|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08638 |
PRK08638 |
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB; |
1-330 |
0e+00 |
|
bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB;
Pssm-ID: 236317 [Multi-domain] Cd Length: 333 Bit Score: 532.00 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 1 MINKNLPLNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIAC 80
Cdd:PRK08638 2 HITYDLPVAIDDIIEAKQRLAGRIRKTPLPRSNYLSERCKGEIFLKLENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVAC 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 81 SAGNHAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAG 160
Cdd:PRK08638 82 SAGNHAQGVALSCALLGIDGKVVMPKGAPKSKVAATCGYGAEVVLHGDNFNDTIAKVEEIVEEEGRTFIPPYDDPKVIAG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 161 QGTIGLDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVK 240
Cdd:PRK08638 162 QGTIGLEILEDLWDVDTVIVPIGGGGLIAGIAVALKSINPTIHIIGVQSENVHGMAASFYAGEITTHRTTGTLADGCDVS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 241 IPGDLTFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISGGNVDLKRIS 320
Cdd:PRK08638 242 RPGNLTYEIVRELVDDIVLVSEDEIRNAMKDLIQRNKVVTEGAGALATAALLSGKLDQYIQNKKVVAIISGGNVDLSRVS 321
|
330
....*....|
gi 517597650 321 SVCEHFFVAN 330
Cdd:PRK08638 322 QITGHVVAAD 331
|
|
| Thr-dehyd |
cd01562 |
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. ... |
10-315 |
1.04e-142 |
|
Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly converted into NH4+. The direct deamination is catalyzed by threonine dehydratase, in which pyridoxal phosphate (PLP) is the prosthetic group. Threonine dehydratase is widely distributed in all three major phylogenetic divisions.
Pssm-ID: 107205 [Multi-domain] Cd Length: 304 Bit Score: 405.33 E-value: 1.04e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 10 IGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGV 89
Cdd:cd01562 1 LEDILAAAARIKPVVRRTPLLTSPTLSELLGAEVYLKCENLQKTGSFKIRGAYNKLLSLSEEERAKGVVAASAGNHAQGV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 90 ALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDIL 169
Cdd:cd01562 81 AYAAKLLGIPATIVMPETAPAAKVDATRAYGAEVVLYGEDFDEAEAKARELAEEEGLTFIHPFDDPDVIAGQGTIGLEIL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 170 DDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDLTFEI 249
Cdd:cd01562 161 EQVPDLDAVFVPVGGGGLIAGIATAVKALSPNTKVIGVEPEGAPAMAQSLAAGKPVTLPEVDTIADGLAVKRPGELTFEI 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517597650 250 VKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQytKGKKVVAVISGGNVD 315
Cdd:cd01562 241 IRKLVDDVVTVSEDEIAAAMLLLFEREKLVAEPAGALALAALLSGKLDL--KGKKVVVVLSGGNID 304
|
|
| IlvA |
COG1171 |
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the ... |
6-329 |
7.66e-134 |
|
Threonine deaminase [Amino acid transport and metabolism]; Threonine deaminase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440784 [Multi-domain] Cd Length: 327 Bit Score: 383.62 E-value: 7.66e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 6 LPLNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNH 85
Cdd:COG1171 4 LMPTLADIEAAAARIAGVVRRTPLLRSPTLSERLGAEVYLKLENLQPTGSFKLRGAYNALASLSEEERARGVVAASAGNH 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 86 AQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIG 165
Cdd:COG1171 84 AQGVAYAARLLGIPATIVMPETAPAVKVAATRAYGAEVVLHGDTYDDAEAAAAELAEEEGATFVHPFDDPDVIAGQGTIA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 166 LDILDDMWDVDTVivpiggggiisgiAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDL 245
Cdd:COG1171 164 LEILEQLPDLDAVfvpvggggliagvAAALKALSPDIRVIGVEPEGAAAMYRSLAAGEPVTLPGVDTIADGLAVGRPGEL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 246 TFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVE----------GAGALATaallagkvdqytKGKKVVAVISGGNVD 315
Cdd:COG1171 244 TFEILRDLVDDIVTVSEDEIAAAMRLLLERTKIVVEpagaaalaalLAGKERL------------KGKRVVVVLSGGNID 311
|
330
....*....|....
gi 517597650 316 LKRISSVCEHFFVA 329
Cdd:COG1171 312 PDRLAEILERGLVG 325
|
|
| ilvA_1Cterm |
TIGR01127 |
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the ... |
27-322 |
1.34e-112 |
|
threonine ammonia-lyase, medium form; A form of threonine dehydratase with two copies of the C-terminal domain pfam00585 is described by TIGR01124. This model describes a phylogenetically distinct form with a single copy of pfam00585. This form branches with the catabolic threonine dehydratase of E. coli; many members are designated as catabolic for this reason. However, the catabolic form lacks any pfam00585 domain. Many members of this model are found in species with other Ile biosynthetic enzymes. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130197 [Multi-domain] Cd Length: 380 Bit Score: 331.71 E-value: 1.34e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGVALSSHLLGIKSKIVMPI 106
Cdd:TIGR01127 1 TPLIYSTTLSDITGSEVYLKLENLQKTGSFKIRGALNKIANLSEDQRQRGVVAASAGNHAQGVAYAAKKFGIKAVIVMPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 107 SAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDILDDMWDVDTVIVPIGGGG 186
Cdd:TIGR01127 81 SAPPSKVKATKSYGAEVILHGDDYDEAYAFATSLAEEEGRVFVHPFDDEFVMAGQGTIGLEIMEDIPDVDTVIVPVGGGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 187 IISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDLTFEIVKELVDDIVTVSEEELE 266
Cdd:TIGR01127 161 LISGVASAAKQINPNVKVIGVEAEGAPSMYESLREGKIKAVESVRTIADGIAVKKPGDLTFNIIKEYVDDVVTVDEEEIA 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 517597650 267 VAMKDLLQRGKAVVEGAGALATAALLAGKVDQytKGKKVVAVISGGNVDLKRISSV 322
Cdd:TIGR01127 241 NAIYLLLERHKILAEGAGAAGVAALLEQKVDV--KGKKIAVVLSGGNIDLNLLNKI 294
|
|
| PRK07334 |
PRK07334 |
threonine dehydratase; Provisional |
6-324 |
1.11e-96 |
|
threonine dehydratase; Provisional
Pssm-ID: 235994 [Multi-domain] Cd Length: 403 Bit Score: 291.80 E-value: 1.11e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 6 LPLNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNH 85
Cdd:PRK07334 3 LMVTLADIRAAAARLAGQVLRTPCVHSRTLSQITGAEVWLKFENLQFTASFKERGALNKLLLLTEEERARGVIAMSAGNH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 86 AQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIG 165
Cdd:PRK07334 83 AQGVAYHAQRLGIPATIVMPRFTPTVKVERTRGFGAEVVLHGETLDEARAHARELAEEEGLTFVHPYDDPAVIAGQGTVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 166 LDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASydvgkiVSHYEAP----TIADGCAVKI 241
Cdd:PRK07334 163 LEMLEDAPDLDTLVVPIGGGGLISGMATAAKALKPDIEIIGVQTELYPSMYAA------IKGVALPcggsTIAEGIAVKQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 242 PGDLTFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKvdQYTKGKKVVAVISGGNVDLKRISS 321
Cdd:PRK07334 237 PGQLTLEIVRRLVDDILLVSEADIEQAVSLLLEIEKTVVEGAGAAGLAALLAYP--ERFRGRKVGLVLSGGNIDTRLLAN 314
|
...
