NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|517709709|ref|WP_018879917|]
View 

NAD(P)/FAD-dependent oxidoreductase [Thioalkalivibrio sp. ALE9]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11428914)

NAD(P)/FAD-dependent oxidoreductase similar to digeranylgeranylglycerophospholipid reductase, menaquinone reductase, tryptophan 2-halogenase, and protein FixC

CATH:  3.50.50.60|3.40.50.720|3.30.9.10
EC:  1.-.-.-
Gene Ontology:  GO:0000166|GO:0071949|GO:0016491
PubMed:  30945211
SCOP:  3000055

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
21-357 4.20e-57

Dehydrogenase (flavoprotein) [Energy production and conversion];


:

Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 189.79  E-value: 4.20e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  21 GGPAGSTVASRLAQKGRDVVLLEKARHPRFHI-GESLLPMNMPLFEELGIADAVATlgiPKHGAEFTIPeapdAPRTYYF 99
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKIcGGGLLPRALEELEPLGLDEPLER---PVRGARFYSP----GGKSVEL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 100 eralnDDTPASAYEVRRSEFDHLLLENSARLGVRVLEEVTVSDVALadpaNGGTQQVTARDAAgntlEFEADFVVDASGR 179
Cdd:COG0644   74 -----PPGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLR----DDGRVVVRTGDGE----EIRADYVVDADGA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 180 DTFLARRLDLKTRNAE--HNSAAIFGHFnNVPRRPGRDAGNISIYW---FQHGWIWMIPLRDGAMSVGavcfpeylktrr 254
Cdd:COG0644  141 RSLLARKLGLKRRSDEpqDYALAIKEHW-ELPPLEGVDPGAVEFFFgegAPGGYGWVFPLGDGRVSVG------------ 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 255 tkpeaflwetlklcppafdrmqgaelagpvnatGNFSYRSRQAHGPGYLLVGDAFTFVDPVFSSGVYIAMSGGFRAAEAV 334
Cdd:COG0644  208 ---------------------------------IPLGGPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAI 254

                        330       340
                 ....*....|....*....|...
gi 517709709 335 DRCLARPARAGRYLRAFERDVRR 357
Cdd:COG0644  255 AEALEGGDFSAEALAEYERRLRE 277
 
Name Accession Description Interval E-value
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
21-357 4.20e-57

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 189.79  E-value: 4.20e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  21 GGPAGSTVASRLAQKGRDVVLLEKARHPRFHI-GESLLPMNMPLFEELGIADAVATlgiPKHGAEFTIPeapdAPRTYYF 99
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKIcGGGLLPRALEELEPLGLDEPLER---PVRGARFYSP----GGKSVEL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 100 eralnDDTPASAYEVRRSEFDHLLLENSARLGVRVLEEVTVSDVALadpaNGGTQQVTARDAAgntlEFEADFVVDASGR 179
Cdd:COG0644   74 -----PPGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLR----DDGRVVVRTGDGE----EIRADYVVDADGA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 180 DTFLARRLDLKTRNAE--HNSAAIFGHFnNVPRRPGRDAGNISIYW---FQHGWIWMIPLRDGAMSVGavcfpeylktrr 254
Cdd:COG0644  141 RSLLARKLGLKRRSDEpqDYALAIKEHW-ELPPLEGVDPGAVEFFFgegAPGGYGWVFPLGDGRVSVG------------ 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 255 tkpeaflwetlklcppafdrmqgaelagpvnatGNFSYRSRQAHGPGYLLVGDAFTFVDPVFSSGVYIAMSGGFRAAEAV 334
Cdd:COG0644  208 ---------------------------------IPLGGPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAI 254

                        330       340
                 ....*....|....*....|...
gi 517709709 335 DRCLARPARAGRYLRAFERDVRR 357
Cdd:COG0644  255 AEALEGGDFSAEALAEYERRLRE 277
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 16-334 7.90e-28

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 112.03  E-value: 7.90e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPRFHI-GESLLPMNMPLFEELGIADAVatlgiPKHGAEFTIPeapdap 94
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKPcGGALSPRALEELDLPGELIVN-----LVRGARFFSP------ 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   95 rtyyFERALNDDTPA-SAYEVRRSEFDHLLLENSARLGVRVLEEVTVSDValadPANGGTQQVTARDAAGntlEFEADFV 173
Cdd:TIGR02032  72 ----NGDSVEIPIETeLAYVIDRDAFDEQLAERAQEAGAELRLGTRVLDV----EIHDDRVVVIVRGSEG---TVTAKIV 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  174 VDASGRDTFLARRLDLKTRNAEHNSAA-IFGHFNNVPRRPgrDAGNISIYW--FQHGWIWMIPLRDGAMSVG-AVCFPEY 249
Cdd:TIGR02032 141 IGADGSRSIVAKKLGLKKEPREYGVAArAEVEMPDEEVDE--DFVEVYIDRgiVPGGYGWVFPKGDGTANVGvGSRSAEE 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  250 LKTRRTKPEAFLwetlklcppafDRMQGAELAGPVNATGNF----SYRSRqAHGPGYLLVGDAFTFVDPVFSSGVYIAMS 325
Cdd:TIGR02032 219 GEDPKKYLKDFL-----------ARRPELKDAETVEVCGALipigRPDEK-LVRGNVLLVGDAAGHVNPLTGEGIYYAMR 286


                  ....*....
gi 517709709  326 GGFRAAEAV 334
Cdd:TIGR02032 287 SGDIAAEVV 295
Trp_halogenase pfam04820
Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form ...
 16-366 3.88e-16

Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form 7-chlorotryptophan. This is the first step in the biosynthesis of pyrrolnitrin, an antibiotic with broad-spectrum anti-fungal activity. Tryptophan halogenase is NADH-dependent.


