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Conserved domains on  [gi|518020310|ref|WP_019190518|]
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oligopeptide ABC transporter permease OppC [Levyella massiliensis]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 40-316 7.05e-75

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 231.16  E-value: 7.05e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  40 YSYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDsMDTQNINNReawFQPPSLQYPFGTDDVGRNLFDEVWAG 119
Cdd:COG1173    2 RSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYD-PTAQDLAAR---LQPPSAAHWLGTDQLGRDVLSRLLYG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 120 ARTSLFIAFVSTAIVMSIGVVVGMFWGFS-KKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQLIFAMSCTEWIAVA 198
Cdd:COG1173   78 ARISLLVGLLAVLIALVIGVLLGLLAGYFgGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 199 YFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSEAIPSLGRIVQK 278
Cdd:COG1173  158 RLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSE 237

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 518020310 279 NAMFMTSAPYLFIIPLAITALISISLYIVGQTLADASD 316
Cdd:COG1173  238 GRNYLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 40-316 7.05e-75

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 231.16  E-value: 7.05e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  40 YSYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDsMDTQNINNReawFQPPSLQYPFGTDDVGRNLFDEVWAG 119
Cdd:COG1173    2 RSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYD-PTAQDLAAR---LQPPSAAHWLGTDQLGRDVLSRLLYG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 120 ARTSLFIAFVSTAIVMSIGVVVGMFWGFS-KKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQLIFAMSCTEWIAVA 198
Cdd:COG1173   78 ARISLLVGLLAVLIALVIGVLLGLLAGYFgGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 199 YFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSEAIPSLGRIVQK 278
Cdd:COG1173  158 RLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSE 237

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 518020310 279 NAMFMTSAPYLFIIPLAITALISISLYIVGQTLADASD 316
Cdd:COG1173  238 GRNYLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 29-319 2.86e-33

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 124.56  E-value: 2.86e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  29 ETASEHIVAPEYSYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDSMDTqninNREAWFQPPSL--QYPFGTD 106
Cdd:PRK15406  12 ENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDT----DWGMMSSAPDMesGHYFGTD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 107 DVGRNLFDEVWAGARTSLFIAFVSTAIVMSIGVVVGMFWGF-SKKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQL 185
Cdd:PRK15406  88 SSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYlGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLI 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 186 IFAMSCTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGL 265
Cdd:PRK15406 168 FVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGT 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 518020310 266 SEAIPSLGRIVQKNAMFMTSAPYLFIIPLAITALISISLYIVGQTLADASDPRN 319
Cdd:PRK15406 248 QEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKD 301
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 138-318 4.03e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.08  E-value: 4.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  138 GVVVGMFWG--FSKKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQL----IFAMSCTEWIAVAYFIRVQVMIIRDR 211
Cdd:pfam00528   1 GIPLGIIAAlrRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHgilpAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  212 EYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLqvGLSEAIPSLGRIVQKNAMFMTSAPYLFI 291
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL--GSWPGLGLLLIEAILGYDYPEIQGPVLA 158

                         170       180
                  ....*....|....*....|....*..
gi 518020310  292 IplaitALISISLYIVGQTLADASDPR 318
Cdd:pfam00528 159 A-----ALILLLLNLLVDILQRLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 120-302 2.31e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 53.05  E-value: 2.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 120 ARTSLFIAFVSTAIVMSIGVVVGMFWGFS-KKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQLIF--------AMS 190
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILpglglpalILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 191 CTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSeAIP 270
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA-PGP 159

                        170       180       190
                 ....*....|....*....|....*....|..
gi 518020310 271 SLGRIVQKNAMFMTSAPYLFIIpLAITALISI 302
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAV-ALILLLLSL 190
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 40-316 7.05e-75

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 231.16  E-value: 7.05e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  40 YSYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDsMDTQNINNReawFQPPSLQYPFGTDDVGRNLFDEVWAG 119
Cdd:COG1173    2 RSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYD-PTAQDLAAR---LQPPSAAHWLGTDQLGRDVLSRLLYG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 120 ARTSLFIAFVSTAIVMSIGVVVGMFWGFS-KKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQLIFAMSCTEWIAVA 198
Cdd:COG1173   78 ARISLLVGLLAVLIALVIGVLLGLLAGYFgGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYA 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 199 YFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSEAIPSLGRIVQK 278
Cdd:COG1173  158 RLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSE 237

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 518020310 279 NAMFMTSAPYLFIIPLAITALISISLYIVGQTLADASD 316
Cdd:COG1173  238 GRNYLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 29-319 2.86e-33