gi 517597650 322 VCE 324
Cdd:PRK07334 315 VLL 317
|
|
| PRK09224 |
PRK09224 |
threonine ammonia-lyase IlvA; |
24-324 |
5.11e-91 |
|
threonine ammonia-lyase IlvA;
Pssm-ID: 236417 [Multi-domain] Cd Length: 504 Bit Score: 280.49 E-value: 5.11e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 24 ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGVALSSHLLGIKSKIV 103
Cdd:PRK09224 18 AQETPLEKAPKLSARLGNQVLLKREDLQPVFSFKLRGAYNKMAQLTEEQLARGVITASAGNHAQGVALSAARLGIKAVIV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 104 MPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDILDDMWD-VDTVIVPI 182
Cdd:PRK09224 98 MPVTTPDIKVDAVRAFGGEVVLHGDSFDEAYAHAIELAEEEGLTFIHPFDDPDVIAGQGTIAMEILQQHPHpLDAVFVPV 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 183 GGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDLTFEIVKELVDDIVTVSE 262
Cdd:PRK09224 178 GGGGLIAGVAAYIKQLRPEIKVIGVEPEDSACLKAALEAGERVDLPQVGLFADGVAVKRIGEETFRLCQEYVDDVITVDT 257
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517597650 263 EELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISGGNVDLKRISSVCE 324
Cdd:PRK09224 258 DEICAAIKDVFEDTRSIAEPAGALALAGLKKYVAQHGIEGETLVAILSGANMNFDRLRYVAE 319
|
|
| ilvA_2Cterm |
TIGR01124 |
threonine ammonia-lyase, biosynthetic, long form; This model describes a form of threonine ... |
24-324 |
7.42e-91 |
|
threonine ammonia-lyase, biosynthetic, long form; This model describes a form of threonine ammonia-lyase, a pyridoxal-phosphate dependent enzyme, with two copies of the threonine dehydratase C-terminal domain (pfam00585). Members with known function participate in isoleucine biosynthesis and are inhibited by isoleucine. Alternate name: threonine deaminase, threonine dehydratase. Forms scoring between the trusted and noise cutoff tend to branch with this subgroup of threonine ammonia-lyase phylogenetically but have only a single copy of the C-terminal domain. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130194 [Multi-domain] Cd Length: 499 Bit Score: 280.08 E-value: 7.42e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 24 ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGVALSSHLLGIKSKIV 103
Cdd:TIGR01124 15 AQETPLQKAAKLSERLGNRILIKREDLQPVFSFKLRGAYNKMAQLSPEQKARGVIAASAGNHAQGVAFSAARLGLKALIV 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 104 MPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDIL-DDMWDVDTVIVPI 182
Cdd:TIGR01124 95 MPETTPDIKVDAVRGFGGEVVLHGANFDDAKAKAIELSQEKGLTFIHPFDDPLVIAGQGTLALEILrQVANPLDAVFVPV 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 183 GGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDLTFEIVKELVDDIVTVSE 262
Cdd:TIGR01124 175 GGGGLAAGVAALIKQLMPEIKVIGVEPTDSDCMKQALDAGEPVDLDQVGLFADGVAVKRVGDETFRLCQQYLDDIVTVDT 254
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517597650 263 EELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISGGNVDLKRISSVCE 324
Cdd:TIGR01124 255 DEVCAAIKDLFEDTRAVAEPAGALALAGLKKYVALHGIRGQTLVAILSGANMNFHRLRYVSE 316
|
|
| PRK07048 |
PRK07048 |
threo-3-hydroxy-L-aspartate ammonia-lyase; |
6-321 |
3.25e-86 |
|
threo-3-hydroxy-L-aspartate ammonia-lyase;
Pssm-ID: 235918 [Multi-domain] Cd Length: 321 Bit Score: 262.26 E-value: 3.25e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 6 LPLNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNH 85
Cdd:PRK07048 4 LLPTYDDVAAAAARLAGVAHRTPVLTSRTADARTGAQVFFKCENFQRMGAFKFRGAYNALSQFSPEQRRAGVVTFSSGNH 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 86 AQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIG 165
Cdd:PRK07048 84 AQAIALSARLLGIPATIVMPQDAPAAKVAATRGYGGEVVTYDRYTEDREEIGRRLAEERGLTLIPPYDHPHVIAGQGTAA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 166 LDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVsHYEAP-TIADGCAVKIPGD 244
Cdd:PRK07048 164 KELFEEVGPLDALFVCLGGGGLLSGCALAARALSPGCKVYGVEPEAGNDGQQSFRSGEIV-HIDTPrTIADGAQTQHLGN 242
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517597650 245 LTFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDqyTKGKKVVAVISGGNVDLKRISS 321
Cdd:PRK07048 243 YTFPIIRRLVDDIVTVSDAELVDAMRFFAERMKIVVEPTGCLGAAAALRGKVP--LKGKRVGVIISGGNVDLARFAA 317
|
|
| PRK06815 |
PRK06815 |
threonine/serine dehydratase; |
13-323 |
1.18e-85 |
|
threonine/serine dehydratase;
Pssm-ID: 180709 [Multi-domain] Cd Length: 317 Bit Score: 260.78 E-value: 1.18e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 13 IKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGVALS 92
Cdd:PRK06815 7 ILEAHQRLRPQVRVTPLEHSPLLSQHTGCEVYLKCEHLQHTGSFKFRGASNKLRLLNEAQRQQGVITASSGNHGQGVALA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 93 SHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDILDDM 172
Cdd:PRK06815 87 AKLAGIPVTVYAPEQASAIKLDAIRALGAEVRLYGGDALNAELAARRAAEQQGKVYISPYNDPQVIAGQGTIGMELVEQQ 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 173 WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKI-PGDLTFEIVK 251
Cdd:PRK06815 167 PDLDAVFVAVGGGGLISGIATYLKTLSPKTEIIGCWPANSPSLYTSLEAGEIVEVAEQPTLSDGTAGGVePGAITFPLCQ 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517597650 252 ELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKvDQYtKGKKVVAVISGGNVDLKRISSVC 323
Cdd:PRK06815 247 QLIDQKVLVSEEEIKEAMRLIAETDRWLIEGAAGVALAAALKLA-PRY-QGKKVAVVLCGKNIVLEKYLEAV 316
|
|
| PRK08639 |
PRK08639 |
threonine dehydratase; Validated |
3-330 |
2.99e-84 |
|
threonine dehydratase; Validated
Pssm-ID: 236318 [Multi-domain] Cd Length: 420 Bit Score: 260.51 E-value: 2.99e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 3 NKNLPLNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSA 82
Cdd:PRK08639 2 TVKMTVSAKDIDKAAKRLKDVVPETPLQRNDYLSEKYGANVYLKREDLQPVRSYKLRGAYNAISQLSDEELAAGVVCASA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 83 GNHAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGS---EVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMA 159
Cdd:PRK08639 82 GNHAQGVAYACRHLGIPGVIFMPVTTPQQKIDQVRFFGGefvEIVLVGDTFDDSAAAAQEYAEETGATFIPPFDDPDVIA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 160 GQGTIGLDILDDM---WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADG 236
Cdd:PRK08639 162 GQGTVAVEILEQLekeGSPDYVFVPVGGGGLISGVTTYLKERSPKTKIIGVEPAGAASMKAALEAGKPVTLEKIDKFVDG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 237 CAVKIPGDLTFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKvdQYTKGKKVVAVISGGNVDL 316
Cdd:PRK08639 242 AAVARVGDLTFEILKDVVDDVVLVPEGAVCTTILELYNKEGIVAEPAGALSIAALELYK--DEIKGKTVVCVISGGNNDI 319
|
330 340
....*....|....*....|...
