|
Name |
Accession |
Description |
Interval |
E-value |
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
176-466 |
4.15e-67 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 220.19 E-value: 4.15e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 176 VYIYSRWMAMKITNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLEKTEIEKKQLEKSKQRMLVHISH 255
Cdd:COG5002 95 LLLLLALLILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRREFVANVSH 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 256 DLKTPITTIQSYVEALQLGLIKEEARKQQALHTIHTKA-RLvTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEY 334
Cdd:COG5002 175 ELRTPLTSIRGYLELLLDGAADDPEERREYLEIILEEAeRL-SRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEEL 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 335 YSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHiniiddgigipYAVK--- 411
Cdd:COG5002 254 RPLAEEKGIELELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGTITVSLREEDDQVR-----------ISVRdtg 322
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517596982 412 --------EKVFEAFFRGDQSR-KSDGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPK 466
Cdd:COG5002 323 igipeedlPRIFERFYRVDKSRsRETGGTGLGLAIVKHIVEAHGGRIWVESEPGKgTTFTITLPL 387
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
231-467 |
1.23e-63 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 206.30 E-value: 1.23e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 231 KLEKTEIEKKQLEKSKQRMLVHISHDLKTPITTIQSYVEALQLGLIKEEARKQQALHTIHTKARLVTELIEDVFELSKLE 310
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 311 SPDYPFPTDTLDICEFIREIAAEYYSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIE 390
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLAEEKGIRLELDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517596982 391 DTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSdGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPKT 467
Cdd:COG2205 161 EGDGVRISVSDNGPGIPEEELERIFERFYRGDNSRGE-GGTGLGLAIVKRIVEAHGGTIWVESEPGGgTTFTVTLPLA 237
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
240-467 |
4.53e-58 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 194.74 E-value: 4.53e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 240 KQLEKSKQRMLVHISHDLKTPITTIQSYVEALQLGLikeEARKQQALHTIHTKARLVTELIEDVFELSKLESPDYPFPTD 319
Cdd:COG0642 104 EEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEL---DEEQREYLETILRSADRLLRLINDLLDLSRLEAGKLELEPE 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 320 TLDICEFIREIAAEYYSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISL----------I 389
Cdd:COG0642 181 PVDLAELLEEVVELFRPLAEEKGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEGGTVTVSVrregdrvrisV 260
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 390 EDT-QKIhiniiddgigiPYAVKEKVFEAFFRGDQSRKSdGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPKT 467
Cdd:COG0642 261 EDTgPGI-----------PPEDLERIFEPFFRTDPSRRG-GGTGLGLAIVKRIVELHGGTIEVESEPGKgTTFTVTLPLA 328
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
217-466 |
2.29e-30 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 123.36 E-value: 2.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 217 ELMQIQNDFNLMAEKLEKTEIEK-KQLEKSKQRM--LVHI-SHDLKTPITTIQSYVEALQ---LGLIKEEARkqQALHTI 289
Cdd:COG4251 249 ILVLELLELRLELEELEEELEERtAELERSNEELeqFAYVaSHDLREPLRKISGFSQLLEedyGDKLDEEGR--EYLERI 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 290 HTKARLVTELIEDVFELSKLESPDYPFptDTLDICEFIREIAAEYYSLFEEKQFNFQFEiPFQKIYVlfNYTLLYRAVSN 369
Cdd:COG4251 327 RDAAERMQALIDDLLAYSRVGRQELEF--EPVDLNELLEEVLEDLEPRIEERGAEIEVG-PLPTVRG--DPTLLRQVFQN 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 370 VLSNALKYNPEGTN--ILISLIEDTQKIHiniiddgigipYAVK-----------EKVFEAFFRGdQSRKSDGGTGLGLT 436
Cdd:COG4251 402 LISNAIKYSRPGEPprIEIGAEREGGEWV-----------FSVRdngigidpeyaEKIFEIFQRL-HSRDEYEGTGIGLA 469
|
250 260 270
....*....|....*....|....*....|.
gi 517596982 437 ISKHIVEKHGGQIYLHTDEGK-TRFQITLPK 466
Cdd:COG4251 470 IVKKIVERHGGRIWVESEPGEgATFYFTLPK 500
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
235-468 |
1.65e-29 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 119.68 E-value: 1.65e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 235 TEIEKKQLEKSKQRMLVHISHDLKTPITTIQSYVEALQLGLIKE----EARKQQALHTIHTKARLVTELIEDVFELSKLE 310
Cdd:COG5000 190 TELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRKLADKleedREDLERALDTIIRQVDRLKRIVDEFLDFARLP 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 311 SPDYpfptDTLDICEFIREIAAEYYSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIE 390
Cdd:COG5000 270 EPQL----EPVDLNELLREVLALYEPALKEKDIRLELDLDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRR 345
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517596982 391 DTQKIHINIIDDGIGIPYAVKEKVFEAFFrgdqSRKSDgGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPKTG 468
Cdd:COG5000 346 EDGRVRIEVSDNGPGIPEEVLERIFEPFF----TTKPK-GTGLGLAIVKKIVEEHGGTIELESRPGGgTTFTIRLPLAE 419
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
190-465 |
2.98e-27 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 113.96 E-value: 2.98e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 190 PLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLEKTEiekkqleKSKQRMLVHISHDLKTPITTIQSYVE 269
Cdd:PRK10549 191 PVKRLVEGTHKLAAGDFTTRVTPTSRDELGRLAQDFNQLASTLEKNE-------QMRRDFMADISHELRTPLAVLRGELE 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 270 ALQLGLIKEEArkqQALHTIHTKARLVTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEYYSLFEEKQFNFQFEI 349
Cdd:PRK10549 264 AIQDGVRKFTP---ESVASLQAEVGTLTKLVDDLHQLSLSDEGALAYRKTPVDLVPLLEVAGGAFRERFASRGLTLQLSL 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 350 PFQKIYV--------LFNytllyravsNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRG 421
Cdd:PRK10549 341 PDSATVFgdpdrlmqLFN---------NLLENSLRYTDSGGSLHISAEQRDKTLRLTFADSAPGVSDEQLQKLFERFYRT 411
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 517596982 422 DQSR-KSDGGTGLGLTISKHIVEKHGGQIYL-HTDEGKTRFQITLP 465
Cdd:PRK10549 412 EGSRnRASGGSGLGLAICLNIVEAHNGRIIAaHSPFGGVSITVELP 457
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
183-466 |
1.45e-25 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 109.16 E-value: 1.45e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 183 MAMKITNPLRSIADGIRNITNGyyyKRLRF--KSNYELMQIQNDFNLMAEKLE-KTEIEKkqlekskqrmLVH-ISHDLK 258
Cdd:PRK11100 202 VVWWLNRSIRRLTRYADAVTEG---KPVPLpkLGSSELRELAQALESMRVKLEgKAYVEQ----------YVQtLTHELK 268
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 259 TPITTIQSYVEALQLGLikEEARKQQALHTIHTKARLVTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEYYSLF 338
Cdd:PRK11100 269 SPLAAIRGAAELLQEDP--PPEDRARFTGNILTQSARLQQLIDRLLELARLEQRQELEVLEPVALAALLEELVEAREAQA 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 339 EEKQFNFQFEIPfqKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIP-YAVkEKVFEA 417
Cdd:PRK11100 347 AAKGITLRLRPD--DARVLGDPFLLRQALGNLLDNAIDFSPEGGTITLSAEVDGEQVALSVEDQGPGIPdYAL-PRIFER 423
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 517596982 418 FF---RGDQSRKSdggTGLGLTISKHIVEKHGGQIYLH-TDEGKTRFQITLPK 466
Cdd:PRK11100 424 FYslpRPANGRKS---TGLGLAFVREVARLHGGEVTLRnRPEGGVLATLTLPR 473
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
238-466 |
3.80e-25 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 107.40 E-value: 3.80e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 238 EKKQLEKSKQRMLVHISHDLKTPITTIQSYVEALQLGLIkEEARKQQALHTIHTKARLVTELIEDVFELSKLESPDYPFP 317
Cdd:PRK11006 196 QMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMQDQPL-EGALREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDL 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 318 TDTLDICEFIREIAAEYYSLFEEKQfNFQFEIPfQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISL--------- 388
Cdd:PRK11006 275 NEKVDVPMMLRVLEREAQTLSQGKH-TITFEVD-NSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHITVRWqrvpqgaef 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 389 -IEDT------QKIHiniiddgigipyavkeKVFEAFFRGDQSRKSD-GGTGLGLTISKHIVEKHGGQIYLHTDEGK-TR 459
Cdd:PRK11006 353 sVEDNgpgiapEHIP----------------RLTERFYRVDKARSRQtGGSGLGLAIVKHALSHHDSRLEIESEVGKgTR 416
|
....*..
