|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
7-460 |
6.28e-143 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 413.80 E-value: 6.28e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 7 ETLVTEIRQLDKKGSGQAVVWRENVFgnpkklkltIPQTLPGEKVRVVADRPEKRRIKAIPEEILEAHPERIAPACPHFD 86
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVF---------VPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 87 RCGGCVWQHWQYQGQLNQKTAHVKEAIASQGFDPEL-VRYTIGMDEPWHYRNKMEFTFAPDGS---MGLHEQGNfRKIIS 162
Cdd:COG2265 72 RCGGCQLQHLSYEAQLELKQRVVREALERIGGLPEVeVEPIIGSPEPWGYRNRARLSVRRTDGrlrLGFYARGS-HELVD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 163 LETCLIAGTEMVEAAMEVAAWVKEHGLkgydkdlHEGLFRHLMVRqsfatgemmlalfateapagdlvqaardltdrieh 242
Cdd:COG2265 151 IDECPLLDPALNALLPALRELLAELGA-------RRGELRHLVVR----------------------------------- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 243 kfpyvksliwlentqwadrtqaekthvlSGRDFIYDEMGGYRYRIWFDTFFQTNPVQAQKLVDLAIEMGQPKKAEKMIDL 322
Cdd:COG2265 189 ----------------------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDL 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 323 FCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEvLESFGNPDLLLLDPPRSGAGGKV 402
Cdd:COG2265 241 YCGVGTFALPLARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPE-LLWGGRPDVVVLDPPRAGAGPEV 319
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 517491078 403 MRKIGRAKPQRIVYVSCNPDTFATDIKELEPFGYQLTAVQPVDLFPHTVHVECCALLV 460
Cdd:COG2265 320 LEALAALGPRRIVYVSCNPATLARDLALLVEGGYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
16-454 |
6.04e-109 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 329.47 E-value: 6.04e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 16 LDKKGSGQAVVWRENVFgnpkklkltIPQTLPGEKVRVVADRPEKRRIKAIPEEILEAHPERIAPACPHFDRCGGCVWQH 95
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVF---------VPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQH 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 96 WQYQGQLNQKTAHVKEAIASQG-FDPELVRY--TIGmDEPWHYRNKMEFT--FAPDGS--MGLHEQGNFRkIISLETCLI 168
Cdd:TIGR00479 72 LSYELQLRSKQQQVIALLERIGkFVSEPIEDvpTIG-DDPWGYRNKARLSlgRSPSGQlqAGFYQKGSHD-IVDVKQCPV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 169 AGTEMVEAAMEVAAWVKEHGLKGYDKDLHEGLFRHLMVRQSFATGEMMLALFATEAPAGDLVQAARDLTDRiehkFPYVK 248
Cdd:TIGR00479 150 QAPALNALLPKVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPD----SPDVK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 249 SLIWLENTQWADRTQAEKTHVLSGRDFIYDEMGGYRYRIWFDTFFQTNPVQAQKLVDLAIEMGQPKKAEKMIDLFCGVGT 328
Cdd:TIGR00479 226 SICQNINPEKTNVIFGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 329 FSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEVLESFGNPDLLLLDPPRSGAGGKVMRKIGR 408
Cdd:TIGR00479 306 FTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIK 385
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 517491078 409 AKPQRIVYVSCNPDTFATDIKELEPFGYQLTAVQPVDLFPHTVHVE 454
Cdd:TIGR00479 386 LKPERIVYVSCNPATLARDLEALCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
7-458 |
