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Conserved domains on  [gi|517994778|ref|WP_019164986|]
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peptidylprolyl isomerase [Staphylococcus delphini]

Protein Classification

peptidylprolyl isomerase( domain architecture ID 1000880)

peptidylprolyl isomerase plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins, and it functions as a peptidyl-prolyl cis-trans isomerase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides

EC:  5.2.1.8
Gene Ontology:  GO:0003755|GO:0006457
PubMed:  10228556

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 144-277 3.44e-25

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 98.49  E-value: 3.44e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 144 KASHILIKVKQDKDDKEglsdkdAKKKIEEIKEKLDKNpKDFDKIAKEESMD-STKDKNGSLGYVIKGQMVKPFEEALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDpGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 223 LKEGQISDVVKTEYGYHII-----RADKEDDFDKEKSKLKEKIIQNKLQEDPKILTDAYK 277
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIkvedrRPAETPPFEEVKQQIRQELFQQALEAWLEELRKKAK 142
prsA super family cl35263
peptidylprolyl isomerase; Provisional
 1-298 1.87e-24

peptidylprolyl isomerase; Provisional


The actual alignment was detected with superfamily member PRK04405:

Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 100.63  E-value: 1.87e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778   1 MKKGIQKLFIPIT--ASAVLLGACGndaptSKDQTLISSKAGDVKVEDVLKEIGNDQIASQSF-KVLLDKILEKKYGDKV 77
Cdd:PRK04405   1 MKKKMKKWALAAAsaGLALSLAGCS-----SNQATVATYSGGKITQSQYYKEMKQSSAGKTVLaNMIIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  78 DQKQIDKETDEEIEKYGgkKQFENLLKQQGMTIDDYKKQRKLVSYQKELLNEKVKVSDKEIKENTKK------ASHILIk 151
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSyqpkvtVQHILV- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 152 vkqdkddkeglSDKDAKKKIEEIKekldKNPKDFDKIAKEESMDS-TKDKNGSLGYV--IKGQMVKPFEEALFKLKEGQI 228
Cdd:PRK04405 153 -----------SKKSTAETVIKKL----KDGKDFAKLAKKYSTDTaTKNKGGKLSAFdsTDTTLDSTFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517994778 229 SDV-VKTEYGYHIIRADK---EDDFDKEKSKLKEKIIqNKLQEDPKILTDAYKDLLDEYNVDYKDRDVKKAIED 298
Cdd:PRK04405 218 TTTpVKTTYGYEVIKMIKhpaKGTFSDHKKALTKQIY-AKWASDSSVMQRVISKVLKKANVSIKDKDLKDALSS 290
 
Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 144-277 3.44e-25

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 98.49  E-value: 3.44e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 144 KASHILIKVKQDKDDKEglsdkdAKKKIEEIKEKLDKNpKDFDKIAKEESMD-STKDKNGSLGYVIKGQMVKPFEEALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDpGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 223 LKEGQISDVVKTEYGYHII-----RADKEDDFDKEKSKLKEKIIQNKLQEDPKILTDAYK 277
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIkvedrRPAETPPFEEVKQQIRQELFQQALEAWLEELRKKAK 142
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-298 1.87e-24

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 100.63  E-value: 1.87e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778   1 MKKGIQKLFIPIT--ASAVLLGACGndaptSKDQTLISSKAGDVKVEDVLKEIGNDQIASQSF-KVLLDKILEKKYGDKV 77
Cdd:PRK04405   1 MKKKMKKWALAAAsaGLALSLAGCS-----SNQATVATYSGGKITQSQYYKEMKQSSAGKTVLaNMIIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  78 DQKQIDKETDEEIEKYGgkKQFENLLKQQGMTIDDYKKQRKLVSYQKELLNEKVKVSDKEIKENTKK------ASHILIk 151
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSyqpkvtVQHILV- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 152 vkqdkddkeglSDKDAKKKIEEIKekldKNPKDFDKIAKEESMDS-TKDKNGSLGYV--IKGQMVKPFEEALFKLKEGQI 228
Cdd:PRK04405 153 -----------SKKSTAETVIKKL----KDGKDFAKLAKKYSTDTaTKNKGGKLSAFdsTDTTLDSTFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517994778 229 SDV-VKTEYGYHIIRADK---EDDFDKEKSKLKEKIIqNKLQEDPKILTDAYKDLLDEYNVDYKDRDVKKAIED 298
Cdd:PRK04405 218 TTTpVKTTYGYEVIKMIKhpaKGTFSDHKKALTKQIY-AKWASDSSVMQRVISKVLKKANVSIKDKDLKDALSS 290
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-245 1.36e-19

