDTLRAELpSMTNEVTGMpdlgQLVSRILDITGYKAELEasndpqdgARL-----DNLNELVSVArefs 537
Cdd:TIGR02784 675 lrrreAEFAATLAVLRDWL-SLADFLTPF----EFYARLLGRDGGRRKLL--------ARLgaeaeDILDEFLSQA---- 737
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 538 seaanqMAYQVEadadltssvgraeiveaddgepEPGSLQAFLErvSLVADADQI---PDNEQGVVTLMTLHTAKGLEFP 614
Cdd:TIGR02784 738 ------LAYERT----------------------GLPGLQAFLS--WLEADDPEIkreMDQARDEVRVMTVHGAKGLEAP 787
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517408677 615 VVFV--TG---WEDGQFPHLRALG---------------DPAELA------------EERRLAYVGITRAREKL 656
Cdd:TIGR02784 788 VVFLvdTGskpFASQRAPLLLATGgsggkaplwrpasafDPSLSAaarerlkeraedEYRRLLYVAMTRAEDRL 861
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
600-659 |
1.66e-26 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 105.78 E-value: 1.66e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517408677 600 VTLMTLHTAKGLEFPVVFVTGWEDGQFPHLRA----LGDPAELAEERRLAYVGITRAREKLYLS 659
Cdd:cd18807 86 VTLMTIHASKGLEFPVVFIVGLGEGFIPSDASyhaaKEDEERLEEERRLLYVALTRAKKELYLV 149
|
|
| SF1_C_UvrD |
cd18807 |
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase ... |
292-375 |
1.78e-22 |
|
C-terminal helicase domain of UvrD family helicases; UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350194 [Multi-domain] Cd Length: 150 Bit Score: 94.22 E-value: 1.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 292 STQNILEAANAVISQNEGRRPKNLWTDHGSGDKIVGYVADNEHDEARFIANEVDSLADQG-VNYSDIAVMYRTNNASRAV 370
Cdd:cd18807 1 STKNILDAANSLIKQNKNRPKKPLKAGNKSGGPVELLLAKDEADEAKAIADEIKRLIESGpVQYSDIAILVRTNRQARVI 80
|
....*
gi 517408677 371 EDIFI 375
Cdd:cd18807 81 EEALR 85
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
12-387 |
9.97e-14 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 74.87 E-value: 9.97e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 12 QQTAAVEHSGSPLLIVAGAGSGKTAVLTRRIAYLLTQRgvAPWQILaITFTNKA-AAEMKERVSS-----LIGPQAERMW 85
Cdd:COG3972 164 QERIARSIPDGPQRIRGVAGSGKTVLLAAKAAYLALKH--PGWRIL-VTCFNRSlADHLRDLIPRflrrfSNGEPEDNVK 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 86 VATFHSVCVRILRQQaqlvpglntnftiydsddsrrlltmiakdmNLDLKKFSArtlanaisnlknelidpdqasasaqt 165
Cdd:COG3972 241 LIVFHAWGGKLLKQY------------------------------GIPPLTFSQ-------------------------- 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 166 TKNPFETTVAEVyveyqkrLRESNALDFddligevvrifkqhpqvtdyyRRRFRHVLVDEYQDTNHAQYELV-HTLVgeg 244
Cdd:COG3972 265 PNEAFDEACKAL-------LEAIQGEII---------------------PPIYDAILIDEAQDFEPEFLRLLyQLLK--- 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 245 PDAPELAVVGDSDQSIYAFRGATIRNIEEFERdypaaKTILLEQNYRSTQNILEAANAVISQNEgRRPKNLWTDHG---- 320
Cdd:COG3972 314 PPKKRLIWAYDEAQNIYGRKIPSAGGIPAGIG-----RDTILKKNYRNTRPILTFAHAFGMGLL-RPPGLLQGDAEdyev 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 321 --SGDKIV-----------GYVA-----DNEHDEARFIANEV-DSLADQGVNYSDIAVMYRTNNASR----AVEDIFIRS 377
Cdd:COG3972 388 erPGDKVTlirppepagrkGPLPefkkyDDRAEELEAIAEEIkKNLRDEGLRPSDIAVIYLGNNEAKelgdRLAAALERQ 467
|
410
....*....|
gi 517408677 378 GIPYKVVGGT 387
Cdd:COG3972 468 GIDSYIAGAR 477
|
|
| HelD |
COG3973 |