8.13e-72 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 233.90 E-value: 8.13e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 7 ETLVTEIRQLDKKGSGQAvvwREN---VFgnpkklkltIPQTLPGEKVRVVADRpEKRRI-KAIPEEILEAHPERIAPAC 82
Cdd:PRK13168 14 QIITVTIESLDHDGRGVA---RHNgktVF---------IEGALPGERVEVQVTE-DKKQYaRAKVVRILKPSPERVTPRC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 83 PHFDRCGGCVWQHWQYQGQLNQKTAHVKEAIA-SQGFDPELVRYTIgMDEPWHYRNKMEFT--FAPDG---SMGLHEQGN 156
Cdd:PRK13168 81 PHFGVCGGCQLQHLSIDAQIASKQRALEDLLKhLAGVEPEEVLPPI-AGPPWGYRRRARLSvrYVPKKgqlLVGFREKNS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 157 fRKIISLETCLIAGTEMVEAAMEVAAWVkeHGLKGYDK----DLHEG------LFRHlmvrqsfatgemMLALfateaPA 226
Cdd:PRK13168 160 -SDIVDIDQCPVLVPPLSALLPPLRALL--SSLSAKRRlghvELAQGdngtalVLRH------------LEPL-----SE 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 227 GDLvQAARDLTDriEHKFpyvksLIWLEntqwadrTQAEKTHVLSGRDfiyDEMGGYRYRIW-----FD--TFFQTNPVQ 299
Cdd:PRK13168 220 ADR-AKLRAFAE--QHGL-----QLYLQ-------PKGPDLVHLLGPA---DAQLSYYLPEFglrlaFSprDFIQVNAQV 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 300 AQKLVDLAIEMGQPKKAEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDarkgIDEV 379
Cdd:PRK13168 282 NQKMVARALEWLDPQPGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHAN----LEED 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 380 L-------ESFgnpDLLLLDPPRSGAGGkVMRKIGRAKPQRIVYVSCNPDTFATDIKELEPFGYQLTAVQPVDLFPHTVH 452
Cdd:PRK13168 358 FtdqpwalGGF---DKVLLDPPRAGAAE-VMQALAKLGPKRIVYVSCNPATLARDAGVLVEAGYRLKRAGMLDMFPHTGH 433
|
....*.
gi 517491078 453 VECCAL 458
Cdd:PRK13168 434 VESMAL 439
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
97-459 |
8.87e-28 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 113.69 E-value: 8.87e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 97 QYQGQLNQKTAHVKEAIAS-QGFDPELVRytigmDEPWHYRNKMEFTFAPDGSMGLH---EQGNFRKIIsLETCLIAgTE 172
Cdd:pfam05958 1 QYDAQLAEKKSRLKALFAPfYAPDPEVFA-----SPDKHYRMRAEFRIWHEGDDLYYamfDQQTKSRIR-VDQFPAA-SE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 173 MVEAAME--VAAWVKEHGLkgydkdlheglfRHLMVRQSFAT---GEMMLALFATEAPAGDLVQAARDLTDRIEHKFPYV 247
Cdd:pfam05958 74 LINELMPalIAALRQDPAL------------RHKLFQVDFLTtlsGEALVSLLYHKQLDDEWRQAAEALRDALRAQGLDV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 248 kSLIwlentqwadrTQAEKTHVLSGRDFIYDEM--GG--YRYRIWFDTFFQTNPVQAQKLVDLAIEMGQPKKAEkMIDLF 323
Cdd:pfam05958 142 -NLI----------GRARKQKIVLDQDYVDETLpvAGreFIYRQVENSFTQPNAAVNIKMLEWACDVTQGSKGD-LLELY 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 324 CGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDAR---------------KGIDevLESFgNPDL 388
Cdd:pfam05958 210 CGNGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEeftqamngvrefnrlKGID--LKSY-NCST 286
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517491078 389 LLLDPPRSGAGGKVMrKIGRAKPqRIVYVSCNPDTFATDIKELEPfGYQLTAVQPVDLFPHTVHVECCALL 459
Cdd:pfam05958 287 IFVDPPRAGLDPETL-KLVQAYP-RILYISCNPETLCANLEQLSK-THRVERFALFDQFPYTHHMECGVLL 354
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
318-419 |
