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Conserved domains on  [gi|517999067|ref|WP_019169275|]
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GNAT family N-acetyltransferase [Staphylococcus intermedius]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11447421)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 1-153 3.03e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 63.48  E-value: 3.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067   1 MTIKSKRfddITIQLYDKQYRDALYQFELSERQRIYSSLPKEVLDDALNDKNRVAN-----------IVLNDQDEVIGFF 69
Cdd:COG1670    1 PTLETER---LRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLAdwadggalpfaIEDKEDGELIGVV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  70 VLHQhyqhegYDTPYEVVYIrSLSINEAYQGNGYGTKIMMILPEYvqmIF--PDFNHLYLVVDAENEAAWNVYERAGFMH 147
Cdd:COG1670   78 GLYD------IDRANRSAEI-GYWLAPAYWGKGYATEALRALLDY---AFeeLGLHRVEAEVDPDNTASIRVLEKLGFRL 147


                 ....*.
gi 517999067 148 TATKEE 153
Cdd:COG1670  148 EGTLRD 153
NAT_SF super family cl17182
N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of ...
 199-269 2.04e-03

N-Acyltransferase superfamily: Various enyzmes that characteristicly catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase which catalyze the transfer of an acetyl group to a substrate. The mechanism is an ordered Bi-Bi ternary complex kinetic mechanism for most GNATs: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and then CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/ph enylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


The actual alignment was detected with superfamily member pfam00583:

Pssm-ID: 473072 [Multi-domain]  Cd Length: 116  Bit Score: 37.11  E-value: 2.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517999067  199 VGFLAIEAFNE---RLIIRALYVDDAHRDTGIAQNALRQLATYVRKENHDTKVIEVTLfgPNHQLTPLFLKSNF 269
Cdd:pfam00583  45 VGFASLSIIDDeppVGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCERIFLEVAA--DNLAAIALYEKLGF 116
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 1-153 3.03e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 63.48  E-value: 3.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067   1 MTIKSKRfddITIQLYDKQYRDALYQFELSERQRIYSSLPKEVLDDALNDKNRVAN-----------IVLNDQDEVIGFF 69
Cdd:COG1670    1 PTLETER---LRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLAdwadggalpfaIEDKEDGELIGVV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  70 VLHQhyqhegYDTPYEVVYIrSLSINEAYQGNGYGTKIMMILPEYvqmIF--PDFNHLYLVVDAENEAAWNVYERAGFMH 147
Cdd:COG1670   78 GLYD------IDRANRSAEI-GYWLAPAYWGKGYATEALRALLDY---AFeeLGLHRVEAEVDPDNTASIRVLEKLGFRL 147


                 ....*.
gi 517999067 148 TATKEE 153
Cdd:COG1670  148 EGTLRD 153
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 22-145 5.13e-12

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 61.38  E-value: 5.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067   22 DALYQFELSERQRIYSSLPKEVLDDALNDKNRVAnIVLNDQDEVIGFFVLHQHYQHEGydtpyeVVYIRSLSINEAYQGN 101
Cdd:pfam00583   2 EALYELLSEEFPEPWPDEPLDLLEDWDEDASEGF-FVAEEDGELVGFASLSIIDDEPP------VGEIEGLAVAPEYRGK 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 517999067  102 GYGTKIMMILPEYvqMIFPDFNHLYLVVDAENEAAWNVYERAGF 145
Cdd:pfam00583  75 GIGTALLQALLEW--ARERGCERIFLEVAADNLAAIALYEKLGF 116
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 57-108 7.77e-05

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 39.95  E-value: 7.77e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 517999067  57 IVLNDQDEVIGFFVLHQHYQHEGYdtpyevVYIRSLSINEAYQGNGYGTKIM 108
Cdd:cd04301    2 LVAEDDGEIVGFASLSPDGSGGDT------AYIGDLAVLPEYRGKGIGSALL 47
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 199-269 2.04e-03

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 37.11  E-value: 2.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517999067  199 VGFLAIEAFNE---RLIIRALYVDDAHRDTGIAQNALRQLATYVRKENHDTKVIEVTLfgPNHQLTPLFLKSNF 269
Cdd:pfam00583  45 VGFASLSIIDDeppVGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCERIFLEVAA--DNLAAIALYEKLGF 116
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 199-283 3.87e-03

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 36.96  E-value: 3.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067 199 VGFLAIEAFN-ERLIIRALYVDDAHRDTGIAQNALRQLATYVRKenHDTKVIEVTLFGPNHQLTPLFLKSNF--VETVTT 275
Cdd:COG0454   46 IGFAGLRRLDdKVLELKRLYVLPEYRGKGIGKALLEALLEWARE--RGCTALELDTLDGNPAAIRFYERLGFkeIERYVA 123