Pssm-ID: 398475 [Multi-domain]  Cd Length: 457  Bit Score: 80.07  E-value: 3.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   16 VLVIGGGPAGSTVASRLA---QKGRDVVLLEKARHPRFHIGESLLPMNMPLFEELGIADAV---ATLGIPKHGAEF---- 85
Cdd:pfam04820   2 IVIVGGGTAGWMAAAALAralKGGLDVTLVESEEIGTVGVGEATIPSIRTFNRMLGIDEAEflrATQATFKLGIRFedwg 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   86 TIPEA----------------------------PDAPRTYY-----------FERALNDDTP-----ASAYEVRRSEFDH 121
Cdd:pfam04820  82 RRGERyihpfgvtghpidgvpfhhywlrlrargFAGPLDDYclpavaalagkFSPPPKDPRSglsglSYAYHFDAALYAR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  122 LLLENSARLGVRVLEEvTVSDVALAdpANGGTQQVTARDAAgntlEFEADFVVDASG-RDTFLARRLDLKTRNAEH---- 196
Cdd:pfam04820 162 FLRRNAEARGVTRVEG-KVVDVQLD--ADGFVTSLRLEDGR----EVEADLFIDCSGfRGLLIEQALKTGYEDWSDwlpc 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  197 NSA-AIFGHFNNVPRRPGRdagniSIYwFQHGWIWMIPLRDGAMSvGAVCFPEYLktrrTKPEAFlwetlklcppafdRM 275
Cdd:pfam04820 235 DRAlAVQCESVGPPEPYTR-----ATA-HDAGWRWRIPLQHRLGN-GYVYSSAHA----DDDEAL-------------AE 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  276 QGAELAGPVNATGNF----SYRSRQAHGPGYLLVGDAFTFVDPVFSSGVYIAMSggfraaeAVDRCLAR-PARAGR-YLR 349
Cdd:pfam04820 291 LLANLGGIPLAEPRLirftTGRRKQAWVKNVVALGLASGFLEPLESTSIHLIQS-------ALRRLLALfPDGGFDpAAI 363

                         410
                  ....*....|....*...
gi 517709709  350 A-FERDVRRGVRRFSWLI 366
Cdd:pfam04820 364 AeYNRRIAREYERIRDFI 381
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
13-189 7.91e-11

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 63.77  E-value: 7.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKARH----PR-FHI-GESllpmnMPLFEELGIADAVATLGIPKHG---- 82
Cdd:PRK06183  10 DTDVVIVGAGPVGLTLANLLGQYGVRVLVLERWPTlydlPRaVGIdDEA-----LRVLQAIGLADEVLPHTTPNHGmrfl 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  83 -------AEFTIPEAPDA--PRTYYFeralndDTPasayevrrsEFDHLLLENSARL-GVRVLEEVTVsdVALADPANGG 152
Cdd:PRK06183  85 dakgrclAEIARPSTGEFgwPRRNAF------HQP---------LLEAVLRAGLARFpHVRVRFGHEV--TALTQDDDGV 147

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 517709709 153 TqqVTARDAAGNTLEFEADFVVDASGRDTFLARRLDL 189
Cdd:PRK06183 148 T--VTLTDADGQRETVRARYVVGCDGANSFVRRTLGV 182
 
Name Accession Description Interval E-value
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
21-357 4.20e-57

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 189.79  E-value: 4.20e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  21 GGPAGSTVASRLAQKGRDVVLLEKARHPRFHI-GESLLPMNMPLFEELGIADAVATlgiPKHGAEFTIPeapdAPRTYYF 99
Cdd:COG0644    1 AGPAGSAAARRLARAGLSVLLLEKGSFPGDKIcGGGLLPRALEELEPLGLDEPLER---PVRGARFYSP----GGKSVEL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 100 eralnDDTPASAYEVRRSEFDHLLLENSARLGVRVLEEVTVSDVALadpaNGGTQQVTARDAAgntlEFEADFVVDASGR 179
Cdd:COG0644   74 -----PPGRGGGYVVDRARFDRWLAEQAEEAGAEVRTGTRVTDVLR----DDGRVVVRTGDGE----EIRADYVVDADGA 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 180 DTFLARRLDLKTRNAE--HNSAAIFGHFnNVPRRPGRDAGNISIYW---FQHGWIWMIPLRDGAMSVGavcfpeylktrr 254
Cdd:COG0644  141 RSLLARKLGLKRRSDEpqDYALAIKEHW-ELPPLEGVDPGAVEFFFgegAPGGYGWVFPLGDGRVSVG------------ 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 255 tkpeaflwetlklcppafdrmqgaelagpvnatGNFSYRSRQAHGPGYLLVGDAFTFVDPVFSSGVYIAMSGGFRAAEAV 334
Cdd:COG0644  208 ---------------------------------IPLGGPRPRLVGDGVLLVGDAAGFVDPLTGEGIHLAMKSGRLAAEAI 254

                        330       340
                 ....*....|....*....|...
gi 517709709 335 DRCLARPARAGRYLRAFERDVRR 357
Cdd:COG0644  255 AEALEGGDFSAEALAEYERRLRE 277
GG-red-SF TIGR02032
geranylgeranyl reductase family; This model represents a subfamily which includes ...
 16-334 7.90e-28

geranylgeranyl reductase family; This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll]


Pssm-ID: 273936 [Multi-domain]  Cd Length: 295  Bit Score: 112.03  E-value: 7.90e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPRFHI-GESLLPMNMPLFEELGIADAVatlgiPKHGAEFTIPeapdap 94
Cdd:TIGR02032   3 VVVVGAGPAGASAAYRLADKGLRVLLLEKKSFPRYKPcGGALSPRALEELDLPGELIVN-----LVRGARFFSP------ 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   95 rtyyFERALNDDTPA-SAYEVRRSEFDHLLLENSARLGVRVLEEVTVSDValadPANGGTQQVTARDAAGntlEFEADFV 173
Cdd:TIGR02032  72 ----NGDSVEIPIETeLAYVIDRDAFDEQLAERAQEAGAELRLGTRVLDV----EIHDDRVVVIVRGSEG---TVTAKIV 140

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  174 VDASGRDTFLARRLDLKTRNAEHNSAA-IFGHFNNVPRRPgrDAGNISIYW--FQHGWIWMIPLRDGAMSVG-AVCFPEY 249
Cdd:TIGR02032 141 IGADGSRSIVAKKLGLKKEPREYGVAArAEVEMPDEEVDE--DFVEVYIDRgiVPGGYGWVFPKGDGTANVGvGSRSAEE 218