DNA helicase IV [Replication, recombination and repair]; |
24-386 |
2.08e-13 |
|
DNA helicase IV [Replication, recombination and repair];
Pssm-ID: 443173 [Multi-domain] Cd Length: 699 Bit Score: 73.75 E-value: 2.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 24 LLIVAG-AGSGKTAVLTRRIAYLL-TQRG---------VAP-----------------WQILAITFtnkaaAEMKERVSS 75
Cdd:COG3973 207 VLVVQGgAGSGKTAVALHRAAYLLyTHRErlerggvliVGPnrlfldyisqvlpslgeEGVVQTTF-----GDLVPELLG 281
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 76 LIGPQAERMWVATF--HSVCVRIL----RQQAQLVPG----LNTNFTIYDSDDSRRLLT--MIAKDMNLDLKKFSAR--- 140
Cdd:COG3973 282 VEATAEEDPEVARLkgSLRMAEVLdravRDLEREVPFedirVEGGEVILSAEEIAEAFYraRRSLPHNKRRERLRERlld 361
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 141 TLANAISNLKNELIDPDQASASAQTTKNPF----------ETTVAEVY------VEYQKRLRESN-ALDFDDLIGEVVRI 203
Cdd:COG3973 362 ALKDQLAAELGKLWDEERDELRRELRRSKPvraalnrlwpFLDPAELYrdlfsdPELLARAAGWLsPEERALLLRPTREL 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 204 FKQHPQVTDYY--------------RRRFRHVLVDEYQDTNHAQYELVHTLvgeGPDAPeLAVVGDSDQSIYAFRGATIR 269
Cdd:COG3973 442 KKGRWTVADVAlldelaellggpdrTWTYGHVVVDEAQDLSPMQWRVLKRR---FPSAS-FTIVGDLAQAIHPYRGAESW 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 270 N--IEEFERDYpaAKTILLEQNYRSTQNILEAANAVISQNEG--------RRpknlwtdhgSGDKIVGYVADNEHDEARF 339
Cdd:COG3973 518 EevLEPLGGDR--ARLVELTKSYRSTAEIMEFANRVLRAAGPdlpppesvRR---------HGEPPRVVRVPSEAELAAA 586
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 517408677 340 IANEVDSLADQGvnYSDIAVMYRTNNASRAVEDiFIRSGIPYKVVGG 386
Cdd:COG3973 587 VVEAVRELLAEG--EGTIAVICKTAREAEALYA-ALKAGLPVTLIDD 630
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
23-71 |
2.65e-13 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 67.13 E-value: 2.65e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 517408677 23 PLLIVAGAGSGKTAVLTRRIAYLLTQRGVAPWQILAITFTNKAAAEMKE 71
Cdd:cd17914 1 LSLIQGPPGTGKTRVLVKIVAALMQNKNGEPGRILLVTPTNKAAAQLDN 49
|
|
| recB |
PRK10876 |
exonuclease V subunit beta; Provisional |
179-652 |
4.77e-13 |
|
exonuclease V subunit beta; Provisional
Pssm-ID: 236784 [Multi-domain] Cd Length: 1181 Bit Score: 73.08 E-value: 4.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 179 VEYQKRLRESnaLDFDDLIGEVVRIFKQH--PQVTDYYRRRFRHVLVDEYQDTNHAQYELVHTLVGEGPDApELAVVGDS 256
Cdd:PRK10876 339 VAQEKRRRGE--LGFDDLLSRLDSALQSEggEALAAAIRTRYPVAMIDEFQDTDPQQYRIFRRIYRHQPET-ALLLIGDP 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 257 DQSIYAFRGATI----RNIEEFERDYPaaktilLEQNYRSTQNILEAANAVISQ--------------------NEGRR- 311
Cdd:PRK10876 416 KQAIYAFRGADIftymKARSEVSAHYT------LDTNWRSAPGMVNSVNKLFSQtddpflfreipfipvkaagkNQALRf 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 312 --------PKNLWTDHGSGdkiVGyVADNEHDEARFIANEV-DSLA--DQG------------VNYSDIAVMYRTNNASR 368
Cdd:PRK10876 490 vvkgetqpAMKFWLMEGEG---VG-VGDYQQTMAQQCAAQIrDWLQagQRGeallmngddsrpVRASDITVLVRSRQEAA 565
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 369 AVEDIFIRSGIPyKVVGGTR--FYERKEIRDIIAYLRVIDNPDDTVSLRRIVnvpkraigdkAQAMVALHAdnndisfgk 446
Cdd:PRK10876 566 LIRDALTLLAIP-SVYLSNRdsVFETLEAQEMLWLLQAVLAPERERTLRSAL----------ATSMMGLDA--------- 625
