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Conserved domains on  [gi|517999157|ref|WP_019169365|]
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carbonic anhydrase [Staphylococcus intermedius]

Protein Classification

beta-class carbonic anhydrase( domain architecture ID 10130171)

beta-class carbonic anhydrase similar to carbonic anhydrase (CA) that catalyzes the zinc-dependent reversible hydration of carbon dioxide into bicarbonate and a proton, and to carbon disulfide hydrolase that catalyzes the conversion of carbon disulfide into hydrogen sulfide and carbon dioxide, with carbonyl sulfide as an intermediate

Gene Ontology:  GO:0004089|GO:0008270

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
beta_CA_cladeD cd03379
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ...
 29-181 8.18e-49

Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.


:

Pssm-ID: 239474  Cd Length: 142  Bit Score: 155.49  E-value: 8.18e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  29 PSKKAVLLTCMDTRLQDLstKALGFNNGDLKVVKNAGATISHpfgSTMRSLLVGIYALGAEEIIIMGHKDCGMGNINVDE 108
Cdd:cd03379    1 PARKLAIVTCMDARLDPE--KALGLKLGDAKVIRNAGGRVTD---DAIRSLVVSVYLLGTREIIVIHHTDCGMLTFTDEE 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517999157 109 VMTTMQQRGVDQQvidilnYSGIDVSNFLKGFDDVYDNVKHNIDMIYEHPLFDNKVPVHGLVIDPHTGELDLV 181
Cdd:cd03379   76 LKEKMKERGIAEA------YGGIDKEFWFLGFDDLEESVREDVERIRNHPLIPDDVPVHGYVYDVKTGKLTEV 142
 
Name Accession Description Interval E-value
beta_CA_cladeD cd03379
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ...
 29-181 8.18e-49

Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.


Pssm-ID: 239474  Cd Length: 142  Bit Score: 155.49  E-value: 8.18e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  29 PSKKAVLLTCMDTRLQDLstKALGFNNGDLKVVKNAGATISHpfgSTMRSLLVGIYALGAEEIIIMGHKDCGMGNINVDE 108
Cdd:cd03379    1 PARKLAIVTCMDARLDPE--KALGLKLGDAKVIRNAGGRVTD---DAIRSLVVSVYLLGTREIIVIHHTDCGMLTFTDEE 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517999157 109 VMTTMQQRGVDQQvidilnYSGIDVSNFLKGFDDVYDNVKHNIDMIYEHPLFDNKVPVHGLVIDPHTGELDLV 181
Cdd:cd03379   76 LKEKMKERGIAEA------YGGIDKEFWFLGFDDLEESVREDVERIRNHPLIPDDVPVHGYVYDVKTGKLTEV 142
Pro_CA smart00947
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ...
 26-181 1.13e-33

Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.


Pssm-ID: 214929 [Multi-domain]  Cd Length: 154  Bit Score: 117.22  E-value: 1.13e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157    26 SKTPSKKAVLLTCMDTRLQDLstKALGFNNGDLKVVKNAGATISHPFGSTMRSLLVGIYALGAEEIIIMGHKDCGMGNIN 105
Cdd:smart00947   1 AKGQHPKALIIGCSDSRVPPE--LIFGLGPGDLFVIRNAGNIVPPYDDGVLASLEYAVEVLGVKEIVVCGHTDCGAVKAA 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517999157   106 VDEVMTTMQQ--RGVDQQVIDILNYSGIDVSNFLKGFDDVYDNVKHNIDmIYEHPLfDNKVPVHGLVIDPHTGELDLV 181
Cdd:smart00947  79 LDDEPGLIDNwlERIRPARERALEELGDVDALEELNVRDQVENLRTSPA-IREAVA-KGKLKVHGWVYDIETGKLEVL 154
Pro_CA pfam00484
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ...
 33-178 3.26e-23

Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.