1.78e-07 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 49.35 E-value: 1.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 318 KMIDLFCGVGTFSLPFADRVGKLV-GIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEVLESFgnpDLLLLDPPRS 396
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVtGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESF---DVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 517491078 397 GAGGKVMRKIGRA----KPQRIVYVSC 419
Cdd:cd02440 78 HLVEDLARFLEEArrllKPGGVLVLTL 104
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
7-460 |
6.28e-143 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 413.80 E-value: 6.28e-143
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 7 ETLVTEIRQLDKKGSGQAVVWRENVFgnpkklkltIPQTLPGEKVRVVADRPEKRRIKAIPEEILEAHPERIAPACPHFD 86
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVF---------VPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFG 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 87 RCGGCVWQHWQYQGQLNQKTAHVKEAIASQGFDPEL-VRYTIGMDEPWHYRNKMEFTFAPDGS---MGLHEQGNfRKIIS 162
Cdd:COG2265 72 RCGGCQLQHLSYEAQLELKQRVVREALERIGGLPEVeVEPIIGSPEPWGYRNRARLSVRRTDGrlrLGFYARGS-HELVD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 163 LETCLIAGTEMVEAAMEVAAWVKEHGLkgydkdlHEGLFRHLMVRqsfatgemmlalfateapagdlvqaardltdrieh 242
Cdd:COG2265 151 IDECPLLDPALNALLPALRELLAELGA-------RRGELRHLVVR----------------------------------- 188
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 243 kfpyvksliwlentqwadrtqaekthvlSGRDFIYDEMGGYRYRIWFDTFFQTNPVQAQKLVDLAIEMGQPKKAEKMIDL 322
Cdd:COG2265 189 ----------------------------AGRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDL 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 323 FCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEvLESFGNPDLLLLDPPRSGAGGKV 402
Cdd:COG2265 241 YCGVGTFALPLARRAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPE-LLWGGRPDVVVLDPPRAGAGPEV 319
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 517491078 403 MRKIGRAKPQRIVYVSCNPDTFATDIKELEPFGYQLTAVQPVDLFPHTVHVECCALLV 460
Cdd:COG2265 320 LEALAALGPRRIVYVSCNPATLARDLALLVEGGYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
16-454 |
6.04e-109 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 329.47 E-value: 6.04e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 16 LDKKGSGQAVVWRENVFgnpkklkltIPQTLPGEKVRVVADRPEKRRIKAIPEEILEAHPERIAPACPHFDRCGGCVWQH 95
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVF---------VPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQH 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 96 WQYQGQLNQKTAHVKEAIASQG-FDPELVRY--TIGmDEPWHYRNKMEFT--FAPDGS--MGLHEQGNFRkIISLETCLI 168
Cdd:TIGR00479 72 LSYELQLRSKQQQVIALLERIGkFVSEPIEDvpTIG-DDPWGYRNKARLSlgRSPSGQlqAGFYQKGSHD-IVDVKQCPV 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 169 AGTEMVEAAMEVAAWVKEHGLKGYDKDLHEGLFRHLMVRQSFATGEMMLALFATEAPAGDLVQAARDLTDRiehkFPYVK 248
Cdd:TIGR00479 150 QAPALNALLPKVRAILENFGASRYLEHKELGQARHGVLRIGRHTGELSSVDRTALERFPHKEELDLYLQPD----SPDVK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 249 SLIWLENTQWADRTQAEKTHVLSGRDFIYDEMGGYRYRIWFDTFFQTNPVQAQKLVDLAIEMGQPKKAEKMIDLFCGVGT 328