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 81.96  E-value: 1.36e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  147 HILIKVKqdkdDKEGLSDKDAKKKIEEIKEKLDKNPKDFDKIAKEESMD-STKDKNGSLGYVIKGQMVKPFEEALFKLKE 225
Cdd:pfam00639   1 HILIKTP----EASERDRAEAKAKAEEILEQLKSGEDSFAELARKYSDDcPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 517994778  226 GQISDVVKTEYGYHIIRADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 144-241 7.70e-18

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 77.76  E-value: 7.70e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 144 KASHILIK-------VKQDKDDKEGLSDKDAKKKIEEIKEKLDKNPKDFDKIAKEESMDSTKDKNGSLGYVIKGQMVKPF 216
Cdd:PTZ00356   7 RAAHLLIKhtgsrnpVSRRTGKPVTRSKEEAIKELAKWREQIVSGEKTFEEIARQRSDCGSAAKGGDLGFFGRGQMQKPF 86

                         90       100
                 ....*....|....*....|....*
gi 517994778 217 EEALFKLKEGQISDVVKTEYGYHII 241
Cdd:PTZ00356  87 EDAAFALKVGEISDIVHTDSGVHII 111
 
Name Accession Description Interval E-value
SurA COG0760
Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, ...
 144-277 3.44e-25

Peptidyl-prolyl isomerase, parvulin family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440523 [Multi-domain]  Cd Length: 143  Bit Score: 98.49  E-value: 3.44e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 144 KASHILIKVKQDKDDKEglsdkdAKKKIEEIKEKLDKNpKDFDKIAKEESMD-STKDKNGSLGYVIKGQMVKPFEEALFK 222
Cdd:COG0760   10 RASHILVKVPPSEDRAK------AEAKAEELLAQLKAG-ADFAELAKEYSQDpGSAANGGDLGWFSRGQLVPEFEEAAFA 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 223 LKEGQISDVVKTEYGYHII-----RADKEDDFDKEKSKLKEKIIQNKLQEDPKILTDAYK 277
Cdd:COG0760   83 LKPGEISGPVKTQFGYHIIkvedrRPAETPPFEEVKQQIRQELFQQALEAWLEELRKKAK 142
prsA PRK04405
peptidylprolyl isomerase; Provisional
 1-298 1.87e-24

peptidylprolyl isomerase; Provisional


Pssm-ID: 235295 [Multi-domain]  Cd Length: 298  Bit Score: 100.63  E-value: 1.87e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778   1 MKKGIQKLFIPIT--ASAVLLGACGndaptSKDQTLISSKAGDVKVEDVLKEIGNDQIASQSF-KVLLDKILEKKYGDKV 77
Cdd:PRK04405   1 MKKKMKKWALAAAsaGLALSLAGCS-----SNQATVATYSGGKITQSQYYKEMKQSSAGKTVLaNMIIYRALEKQYGKKV 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  78 DQKQIDKETDEEIEKYGgkKQFENLLKQQGMTIDDYKKQRKLVSYQKELLNEKVKVSDKEIKENTKK------ASHILIk 151
Cdd:PRK04405  76 STKKVDKQYNSYKKQYG--SSFDSVLSQNGMTTSSFKQNLRTNLLSEAALKKLKKVTNSQLKKAWKSyqpkvtVQHILV- 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 152 vkqdkddkeglSDKDAKKKIEEIKekldKNPKDFDKIAKEESMDS-TKDKNGSLGYV--IKGQMVKPFEEALFKLKEGQI 228
Cdd:PRK04405 153 -----------SKKSTAETVIKKL----KDGKDFAKLAKKYSTDTaTKNKGGKLSAFdsTDTTLDSTFKTAAFKLKNGEY 217

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517994778 229 SDV-VKTEYGYHIIRADK---EDDFDKEKSKLKEKIIqNKLQEDPKILTDAYKDLLDEYNVDYKDRDVKKAIED 298
Cdd:PRK04405 218 TTTpVKTTYGYEVIKMIKhpaKGTFSDHKKALTKQIY-AKWASDSSVMQRVISKVLKKANVSIKDKDLKDALSS 290
prsA PRK03095
peptidylprolyl isomerase PrsA;
15-298 3.54e-24

peptidylprolyl isomerase PrsA;


