|
Name |
Accession |
Description |
Interval |
E-value |
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
31-436 |
3.91e-97 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 297.64 E-value: 3.91e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 31 IHLYVAEGGIALILVYLLVFYRKIVKPMSTIGSGMELLREQDFSSRLSLVGQYEADRIVNIFNRMMEQLKNERLRMREQN 110
Cdd:COG5000 10 LLLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREELEERR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 111 HFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHIDSPLA-----EELASIPKEQTSVVRLNDANI 185
Cdd:COG5000 90 RYLETILENLPAGVIVLDADGRITLANPAAERLLGIPLEELIGKPLEELLPELDlaellREALERGWQEEIELTRDGRRT 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 186 YKCTHSSFIDRGFkhpFFLIERMTDEVMKAEKRAYGKVIRMIAHEVNNTTAGITSTLDTVEQALS--TEEGMEDICDVMR 263
Cdd:COG5000 170 LLVRASPLRDDGY---VIVFDDITELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLAdkLEEDREDLERALD 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 264 VCTERCFSMSRFITRFADVVKIPESTLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNII 343
Cdd:COG5000 247 TIIRQVDRLKRIVDEFLDFARLPEPQLEPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLL 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 344 KNAAESIESagaaasrQGEITVKTIAP---ASIEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGLVFIREVLSRHGCTF 420
Cdd:COG5000 327 KNAIEAIEE-------GGEIEVSTRREdgrVRIEVSDNGPGIPEEVLERIFEPFFTTKPKGTGLGLAIVKKIVEEHGGTI 399
|
410
....*....|....*.
gi 517497730 421 SLRTYSDGMTRFRILF 436
Cdd:COG5000 400 ELESRPGGGTTFTIRL 415
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
105-436 |
2.18e-52 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 179.66 E-value: 2.18e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 105 RMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHI---DSPLAEELASIPKEQTSV---- 177
Cdd:COG3852 1 ALRESEELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLSAEELLGRPLAELfpeDSPLRELLERALAEGQPVtere 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 178 VRLNDAN----IYKCTHSSFIDRGFKHPFFLI-------ERMTDEVMKAEK-RAYGKVIRMIAHEVNNTTAGITSTLDTV 245
Cdd:COG3852 81 VTLRRKDgeerPVDVSVSPLRDAEGEGGVLLVlrditerKRLERELRRAEKlAAVGELAAGLAHEIRNPLTGIRGAAQLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 246 EQALSTEEGMEDIcDVMRVCTERcfsMSRFITRFADVVKIPESTLAPVRLNELVSMCKRFMEGMCnDRNIALRLECDPEV 325
Cdd:COG3852 161 ERELPDDELREYT-QLIIEEADR---LNNLVDRLLSFSRPRPPEREPVNLHEVLERVLELLRAEA-PKNIRIVRDYDPSL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 326 GEVRLDASLFEQVLVNIIKNAAESIESAG-----AAASRQGEITVKTIA-PASIEIVDNGPGISKETEAKLFSPFFSTKP 399
Cdd:COG3852 236 PEVLGDPDQLIQVLLNLVRNAAEAMPEGGtitirTRVERQVTLGGLRPRlYVRIEVIDNGPGIPEEILDRIFEPFFTTKE 315
|
330 340 350
....*....|....*....|....*....|....*..
gi 517497730 400 NGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:COG3852 316 KGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYL 352
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
206-436 |
3.91e-41 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 149.56 E-value: 3.91e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 206 ERMTDEVMKAEKRAY-GKVIRMIAHEVNNTTAGITSTLDTVEQALSTEEGMEDICDVMRVCTERCFSMSRFITRFADVVK 284
Cdd:COG4191 127 RELQEQLVQSEKLAAlGELAAGIAHEINNPLAAILGNAELLRRRLEDEPDPEELREALERILEGAERAAEIVRSLRAFSR 206
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 285 IPESTLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAESIESagaaaSRQGEIT 364
Cdd:COG4191 207 RDEEEREPVDLNELIDEALELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIDAMEE-----GEGGRIT 281
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517497730 365 VKTIAP---ASIEIVDNGPGISKETEAKLFSPFFSTKPNGQ--GIGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:COG4191 282 ISTRREgdyVVISVRDNGPGIPPEVLERIFEPFFTTKPVGKgtGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITL 358
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
202-436 |
8.00e-32 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 123.86 E-value: 8.00e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 202 FFLIERMTDEVMKAEKRAYGKVIRMIAHEVNNTTAGITSTLDTVEQALSTEegMEDICDVMRVCTERcfsMSRFITRFAD 281
Cdd:COG0642 92 LLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEELDEE--QREYLETILRSADR---LLRLINDLLD 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 282 VVKIPESTLA----PVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAEsiesagaAA 357
Cdd:COG0642 167 LSRLEAGKLElepePVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIK-------YT 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 358 SRQGEITVKTIAP---ASIEIVDNGPGISKETEAKLFSPFFSTKP----NGQGIGLVFIREVLSRHGCTFSLRTYSDGMT 430
Cdd:COG0642 240 PEGGTVTVSVRREgdrVRISVEDTGPGIPPEDLERIFEPFFRTDPsrrgGGTGLGLAIVKRIVELHGGTIEVESEPGKGT 319
|
....*.
gi 517497730 431 RFRILF 436
Cdd:COG0642 320 TFTVTL 325
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
40-417 |
2.49e-31 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 126.24 E-value: 2.49e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 40 IALILVYLLVfyRKIVKPMSTIGSGMELLrEQDFSSRL-SLVGqyEADRIVNIFNRMMEQLknerlrmREQNHFLDLLIQ 118
Cdd:PRK11360 202 IGLLLIFLLS--RRFSANVDIIKDGLSTL-ENDLSTRLpPLPG--ELGEISQAINNLAQAL-------RETRSLNELILE 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 119 ASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRrleHIDS--PLAEELASIpkeqtsvvrLNDANIYKCTHssfIDR 196
Cdd:PRK11360 270 SIADGVIAIDRQGKITTMNPAAEVITGLQRHELVGK---PYSElfPPNTPFASP---------LLDTLEHGTEH---VDL 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 197 GFKHPFF-----------------------------LIE--RMTDEVMKAEKRA-YGKVIRMIAHEVNNTTAGITSTLDT 244
Cdd:PRK11360 335 EISFPGRdrtielsvstsllhnthgemigalvifsdLTErkRLQRRVARQERLAaLGELVAGVAHEIRNPLTAIRGYVQI 414
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 245 VEQALSTEEGMEDICDVMRVCTercfSMSRFITRFADVVKIPESTLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPE 324
Cdd:PRK11360 415 WRQQTSDPPSQEYLSVVLREVD----RLNKVIDQLLEFSRPRESQWQPVSLNALVEEVLQLFQTAGVQARVDFETELDNE 490
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 325 VGEVRLDASLFEQVLVNIIKNAAESIesagaaaSRQGEITVKTIAPAS----IEIVDNGPGISKETEAKLFSPFFSTKPN 400
Cdd:PRK11360 491 LPPIWADPELLKQVLLNILINAVQAI-------SARGKIRIRTWQYSDgqvaVSIEDNGCGIDPELLKKIFDPFFTTKAK 563
|
410
....*....|....*..