Pssm-ID: 459828  Cd Length: 156  Bit Score: 90.26  E-value: 3.26e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157   33 AVLLTCMDTRLqdLSTKALGFNNGDLKVVKNAGATISHPFGSTMRSLLVGIYALGAEEIIIMGHKDCGMGNINVDEVMTT 112
Cdd:pfam00484   1 ALIIGCSDSRV--PPELIFDTGPGDLFVVRNAGNLVPPYDLNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALDAAGPA 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517999157  113 MQQRGVDqQVIDILNYSGIDVSNFLKGFDDVYD--------NVKHNIDMIYEHP-----LFDNKVPVHGLVIDPHTGEL 178
Cdd:pfam00484  79 ELPGFID-NWLRHIRPAVERVAEELESLDDPEErddaleelNVREQVENLRTFPivreaVAKGKLKIHGWVYDLETGEV 156
CynT COG0288
Carbonic anhydrase [Inorganic ion transport and metabolism];
1-181 1.09e-12

Carbonic anhydrase [Inorganic ion transport and metabolism];


Pssm-ID: 440057  Cd Length: 204  Bit Score: 63.64  E-value: 1.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157   1 MTLLEHILEYNEEFVANKA------YEAYSTSKTPskKAVLLTCMDTRL-------QDLstkalgfnnGDLKVVKNAGAT 67
Cdd:COG0288    1 MEALKRLLEGNRRFVAGKFpqdperFEELAKGQHP--FALVIGCSDSRVppelifdQGP---------GDLFVVRNAGNV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  68 ISHPFGSTMRSLLVGIYALGAEEIIIMGHKDCG-------------MGNIN---------VDEVMTTMQQRGVDQQViDI 125
Cdd:COG0288   70 VPPYDPGVLASIEYAVEVLGVKLIVVLGHSGCGavkaaldgleleeLGLIGnwlrhirpaVERVRAELPAADGEERL-DR 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517999157 126 LnysgidvsnflkgfddVYDNVKHNIDMIYEHPLF-----DNKVPVHGLVIDPHTGELDLV 181
Cdd:COG0288  149 L----------------VELNVREQVENLRTSPIVreavaAGKLKVHGWVYDLATGRVEFL 193
PLN03006 PLN03006
carbonate dehydratase
 8-100 3.55e-04

carbonate dehydratase


Pssm-ID: 178583  Cd Length: 301  Bit Score: 40.11  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157   8 LEYNEEFvanKAYEAYSTSKTPskKAVLLTCMDTRLqdLSTKALGFNNGDLKVVKNAgATISHPFGS----TMRSLLVGI 83
Cdd:PLN03006  95 LKYMDDF---EHYKNLADAQAP--KFLVIACADSRV--CPSAVLGFQPGDAFTVRNI-ANLVPPYESgpteTKAALEFSV 166

                         90
                 ....*....|....*..
gi 517999157  84 YALGAEEIIIMGHKDCG 100
Cdd:PLN03006 167 NTLNVENILVIGHSRCG 183
 
Name Accession Description Interval E-value
beta_CA_cladeD cd03379
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ...
 29-181 8.18e-49

Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.


Pssm-ID: 239474  Cd Length: 142  Bit Score: 155.49  E-value: 8.18e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  29 PSKKAVLLTCMDTRLQDLstKALGFNNGDLKVVKNAGATISHpfgSTMRSLLVGIYALGAEEIIIMGHKDCGMGNINVDE 108
Cdd:cd03379    1 PARKLAIVTCMDARLDPE--KALGLKLGDAKVIRNAGGRVTD---DAIRSLVVSVYLLGTREIIVIHHTDCGMLTFTDEE 75

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517999157 109 VMTTMQQRGVDQQvidilnYSGIDVSNFLKGFDDVYDNVKHNIDMIYEHPLFDNKVPVHGLVIDPHTGELDLV 181
Cdd:cd03379   76 LKEKMKERGIAEA------YGGIDKEFWFLGFDDLEESVREDVERIRNHPLIPDDVPVHGYVYDVKTGKLTEV 142
Pro_CA smart00947
Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the ...
 26-181 1.13e-33

Carbonic anhydrase; Carbonic anhydrases (CA) are zinc metalloenzymes which catalyze the reversible hydration of carbon dioxide. In Escherichia coli, CA (gene cynT) is involved in recycling carbon dioxide formed in the bicarbonate-dependent decomposition of cyanate by cyanase (gene cynS). By this action, it prevents the depletion of cellular bicarbonate. In photosynthetic bacteria and plant chloroplast, CA is essential to inorganic carbon fixation. Prokaryotic and plant chloroplast CA are structurally and evolutionary related and form a family distinct from the one which groups the many different forms of eukaryotic CA's.