Pssm-ID: 179537 [Multi-domain]  Cd Length: 287  Bit Score: 99.68  E-value: 3.54e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  15 SAVLLGACGndapTSKDQTLISSKAGDVKVEDVLKEIGNDQIASQSFKVLLDKILEKKYgdKVDQKQIDKETDEEIEKYG 94
Cdd:PRK03095  12 SVIALSACG----TSSSDKIVTSKAGDITKDEFYEQMKTQAGKQVLNNMVMEKVLIKNY--KVEDKEVDKKYDEMKKQYG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  95 gkKQFENLLKQQGMTIDDYKKQRKLVSYQKELLNEKVkvSDKEIKENTK---KASHILIKVKQD-KDDKEGLSDKdakkk 170
Cdd:PRK03095  86 --DQFDTLLKQQGIKEETLKTGVRAQLAQEKAIEKTI--TDKELKDNYKpeiKASHILVKDEATaKKVKEELGQG----- 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 171 ieeikekldknpKDFDKIAKEESMDS-TKDKNGSLGYVIKGQMVKPFEEALFKLKEGQISDVVKTEYGYHIIRA----DK 245
Cdd:PRK03095 157 ------------KSFEELAKQYSEDTgSKEKGGDLGFFGAGKMVKEFEDAAYKLKKDEVSEPVKSQFGYHIIKVtdikEP 224

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 517994778 246 EDDFDKEKSKLKEKIIQNKLQeDPKILTDAYKDLLDEYNVDYKDRDVKKAIED 298
Cdd:PRK03095 225 EKSFEQSKADIKKELVQKKAQ-DGEFMNDLMMKEIKKADVKVDDKDLKDLFEE 276
prsA PRK02998
peptidylprolyl isomerase; Reviewed
 1-297 8.07e-20

peptidylprolyl isomerase; Reviewed


Pssm-ID: 179522 [Multi-domain]  Cd Length: 283  Bit Score: 87.33  E-value: 8.07e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778   1 MKKgiQKLFIP--ITASAVLLGACGNDaptskdQTLISSKAGDVKVEDVLKEIGNDQIASQSFKVLLDKILEKKYgdKVD 78
Cdd:PRK02998   1 MKK--KKLFLGtiISCVVLALSACGSS------DNVVTSKVGNITEKELSKELRQKYGESTLYQMVLSKALLDKY--KVS 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  79 QKQIDKETDEEIEKYGGKkqFENLLKQQGMTIDDYKKQR--KLVSYQKELlneKVKVSDKEIKENTK---KASHILIK-V 152
Cdd:PRK02998  71 DEEAKKQVEEAKDKMGDN--FKSTLEQVGLKNEDELKEKmkPEIAFEKAI---KATVTEKDVKDNYKpemKVSHILVKdE 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 153 KQDKDDKEGLSdkdakkkieeikekldkNPKDFDKIAKEESMDS-TKDKNGSLGYVIKGQMVKPFEEALFKLKEGQISDV 231
Cdd:PRK02998 146 KTAKEVKEKVN-----------------NGEDFAALAKQYSEDTgSKEQGGEISGFAPGQTVKEFEEAAYKLDAGQVSEP 208

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 232 VKTEYGYHIIR-ADKED--DFDKEKSKLKEKIIQNKLQE-DPKILTDAYKDLLDEYNVDYKDRDVKKAIE 297
Cdd:PRK02998 209 VKTTYGYHIIKvTDKKElkPFDEVKDSIRKDLEQQRLQDtTGKWKQQVVNDLLKDADIKVNDKEFKDTFK 278
Rotamase pfam00639
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 147-245 1.36e-19

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 425792 [Multi-domain]  Cd Length: 96  Bit Score: 81.96  E-value: 1.36e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  147 HILIKVKqdkdDKEGLSDKDAKKKIEEIKEKLDKNPKDFDKIAKEESMD-STKDKNGSLGYVIKGQMVKPFEEALFKLKE 225
Cdd:pfam00639   1 HILIKTP----EASERDRAEAKAKAEEILEQLKSGEDSFAELARKYSDDcPSAANGGDLGWFTRGQLPPEFEKAAFALKP 76

                          90       100
                  ....*....|....*....|
gi 517994778  226 GQISDVVKTEYGYHIIRADK 245
Cdd:pfam00639  77 GEISGPVETRFGFHIIKLTD 96
Rotamase_3 pfam13616
PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the ...
 131-243 3.82e-18

PPIC-type PPIASE domain; Rotamases increase the rate of protein folding by catalysing the interconversion of cis-proline and trans-proline.