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  250 LKTRRTKPEAFLwetlklcppafDRMQGAELAGPVNATGNF----SYRSRqAHGPGYLLVGDAFTFVDPVFSSGVYIAMS 325
Cdd:TIGR02032 219 GEDPKKYLKDFL-----------ARRPELKDAETVEVCGALipigRPDEK-LVRGNVLLVGDAAGHVNPLTGEGIYYAMR 286


                  ....*....
gi 517709709  326 GGFRAAEAV 334
Cdd:TIGR02032 287 SGDIAAEVV 295
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
 13-369 3.03e-19

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 88.07  E-value: 3.03e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPRFHI-GESLLPMNMPLFEELGIADAVATLGIPKHGAEFTIpeap 91
Cdd:COG0654    3 RTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRPDGrGIALSPRSLELLRRLGLWDRLLARGAPIRGIRVRD---- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  92 DAPRTYYFERALNDDTPASAYEVRRSEFDHLLLENSARLGVRVLEEVTVSDVALADpanggtQQVTARDAAGNTLefEAD 171
Cdd:COG0654   79 GSDGRVLARFDAAETGLPAGLVVPRADLERALLEAARALGVELRFGTEVTGLEQDA------DGVTVTLADGRTL--RAD 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 172 FVVDASGRDTFLARRLDLKTRnaehnsaaifghfnnvprrpGRDagnisiywFQHGWIWMiplrdgamsvgavcfpeylk 251
Cdd:COG0654  151 LVVGADGARSAVRRLLGIGFT--------------------GRD--------YPQRALWA-------------------- 182

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 252 trrtkpeAFLWETLKLCPPAFDRMQGAELAGPVNATGNFSYRSRQAHGPGYLLVGDAFTFVDPVFSSGvyiaMSGGFRAA 331
Cdd:COG0654  183 -------GVRTELRARLAAAGPRLGELLELSPRSAFPLRRRRAERWRRGRVVLLGDAAHTMHPLGGQG----ANLALRDA 251

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 517709709 332 EAVDRCLARPARAG---RYLRAFERDVRRGVRR---FSWLIYRF 369
Cdd:COG0654  252 AALAWKLAAALRGRddeAALARYERERRPRAARvqrAADALGRL 295
Trp_halogenase pfam04820
Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form ...
 16-366 3.88e-16

Tryptophan halogenase; Tryptophan halogenase catalyzes the chlorination of tryptophan to form 7-chlorotryptophan. This is the first step in the biosynthesis of pyrrolnitrin, an antibiotic with broad-spectrum anti-fungal activity. Tryptophan halogenase is NADH-dependent.


Pssm-ID: 398475 [Multi-domain]  Cd Length: 457  Bit Score: 80.07  E-value: 3.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   16 VLVIGGGPAGSTVASRLA---QKGRDVVLLEKARHPRFHIGESLLPMNMPLFEELGIADAV---ATLGIPKHGAEF---- 85
Cdd:pfam04820   2 IVIVGGGTAGWMAAAALAralKGGLDVTLVESEEIGTVGVGEATIPSIRTFNRMLGIDEAEflrATQATFKLGIRFedwg 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   86 TIPEA----------------------------PDAPRTYY-----------FERALNDDTP-----ASAYEVRRSEFDH 121
Cdd:pfam04820  82 RRGERyihpfgvtghpidgvpfhhywlrlrargFAGPLDDYclpavaalagkFSPPPKDPRSglsglSYAYHFDAALYAR 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  122 LLLENSARLGVRVLEEvTVSDVALAdpANGGTQQVTARDAAgntlEFEADFVVDASG-RDTFLARRLDLKTRNAEH---- 196
Cdd:pfam04820 162 FLRRNAEARGVTRVEG-KVVDVQLD--ADGFVTSLRLEDGR----EVEADLFIDCSGfRGLLIEQALKTGYEDWSDwlpc 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  197 NSA-AIFGHFNNVPRRPGRdagniSIYwFQHGWIWMIPLRDGAMSvGAVCFPEYLktrrTKPEAFlwetlklcppafdRM 275
Cdd:pfam04820 235 DRAlAVQCESVGPPEPYTR-----ATA-HDAGWRWRIPLQHRLGN-GYVYSSAHA----DDDEAL-------------AE 290

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  276 QGAELAGPVNATGNF----SYRSRQAHGPGYLLVGDAFTFVDPVFSSGVYIAMSggfraaeAVDRCLAR-PARAGR-YLR 349
Cdd:pfam04820 291 LLANLGGIPLAEPRLirftTGRRKQAWVKNVVALGLASGFLEPLESTSIHLIQS-------ALRRLLALfPDGGFDpAAI 363

                         410
                  ....*....|....*...
gi 517709709  350 A-FERDVRRGVRRFSWLI 366
Cdd:pfam04820 364 AeYNRRIAREYERIRDFI 381
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
 13-266 6.49e-16

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 78.52  E-value: 6.49e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEK----ARHPRFHIgesLLPMNMPLFEELGIADAVATLGIPKHGAEFTIp 88
Cdd:pfam01494   1 ETDVLIVGGGPAGLMLALLLARAGVRVVLVERhattSVLPRAHG---LNQRTMELLRQAGLEDRILAEGVPHEGMGLAF- 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   89 EAPDAPRTYYFeralnDDTPASAYEVRRSEFDHLLLENSARLGVRVLEEVTVsdvaLADPANGGTQQVTARD-AAGNTLE 167
Cdd:pfam01494  77 YNTRRRADLDF-----LTSPPRVTVYPQTELEPILVEHAEARGAQVRFGTEV----LSLEQDGDGVTAVVRDrRDGEEYT 147

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  168 FEADFVVDASGRDTFLARRLDLKTRNAEHNSAAIFGHFNNVPRRPGRDAGNISIYW--FQHGWIWMIPLRDGAMSVGAVC 245
Cdd:pfam01494 148 VRAKYLVGCDGGRSPVRKTLGIEFEGFEGVPFGSLDVLFDAPDLSDPVERAFVHYLiyAPHSRGFMVGPWRSAGRERYYV 227

                         250       260
                  ....*....|....*....|.
gi 517709709  246 FPEYLKTRRTKPEAFLWETLK 266
Cdd:pfam01494 228 QVPWDEEVEERPEEFTDEELK 248
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
13-189 7.91e-11