                 ....*...
gi 517999067 276 DDYVTFEK 283
Cdd:COG0454  124 YVGGEFEK 131
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
 94-146 4.28e-03

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 37.47  E-value: 4.28e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 517999067  94 INEAYQGNGYGTKIMMILPEYVQMIFpDFNHLYLVVDAENEAAWNVYERAGFM 146
Cdd:PRK15130  90 ISPEYQGKGLATRAAKLAMDYGFTVL-NLYKLYLIVDKENEKAIHIYRKLGFE 141
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 1-153 3.03e-12

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 63.48  E-value: 3.03e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067   1 MTIKSKRfddITIQLYDKQYRDALYQFELSERQRIYSSLPKEVLDDALNDKNRVAN-----------IVLNDQDEVIGFF 69
Cdd:COG1670    1 PTLETER---LRLRPLRPEDAEALAELLNDPEVARYLPGPPYSLEEARAWLERLLAdwadggalpfaIEDKEDGELIGVV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  70 VLHQhyqhegYDTPYEVVYIrSLSINEAYQGNGYGTKIMMILPEYvqmIF--PDFNHLYLVVDAENEAAWNVYERAGFMH 147
Cdd:COG1670   78 GLYD------IDRANRSAEI-GYWLAPAYWGKGYATEALRALLDY---AFeeLGLHRVEAEVDPDNTASIRVLEKLGFRL 147


                 ....*.
gi 517999067 148 TATKEE 153
Cdd:COG1670  148 EGTLRD 153
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 22-145 5.13e-12

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 61.38  E-value: 5.13e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067   22 DALYQFELSERQRIYSSLPKEVLDDALNDKNRVAnIVLNDQDEVIGFFVLHQHYQHEGydtpyeVVYIRSLSINEAYQGN 101
Cdd:pfam00583   2 EALYELLSEEFPEPWPDEPLDLLEDWDEDASEGF-FVAEEDGELVGFASLSIIDDEPP------VGEIEGLAVAPEYRGK 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 517999067  102 GYGTKIMMILPEYvqMIFPDFNHLYLVVDAENEAAWNVYERAGF 145
Cdd:pfam00583  75 GIGTALLQALLEW--ARERGCERIFLEVAADNLAAIALYEKLGF 116
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
23-166 6.31e-11

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 59.62  E-value: 6.31e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  23 ALYQFELSERQRIYSSLPKEVLD----DALNDKNRVANIVLNDQDEVIGFFVLHQHYQHEGYDTPYEV-VYIRslsinEA 97
Cdd:COG1247   17 AIYNEAIAEGTATFETEPPSEEEreawFAAILAPGRPVLVAEEDGEVVGFASLGPFRPRPAYRGTAEEsIYVD-----PD 91

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517999067  98 YQGNGYGTKIMmilpEYVQMIFPD--FNHLYLVVDAENEAAWNVYERAGFMHTATKEEgpIGKERLYYLDL 166
Cdd:COG1247   92 ARGRGIGRALL----EALIERARArgYRRLVAVVLADNEASIALYEKLGFEEVGTLPE--VGFKFGRWLDL 156
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 67-175 2.06e-08

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 50.81  E-value: 2.06e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  67 GFFVLHQHYQHEgydtpyeVVYIRSLSINEAYQGNGYGTKIMmilpEYVQMIFPD--FNHLYLVVDAENEAAWNVYERAG 144
Cdd:COG0456    1 GFALLGLVDGGD-------EAEIEDLAVDPEYRGRGIGRALL----EAALERARErgARRLRLEVREDNEAAIALYEKLG 69

                         90       100       110
                 ....*....|....*....|....*....|.
gi 517999067 145 FMhtatkeegPIGKERLYYLDLDHKYVSSLK 175
Cdd:COG0456   70 FE--------EVGERPNYYGDDALVMEKELA 92
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
42-166 9.65e-06

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 44.31  E-value: 9.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  42 EVLDDALNDKNRVANIVLNDQDEVIGFFVLHqhyqHEGYDTPYEVVYIRSLSINEAYQGNGYGTKIMmilpEYVQMIFPD 121
Cdd:COG3153   27 ELVDRLREDPAAGLSLVAEDDGEIVGHVALS----PVDIDGEGPALLLGPLAVDPEYRGQGIGRALM----RAALEAARE 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 517999067 122 FNHLYLVVDAeNEAAWNVYERAGFMHTATKEEGPIGKERLYYLDL 166
Cdd:COG3153   99 RGARAVVLLG-DPSLLPFYERFGFRPAGELGLTLGPDEVFLAKEL 142
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 57-145 2.26e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 42.06  E-value: 2.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067   57 IVLNDQDEVIGFFVLHQHYQHEgydtpyeVVYIRSLSINEAYQGNGYGTKIMmilpEYVQMIFPDFNHLYLVVDAENEAA 136
Cdd:pfam13508   6 FVAEDDGKIVGFAALLPLDDEG-------ALAELRLAVHPEYRGQGIGRALL----EAAEAAAKEGGIKLLELETTNRAA 74