Pssm-ID: 404499 [Multi-domain]  Cd Length: 116  Bit Score: 78.56  E-value: 3.82e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  131 VKVSDKEIKENTKKASHILIKVKQDKDDKEGLSDKDAKKKIEEIkekldKNPKDFDKIAKEESMD-STKDKNGSLGYVIK 209
Cdd:pfam13616   4 SKLVDKKSAPDSVKASHILISYSQAVSRTEEEAKAKADSLLAAL-----KNGADFAALAKTYSDDpASKNNGGDLGWFTK 78

                          90       100       110
                  ....*....|....*....|....*....|....
gi 517994778  210 GQMVKPFEEALFKLKEGQISDVVKTEYGYHIIRA 243
Cdd:pfam13616  79 GQMVKEFEDAVFSLKVGEISGVVKTQFGFHIIKV 112
PTZ00356 PTZ00356
peptidyl-prolyl cis-trans isomerase (PPIase); Provisional
 144-241 7.70e-18

peptidyl-prolyl cis-trans isomerase (PPIase); Provisional


Pssm-ID: 185573 [Multi-domain]  Cd Length: 115  Bit Score: 77.76  E-value: 7.70e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 144 KASHILIK-------VKQDKDDKEGLSDKDAKKKIEEIKEKLDKNPKDFDKIAKEESMDSTKDKNGSLGYVIKGQMVKPF 216
Cdd:PTZ00356   7 RAAHLLIKhtgsrnpVSRRTGKPVTRSKEEAIKELAKWREQIVSGEKTFEEIARQRSDCGSAAKGGDLGFFGRGQMQKPF 86

                         90       100
                 ....*....|....*....|....*
gi 517994778 217 EEALFKLKEGQISDVVKTEYGYHII 241
Cdd:PTZ00356  87 EDAAFALKVGEISDIVHTDSGVHII 111
prsA PRK03002
peptidylprolyl isomerase PrsA;
3-293 9.50e-18

peptidylprolyl isomerase PrsA;


Pssm-ID: 101162 [Multi-domain]  Cd Length: 285  Bit Score: 81.52  E-value: 9.50e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778   3 KGIQKLFIPITASAVLLGACGNDAPTSkdqTLISSKAGDVKVEDVLKEIGNDQIASQSFKVLLDKILEKKYgdKVDQKQI 82
Cdd:PRK03002   2 RGKHIFIITALISILMLSACGQKNSSA---TVATATDSTITKSDFEKQLKDRYGKDMLYEMMAQDVITKKY--KVSDDDV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  83 DKETDEEIEKYGgkKQFENLLKQQGMTI-DDYKKQRKLvsyqKELLNEKVK--VSDKEIKENTK---KASHILIKVKQDK 156
Cdd:PRK03002  77 DKEVQKAKSQYG--DQFKNVLKNNGLKDeADFKNQIKF----KLAMNEAIKksVTEKDVKDHYKpeiKASHILVSDENEA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 157 DDKEGLSDKDAkkkieeikekldknpkDFDKIAKEESMD-STKDKNGSLGYVIKGQMVKPFEEALFKLKEGQISDVVKTE 235
Cdd:PRK03002 151 KEIKKKLDAGA----------------SFEELAKQESQDlLSKEKGGDLGYFNSGRMAPEFETAAYKLKVGQISNPVKSP 214