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 63.77  E-value: 7.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKARH----PR-FHI-GESllpmnMPLFEELGIADAVATLGIPKHG---- 82
Cdd:PRK06183  10 DTDVVIVGAGPVGLTLANLLGQYGVRVLVLERWPTlydlPRaVGIdDEA-----LRVLQAIGLADEVLPHTTPNHGmrfl 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  83 -------AEFTIPEAPDA--PRTYYFeralndDTPasayevrrsEFDHLLLENSARL-GVRVLEEVTVsdVALADPANGG 152
Cdd:PRK06183  85 dakgrclAEIARPSTGEFgwPRRNAF------HQP---------LLEAVLRAGLARFpHVRVRFGHEV--TALTQDDDGV 147

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 517709709 153 TqqVTARDAAGNTLEFEADFVVDASGRDTFLARRLDL 189
Cdd:PRK06183 148 T--VTLTDADGQRETVRARYVVGCDGANSFVRRTLGV 182
PRK06185 PRK06185
FAD-dependent oxidoreductase;
13-357 8.18e-10

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 60.26  E-value: 8.18e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKarHPRF---HIGESLLPMNMPLFEELGIADAVATLGIPK-HGAEFTIP 88
Cdd:PRK06185   6 TTDCCIVGGGPAGMMLGLLLARAGVDVTVLEK--HADFlrdFRGDTVHPSTLELMDELGLLERFLELPHQKvRTLRFEIG 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  89 EapdapRTYY---FERaLNDDTPASAyEVRRSEFDHLLLENSARL-GVRVLEEVTVSDVaLADpaNGGTQQVTARDAAGn 164
Cdd:PRK06185  84 G-----RTVTladFSR-LPTPYPYIA-MMPQWDFLDFLAEEASAYpNFTLRMGAEVTGL-IEE--GGRVTGVRARTPDG- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 165 TLEFEADFVVDASGRDTFLARRLDLKTRNAEHNSAAIFghFnNVPRRPGRDAGNISIYWFQHGWIwMIPlRDGAMSVGAV 244
Cdd:PRK06185 153 PGEIRADLVVGADGRHSRVRALAGLEVREFGAPMDVLW--F-RLPREPDDPESLMGRFGPGQGLI-MID-RGDYWQCGYV 227

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 245 cFP--EYLKTRRTKPEAFLWETLKLCPpafdrmqgaELAGPVNATGNFS---------YRSRQAHGPGYLLVGDAFTFVD 313
Cdd:PRK06185 228 -IPkgGYAALRAAGLEAFRERVAELAP---------ELADRVAELKSWDdvklldvrvDRLRRWHRPGLLCIGDAAHAMS 297

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 517709709 314 PVFSSGVYIAMSGGFRAAEAVDRCLARPARAGRYLRAFERdvRR 357
Cdd:PRK06185 298 PVGGVGINLAIQDAVAAANILAEPLRRGRVSDRDLAAVQR--RR 339
COG1233 COG1233
Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and ...
 16-116 5.70e-08

Phytoene dehydrogenase-related protein [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440846 [Multi-domain]  Cd Length: 491  Bit Score: 54.86  E-value: 5.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP------------RFHIGESLLPMNM---PLFEELGIADAVATLGIP- 79
Cdd:COG1233    6 VVVIGAGIGGLAAAALLARAGYRVTVLEKNDTPggrartferpgfRFDVGPSVLTMPGvleRLFRELGLEDYLELVPLDp 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 517709709  80 ------KHGAEFTIPEAPDAprtyyFERALNDDTPASAYEVRR 116
Cdd:COG1233   86 ayrvpfPDGRALDLPRDLER-----TAAELERLFPGDAEAYRR 123
PRK06126 PRK06126
hypothetical protein; Provisional
 13-187 6.58e-08

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 54.61  E-value: 6.58e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPRFHIGESLLPM-NMPLFEELGIADAVATLGIPKH---------- 81
Cdd:PRK06126   7 ETPVLIVGGGPVGLALALDLGRRGVDSILVERKDGTAFNPKANTTSArSMEHFRRLGIADEVRSAGLPVDyptdiayftr 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  82 --GAE---FTIPEAPDAPrTYYFERALNDDTPASAYEVRRSEFDHLLLENSARL-GVRVLEEVTVSDValADPANGGTqq 155
Cdd:PRK06126  87 ltGYElarFRLPSAREAI-TPVGGPDGSWPSPELPHRIPQKYLEPILLEHAAAQpGVTLRYGHRLTDF--EQDADGVT-- 161

                        170       180       190
                 ....*....|....*....|....*....|...
gi 517709709 156 VTARDAA-GNTLEFEADFVVDASGRDTFLARRL 187
Cdd:PRK06126 162 ATVEDLDgGESLTIRADYLVGCDGARSAVRRSL 194
PLN02985 PLN02985
squalene monooxygenase
 3-325 9.88e-07

squalene monooxygenase


Pssm-ID: 178566 [Multi-domain]  Cd Length: 514  Bit Score: 51.06  E-value: 9.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   3 QAVENAGTDGRCQVLVIGGGPAGSTVASRLAQKGRDVVLLEK-ARHPRFHIGESLLPMNMPLFEELGIADAV-------A 74
Cdd:PLN02985  33 DAVAEERKDGATDVIIVGAGVGGSALAYALAKDGRRVHVIERdLREPERMMGEFMQPGGRFMLSKLGLEDCLegidaqkA 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  75 T-LGIPKHGAEFTIPEAPDaprtyyferalNDDTP--ASAYEVRRSEFDHLLLENSARLGVRVLEEVTVSDVAladPANG 151
Cdd:PLN02985 113 TgMAVYKDGKEAVAPFPVD-----------NNNFPyePSARSFHNGRFVQRLRQKASSLPNVRLEEGTVKSLI---EEKG 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 152 GTQQVTARDAAGNTLEFEADFVVDASGRDTFLARRLDlktrnaeHNSAAIFGHFNNVPRRPGR--DAGNISIYWFQHGWI 229
Cdd:PLN02985 179 VIKGVTYKNSAGEETTALAPLTVVCDGCYSNLRRSLN-------DNNAEVLSYQVGYISKNCRleEPEKLHLIMSKPSFT 251