Pssm-ID: 214929 [Multi-domain]  Cd Length: 154  Bit Score: 117.22  E-value: 1.13e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157    26 SKTPSKKAVLLTCMDTRLQDLstKALGFNNGDLKVVKNAGATISHPFGSTMRSLLVGIYALGAEEIIIMGHKDCGMGNIN 105
Cdd:smart00947   1 AKGQHPKALIIGCSDSRVPPE--LIFGLGPGDLFVIRNAGNIVPPYDDGVLASLEYAVEVLGVKEIVVCGHTDCGAVKAA 78

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 517999157   106 VDEVMTTMQQ--RGVDQQVIDILNYSGIDVSNFLKGFDDVYDNVKHNIDmIYEHPLfDNKVPVHGLVIDPHTGELDLV 181
Cdd:smart00947  79 LDDEPGLIDNwlERIRPARERALEELGDVDALEELNVRDQVENLRTSPA-IREAVA-KGKLKVHGWVYDIETGKLEVL 154
beta_CA cd00382
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ...
 29-181 2.04e-29

Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.


Pssm-ID: 238224 [Multi-domain]  Cd Length: 119  Bit Score: 105.27  E-value: 2.04e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  29 PSKKAVLLTCMDTRLqdLSTKALGFNNGDLKVVKNAGATISHPFGSTMRSLLVGIYALGAEEIIIMGHKDCGMgninvde 108
Cdd:cd00382    1 QKPKALIIGCSDSRV--PPELIFGLGPGDLFVVRNAGNLVPPYDLDVLASLEYAVEVLGVKHIIVCGHTDCGA------- 71

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 517999157 109 vMTTMQQRGVDQQVIDILNYSGIdvsnflkgfddvydnvkhnidmiyEHPLFDNKVPVHGLVIDPHTGELDLV 181
Cdd:cd00382   72 -VKALVEENVREQVENLRSHPLI------------------------QEAVAPGELKVHGWVYDIETGKLEVL 119
Pro_CA pfam00484
Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of ...
 33-178 3.26e-23

Carbonic anhydrase; This family includes carbonic anhydrases as well as a family of non-functional homologs related to YbcF.


Pssm-ID: 459828  Cd Length: 156  Bit Score: 90.26  E-value: 3.26e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157   33 AVLLTCMDTRLqdLSTKALGFNNGDLKVVKNAGATISHPFGSTMRSLLVGIYALGAEEIIIMGHKDCGMGNINVDEVMTT 112
Cdd:pfam00484   1 ALIIGCSDSRV--PPELIFDTGPGDLFVVRNAGNLVPPYDLNVLASIEYAVEVLKVKHIVVCGHSGCGAVKAALDAAGPA 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 517999157  113 MQQRGVDqQVIDILNYSGIDVSNFLKGFDDVYD--------NVKHNIDMIYEHP-----LFDNKVPVHGLVIDPHTGEL 178
Cdd:pfam00484  79 ELPGFID-NWLRHIRPAVERVAEELESLDDPEErddaleelNVREQVENLRTFPivreaVAKGKLKIHGWVYDLETGEV 156
CynT COG0288
Carbonic anhydrase [Inorganic ion transport and metabolism];
1-181 1.09e-12

Carbonic anhydrase [Inorganic ion transport and metabolism];


Pssm-ID: 440057  Cd Length: 204  Bit Score: 63.64  E-value: 1.09e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157   1 MTLLEHILEYNEEFVANKA------YEAYSTSKTPskKAVLLTCMDTRL-------QDLstkalgfnnGDLKVVKNAGAT 67
Cdd:COG0288    1 MEALKRLLEGNRRFVAGKFpqdperFEELAKGQHP--FALVIGCSDSRVppelifdQGP---------GDLFVVRNAGNV 69

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  68 ISHPFGSTMRSLLVGIYALGAEEIIIMGHKDCG-------------MGNIN---------VDEVMTTMQQRGVDQQViDI 125
Cdd:COG0288   70 VPPYDPGVLASIEYAVEVLGVKLIVVLGHSGCGavkaaldgleleeLGLIGnwlrhirpaVERVRAELPAADGEERL-DR 148

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 517999157 126 LnysgidvsnflkgfddVYDNVKHNIDMIYEHPLF-----DNKVPVHGLVIDPHTGELDLV 181
Cdd:COG0288  149 L----------------VELNVREQVENLRTSPIVreavaAGKLKVHGWVYDLATGRVEFL 193
beta_CA_cladeB cd00884
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ...
 11-100 1.33e-07

Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.