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 447 ALIDA---SEGRVDMLatraknaitgfVDMMDTLRAELPSmtnevTG-MPDLGQLVS--RIlditgykAE-LEASndpQD 519
Cdd:PRK10876 626 LDIDAlnnDERAWDAL-----------VEEFDGYRQIWRK-----RGvLPMLRALMSarNI-------AEnLLAT---AG 679
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 520 GARldNLNELVSVArEFSSEAANQMayqveadaDLTSSVGR---AEIVEADdgePEPGSLQAFLErvslvadadqipdNE 596
Cdd:PRK10876 680 GER--RLTDILHIG-ELLQEASSQL--------DSEHALVRwlaQQILEPD---SQASSQQLRLE-------------SD 732
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517408677 597 QGVVTLMTLHTAKGLEFPVV---FVTGW--EDGQFPH----------LRALGDPAELAEERRLA------YVGITRA 652
Cdd:PRK10876 733 KHLVQIVTIHKSKGLEYPLVwlpFITNFrvQDQAFYHdrhsfeavldLNAAEESVALAEEERLAedlrllYVALTRS 809
|
|
| COG3972 |
COG3972 |
Superfamily I DNA and RNA helicases [Replication, recombination and repair]; |
576-682 |
1.10e-11 |
|
Superfamily I DNA and RNA helicases [Replication, recombination and repair];
Pssm-ID: 443172 [Multi-domain] Cd Length: 565 Bit Score: 68.32 E-value: 1.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 576 LQAFLER---VSLVADADQIPDNEQ--GVVTLMTLHTAKGLEFPVVFVTGwedgqfphLRALGDPAELAEERRLAYVGIT 650
Cdd:COG3972 460 LAAALERqgiDSYIAGARSDPNFFWkdGGVTISTIHRAKGLEAPVVIIVG--------LDQLAKGESLERLRNLLYVAMT 531
|
90 100 110
....*....|....*....|....*....|..
gi 517408677 651 RAREKLYLSramlrsswgnSVTNPASRFLAEI 682
Cdd:COG3972 532 RARGWLVVS----------GSGESMAELYDEL 553
|
|
| DExxQc_SF1-N |
cd17914 |
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members ... |
216-290 |
1.43e-11 |
|
DEXQ-box helicase domain of superfamily 1 helicase; The superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Like SF2, they do not form toroidal, predominantly hexameric structures like SF3-6. Their helicase core is surrounded by C and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains or domains engaged in protein-protein interactions. SF1 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438706 [Multi-domain] Cd Length: 121 Bit Score: 62.12 E-value: 1.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 216 RRFRHVLVDEYQDTNHAQYELVHTLVgegPDAPELAVVGDSDQSIYAFRGATIRNIEE-----FERDYPAAKTILLEQNY 290
Cdd:cd17914 45 AQLDNILVDEAAQILEPETSRLIDLA---LDQGRVILVGDHDQLGPVWRGAVLAKICNeqslfTRLVRLGVSLIRLQVQY 121
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
13-72 |
4.67e-11 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 61.08 E-value: 4.67e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517408677 13 QTAAVE--HSGSPLLIVAGAGSGKTAVLTRRIAYLLtQRGVAPWQILAITFTNKAAAEMKER 72
Cdd:pfam13245 1 QREAVRtaLPSKVVLLTGGPGTGKTTTIRHIVALLV-ALGGVSFPILLAAPTGRAAKRLSER 61
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
600-658 |
2.43e-09 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 53.73 E-value: 2.43e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 517408677 600 VTLMTLHTAKGLEFPVVFVTgweDGQFPhlralgDPAELAEERRLAYVGITRAREKLYL 658
Cdd:pfam13538 2 AYALTVHKAQGSEFPAVFLV---DPDLT------AHYHSMLRRRLLYTAVTRARKKLVL 51
|
|
| helD |
PRK11054 |
DNA helicase IV; Provisional |
603-658 |