gi 517597650 317 KRISSVCE---------HFFVAN 330
Cdd:PRK08639 320 ERMPEIKErsliyeglkHYFIVN 342
|
|
| PLN02970 |
PLN02970 |
serine racemase |
1-319 |
2.95e-82 |
|
serine racemase
Pssm-ID: 215524 [Multi-domain] Cd Length: 328 Bit Score: 252.29 E-value: 2.95e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 1 MINKNLPLNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIAC 80
Cdd:PLN02970 2 AASEKYAADLSSIREARKRIAPFIHRTPVLTSSSLDALAGRSLFFKCECFQKGGAFKFRGACNAIFSLSDDQAEKGVVTH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 81 SAGNHAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAG 160
Cdd:PLN02970 82 SSGNHAAALALAAKLRGIPAYIVVPKNAPACKVDAVIRYGGIITWCEPTVESREAVAARVQQETGAVLIHPYNDGRVISG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 161 QGTIGLDILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVK 240
Cdd:PLN02970 162 QGTIALEFLEQVPELDVIIVPISGGGLISGIALAAKAIKPSIKIIAAEPKGADDAAQSKAAGEIITLPVTNTIADGLRAS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 241 IpGDLTFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKV---DQYTKGKKVVAVISGGNVDLK 317
Cdd:PLN02970 242 L-GDLTWPVVRDLVDDVITVDDKEIIEAMKLCYERLKVVVEPSGAIGLAAALSDSFrsnPAWKGCKNVGIVLSGGNVDLG 320
|
..
gi 517597650 318 RI 319
Cdd:PLN02970 321 VL 322
|
|
| eutB |
PRK07476 |
threonine dehydratase; Provisional |
8-317 |
1.68e-78 |
|
threonine dehydratase; Provisional
Pssm-ID: 236025 [Multi-domain] Cd Length: 322 Bit Score: 242.56 E-value: 1.68e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 8 LNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQ 87
Cdd:PRK07476 1 VSLADIYRARRRIAGRVRRTPLVASASLSARAGVPVWLKLETLQPTGSFKLRGATNALLSLSAQERARGVVTASTGNHGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 88 GVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLD 167
Cdd:PRK07476 81 ALAYAARALGIRATICMSRLVPANKVDAIRALGAEVRIVGRSQDDAQAEVERLVREEGLTMVPPFDDPRIIAGQGTIGLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 168 ILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIAD--GCAVKIPGDL 245
Cdd:PRK07476 161 ILEALPDVATVLVPLSGGGLASGVAAAVKAIRPAIRVIGVSMERGAAMHASLAAGRPVQVEEVPTLADslGGGIGLDNRY 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517597650 246 TFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDqyTKGKKVVAVISGGNVDLK 317
Cdd:PRK07476 241 TFAMCRALLDDVVLLDEAEIAAGIRHAYREERLVVEGAGAVGIAALLAGKIA--ARDGPIVVVVSGANIDME 310
|
|
| PRK12483 |
PRK12483 |
threonine dehydratase; Reviewed |
24-324 |
3.51e-78 |
|
threonine dehydratase; Reviewed
Pssm-ID: 237111 [Multi-domain] Cd Length: 521 Bit Score: 248.17 E-value: 3.51e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 24 ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGVALSSHLLGIKSKIV 103
Cdd:PRK12483 35 ARETPLQRAPNLSARLGNQVLLKREDLQPVFSFKIRGAYNKMARLPAEQLARGVITASAGNHAQGVALAAARLGVKAVIV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 104 MPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDIL-DDMWDVDTVIVPI 182
Cdd:PRK12483 115 MPRTTPQLKVDGVRAHGGEVVLHGESFPDALAHALKLAEEEGLTFVPPFDDPDVIAGQGTVAMEILrQHPGPLDAIFVPV 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 183 GGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDLTFEIVKELVDDIVTVSE 262
Cdd:PRK12483 195 GGGGLIAGIAAYVKYVRPEIKVIGVEPDDSNCLQAALAAGERVVLGQVGLFADGVAVAQIGEHTFELCRHYVDEVVTVST 274
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517597650 263 EELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISGGNVDLKRISSVCE 324
Cdd:PRK12483 275 DELCAAIKDIYDDTRSITEPAGALAVAGIKKYAEREGIEGQTLVAIDSGANVNFDRLRHVAE 336
|
|
| PALP |
pfam00291 |
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate ... |
20-311 |
6.47e-70 |
|
Pyridoxal-phosphate dependent enzyme; Members of this family are all pyridoxal-phosphate dependent enzymes. This family includes: serine dehydratase EC:4.2.1.13 P20132, threonine dehydratase EC:4.2.1.16, tryptophan synthase beta chain EC:4.2.1.20, threonine synthase EC:4.2.99.2, cysteine synthase EC:4.2.99.8 P11096, cystathionine beta-synthase EC:4.2.1.22, 1-aminocyclopropane-1-carboxylate deaminase EC:4.1.99.4.
Pssm-ID: 459749 [Multi-domain] Cd Length: 295 Bit Score: 219.87 E-value: 6.47e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 20 LSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGVALSSHLLGIK 99
Cdd:pfam00291 1 ISLGIGPTPLVRLPRLSKELGVDVYLKLESLNPTGSFKDRGALNLLLRLKEGEGGKTVVEASSGNHGRALAAAAARLGLK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 100 SKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGE-TYLHPYDDVEVMAGQGTIGLDILDDMW-DVDT 177
Cdd:pfam00291 81 VTIVVPEDAPPGKLLLMRALGAEVVLVGGDYDEAVAAARELAAEGPGaYYINQYDNPLNIEGYGTIGLEILEQLGgDPDA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 178 VIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKI-PGDLTFEIVKELVDD 256
Cdd:pfam00291 161 VVVPVGGGGLIAGIARGLKELGPDVRVIGVEPEGAPALARSLAAGRPVPVPVADTIADGLGVGDePGALALDLLDEYVGE 240
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 517597650 257 IVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISG 311
Cdd:pfam00291 241 VVTVSDEEALEAMRLLARREGIVVEPSSAAALAALKLALAGELKGGDRVVVVLTG 295
|
|
| ectoine_eutB |
TIGR02991 |
ectoine utilization protein EutB; Members of this protein family are EutB, a predicted ... |
8-319 |
8.01e-66 |
|
ectoine utilization protein EutB; Members of this protein family are EutB, a predicted arylmalonate decarboxylase found in a conserved ectoine utilization operon of species that include Sinorhizobium meliloti 1021 (where it is known to be induced by ectoine), Mesorhizobium loti, Silicibacter pomeroyi, Agrobacterium tumefaciens, and Pseudomonas putida. Members of this family resemble threonine dehydratases.
Pssm-ID: 132036 [Multi-domain] Cd Length: 317 Bit Score: 210.09 E-value: 8.01e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 8 LNIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQ 87
Cdd:TIGR02991 1 VTLQDIERAAARISGRVEETPLVESPSLSELCGVPVHLKLEHRQTTGSFKLRGATNAVLSLSDTQRAAGVVAASTGNHGR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 88 GVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLD 167
Cdd:TIGR02991 81 ALAYAAAEEGVRATICMSELVPQNKVDEIRRLGAEVRIVGRSQDDAQEEVERLVADRGLTMLPPFDHPDIVAGQGTLGLE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 168 ILDDMWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIAD--GCAVKIPGDL 245
Cdd:TIGR02991 161 VVEQMPDLATVLVPLSGGGLASGVAMAVKAARPDTRVIGVSMERGAAMKASLQAGRPVLVAELPTLADslGGGIGLDNRV 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517597650 246 TFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDqyTKGKKVVaVISGGNVDL---KRI 319
Cdd:TIGR02991 241 TFAMCKALLDEIVLVSEAEIAAGIRHAYAEEREIVEGAGAVGIAALLAGKIK--NPGPCAV-IVSGRNIDMdlhKRI 314
|
|
| PRK08246 |
PRK08246 |
serine/threonine dehydratase; |
12-281 |
9.01e-56 |
|
serine/threonine dehydratase;
Pssm-ID: 181319 [Multi-domain] Cd Length: 310 Bit Score: 183.62 E-value: 9.01e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 12 DIKKAQQILSGNARKTPLVKSfYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKIsnLTDEEKAHGVIACSAGNHAQGVAL 91
Cdd:PRK08246 9 DVRAAAQRIAPHIRRTPVLEA-DGAGFGPAPVWLKLEHLQHTGSFKARGAFNRL--LAAPVPAAGVVAASGGNAGLAVAY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 92 SSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDILDD 171
Cdd:PRK08246 86 AAAALGVPATVFVPETAPPAKVARLRALGAEVVVVGAEYADALEAAQAFAAETGALLCHAYDQPEVLAGAGTLGLEIEEQ 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 172 MWDVDTVivpiggggiisgiAVA----------LKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKI 241
Cdd:PRK08246 166 APGVDTV-------------LVAvggggliagiAAWFEGRARVVAVEPEGAPTLHAALAAGEPVDVPVSGIAADSLGARR 232
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 517597650 242 PGDLTFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVE 281
Cdd:PRK08246 233 VGEIAFALARAHVVTSVLVSDEAIIAARRALWEELRLAVE 272
|
|
| PLN02550 |
PLN02550 |
threonine dehydratase |
18-324 |
2.19e-55 |
|
threonine dehydratase
Pssm-ID: 178165 [Multi-domain] Cd Length: 591 Bit Score: 189.75 E-value: 2.19e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 18 QILSGN----ARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGNHAQGVALSS 93
Cdd:PLN02550 97 NILSAKvydvAIESPLQLAKKLSERLGVKVLLKREDLQPVFSFKLRGAYNMMAKLPKEQLDKGVICSSAGNHAQGVALSA 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 94 HLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDILDDMW 173
Cdd:PLN02550 177 QRLGCDAVIAMPVTTPEIKWQSVERLGATVVLVGDSYDEAQAYAKQRALEEGRTFIPPFDHPDVIAGQGTVGMEIVRQHQ 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 174 D-VDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDLTFEIVKE 252
Cdd:PLN02550 257 GpLHAIFVPVGGGGLIAGIAAYVKRVRPEVKIIGVEPSDANAMALSLHHGERVMLDQVGGFADGVAVKEVGEETFRLCRE 336
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 517597650 253 LVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISGGNVDLKRISSVCE 324
Cdd:PLN02550 337 LVDGVVLVSRDAICASIKDMFEEKRSILEPAGALALAGAEAYCKYYGLKDENVVAITSGANMNFDRLRIVTE 408
|
|
| Trp-synth-beta_II |
cd00640 |
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP) ... |
27-312 |
6.34e-52 |
|
Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan synthase beta chain (Trp-synth_B), cystathionine beta-synthase (CBS), O-acetylserine sulfhydrylase (CS), serine dehydratase (Ser-dehyd), threonine dehydratase (Thr-dehyd), diaminopropionate ammonia lyase (DAL), and threonine synthase (Thr-synth). ACCD catalyzes the conversion of 1-aminocyclopropane-1-carboxylate to alpha-ketobutyrate and ammonia. Tryptophan synthase folds into a tetramer, where the beta chain is the catalytic PLP-binding subunit and catalyzes the formation of L-tryptophan from indole and L-serine. CBS is a tetrameric hemeprotein that catalyzes condensation of serine and homocysteine to cystathionine. CS is a homodimer that catalyzes the formation of L-cysteine from O-acetyl-L-serine. Ser-dehyd catalyzes the conversion of L- or D-serine to pyruvate and ammonia. Thr-dehyd is active as a homodimer and catalyzes the conversion of L-threonine to 2-oxobutanoate and ammonia. DAL is also a homodimer and catalyzes the alpha, beta-elimination reaction of both L- and D-alpha, beta-diaminopropionate to form pyruvate and ammonia. Thr-synth catalyzes the formation of threonine and inorganic phosphate from O-phosphohomoserine.
Pssm-ID: 107202 [Multi-domain] Cd Length: 244 Bit Score: 171.54 E-value: 6.34e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEK-AHGVIACSA-GNHAQGVALSSHLLGIKSKIVM 104
Cdd:cd00640 1 TPLVRLKRLSKLGGANIYLKLEFLNPTGSFKDRGALNLILLAEEEGKlPKGVIIESTgGNTGIALAAAAARLGLKCTIVM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 105 PISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGE-TYLHPYDDVEVMAGQGTIGLDILDDMWD--VDTVIVP 181
Cdd:cd00640 81 PEGASPEKVAQMRALGAEVVLVPGDFDDAIALAKELAEEDPGaYYVNQFDNPANIAGQGTIGLEILEQLGGqkPDAVVVP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 182 IGGGGIISGIAVALKSFNPSINIIGVQAdnvhgmkasydvgkivshyeaptiadgcavkipgdltfeivkelvdDIVTVS 261
Cdd:cd00640 161 VGGGGNIAGIARALKELLPNVKVIGVEP----------------------------------------------EVVTVS 194
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 517597650 262 EEELEVAMKDLLQRGKAVVEGAGALATAALLAGKvDQYTKGKKVVAVISGG 312
Cdd:cd00640 195 DEEALEAIRLLAREEGILVEPSSAAALAAALKLA-KKLGKGKTVVVILTGG 244
|
|
| PRK08813 |
PRK08813 |
threonine dehydratase; Provisional |
5-315 |
3.05e-51 |
|
threonine dehydratase; Provisional
Pssm-ID: 236339 [Multi-domain] Cd Length: 349 Bit Score: 173.27 E-value: 3.05e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 5 NLPLNIGDIKKAQQILSGNARKTPLvksfYLTSKTGgeIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHGVIACSAGN 84
Cdd:PRK08813 18 DVAVSVADVLAAQARLRRYLSPTPL----HYAERFG--VWLKLENLQRTGSYKVRGALNALLAGLERGDERPVICASAGN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 85 HAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTI 164
Cdd:PRK08813 92 HAQGVAWSAYRLGVQAITVMPHGAPQTKIAGVAHWGATVRQHGNSYDEAYAFARELADQNGYRFLSAFDDPDVIAGQGTV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 165 GLDILDDMWDVdtVIVPIGGGGIISGIAVALKSfnPSINIIGVQADNVHGMkASYDVGKIVSHYEAPTIADGCAVKIPGD 244
Cdd:PRK08813 172 GIELAAHAPDV--VIVPIGGGGLASGVALALKS--QGVRVVGAQVEGVDSM-ARAIRGDLREIAPVATLADGVKVKIPGF 246
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517597650 245 LTFEIVKELVDDIVTVSEEELEVAMKDLlqrgkaVVEGAGALATAALLAGKVDQYTKGKKVVAVISGGNVD 315
Cdd:PRK08813 247 LTRRLCSSLLDDVVIVREAELRETLVRL------ALEEHVIAEGAGALALAAGRRVSGKRKCAVVSGGNID 311
|
|
| PRK06608 |
PRK06608 |
serine/threonine dehydratase; |
5-315 |
3.83e-50 |
|
serine/threonine dehydratase;
Pssm-ID: 235842 [Multi-domain] Cd Length: 338 Bit Score: 169.95 E-value: 3.83e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 5 NLPL-NIGDIKKAQQILSGNARKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEK-AHGVIACSA 82
Cdd:PRK06608 1 NLLLqNPQNIAAAHNRIKQYLHLTPIVHSESLNEMLGHEIFFKVESLQKTGAFKVRGVLNHLLELKEQGKlPDKIVAYST 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 83 GNHAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHgDTFDDAKAKCEEiIQETGETYLHPYDDVEVMAGQG 162
Cdd:PRK06608 81 GNHGQAVAYASKLFGIKTRIYLPLNTSKVKQQAALYYGGEVILT-NTRQEAEEKAKE-DEEQGFYYIHPSDSDSTIAGAG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 163 TIGLDILDDM-WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAP-TIADGCAVK 240
Cdd:PRK06608 159 TLCYEALQQLgFSPDAIFASCGGGGLISGTYLAKELISPTSLLIGSEPLNANDAYLSLKNNKIYRLNYSPnTIADGLKTL 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517597650 241 IPGDLTFEIVKELvDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQyTKGKKVVAVISGGNVD 315
Cdd:PRK06608 239 SVSARTFEYLKKL-DDFYLVEEYEIYYWTAWLTHLLKVICEPSSAINMVAVVNWLKTQ-SKPQKLLVILSGGNID 311
|
|
| PRK06110 |
PRK06110 |
threonine dehydratase; |
35-322 |
2.21e-33 |
|
threonine dehydratase;
Pssm-ID: 235699 Cd Length: 322 Bit Score: 125.49 E-value: 2.21e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 35 LTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEE-KAHGVIACSAGNHAQGVALSSHLLGIKSKIVMPISAPQAKV 113
Cdd:PRK06110 30 LAERLGCEVWVKHENHTPTGAFKVRGGLVYFDRLARRGpRVRGVISATRGNHGQSVAFAARRHGLAATIVVPHGNSVEKN 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 114 DATRGYGSEVILHGDTFDDAKAKCEEIIQETGetyLH--PYDDVEVMAGQGTIGLDILDDMWDVDTVIVPIGGGGIISGI 191
Cdd:PRK06110 110 AAMRALGAELIEHGEDFQAAREEAARLAAERG---LHmvPSFHPDLVRGVATYALELFRAVPDLDVVYVPIGMGSGICGA 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 192 AVALKSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGDLTFEIVKELVDDIVTVSEEELEVAMKD 271
Cdd:PRK06110 187 IAARDALGLKTRIVGVVSAHAPAYALSFEAGRVVTTPVATTLADGMACRTPDPEALEVIRAGADRIVRVTDDEVAAAMRA 266
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 517597650 272 LLQRGKAVVEGAGALATAALLAGKVDQytKGKKVVAVISGGNVDLKRISSV 322
Cdd:PRK06110 267 YFTDTHNVAEGAGAAALAAALQERERL--AGKRVGLVLSGGNIDRAVFARV 315
|
|
| L-Ser-dehyd |
cd06448 |
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the ... |
26-281 |
1.79e-24 |
|
Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- , D-serine, or L-threonine to pyruvate/ketobutyrate and ammonia.
Pssm-ID: 107209 Cd Length: 316 Bit Score: 101.22 E-value: 1.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 26 KTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDE---EKAHgVIACSAGNHAQGVALSSHLLGIKSKI 102
Cdd:cd06448 1 KTPLIESTALSKTAGCNVFLKLENLQPSGSFKIRGIGHLCQKSAKQglnECVH-VVCSSGGNAGLAAAYAARKLGVPCTI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 103 VMPISAPQAKVDATRGYGSEVILHGDT-FDDAKAKCEEII-QETGETYLHPYDDVEVMAGQGTIGLDILDDMWDVDTViv 180
Cdd:cd06448 80 VVPESTKPRVVEKLRDEGATVVVHGKVwWEADNYLREELAeNDPGPVYVHPFDDPLIWEGHSSMVDEIAQQLQSQEKV-- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 181 piggggiisgIAVAL----------------KSFNPSINIIGVQADNVHGMKASYDVGKIVSHYEAPTIADGCAVKIPGD 244
Cdd:cd06448 158 ----------DAIVCsvggggllngivqgleRNGWGDIPVVAVETEGAHSLNASLKAGKLVTLPKITSVATSLGAKTVSS 227
|
250 260 270
....*....|....*....|....*....|....*..
gi 517597650 245 LTFEIVKELVDDIVTVSEEELEVAMKDLLQRGKAVVE 281
Cdd:cd06448 228 QALEYAQEHNIKSEVVSDRDAVQACLRFADDERILVE 264
|
|
| Thr-synth_1 |
cd01563 |
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last ... |
27-272 |
2.36e-18 |
|
Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants, OPH is an intermediate between the methionine and threonine/isoleucine pathways. Thus threonine synthase competes for OPH with cystathionine-gamma-synthase, the first enzyme in the methionine pathway. These enzymes are in general dimers. Members of this CD, Thr-synth_1, are widely distributed in bacteria, archaea and higher plants.
Pssm-ID: 107206 [Multi-domain] Cd Length: 324 Bit Score: 84.18 E-value: 2.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSFYLTSKTGG-EIHLKLENMQLTGSFKFRGAFNKISNLTdEEKAHGVIACSAGNHAQGVALSSHLLGIKSKIVMP 105
Cdd:cd01563 23 TPLVRAPRLGERLGGkNLYVKDEGLNPTGSFKDRGMTVAVSKAK-ELGVKAVACASTGNTSASLAAYAARAGIKCVVFLP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 106 ISAPQAKVDATRGYGSEVI-LHGDtFDDAKAKCEEIIQETG---ETYLHPYDdVEvmaGQGTIGLDILDDM-WDV-DTVI 179
Cdd:cd01563 102 AGKALGKLAQALAYGATVLaVEGN-FDDALRLVRELAEENWiylSNSLNPYR-LE---GQKTIAFEIAEQLgWEVpDYVV 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 180 VPIGGGGIISGIAVALKSF--------NPSIniIGVQADNVHGMKASYDVGK--IVSHYEAPTIADGCAVKIP--GDLTF 247
Cdd:cd01563 177 VPVGNGGNITAIWKGFKELkelglidrLPRM--VGVQAEGAAPIVRAFKEGKddIEPVENPETIATAIRIGNPasGPKAL 254
|
250 260
....*....|....*....|....*
gi 517597650 248 EIVKELVDDIVTVSEEELEVAMKDL 272
Cdd:cd01563 255 RAVRESGGTAVAVSDEEILEAQKLL 279
|
|
| CBS_like |
cd01561 |
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS ... |
26-275 |
5.01e-18 |
|
CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine. Deficiency of CBS leads to homocystinuria, an inherited disease of sulfur metabolism characterized by increased levels of the toxic metabolite homocysteine. Cysteine synthase on the other hand catalyzes the last step of cysteine biosynthesis. This subgroup also includes an O-Phosphoserine sulfhydrylase found in hyperthermophilic archaea which produces L-cysteine from sulfide and the more thermostable O-phospho-L-serine.
Pssm-ID: 107204 [Multi-domain] Cd Length: 291 Bit Score: 82.56 E-value: 5.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 26 KTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEEKAHG---VIACSAGNHAQGVALSSHLLGIKSKI 102
Cdd:cd01561 2 NTPLVRLNRLSPGTGAEIYAKLEFFNPGGSVKDRIALYMIEDAEKRGLLKPgttIIEPTSGNTGIGLAMVAAAKGYRFII 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 103 VMPISAPQAKVDATRGYGSEVIL----HGDTFDDAKAKCEEIIQETGETY-LHPYD-DVEVMAGQGTIGLDILDDM-WDV 175
Cdd:cd01561 82 VMPETMSEEKRKLLRALGAEVILtpeaEADGMKGAIAKARELAAETPNAFwLNQFEnPANPEAHYETTAPEIWEQLdGKV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 176 DTVivpiggggiisgiaVA--------------LKSFNPSINIIGVQADNvhgmKASYDVGKIVSHyeaptiadgcavKI 241
Cdd:cd01561 162 DAF--------------VAgvgtggtitgvaryLKEKNPNVRIVGVDPVG----SVLFSGGPPGPH------------KI 211
|
250 260 270
....*....|....*....|....*....|....*...
gi 517597650 242 PG---DLTFEIVK-ELVDDIVTVSEEELEVAMKDLLQR 275
Cdd:cd01561 212 EGigaGFIPENLDrSLIDEVVRVSDEEAFAMARRLARE 249
|
|
| CysK |
COG0031 |
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the ... |
27-275 |
3.32e-14 |
|
Cysteine synthase [Amino acid transport and metabolism]; Cysteine synthase is part of the Pathway/BioSystem: Cysteine biosynthesis
Pssm-ID: 439802 [Multi-domain] Cd Length: 301 Bit Score: 72.00 E-value: 3.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKIsnlTDEEKA------HGVIACSAGNHAQGVALSSHLLGIKS 100
Cdd:COG0031 14 TPLVRLNRLSPGPGAEIYAKLESFNPGGSVKDRIALSMI---EDAEKRgllkpgGTIVEATSGNTGIGLAMVAAAKGYRL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 101 KIVMPISAPQAKVDATRGYGSEVIL--HGDTFDDAKAKCEEIIQETGETYlhpyddvevMAGQ-----------GTIGLD 167
Cdd:COG0031 91 ILVMPETMSKERRALLRAYGAEVVLtpGAEGMKGAIDKAEELAAETPGAF---------WPNQfenpanpeahyETTGPE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 168 ILDDMW-DVDTVivpiggggiisgiaVA--------------LKSFNPSINIIGVQADNvhgmKASYDVGKIVSHyeapt 232
Cdd:COG0031 162 IWEQTDgKVDAF--------------VAgvgtggtitgvgryLKERNPDIKIVAVEPEG----SPLLSGGEPGPH----- 218
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 517597650 233 iadgcavKIPGdLTFEIV-----KELVDDIVTVSEEELEVAMKDLLQR 275
Cdd:COG0031 219 -------KIEG-IGAGFVpkildPSLIDEVITVSDEEAFAMARRLARE 258
|
|
| PRK05638 |
PRK05638 |
threonine synthase; Validated |
27-311 |
6.35e-12 |
|
threonine synthase; Validated
Pssm-ID: 235539 [Multi-domain] Cd Length: 442 Bit Score: 65.99 E-value: 6.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSfYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTDEeKAHGVIACSAGNHAQGVALSSHLLGIKSKIVMPI 106
Cdd:PRK05638 67 TPLIRA-RISEKLGENVYIKDETRNPTGSFRDRLATVAVSYGLPY-AANGFIVASDGNAAASVAAYSARAGKEAFVVVPR 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 107 SAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGETYLHPYDDVEVMAGQGTIGLDILDDMWDVDTVIVPIGGGG 186
Cdd:PRK05638 145 KVDKGKLIQMIAFGAKIIRYGESVDEAIEYAEELARLNGLYNVTPEYNIIGLEGQKTIAFELWEEINPTHVIVPTGSGSY 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 187 IISGiavaLKSFNPSINI---------IGVQADN-------VHGMKASYDvgkivshyeaPTIADGCAVKIP--GDLTFE 248
Cdd:PRK05638 225 LYSI----YKGFKELLEIgvieeipklIAVQTERcnpiaseILGNKTKCN----------ETKALGLYVKNPvmKEYVSE 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517597650 249 IVKELVDDIVTVSEEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISG 311
Cdd:PRK05638 291 AIKESGGTAVVVNEEEIMAGEKLLAKEGIFAELSSAVVMPALLKLGEEGYIEKGDKVVLVVTG 353
|
|
| ThrC |
COG0498 |
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the ... |
27-275 |
2.35e-11 |
|
Threonine synthase [Amino acid transport and metabolism]; Threonine synthase is part of the Pathway/BioSystem: Threonine biosynthesis
Pssm-ID: 440264 [Multi-domain] Cd Length: 394 Bit Score: 64.07 E-value: 2.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAF---NKIsnltdeeKAHG--VIAC-SAGNHAQGVALSSHLLGIKS 100
Cdd:COG0498 67 TPLVKAPRLADELGKNLYVKEEGHNPTGSFKDRAMQvavSLA-------LERGakTIVCaSSGNGSAALAAYAARAGIEV 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 101 KIVMPIS-APQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGeTYL----HPYddveVMAGQGTIGLDILDDMWDV 175
Cdd:COG0498 140 FVFVPEGkVSPGQLAQMLTYGAHVIAVDGNFDDAQRLVKELAADEG-LYAvnsiNPA----RLEGQKTYAFEIAEQLGRV 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 176 -DTVIVPIGGGGIISGIAVALKSFNPS--IN----IIGVQADNVHGMKASYDVGKIVSHYEAP-TIADGCAVKIPGDLtF 247
Cdd:COG0498 215 pDWVVVPTGNGGNILAGYKAFKELKELglIDrlprLIAVQATGCNPILTAFETGRDEYEPERPeTIAPSMDIGNPSNG-E 293
|
250 260 270
....*....|....*....|....*....|.
gi 517597650 248 EIVKELVD---DIVTVSEEELEVAMKDLLQR 275
Cdd:COG0498 294 RALFALREsggTAVAVSDEEILEAIRLLARR 324
|
|
| PRK08197 |
PRK08197 |
threonine synthase; Validated |
13-175 |
1.04e-10 |
|
threonine synthase; Validated
Pssm-ID: 181283 [Multi-domain] Cd Length: 394 Bit Score: 62.33 E-value: 1.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 13 IKKAQQILSGNARKTPLVKSFYLTSKTG-GEIHLKLENMQLTGSFKFRGAFNKISnltdEEKAHGV--IAC-SAGNHAQG 88
Cdd:PRK08197 66 VRDPEHIVSLGEGMTPLLPLPRLGKALGiGRLWVKDEGLNPTGSFKARGLAVGVS----RAKELGVkhLAMpTNGNAGAA 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 89 VALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETG----ETYLHPYdDVEvmaGQGTI 164
Cdd:PRK08197 142 WAAYAARAGIRATIFMPADAPEITRLECALAGAELYLVDGLISDAGKIVAEAVAEYGwfdvSTLKEPY-RIE---GKKTM 217
|
170
....*....|..
gi 517597650 165 GLDILDDM-WDV 175
Cdd:PRK08197 218 GLELAEQLgWRL 229
|
|
| PRK08206 |
PRK08206 |
diaminopropionate ammonia-lyase; Provisional |
8-172 |
1.36e-10 |
|
diaminopropionate ammonia-lyase; Provisional
Pssm-ID: 236186 Cd Length: 399 Bit Score: 61.82 E-value: 1.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 8 LNIGDIKKAQQILSG--NARKTPLVKSFYLTSKTG-GEIHLKLENMQL-TGSFKFRGA-----------FNK------IS 66
Cdd:PRK08206 24 LSQEEAKKARAFHQSfpGYAPTPLVALPDLAAELGvGSILVKDESYRFgLNAFKALGGayavarllaekLGLdiselsFE 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 67 NLTDEEK----AHGVIAC-SAGNHAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDTFDD--------A 133
Cdd:PRK08206 104 ELTSGEVreklGDITFATaTDGNHGRGVAWAAQQLGQKAVIYMPKGSSEERVDAIRALGAECIITDGNYDDsvrlaaqeA 183
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 517597650 134 KAKCEEIIQET---GetylhpYDDV--EVMAGQGTIGLDILDDM 172
Cdd:PRK08206 184 QENGWVVVQDTaweG------YEEIptWIMQGYGTMADEAVEQL 221
|
|
| PRK08329 |
PRK08329 |
threonine synthase; Validated |
36-316 |
1.75e-09 |
|
threonine synthase; Validated
Pssm-ID: 236244 [Multi-domain] Cd Length: 347 Bit Score: 58.30 E-value: 1.75e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 36 TSKTGGEIHLKLENMQLTGSFKFRGAFNKISNLTdEEKAHGVIACSAGNHAQGVALSSHLLGIKSKIVMPISAPQAKVDA 115
Cdd:PRK08329 67 TVKRSIKVYFKLDYLQPTGSFKDRGTYVTVAKLK-EEGINEVVIDSSGNAALSLALYSLSEGIKVHVFVSYNASKEKISL 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 116 TRGYGSEV-ILHGDTFDDAKaKCEEIIQETGETY----LHPYddveVMAGQGTIGLDILDDMWDVDTVIVPIGGGGIISG 190
Cdd:PRK08329 146 LSRLGAELhFVEGDRMEVHE-EAVKFSKRNNIPYvshwLNPY----FLEGTKTIAYEIYEQIGVPDYAFVPVGSGTLFLG 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 191 IAVALKSF------NPSINIIGVQADNVHGM-KASYDVGKivshyeaptIADGCAVKIPG--DLTFEIVKELVDDIVTVS 261
Cdd:PRK08329 221 IWKGFKELhemgeiSKMPKLVAVQAEGYESLcKRSKSENK---------LADGIAIPEPPrkEEMLRALEESNGFCISVG 291
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 517597650 262 EEELEVAMKDLLQRGKAVVEGAGALATAALLAGKVDQYTKGKKVVAVISGGNVDL 316
Cdd:PRK08329 292 EEETRAALHWLRRMGFLVEPTSAVALAAYWKLLEEGLIEGGSKVLLPLSGSGLKN 346
|
|
| cysM |
PRK11761 |
cysteine synthase CysM; |
22-272 |
4.97e-08 |
|
cysteine synthase CysM;
Pssm-ID: 236972 Cd Length: 296 Bit Score: 53.34 E-value: 4.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 22 GNarkTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKISnltdEEKAHGVI--------ACSaGNhaQGVALS- 92
Cdd:PRK11761 11 GN---TPLVKLQRLPPDRGNTILAKLEGNNPAGSVKDRPALSMIV----QAEKRGEIkpgdtlieATS-GN--TGIALAm 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 93 -SHLLGIKSKIVMPISAPQAKVDATRGYGSEVIL-------------------HG-----DTF---DDAKAKCE----EI 140
Cdd:PRK11761 81 iAAIKGYRMKLIMPENMSQERRAAMRAYGAELILvpkeqgmegardlalqmqaEGegkvlDQFanpDNPLAHYEttgpEI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 141 IQETGETYLHpydDVEVMAGQGTIgldilddmwdvdtvivpiggggiiSGIAVALKSFNPSINIIGVQadnvhgmkasyd 220
Cdd:PRK11761 161 WRQTEGRITH---FVSSMGTTGTI------------------------MGVSRYLKEQNPAVQIVGLQ------------ 201
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517597650 221 vgkivshyeaPtiADGCAvkIPGdltfeIVK------------ELVDDIVTVSEEELEVAMKDL 272
Cdd:PRK11761 202 ----------P--EEGSS--IPG-----IRRwpeeylpkifdaSRVDRVLDVSQQEAENTMRRL 246
|
|
| PRK06450 |
PRK06450 |
threonine synthase; Validated |
27-276 |
5.44e-08 |
|
threonine synthase; Validated
Pssm-ID: 180565 [Multi-domain] Cd Length: 338 Bit Score: 53.59 E-value: 5.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKsfyltsktGGEIHLKLENMQLTGSFKFRGAFNKISNLTDeeKAHGVIA-CSAGNHAQGVALSSHLLGIKSKIVMP 105
Cdd:PRK06450 59 TPLIK--------KGNIWFKLDFLNPTGSYKDRGSVTLISYLAE--KGIKQISeDSSGNAGASIAAYGAAAGIEVKIFVP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 106 ISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEeiiqETGETY----LHPyddvEVMAGQGTIGLDILDDM-WDV-DTVI 179
Cdd:PRK06450 129 ETASGGKLKQIESYGAEVVRVRGSREDVAKAAE----NSGYYYashvLQP----QFRDGIRTLAYEIAKDLdWKIpNYVF 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 180 VPIGGGGIISGIAVALKS-FNPSI-----NIIGVQADNVHGMKA-----SYDVGKIVShyeapTIADGCAVKIPGdLTFE 248