Cdd:TIGR00479 226 SICQNINPEKTNVIFGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGT 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 329 FSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEVLESFGNPDLLLLDPPRSGAGGKVMRKIGR 408
Cdd:TIGR00479 306 FTLPLAKQAKSVVGVEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIK 385
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 517491078 409 AKPQRIVYVSCNPDTFATDIKELEPFGYQLTAVQPVDLFPHTVHVE 454
Cdd:TIGR00479 386 LKPERIVYVSCNPATLARDLEALCKAGYTIARVQPVDMFPHTGHVE 431
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
7-458 |
8.13e-72 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 233.90 E-value: 8.13e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 7 ETLVTEIRQLDKKGSGQAvvwREN---VFgnpkklkltIPQTLPGEKVRVVADRpEKRRI-KAIPEEILEAHPERIAPAC 82
Cdd:PRK13168 14 QIITVTIESLDHDGRGVA---RHNgktVF---------IEGALPGERVEVQVTE-DKKQYaRAKVVRILKPSPERVTPRC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 83 PHFDRCGGCVWQHWQYQGQLNQKTAHVKEAIA-SQGFDPELVRYTIgMDEPWHYRNKMEFT--FAPDG---SMGLHEQGN 156
Cdd:PRK13168 81 PHFGVCGGCQLQHLSIDAQIASKQRALEDLLKhLAGVEPEEVLPPI-AGPPWGYRRRARLSvrYVPKKgqlLVGFREKNS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 157 fRKIISLETCLIAGTEMVEAAMEVAAWVkeHGLKGYDK----DLHEG------LFRHlmvrqsfatgemMLALfateaPA 226
Cdd:PRK13168 160 -SDIVDIDQCPVLVPPLSALLPPLRALL--SSLSAKRRlghvELAQGdngtalVLRH------------LEPL-----SE 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 227 GDLvQAARDLTDriEHKFpyvksLIWLEntqwadrTQAEKTHVLSGRDfiyDEMGGYRYRIW-----FD--TFFQTNPVQ 299
Cdd:PRK13168 220 ADR-AKLRAFAE--QHGL-----QLYLQ-------PKGPDLVHLLGPA---DAQLSYYLPEFglrlaFSprDFIQVNAQV 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 300 AQKLVDLAIEMGQPKKAEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDarkgIDEV 379
Cdd:PRK13168 282 NQKMVARALEWLDPQPGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVTFYHAN----LEED 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 380 L-------ESFgnpDLLLLDPPRSGAGGkVMRKIGRAKPQRIVYVSCNPDTFATDIKELEPFGYQLTAVQPVDLFPHTVH 452
Cdd:PRK13168 358 FtdqpwalGGF---DKVLLDPPRAGAAE-VMQALAKLGPKRIVYVSCNPATLARDAGVLVEAGYRLKRAGMLDMFPHTGH 433
|
....*.
gi 517491078 453 VECCAL 458
Cdd:PRK13168 434 VESMAL 439
|
|
| meth_trns_rumB |
TIGR02085 |
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases ... |
82-461 |
9.78e-47 |
|
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 131140 Cd Length: 374 Bit Score: 165.78 E-value: 9.78e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 82 CPHFD--RCGGCVWQHWQYQGQLNQKTAHVKEAIASQGFDPELVRYTIGMDEPwhYRNKMEFTF-----APDGSMgLHEQ 154
Cdd:TIGR02085 2 CAFYIqgRCRSCQWLAQPYSEQLTNKQQHLKELLAPNATVVQWLAPVTSAEQA--FRNKAKMVVsgsveRPILGI-LHRD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 155 GNfrkIISLETCLIAGTEMVEAAMEVAAWVKEHGLKGYDKDLHEGLFRHLMVRQSFATGEMMLALFA-TEApagDLVQAA 233
Cdd:TIGR02085 79 GT---PLDLCDCPLYPQSFQPVFAYLKNFIARAGLTPYNVAKKKGELKFILLTESENSGQLMLRFVLrSET---KLAQIR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 234 RDLTDRIEhKFPYVKSLIWLENTQWADRTQAEKTHVLSGRDFIYDEMGGYRYRIWFDTFFQTNPVQAQKLVDLAIEMGQP 313