gi 517497730 401 GQGIGLVFIREVLSRHG 417
Cdd:PRK11360 564 GTGLGLALSQRIINAHG 580
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
205-436 |
1.24e-28 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 112.69 E-value: 1.24e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 205 IERMTDEVMKAEkRAYGKVIRMIAHEVNNTTAGITSTLDTVEQALS-TEEGMEDICDVMRVCTERcfsMSRFITRFADVV 283
Cdd:COG2205 2 LEEALEELEELE-RLKSEFLANVSHELRTPLTSILGAAELLLDEEDlSPEERRELLEIIRESAER---LLRLIEDLLDLS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 284 KIPESTL----APVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAEsiesagaAASR 359
Cdd:COG2205 78 RLESGKLslelEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIK-------YSPP 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 360 QGEITVKTIAP---ASIEIVDNGPGISKETEAKLFSPFF----STKPNGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRF 432
Cdd:COG2205 151 GGTITISARREgdgVRISVSDNGPGIPEEELERIFERFYrgdnSRGEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTF 230
|
....
gi 517497730 433 RILF 436
Cdd:COG2205 231 TVTL 234
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
88-417 |
2.46e-25 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 107.75 E-value: 2.46e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 88 IVNIFNRmmeQLKNERLRMREQNHFLdlLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRL---------EH 158
Cdd:COG5809 123 SRDITER---KRMEEALRESEEKFRL--IFNHSPDGIIVTDLDGRIIYANPAACKLLGISIEELIGKSIlelihsddqEN 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 159 IDSPLAEELASIPKEQTSVVRL--NDANIYKCTHSSFIDRGFKHPFFLI-------ERMTDEVM-KAEKraYGKVIRM-- 226
Cdd:COG5809 198 VAAFISQLLKDGGIAQGEVRFWtkDGRWRLLEASGAPIKKNGEVDGIVIifrditeRKKLEELLrKSEK--LSVVGELaa 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 227 -IAHEVNNTTAGITSTLDtVEQALSTEEGMEDIcDVMRVCTERcfsMSRFITRFADVVKIPESTLAPVRLNELVSMCKRF 305
Cdd:COG5809 276 gIAHEIRNPLTSLKGFIQ-LLKDTIDEEQKTYL-DIMLSELDR---IESIISEFLVLAKPQAIKYEPKDLNTLIEEVIPL 350
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 306 MEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAESIESagaaasrQGEITVKTIAPA----SIEIVDNGPG 381
Cdd:COG5809 351 LQPQALLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPE-------GGNITIETKAEDddkvVISVTDEGCG 423
|
330 340 350
....*....|....*....|....*....|....*.
gi 517497730 382 ISKETEAKLFSPFFSTKPNGQGIGLVFIREVLSRHG 417
Cdd:COG5809 424 IPEERLKKLGEPFYTTKEKGTGLGLMVSYKIIEEHG 459
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
69-436 |
3.72e-25 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 107.51 E-value: 3.72e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 69 REQDFSSRLSLVGQYEADRIVNIFNRMMEQLKNERLrMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRR 148
Cdd:COG5805 116 ELIYVEVKLFPIYNQNGQAAILALRDITKKKKIEEI-LQEQEERLQTLIENSPDLICVIDTDGRILFINESIERLFGAPR 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 149 EDAQGRRL-EHIDSPLAEELAS-------IPKEQTSVVRLNDAN----IYKCTHSSFIDRGFKHPFFLI-------ERMT 209
Cdd:COG5805 195 EELIGKNLlELLHPCDKEEFKEriesiteVWQEFIIEREIITKDgrirYFEAVIVPLIDTDGSVKGILVilrditeKKEA 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 210 DEVM-KAEK-RAYGKVIRMIAHEVNNTtagITSTLDTVEQALSTEEGMEDICDVMRVCTERcfsMSRFITRFADVVKIPE 287
Cdd:COG5805 275 EELMaRSEKlSIAGQLAAGIAHEIRNP---LTSIKGFLQLLQPGIEDKEEYFDIMLSELDR---IESIISEFLALAKPQA 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 288 STLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAESIESAGaaasrqgEITVKT 367
Cdd:COG5805 349 VNKEKENINELIQDVVTLLETEAILHNIQIRLELLDEDPFIYCDENQIKQVFINLIKNAIEAMPNGG-------TITIHT 421
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517497730 368 IAPAS---IEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:COG5805 422 EEEDNsviIRVIDEGIGIPEERLKKLGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITL 493
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
204-436 |
1.43e-21 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 96.36 E-value: 1.43e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 204 LIERMTDEVMKAEKRAYGKVIRMIAHEVNNTTAGITSTLDTVEQALSTEEGmEDICDVMRVCTERcfsMSRFITRFADVV 283
Cdd:COG5808 225 LLERVIQEINTQKLELIGTFAASTAHEIRNPLTSIKGFIQLLQEKYPELED-QKYFDIIQEEIQR---INQIVSEFLVLG 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 284 KIPESTLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAESIESAGaaasrqgEI 363
Cdd:COG5808 301 KPTAKKLELDDLNELIEEILSIIDSEANLKNIRVEKQSLDEPLHIKCDKDRIKQVLLNLIKNAIEAMKEGG-------KL 373
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517497730 364 TVkTIAP----ASIEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:COG5808 374 TI-SIENddekAVIEVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIESEEGKGTTFTIRL 449
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
210-434 |
2.40e-20 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 92.93 E-value: 2.40e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 210 DEVMKAEK-RAYGKVIRMIAHEVNNTTAGITSTLDTVEQalSTEEGMED--ICDVMRVCTERcfsMSRFITRFADVVKIP 286
Cdd:PRK10364 226 DEMKRKEKlVALGHLAAGVAHEIRNPLSSIKGLAKYFAE--RAPAGGEAhqLAQVMAKEADR---LNRVVSELLELVKPT 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 287 ESTLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAESIesagaaaSRQGEITVK 366
Cdd:PRK10364 301 HLALQAVDLNDLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAI-------GQHGVISVT 373
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517497730 367 -TIAPASIEIV--DNGPGISKETEAKLFSPFFSTKPNGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRI 434
Cdd:PRK10364 374 aSESGAGVKISvtDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTL 444
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
40-436 |
1.37e-19 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 89.91 E-value: 1.37e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 40 IALILVYLLVFYRKIVKPMSTIGSGMELLreqdFSSRLSLVGQYEADRIVNIFNRMMEQLKNERLRMREQNhflDLLIQA 119
Cdd:COG3290 20 ILLLLLLIILLLILLLVLLLLLFLLFVII----LLLLLLILLLILLLLLLLLLAALLLKLLEEIARLVEER---EAVLES 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 120 SPMGLVIMTLDGEVSQLNPMAVKMLGIrreDAQGRRLEHIDSPLAEElasipKEQTSVVRLNDaNIYKCTHSSFIDRGFK 199
Cdd:COG3290 93 IREGVIAVDRDGRITLINDAARRLLGL---DAIGRPIDEVLAEVLET-----GERDEEILLNG-RVLVVNRVPIRDDGRV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 200 HPFFLIERMTDEVMKAEK-----RAYGKVIRMIAHEVNNTTAGITSTLDT--VEQALsteEGMEDICDVMRVCTERcfsm 272
Cdd:COG3290 164 VGAVATFRDRTELERLEEelegvKELAEALRAQRHDFRNHLHTISGLLQLgeYDEAL---EYIDEISEELQELIDS---- 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 273 srfitrfaDVVKIPESTLAPVrLNELVSMCKrfmegmcnDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAaesIES 352
Cdd:COG3290 237 --------LLSRIGNPVLAAL-LLGKAARAR--------ERGIDLTIDIDSDLPDLPLSDTDLVTILGNLLDNA---IEA 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 353 AGAAASRQGEITVKTIAPAS---IEIVDNGPGISKETEAKLFSPFFSTKP-NGQGIGLVFIREVLSRHGCTFSLRTYSDG 428
Cdd:COG3290 297 VEKLPEEERRVELSIRDDGDelvIEVEDSGPGIPEELLEKIFERGFSTKLgEGRGLGLALVKQIVEKYGGTIEVESEEGE 376
|
....*...