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517994778 236 YGYHIIRADKEDDFdKEKSKLKEKIIQNKLQE---DPKILTDAYKDLLDEYNVDYKDRDVK 293
Cdd:PRK03002 215 NGYHIIKLTDKKDL-KPYDEVKDSIRKNLEEErtaDPIFGKKLLQSELKKANIKINDSELE 274
prsA PRK01326
foldase protein PrsA; Reviewed
 14-290 5.51e-17

foldase protein PrsA; Reviewed


Pssm-ID: 179281 [Multi-domain]  Cd Length: 310  Bit Score: 79.86  E-value: 5.51e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  14 ASAVLLGACGNdapTSKDQTLISSKAGDVKVEDVLKEIGNDQIASQS-FKVLLDKILEKKYGDKVDQKQIDKETDEEIEK 92
Cdd:PRK01326  13 LSVATLAACSK---TNENTKVISMKGDTITVSDFYNQVKNNPSAQQAmLNLTISRVFEKQYGDKVSDKEVEKAYAKTAKQ 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  93 YGgkKQFENLLKQQGMTIDDYKKQ---RKLVSY------QKELLNEKVKvsdKEIKENTKKASHILIKVKQDKDDKEGLS 163
Cdd:PRK01326  90 YG--ASFSRALAQAGLTPETYKAQirtSKLVEYavkeaaKKELTDEAYK---KAYEEYTPEVTAQIIRLDNEDKAKSVLE 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 164 DKDAKKKieeikekldknpkDFDKIAKEESmdSTKDKNGSLGYVIKGQMV-KPFEEALFKLKEGQISDVVKT------EY 236
Cdd:PRK01326 165 EAKAEGA-------------DFAQIAKENT--TTKEKKGEYKFDSGSTNVpEQVKKAAFALDEDGVSDVISVldptayQS 229

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 517994778 237 GYHII----RADKEDDFDKEKSKLKEKIIQNKlQEDPKILTDAYKDLLDEYNVDYKDR 290
Cdd:PRK01326 230 KYYIVkvtkKTEKKSDWKDYKKRLKAIILAQK-QNDSNFQNKVIAKALDKANVKIKDK 286
PRK12450 PRK12450
foldase protein PrsA; Reviewed
 14-312 2.08e-16

foldase protein PrsA; Reviewed


Pssm-ID: 138982 [Multi-domain]  Cd Length: 309  Bit Score: 78.21  E-value: 2.08e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  14 ASAVLLGACGNdapTSKDQTLISSKAGDVKVEDVLKEIGNDQIASQS-FKVLLDKILEKKYGDKVDQKQIDKETDEEIEK 92
Cdd:PRK12450  15 ATVVTLSACQS---SHNNTKLVSMKGDTITVSDFYNETKNTELAQKAmLSLVISRVFETQYANKVSDKEVEKAYKQTADQ 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  93 YGGkkQFENLLKQQGMTIDDYKKQ---RKLVSYQKELLNEKVKVSDKEIKEN----TKKASHILIKVKQDKDDKEGLSDK 165
Cdd:PRK12450  92 YGT--SFKTVLAQSGLTPETYKKQirlTKLVEYAVKEQAKNETISKKDYRQAydayTPTMTAEIMQFEKEEDAKAALEAV 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 166 DAKKKieeikekldknpkDFDKIAKEESMDSTKDKNGSLGyviKGQMVKPFE--EALFKLKEGQISDVVK------TEYG 237
Cdd:PRK12450 170 KAEGA-------------DFAAIAKEKTIAADKKTTYTFD---SGETTLPAEvvRAASGLKEGNRSEIITaldpatSKRT 233

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517994778 238 YHII----RADKEDDFDKEKSKLKEKIIQNKLQeDPKILTDAYKDLLDEYNVDYKDRDVKKaIEDNILNPDalKKQSSQ 312
Cdd:PRK12450 234 YHIIkvtkKATKKADWKAYQKRLKDIIVTGKLK-DPDFQNKVIAKALDKANVKIKDKAFAN-ILAQFAKPN--QKQPAQ 308
prsA PRK00059
peptidylprolyl isomerase; Provisional
 62-301 3.12e-16

peptidylprolyl isomerase; Provisional


Pssm-ID: 234605 [Multi-domain]  Cd Length: 336  Bit Score: 77.83  E-value: 3.12e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  62 KVLLDKilEKKYGDKVDQKQIDKETDEEI-----EKYGGKKQFENLLKQQGMTIDDYKKQRKLVSYQKELLNE---KVKV 133
Cdd:PRK00059  97 KVLLQK--AKELKLIPSEEELNKEVDKKIneikkQFNNDEEQFEEALKATGFTEETFKEYLKNQIIIEKVINEvvkDVKV 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 134 SDKEIKE-------------NTKKASHILIKVKQD-KDDKEGLSDKdakkkieeikekldknpKDFDKIAKEESMD-STK 198
Cdd:PRK00059 175 TDKDAQKyynenkskftekpNTMHLAHILVKTEDEaKKVKKRLDKG-----------------EDFAKVAKEVSQDpGSK 237

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 199 DKNGSLGYV--IKGQMVKPFEEALFKLKEGQISDVVKTEYGYHIIRADKEDDFD-KEKSKLKEKIIQNKLQEDPKiltDA 275
Cdd:PRK00059 238 DKGGDLGDVpySDSGYDKEFMDGAKALKEGEISAPVKTQFGYHIIKAIKKKEYPvKPFDSVKEDIKKQLLQEKQS---EV 314

                        250       260
                 ....*....|....*....|....*.
gi 517994778 276 YKDLLDEYNvdyKDRDVKKAiEDNIL 301
Cdd:PRK00059 315 FKKKIEEWK---KALKVKKY-EKNLL 336
PRK15441 PRK15441
peptidyl-prolyl cis-trans isomerase C; Provisional
 180-242 1.59e-07

peptidyl-prolyl cis-trans isomerase C; Provisional


Pssm-ID: 185338 [Multi-domain]  Cd Length: 93  Bit Score: 48.48  E-value: 1.59e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517994778 180 KNPKDFDKIAKEESMDSTKDKNGSLGYVIKGQMVKPFEEALFKLKEGQISDVVKTEYGYHIIR 242
Cdd:PRK15441  26 KNGADFGKLAKKHSICPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIK 88
PRK10788 PRK10788
periplasmic folding chaperone; Provisional
 86-264 8.28e-06

periplasmic folding chaperone; Provisional


Pssm-ID: 182731 [Multi-domain]  Cd Length: 623  Bit Score: 47.31  E-value: 8.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778  86 TDEEIekyggkKQFENLLKQQGMTIDDYKkqrklVSYQK---ELLNEKVKVSDKEIKE------------NTKKAShiLI 150
Cdd:PRK10788 210 TDEEI------KSYYDQNKNNFMAPEQFK-----VSYIKldaATMQQKITVSDADIQAyydqhqdqftqpERKRYS--II 276

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 151 KVKQDKDDKEGLsdkDAKkkieeikekldKNPKDFDKIAKEESMDSTKDKN-GSLGYVIKGQMVKPFEEAlfKLKE-GQI 228
Cdd:PRK10788 277 QTKTEAEAKAVL---DEL-----------KKGADFATLAKEKSTDIISARNgGDLGWLEPATTPDELKNA--GLKEkGQL 340

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 517994778 229 SDVVKTEYGYHIIRAD-----KEDDFDKEKSKLKEKIIQNK 264
Cdd:PRK10788 341 SGVIKSSVGFLIVRLDdiqpaKVKPLSEVRDDIAAKVKQEK 381
PRK10770 PRK10770
peptidyl-prolyl cis-trans isomerase SurA; Provisional
 144-254 1.23e-04

peptidyl-prolyl cis-trans isomerase SurA; Provisional


Pssm-ID: 236758 [Multi-domain]  Cd Length: 413  Bit Score: 43.19  E-value: 1.23e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517994778 144 KASHILIKVKQDkddkegLSDKDAKKKIEEIKEKLDKNPKDFDKIAKEESMD-STKDKNGSLGYVIKGQMVKPFEEALFK 222
Cdd:PRK10770 268 HARHILLKPSPI------MTDEQARAKLEQIAADIKSGKTTFAAAAKEFSQDpGSANQGGDLGWATPDIFDPAFRDALMR 341

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 517994778 223 LKEGQISDVVKTEYGYHII------RADKEDDFDKEKS 254
Cdd:PRK10770 342 LNKGQISAPVHSSFGWHLIelldtrQVDKTDAAQKDRA 379
Rotamase_2 pfam13145
PPIC-type PPIASE domain;
180-245 2.26e-03

PPIC-type PPIASE domain;


Pssm-ID: 432992 [Multi-domain]  Cd Length: 121  Bit Score: 37.42  E-value: 2.26e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517994778  180 KNPKDFDKIAKEESMDSTKDKngslGYVIKGQMVKPFEEALFKLKEGQISDVVKTEYGYHIIRADK 245
Cdd:pfam13145  46 GALEDFAALAKGEGIKAATLD----IVESAELLPEELAKAAFALKPGEVSGPIKTGNGYYVVRVTE 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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