Cdd:TIGR02085 153 RALPWLIE-QLPQLEVISVNIQPVHMAILEGEEEIFLTEQQALPERFNDVPLVIRPQSFFQTNPKVAAQLYATARQWVRE 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 314 KKAEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKgideVLESFGN-PDLLLLD 392
Cdd:TIGR02085 232 IPVTQMWDLFCGVGGFGLHCAGPDTQLTGIEIESEAIACAQQSAQMLGLDNLSFAALDSAK----FATAQMSaPELVLVN 307
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517491078 393 PPRSGAGGKVMRKIGRAKPQRIVYVSCNPDTFATDIKELEpfGYQLTAVQPVDLFPHTVHVECCALLVL 461
Cdd:TIGR02085 308 PPRRGIGKELCDYLSQMAPKFILYSSCNAQTMAKDIAELS--GYQIERVQLFDMFPHTSHYEVLTLLVR 374
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
151-462 |
1.77e-44 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 158.11 E-value: 1.77e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 151 LHEQGnfrKIISLETCLIAGTEMVEAAMEVAAWVKEHGLKGYDKDLHEGLFRHLMVRQSFATGEMMLALFA-TEAPagdL 229
Cdd:PRK03522 15 LHRDG---TPVDLCDCPLYPASFAPVFAALKPFIARAGLTPYNVARKRGELKYILLTESQSDGELMLRFVLrSETK---L 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 230 VQAARDLtDRIEHKFPYVK--SLiwleNTQ--WADRTQAEKTHVLSGRDFIYDEMGGYRYRIWFDTFFQTNPVQAQKLVD 305
Cdd:PRK03522 89 ARLRRAL-PWLQAQLPQLKviSV----NIQpvHMAILEGEEEIFLTEQQALPERFNGVPLFIRPQSFFQTNPAVAAQLYA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 306 LAIEMGQPKKAEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIdevLESFGN 385
Cdd:PRK03522 164 TARDWVRELPPRSMWDLFCGVGGFGLHCATPGMQLTGIEISAEAIACAKQSAAELGLTNVQFQALDSTQFA---TAQGEV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517491078 386 PDLLLLDPPRSGAGGKVMRKIGRAKPQRIVYVSCNPDTFATDIKELEpfGYQLTAVQPVDLFPHTVHVECCALLVLN 462
Cdd:PRK03522 241 PDLVLVNPPRRGIGKELCDYLSQMAPRFILYSSCNAQTMAKDLAHLP--GYRIERVQLFDMFPHTAHYEVLTLLVRQ 315
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
88-460 |
6.45e-35 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 133.42 E-value: 6.45e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 88 CGGCVWQHwQYQGQLNQKTAHVKEAIAS-QGFDPELVRytigmDEPWHYRNKMEFTF---APDGSMGLHEQGNfRKIISL 163
Cdd:PRK05031 2 TPECLPPE-QYEAQLAEKVARLKELFAPfSAPEPEVFR-----SPPSHYRMRAEFRIwheGDDLYYAMFDQQT-KQRIRI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 164 ETCLIAgTEMVEAAMEV--AAWVKEHglkgydkDLHEGLFrhlmvrQ----SFATGEMMLALF----ATEApagdLVQAA 233
Cdd:PRK05031 75 DQFPIA-SELINALMPAllAALRANP-------VLRHKLF------QvdflSTLSGEILVSLLyhkkLDEE----WEQAA 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 234 RDLTDRiehkfpyvksliwLENTQWADRtqAEKTHVLSGRDFIYDEM--GG--YRYRIWFDTFFQTNPVQAQKLVDLAIE 309
Cdd:PRK05031 137 KALRDA-------------LFNVHLIGR--SRKQKIVLDQDYVDERLpvAGreFIYRQVENSFTQPNAAVNEKMLEWALD 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 310 MGQPKKAEkMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDA--------------R-K 374
Cdd:PRK05031 202 ATKGSKGD-LLELYCGNGNFTLALARNFRRVLATEISKPSVAAAQYNIAANGIDNVQIIRMSAeeftqamngvrefnRlK 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 375 GIDevLESFgNPDLLLLDPPRSGAGGKVMRKIGRAKpqRIVYVSCNPDTFATDIKELEPfGYQLTAVQPVDLFPHTVHVE 454
Cdd:PRK05031 281 GID--LKSY-NFSTIFVDPPRAGLDDETLKLVQAYE--RILYISCNPETLCENLETLSQ-THKVERFALFDQFPYTHHME 354
|
....*.