gi 517497730 429 MTRFRILF 436
Cdd:COG3290 377 GTVFTVRL 384
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
65-436 |
1.73e-19 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 89.61 E-value: 1.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 65 MELLREQDFSSRLSLVGQYEADRIVNIFNRMMEQLKNERLRMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKML 144
Cdd:COG5002 16 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 145 GIRREDAQGRRLEHIDSPLAEELASIPKEQTSVVRLNDANIYKCTHSSFIDRGFKHPFFLIERMTDEVMKAEkraygkVI 224
Cdd:COG5002 96 LLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRRE------FV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 225 RMIAHEVNNTTAGITSTLDTV-EQALSTEEGMEDICDVMRVCTERcfsMSRFITRFADVVKIPESTL----APVRLNELV 299
Cdd:COG5002 170 ANVSHELRTPLTSIRGYLELLlDGAADDPEERREYLEIILEEAER---LSRLVNDLLDLSRLESGELklekEPVDLAELL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 300 SMCKRFMEGMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAEsiesagaAASRQGEITVKTIAPAS---IEIV 376
Cdd:COG5002 247 EEVVEELRPLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIK-------YTPEGGTITVSLREEDDqvrISVR 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517497730 377 DNGPGISKETEAKLFSPFF------STKPNGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:COG5002 320 DTGIGIPEEDLPRIFERFYrvdksrSRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITL 385
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-433 |
4.50e-18 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 79.36 E-value: 4.50e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 336 EQVLVNIIKNAAESIeSAGAAASRQGEITVKTIAPAS--IEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGLVFIREVL 413
Cdd:cd16920 2 QQVLINLVRNGIEAM-SEGGCERRELTIRTSPADDRAvtISVKDTGPGIAEEVAGQLFDPFYTTKSEGLGMGLSICRSII 80
|
90 100
....*....|....*....|
gi 517497730 414 SRHGCTFSLRTYSDGMTRFR 433
Cdd:cd16920 81 EAHGGRLSVESPAGGGATFQ 100
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
333-435 |
1.24e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 77.85 E-value: 1.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 333 SLFEQVLVNIIKNAAESIEsagaaasRQGEITVKT---IAPASIEIVDNGPGISKETEAKLFSPFFSTKPNGQ--GIGLV 407
Cdd:cd16943 2 SQLNQVLLNLLVNAAQAME-------GRGRITIRTwahVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPVGEgtGLGLS 74
|
90 100
....*....|....*....|....*...
gi 517497730 408 FIREVLSRHGCTFSLRTYSDGMTRFRIL 435
Cdd:cd16943 75 LSYRIIQKHGGTIRVASVPGGGTRFTII 102
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-435 |
1.63e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 77.83 E-value: 1.63e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 336 EQVLVNIIKNAAEsiesagAAASRQGEITVKTIA-------------PASIEIVDNGPGISKETEAKLFSPFFSTKPNGQ 402
Cdd:cd16918 2 IQVFLNLVRNAAQ------ALAGSGGEIILRTRTqrqvtlghprhrlALRVSVIDNGPGIPPDLQDTIFYPMVSGRENGT 75
|
90 100 110
....*....|....*....|....*....|...
gi 517497730 403 GIGLVFIREVLSRHGCTFSLrTYSDGMTRFRIL 435
Cdd:cd16918 76 GLGLAIAQNIVSQHGGVIEC-DSQPGHTVFSVS 107
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-436 |
6.24e-17 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 76.04 E-value: 6.24e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 331 DASLFEQVLVNIIKNAAESIEsagAAASRQGEITVKTIAPA----SIEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGL 406
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIE---GRPSDVGEVRIRVEADQdgriVLIVCDNGKGFPREMRHRATEPYVTTRPKGTGLGL 77
|
90 100 110
....*....|....*....|....*....|
gi 517497730 407 VFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:cd16944 78 AIVKKIMEEHGGRISLSNREAGGACIRIIL 107
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
331-436 |
3.29e-16 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 74.22 E-value: 3.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 331 DASLFEQVLVNIIKNAAEsiesagaAASRQGEITV---KTIAPASIEIVDNGPGISKETEAKLFSPFFSTKPN-----GQ 402
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIK-------YTPEGGRITVtleRDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDKRsrkigGT 74
|
90 100 110
....*....|....*....|....*....|....
gi 517497730 403 GIGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:smart00387 75 GLGLSIVKKLVELHGGEISVESEPGGGTTFTITL 108
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
331-436 |
3.30e-15 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 71.25 E-value: 3.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 331 DASLFEQVLVNIIKNAAESIESAGaaasrQGEITVKTIAPASIEIVDNGPGISKETEAKLFSPFFS---TKPNGQGIGLV 407
Cdd:pfam02518 2 DELRLRQVLSNLLDNALKHAAKAG-----EITVTLSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTadkRGGGGTGLGLS 76
|
90 100
....*....|....*....|....*....
gi 517497730 408 FIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:pfam02518 77 IVRKLVELLGGTITVESEPGGGTTVTLTL 105
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
287-434 |
1.40e-14 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 75.87 E-value: 1.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 287 ESTLAPVRLNELVSMCKRFMEgMCNDRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAESIESAG--------AAAS 358
Cdd:PRK13837 514 ERNTKPFDLSELVTEIAPLLR-VSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMDGAGrvdislsrAKLR 592
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517497730 359 RQGEITVKTIAP---ASIEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRI 434
Cdd:PRK13837 593 APKVLSHGVLPPgryVLLRVSDTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRGTRFDV 671
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
207-416 |
2.50e-14 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 73.96 E-value: 2.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 207 RMTDEVMK-AEKRAYGKVIRMIAHEVNNTTAGITSTLDTVEQALSTEEGME------DICDVMRVCTERCFSMSRFITrf 279
Cdd:PRK11073 116 RLSQEQLQhAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEytkviiEQADRLRNLVDRLLGPQRPGT-- 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 280 advvKIPESTLAPV-RLNELVSMckrfmegMCNDrNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAESIESAGaaas 358
Cdd:PRK11073 194 ----HVTESIHKVAeRVVQLVSL-------ELPD-NVRLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEG---- 257
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517497730 359 rqGEITVKT--------------IApASIEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGLVFIREVLSRH 416
Cdd:PRK11073 258 --GTITLRTrtafqltlhgeryrLA-ARIDIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQH 326
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-434 |
6.69e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 67.48 E-value: 6.69e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 336 EQVLVNIIKNAAESIESAG-----AAASRQGEITVKTIApasieivDNGPGISKETEAKLFSPFFSTKP--NGQGIGLVF 408
Cdd:cd16976 2 QQVLMNLLQNALDAMGKVEnprirIAARRLGGRLVLVVR-------DNGPGIAEEHLSRVFDPFFTTKPvgKGTGLGLSI 74
|
90 100
....*....|....*....|....*.
gi 517497730 409 IREVLSRHGCTFSLRTYSDGMTRFRI 434
Cdd:cd16976 75 SYGIVEEHGGRLSVANEEGAGARFTF 100
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
208-417 |
3.10e-13 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 71.64 E-value: 3.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 208 MTDEVMKAEKRAY-GKVIRMIAHEVNNTTAGITSTLDTVEQALSTE--EGMEDICDVMRVCTERcfsMSRFITRFADVVK 284
Cdd:COG4192 420 TQDELIQAAKMAVvGQTMTSLAHELNQPLNAMSMYLFSAKKALEQEnyAQLPTSLDKIEGLIER---MDKIIKSLRQFSR 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 285 IPESTLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVgevRLDASLFEQVLVNIIKNAAEsiesagaAASRQGEIT 364
Cdd:COG4192 497 KSDTPLQPVDLRQVIEQAWELVESRAKPQQITLHIPDDLMV---QGDQVLLEQVLVNLLVNALD-------AVATQPQIS 566
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 517497730 365 VKTIAPA---SIEIVDNGPGIskETEAKLFSPFFSTKPNGQGIGLVFIREVLSRHG 417
Cdd:COG4192 567 VDLLSNAenlRVAISDNGNGW--PLVDKLFTPFTTTKEVGLGLGLSICRSIMQQFG 620
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
306-406 |
3.88e-12 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 67.58 E-value: 3.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 306 MEGMCNDRNIALRLECDPEVgEVRLDASLFEQVLVNIIKNAAESIESAG----AAASRQGEITvktiapasIEIVDNGPG 381
Cdd:COG5806 284 LSPYANMNNVEIQTELEPGL-YIEGDRQKLQQCLINIIKNGIEAMPNGGtltiDVSIDKNKVI--------ISIKDTGVG 354
|
90 100
....*....|....*....|....*
gi 517497730 382 ISKETEAKLFSPFFSTKPNGQGIGL 406
Cdd:COG5806 355 MTKEQLERLGEPYFSTKEKGTGLGT 379
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
210-406 |
2.08e-11 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 65.85 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 210 DEVMKAEK-RAYGKVIRMIAHEVNNTTAGITSTLDTVEQALSTEEG----MEDICDVMRVCTERCFSMSRFITRFADVVK 284
Cdd:PRK13557 152 DALRQAQKmEALGQLTGGIAHDFNNLLQVMSGYLDVIQAALSHPDAdrgrMARSVENIRAAAERAATLTQQLLAFARKQR 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 285 IPESTlapVRLNELVS----MCKRFMEGmcndrNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAE--------SIES 352
Cdd:PRK13557 232 LEGRV---LNLNGLVSgmgeLAERTLGD-----AVTIETDLAPDLWNCRIDPTQAEVALLNVLINARDampeggrvTIRT 303
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 517497730 353 AGAAASRQGEITVKTIAP---ASIEIVDNGPGISKETEAKLFSPFFSTKPNGQGIGL 406
Cdd:PRK13557 304 RNVEIEDEDLAMYHGLPPgryVSIAVTDTGSGMPPEILARVMDPFFTTKEEGKGTGL 360
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
295-434 |
1.05e-10 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 63.90 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 295 LNELVSMCKRFMEGMCNDRNIALRLEcdPEVGEVRLDASLFEQVLVNIIKNAaesIESAGAAAsrqgEITVKTIAPA--- 371
Cdd:PRK10490 741 LEEVVGSALQMLEPGLSGHPINLSLP--EPLTLIHVDGPLFERVLINLLENA---VKYAGAQA----EIGIDAHVEGerl 811
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517497730 372 SIEIVDNGPGISKETEAKLFSPFF-----STKPnGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRI 434
Cdd:PRK10490 812 QLDVWDNGPGIPPGQEQLIFDKFArgnkeSAIP-GVGLGLAICRAIVEVHGGTIWAENRPEGGACFRV 878
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
287-417 |
1.66e-10 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 62.88 E-value: 1.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 287 ESTLAPVRLNELVSMCKRFMEGMCNDRNIALRLECDPEVgevRLDASLFEQVLVNIIKNAAESiesagAAASRQGEITVK 366
Cdd:COG4251 350 ELEFEPVDLNELLEEVLEDLEPRIEERGAEIEVGPLPTV---RGDPTLLRQVFQNLISNAIKY-----SRPGEPPRIEIG 421
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 517497730 367 TIAPAS---IEIVDNGPGISKETEAKLFSPFF----STKPNGQGIGLVFIREVLSRHG 417
Cdd:COG4251 422 AEREGGewvFSVRDNGIGIDPEYAEKIFEIFQrlhsRDEYEGTGIGLAIVKKIVERHG 479
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
335-406 |
2.72e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 54.69 E-value: 2.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 335 FEQVLVNIIKNAAEsiesagaAASRQGEITVKT---------------IAPA---SIEIVDNGPGISKETEAKLFSPFFS 396
Cdd:cd16919 1 LELAILNLAVNARD-------AMPEGGRLTIETsnqrvdadyalnyrdLIPGnyvCLEVSDTGSGMPAEVLRRAFEPFFT 73
|
90
....*....|
gi 517497730 397 TKPNGQGIGL 406
Cdd:cd16919 74 TKEVGKGTGL 83
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
207-417 |
2.79e-09 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 58.42 E-value: 2.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 207 RMTDE--VMKAEKRAYGK-------VIRMIAHEVNN--TTAGIT-STLDTVEQALSTEEGMEDICDVMRVCTERCFSMSR 274
Cdd:PRK09303 129 QLSDElfVLRQENETLLEqlkfkdrVLAMLAHDLRTplTAASLAlETLELGQIDEDTELKPALIEQLQDQARRQLEEIER 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 275 FITRFADVVKIPESTLA--PVRLNeLVSMCKRFMEGMCN---DRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAAES 349
Cdd:PRK09303 209 LITDLLEVGRTRWEALRfnPQKLD-LGSLCQEVILELEKrwlAKSLEIQTDIPSDLPSVYADQERIRQVLLNLLDNAIKY 287
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517497730 350 IESagaaasrQGEITV----KTIAPASIEIVDNGPGISKETEAKLFSPFF----STKPNGQGIGLVFIREVLSRHG 417
Cdd:PRK09303 288 TPE-------GGTITLsmlhRTTQKVQVSICDTGPGIPEEEQERIFEDRVrlprDEGTEGYGIGLSVCRRIVRVHY 356
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
105-428 |
3.50e-09 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 58.76 E-value: 3.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 105 RMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRR-LEHIDSPLAEELASIPKEQtSVVRLNDA 183
Cdd:TIGR02938 124 VVANQKLLIESVVDAAPVAFVLLDPTGRVILDNQEYKKLATDLRVKEPAHTvLDLLREAWREALAENWPQQ-LAFSNREA 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 184 NI----------YKCTHSSF-IDRGFKHPFF-------LIERMTD-----------------------EVMKAEKRAYGK 222
Cdd:TIGR02938 203 RFdrgggrparwLSCTGSVIgMESDCADSFFcaaeqpyLLLTIADisnlreeqerarlsalqalmaeeERLEAIRETLSA 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 223 VIRMIAHEVN------------NTTAGITSTLDTVEQALSTeeGMEDICDVmrvctERCFSMSrfitrfadvvkiPESTL 290
Cdd:TIGR02938 283 AIHRLQGPMNlisaaisvlqrrGDDAGNPASAAMLQQALSA--GREHMEAL-----RQVIPQS------------PQEIV 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 291 APVRLNEL------VSMCKRFMEGMCNDRNIALRLecdPEV--GEVRLdASLFEQvlvnIIKNAaesIESAGAAASRQGE 362
Cdd:TIGR02938 344 VPVNLNQIlrdvitLSTPRLLAAGIVVDWQPAATL---PAIlgRELQL-RSLFKA----LVDNA---IEAMNIKGWKRRE 412
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517497730 363 ITVKTIAPAS---IEIVDNGPGISKETEAKLFSPFFSTKPN---GQGIGLVFIREVLSRHGCTFSLRT-YSDG 428
Cdd:TIGR02938 413 LSITTALNGDlivVSILDSGPGIPQDLRYKVFEPFFTTKGGsrkHIGMGLSVAQEIVADHGGIIDLDDdYSEG 485
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
341-434 |
2.34e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 51.52 E-value: 2.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 341 NIIKNAaesIESAGAAASRQGEITVKTIAPAS---IEIVDNGPGISKETEAKLFSPFFSTKPNG-QGIGLVFIREVLSRH 416
Cdd:cd16915 7 NLIDNA---LDALAATGAPNKQVEVFLRDEGDdlvIEVRDTGPGIAPELRDKVFERGVSTKGQGeRGIGLALVRQSVERL 83
|
90
....*....|....*...
gi 517497730 417 GCTFSLRTYSDGMTRFRI 434
Cdd:cd16915 84 GGSITVESEPGGGTTFSI 101
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
289-417 |
2.42e-08 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 56.01 E-value: 2.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 289 TLAPVRLNELVsmcKRFMEGMCND---RNIALRLECDPevGEVRLDASLFEQVLVNIIKNAAEsiesagaAASRQGEITV 365
Cdd:PRK11100 325 VLEPVALAALL---EELVEAREAQaaaKGITLRLRPDD--ARVLGDPFLLRQALGNLLDNAID-------FSPEGGTITL 392
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 366 ---KTIAPASIEIVDNGPGISKETEAKLFSPFFST-KPNGQ----GIGLVFIREVLSRHG 417
Cdd:PRK11100 393 saeVDGEQVALSVEDQGPGIPDYALPRIFERFYSLpRPANGrkstGLGLAFVREVARLHG 452
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
312-411 |
2.66e-07 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 52.61 E-value: 2.66e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 312 DRNIALRLECD---PEVGEVRLDASLFeQVLVNIIKNAAESIESAGaaasrQGEITVKTI---APASIEIVDNGPGISKE 385
Cdd:PRK11086 409 ELGITLIISEDsqlPDSGDEDQVHELI-TILGNLIENALEAVGGEE-----GGEISVSLHyrnGWLHCEVSDDGPGIAPD 482
|
90 100
....*....|....*....|....*.
gi 517497730 386 TEAKLFSPFFSTKPNGQGIGLVFIRE 411
Cdd:PRK11086 483 EIDAIFDKGYSTKGSNRGVGLYLVKQ 508
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-428 |
2.70e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 48.61 E-value: 2.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 331 DASLFEQVLVNIIKNA----AESIESAGAAASRQGEITVKtiapasieIVDNGPGISKETEAKLFSPFFS-TKPNGQ--- 402
Cdd:cd16945 1 DPFLLRQAINNLLDNAidfsPEGGLIALQLEADTEGIELL--------VFDEGSGIPDYALNRVFERFYSlPRPHSGqks 72
|
90 100
....*....|....*....|....*..
gi 517497730 403 -GIGLVFIREVLSRHGCTFSLRTYSDG 428
Cdd:cd16945 73 tGLGLAFVQEVAQLHGGRITLRNRPDG 99
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-434 |
2.92e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 48.60 E-value: 2.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 337 QVLVNIIKNAAESiesAGAAASRQGEITVKTIApasIEIVDNGPGISKETEAKLFSPFF----STKPNGQGIGLVFIREV 412
Cdd:cd16950 3 RVLSNLVDNALRY---GGGWVEVSSDGEGNRTR---IQVLDNGPGIAPEEVDELFQPFYrgdnARGTSGTGLGLAIVQRI 76
|
90 100
....*....|....*....|..
gi 517497730 413 LSRHGCTFSLRTYSDGMTRFRI 434
Cdd:cd16950 77 SDAHGGSLTLANRAGGGLCARI 98
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
332-417 |
1.14e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 46.94 E-value: 1.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 332 ASLFEQVLVNIIKNAAESIESAGAAASRQGEITVKtiapasieivDNGPGISKETEAKLFSPFF------STKPNGQGIG 405
Cdd:cd16949 2 ARALENVLRNALRYSPSKILLDISQDGDQWTITIT----------DDGPGVPEDQLEQIFLPFYrvdsarDRESGGTGLG 71
|
90
....*....|..
gi 517497730 406 LVFIREVLSRHG 417
Cdd:cd16949 72 LAIAERAIEQHG 83
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-422 |
1.16e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 47.02 E-value: 1.16e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 331 DASLFEQVLVNIIKNAAESIESAGaaasrQGEITVKTIAPASIEIVDNGPGISKETEAKLFSPFF---STKPNGQGIGLV 407
Cdd:cd16940 10 DALLLFLLLRNLVDNAVRYSPQGS-----RVEIKLSADDGAVIRVEDNGPGIDEEELEALFERFYrsdGQNYGGSGLGLS 84
|
90
....*....|....*
gi 517497730 408 FIREVLSRHGCTFSL 422
Cdd:cd16940 85 IVKRIVELHGGQIFL 99
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
219-434 |
6.90e-06 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 48.58 E-value: 6.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 219 AYGKVIRMIAHEVNNTTAGITSTLDTVE-QALSTEEGMEDICdvMRVCTERcfSMSRFITRFADVVKIPEST--LAP--V 293
Cdd:PRK09959 711 AKSQFLATMSHEIRTPISSIMGFLELLSgSGLSKEQRVEAIS--LAYATGQ--SLLGLIGEILDVDKIESGNyqLQPqwV 786
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 294 RLNELV-SMCKRFmEGMCNDRNIALRLECD-PEVGEVRLDASLFEQVLVNIIKNAAEsIESAGAAASRQGEITVK-TIAP 370
Cdd:PRK09959 787 DIPTLVqNTCHSF-GAIAASKSIALSCSSTfPDHYLVKIDPQAFKQVLSNLLSNALK-FTTEGAVKITTSLGHIDdNHAV 864
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517497730 371 ASIEIVDNGPGISKETEAKLFSPFFST----KPNGQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRI 434
Cdd:PRK09959 865 IKMTIMDSGSGLSQEEQQQLFKRYSQTsagrQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTI 932
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
289-428 |
9.13e-06 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 47.72 E-value: 9.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 289 TLAPVRLNELVSMCKRFMEGMCNDRNIALRLECdPEVGEVRLDASLFEQVLV-NIIKNAAESiesagaaaSRQGEITVKT 367
Cdd:PRK10337 307 DVAEIPLEDLLQSAVMDIYHTAQQAGIDVRLTL-NAHPVIRTGQPLLLSLLVrNLLDNAIRY--------SPQGSVVDVT 377
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517497730 368 IAPASIEIVDNGPGISKETEAKLFSPFFstKPNGQ-----GIGLVFIREVLSRHGCTFSLRTYSDG 428
Cdd:PRK10337 378 LNARNFTVRDNGPGVTPEALARIGERFY--RPPGQeatgsGLGLSIVRRIAKLHGMNVSFGNAPEG 441
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-417 |
1.73e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 43.72 E-value: 1.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 337 QVLVNIIKNAAEsiesagAAASRQGEITVKTIAPAS---IEIVDNGPGISKETEAKLFSPFFSTKPNGQ------GIGLV 407
Cdd:cd16953 3 QVLRNLIGNAIS------FSPPDTGRITVSAMPTGKmvtISVEDEGPGIPQEKLESIFDRFYTERPANEafgqhsGLGLS 76
|
90
....*....|
gi 517497730 408 FIREVLSRHG 417
Cdd:cd16953 77 ISRQIIEAHG 86
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
293-436 |
2.12e-05 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 46.55 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 293 VRLNELVSMCKRFMEGMC---NDRnIALRLECDPEVGEVRlDASLFEQVLV-NIIKNAAESIEsagaaasRQGEITVKTI 368
Cdd:COG2972 297 VTLEEELELIKSYLEIQKlrfGDR-LEVEIEIDEELLDLL-IPKLILQPLVeNAIEHGIEPKE-------GGGTIRISIR 367
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517497730 369 APAS---IEIVDNGPGISKETEAKLFSPfFSTKPNGQGIGLVFIREVLSRH-GCTFSLRTYS--DGMTRFRILF 436
Cdd:COG2972 368 KEGDrlvITVEDNGVGMPEEKLEKLLEE-LSSKGEGRGIGLRNVRERLKLYyGEEYGLEIESepGEGTTVTIRI 440
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
336-434 |
2.48e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 43.19 E-value: 2.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 336 EQVLVNIIKNAAESiesagaaASRQGEITVKTIAPASIEIV-DNGPGISKETEAKLFSPFFSTKPN------GQGIGLVF 408
Cdd:cd16939 2 ARALDNLLRNALRY-------AHRTVRIALLVSGGRLTLIVeDDGPGIPAAARERVFEPFVRLDPSrdratgGFGLGLAI 74
|
90 100
....*....|....*....|....*.
gi 517497730 409 IREVLSRHGCTFSLRTYSDGMTRFRI 434
Cdd:cd16939 75 VHRVALWHGGHVECDDSELGGACFRL 100
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
29-258 |
3.36e-05 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 46.03 E-value: 3.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 29 HSIHLYVAEGGIALILVYLLVFYRKIVKPMSTIGSGMELLREQDFSSRLSLVGQYEADRIVNIFNRMMEQLKNERLRMRE 108
Cdd:COG3850 117 RKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEE 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 109 QNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRRE----DAQGRRLEHIDSPLAEELASIPKEQTSVVRLNDAN 184
Cdd:COG3850 197 EEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAAllllLLLQDALAESELLALNILAGLLELLLALLLLLLAS 276
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517497730 185 IYKCTHSSFIDRGFKHPFFLIERMTDEVMKAEKRAYGKVIRMIAHEVNNTTAGITSTLDTVEQALSTEEGMEDI 258
Cdd:COG3850 277 ALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQ 350
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
102-169 |
3.63e-05 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 45.92 E-value: 3.63e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 102 ERLRMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHI--DSPLAEELAS 169
Cdd:COG3829 2 EELELKELEEELEAILDSLDDGIIVVDADGRITYVNRAAERILGLPREEVIGKNVTELipNSPLLEVLKT 71
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
331-421 |
3.95e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 42.45 E-value: 3.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 331 DASLFEQVLVNIIKNAAESIESAGAAASRQGEItvktiaPASIEIV--DNGPGISKETEAKLFSPFFSTKPN------GQ 402
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQT------PQEVRLDveDSAPGVSDDQLARLFERFYRVESSrnrasgGS 74
|
90
....*....|....*....
gi 517497730 403 GIGLVFIREVLSRHGCTFS 421
Cdd:cd16946 75 GLGLAICHNIALAHGGTIS 93
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
312-433 |
5.65e-05 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 45.36 E-value: 5.65e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 312 DRNIALRLECDPEVGevRLDASLFEQVLVNIIKNAAESIESAGA-AASRQGEItvktiapASIEIVDNGPGISKETEAKL 390
Cdd:PRK10604 299 EKTVRLDTPHQGDYG--ALDMRLMERVLDNLLNNALRYAHSRVRvSLLLDGNQ-------ACLIVEDDGPGIPPEERERV 369
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 517497730 391 FSPFFSTKPN------GQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFR 433
Cdd:PRK10604 370 FEPFVRLDPSrdratgGCGLGLAIVHSIALAMGGSVNCDESELGGARFS 418
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
111-156 |
1.36e-04 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 40.08 E-value: 1.36e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 517497730 111 HFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRL 156
Cdd:smart00091 1 ERLRAILESLPDGIFVLDLDGRILYANPAAEELLGYSPEELIGKSL 46
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
333-436 |
1.48e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 41.03 E-value: 1.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 333 SLFEQVLVNIIKNAAESiesagaaasrqGEITVKTIAP---ASIEIVDNGPGISKETEAKLFSPFF------STKPNGQG 403
Cdd:cd16952 3 SAFSNLVSNAVKYTPPS-----------DTITVRWSQEesgARLSVEDTGPGIPPEHIPRLTERFYrvdierCRNTGGTG 71
|
90 100 110
....*....|....*....|....*....|...
gi 517497730 404 IGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:cd16952 72 LGLAIVKHVMSRHDARLLIASELGKGSRFTCLF 104
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
227-406 |
1.53e-04 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 44.25 E-value: 1.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 227 IAHEVNNTTAGITSTLDTVEQALSTEEGMeDICDVMRVCTercFSMSRFITRFADVVKIpES---TLAPVRLnELVSMCK 303
Cdd:PRK15347 405 ISHEIRTPLNGVLGALELLQNTPLTAEQM-DLADTARQCT---LSLLAIINNLLDFSRI-ESgqmTLSLEET-ALLPLLD 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 304 RFM---EGMCNDRNIALRLECDPEVGEV-RLDASLFEQVLVNIIKNAAESIESagaaasrqGEI--TVKTIAPASIEIV- 376
Cdd:PRK15347 479 QAMltiQGPAQSKSLTLRTFVGAHVPLYlHLDSLRLRQILVNLLGNAVKFTET--------GGIrlRVKRHEQQLCFTVe 550
|
170 180 190
....*....|....*....|....*....|
gi 517497730 377 DNGPGISKETEAKLFSPFFSTKPNGQGIGL 406
Cdd:PRK15347 551 DTGCGIDIQQQQQIFTPFYQADTHSQGTGL 580
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
331-434 |
1.74e-04 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 40.94 E-value: 1.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 331 DASLFEQVLVNIIKNAAESIESAGAAASRqgeITVKTIAPASIEIVDNGPGISKETEAKLFSPF------FSTKPNGQGI 404
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGRIRCI---LEKFRLNRFLLTVSDSGPGIPPNLREEIFERFrqgdgsSTRAHGGTGL 77
|
90 100 110
....*....|....*....|....*....|
gi 517497730 405 GLVFIREVLSRHGCTFSLRTYSDGMTRFRI 434
Cdd:cd16925 78 GLSIVKEFVELHGGTVTVSDAPGGGALFQV 107
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
335-417 |
2.09e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 40.55 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 335 FEQVLVNIIKNAAESIEsagaaasrQGEITVK--------TIAPASIEIVDNGPGISKETEAKLFSPF------FSTKPN 400
Cdd:cd16922 1 LRQILLNLLGNAIKFTE--------EGEVTLRvsleeeeeDGVQLRFSVEDTGIGIPEEQQARLFEPFsqadssTTRKYG 72
|
90
....*....|....*..
gi 517497730 401 GQGIGLVFIREVLSRHG 417
Cdd:cd16922 73 GTGLGLAISKKLVELMG 89
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
377-436 |
3.63e-04 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 42.59 E-value: 3.63e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517497730 377 DNGPGISKETEAKLFSPFfsTKPN------GQGIGLVFIREVLSRHGCTFSLRTYSDGMTRFRILF 436
Cdd:PRK09467 368 DDGPGIPPEQLKHLFQPF--TRGDsargssGTGLGLAIVKRIVDQHNGKVELGNSEEGGLSARAWL 431
|
|
| HAMP |
pfam00672 |
HAMP domain; |
49-101 |
5.06e-04 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 37.99 E-value: 5.06e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 517497730 49 VFYRKIVKPMSTIGSGMELLREQDFSSRLSLVGQYEADRIVNIFNRMMEQLKN 101
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
97-168 |
5.74e-04 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 41.55 E-value: 5.74e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517497730 97 EQLKNERlRMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHIDSPLAEELA 168
Cdd:COG2202 124 ERKRAEE-ALRESEERLRLLVENAPDGIFVLDLDGRILYVNPAAEELLGYSPEELLGKSLLDLLHPEDRERL 194
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
52-100 |
7.91e-04 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 37.23 E-value: 7.91e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 517497730 52 RKIVKPMSTIGSGMELLREQDFSSRLSLVGQYEADRIVNIFNRMMEQLK 100
Cdd:smart00304 1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLE 49
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
69-434 |
8.70e-04 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 41.81 E-value: 8.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 69 REQDFSSRLSLVGQYEADRIVNIFNRMMEQLKNERLRmreQNHFLDLLIQASPMGLVIMTLDGEVSQL------------ 136
Cdd:PRK11466 278 QDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELR---NQHGLAHLEKASARGQYSLLLLGMVSLCalililwrvvyr 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 137 ---NPMAvkmlgiRREDAQGRRLE-HIDSPLAEelASIPKEQTSVVRLNDA---NIYKCTHSSfidrgfKHPFFLIERMT 209
Cdd:PRK11466 355 svtRPLA------EQTQALQRLLDgDIDSPFPE--TAGVRELDTIGRLMDAfrsNVHALNRHR------EQLAAQVKART 420
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 210 DEVM-----------KAEK--RAYGKVIRMIAHEVNNTTAGITSTLdtveQALSTEEGMEDICDVMRVCTERCFSMSRFI 276
Cdd:PRK11466 421 AELQelviehrqaraEAEKasQAKSAFLAAMSHEIRTPLYGILGTA----QLLADNPALNAQRDDLRAITDSGESLLTIL 496
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 277 TRFADVVKIpESTLAPVRLNE-------LVSMCKRFMEGMCNDRNIALRLE-CDPEVGEVRLDASLFEQVLVNIIKNAAE 348
Cdd:PRK11466 497 NDILDYSAI-EAGGKNVSVSDepfeprpLLESTLQLMSGRVKGRPIRLATDiADDLPTALMGDPRRIRQVITNLLSNALR 575
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 349 SIEsagaaasrQGEITVKTIAPAS---IEIVDNGPGISKETEAKLFSPF--FSTKPNGQGIGLVFIREVLSRHGCTFSLR 423
Cdd:PRK11466 576 FTD--------EGSIVLRSRTDGEqwlVEVEDSGCGIDPAKLAEIFQPFvqVSGKRGGTGLGLTISSRLAQAMGGELSAT 647
|
410
....*....|.