8.80e-08 |
|
DNA helicase IV; Provisional
Pssm-ID: 182930 [Multi-domain] Cd Length: 684 Bit Score: 55.73 E-value: 8.80e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517408677 603 MTLHTAKGLEFPVVFVTGWEDGQ--FP------HL-RALGDPAEL---AEERRLAYVGITRAREKLYL 658
Cdd:PRK11054 592 MTIHASKGQQADYVIILGLQEGQdgFPaparesIMeEALLPPPEDfpdAEERRLLYVALTRAKHRVWL 659
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
600-658 |
3.35e-07 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 48.59 E-value: 3.35e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 517408677 600 VTLMTLHTAKGLEFPVVFVTgwedgqfphlralgDPAELAEERRLAYVGITRAREKLYL 658
Cdd:cd18786 43 VGAITIDSSQGLTFDVVTLY--------------LPTANSLTPRRLYVALTRARKRLVI 87
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
603-658 |
1.10e-06 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 46.79 E-value: 1.10e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 517408677 603 MTLHTAKGLEFPVVFVtgwedgqfphlrALGDPAELAEeRRLAYVGITRAREKLYL 658
Cdd:cd18809 36 MTIHKSQGSEFDRVIV------------VLPTSHPMLS-RGLLYTALTRARKLLTL 78
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
563-678 |
5.44e-06 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 49.59 E-value: 5.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517408677 563 IVEADDgePEPGSLQAFLERVSLVA-DADQIPDneqgvVTL---MTLHTAKGLEFPVVFVtgwedgqfphlrALGDPAEL 638
Cdd:COG0507 408 TVLSID--EDEGRLTVRFDGREIVTyDPSELDQ-----LELayaITVHKSQGSTFDRVIL------------VLPSEHSP 468
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 517408677 639 AEERRLAYVGITRAREK--LYLSRAMLRSswgnSVTNPASRF 678
Cdd:COG0507 469 LLSRELLYTALTRARELltLVGDRDALAR----AVRRDTARA 506
|
|
| DEAD-like_helicase_N |
cd17912 |
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase ... |
24-89 |
1.13e-05 |
|
N-terminal helicase domain of the DEAD-box helicase superfamily; The DEAD-like helicase superfamily is a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. The N-terminal domain contains the ATP-binding region.
Pssm-ID: 350670 [Multi-domain] Cd Length: 81 Bit Score: 44.05 E-value: 1.13e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517408677 24 LLIVAGAGSGKTAVLTRRIAYLLTqrgvAPWQILAITFTNKAAAEMKERV--SSLIGPQAERMWVATF 89
Cdd:cd17912 2 ILHLGPTGSGKTLVAIQKIASAMS----SGKSVLVVTPTKLLAHEILIVIdeIQ*ILDPAAGWAWATR 65
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
4-71 |
3.85e-05 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 46.89 E-value: 3.85e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517408677 4 DLTLGLNPQQTAAVEH--SGSPLLIVAG-AGSGKTAVLtRRIAYLLTQRGvapWQILAITFTNKAAAEMKE 71
Cdd:COG0507 120 RAGITLSDEQREAVALalTTRRVSVLTGgAGTGKTTTL-RALLAALEALG---LRVALAAPTGKAAKRLSE 186
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
8-71 |
1.39e-04 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 43.71 E-value: 1.39e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517408677 8 GLNPQQTAAVEH---SGSPL-LIVAGAGSGKTAVLtRRIAYLLTQRGvapWQILAITFTNKAAAEMKE 71
Cdd:pfam13604 1 TLNAEQAAAVRAlltSGDRVaVLVGPAGTGKTTAL-KALREAWEAAG---YRVIGLAPTGRAAKVLGE 64
|
|
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