gi 517491078 455 CCALLV 460
Cdd:PRK05031 355 CGVLLE 360
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
97-459 |
8.87e-28 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 113.69 E-value: 8.87e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 97 QYQGQLNQKTAHVKEAIAS-QGFDPELVRytigmDEPWHYRNKMEFTFAPDGSMGLH---EQGNFRKIIsLETCLIAgTE 172
Cdd:pfam05958 1 QYDAQLAEKKSRLKALFAPfYAPDPEVFA-----SPDKHYRMRAEFRIWHEGDDLYYamfDQQTKSRIR-VDQFPAA-SE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 173 MVEAAME--VAAWVKEHGLkgydkdlheglfRHLMVRQSFAT---GEMMLALFATEAPAGDLVQAARDLTDRIEHKFPYV 247
Cdd:pfam05958 74 LINELMPalIAALRQDPAL------------RHKLFQVDFLTtlsGEALVSLLYHKQLDDEWRQAAEALRDALRAQGLDV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 248 kSLIwlentqwadrTQAEKTHVLSGRDFIYDEM--GG--YRYRIWFDTFFQTNPVQAQKLVDLAIEMGQPKKAEkMIDLF 323
Cdd:pfam05958 142 -NLI----------GRARKQKIVLDQDYVDETLpvAGreFIYRQVENSFTQPNAAVNIKMLEWACDVTQGSKGD-LLELY 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 324 CGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDAR---------------KGIDevLESFgNPDL 388
Cdd:pfam05958 210 CGNGNFSLALARNFRKVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEeftqamngvrefnrlKGID--LKSY-NCST 286
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517491078 389 LLLDPPRSGAGGKVMrKIGRAKPqRIVYVSCNPDTFATDIKELEPfGYQLTAVQPVDLFPHTVHVECCALL 459
Cdd:pfam05958 287 IFVDPPRAGLDPETL-KLVQAYP-RILYISCNPETLCANLEQLSK-THRVERFALFDQFPYTHHMECGVLL 354
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
313-418 |
3.09e-09 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 55.50 E-value: 3.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 313 PKKAEKMIDLFCGVGTFSLPFADRVG---KLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKgIDEVLE--SFgnpD 387
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAEELGpnaEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEE-LPELLEddKF---D 76
|
90 100 110
....*....|....*....|....*....|....
gi 517491078 388 LLLLDPP--RSGAGGKVMRKIGRA-KPQRIVYVS 418
Cdd:pfam13847 77 VVISNCVlnHIPDPDKVLQEILRVlKPGGRLIIS 110
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
288-431 |
2.05e-08 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 54.15 E-value: 2.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 288 WFDTF-FQTNPVQAQKLVDLAiemgQPKKAEKMIDLFCGVGTFSLPFADRVG-KLVGIEIVETSIASAKRNAKDNGISNT 365
Cdd:COG0500 2 WDSYYsDELLPGLAALLALLE----RLPKGGRVLDLGCGTGRNLLALAARFGgRVIGIDLSPEAIALARARAAKAGLGNV 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517491078 366 YFLAKDARKGIDEVLESFgnpDLLL-------LDPPRSGAggkVMRKIGRA-KPQRIVYVSCNPDTFATDIKEL 431
Cdd:COG0500 78 EFLVADLAELDPLPAESF---DLVVafgvlhhLPPEEREA---LLRELARAlKPGGVLLLSASDAAAALSLARL 145
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
318-419 |
1.78e-07 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 49.35 E-value: 1.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 318 KMIDLFCGVGTFSLPFADRVGKLV-GIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEVLESFgnpDLLLLDPPRS 396
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVtGVDISPVALELARKAAAALLADNVEVLKGDAEELPPEADESF---DVIISDPPLH 77
|
90 100
....*....|....*....|....*..
gi 517491078 397 GAGGKVMRKIGRA----KPQRIVYVSC 419
Cdd:cd02440 78 HLVEDLARFLEEArrllKPGGVLVLTL 104
|
|
| Trm11 |
COG1041 |
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 ... |
292-452 |
2.52e-07 |
|
tRNA G10 N-methylase Trm11 [Translation, ribosomal structure and biogenesis]; tRNA G10 N-methylase Trm11 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440663 [Multi-domain] Cd Length: 172 Bit Score: 50.33 E-value: 2.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 292 FFQ---TNPVQAQKLVDLAIemgqPKKAEKMIDLFCGVGTFsLPFADRVG-KLVGIEIVETSIASAKRNAKDNGISNTYF 367
Cdd:COG1041 4 FFYpgsLDPRLARALVNLAG----AKEGDTVLDPFCGTGTI-LIEAGLLGrRVIGSDIDPKMVEGARENLEHYGYEDADV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 368 LAKDARKgIDEVLESFgnpDLLLLDPP-----RSGAGG------KVMRKIGR-AKPQ-RIVYVScnPDTFATDIKELepf 434
Cdd:COG1041 79 IRGDARD-LPLADESV---DAIVTDPPygrssKISGEEllelyeKALEEAARvLKPGgRVVIVT--PRDIDELLEEA--- 149
|
170
....*....|....*...