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 124.56  E-value: 2.86e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  29 ETASEHIVAPEYSYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDSMDTqninNREAWFQPPSL--QYPFGTD 106
Cdd:PRK15406  12 ENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDT----DWGMMSSAPDMesGHYFGTD 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 107 DVGRNLFDEVWAGARTSLFIAFVSTAIVMSIGVVVGMFWGF-SKKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQL 185
Cdd:PRK15406  88 SSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYlGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLI 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 186 IFAMSCTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGL 265
Cdd:PRK15406 168 FVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGT 247

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 518020310 266 SEAIPSLGRIVQKNAMFMTSAPYLFIIPLAITALISISLYIVGQTLADASDPRN 319
Cdd:PRK15406 248 QEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKD 301
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 81-321 8.78e-26

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 104.85  E-value: 8.78e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  81 SMDTQNINNREAWFQPPSLQYPFGTDDVGRNLFDEVWAGARTSLFIAFVSTAIVMSIGVVVGMFWG-FSKKLDVIM---I 156
Cdd:COG4239  101 SYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGyFGGRVDLLFqrfI 180

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 157 EVYNviaNIPFTLVVMVLAFAFGSGIWQLIFAMSCTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYL 236
Cdd:COG4239  181 EIWS---SMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNA 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 237 VSVLMTMLSRYVPMFISTEVFLSFLQVGLSEAIPSLGRIVQ--KNAMfmtSAPYLFIIPLAITALISISLYIVGQTLADA 314
Cdd:COG4239  258 MVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAqgKNNL---QAPWLGLSAFVVLALMLSLLVFIGEAVRDA 334


                 ....*..
gi 518020310 315 SDPRNHM 321
Cdd:COG4239  335 FDPRKTF 341
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 24-318 2.07e-25

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 103.27  E-value: 2.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  24 PHAVSETASEHIVAPEYSYWksvfRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDSmdtQNINNREAWFQPPSLQYPF 103
Cdd:PRK15082  10 LNAMPLVKPDQVRTPWHEFW----RRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYDA---ENYFDYDALNAGPSLQHWF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 104 GTDDVGRNLFDEVWAGARTSLFIAFVSTAIVMSIGVVVGMFWGFSKKL-DVIMIEVYNVIANIPFTLVVMVLAFAFGSGI 182
Cdd:PRK15082  83 GVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWwDRIIMRICDVLFAFPGILLAIAVVAILGSGM 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 183 WQLIFAMSCTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQ 262
Cdd:PRK15082 163 ANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLG 242

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 518020310 263 VGLSEAIPSLGRIVQKNAMFMTSAPYLFIIPLAITALISISLYIVGQTLADASDPR 318
Cdd:PRK15082 243 LGAQPPTPEWGAMLNEARADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPK 298
nikC PRK10417
nickel transporter permease NikC; Provisional
 60-317 2.67e-23

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 96.66  E-value: 2.67e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  60 MIVMITVFLFSIIHPMISGFDSMDTqninNREAWFQPPSLQYPFGTDDVGRNLFDEVWAGARTSLFIAFVSTAIVMSIGV 139
Cdd:PRK10417  10 LIIIALLALIALTSQWWLPYDPQAI----DLPSRLLSPDAQHWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 140 VVGMFWGF-SKKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQLIFAMSCTEWIAVAYFIRVQVMIIRDREYNLASQ 218
Cdd:PRK10417  86 VIGGSAGLlGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAAR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 219 TLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSEAIPSLGRIVQKNAMFMTSAPYLFIIPLAITA 298
Cdd:PRK10417 166 LSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPGLALF 245

                        250
                 ....*....|....*....
gi 518020310 299 LISISLYIVGQTLADASDP 317
Cdd:PRK10417 246 ISVMAFNLLGDALRDHLDP 264
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
26-318 4.87e-21

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 91.03  E-value: 4.87e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  26 AVSETASEHIVAPEYSYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDSmdtqNINNREAWFQPPSLQYPFGT 105
Cdd:PRK09881   3 LSEETSAVRPQKQTRFNGAKLVWMLKGSPLTVTGAVIIVLMLLMMIFSPWLATHDP----NAIDLTARLLPPSAAHWFGT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 106 DDVGRNLFDEVWAGARTSLFIAFVSTAIVMSIGVVVGMFWG-FSKKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQ 184
Cdd:PRK09881  79 DEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGvLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFN 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 185 LIFAMSCTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVG 264
Cdd:PRK09881 159 AMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLG 238

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 518020310 265 LSEAIPSLGRIVQKNAMFMTSAPYLFIIPLAITALISISLYIVGQTLADASDPR 318
Cdd:PRK09881 239 AQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAVGFNLFGDGIRDLLDPK 292
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 96-317 1.73e-18

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 84.65  E-value: 1.73e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  96 PPSLQYPFGTDDVGRNLFDEVWAGARTSLFIAFVSTAIVMSIGVVVGMFWGF-SKKLDVIMIEVYNVIANIPFTLVVMVL 174
Cdd:PRK15021 116 PPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYyGGKVDLWGQRFIEVWSGMPTLFLIILL 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 175 AFAFGSGIWQLIFAMSCTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFIST 254
Cdd:PRK15021 196 SSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITT 275

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 518020310 255 EVFLSFLQVGLSEAIPSLGRIV--QKNAMfmtSAPYLFIIP-LAITALISISLYIvGQTLADASDP 317
Cdd:PRK15021 276 LTSLDFLGFGLPLGSPSLGELLlqGKNNL---QAPWLGITAfLSVAILLSLLIFI-GEAVRDAFDP 337
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
50-318 1.89e-16

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 78.29  E-value: 1.89e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  50 FFSSKVAVAMMIVMITVFLFSIIHPMISGFDSMDtqniNNREAWFQPP------SLQYPFGTDDVGRNLFDEVWAGARTS 123
Cdd:PRK10913  26 FKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAE----QFRDALLAPPvwqeggSWAHILGTDDVGRDVLSRLMYGARLS 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 124 LFIAFVSTAIVMSIGVVVGMFWG-FSKKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQLIFAMScteWIAVAYFIR 202
Cdd:PRK10913 102 LLVGCLVVVLSLVMGVILGLIAGyFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALT---FVALPHYVR 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 203 VQ---VMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSEAIPSLGRIVQKN 279
Cdd:PRK10913 179 LTraaVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDV 258

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 518020310 280 AMFMTSAPYLFIIPLAITALISISLYIVGQTLADASDPR 318
Cdd:PRK10913 259 LQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPK 297
PRK15111 PRK15111
peptide ABC transporter permease SapC;
41-307 6.51e-12

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 65.11  E-value: 6.51e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  41 SYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFdSMDTQNINNR---EAWFQPPSLQYPFGTDDVGRNLFDEVW 117
Cdd:PRK15111  14 GTLRTAWRKFYSDALAMVGLYGCAGLALLCLFGGWLAPY-GIDQQFLGYQllpPSWSRYGEVSFFLGTDDLGRDVLSRLL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 118 AGARTSLFIAFVSTAIVMSIGVVVGMFWGFSKKL-DVIMIEVYNVIANIP-FTLVVMVLAFAfGSGIWQLIFAMscteWI 195
Cdd:PRK15111  93 SGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLrSAVLNHILDTLLSIPsLLLAIIVVAFA-GPSLSHAMFAV----WL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 196 A----VAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSEAIPS 271
Cdd:PRK15111 168 AllprMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPE 247

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 518020310 272 LGRIVQKNAMFMTSAPYLFIIPlaiTALISISLYIV 307
Cdd:PRK15111 248 WGAMLGDSLELIYVAPWTVMLP---GAAIMLSVLLV 280
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 138-318 4.03e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.08  E-value: 4.03e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  138 GVVVGMFWG--FSKKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQL----IFAMSCTEWIAVAYFIRVQVMIIRDR 211
Cdd:pfam00528   1 GIPLGIIAAlrRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHgilpAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310  212 EYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLqvGLSEAIPSLGRIVQKNAMFMTSAPYLFI 291
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFL--GSWPGLGLLLIEAILGYDYPEIQGPVLA 158

                         170       180
                  ....*....|....*....|....*..
gi 518020310  292 IplaitALISISLYIVGQTLADASDPR 318
Cdd:pfam00528 159 A-----ALILLLLNLLVDILQRLLDPR 180
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 120-302 2.31e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 53.05  E-value: 2.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 120 ARTSLFIAFVSTAIVMSIGVVVGMFWGFS-KKLDVIMIEVYNVIANIPFTLVVMVLAFAFGSGIWQLIF--------AMS 190
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKrGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILpglglpalILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518020310 191 CTEWIAVAYFIRVQVMIIRDREYNLASQTLGTSTPKIIKNNILPYLVSVLMTMLSRYVPMFISTEVFLSFLQVGLSeAIP 270
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA-PGP 159

                        170       180       190
                 ....*....|....*....|....*....|..
gi 518020310 271 SLGRIVQKNAMFMTSAPYLFIIpLAITALISI 302
Cdd:cd06261  160 GTGLLLIFAILFPGDLGVAAAV-ALILLLLSL 190
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
 41-97 5.08e-06

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 43.17  E-value: 5.08e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 518020310   41 SYWKSVFRKFFSSKVAVAMMIVMITVFLFSIIHPMISGFDsMDTQNINNReawFQPP 97
Cdd:pfam12911   1 SPWQDAWRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYD-PDQQDLSAD---LLPP 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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