                  ....*....
gi 517999067  137 wNVYERAGF 145
Cdd:pfam13508  75 -AFYEKLGF 82
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 57-145 2.63e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 43.12  E-value: 2.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  57 IVLNDQDEVIGFFVLHQhyqhegydTPYEVVYIRSLSINEAYQGNGYGTKIMMILPEYVQMIfpDFNHLYLVVDAENEAA 136
Cdd:COG0454   37 IAVDDKGEPIGFAGLRR--------LDDKVLELKRLYVLPEYRGKGIGKALLEALLEWARER--GCTALELDTLDGNPAA 106


                 ....*....
gi 517999067 137 WNVYERAGF 145
Cdd:COG0454  107 IRFYERLGF 115
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
86-150 4.16e-05

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 41.43  E-value: 4.16e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 517999067  86 VVYIRSLSINEAYQGNGYGTKIMMILpeyVQMIFPD-FNHLYLVVDAENEAAWNVYERAGFMHTAT 150
Cdd:COG3393   15 VAEISGVYTHPEYRGRGLASALVAAL---AREALARgARTPFLYVDADNPAARRLYERLGFRPVGE 77
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 57-145 6.14e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 41.95  E-value: 6.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067   57 IVLNDqDEVIGFFVLhqhYQHEGYDTPYEVVYIrslsINEAYQGNGYGTKIMMILPEYVqMIFPDFNHLYLVVDAENEAA 136
Cdd:pfam13302  59 IELKD-TGFIGSIGL---YDIDGEPERAELGYW----LGPDYWGKGYATEAVRALLEYA-FEELGLPRLVARIDPENTAS 129


                  ....*....
gi 517999067  137 WNVYERAGF 145
Cdd:pfam13302 130 RRVLEKLGF 138
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 57-108 7.77e-05

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 39.95  E-value: 7.77e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 517999067  57 IVLNDQDEVIGFFVLHQHYQHEGYdtpyevVYIRSLSINEAYQGNGYGTKIM 108
Cdd:cd04301    2 LVAEDDGEIVGFASLSPDGSGGDT------AYIGDLAVLPEYRGKGIGSALL 47
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 41-167 8.91e-05

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 41.52  E-value: 8.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067  41 KEVLDDALNDKNRVANIVLNDQDEVIGFFVLHQHyqhegydtPYEVVYIRSLSINEAYQGNGYGTKIMMILPEYVQMIfp 120
Cdd:COG1246   15 LELIRPYALEEEIGEFWVAEEDGEIVGCAALHPL--------DEDLAELRSLAVHPDYRGRGIGRRLLEALLAEAREL-- 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 517999067 121 DFNHLYLVVdaeNEAAWNVYERAGFmHTATKEEGPIGK-----ERLYYLDLD 167
Cdd:COG1246   85 GLKRLFLLT---TSAAIHFYEKLGF-EEIDKEDLPYAKvwqrdSVVMEKDLE 132
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 199-269 2.04e-03

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 37.11  E-value: 2.04e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 517999067  199 VGFLAIEAFNE---RLIIRALYVDDAHRDTGIAQNALRQLATYVRKENHDTKVIEVTLfgPNHQLTPLFLKSNF 269
Cdd:pfam00583  45 VGFASLSIIDDeppVGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCERIFLEVAA--DNLAAIALYEKLGF 116
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 199-283 3.87e-03

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 36.96  E-value: 3.87e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999067 199 VGFLAIEAFN-ERLIIRALYVDDAHRDTGIAQNALRQLATYVRKenHDTKVIEVTLFGPNHQLTPLFLKSNF--VETVTT 275
Cdd:COG0454   46 IGFAGLRRLDdKVLELKRLYVLPEYRGKGIGKALLEALLEWARE--RGCTALELDTLDGNPAAIRFYERLGFkeIERYVA 123


                 ....*...
gi 517999067 276 DDYVTFEK 283
Cdd:COG0454  124 YVGGEFEK 131
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
 94-146 4.28e-03

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 37.47  E-value: 4.28e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 517999067  94 INEAYQGNGYGTKIMMILPEYVQMIFpDFNHLYLVVDAENEAAWNVYERAGFM 146
Cdd:PRK15130  90 ISPEYQGKGLATRAAKLAMDYGFTVL-NLYKLYLIVDKENEKAIHIYRKLGFE 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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