gi 517491078 435 GYQLtavqpVDLFPHTVH 452
Cdd:COG1041 150 GFKV-----LERHEQRVH 162
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
313-409 |
1.55e-06 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 48.65 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 313 PKKAEKMIDLFCGVGTFSLPFADR--VGKLVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEvlESFgnpDLLL 390
Cdd:COG2813 47 EPLGGRVLDLGCGYGVIGLALAKRnpEARVTLVDVNARAVELARANAAANGLENVEVLWSDGLSGVPD--GSF---DLIL 121
|
90 100
....*....|....*....|
gi 517491078 391 LDPP-RsgAGGKVMRKIGRA 409
Cdd:COG2813 122 SNPPfH--AGRAVDKEVAHA 139
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
321-383 |
2.21e-06 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 46.02 E-value: 2.21e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517491078 321 DLFCGVGTFSLPFADRVG-KLVGIEIVETSIASAKRNAKDNGISNTYFLAkDARKgIDEVLESF 383
Cdd:pfam13649 3 DLGCGTGRLTLALARRGGaRVTGVDLSPEMLERARERAAEAGLNVEFVQG-DAED-LPFPDGSF 64
|
|
| Trm5 |
COG2520 |
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 ... |
314-383 |
5.27e-06 |
|
tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]; tRNA G37 N-methylase Trm5 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 442010 [Multi-domain] Cd Length: 333 Bit Score: 48.32 E-value: 5.27e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517491078 314 KKAEKMIDLFCGVGTFSLPFADRVGKLV-GIEIVETSIASAKRNAKDNGISNT-YFLAKDARKGIDEVLESF 383
Cdd:COG2520 179 KPGERVLDMFAGVGPFSIPIAKRSGAKVvAIDINPDAVEYLKENIRLNKVEDRvTPILGDAREVAPELEGKA 250
|
|
| MTS |
pfam05175 |
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ... |
318-394 |
1.44e-05 |
|
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.
Pssm-ID: 428349 [Multi-domain] Cd Length: 170 Bit Score: 45.27 E-value: 1.44e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517491078 318 KMIDLFCGVGTFSLPFADRVGK--LVGIEIVETSIASAKRNAKDNGISNTYFLAKDARKGIDEvlESFgnpDLLLLDPP 394
Cdd:pfam05175 34 KVLDLGCGAGVLGAALAKESPDaeLTMVDINARALESARENLAANGLENGEVVASDVYSGVED--GKF---DLIISNPP 107
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
305-374 |
3.80e-05 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 43.44 E-value: 3.80e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 305 DLAIEMGQPKKAEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGIsNTYFLAKDARK 374
Cdd:COG2226 12 EALLAALGLRPGARVLDLGCGTGRLALALAERGARVTGVDISPEMLELARERAAEAGL-NVEFVVGDAED 80
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
298-372 |
1.11e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 43.77 E-value: 1.11e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517491078 298 VQAQKlvDLAIEMGQPKKAEKMIDLFCGVGTFSLPFADRV---GKLVGIEIVETSIASAKRNAKDNGiSNTYFLAKDA 372
Cdd:PRK08317 4 FRRYR--ARTFELLAVQPGDRVLDVGCGPGNDARELARRVgpeGRVVGIDRSEAMLALAKERAAGLG-PNVEFVRGDA 78
|
|
| RlmK |
COG1092 |
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure ... |
321-394 |
2.45e-04 |
|
23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI [Translation, ribosomal structure and biogenesis]; 23S rRNA G2069 N7-methylase RlmK or C1962 C5-methylase RlmI is part of the Pathway/BioSystem: 23S rRNA modification
Pssm-ID: 440709 [Multi-domain] Cd Length: 392 Bit Score: 43.25 E-value: 2.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 321 DLFCGVGTFSLpFADRVG--KLVGIEIVETSIASAKRNAKDNGISNTY---------FLAKDARKGidevlESFgnpDLL 389
Cdd:COG1092 222 NLFSYTGGFSV-HAAAGGakSVTSVDLSATALEWAKENAALNGLDDRHefvqadafdWLRELAREG-----ERF---DLI 292
|
....*
gi 517491078 390 LLDPP 394
Cdd:COG1092 293 ILDPP 297
|
|
| Methyltransf_15 |
pfam09445 |
RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as ... |
316-397 |
2.79e-04 |
|
RNA cap guanine-N2 methyltransferase; RNA cap guanine-N2 methyltransferases such as Schizosaccharomyces pombe Tgs1 and Giardia lamblia Tgs2 catalyze methylation of the exocyclic N2 amine of 7-methylguanosine.