gi 517596982 460 FQITLPK 466
Cdd:PRK11006 417 FSFVLPE 423
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
181-465 |
6.88e-25 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 106.70 E-value: 6.88e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 181 RWMAMKITNPLRSIADGIRNITNGYYYKRLRF-KSNYELMQIQNDFNLMAEKLEktEIEKKQlekskQRMLVHISHDLKT 259
Cdd:TIGR01386 182 WWITRLGLEPLRRLSAVAARISPESLDQRLDPsRAPAELRELAQSFNAMLGRLE--DAFQRL-----SQFSADLAHELRT 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 260 PIT--------------TIQSYVEALQLGLikEEARkqqalhtihtkaRLvTELIEDVFELSKLESPDYPFPTDTLDICE 325
Cdd:TIGR01386 255 PLTnllgqtqvalsqprTGEEYREVLESNL--EELE------------RL-SRMVSDMLFLARADNGQLALERVRLDLAA 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 326 FIREIAAEYYSLFEEKQFNFQFEIpfqKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIG 405
Cdd:TIGR01386 320 ELAKVAEYFEPLAEERGVRIRVEG---EGLVRGDPQMFRRAISNLLSNALRHTPDGGTITVRIERRSDEVRVSVSNPGPG 396
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517596982 406 IPYAVKEKVFEAFFRGDQSRKSDG-GTGLGLTISKHIVEKHGGQIYLHTDEGKTRFQITLP 465
Cdd:TIGR01386 397 IPPEHLSRLFDRFYRVDPARSNSGeGTGLGLAIVRSIMEAHGGRASAESPDGKTRFILRFP 457
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
217-465 |
1.22e-24 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 105.03 E-value: 1.22e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 217 ELMQIQND-FNLMAEKLEKTEiekkQLeKSKQRMLVHISHDLKTPITTIQSYVEALQLGLIKEEARKQQAL-----HTIH 290
Cdd:PRK09303 126 ELLQLSDElFVLRQENETLLE----QL-KFKDRVLAMLAHDLRTPLTAASLALETLELGQIDEDTELKPALieqlqDQAR 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 291 TKARLVTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEYYSLFEEKQFNFQFEIPfQKIYVLFNYTLLYRAV-SN 369
Cdd:PRK09303 201 RQLEEIERLITDLLEVGRTRWEALRFNPQKLDLGSLCQEVILELEKRWLAKSLEIQTDIP-SDLPSVYADQERIRQVlLN 279
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 370 VLSNALKYNPEGTNILISLIEDT-QKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSDgGTGLGLTISKHIVEKHGGQ 448
Cdd:PRK09303 280 LLDNAIKYTPEGGTITLSMLHRTtQKVQVSICDTGPGIPEEEQERIFEDRVRLPRDEGTE-GYGIGLSVCRRIVRVHYGQ 358
|
250
....*....|....*...
gi 517596982 449 IYLHTDEGK-TRFQITLP 465
Cdd:PRK09303 359 IWVDSEPGQgSCFHFTLP 376
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
187-465 |
1.24e-24 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 104.88 E-value: 1.24e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 187 ITNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDfnlmAEKLEKTEIEKKQLekskQRMLVH-------------I 253
Cdd:COG4191 78 LLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERD----ITELERAEEELREL----QEQLVQseklaalgelaagI 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 254 SHDLKTPITTIQSYVEALQ--LGLIKEEARKQQALHTIHTKARLVTELIEDVFELSKLESPDypfpTDTLDICEFIREIA 331
Cdd:COG4191 150 AHEINNPLAAILGNAELLRrrLEDEPDPEELREALERILEGAERAAEIVRSLRAFSRRDEEE----REPVDLNELIDEAL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 332 AEYYSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNAL-----KYNP--------EGTNILISlIEDT-QKIhi 397
Cdd:COG4191 226 ELLRPRLKARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIdameeGEGGritistrrEGDYVVIS-VRDNgPGI-- 302
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 398 niiddgigiPYAVKEKVFEAFFrgdqSRKSDG-GTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:COG4191 303 ---------PPEVLERIFEPFF----TTKPVGkGTGLGLSISYGIVEKHGGRIEVESEPGGgTTFTITLP 359
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
363-464 |
2.84e-24 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 96.52 E-value: 2.84e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSdGGTGLGLTISKHIV 442
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGTIEISLRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSREG-GGTGLGLAIVRRIV 79
|
90 100
....*....|....*....|...
gi 517596982 443 EKHGGQIYLHTDEGK-TRFQITL 464
Cdd:cd00075 80 EAHGGRITVESEPGGgTTFTVTL 102
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
359-467 |
4.25e-24 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 96.56 E-value: 4.25e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 359 NYTLLYRAVSNVLSNALKYNPEGTNILISL----------IEDT-QKIhiniiddgigiPYAVKEKVFEAFFRGDQSRKS 427
Cdd:smart00387 2 DPDRLRQVLSNLLDNAIKYTPEGGRITVTLerdgdhveitVEDNgPGI-----------PPEDLEKIFEPFFRTDKRSRK 70
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 517596982 428 DGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPKT 467
Cdd:smart00387 71 IGGTGLGLSIVKKLVELHGGEISVESEPGGgTTFTITLPLE 111
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
190-468 |
1.51e-22 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 100.23 E-value: 1.51e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 190 PLRSIADGIRNITNGYYYKRLRFKS-NYELMQIQNDFNLMAEKLEktEIEKKQLEKSKQrmlvhISHDLKTPITTIQSYV 268
Cdd:PRK09835 212 PIRSVSRQIQNITSKDLDVRLDPQTvPIELEQLVLSFNHMIERIE--DVFTRQSNFSAD-----IAHEIRTPITNLITQT 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 269 EalqlgLIKEEARKQQALH-----TIHTKARLvTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEYYSLFEEKQF 343
Cdd:PRK09835 285 E-----IALSQSRSQKELEdvlysNLEELTRM-AKMVSDMLFLAQADNNQLIPEKKMLDLADEVGKVFDFFEAWAEERGV 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 344 NFQFEipFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQ 423
Cdd:PRK09835 359 ELRFV--GDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVENPGTPIAPEHLPRLFDRFYRVDP 436
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 517596982 424 SRKSDG-GTGLGLTISKHIVEKHGGQIYLHTDEGKTRFQITLPKTG 468
Cdd:PRK09835 437 SRQRKGeGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLPRLE 482
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
3.35e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 88.21 E-value: 3.35e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSdGGTGLGLTISKHIV 442
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSRNT-EGAGLGLSIAKAII 79
|
90 100
....*....|....*....|...
gi 517596982 443 EKHGGQIYLHTDEGKTRFQITLP 465
Cdd:cd16923 80 ELHGGSASAEYDDNHDLFKVRLP 102
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
203-465 |
7.92e-21 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 94.67 E-value: 7.92e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 203 NGYYYKRLRFKSNYELMQIQNDFNLMAEKLEkteiekkQLEKSKQRMLVHISHDLKTPITTIQsYVEALQLGLIKEEark 282
Cdd:PRK10604 176 DGHLAERIHFDEGSSLERLGVAFNQMADNIN-------ALIASKKQLIDGIAHELRTPLVRLR-YRLEMSDNLSAAE--- 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 283 QQALHtihtkaRLVTEL---IEDVFELSKLESPDYPFPTDTLDICEFIREIAAEYYSLFEEKQFNFqfEIPFQKIYVLFN 359
Cdd:PRK10604 245 SQALN------RDIGQLealIEELLTYARLDRPQNELHLSEPDLPAWLSTHLADIQAVTPEKTVRL--DTPHQGDYGALD 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 360 YTLLYRAVSNVLSNALKYNpeGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSR-KSDGGTGLGLTIS 438
Cdd:PRK10604 317 MRLMERVLDNLLNNALRYA--HSRVRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRdRATGGCGLGLAIV 394
|
250 260
....*....|....*....|....*...
gi 517596982 439 KHIVEKHGGQIYLHTDE-GKTRFQITLP 465
Cdd:PRK10604 395 HSIALAMGGSVNCDESElGGARFSFSWP 422
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
216-465 |
1.51e-19 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 90.76 E-value: 1.51e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 216 YELMQIQNDFNLMAEKLEkteiekkQLEKSKQRMLVHISHDLKTPITTIQsyveaLQLGLIKeeaRKQ---QALHTIHTK 292
Cdd:PRK09470 220 QEFRQAGASFNQMVTALE-------RMMTSQQRLLSDISHELRTPLTRLQ-----LATALLR---RRQgesKELERIETE 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 293 ARLVTELIEDVFELSK------LESPdyPFPTDTL--DICEfireiAAEyyslFEEKQFNFQFEIPFQ--KIYVLFNYTL 362
Cdd:PRK09470 285 AQRLDSMINDLLVLSRnqqknhLERE--TFKANSLwsEVLE-----DAK----FEAEQMGKSLTVSAPpgPWPINGNPNA 353
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNpeGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSR-KSDGGTGLGLTISKHI 441
Cdd:PRK09470 354 LASALENIVRNALRYS--HTKIEVAFSVDKDGLTITVDDDGPGVPEEEREQIFRPFYRVDEARdRESGGTGLGLAIVENA 431
|
250 260
....*....|....*....|....*
gi 517596982 442 VEKHGGQIYLH-TDEGKTRFQITLP 465
Cdd:PRK09470 432 IQQHRGWVKAEdSPLGGLRLTIWLP 456
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
361-467 |
2.04e-19 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 83.19 E-value: 2.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 361 TLLYRAVSNVLSNALKYNPEGTNILISL---------IEDTqkihiniiddGIGIPYAVKEKVFEAFFRGDQSRKsdGGT 431
Cdd:pfam02518 4 LRLRQVLSNLLDNALKHAAKAGEITVTLseggeltltVEDN----------GIGIPPEDLPRIFEPFSTADKRGG--GGT 71
|
90 100 110
....*....|....*....|....*....|....*..
gi 517596982 432 GLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPKT 467
Cdd:pfam02518 72 GLGLSIVRKLVELLGGTITVESEPGGgTTVTLTLPLA 108
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
233-465 |
1.73e-18 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 86.82 E-value: 1.73e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 233 EKTEIEKKQLEKSKQRMLVH----ISHDLKTPITTIQSYVEALQLGLIKEEARKQqaLHTIHTKARLVTELIEDVFELSK 308
Cdd:COG3852 118 ERKRLERELRRAEKLAAVGElaagLAHEIRNPLTGIRGAAQLLERELPDDELREY--TQLIIEEADRLNNLVDRLLSFSR 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 309 LESPDYpfptDTLDICEFIREIaaeyYSLFEE-----KQFNFQFE--IPFqkiyVLFNYTLLYRAVSNVLSNALKYNPEG 381
Cdd:COG3852 196 PRPPER----EPVNLHEVLERV----LELLRAeapknIRIVRDYDpsLPE----VLGDPDQLIQVLLNLVRNAAEAMPEG 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 382 TNILISliedTQKIHINIIDDGIGIPYA--------------VKEKVFEAFFrgdqSRKsDGGTGLGLTISKHIVEKHGG 447
Cdd:COG3852 264 GTITIR----TRVERQVTLGGLRPRLYVrievidngpgipeeILDRIFEPFF----TTK-EKGTGLGLAIVQKIVEQHGG 334
|
250
....*....|....*....
gi 517596982 448 QIYLHTDEGK-TRFQITLP 465
Cdd:COG3852 335 TIEVESEPGKgTTFRIYLP 353
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
230-465 |
7.01e-17 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 83.55 E-value: 7.01e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 230 EKLEKTEIEKKQLEKSkqrMLVHISHDLKTPITTIQSYVEALQLGLIKEEAR--------KQQALHTIhtkaRLVTELIE 301
Cdd:PRK10490 651 EEQARLASEREQLRNA---LLAALSHDLRTPLTVLFGQAEILTLDLASEGSPharqaseiRQQVLNTT----RLVNNLLD 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 302 dvfeLSKLESPDYPFPTDTLDICEFI----REIAaeyYSLfeeKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKY 377
Cdd:PRK10490 724 ----MARIQSGGFNLRKEWLTLEEVVgsalQMLE---PGL---SGHPINLSLPEPLTLIHVDGPLFERVLINLLENAVKY 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 378 NPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQsRKSDGGTGLGLTISKHIVEKHGGQIYLHT-DEG 456
Cdd:PRK10490 794 AGAQAEIGIDAHVEGERLQLDVWDNGPGIPPGQEQLIFDKFARGNK-ESAIPGVGLGLAICRAIVEVHGGTIWAENrPEG 872
|
....*....
gi 517596982 457 KTRFQITLP 465
Cdd:PRK10490 873 GACFRVTLP 881
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-466 |
2.65e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 74.28 E-value: 2.65e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEgtNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSD-GGTGLGLTISKHI 441
Cdd:cd16949 1 LARALENVLRNALRYSPS--KILLDISQDGDQWTITITDDGPGVPEDQLEQIFLPFYRVDSARDREsGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*.
gi 517596982 442 VEKHGGQIYL-HTDEGKTRFQITLPK 466
Cdd:cd16949 79 IEQHGGKIKAsNRKPGGLRVRIWLPA 104
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
182-467 |
5.16e-16 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 79.95 E-value: 5.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 182 WMAMKITN-PLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLekteiekKQLEKSKQRMLVHISHDLKTP 260
Cdd:PRK09467 171 WLFIRIQNrPLVALEHAALQVGKGEIPPPLREYGASEVRSVTRAFNQMAAGI-------KQLEDDRTLLMAGVSHDLRTP 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 261 ITTI----------QSYveaLQLGLIK--EE--ARKQQALHTIHTKARLVTELIedvfelsklespdypfptdtlDICEF 326
Cdd:PRK09467 244 LTRIrlatemmseeDGY---LAESINKdiEEcnAIIEQFIDYLRTGQEMPMEMA---------------------DLNAL 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 327 IRE-IAAE--YYSLFEEKQFNFQFEIPFQKIYVlfnytllYRAVSNVLSNALKYnpeGTN-ILISLIEDTQKIHINIIDD 402
Cdd:PRK09467 300 LGEvIAAEsgYEREIETALQPGPIEVPMNPIAI-------KRALANLVVNAARY---GNGwIKVSSGTEGKRAWFQVEDD 369
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517596982 403 GIGIPYAVKEKVFEAFFRGDQSRKSDgGTGLGLTISKHIVEKHGGQIYLHT-DEGKTRFQITLPKT 467
Cdd:PRK09467 370 GPGIPPEQLKHLFQPFTRGDSARGSS-GTGLGLAIVKRIVDQHNGKVELGNsEEGGLSARAWLPLT 434
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
359-451 |
4.01e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 71.34 E-value: 4.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 359 NYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSDGGTGLGLTIS 438
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDTSRRSGGHYGMGLYIA 80
|
90
....*....|...
gi 517596982 439 KHIVEKHGGQIYL 451
Cdd:cd16975 81 KNLVEKHGGSLII 93
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
367-465 |
4.56e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 70.98 E-value: 4.56e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 367 VSNVLSNALKYNPEGTNIL-ISLIEDTQKIHINIiddgigipYAVK-----------EKVFEAFFRGDQS--RKSdGGTG 432
Cdd:cd16922 5 LLNLLGNAIKFTEEGEVTLrVSLEEEEEDGVQLR--------FSVEdtgigipeeqqARLFEPFSQADSSttRKY-GGTG 75
|
90 100 110
....*....|....*....|....*....|....
gi 517596982 433 LGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:cd16922 76 LGLAISKKLVELMGGDISVESEPGQgSTFTFTLP 109
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
343-464 |
1.04e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 70.62 E-value: 1.04e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 343 FNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGD 422
Cdd:cd16947 1 FQVEINIPDRPIYANANTEALQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTLE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 517596982 423 QSR-KSDGGTGLGLTISKHIVEKHGGQIYLHTDEG-KTRFQITL 464
Cdd:cd16947 81 DSRnSAKQGNGLGLTITKRLAESMGGSIYVNSKPYeKTVFTVTL 124
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
354-464 |
1.71e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 69.36 E-value: 1.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 354 IYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAvKEKVFEAFFRGDQSrkSDGGTGL 433
Cdd:cd16940 5 IQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDGAVIRVEDNGPGIDEEE-LEALFERFYRSDGQ--NYGGSGL 81
|
90 100 110
....*....|....*....|....*....|.
gi 517596982 434 GLTISKHIVEKHGGQIYLHTDEGKtRFQITL 464
Cdd:cd16940 82 GLSIVKRIVELHGGQIFLGNAQGG-GLEAWV 111
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
365-465 |
1.07e-13 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 67.13 E-value: 1.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 365 RAVSNVLSNALKYNPEGTNILISL-IEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSR-KSDGGTGLGLTISKHIV 442
Cdd:cd16925 7 RVVLNLLSNAFKFTPDGGRIRCILeKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSStRAHGGTGLGLSIVKEFV 86
|
90 100
....*....|....*....|....
gi 517596982 443 EKHGGQIYLH-TDEGKTRFQITLP 465
Cdd:cd16925 87 ELHGGTVTVSdAPGGGALFQVELP 110
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
245-465 |
1.81e-13 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 73.23 E-value: 1.81e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 245 SKQRMLVHISHDLKTPITTIQSYVEALQ-LGLIKEEarKQQALHTIHTKARLVTELIEDVFELSKLESPDYPFPTDTLDI 323
Cdd:PRK09959 711 AKSQFLATMSHEIRTPISSIMGFLELLSgSGLSKEQ--RVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDI 788
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 324 CEFIREIAAEYYSLFEEKQFNFQFEIPFQKIYVL-FNYTLLYRAVSNVLSNALKYNPEG----TNILISLIEDTQKIHIN 398
Cdd:PRK09959 789 PTLVQNTCHSFGAIAASKSIALSCSSTFPDHYLVkIDPQAFKQVLSNLLSNALKFTTEGavkiTTSLGHIDDNHAVIKMT 868
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517596982 399 IIDDGIGIPYAVKEKVFEAFFRGDQSRKSDgGTGLGLTISKHIVEKHGGQIYLHTDEG-KTRFQITLP 465
Cdd:PRK09959 869 IMDSGSGLSQEEQQQLFKRYSQTSAGRQQT-GSGLGLMICKELIKNMQGDLSLESHPGiGTTFTITIP 935
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
245-312 |
2.15e-13 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 64.93 E-value: 2.15e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517596982 245 SKQRMLVHISHDLKTPITTIQSYVEALQLGLIKEEARkqQALHTIHTKARLVTELIEDVFELSKLESP 312
Cdd:pfam00512 1 AKSEFLANLSHELRTPLTAIRGYLELLRDEKLDEEQR--EYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
9.74e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 64.41 E-value: 9.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSR-KSDGGTGLGLTISKHI 441
Cdd:cd16946 5 LQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRnRASGGSGLGLAICHNI 84
|
90 100
....*....|....*....|....*
gi 517596982 442 VEKHGGQIYL-HTDEGKTRFQITLP 465
Cdd:cd16946 85 ALAHGGTISAeHSPLGGLRLVLTLP 109
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
1.43e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 63.76 E-value: 1.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSD-GGTGLGLTISKHI 441
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPPSDTITVRWSQEESGARLSVEDTGPGIPPEHIPRLTERFYRVDIERCRNtGGTGLGLAIVKHV 80
|
90 100
....*....|....*....|....*
gi 517596982 442 VEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:cd16952 81 MSRHDARLLIASELGKgSRFTCLFP 105
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
245-312 |
3.19e-12 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 61.43 E-value: 3.19e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517596982 245 SKQRMLVHISHDLKTPITTIQSYVEALQLGLIKEEarKQQALHTIHTKARLVTELIEDVFELSKLESP 312
Cdd:smart00388 1 AKREFLANLSHELRTPLTAIRGYLELLLDTELSEE--QREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
253-467 |
3.71e-12 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 67.69 E-value: 3.71e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 253 ISHDLKTPITTIQSYVEAL-QLG------LIkeeARKQQALHTIhtkarlvteliEDVFELSKLE----SPDYpfptDTL 321
Cdd:PRK10755 144 VAHELRTPLAGIRLHLELLeKQHhidvapLI---ARLDQMMHTV-----------EQLLQLARAGqsfsSGHY----QTV 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 322 DICE-FIREIAAEYYSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINII 400
Cdd:PRK10755 206 KLLEdVILPSQDELSEMLEQRQQTLLLPESAADITVQGDATLLRLLLRNLVENAHRYSPEGSTITIKLSQEDGGAVLAVE 285
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517596982 401 DDGIGIPYAVKEKVFEAFFRGDQSRksdGGTGLGLTISKHIVEKHGGQIYL--HTDEGKTRFQITLPKT 467
Cdd:PRK10755 286 DEGPGIDESKCGELSKAFVRMDSRY---GGIGLGLSIVSRITQLHHGQFFLqnRQERSGTRAWVWLPKA 351
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
238-466 |
4.52e-12 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 68.08 E-value: 4.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 238 EKKQLEKSKQR---------MLVHISHDLKTPITTIQSYVEALQlGLIKEEarKQQALHTIHTKARLVTELIEDVFELSK 308
Cdd:COG5809 253 ERKKLEELLRKseklsvvgeLAAGIAHEIRNPLTSLKGFIQLLK-DTIDEE--QKTYLDIMLSELDRIESIISEFLVLAK 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 309 LESPDYpfptDTLDICEFIREIAaeyySLFE----EKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNI 384
Cdd:COG5809 330 PQAIKY----EPKDLNTLIEEVI----PLLQpqalLKNVQIELELEDDIPDILGDENQLKQVFINLLKNAIEAMPEGGNI 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 385 LISL-IEDTQKIHINIIDDGIGIPYAVKEKVFEAFFrgdqSRKsDGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQI 462
Cdd:COG5809 402 TIETkAEDDDKVVISVTDEGCGIPEERLKKLGEPFY----TTK-EKGTGLGLMVSYKIIEEHGGKITVESEVGKgTTFSI 476
|
....
gi 517596982 463 TLPK 466
Cdd:COG5809 477 TLPI 480
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
4.58e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 62.34 E-value: 4.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEGtnilislieDTQKIHINIIDDGIGIPYAVK-----------EKVFEAFFRGDqSRKSDGGT 431
Cdd:cd16921 1 LGQVLTNLLGNAIKFRRPR---------RPPRIEVGAEDVGEEWTFYVRdngigidpeyaEKVFGIFQRLH-SREEYEGT 70
|
90 100 110
....*....|....*....|....*....|....*
gi 517596982 432 GLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:cd16921 71 GVGLAIVRKIIERHGGRIWLESEPGEgTTFYFTLP 105
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
243-308 |
5.69e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 60.69 E-value: 5.69e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517596982 243 EKSKQRMLVHISHDLKTPITTIQSYVEALQLGLIKEEaRKQQALHTIHTKARLVTELIEDVFELSK 308
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEEELLDDE-EQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
7.25e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 61.68 E-value: 7.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYnpEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSR-KSDGGTGLGLTISKHI 441
Cdd:cd16939 1 MARALDNLLRNALRY--AHRTVRIALLVSGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPSRdRATGGFGLGLAIVHRV 78
|
90 100
....*....|....*....|....*
gi 517596982 442 VEKHGGQIYLHTDE-GKTRFQITLP 465
Cdd:cd16939 79 ALWHGGHVECDDSElGGACFRLTWP 103
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
238-465 |
1.66e-11 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 66.50 E-value: 1.66e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 238 EKKQ----LEKS---KQRMLVHISHDLKTPITTIQsyveALQLGLIKEEARKQQA--LHTIHTKARLVTELIEDVFELSK 308
Cdd:PRK11091 268 ERKRyqdaLEKAsrdKTTFISTISHELRTPLNGIV----GLSRILLDTELTAEQRkyLKTIHVSAITLGNIFNDIIDMDK 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 309 LESPDYPFPTDTLDICEFIREIAAEYYSLFEEKQFNFQFEI--PFqKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILI 386
Cdd:PRK11091 344 MERRKLQLDNQPIDFTDFLADLENLSGLQAEQKGLRFDLEPllPL-PHKVITDGTRLRQILWNLISNAVKFTQQGGVTVR 422
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 387 SLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSR--KSDGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQIT 463
Cdd:PRK11091 423 VRYEEGDMLTFEVEDSGIGIPEDELDKIFAMYYQVKDSHggKPATGTGIGLAVSKRLAQAMGGDITVTSEEGKgSCFTLT 502
|
..
gi 517596982 464 LP 465
Cdd:PRK11091 503 IH 504
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
362-451 |
3.54e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 59.78 E-value: 3.54e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 362 LLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFF---RGDQSRKSdggTGLGLTIS 438
Cdd:cd16945 4 LLRQAINNLLDNAIDFSPEGGLIALQLEADTEGIELLVFDEGSGIPDYALNRVFERFYslpRPHSGQKS---TGLGLAFV 80
|
90
....*....|...
gi 517596982 439 KHIVEKHGGQIYL 451
Cdd:cd16945 81 QEVAQLHGGRITL 93
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
255-456 |
1.01e-10 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 63.51 E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 255 HDLKTPITTIQSYVEALQLGLIKEEARkQQALHTIHTKARLVTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEY 334
Cdd:PRK10337 246 HELRSPLAALKVQTEVAQLSDDDPQAR-KKALLQLHAGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSAVMDI 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 335 YSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIhinIIDDGIGIPYAVkEKV 414
Cdd:PRK10337 325 YHTAQQAGIDVRLTLNAHPVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNARNFTV---RDNGPGVTPEAL-ARI 400
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 517596982 415 FEAFFRGDQSRKSdgGTGLGLTISKHIVEKHGGQIYL-HTDEG 456
Cdd:PRK10337 401 GERFYRPPGQEAT--GSGLGLSIVRRIAKLHGMNVSFgNAPEG 441
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
253-465 |
1.36e-10 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 63.45 E-value: 1.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 253 ISHDLKTPITTIQSYVEALQLGLIKEEARKqqALHTIHTKARLVTELIEDVFELSKlESPDYPFPtdtLDICEFIREIAa 332
Cdd:PRK11360 397 VAHEIRNPLTAIRGYVQIWRQQTSDPPSQE--YLSVVLREVDRLNKVIDQLLEFSR-PRESQWQP---VSLNALVEEVL- 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 333 eyySLFEE--KQFNFQFEIPFQ----KIYVlfNYTLLYRAVSNVLSNALKYNPEGTNILIS--LIEDTQkIHINIIDDGI 404
Cdd:PRK11360 470 ---QLFQTagVQARVDFETELDnelpPIWA--DPELLKQVLLNILINAVQAISARGKIRIRtwQYSDGQ-VAVSIEDNGC 543
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517596982 405 GIPYAVKEKVFEAFFRGDQSrksdgGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:PRK11360 544 GIDPELLKKIFDPFFTTKAK-----GTGLGLALSQRIINAHGGDIEVESEPGVgTTFTLYLP 600
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
1.66e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 58.07 E-value: 1.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRGDQSRKSDGGTGLGLTISKHIV 442
Cdd:cd16948 6 LSFIIGQIVSNALKYSKQGGKIEIYSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENGRNFQESTGMGLYLVKKLC 85
|
90 100
....*....|....*....|....
gi 517596982 443 EKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:cd16948 86 DKLGHKIDVESEVGEgTTFTITFP 109
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-456 |
2.27e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 57.46 E-value: 2.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKY---------NPEGTNILISLIEDTQKIhiniiddgigIPYAVKEkVFEAFFRGDQSRKSdGGTGL 433
Cdd:cd16950 1 LKRVLSNLVDNALRYgggwvevssDGEGNRTRIQVLDNGPGI----------APEEVDE-LFQPFYRGDNARGT-SGTGL 68
|
90 100
....*....|....*....|...
gi 517596982 434 GLTISKHIVEKHGGQIYLHTDEG 456
Cdd:cd16950 69 GLAIVQRISDAHGGSLTLANRAG 91
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
233-468 |
3.54e-10 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 61.79 E-value: 3.54e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 233 EKTEIE--KKQLEKSKQ--RMLVHISHDLKTPITTIQSYveaLQLGlikeeaRKQQALHTIHTKARLVTELIEdvFELSK 308
Cdd:COG3290 172 DRTELErlEEELEGVKElaEALRAQRHDFRNHLHTISGL---LQLG------EYDEALEYIDEISEELQELID--SLLSR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 309 LESPDypfptdtldicefIREIAAEYYSLFEEKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNAL----KYNPEGTNI 384
Cdd:COG3290 241 IGNPV-------------LAALLLGKAARARERGIDLTIDIDSDLPDLPLSDTDLVTILGNLLDNAIeaveKLPEEERRV 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 385 LISLIEDTQKIHINIIDDGIGIPYAVKEKVFEaffRGDQSrKSDGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQIT 463
Cdd:COG3290 308 ELSIRDDGDELVIEVEDSGPGIPEELLEKIFE---RGFST-KLGEGRGLGLALVKQIVEKYGGTIEVESEEGEgTVFTVR 383
|
....*
gi 517596982 464 LPKTG 468
Cdd:COG3290 384 LPKEG 388
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
407-465 |
6.36e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 53.55 E-value: 6.36e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 407 PYAVKEKVFEAFFrgdqSRKSDGgTGLGLTISKHIVEKHGGQI-YLHTDEGKTRFQITLP 465
Cdd:cd16920 50 AEEVAGQLFDPFY----TTKSEG-LGMGLSICRSIIEAHGGRLsVESPAGGGATFQFTLP 104
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
410-465 |
6.92e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 53.19 E-value: 6.92e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 517596982 410 VKEKVFEAFFrgdQSRKSDGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:cd16943 51 ILGRIFDPFF---TTKPVGEGTGLGLSLSYRIIQKHGGTIRVASVPGGgTRFTIILP 104
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
253-467 |
8.63e-09 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 57.43 E-value: 8.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 253 ISHDLKTPITTIQSYVEALQLGLIKEEARKQQALHTIHTKARLVTELIedvfELSKLESPDYpfptDTLDICEFIREIAA 332
Cdd:COG5805 294 IAHEIRNPLTSIKGFLQLLQPGIEDKEEYFDIMLSELDRIESIISEFL----ALAKPQAVNK----EKENINELIQDVVT 365
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 333 --EYYSLFEEKQFNFQFEIPFQKIYVLFNYtlLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAV 410
Cdd:COG5805 366 llETEAILHNIQIRLELLDEDPFIYCDENQ--IKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEER 443
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 517596982 411 KEKVFEAFFrgdqSRKsDGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPKT 467
Cdd:COG5805 444 LKKLGEPFF----TTK-EKGTGLGLMVSYKIIENHNGTIDIDSKVGKgTTFTITLPLS 496
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
230-465 |
1.03e-08 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 57.94 E-value: 1.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 230 EKLEKTEIEKKQLEKSKQR----------MLVHISHDLKTPIT-----TIQsyvealqlgLIKEEARKQQA--LHTIHTK 292
Cdd:PRK11107 267 ETLEQMEIQNVELDLAKKRaqeaarikseFLANMSHELRTPLNgvigfTRQ---------TLKTPLTPTQRdyLQTIERS 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 293 ARLVTELIEDVFELSKLES-----PDYPFP-TDTLDicEFIREIA--AEyyslfeEKQF----NFQFEIP---------F 351
Cdd:PRK11107 338 ANNLLAIINDILDFSKLEAgklvlENIPFSlRETLD--EVVTLLAhsAH------EKGLeltlNIDPDVPdnvigdplrL 409
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 352 QKIyvlfnytllyraVSNVLSNALKYNPEGtNILISL----IEDTQ-KIHINIIDDGIGIPYAVKEKVFEAFFRGDQS-- 424
Cdd:PRK11107 410 QQI------------ITNLVGNAIKFTESG-NIDILVelraLSNTKvQLEVQIRDTGIGISERQQSQLFQAFRQADASis 476
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 517596982 425 RKSdGGTGLGLTISKHIVEKHGGQIYLHT--DEGKTrFQITLP 465
Cdd:PRK11107 477 RRH-GGTGLGLVITQKLVNEMGGDISFHSqpNRGST-FWFHLP 517
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
208-470 |
2.04e-08 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 56.96 E-value: 2.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 208 KRLRFKSNYELMQIQNDFNLM---------------AEKLEKTEIEKKQLEKSKQRMLVH---ISHDLKTPITTIQSYVE 269
Cdd:PRK15347 342 PRLPENRLDELGSIAKAYNQLldtlneqydtlenkvAERTQALAEAKQRAEQANKRKSEHlttISHEIRTPLNGVLGALE 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 270 ALQLGLIkeEARKQQALHTIHTKARLVTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEYYSLFEEKQFNFQF-- 347
Cdd:PRK15347 422 LLQNTPL--TAEQMDLADTARQCTLSLLAIINNLLDFSRIESGQMTLSLEETALLPLLDQAMLTIQGPAQSKSLTLRTfv 499
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 348 --EIPfqkIYVLFNYTLLYRAVSNVLSNALKYNPEG---------TNILISLIEDT------QKIhiniiddgigipyav 410
Cdd:PRK15347 500 gaHVP---LYLHLDSLRLRQILVNLLGNAVKFTETGgirlrvkrhEQQLCFTVEDTgcgidiQQQ--------------- 561
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517596982 411 kEKVFEAFFrgdQSRKSDGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLPKTGYN 470
Cdd:PRK15347 562 -QQIFTPFY---QADTHSQGTGLGLTIASSLAKMMGGELTLFSTPGVgSCFSLVLPLNEYA 618
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
180-311 |
2.63e-08 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 56.27 E-value: 2.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 180 SRWMAMKITNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLEKTEIEKKQLEKSKQRMLVHISHDLKT 259
Cdd:COG2770 229 ALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLE 308
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 517596982 260 PITTIQSYVEALQLGLIKEEARKQQALHTIHTKARLVTELIEDVFELSKLES 311
Cdd:COG2770 309 LLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALL 360
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
407-465 |
1.73e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 49.69 E-value: 1.73e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517596982 407 PYAVKEKVFEAFFrgdqSRKSDG-GTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:cd16919 60 PAEVLRRAFEPFF----TTKEVGkGTGLGLSMVYGFVKQSGGHLRIYSEPGVgTTVRIYLP 116
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
363-465 |
2.26e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 49.11 E-value: 2.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 363 LYRAVSNVLSNALKYNPEGT-NILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFRgDQSRKSDGGT--GLGLTISK 439
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDTgRITVSAMPTGKMVTISVEDEGPGIPQEKLESIFDRFYT-ERPANEAFGQhsGLGLSISR 79
|
90 100 110
....*....|....*....|....*....|.
gi 517596982 440 HIVEKHGGQIY--LHTDEGK---TRFQITLP 465
Cdd:cd16953 80 QIIEAHGGISVaeNHNQPGQvigARFTVQLP 110
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
180-464 |
4.25e-07 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 52.19 E-value: 4.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 180 SRWMAMKITNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLEKTEiekKQLEKSKQRMLVHISHDLKT 259
Cdd:COG3850 135 AYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELY---AELEEEEELEAELELLALLD 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 260 PITTIQSYVEALQLGLIKEEARKQQALHTIHTKARLVTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAEYYSLFE 339
Cdd:COG3850 212 ELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASALLLLELELLALLLE 291
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 340 EKQFNFQFEIPFQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKV---FE 416
Cdd:COG3850 292 LVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEAAAAGAALAAAAaaaGL 371
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 517596982 417 AFFRGDQSRKSDGGTGLGLTISKHIVEKHGGQIYLHTDEGKTRFQITL 464
Cdd:COG3850 372 ARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGGVAGEGGLVVL 419
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
407-465 |
5.62e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 48.17 E-value: 5.62e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 517596982 407 PYAVKEKVFEAFFRGdqsrkSDGGTGLGLTISKHIVEKHGGQIYLHTDEGKTRFQITLP 465
Cdd:cd16918 56 PPDLQDTIFYPMVSG-----RENGTGLGLAIAQNIVSQHGGVIECDSQPGHTVFSVSLP 109
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
218-333 |
2.11e-06 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 50.32 E-value: 2.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 218 LMQIQNDFNLMAEKLEKT--EIEKKQleKSKQRMLVHISHDLKTPITTIQSyvEALQLGLIKEEARKQQALHTIHTKARL 295
Cdd:PRK10618 422 LLRDQDREVLVNKKLQQAqrEYEKNQ--QARKAFLQNIGDELKQPLQSLAQ--LAAQLRQTSDEEQQQPELDQLAEQSDV 497
|
90 100 110
....*....|....*....|....*....|....*...
gi 517596982 296 VTELIEDVFELSKLESPDYPFPTDTLDICEFIREIAAE 333
Cdd:PRK10618 498 LVRLVDNIQLLNMLETQDWKPEQELFSLQDLIDEVLPE 535
|
|
| HAMP |
pfam00672 |
HAMP domain; |
182-234 |
3.46e-06 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 44.15 E-value: 3.46e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 517596982 182 WMAMKITNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLEK 234
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
337-464 |
7.89e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 45.32 E-value: 7.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 337 LFEEKQFNFQFEIPfQKIYVLFNYTLLYRAVSNVLSNALKYNPEgtNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFE 416
Cdd:cd16954 13 VYQRKGVSISLDIS-PELRFPGERNDLMELLGNLLDNACKWCLE--FVEVTARQTDGGLHLIVDDDGPGVPESQRSKIFQ 89
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 517596982 417 AFFRGDQSRKsdgGTGLGLTISKHIVEKHGGQIYL-HTDEGKTRFQITL 464
Cdd:cd16954 90 RGQRLDEQRP---GQGLGLAIAKEIVEQYGGELSLsDSPLGGARFEVVF 135
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
367-465 |
1.70e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 43.43 E-value: 1.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 367 VSNVLSNAL----KYNPEGTNILISLIEDTQKIHINIIDDGIGIPYAVKEKVFEAFFrgdqSRKSDGGTGLGLTISKHIV 442
Cdd:cd16915 5 VGNLIDNALdalaATGAPNKQVEVFLRDEGDDLVIEVRDTGPGIAPELRDKVFERGV----STKGQGERGIGLALVRQSV 80
|
90 100
....*....|....*....|....
gi 517596982 443 EKHGGQIYL-HTDEGKTRFQITLP 465
Cdd:cd16915 81 ERLGGSITVeSEPGGGTTFSIRIP 104
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
367-465 |
1.84e-05 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 47.21 E-value: 1.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 367 VSNVLSNALKYNPEGTNILISLIEDTQKIHINIIDDGIGIPyAVKEKVFEAFFRGDQSRksdGGTGLGLTISKHIVEKHG 446
Cdd:PRK11466 566 ITNLLSNALRFTDEGSIVLRSRTDGEQWLVEVEDSGCGIDP-AKLAEIFQPFVQVSGKR---GGTGLGLTISSRLAQAMG 641
|
90 100
....*....|....*....|
gi 517596982 447 GQIYLHTDEGK-TRFQITLP 465
Cdd:PRK11466 642 GELSATSTPEVgSCFCLRLP 661
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
230-451 |
3.32e-05 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 46.22 E-value: 3.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 230 EKLEKTEIEKKQLEK---SKQRMlVHISHDLKTPITTIQSYVEALQLGLIKEEArkQQALHTIHTKARLVTELIEDVFEL 306
Cdd:COG4192 415 KNLRQTQDELIQAAKmavVGQTM-TSLAHELNQPLNAMSMYLFSAKKALEQENY--AQLPTSLDKIEGLIERMDKIIKSL 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 307 ----SKLESPDYPFPtdtldicefIREIAAEYYSLFE--EKQFNFQFEIPfQKIYVLFNYTLLYRAVSNVLSNALKYNPE 380
Cdd:COG4192 492 rqfsRKSDTPLQPVD---------LRQVIEQAWELVEsrAKPQQITLHIP-DDLMVQGDQVLLEQVLVNLLVNALDAVAT 561
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517596982 381 GTNILISLIEDTQKIHINIIDDGIGIPYAvkEKVFEAFFrgdqSRKsDGGTGLGLTISKHIVEKHGGQIYL 451
Cdd:COG4192 562 QPQISVDLLSNAENLRVAISDNGNGWPLV--DKLFTPFT----TTK-EVGLGLGLSICRSIMQQFGGDLYL 625
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
428-465 |
4.43e-05 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 45.46 E-value: 4.43e-05
10 20 30
....*....|....*....|....*....|....*...
gi 517596982 428 DGGTGLGLTISKHIVEKHGGQIYLHTDEGKTRFQITLP 465
Cdd:PRK11073 309 EGGTGLGLSIARNLIDQHSGKIEFTSWPGHTEFSVYLP 346
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
412-465 |
4.89e-05 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 45.55 E-value: 4.89e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 517596982 412 EKVFEAFFrgdqSRKSDGgTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:PRK10364 398 EAIFTPYF----TTKAEG-TGLGLAVVHNIVEQHGGTIQVASQEGKgATFTLWLP 447
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
188-232 |
5.08e-05 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 40.51 E-value: 5.08e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 517596982 188 TNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKL 232
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
407-456 |
6.28e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 42.06 E-value: 6.28e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 517596982 407 PYAVKEKVFEAFFrgdqSRKSDG-GTGLGLTISKHIVEKHGGQIYLHTDEG 456
Cdd:cd16976 47 AEEHLSRVFDPFF----TTKPVGkGTGLGLSISYGIVEEHGGRLSVANEEG 93
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
187-236 |
9.81e-05 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 39.92 E-value: 9.81e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 517596982 187 ITNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLEKTE 236
Cdd:smart00304 3 LLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETI 52
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
228-465 |
9.94e-05 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 44.96 E-value: 9.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 228 MAEKLEKTEIEKKQLEKSKQRMLVHISHDLKTPITTIQSYVEALQLGLIKEEArkQQALHTIHTKARLVTELIEDVFELS 307
Cdd:PRK10841 429 MEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGV--DRLVTAMNNSSSLLLKIISDILDFS 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 308 KLESpdypfptDTLDI--CEF-----IREIAAEYYSLFEEKQFNFQFEI-PFQKIYVLFNYTLLYRAVSNVLSNALKYNP 379
Cdd:PRK10841 507 KIES-------EQLKIepREFsprevINHITANYLPLVVKKRLGLYCFIePDVPVALNGDPMRLQQVISNLLSNAIKFTD 579
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 380 EGTNIL----------ISlIEDTqkihiniiddgigipyAV----KE--KVFEAFFR-GDQSRKSDGGTGLGLTISKHIV 442
Cdd:PRK10841 580 TGCIVLhvrvdgdylsFR-VRDT----------------GVgipaKEvvRLFDPFFQvGTGVQRNFQGTGLGLAICEKLI 642
|
250 260
....*....|....*....|....
gi 517596982 443 EKHGGQIYLHTDEG-KTRFQITLP 465
Cdd:PRK10841 643 NMMDGDISVDSEPGmGSQFTIRIP 666
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
430-465 |
1.79e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 40.98 E-value: 1.79e-04
10 20 30
....*....|....*....|....*....|....*..
gi 517596982 430 GTGLGLTISKHIVEKHGGQIYL-HTDEGKTRFQITLP 465
Cdd:cd16944 72 GTGLGLAIVKKIMEEHGGRISLsNREAGGACIRIILP 108
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
253-465 |
2.79e-04 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 43.51 E-value: 2.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 253 ISHDLKTPITTIQSYVEALQLGLIKEEARKQQALHTIHTKARlVTELIEDVFELS-KLESPDYPFptdtlDICEFIREIA 331
Cdd:PRK13837 457 IAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIISAGAR-ARLIIDQILAFGrKGERNTKPF-----DLSELVTEIA 530
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 332 AEY-YSLFEEKQFNFQFEIpfQKIYVLFNYTLLYRAVSNVLSNALKYNPEGTNILISLieDTQKIHINIIDDGIGIP--- 407
Cdd:PRK13837 531 PLLrVSLPPGVELDFDQDQ--EPAVVEGNPAELQQVLMNLCSNAAQAMDGAGRVDISL--SRAKLRAPKVLSHGVLPpgr 606
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517596982 408 Y--------------AVKEKVFEAFFrgdQSRKsdGGTGLGLTISKHIVEKHGGQIYLHTDEGK-TRFQITLP 465
Cdd:PRK13837 607 YvllrvsdtgagideAVLPHIFEPFF---TTRA--GGTGLGLATVHGIVSAHAGYIDVQSTVGRgTRFDVYLP 674
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
209-470 |
1.03e-03 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 41.43 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 209 RLRFKSNYELMQIQNDFNLMAEKLEKTEIEKKQLEKSKQRMLVHISHDLKTPITTIQSYVeALQLGLIKEEARKQ----- 283
Cdd:COG3920 258 LLLLLLLRALLLLAAGIRLVITERKRAEEELEASLEEKELLLRELHHRVKNNLQVVSSLL-RLQARRADDPEAREalees 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 284 ----QALHTIHTKarlvteliedvfeLSklESPDYpfptDTLDICEFIREIAAEYYSLFEEKQFNFQFEIPFqkiyVLFN 359
Cdd:COG3920 337 qnriQALALVHEL-------------LY--QSEDW----EGVDLRDYLRELLEPLRDSYGGRGIRIELDGPD----VELP 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517596982 360 ytlLYRAVS-----N-VLSNALKY----NPEGTnILISLIEDTQKIHINIIDDGIGIPYAVKEkvfeaffrgdqsrksDG 429
Cdd:COG3920 394 ---ADAAVPlglilNeLVTNALKHaflsGEGGR-IRVSWRREDGRLRLTVSDNGVGLPEDVDP---------------PA 454
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 517596982 430 GTGLGLTISKHIVEKHGGQIYLHTDEGkTRFQITLPKTGYN 470
Cdd:COG3920 455 RKGLGLRLIRALVRQLGGTLELDRPEG-TRVRITFPLAELA 494
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
178-235 |
8.60e-03 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 38.46 E-value: 8.60e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 517596982 178 IYSRWMAMKITNPLRSIADGIRNITNGYYYKRLRFKSNYELMQIQNDFNLMAEKLEKT 235
Cdd:COG0840 197 ILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLREL 254
|
|
| |