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 230 WMIPLRDGAMSVGAVCFPEYLKT-RRTKPEAFLWETLKLCPPAFDR---MQGAELAGPVNATGNFSYRSRQAHGPGYLLV 305
Cdd:PLN02985 252 MLYQISSTDVRCVFEVLPDNIPSiANGEMSTFVKNTIAPQVPPKLRkifLKGIDEGAHIKVVPTKRMSATLSDKKGVIVL 331

                        330       340
                 ....*....|....*....|
gi 517709709 306 GDAFTFVDPVFSSGVYIAMS 325
Cdd:PLN02985 332 GDAFNMRHPAIASGMMVLLS 351
NAD_binding_8 pfam13450
NAD(P)-binding Rossmann-like domain;
18-48 1.07e-06

NAD(P)-binding Rossmann-like domain;


Pssm-ID: 433218 [Multi-domain]  Cd Length: 67  Bit Score: 45.99  E-value: 1.07e-06
                          10        20        30
                  ....*....|....*....|....*....|.
gi 517709709   18 VIGGGPAGSTVASRLAQKGRDVVLLEKARHP 48
Cdd:pfam13450   1 IVGAGLAGLVAAALLAKRGFRVLVLEKRDRL 31
PRK07538 PRK07538
hypothetical protein; Provisional
 15-178 1.46e-06

hypothetical protein; Provisional


Pssm-ID: 236046 [Multi-domain]  Cd Length: 413  Bit Score: 50.28  E-value: 1.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPR-FHIGESLLPMNMPLFEELGIADAVATLGIP--------KHGAEF 85
Cdd:PRK07538   2 KVLIAGGGIGGLTLALTLHQRGIEVVVFEAAPELRpLGVGINLLPHAVRELAELGLLDALDAIGIRtrelayfnRHGQRI 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  86 tipeapdaprtyYFE-RALNDDTPASAYEVRRSEFdHLLLENSA--RLGVRVLeeVTVSDVALADPANGGTQQVTARDAA 162
Cdd:PRK07538  82 ------------WSEpRGLAAGYDWPQYSIHRGEL-QMLLLDAVreRLGPDAV--RTGHRVVGFEQDADVTVVFLGDRAG 146

                        170
                 ....*....|....*.
gi 517709709 163 GNTLEFEADFVVDASG 178
Cdd:PRK07538 147 GDLVSVRGDVLIGADG 162
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 13-71 4.42e-06

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 48.68  E-value: 4.42e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP------------RFHIG-ESLLPMN---MPLFEELGIAD 71
Cdd:COG1232    1 MKRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVgglirtvevdgfRIDRGpHSFLTRDpevLELLRELGLGD 75
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 14-46 7.32e-06

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 48.16  E-value: 7.32e-06
                         10        20        30
                 ....*....|....*....|....*....|...
gi 517709709  14 CQVLVIGGGPAGSTVASRLAQKGRDVVLLEKAR 46
Cdd:COG1249    4 YDLVVIGAGPGGYVAAIRAAQLGLKVALVEKGR 36
PTZ00367 PTZ00367
squalene epoxidase; Provisional
 16-82 1.39e-05

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 47.54  E-value: 1.39e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKA--RHPRFHIGESLLPMNMPLFEELGIADAVATLGIPKHG 82
Cdd:PTZ00367  36 VIIVGGSIAGPVLAKALSKQGRKVLMLERDlfSKPDRIVGELLQPGGVNALKELGMEECAEGIGMPCFG 104
FAD_oxidored pfam12831
FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases ...
 16-178 2.02e-05

FAD dependent oxidoreductase; This family of proteins contains FAD dependent oxidoreductases and related proteins.


Pssm-ID: 432816 [Multi-domain]  Cd Length: 420  Bit Score: 46.83  E-value: 2.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   16 VLVIGGGPAGSTVASRLAQKGRDVVLLEkarhPRFHIG-----ESLLPMNMPLFEEL----GIADAVaTLGIPKHGAEFT 86
Cdd:pfam12831   2 VVVVGGGPAGVAAAIAAARAGAKVLLVE----RRGFLGgmltsGLVGPDMGFYLNKEqvvgGIAREF-RQRLRARGGLPG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709   87 IPEAPDAPRTYYFERALnddtpasayEVrrseFDHLLLENsarlGVRVLEEVTVSDVALADpanGGTQQVTARDAAGnTL 166
Cdd:pfam12831  77 PYGLRGGWVPFDPEVAK---------AV----LDEMLAEA----GVTVLLHTRVVGVVKEG---GRITGVTVETKGG-RI 135

                         170
                  ....*....|..
gi 517709709  167 EFEADFVVDASG 178
Cdd:pfam12831 136 TIRAKVFIDATG 147
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
16-44 3.14e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 46.39  E-value: 3.14e-05
                         10        20
                 ....*....|....*....|....*....
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEK 44
Cdd:COG1148  143 ALVIGGGIAGMTAALELAEQGYEVYLVEK 171
DadA COG0665
Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];
13-190 3.47e-05

Glycine/D-amino acid oxidase (deaminating) [Amino acid transport and metabolism];


Pssm-ID: 440429 [Multi-domain]  Cd Length: 364  Bit Score: 45.67  E-value: 3.47e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKAR---------------HPRFHIGESLLPMNM-------PLFEELGIA 70
Cdd:COG0665    2 TADVVVIGGGIAGLSTAYHLARRGLDVTVLERGRpgsgasgrnagqlrpGLAALADRALVRLARealdlwrELAAELGID 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  71 DAVATLGI--------------------PKHGAEFTIPEAPDAPRtyyFERALNDDTPASAYEVRRSE-FDHL-----LL 124
Cdd:COG0665   82 CDFRRTGVlylarteaelaalraeaealRALGLPVELLDAAELRE---REPGLGSPDYAGGLYDPDDGhVDPAklvraLA 158

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 517709709 125 ENSARLGVRVLEEVTVSDValaDPANGGTQQVTARDAagntlEFEADFVVDASGRDTF-LARRLDLK 190
Cdd:COG0665  159 RAARAAGVRIREGTPVTGL---EREGGRVTGVRTERG-----TVRADAVVLAAGAWSArLLPMLGLR 217
HI0933_like pfam03486
HI0933-like protein;
14-48 6.46e-05