gi 517497730 424 TYSDGMTRFRI 434
Cdd:PRK11466 648 STPEVGSCFCL 658
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
35-101 |
1.13e-03 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 41.16 E-value: 1.13e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517497730 35 VAEGGIALILVYLLVFYRKIVKPMSTIGSGMELLREQDFSSRLSLVGQYEADRIVNIFNRMMEQLKN 101
Cdd:COG0840 187 ALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLRE 253
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
102-162 |
1.22e-03 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 40.39 E-value: 1.22e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517497730 102 ERLRMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHIDSP 162
Cdd:COG2202 2 AEEALEESERRLRALVESSPDAIIITDLDGRILYVNPAFERLTGYSAEELLGKTLRDLLPP 62
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
33-258 |
1.62e-03 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 40.87 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 33 LYVAEGGIALILVYLLVFYRKIVKPMSTIGSGMELLREQDFSSRLSLVGQYEADRIVNIFNRMMEQLK---NERLRMREQ 109
Cdd:COG2770 215 LLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLResiEEAEEEEEL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 110 NHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHIDSPLAEELASIPKEQTSVVRLNDANIYKCT 189
Cdd:COG2770 295 AEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELL 374
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517497730 190 HSSFIDRGFKHPFFLIERMTDEVMKAEKRAYGKVIRMIAHEVNNTTAGITSTLDTVEQALSTEEGMEDI 258
Cdd:COG2770 375 VLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAA 443
|
|
| PAS |
pfam00989 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
112-154 |
1.90e-03 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395786 [Multi-domain] Cd Length: 113 Bit Score: 37.78 E-value: 1.90e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 517497730 112 FLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGR 154
Cdd:pfam00989 2 DLRAILESLPDGIFVVDEDGRILYVNAAAEELLGLSREEVIGK 44
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
33-109 |
2.88e-03 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 40.00 E-value: 2.88e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517497730 33 LYVAEGGIALILVYLLVFYRKIVKPMSTIGSGMELLREQDFSsRLSLVGQYEADRIVNIFNRMMEQLKNERLRMREQ 109
Cdd:COG2972 160 LLIILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV-RLEVSGNDEIGILARSFNEMVERIKELIEEVYEL 235
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
8-436 |
3.72e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 39.50 E-value: 3.72e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 8 FILALLLLGMGGALIYLWGGTHSIHLYVAEGGIALILVYLLVFYRKIVKPMSTIGSGMELLREQDFSSRLSLVGQYEADR 87
Cdd:COG3920 64 AAALAVALAAAVGAAAALLALLVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLLLLLLLLAI 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 88 IVNIFNRMMEQLKNERLRMREQNHFLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHIDSPLAEEL 167
Cdd:COG3920 144 LALAELAVALAELAAALLLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLLLLLLLALL 223
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 168 AS-----------IPKEQTSVVRLNDANIYKCTHSSFID--RGFKHPFFLIERMTDEVMKAEKRAYGKV------IRMIA 228
Cdd:COG3920 224 LVllaallrlraaVLEELERRRRARGLGRLLLLLLLLLLllRALLLLAAGIRLVITERKRAEEELEASLeekellLRELH 303
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 229 HEVNNTTAGITSTLDTveQALSTEEgmEDICDVMRVCTERCFSMSRFITRFADvvkipESTLAPVRLNELVSMCKRFMEG 308
Cdd:COG3920 304 HRVKNNLQVVSSLLRL--QARRADD--PEAREALEESQNRIQALALVHELLYQ-----SEDWEGVDLRDYLRELLEPLRD 374
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 309 MCNDRNIALRLECDPevgeVRLDASLFEQV--LVN-IIKNAAESiesaGAAASRQGEITVK-TIAP--ASIEIVDNGPGI 382
Cdd:COG3920 375 SYGGRGIRIELDGPD----VELPADAAVPLglILNeLVTNALKH----AFLSGEGGRIRVSwRREDgrLRLTVSDNGVGL 446
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 517497730 383 SKETEAklfspffstkPNGQGIGLVFIREVLSRHGCTFSLRTySDGmTRFRILF 436
Cdd:COG3920 447 PEDVDP----------PARKGLGLRLIRALVRQLGGTLELDR-PEG-TRVRITF 488
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-432 |
4.15e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 36.54 E-value: 4.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 337 QVLVNIIKNAaesIESAGAAASRQGEITVKTIA-PASIEIVDNGPGISKETEAKLFSPFFSTKPN----GQGIGLVFIRE 411
Cdd:cd16921 3 QVLTNLLGNA---IKFRRPRRPPRIEVGAEDVGeEWTFYVRDNGIGIDPEYAEKVFGIFQRLHSReeyeGTGVGLAIVRK 79
|
90 100
....*....|....*....|.
gi 517497730 412 VLSRHGCTFSLRTYSDGMTRF 432
Cdd:cd16921 80 IIERHGGRIWLESEPGEGTTF 100
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
312-407 |
4.54e-03 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 39.45 E-value: 4.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 312 DRNIALRLECDPEVGE-VRLDASLFEQVLVNIIKNAAESIEsagaaasrQGEITVKTIAPAS--------IEIVDNGPGI 382
Cdd:PRK11107 385 EKGLELTLNIDPDVPDnVIGDPLRLQQIITNLVGNAIKFTE--------SGNIDILVELRALsntkvqleVQIRDTGIGI 456
|
90 100 110
....*....|....*....|....*....|.
gi 517497730 383 SKETEAKLFSPF------FSTKPNGQGIGLV 407
Cdd:PRK11107 457 SERQQSQLFQAFrqadasISRRHGGTGLGLV 487
|
|
| PAS_8 |
pfam13188 |
PAS domain; PAS domains are involved in many signalling proteins where they are used as a ... |
112-174 |
4.76e-03 |
|
PAS domain; PAS domains are involved in many signalling proteins where they are used as a signal sensor domain. PAS domains appear in archaea, bacteria and eukaryotes. Several PAS-domain proteins are known to detect their signal by way of an associated cofactor. Heme, flavin, and a 4-hydroxycinnamyl chromophore are used in different proteins. This domain recognizes oxygen and CO (Matilla et al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 463802 [Multi-domain] Cd Length: 65 Bit Score: 35.60 E-value: 4.76e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517497730 112 FLDLLIQASPMGLVIMTLDGEVSQLNPMAVKMLGIRREDAQGRRLEHIDSPLAEELASIPKEQ 174
Cdd:pfam13188 2 RLRALFESSPDGILVLDEGGRIIYVNPAALELLGYELLGELLGELLDLLDPLLEDALELLREL 64
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| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
335-437 |
5.71e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 36.49 E-value: 5.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 335 FEQVLVNIIKNAAESiesagaaasrqGEITVK---TIAPASIEIVDNGPGISKETEAKLFSPFFsTKPNGQ------GIG 405
Cdd:cd16948 10 IGQIVSNALKYSKQG-----------GKIEIYsetNEQGVVLSIKDFGIGIPEEDLPRVFDKGF-TGENGRnfqestGMG 77
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90 100 110
....*....|....*....|....*....|..
gi 517497730 406 LVFIREVLSRHGCTFSLRTYSDGMTRFRILFS 437
Cdd:cd16948 78 LYLVKKLCDKLGHKIDVESEVGEGTTFTITFP 109
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| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
227-437 |
6.28e-03 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 38.41 E-value: 6.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 227 IAHEVNNTTAGITSTLDTVEQAlSTEEGMEDI--CDVMRVCTERCFSMSRFITRFA----DVVKIPESTLAPVRlNELVS 300
Cdd:PRK10755 144 VAHELRTPLAGIRLHLELLEKQ-HHIDVAPLIarLDQMMHTVEQLLQLARAGQSFSsghyQTVKLLEDVILPSQ-DELSE 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517497730 301 MCKRfmegmcndRNIALRLECDPEVGEVRLDASLFEQVLVNIIKNAaesiesagaaaSR----QGEITVKTIAP---ASI 373
Cdd:PRK10755 222 MLEQ--------RQQTLLLPESAADITVQGDATLLRLLLRNLVENA-----------HRyspeGSTITIKLSQEdggAVL 282
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517497730 374 EIVDNGPGISKETEAKLFSPF--FSTKPNGQGIGLVFIREVLSRHGCTFSLRTYSDGM-TRFRILFS 437
Cdd:PRK10755 283 AVEDEGPGIDESKCGELSKAFvrMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQERSgTRAWVWLP 349
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