Pssm-ID: 238449  Cd Length: 190  Bit Score: 49.46  E-value: 1.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  11 NEEFVANKA-YEAYSTSKTPskKAVLLTCMDTRLqdLSTKALGFNNGDLKVVKNAGATI-----SHPFGSTMRSLLVGIY 84
Cdd:cd00884    7 KEYFPEERElFEKLAKGQSP--KALFIACSDSRV--VPALITQTQPGELFVVRNVGNLVppyepDGGFHGTSAAIEYAVA 82

                         90
                 ....*....|....*.
gi 517999157  85 ALGAEEIIIMGHKDCG 100
Cdd:cd00884   83 VLKVEHIVVCGHSDCG 98
beta_CA_cladeC cd03378
Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of ...
 4-100 2.51e-06

Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.


Pssm-ID: 239473 [Multi-domain]  Cd Length: 154  Bit Score: 45.21  E-value: 2.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157   4 LEHILEYNEEFVANK-------AYEAYSTSKTPSKKAVLLTCMDTRL-------QDLstkalgfnnGDLKVVKNAGATIS 69
Cdd:cd03378    5 LERLKEGNKRFVSGKplhpdqdLARRRELAKGQKPFAVILSCSDSRVppeiifdQGL---------GDLFVVRVAGNIVD 75

                         90       100       110
                 ....*....|....*....|....*....|.
gi 517999157  70 hpfGSTMRSLLVGIYALGAEEIIIMGHKDCG 100
Cdd:cd03378   76 ---DDVLGSLEYAVEVLGVPLVVVLGHESCG 103
PLN03006 PLN03006
carbonate dehydratase
 8-100 3.55e-04

carbonate dehydratase


Pssm-ID: 178583  Cd Length: 301  Bit Score: 40.11  E-value: 3.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157   8 LEYNEEFvanKAYEAYSTSKTPskKAVLLTCMDTRLqdLSTKALGFNNGDLKVVKNAgATISHPFGS----TMRSLLVGI 83
Cdd:PLN03006  95 LKYMDDF---EHYKNLADAQAP--KFLVIACADSRV--CPSAVLGFQPGDAFTVRNI-ANLVPPYESgpteTKAALEFSV 166

                         90
                 ....*....|....*..
gi 517999157  84 YALGAEEIIIMGHKDCG 100
Cdd:PLN03006 167 NTLNVENILVIGHSRCG 183
PLN02154 PLN02154
carbonic anhydrase
 18-100 5.84e-04

carbonic anhydrase


Pssm-ID: 215111  Cd Length: 290  Bit Score: 39.73  E-value: 5.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  18 KAYEAYSTSKTPskKAVLLTCMDTRLqdLSTKALGFNNGDLKVVKNAgATISHPFGS----TMRSLLVGIYALGAEEIII 93
Cdd:PLN02154  96 EKFKALAIAQSP--KVMVIGCADSRV--CPSYVLGFQPGEAFTIRNV-ANLVTPVQNgpteTNSALEFAVTTLQVENIIV 170


                 ....*..
gi 517999157  94 MGHKDCG 100
Cdd:PLN02154 171 MGHSNCG 177
PLN00416 PLN00416
carbonate dehydratase
 12-100 7.21e-04

carbonate dehydratase


Pssm-ID: 177809  Cd Length: 258  Bit Score: 39.25  E-value: 7.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 517999157  12 EEFVANKA-YEAYSTSKTPskKAVLLTCMDTRLQdlSTKALGFNNGDLKVVKNAgATISHPFGSTMRS-----LLVGIYA 85
Cdd:PLN00416  62 EKYLKNSTlFNHLAKTQTP--KFLVFACSDSRVC--PSHILNFQPGEAFVVRNI-ANMVPPFDQKRHSgvgaaVEYAVVH 136

                         90
                 ....*....|....*
gi 517999157  86 LGAEEIIIMGHKDCG 100
Cdd:PLN00416 137 LKVENILVIGHSCCG 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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