HI0933-like protein;


Pssm-ID: 427330 [Multi-domain]  Cd Length: 406  Bit Score: 44.88  E-value: 6.46e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 517709709   14 CQVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP 48
Cdd:pfam03486   1 FDVIVIGGGAAGLMAAISAAKRGRRVLLIEKGKKL 35
YhiN COG2081
Predicted flavoprotein YhiN [General function prediction only];
17-48 9.25e-05

Predicted flavoprotein YhiN [General function prediction only];


Pssm-ID: 441684 [Multi-domain]  Cd Length: 402  Bit Score: 44.66  E-value: 9.25e-05
                         10        20        30
                 ....*....|....*....|....*....|..
gi 517709709  17 LVIGGGPAGSTVASRLAQKGRDVVLLEKARHP 48
Cdd:COG2081    1 IVIGAGAAGLMAAITAAERGARVLLLEKNPKV 32
PRK07233 PRK07233
hypothetical protein; Provisional
 16-73 1.07e-04

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 44.49  E-value: 1.07e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP---------------RF--HIGESLLPMnMPLFEELGIADAV 73
Cdd:PRK07233   2 IAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLgglaasfefgglpieRFyhHIFKSDEAL-LELLDELGLEDKL 75
PRK09126 PRK09126
FAD-dependent hydroxylase;
13-360 1.17e-04

FAD-dependent hydroxylase;


Pssm-ID: 236385 [Multi-domain]  Cd Length: 392  Bit Score: 44.16  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEkaRHPRFHIGEsllpmnmPLFEELGIADAVATLGIPKH-GAEFTIPEAP 91
Cdd:PRK09126   3 HSDIVVVGAGPAGLSFARSLAGSGLKVTLIE--RQPLAALAD-------PAFDGREIALTHASREILQRlGAWDRIPEDE 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  92 DAP----RTY--YFERALNDDTPASA----------YEVRRSEFDhlllENSARLGVRVLEEVTVSDValadpaNGGTQQ 155
Cdd:PRK09126  74 ISPlrdaKVLngRSPFALTFDARGRGadalgylvpnHLIRRAAYE----AVSQQDGIELLTGTRVTAV------RTDDDG 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 156 VTARDAAGNTLefEADFVVDASGRdtFLArrldlkTRNAEHNSAAI--FGHFNNVPR-RPGRDAGNISIYWFQHGW-IWM 231
Cdd:PRK09126 144 AQVTLANGRRL--TARLLVAADSR--FSA------TRRQLGIGADMhdFGRTMLVCRmRHELPHHHTAWEWFGYGQtLAL 213

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709 232 IPLRDGAMSVGAVCFPEYLKT-RRTKPEAFLWETLKLCPPAFDRMQ--GAELAGPVNATgnfsyRSRQAHGPGYLLVGDA 308
Cdd:PRK09126 214 LPLNGHLSSLVLTLPPDQIEAlLALDPEAFAAEVTARFKGRLGAMRlvSSRHAYPLVAV-----YAHRFVAKRFALIGDA 288

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 517709709 309 FTFVDPVFSSGVYIAMSGGFRAAEAVDRCLARPARAGRY--LRAFERDVRRGVR 360
Cdd:PRK09126 289 AVGMHPVTAHGFNLGLKGQDILARLILAAARRGQDIGAAslLERYERKHRLATR 342
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 15-47 1.64e-04

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 43.46  E-value: 1.64e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 517709709   15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEKARH 47
Cdd:pfam07992   2 DVVVIGGGPAGLAAALTLAQLGGKVTLIEDEGT 34
DAO pfam01266
FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: ...
 16-51 1.77e-04

FAD dependent oxidoreductase; This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.


Pssm-ID: 426168 [Multi-domain]  Cd Length: 339  Bit Score: 43.54  E-value: 1.77e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 517709709   16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPRFH 51
Cdd:pfam01266   2 VVVIGGGIVGLSTAYELARRGLSVTLLERGDDPGSG 37
PRK13800 PRK13800
fumarate reductase/succinate dehydrogenase flavoprotein subunit;
14-61 2.01e-04

fumarate reductase/succinate dehydrogenase flavoprotein subunit;


Pssm-ID: 237512 [Multi-domain]  Cd Length: 897  Bit Score: 44.07  E-value: 2.01e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 517709709  14 CQVLVIGGGPAGSTVASRLAQKGRDVVLLEKArHPRfHIGEslLPMNM 61
Cdd:PRK13800  14 CDVLVIGGGTAGTMAALTAAEHGANVLLLEKA-HVR-HSGA--LAMGM 57
SdhA COG1053
Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and ...
 11-197 2.15e-04

Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, flavoprotein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440673 [Multi-domain]  Cd Length: 443  Bit Score: 43.28  E-value: 2.15e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  11 DGRCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPR---------FHIGESllPMNMPLFE---ELGIADAVatlgi 78
Cdd:COG1053    1 DHEYDVVVVGSGGAGLRAALEAAEAGLKVLVLEKVPPRGghtaaaqggINAAGT--NVQKAAGEdspEEHFYDTV----- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  79 pkHGAEFTIPEAP------DAPRTYY--------FERALNDDTPAS-AYEVRRS---------EFDHLLLENSARLGVRV 134
Cdd:COG1053   74 --KGGDGLADQDLvealaeEAPEAIDwleaqgvpFSRTPDGRLPQFgGHSVGRTcyagdgtghALLATLYQAALRLGVEI 151

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517709709 135 LEEVTVSDVALADpanGGTQQVTARDAAGNTLEFEADFVVDASG--------RDTFLARRLDLKTRNAEHN 197
Cdd:COG1053  152 FTETEVLDLIVDD---GRVVGVVARDRTGEIVRIRAKAVVLATGgfgrnyemRAEYLPEAEGALSTNAPGN 219
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 16-47 2.21e-04

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 43.24  E-value: 2.21e-04
                         10        20        30
                 ....*....|....*....|....*....|..
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEkARH 47
Cdd:PRK11749 143 VAVIGAGPAGLTAAHRLARKGYDVTIFE-ARD 173
BetA COG2303
Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General ...
 16-52 2.30e-04

Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only]; Choline dehydrogenase or related flavoprotein is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 441878 [Multi-domain]  Cd Length: 531  Bit Score: 43.66  E-value: 2.30e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 517709709  16 VLVIGGGPAGSTVASRLAQ-KGRDVVLLE---KARHPRFHI 52
Cdd:COG2303    7 YVIVGAGSAGCVLANRLSEdAGLRVLLLEaggRDDDPLIRM 47
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 16-44 2.83e-04

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 43.24  E-value: 2.83e-04
                         10        20
                 ....*....|....*....|....*....
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEK 44
Cdd:PRK06292   6 VIVIGAGPAGYVAARRAAKLGKKVALIEK 34
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 16-48 3.01e-04

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 42.81  E-value: 3.01e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP 48
Cdd:COG0493  124 VAVVGSGPAGLAAAYQLARAGHEVTVFEALDKP 156
PRK07208 PRK07208
hypothetical protein; Provisional
 15-47 3.22e-04

hypothetical protein; Provisional


Pssm-ID: 235967 [Multi-domain]  Cd Length: 479  Bit Score: 42.95  E-value: 3.22e-04
                         10        20        30
                 ....*....|....*....|....*....|...
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEKARH 47
Cdd:PRK07208   6 SVVIIGAGPAGLTAAYELLKRGYPVTVLEADPV 38
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 13-46 4.19e-04

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 42.54  E-value: 4.19e-04
                         10        20        30
                 ....*....|....*....|....*....|....
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKAR 46
Cdd:COG2072    6 HVDVVVIGAGQAGLAAAYHLRRAGIDFVVLEKAD 39
PRK08243 PRK08243
4-hydroxybenzoate 3-monooxygenase; Validated
 13-85 7.17e-04

4-hydroxybenzoate 3-monooxygenase; Validated


Pssm-ID: 236198 [Multi-domain]  Cd Length: 392  Bit Score: 41.71  E-value: 7.17e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517709709  13 RCQVLVIGGGPAGSTVASRLAQKGRDVVLLEkaRHPRFHIgES------LLPMNMPLFEELGIADAVATLGIPKHGAEF 85
Cdd:PRK08243   2 RTQVAIIGAGPAGLLLGQLLHLAGIDSVVLE--RRSREYV-EGriragvLEQGTVDLLREAGVGERMDREGLVHDGIEL 77
PRK08132 PRK08132
FAD-dependent oxidoreductase; Provisional
 8-45 7.36e-04

FAD-dependent oxidoreductase; Provisional


Pssm-ID: 236158 [Multi-domain]  Cd Length: 547  Bit Score: 41.78  E-value: 7.36e-04
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 517709709   8 AGTDGRCQVLVIGGGPAGSTVASRLAQKGRDVVLLEKA 45
Cdd:PRK08132  18 ADDPARHPVVVVGAGPVGLALAIDLAQQGVPVVLLDDD 55
PRK08244 PRK08244
monooxygenase;
15-178 8.34e-04

monooxygenase;


Pssm-ID: 236199 [Multi-domain]  Cd Length: 493  Bit Score: 41.65  E-value: 8.34e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP-RFHIGESLLPMNMPLFEELGIADAVATLGIPKHGAEFTipeapdA 93
Cdd:PRK08244   4 EVIIIGGGPVGLMLASELALAGVKTCVIERLKETvPYSKALTLHPRTLEILDMRGLLERFLEKGRKLPSGHFA------G 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  94 PRTYYFERALNDDTPASAYeVRRSEFDHLLLENSARLGVRVLEEVTVsdvaLADPANGGTQQVTARDAAGNTLeFEADFV 173
Cdd:PRK08244  78 LDTRLDFSALDTSSNYTLF-LPQAETEKVLEEHARSLGVEIFRGAEV----LAVRQDGDGVEVVVRGPDGLRT-LTSSYV 151


                 ....*
gi 517709709 174 VDASG 178
Cdd:PRK08244 152 VGADG 156
PRK07494 PRK07494
UbiH/UbiF family hydroxylase;
14-74 1.45e-03

UbiH/UbiF family hydroxylase;


Pssm-ID: 181001 [Multi-domain]  Cd Length: 388  Bit Score: 40.66  E-value: 1.45e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 517709709  14 CQVLVIGGGPAGSTVASRLAQKGRDVVLLEkarhPRFHIGE----SLLPMNMPLFEELGIADAVA 74
Cdd:PRK07494   8 TDIAVIGGGPAGLAAAIALARAGASVALVA----PEPPYADlrttALLGPSIRFLERLGLWARLA 68
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 16-53 1.70e-03

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 40.53  E-value: 1.70e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEkaRHPRfhIG 53
Cdd:PRK12810 146 VAVVGSGPAGLAAADQLARAGHKVTVFE--RADR--IG 179
PRK12921 PRK12921
oxidoreductase;
15-47 1.86e-03

oxidoreductase;


Pssm-ID: 183829 [Multi-domain]  Cd Length: 305  Bit Score: 40.23  E-value: 1.86e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEKARH 47
Cdd:PRK12921   2 RIAVVGAGAVGGTFGGRLLEAGRDVTFLVRPKR 34
mnmC PRK01747
bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent ...
 16-45 2.60e-03

bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC;


Pssm-ID: 234978 [Multi-domain]  Cd Length: 662  Bit Score: 40.21  E-value: 2.60e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKA 45
Cdd:PRK01747 263 AAIIGGGIAGAALALALARRGWQVTLYEAD 292
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
16-73 2.62e-03

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 40.02  E-value: 2.62e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARhprfHIGE-----SLLPMNMPLFEELGIADAV 73
Cdd:PRK08163   7 VLIVGGGIGGLAAALALARQGIKVKLLEQAA----EIGEigagiQLGPNAFSALDALGVGEAA 65
COG3349 COG3349
Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function ...
 16-48 2.89e-03

Uncharacterized protein, contains NAD-binding domain and a Fe-S cluster [General function prediction only];


Pssm-ID: 442577 [Multi-domain]  Cd Length: 445  Bit Score: 39.84  E-value: 2.89e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP 48
Cdd:COG3349    6 VVVVGGGLAGLAAAVELAEAGFRVTLLEARPRL 38
TIGR00275 TIGR00275
flavoprotein, HI0933 family; The model when searched with a partial length search brings in ...
 17-46 2.94e-03

flavoprotein, HI0933 family; The model when searched with a partial length search brings in proteins with a dinucleotide-binding motif (Rossman fold) over the initial 40 residues of the model, including oxidoreductases and dehydrogenases. Partially characterized members include an FAD-binding protein from Bacillus cereus and flavoprotein HI0933 from Haemophilus influenzae. [Unknown function, Enzymes of unknown specificity]


Pssm-ID: 272992 [Multi-domain]  Cd Length: 400  Bit Score: 39.89  E-value: 2.94e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 517709709   17 LVIGGGPAGSTVASRLAQKGRDVVLLEKAR 46
Cdd:TIGR00275   1 IIIGGGAAGLMAAITAARAGLSVLLLEKNK 30
lipoamide_DH TIGR01350
dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a ...
 16-44 3.24e-03

dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.