Cdd:PRK06450 201 IPVSAGTLLLGVYSGFKHlLDSGVisempKIVAVQTEQVSPLCAkfkgiSYTPPDKVT-----SIADALVSTRPF-LLDY 274
|
250 260 270
....*....|....*....|....*....|
gi 517597650 249 IVKEL--VDDIVTVSEEELEVAMKDLLQRG 276
Cdd:PRK06450 275 MVKALseYGECIVVSDNEIVEAWKELAKKG 304
|
|
| PRK10717 |
PRK10717 |
cysteine synthase A; Provisional |
27-125 |
2.03e-07 |
|
cysteine synthase A; Provisional
Pssm-ID: 182672 [Multi-domain] Cd Length: 330 Bit Score: 51.79 E-value: 2.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAFNKIsnlTDEE-----KAHGVIA-CSAGNHAQGVALSSHLLGIKS 100
Cdd:PRK10717 14 TPLIRLNRASEATGCEILGKAEFLNPGGSVKDRAALNII---WDAEkrgllKPGGTIVeGTAGNTGIGLALVAAARGYKT 90
|
90 100
....*....|....*....|....*
gi 517597650 101 KIVMPISAPQAKVDATRGYGSEVIL 125
Cdd:PRK10717 91 VIVMPETQSQEKKDLLRALGAELVL 115
|
|
| PRK06381 |
PRK06381 |
threonine synthase; Validated |
27-175 |
5.12e-07 |
|
threonine synthase; Validated
Pssm-ID: 235789 Cd Length: 319 Bit Score: 50.47 E-value: 5.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 27 TPLVKSFYLTSKTG-GEIHLKLENMQLTGSFKFRGAFNKISNLTDEeKAHGVIACSAGNHAQGVALSSHLLGIKSKIVMP 105
Cdd:PRK06381 16 TPLLRARKLEEELGlRKIYLKFEGANPTGTQKDRIAEAHVRRAMRL-GYSGITVGTCGNYGASIAYFARLYGLKAVIFIP 94
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517597650 106 ISAPQAKVDATRGYGSEVILHGDTFDDAKAKCEEIIQETGeTY------LHPYDDVEvmaGQGTIGLDILDDMWDV 175
Cdd:PRK06381 95 RSYSNSRVKEMEKYGAEIIYVDGKYEEAVERSRKFAKENG-IYdanpgsVNSVVDIE---AYSAIAYEIYEALGDV 166
|
|
| PLN03013 |
PLN03013 |
cysteine synthase |
8-279 |
1.38e-05 |
|
cysteine synthase
Pssm-ID: 178587 [Multi-domain] Cd Length: 429 Bit Score: 46.31 E-value: 1.38e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 8 LNIGDikKAQQILSgnarKTPLVksfYLTSKTGG---EIHLKLENMQLTGSFKFRGAFnkiSNLTDEEKAHGV------- 77
Cdd:PLN03013 111 LNIAD--NVSQLIG----KTPMV---YLNSIAKGcvaNIAAKLEIMEPCCSVKDRIGY---SMVTDAEQKGFIspgksvl 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 78 IACSAGNHAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILH--GDTFDDAKAKCEEIIQETGETY-LHPYDD 154
Cdd:PLN03013 179 VEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTdpAKGMTGAVQKAEEILKNTPDAYmLQQFDN 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 155 -VEVMAGQGTIGLDILDDM-WDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGV---QADNVHGmkasydvGKIVSHye 229
Cdd:PLN03013 259 pANPKIHYETTGPEIWDDTkGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVeptESDILSG-------GKPGPH-- 329
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 517597650 230 apTIADGCAVKIPGDLTFEIVKELvddIVTVSEEELEVAMKDLLQRGKAV 279
Cdd:PLN03013 330 --KIQGIGAGFIPKNLDQKIMDEV---IAISSEEAIETAKQLALKEGLMV 374
|
|
| PLN02556 |
PLN02556 |
cysteine synthase/L-3-cyanoalanine synthase |
4-208 |
6.83e-05 |
|
cysteine synthase/L-3-cyanoalanine synthase
Pssm-ID: 178171 [Multi-domain] Cd Length: 368 Bit Score: 44.18 E-value: 6.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 4 KNLPLNigDIKKAQQILSGnarKTPLVKSFYLTSKTGGEIHLKLENMQLTGSFKFRGAfnkISNLTDEEKAH-------G 76
Cdd:PLN02556 42 KDLPGT--KIKTDASQLIG---KTPLVYLNKVTEGCGAYIAAKQEMFQPTSSIKDRPA---LAMIEDAEKKNlitpgktT 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 77 VIACSAGNHAQGVALSSHLLGIKSKIVMPISAPQAKVDATRGYGSEVILHGDT--FDDAKAKCEEIIQETGETY-LHPYD 153
Cdd:PLN02556 114 LIEPTSGNMGISLAFMAAMKGYKMILTMPSYTSLERRVTMRAFGAELVLTDPTkgMGGTVKKAYELLESTPDAFmLQQFS 193
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 517597650 154 D-VEVMAGQGTIGLDILDD-MWDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQ 208
Cdd:PLN02556 194 NpANTQVHFETTGPEIWEDtLGQVDIFVMGIGSGGTVSGVGKYLKSKNPNVKIYGVE 250
|
|
| PLN02565 |
PLN02565 |
cysteine synthase |
26-279 |
2.82e-04 |
|
cysteine synthase
Pssm-ID: 166206 Cd Length: 322 Bit Score: 42.22 E-value: 2.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 26 KTPLVksfYLTSKTGG---EIHLKLENMQLTGSFKFRGAFNKISNLtdEEKA------HGVIACSAGNHAQGVALSSHLL 96
Cdd:PLN02565 15 KTPLV---YLNNVVDGcvaRIAAKLEMMEPCSSVKDRIGYSMITDA--EEKGlikpgeSVLIEPTSGNTGIGLAFMAAAK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 97 GIKSKIVMPISAPQAKVDATRGYGSEVILHGDT--FDDAKAKCEEIIQETGETYL--------HP---YDDVEVMAGQGT 163
Cdd:PLN02565 90 GYKLIITMPASMSLERRIILLAFGAELVLTDPAkgMKGAVQKAEEILAKTPNSYIlqqfenpaNPkihYETTGPEIWKGT 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517597650 164 IGldilddmwDVDTVIVPIGGGGIISGIAVALKSFNPSINIIGVQADNvhgmKASYDVGKIVSHyeapTIADGCAVKIPG 243
Cdd:PLN02565 170 GG--------KVDAFVSGIGTGGTITGAGKYLKEQNPDIKLYGVEPVE----SAVLSGGKPGPH----KIQGIGAGFIPG 233
|
250 260 270
....*....|....*....|....*....|....*..
gi 517597650 244 DLTFeivkELVDDIVTVSEEE-LEVAMKDLLQRGKAV 279
Cdd:PLN02565 234 VLDV----DLLDEVVQVSSDEaIETAKLLALKEGLLV 266
|
|
| |