Pssm-ID: 370496 Cd Length: 165 Bit Score: 41.55 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 316 AEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTYFLAK-DARKGIDEVLESFGNPDLLLLDPP 394
Cdd:pfam09445 1 ATRILDVFCGGGGNTIQFANVFDSVISIDINLEHLACAQHNAEVYGVSDRIWLIHgDWFELLAKLKFEKIKYDCVFASPP 80
|
...
gi 517491078 395 RSG 397
Cdd:pfam09445 81 WGG 83
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
320-390 |
2.91e-04 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 40.77 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 320 IDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISntyFLAKDAR------KGID-----EVLESFGNPDL 388
Cdd:COG2227 29 LDVGCGTGRLALALARRGADVTGVDISPEALEIARERAAELNVD---FVQGDLEdlpledGSFDlvicsEVLEHLPDPAA 105
|
..
gi 517491078 389 LL 390
Cdd:COG2227 106 LL 107
|
|
| HsdM |
COG0286 |
Type I restriction-modification system, DNA methylase subunit [Defense mechanisms]; |
303-401 |
9.44e-04 |
|
Type I restriction-modification system, DNA methylase subunit [Defense mechanisms];
Pssm-ID: 440055 [Multi-domain] Cd Length: 243 Bit Score: 40.94 E-value: 9.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 303 LVDLAIEMGQPKKAEKMIDLFCGVGTFSLPFADRVGK----------LVGIEIVETSIASAKRNAKDNGISNTYFLAKDA 372
Cdd:COG0286 31 VVRLMVELLDPKPGETVYDPACGSGGFLVEAAEYLKEhggderkklsLYGQEINPTTYRLAKMNLLLHGIGDPNIELGDT 110
|
90 100
....*....|....*....|....*....
gi 517491078 373 RKGIDEVLESFgnpDLLLLDPPRSGAGGK 401
Cdd:COG0286 111 LSNDGDELEKF---DVVLANPPFGGKWKK 136
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
301-355 |
1.04e-03 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 39.98 E-value: 1.04e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 517491078 301 QKLVDLAIEMGQPKKAEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKR 355
Cdd:COG4976 32 ALLAEELLARLPPGPFGRVLDLGCGTGLLGEALRPRGYRLTGVDLSEEMLAKARE 86
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
305-394 |
1.48e-03 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 39.50 E-value: 1.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517491078 305 DLAIEMGQPKKAEKMIDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGISNTY--FLAKDARKGIDEvlES 382
Cdd:PRK14968 13 FLLAENAVDKKGDRVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNNGveVIRSDLFEPFRG--DK 90
|
90
....*....|..
gi 517491078 383 FgnpDLLLLDPP 394
Cdd:PRK14968 91 F---DVILFNPP 99
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
320-363 |
2.20e-03 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 37.26 E-value: 2.20e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 517491078 320 IDLFCGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGIS 363
Cdd:pfam08241 1 LDVGCGTGLLTELLARLGARVTGVDISPEMLELAREKAPREGLT 44
|
|
| PRK07580 |
PRK07580 |
Mg-protoporphyrin IX methyl transferase; Validated |
324-383 |
2.27e-03 |
|
Mg-protoporphyrin IX methyl transferase; Validated
Pssm-ID: 236059 [Multi-domain] Cd Length: 230 Bit Score: 39.44 E-value: 2.27e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517491078 324 CGVGTFSLPFADRVGKLVGIEIVETSIASAKRNAKDNGIS-NTYFLAKDarkgIDEVLESF 383
Cdd:PRK07580 72 CGVGSLSIPLARRGAKVVASDISPQMVEEARERAPEAGLAgNITFEVGD----LESLLGRF 128
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
313-364 |
2.80e-03 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 39.36 E-value: 2.80e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 517491078 313 PKKAEKMIDLFCGVGTFSLPFADRVG--KLVGIEIVETSIASAKRNAKDNGISN 364
Cdd:COG4123 35 VKKGGRVLDLGTGTGVIALMLAQRSPgaRITGVEIQPEAAELARRNVALNGLED 88
|
|
| |