Pssm-ID: 273568 [Multi-domain]  Cd Length: 460  Bit Score: 39.55  E-value: 3.24e-03
                          10        20
                  ....*....|....*....|....*....
gi 517709709   16 VLVIGGGPAGSTVASRLAQKGRDVVLLEK 44
Cdd:TIGR01350   4 VIVIGGGPGGYVAAIRAAQLGLKVALVEK 32
FAD_binding_2 pfam00890
FAD binding domain; This family includes members that bind FAD. This family includes the ...
 16-45 3.25e-03

FAD binding domain; This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.


Pssm-ID: 395718 [Multi-domain]  Cd Length: 398  Bit Score: 39.58  E-value: 3.25e-03
                          10        20        30
                  ....*....|....*....|....*....|
gi 517709709   16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKA 45
Cdd:pfam00890   2 VLVIGGGLAGLAAALAAAEAGLKVAVVEKG 31
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
16-46 3.69e-03

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 39.52  E-value: 3.69e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEkAR 46
Cdd:COG1231   10 VVIVGAGLAGLAAARELRKAGLDVTVLE-AR 39
PLN00093 PLN00093
geranylgeranyl diphosphate reductase; Provisional
 15-44 3.89e-03

geranylgeranyl diphosphate reductase; Provisional


Pssm-ID: 177713 [Multi-domain]  Cd Length: 450  Bit Score: 39.35  E-value: 3.89e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEK 44
Cdd:PLN00093  41 RVAVIGGGPAGACAAETLAKGGIETFLIER 70
carotene-cycl TIGR01790
lycopene cyclase family protein; This family includes lycopene beta and epsilion cyclases ...
 16-46 4.15e-03

lycopene cyclase family protein; This family includes lycopene beta and epsilion cyclases (which form beta and delta carotene, respectively) from bacteria and plants as well as the plant capsanthin/capsorubin and neoxanthin cyclases which appear to have evolved from the plant lycopene cyclases. The plant lycopene epsilon cyclases also transform neurosporene to alpha zeacarotene.


Pssm-ID: 130850 [Multi-domain]  Cd Length: 388  Bit Score: 39.34  E-value: 4.15e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 517709709   16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKAR 46
Cdd:TIGR01790   2 LAVIGGGPAGLAIALELARPGLRVQLIEPHP 32
PRK12831 PRK12831
putative oxidoreductase; Provisional
 15-88 6.55e-03

putative oxidoreductase; Provisional


Pssm-ID: 183780 [Multi-domain]  Cd Length: 464  Bit Score: 38.85  E-value: 6.55e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVllekarhprfhigesllpmnmpLFEELGIADAVATLGIPkhgaEFTIP 88
Cdd:PRK12831 142 KVAVIGSGPAGLTCAGDLAKMGYDVT----------------------IFEALHEPGGVLVYGIP----EFRLP 189
PRK06847 PRK06847
hypothetical protein; Provisional
 15-178 7.45e-03

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 38.32  E-value: 7.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHPR-FHIGESLLPMNMPLFEELGIADAVATLGIPKHGAEFTIP----- 88
Cdd:PRK06847   6 KVLIVGGGIGGLSAAIALRRAGIAVDLVEIDPEWRvYGAGITLQGNALRALRELGVLDECLEAGFGFDGVDLFDPdgtll 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517709709  89 -EAPDaprtyyfERALNDDTPASAyEVRRSEFDHLLLENSARLGVRVLEEVTVsdVALADPANGgtqqVTARDAAGNTLE 167
Cdd:PRK06847  86 aELPT-------PRLAGDDLPGGG-GIMRPALARILADAARAAGADVRLGTTV--TAIEQDDDG----VTVTFSDGTTGR 151

                        170
                 ....*....|.
gi 517709709 168 FeaDFVVDASG 178
Cdd:PRK06847 152 Y--DLVVGADG 160
PRK12778 PRK12778
bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate ...
 15-78 7.54e-03

bifunctional dihydroorotate dehydrogenase B NAD binding subunit/NADPH-dependent glutamate synthase;


Pssm-ID: 237200 [Multi-domain]  Cd Length: 752  Bit Score: 38.95  E-value: 7.54e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP----RFHIGESLLPMNMpLFEELgiaDAVATLGI 78
Cdd:PRK12778 433 KVAVIGSGPAGLSFAGDLAKRGYDVTVFEALHEIggvlKYGIPEFRLPKKI-VDVEI---ENLKKLGV 496
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 16-52 7.83e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 38.70  E-value: 7.83e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|.
gi 517709709  16 VLVIGGGPAGSTVASRLAQKGRDVVLLEKARHP----RFHI 52
Cdd:PRK12771 140 VAVIGGGPAGLSAAYHLRRMGHAVTIFEAGPKLggmmRYGI 180
TrkA COG0569
Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion ...
 15-44 7.89e-03

Trk/Ktr K+ transport system regulatory component TrkA/KtrA/KtrC, RCK domain [Inorganic ion transport and metabolism, Signal transduction mechanisms];


Pssm-ID: 440335 [Multi-domain]  Cd Length: 296  Bit Score: 38.12  E-value: 7.89e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 517709709  15 QVLVIGGGPAGSTVASRLAQKGRDVVLLEK 44
Cdd:COG0569   97 HVIIIGAGRVGRSLARELEEEGHDVVVIDK 126
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH