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Conserved domains on  [gi|518172354|ref|WP_019342562|]
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TonB-dependent receptor [Stutzerimonas stutzeri]

Protein Classification

TonB-dependent receptor( domain architecture ID 1003665)

TonB-dependent receptor may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds

Gene Ontology:  GO:0015891

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
TonB-Xanth-Caul super family cl36973
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 35-824 0e+00

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


The actual alignment was detected with superfamily member TIGR01782:

Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 623.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354   35 MEHVEVIGQAVSIDEALKEQRNSDSVKSVVHADGIGQLPDDNAAEALQRIPGLSVERDQGEGRFVSVRGIAPDLNSVTIN 114
Cdd:TIGR01782   1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  115 GTLVPSPESGRRAVALDVLPSELVQSLSVVKTLTPDMDANSLGGTIEVESLSAFDHDGLFYSLSTEGSYDENVG--KTSP 192
Cdd:TIGR01782  81 GRTIASTDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYNDLAGkdKPGP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  193 KFSGAISNRFslgdGVDNFGVTAALSWQDRDFGSDNVETGG--KWDFEDGARLE-----EFEQRDYEITRERTGFGLNFD 265
Cdd:TIGR01782 161 RGAASYSWTF----GDGQFGVLLSASYQKRDFAEDNVETENwgTYTSADGGAQGlyfprGVRYRSYRNDRERKGVNGSLQ 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  266 YQPDDLSSYYLRTLYSRFKDTETRNAAGVEFEDAQLAGELGSAEGWR---------------ELKSREETQTIQSYVFGG 330
Cdd:TIGR01782 237 WRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTATSgalvqgtvanlqilvEARYNEEKETTTSLTLGG 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  331 ERMMGLWTLSGQVGYSEA------RERNPGGISSATFEGDFADVGFSSTTKPRLNVDPSFY-DPASFELDEVEWEETDAR 403
Cdd:TIGR01782 317 EWTGDRWTLDGDLGYSKAtrdrpdRVTRFFTAPTPGYDFDYRGGPTLTLGTPADGDDASNYtNPANGELRRTQISYQKAE 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  404 DKEKNIRLDLAREydiqGYASQFKFGGKLSRREKTNDVDIWAYDDFDDLTLADFQ-------AGNVDYALGRFGSGISAG 476
Cdd:TIGR01782 397 DSEDAAQLDATFD----GPFTSLKFGVRYRRRDKTNRGSRYRRSIIGATGASGLAgvpsdlaGAGLDGGLGGPLTGWDPA 472

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  477 ALEGLIG--GLDASAF--YDEEESRIGDFDMSEDINAAYFMNTLDLD-KWRIIAGLRYEGTEFSAKG------TGIREGE 545
Cdd:TIGR01782 473 DLDAFLNaaRGDAAGGgtYTYASTAPNTYTVTEDTTAAYAMANFDTGlRLRGNVGVRYERTDQTSDGwqsqpaANGTGSV 552

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  546 FESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVIDGD------EAEFGNPDLKPLESMNYDLG 619
Cdd:TIGR01782 553 LVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDgtggtvTVSGGNPDLKPYESDNLDLS 632

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  620 IEHYMGRAGAVSGYLFYKDIDNFIYNT---DVAGTGQWADFDQAL---SYENGSSAKLYGVELSYSQKLDWLPAPWNGVL 693
Cdd:TIGR01782 633 LEWYFGPGGLLSAAVFYKDIKNFIVTTtstETNDGGGGLVVAGVLvsrPVNGGKAGKIRGVELGYQQTFDFLPGPLSGFG 712

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  694 LGANATFSKSDADI-EGQGSRRSIDLPNHSDTVGNLMVGWENDVFNMRLAANYKSEYLAEVAGIDDEAHDLYADEQLFLD 772
Cdd:TIGR01782 713 VQANYTYVDSEADPsVDGVQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSDYLLDVGGSNINRLDRYVDPRGQLD 792

                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|..
gi 518172354  773 FKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQYEEYGPTYKLGLTLT 824
Cdd:TIGR01782 793 LSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYK 844
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 35-824 0e+00

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 623.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354   35 MEHVEVIGQAVSIDEALKEQRNSDSVKSVVHADGIGQLPDDNAAEALQRIPGLSVERDQGEGRFVSVRGIAPDLNSVTIN 114
Cdd:TIGR01782   1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  115 GTLVPSPESGRRAVALDVLPSELVQSLSVVKTLTPDMDANSLGGTIEVESLSAFDHDGLFYSLSTEGSYDENVG--KTSP 192
Cdd:TIGR01782  81 GRTIASTDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYNDLAGkdKPGP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  193 KFSGAISNRFslgdGVDNFGVTAALSWQDRDFGSDNVETGG--KWDFEDGARLE-----EFEQRDYEITRERTGFGLNFD 265
Cdd:TIGR01782 161 RGAASYSWTF----GDGQFGVLLSASYQKRDFAEDNVETENwgTYTSADGGAQGlyfprGVRYRSYRNDRERKGVNGSLQ 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  266 YQPDDLSSYYLRTLYSRFKDTETRNAAGVEFEDAQLAGELGSAEGWR---------------ELKSREETQTIQSYVFGG 330
Cdd:TIGR01782 237 WRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTATSgalvqgtvanlqilvEARYNEEKETTTSLTLGG 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  331 ERMMGLWTLSGQVGYSEA------RERNPGGISSATFEGDFADVGFSSTTKPRLNVDPSFY-DPASFELDEVEWEETDAR 403
Cdd:TIGR01782 317 EWTGDRWTLDGDLGYSKAtrdrpdRVTRFFTAPTPGYDFDYRGGPTLTLGTPADGDDASNYtNPANGELRRTQISYQKAE 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  404 DKEKNIRLDLAREydiqGYASQFKFGGKLSRREKTNDVDIWAYDDFDDLTLADFQ-------AGNVDYALGRFGSGISAG 476
Cdd:TIGR01782 397 DSEDAAQLDATFD----GPFTSLKFGVRYRRRDKTNRGSRYRRSIIGATGASGLAgvpsdlaGAGLDGGLGGPLTGWDPA 472

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  477 ALEGLIG--GLDASAF--YDEEESRIGDFDMSEDINAAYFMNTLDLD-KWRIIAGLRYEGTEFSAKG------TGIREGE 545
Cdd:TIGR01782 473 DLDAFLNaaRGDAAGGgtYTYASTAPNTYTVTEDTTAAYAMANFDTGlRLRGNVGVRYERTDQTSDGwqsqpaANGTGSV 552

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  546 FESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVIDGD------EAEFGNPDLKPLESMNYDLG 619
Cdd:TIGR01782 553 LVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDgtggtvTVSGGNPDLKPYESDNLDLS 632

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  620 IEHYMGRAGAVSGYLFYKDIDNFIYNT---DVAGTGQWADFDQAL---SYENGSSAKLYGVELSYSQKLDWLPAPWNGVL 693
Cdd:TIGR01782 633 LEWYFGPGGLLSAAVFYKDIKNFIVTTtstETNDGGGGLVVAGVLvsrPVNGGKAGKIRGVELGYQQTFDFLPGPLSGFG 712

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  694 LGANATFSKSDADI-EGQGSRRSIDLPNHSDTVGNLMVGWENDVFNMRLAANYKSEYLAEVAGIDDEAHDLYADEQLFLD 772
Cdd:TIGR01782 713 VQANYTYVDSEADPsVDGVQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSDYLLDVGGSNINRLDRYVDPRGQLD 792

                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|..
gi 518172354  773 FKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQYEEYGPTYKLGLTLT 824
Cdd:TIGR01782 793 LSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYK 844
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 62-822 4.16e-64

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 226.56  E-value: 4.16e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  62 SVVHADGIGQLPDDNAAEALQRIPGLSVERDQ-GEGRFVSVRGIAPDLNSVTINGTLVPSPESGRRaVALDVLPSELVQS 140
Cdd:cd01347    3 SVITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRG-VDLNTIPPELIER 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 141 LSVVKTLTPDM-DANSLGGTIEVESLSAFDHDGLFYSLSTeGSYDENVGKTspkfsgaisnrfslgdgvDNFGVTAALSW 219
Cdd:cd01347   82 VEVLKGPSSALyGSGAIGGVVNIITKRPTDEFGGSVTAGY-GSDNSGSSGG------------------GGFDVSGALAD 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 220 QDRDFGSdnveTGGKWDFEDGARLEEFEQRDYEitRERTGFGLNFDYQPDDLSSYYLRTLYSRFKDTETRNAAGVEFEDA 299
Cdd:cd01347  143 DGAFGAR----LYGAYRDGDGTIDGDGQADDSD--EERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGS 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 300 QLAGELGSA-EGWRELKSREETQTIQSYVFGGERMMGLWTLSGQVGYSEARERNPGGISSATFEGDFADVGFSSTTkprl 378
Cdd:cd01347  217 SLGGGPSSNtNGDRDWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYS---- 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 379 nvdpsfydpasfeldevEWEETDARDKEKNIRldlareydiqgyasqfkfggklsrrektndvdiwayddfddltlADFQ 458
Cdd:cd01347  293 -----------------SERDTTQLGFDAGLN--------------------------------------------APFG 311

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 459 AGNVDYALgrfgsgisagaleglIGGLDASafydeeesrigDFDMSEDINAAYFMNTLDL-DKWRIIAGLRYEGTEFSAK 537
Cdd:cd01347  312 TGPVAHTL---------------TLGVEYR-----------REELDEKQTALYAQDTIELtDDLTLTLGLRYDHYDQDSK 365

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 538 GTGIregefESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVIDGDeAEFGNPDLKPLESMNYD 617
Cdd:cd01347  366 DTIA-----GGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGT-AAVGNPNLKPEKSKQYE 439

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 618 LGIEHYMGRAGAVSGYLFYKDIDNFIYNTDVAgtgqwADFDQALSYENGSSAKLYGVELSYSQkldWLPAPWNgvlLGAN 697
Cdd:cd01347  440 LGLKYDPGDGLTLSAALFRIDIKNEIVSTPTN-----TGLGLVTVYVNGGKARIRGVELEASY---DLTDGLG---LTGS 508

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 698 ATFSKSDaDIEGQGSRRSIDLPNHSDTVGNLMVGWENDV--FNMRLAANYKSEYLAEVAGIDDeahDLYADEQLFLDFKA 775
Cdd:cd01347  509 YTYTDTE-VKRTDGATTGNRLPGIPKHTANLGLDYELPDegLTAGGGVRYRGKQYADTANGNN---TVKVPGYTLVDLSA 584

                        730       740       750       760
                 ....*....|....*....|....*....|....*....|....*...
gi 518172354 776 GYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQ-YEEYGPTYKLGLT 822
Cdd:cd01347  585 SYQFTKNLTLRLGVNNLFDKDYYTSLSVRGSGLYgYYGPGRTYYLSVS 632
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
35-810 2.47e-49

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 185.03  E-value: 2.47e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  35 MEHVEVIGQAVSidealKEQRNSDSVKSVVHADGIGQLPDDNAAEALQRIPGLSVERDQGEGRFVSVRGIAPDLNSV--T 112
Cdd:COG1629    1 LEEVVVTATRTD-----ESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGNRVlvL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 113 INGtlVPSPESGRRAVALDVLPSELVQSLSVVK-TLTPDMDANSLGGTIEVESLSAFDHDGLFYSLSTeGSYdenvgkts 191
Cdd:COG1629   76 VDG--VPLNDPSGGDGGLSYIDPEDIERVEVLRgPSSALYGSGALGGVINIVTKKPKDGKGGEVSASY-GSY-------- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 192 pkfsGAISNRFSLGDGVDNFGVTAALSWQDRDfgsdnvetggkwDFEDGARLEefeqrdyeitreRTGFGLNFDYQPDDL 271
Cdd:COG1629  145 ----GTYRASLSLSGGNGKLAYRLSASYRDSD------------GYRDNSDSD------------RYNLRAKLGYQLGDD 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 272 SSYYLRTLYSRFKDTETRNAAGvefedAQLAGELGSAEGWRELKSREETQTIQSYVFGG--ERMMGLWTLSGQVGYSEAR 349
Cdd:COG1629  197 TRLTLSASYSDSDQDSPGYLTL-----AALRPRGAMDDGTNPYSNDTDDNTRDRYSLSLeyEHLGDGLKLSASAYYRYDD 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 350 ERNpggissatfegdfadvgfssttkprlnvdpsFYDPASFELDEVEWEETDARDKEKNIRLDLAREYDIqGYASQFKFG 429
Cdd:COG1629  272 TDL-------------------------------DSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGF-GGKHTLLVG 319

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 430 GKLSRrektNDVDIWAYDdfddltladfqagnvdyalgrfgsgisagalegliggLDASAFYDEEESRIGDFDMSEDINA 509
Cdd:COG1629  320 LDYQR----QDLDGSGYP-------------------------------------LDLGSGSLPTLTSGADDDGTTTSLA 358

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 510 AYFMNTLDL-DKWRIIAGLRYEGTEFSAKGTGireGEFESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFE 588
Cdd:COG1629  359 LYAQDTYKLtDKLTLTAGLRYDYVSYDVDDTV---TGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFG 435

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 589 QLAPGFVidgDEAEFGNPDLKPLESMNYDLGIE-HYMGRAGAVSGYLFYKDIDNFIYNTDVAGtgqwaDFDQALSYENGS 667
Cdd:COG1629  436 ELYANGT---DPYSVGNPDLKPETSTNYELGLRyRLLDGRLSLSLALFYSDVDNEILSVPLPN-----DSGFSTYYTNAG 507

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 668 SAKLYGVELSYSQKldwlpaPWNGVLLGANATFSKS--DADIEGQGSRRSIDLPNHSDTVGNLMVGWE-NDVFNMRLAAN 744
Cdd:COG1629  508 KARSYGVELELSYQ------LTPGLSLNASYSYTDAkfDDDTDGSADLDGNRLPGVPPLTANLGLTYEfPGGWSLGLGVR 581

                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518172354 745 YKSEYLAevagidDEAHDLYADEQLFL-DFKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQY 810
Cdd:COG1629  582 YVGDRYL------DDANTQGAPGGYTLvDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 363-824 2.40e-40

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 155.31  E-value: 2.40e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  363 GDFADVGFSSTTKPRLNVDPSFYDPASFELDEVEWEETDARDKEKNIRLDLAREY-DIQGYASQFKFGGKLSRREKTNDV 441
Cdd:pfam00593  17 LGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLgDGLSWLSTLRLGLRYSSLDGDYTS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  442 DIWAYDDFDDLTLADFQAGNVDYALG-RFGSGISAGALEGLIGGLDASAFYDEEESRIGDFD-----------MSEDINA 509
Cdd:pfam00593  97 NSSGLSGAGDYLSDDRLYGLYGLDGDlELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDpanpssssysdTTTDSYG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  510 AYFMNTLDL-DKWRIIAGLRYEGTEFSAKGTGIREGEFesissDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFE 588
Cdd:pfam00593 177 LYLQDNIKLtDRLTLTLGLRYDHYSTDGDDGNGGGDNF-----SRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLG 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  589 QLAPGFVIDGDEAEF-GNPDLKPLESMNYDLGIEhYMGRAGAVSGYLFYKDIDNFIYNTDVAGTGQWADFdqalSYENGS 667
Cdd:pfam00593 252 ELYGSGSGGGGGAVAgGNPDLKPETSDNYELGLK-YDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVY----TYTNVG 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  668 SAKLYGVELSYSQKLdwlpapWNGVLLGANATFskSDADIEGQGSRRSIDLPNHSDTVGNLMVGWENDVFNMRLAANYKS 747
Cdd:pfam00593 327 KARIRGVELELSGRL------WGLGLSGGGYTY--TDADDDADADDTGNPLPNVPRHTANLGLTYDFPLGGWGARLGARY 398

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 518172354  748 EYLAEVAgIDDEAHDLYADEQLFLDFKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQ-YEEYGPTYKLGLTLT 824
Cdd:pfam00593 399 VGSGERR-YGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGgYPGPGRTFYLGLSYK 475
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 519-821 6.99e-13

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 72.22  E-value: 6.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 519 DKWRIIAGLryegtefsAKGTGIREGEFESISsdnryDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVID- 597
Cdd:PRK10064 368 DEWRIFEPL--------ALTTGVRMDDHETYG-----DHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNs 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 598 --GDEAEFGNPDLKPLESMNYDLGIeHYMGRAGAVSGY-----LFYKDIDNFIyntDVAGTgqwADFDQA---------- 660
Cdd:PRK10064 435 crGACKIVGSPDLKPETSESWELGL-YYMGEEGWLEGVessvtVFRNDVDDRI---SISRT---SDVNAApgyqnfvgfe 507

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 661 ----------LSYENGSSAKLYGVELSYSQKLDwlpAPWNgvlLGANATFSKSdADIEGQGSRRSIDLPNHSdtvGNLMV 730
Cdd:PRK10064 508 tngrgrrvpvFRYYNVNKARIQGVETELKIPFN---DEWK---LSLNYTYNDG-RDVSNGENKPLSDLPFHT---ANGTL 577

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 731 GWENDV---FNMRLAANYKSEYLAevagidDEAHDLYADEQLFLDFKAGYFITPNLQLTVEALNLTNESyfvyTGRSHYn 807
Cdd:PRK10064 578 DWKPLAledWSFYVSGNYTGQKRA------DSATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKD----LSRDDY- 646

                        330
                 ....*....|....
gi 518172354 808 aQYEEYGPTYKLGL 821
Cdd:PRK10064 647 -SYNEDGRRYFMAV 659
 
Name Accession Description Interval E-value
TonB-Xanth-Caul TIGR01782
TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane ...
 35-824 0e+00

TonB-dependent receptor; This model represents a family of TonB-dependent outer-membrane receptors which are found mainly in Xanthomonas and Caulobacter. These appear to represent the expansion of a paralogous family in that the 22 X. axonopodis (21 in X. campestris) and 18 C. crescentus sequences are more closely related to each other than any of the many TonB-dependent receptors found in other species. In fact, the Crescentus and Xanthomonas sequences are inseparable on a phylogenetic tree using a PAM-weighted neighbor-joining method, indicating that one of the two genuses may have acquired this set of receptors from the other. The mechanism by which this family is shared between Xanthomonas, a gamma proteobacterial plant pathogen and Caulobacter, an alpha proteobacterial aquatic organism is unclear. [Transport and binding proteins, Porins]


Pssm-ID: 273804 [Multi-domain]  Cd Length: 845  Bit Score: 623.59  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354   35 MEHVEVIGQAVSIDEALKEQRNSDSVKSVVHADGIGQLPDDNAAEALQRIPGLSVERDQGEGRFVSVRGIAPDLNSVTIN 114
Cdd:TIGR01782   1 LDAVQVTGQRASLEKAIDAKRDADSVVDVISAEDIGKLPDVNVAEALQRVPGVSIERDQGEGRYVSVRGLGPSYNRTTLN 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  115 GTLVPSPESGRRAVALDVLPSELVQSLSVVKTLTPDMDANSLGGTIEVESLSAFDHDGLFYSLSTEGSYDENVG--KTSP 192
Cdd:TIGR01782  81 GRTIASTDSGGRAFSLDLLPSELVSGVEVYKTPTADMDEGGIGGTVDLRTRSPFDYDGRTLSGSAQGGYNDLAGkdKPGP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  193 KFSGAISNRFslgdGVDNFGVTAALSWQDRDFGSDNVETGG--KWDFEDGARLE-----EFEQRDYEITRERTGFGLNFD 265
Cdd:TIGR01782 161 RGAASYSWTF----GDGQFGVLLSASYQKRDFAEDNVETENwgTYTSADGGAQGlyfprGVRYRSYRNDRERKGVNGSLQ 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  266 YQPDDLSSYYLRTLYSRFKDTETRNAAGVEFEDAQLAGELGSAEGWR---------------ELKSREETQTIQSYVFGG 330
Cdd:TIGR01782 237 WRPSDALELYLDTLYSKYDDDETRQQIEFRTLNGGSTVITSNQTATSgalvqgtvanlqilvEARYNEEKETTTSLTLGG 316

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  331 ERMMGLWTLSGQVGYSEA------RERNPGGISSATFEGDFADVGFSSTTKPRLNVDPSFY-DPASFELDEVEWEETDAR 403
Cdd:TIGR01782 317 EWTGDRWTLDGDLGYSKAtrdrpdRVTRFFTAPTPGYDFDYRGGPTLTLGTPADGDDASNYtNPANGELRRTQISYQKAE 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  404 DKEKNIRLDLAREydiqGYASQFKFGGKLSRREKTNDVDIWAYDDFDDLTLADFQ-------AGNVDYALGRFGSGISAG 476
Cdd:TIGR01782 397 DSEDAAQLDATFD----GPFTSLKFGVRYRRRDKTNRGSRYRRSIIGATGASGLAgvpsdlaGAGLDGGLGGPLTGWDPA 472

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  477 ALEGLIG--GLDASAF--YDEEESRIGDFDMSEDINAAYFMNTLDLD-KWRIIAGLRYEGTEFSAKG------TGIREGE 545
Cdd:TIGR01782 473 DLDAFLNaaRGDAAGGgtYTYASTAPNTYTVTEDTTAAYAMANFDTGlRLRGNVGVRYERTDQTSDGwqsqpaANGTGSV 552

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  546 FESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVIDGD------EAEFGNPDLKPLESMNYDLG 619
Cdd:TIGR01782 553 LVPVSADRDYTDVLPSLNLAYDLTDDLVLRFAASKTITRPDFGDLAANTSLSDDgtggtvTVSGGNPDLKPYESDNLDLS 632

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  620 IEHYMGRAGAVSGYLFYKDIDNFIYNT---DVAGTGQWADFDQAL---SYENGSSAKLYGVELSYSQKLDWLPAPWNGVL 693
Cdd:TIGR01782 633 LEWYFGPGGLLSAAVFYKDIKNFIVTTtstETNDGGGGLVVAGVLvsrPVNGGKAGKIRGVELGYQQTFDFLPGPLSGFG 712

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  694 LGANATFSKSDADI-EGQGSRRSIDLPNHSDTVGNLMVGWENDVFNMRLAANYKSEYLAEVAGIDDEAHDLYADEQLFLD 772
Cdd:TIGR01782 713 VQANYTYVDSEADPsVDGVQRRKLPLPGLSKNTANATLYYEKGGFSARLSYNYRSDYLLDVGGSNINRLDRYVDPRGQLD 792

                         810       820       830       840       850
                  ....*....|....*....|....*....|....*....|....*....|..
gi 518172354  773 FKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQYEEYGPTYKLGLTLT 824
Cdd:TIGR01782 793 LSASYQVSDHLSLGLQASNLTNEPSRWYTGGKQRPREYVETGRTYMLGLRYK 844
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 62-822 4.16e-64

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 226.56  E-value: 4.16e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  62 SVVHADGIGQLPDDNAAEALQRIPGLSVERDQ-GEGRFVSVRGIAPDLNSVTINGTLVPSPESGRRaVALDVLPSELVQS 140
Cdd:cd01347    3 SVITAEDIEKQPATSLADLLRRIPGVSVTRGGgGGGSTISIRGFGPDRTLVLVDGLPLASSNYGRG-VDLNTIPPELIER 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 141 LSVVKTLTPDM-DANSLGGTIEVESLSAFDHDGLFYSLSTeGSYDENVGKTspkfsgaisnrfslgdgvDNFGVTAALSW 219
Cdd:cd01347   82 VEVLKGPSSALyGSGAIGGVVNIITKRPTDEFGGSVTAGY-GSDNSGSSGG------------------GGFDVSGALAD 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 220 QDRDFGSdnveTGGKWDFEDGARLEEFEQRDYEitRERTGFGLNFDYQPDDLSSYYLRTLYSRFKDTETRNAAGVEFEDA 299
Cdd:cd01347  143 DGAFGAR----LYGAYRDGDGTIDGDGQADDSD--EERYNVAGKLDWRPDDDTRLTLDAGYQDQDADGPGGTLPANGTGS 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 300 QLAGELGSA-EGWRELKSREETQTIQSYVFGGERMMGLWTLSGQVGYSEARERNPGGISSATFEGDFADVGFSSTTkprl 378
Cdd:cd01347  217 SLGGGPSSNtNGDRDWDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYS---- 292

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 379 nvdpsfydpasfeldevEWEETDARDKEKNIRldlareydiqgyasqfkfggklsrrektndvdiwayddfddltlADFQ 458
Cdd:cd01347  293 -----------------SERDTTQLGFDAGLN--------------------------------------------APFG 311

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 459 AGNVDYALgrfgsgisagaleglIGGLDASafydeeesrigDFDMSEDINAAYFMNTLDL-DKWRIIAGLRYEGTEFSAK 537
Cdd:cd01347  312 TGPVAHTL---------------TLGVEYR-----------REELDEKQTALYAQDTIELtDDLTLTLGLRYDHYDQDSK 365

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 538 GTGIregefESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVIDGDeAEFGNPDLKPLESMNYD 617
Cdd:cd01347  366 DTIA-----GGTTAKKSYSHWSPSLGLVYKLTDGLSLYASYSQGFRAPSLGELYGGGSHGGT-AAVGNPNLKPEKSKQYE 439

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 618 LGIEHYMGRAGAVSGYLFYKDIDNFIYNTDVAgtgqwADFDQALSYENGSSAKLYGVELSYSQkldWLPAPWNgvlLGAN 697
Cdd:cd01347  440 LGLKYDPGDGLTLSAALFRIDIKNEIVSTPTN-----TGLGLVTVYVNGGKARIRGVELEASY---DLTDGLG---LTGS 508

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 698 ATFSKSDaDIEGQGSRRSIDLPNHSDTVGNLMVGWENDV--FNMRLAANYKSEYLAEVAGIDDeahDLYADEQLFLDFKA 775
Cdd:cd01347  509 YTYTDTE-VKRTDGATTGNRLPGIPKHTANLGLDYELPDegLTAGGGVRYRGKQYADTANGNN---TVKVPGYTLVDLSA 584

                        730       740       750       760
                 ....*....|....*....|....*....|....*....|....*...
gi 518172354 776 GYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQ-YEEYGPTYKLGLT 822
Cdd:cd01347  585 SYQFTKNLTLRLGVNNLFDKDYYTSLSVRGSGLYgYYGPGRTYYLSVS 632
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
35-810 2.47e-49

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 185.03  E-value: 2.47e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  35 MEHVEVIGQAVSidealKEQRNSDSVKSVVHADGIGQLPDDNAAEALQRIPGLSVERDQGEGRFVSVRGIAPDLNSV--T 112
Cdd:COG1629    1 LEEVVVTATRTD-----ESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFGGGGNRVlvL 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 113 INGtlVPSPESGRRAVALDVLPSELVQSLSVVK-TLTPDMDANSLGGTIEVESLSAFDHDGLFYSLSTeGSYdenvgkts 191
Cdd:COG1629   76 VDG--VPLNDPSGGDGGLSYIDPEDIERVEVLRgPSSALYGSGALGGVINIVTKKPKDGKGGEVSASY-GSY-------- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 192 pkfsGAISNRFSLGDGVDNFGVTAALSWQDRDfgsdnvetggkwDFEDGARLEefeqrdyeitreRTGFGLNFDYQPDDL 271
Cdd:COG1629  145 ----GTYRASLSLSGGNGKLAYRLSASYRDSD------------GYRDNSDSD------------RYNLRAKLGYQLGDD 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 272 SSYYLRTLYSRFKDTETRNAAGvefedAQLAGELGSAEGWRELKSREETQTIQSYVFGG--ERMMGLWTLSGQVGYSEAR 349
Cdd:COG1629  197 TRLTLSASYSDSDQDSPGYLTL-----AALRPRGAMDDGTNPYSNDTDDNTRDRYSLSLeyEHLGDGLKLSASAYYRYDD 271

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 350 ERNpggissatfegdfadvgfssttkprlnvdpsFYDPASFELDEVEWEETDARDKEKNIRLDLAREYDIqGYASQFKFG 429
Cdd:COG1629  272 TDL-------------------------------DSDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGF-GGKHTLLVG 319

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 430 GKLSRrektNDVDIWAYDdfddltladfqagnvdyalgrfgsgisagalegliggLDASAFYDEEESRIGDFDMSEDINA 509
Cdd:COG1629  320 LDYQR----QDLDGSGYP-------------------------------------LDLGSGSLPTLTSGADDDGTTTSLA 358

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 510 AYFMNTLDL-DKWRIIAGLRYEGTEFSAKGTGireGEFESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFE 588
Cdd:COG1629  359 LYAQDTYKLtDKLTLTAGLRYDYVSYDVDDTV---TGTDSASGSRSYSAFSPSLGLTYQLSPNLSLYASYSRGFRAPTFG 435

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 589 QLAPGFVidgDEAEFGNPDLKPLESMNYDLGIE-HYMGRAGAVSGYLFYKDIDNFIYNTDVAGtgqwaDFDQALSYENGS 667
Cdd:COG1629  436 ELYANGT---DPYSVGNPDLKPETSTNYELGLRyRLLDGRLSLSLALFYSDVDNEILSVPLPN-----DSGFSTYYTNAG 507

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 668 SAKLYGVELSYSQKldwlpaPWNGVLLGANATFSKS--DADIEGQGSRRSIDLPNHSDTVGNLMVGWE-NDVFNMRLAAN 744
Cdd:COG1629  508 KARSYGVELELSYQ------LTPGLSLNASYSYTDAkfDDDTDGSADLDGNRLPGVPPLTANLGLTYEfPGGWSLGLGVR 581

                        730       740       750       760       770       780
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518172354 745 YKSEYLAevagidDEAHDLYADEQLFL-DFKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQY 810
Cdd:COG1629  582 YVGDRYL------DDANTQGAPGGYTLvDLGAGYRFGDNLTLSLGVDNLFDKKYATSLSVRASNVRG 642
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 15-786 1.56e-47

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 179.28  E-value: 1.56e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  15 ISLLALAVSAGSAWAEEPLVMEHVEVIGQAVSidealKEQRNSDSVKSVVHADGIGQLPDDNAAEALQRIPGLSVERDQG 94
Cdd:COG4771    7 LLLLALAAQAADALAEDATELEEVVVTATRTE-----QSLSDAPASVSVITAEEIEKLGATDLADALRLLPGVSVTRSGG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  95 EGRF--VSVRGIAPDLNSVTINGTLVPSPESGRRaVALDVLPSELVQSLSVVKTLTPDM-DANSLGGTIEVESLSAFDHD 171
Cdd:COG4771   82 RGGSsgISIRGLGGDRVLVLIDGVPVNNPALGGG-GDLSYIPPDDIERIEVIRGPASALyGSDAIGGVINIITKKPTDEL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 172 GLFYSLSTeGSYDEnvgktspkfsGAISNRFSLGDGVDNFGVTAALSWQDRDFGSDNVETGGKWDFEdgarleefeqrdy 251
Cdd:COG4771  161 EGSVSLGY-GSNGN----------GTYSGSLSLGGPGDKLSFLLSGSYRDRDGYLDYRNGGFVGNSG------------- 216

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 252 eitRERTGFGLNFDYQPDDLSSYYLRTLYSRFKDTETRNAAGVEFEDAQLAGElgsaegwrelksREETQTIQSYVFGGE 331
Cdd:COG4771  217 ---YERYNLNAKLGYRLSDNHRLSLSGGYSRQDRDGGPPTLGDTEISSDNAGD------------RDTTTDRGNYSLRYN 281

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 332 RMMGlWTLSGQVGYSEARERNPGGISSATFEGDfadvgfssttkprlnvdpsfydpasfeldeveweeTDARDKEKNIRL 411
Cdd:COG4771  282 GDLG-DNLDLSLYYSRTDRDSTNGSLGGSTGSF-----------------------------------SDSDDTTYGLEL 325

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 412 DLareydiqgyasQFKFGGKLSrrektndvdiwayddfddltladfqagnvdyalgrfgsgisagalegLIGGLDASAFY 491
Cdd:COG4771  326 DL-----------TYPLGGNHT-----------------------------------------------LTLGAEYRYDD 347

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 492 DEEESRIGDFDMSEDINAAYFMNTLDL-DKWRIIAGLRYEGTefsakgtgiregefeSISSDNRYDHWLPGLHVRYQLTD 570
Cdd:COG4771  348 LDSSSFLGGADASRDTYGLFAQDEWKLtDKLTLTAGLRYDYY---------------STFGASNYTAFSPRLGLRYDLSD 412

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 571 DTQLRAAWTNTVVRPTFEQLAPGFVIDGDEAEFGNPDLKPLESMNYDLGIEHYMGRAGA-VSGYLFYKDIDNFIYNTDVA 649
Cdd:COG4771  413 NLTLRASYGRGFRAPSLAELYGSGTGTPGRYVLGNPDLKPETSDNYELGLEYRLGNGGLsLSLTGFYTDIKDLIVLVPVG 492

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 650 GTGqwadfDQALSYENGSSAKLYGVELSYSQKLDwlpapwNGVLLGANATFSKSDADiEGQGSRRSIDLPNHSdtvGNLM 729
Cdd:COG4771  493 PGP-----GDVLQYENVGKARTYGLELELKYRLG------KGLTLTASYTYLDSKID-DGDTGEPLPNVPPHK---ANLG 557

                        730       740       750       760       770
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 518172354 730 VGWE--NDVFNMRLAANYKSEYLAEVAGIDDEAHDLYadeqLFLDFKAGYFITPNLQLT 786
Cdd:COG4771  558 LDYRlpKWWLLLLLTRYYGGRYVTPPSGRLEGYTPGY----TLLDLRASYKLTKNLTLS 612
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 363-824 2.40e-40

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 155.31  E-value: 2.40e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  363 GDFADVGFSSTTKPRLNVDPSFYDPASFELDEVEWEETDARDKEKNIRLDLAREY-DIQGYASQFKFGGKLSRREKTNDV 441
Cdd:pfam00593  17 LGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLgDGLSWLSTLRLGLRYSSLDGDYTS 96

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  442 DIWAYDDFDDLTLADFQAGNVDYALG-RFGSGISAGALEGLIGGLDASAFYDEEESRIGDFD-----------MSEDINA 509
Cdd:pfam00593  97 NSSGLSGAGDYLSDDRLYGLYGLDGDlELSLDLSHDLLLGVELRTAGLDYRRLDDDAYDPYDpanpssssysdTTTDSYG 176

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  510 AYFMNTLDL-DKWRIIAGLRYEGTEFSAKGTGIREGEFesissDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFE 588
Cdd:pfam00593 177 LYLQDNIKLtDRLTLTLGLRYDHYSTDGDDGNGGGDNF-----SRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRAPSLG 251

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  589 QLAPGFVIDGDEAEF-GNPDLKPLESMNYDLGIEhYMGRAGAVSGYLFYKDIDNFIYNTDVAGTGQWADFdqalSYENGS 667
Cdd:pfam00593 252 ELYGSGSGGGGGAVAgGNPDLKPETSDNYELGLK-YDDGRLSLSLALFYIDIKNLITSDPDGPGLGGTVY----TYTNVG 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  668 SAKLYGVELSYSQKLdwlpapWNGVLLGANATFskSDADIEGQGSRRSIDLPNHSDTVGNLMVGWENDVFNMRLAANYKS 747
Cdd:pfam00593 327 KARIRGVELELSGRL------WGLGLSGGGYTY--TDADDDADADDTGNPLPNVPRHTANLGLTYDFPLGGWGARLGARY 398

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 518172354  748 EYLAEVAgIDDEAHDLYADEQLFLDFKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAQ-YEEYGPTYKLGLTLT 824
Cdd:pfam00593 399 VGSGERR-YGDAANTFKTPGYTLVDLSAGYRLNKNLTLRLGVNNLFDKYYKRYYSSGGGNLGgYPGPGRTFYLGLSYK 475
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
14-799 1.15e-29

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 125.81  E-value: 1.15e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  14 RISLLALAVSAGSAWAEEPLVMEHVEVIGQAVSIDEAlkeQRNSDSVkSVVHADGIGQLPDDNAAEALQRIPGLSVERDQ 93
Cdd:COG4772    2 RRALAAALLLAAAAAAEAATTLETVVVTGSRAAEARL---KDVPGSV-SVVDREELENQAATSLREVLRRVPGVNVQEED 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  94 GEGRF--VSVRGIAPDLNS-VTI--NGTLVPSPESGrrAVALDVLPS-ELVQSLSVVK-----TLTPdmdaNSLGGTIEV 162
Cdd:COG4772   78 GFGLRpnIGIRGLGPRRSRgITLleDGIPIAPAPYG--DPAAYYFPDlERMERIEVLRgaaalRYGP----QTVGGAINF 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 163 ESLSAFDHDGLFYSLSTeGSYdenvgktspkfsGAISNRFSLGDGVDNFGVTAALSWQDRDfgsdnvetggkwDFEDGAR 242
Cdd:COG4772  152 VTRTIPTAFGGELRVTG-GSF------------GYRRTHASVGGTVGNFGYLVEYSRKRGD------------GFRDNSG 206

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 243 LEefeqrdyeitreRTGFGLNFDYQPDDLSSYYLRTLYSRfkdtetrnaagvefEDAQLAGELGSAEgWRElksrEETQT 322
Cdd:COG4772  207 FD------------INDFNAKLGYRLSDRQELTLKFQYYD--------------EDANTPGGLTDAQ-FDA----DPRQS 255

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 323 IQSYV-FGGER-MMGL---WTLSGQV-----GYSEARERNpggissATFEGDFADvgfssttkPRLNVDPSFYDPASFEL 392
Cdd:COG4772  256 YRPADqFDTRRtQLSLryeHQLSDNTtltttAYYNDFSRN------WYIRQNTAD--------PNTPGLGLRGNPRGYRS 321

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 393 DEVEweetdardkeknirLDLAREYDIQGYASQFKFGGKLSRrektndvdiwayDDFDDltladfQAGNVDYALGRFGSG 472
Cdd:COG4772  322 YGIE--------------PRLTHRFELGGVPHTLEVGLRYHR------------EEEDR------KQYVNTYGQGRSGAG 369

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 473 ISAgalegliggldasafydeeesrigDFDMSEDINAAYFMNTLDL-DKWRIIAGLRYEGTEFSAKGTGIReGEFESISS 551
Cdd:COG4772  370 LRR------------------------DRRFSADALAAYAQNRFELtGRLTLTPGLRYEHIRRDRTDRYST-RTGGDDSG 424

                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 552 DNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFvidgdeaeFGNPDLKPLESMNYDLGIEHYMGRAGAVS 631
Cdd:COG4772  425 SNSYSEFLPGLGLLYQLTDNLQLYANVSRGFEPPTFGDLAYGN--------GGNPDLKPEKSWNYELGTRGRIGNGLSAE 496

                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 632 GYLFYKDIDNFIYNTDVAGtgqwadfDQALSYENGSSAKLYGVELSYSqkLDWLPAPWNGVLLGANATFSKS------DA 705
Cdd:COG4772  497 VALFYIDYDNELGSCSAAG-------GDRSTFTNAGETRHQGLELALD--YDLLKGGGLGLPLFAAYTYTDAeftsdfGP 567

                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 706 DIEGQgsrrsiDLPNHSDTVGNLMVGWENDVFNMRLAANYKSEYLAEVAGIDDEAHDLYADEQLFLDFKAGYFITPNLQL 785
Cdd:COG4772  568 VFAGN------RLPYVPRHQLTAGLGYEHGGWTANLNGRYVSEQFTDAANTVADGSFGKIPSYTVLDLSASYDFGKNLSL 641

                        810
                 ....*....|....
gi 518172354 786 TVEALNLTNESYFV 799
Cdd:COG4772  642 FAGVNNLFDKRYIA 655
OMP_b-brl_3 pfam14905
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ...
 491-709 7.32e-20

Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.


Pssm-ID: 434300 [Multi-domain]  Cd Length: 407  Bit Score: 92.72  E-value: 7.32e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  491 YDEEESRIGDFDMSEDINAAYFMNTLDLDKWRIIAGLRYEGTEFsakgtgirEGEFESISS--DNRYDHWLPGLHVRYQL 568
Cdd:pfam14905  98 WVPDPSRSNDFDYKENIYAAYASYSKKFGKWSYQAGLRAEYTDI--------DGDSVTTNEtfKRNYFNLFPSASLSYKL 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  569 TDDTQLRAAWTNT--VVRPTFEQLAPgFVIDGDE--AEFGNPDLKPLESMNYDLGIEhYMGRAGAVSGYLFYKDIDNFIY 644
Cdd:pfam14905 170 NDNNSLQLSLYYRriINRPSYWDLNP-FRNYSDPynYSQGNPNLKPEYTNSFELGYT-YKWKLSLSLSYRYTNDVIQQTF 247

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 518172354  645 NTDVAGTGQWadfdqaLSYENGSSAKLYGVELSYSQKL-DWlpapWNgvlLGANATFSKSDADIEG 709
Cdd:pfam14905 248 ITDDNDNVTY------TTYENLGKSNSYGLELSASFNPtKW----WS---LNGNLNGYYNKYKIDG 300
TonB-hemlactrns TIGR01786
TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model ...
 61-822 4.54e-17

TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273808 [Multi-domain]  Cd Length: 715  Bit Score: 85.93  E-value: 4.54e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354   61 KSVVHADGIGQLPDDNAAEALQRIPGLSVerdQGEGRF----VSVRGIAPDLNSVTINGtlVPSPES----GRRAVALDV 132
Cdd:TIGR01786  25 VSVISREQLKSQQVRNLRDLLRYEPGVSV---VEGGRGgsqgINIRGLDKNRVAVLVDG--IRQNTSyggqGSTFYAINS 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  133 LPSELVQSLSVVKTLTPDM-DANSLGGTIEVESLSAFDhdglfysLSTEGsydENVG---KTSpkfSGAISNRF--SLGD 206
Cdd:TIGR01786 100 IDPELIKSIEIVKGASSSLyGSGALGGVVAFRTKDAAD-------LLKPG---KDLGglsKLG---YSSANNRFtqSVAA 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  207 GVDNFGVTAALSWQDRDFGsdNVETGGKWDFEDGARLEEFEQRDYEITrertGFGLNFDYQPDDlsSYYLRTLYSRFKDT 286
Cdd:TIGR01786 167 AGRNDDVDALVQATYRRGH--ELKNGNKANIGNESKRSKPNPSDYKSQ----SFLAKLGWQLND--AHRLGLSLEYTQTD 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  287 ETRnaagvefedaqlagelgsaegwrelksREETQTIQSYVFGGERMMGLWtlsgqvgYSEARERNPGGISSATFEgdfa 366
Cdd:TIGR01786 239 YDE---------------------------PEMTNTSYLTKPLGAPLLSST-------VVLGDSKTRDRRTGLDYE---- 280

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  367 dvgfssttkprLNVDPSFYDPASFELDeveWEETDARDKEKNIRLDLAREYDIQGyasqfkfggklSRREKTND----VD 442
Cdd:TIGR01786 281 -----------LNPDNSWLDTVKLALD---KQYIQLYNYLNATSASDYPGVDKNG-----------RYKDKYDYytlgFD 335

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  443 IWAYDDFDDLTLadfqagNVDYALGRFGSGISAG-ALEGLIGGLDASAFYDEEESRIGDFDMSEDINAAYFMNtldlDKW 521
Cdd:TIGR01786 336 TNNKIEFSVHSL------SLTYGLDRFKDKVSTGdSRRNLPTAAYNLYGYEGENRPVKGSNFGLFLQDNIKLG----DWL 405

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  522 RIIAGLRYEGTEFSAKGTGIREgefeSISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVIDGDEA 601
Cdd:TIGR01786 406 SLSAGLRYDHYKTDPKADESKD----YGAISKTYSRWSPSLGLTYKPTPWLTLYYSYSQGFRAPSFDELYGTGAHPGGGP 481

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  602 EF--GNPDLKPLESMNYDLGIEhYMGRAGAVSGYLFYKDIDNFIYNTDVAGTGQWADFDQAL---SYENGSSAKLYGVEL 676
Cdd:TIGR01786 482 YTflPNPNLKPETSKNWEIGIN-LHFDQLDFKVSYFRNDYKDFIDLGIGVTAKGNMAQVGSNtitNYVNIDNARIRGIEL 560

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  677 sySQKLDWlpAPWNGVLLGANATFSKSDADIEGQGSRRSIDLPNHSDTVgnlmVGWENDVFNMRLAANYKSEYLA---EV 753
Cdd:TIGR01786 561 --SGRYDL--GSFFSGPDGWTTTLKYGYTKGKDSDTNPWLNAITPLKVV----LGLGYDHPDEKWGVGLTLTFSGakdAV 632

                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  754 AGIDDEAHDLYADEQLFL--------DFKAGYFITPNLQLTVEALNLTNESYFVYTG-RSHYNAQYEEYGP--TYKLGLT 822
Cdd:TIGR01786 633 DAYATYYENGEAAKAGPLrtpsytvvDLYGYYKPNKNLTLRFGVYNLLDRKYTTWESaRQAGPLATGYTAPgrNYKASVE 712
TonB-hemin TIGR01785
TonB-dependent heme/hemoglobin receptor family protein; This model represents the ...
 62-822 7.58e-15

TonB-dependent heme/hemoglobin receptor family protein; This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273807 [Multi-domain]  Cd Length: 665  Bit Score: 78.59  E-value: 7.58e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354   62 SVVHADGIGQLPDDNAAEALQRIPGLSVerdQGEGRF----VSVRGIAPDLNSVTINGtlVPSP-ESGRRAVALDVLPSE 136
Cdd:TIGR01785  23 SVISGEQIESKQANNLADALNTVPGVDV---TGGGRPpgqsINIRGLQDNRVLVVVDG--ARQNyQRGGAHNGSLFVDPE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  137 LVQSLSVVKTLTPDM-DANSLGGTIEVESLSAFD--HDGLFYSLSTEGSYDENvgKTSPKFSGAISNRFslGDGVDnfGV 213
Cdd:TIGR01785  98 LLKRIEIVKGPSSSLyGSGALGGVVAFRTKDAADllRPGQLFGGLAKLSYGSN--NNSFGGSVAVAGRL--DDNLD--AL 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  214 TAALSWqdrdfGSDNVETGGKWDFEDgarlEEFEQRDyeitrertgFGLNFDYQPDDLSSYYLRTLYSRFKDTETRNAAG 293
Cdd:TIGR01785 172 VAATYR-----DGGNYRNGNKEEATN----SAYVQKN---------LLAKLGWQLDDAQRLEFSYFTTEGSLDEAQNSGP 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  294 vefedaQLAGELGSAEGWRELKSREETQTIQSYVFGGERmmGLWTLSGQVGYSEARERN-----PGGISSATfegDFADV 368
Cdd:TIGR01785 234 ------GTEYVLGSSSTLLASSTRDRSATLTYNWTPEDN--PWLDATASLYYNRTENDNdrsarGVGREEGY---QYTTY 302

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  369 GFSSTTKPRLNVDpsfyDPASFELDeVEWeetdardkeknirldlaREYDIQGYasqfkfggklsrREKTNDVDIWAYDD 448
Cdd:TIGR01785 303 GATLQNTSRFDVA----SWSTLTYG-VDW-----------------MKDKRRTE------------SFDPNSVTTIVPNP 348

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  449 FDdltladfqagnvdyALGRFgsgisagalegliggldaSAFYDEEESRIGDfdmsedinaayfmntldlDKWRIIAGLR 528
Cdd:TIGR01785 349 PS--------------AKEYF------------------FGLFLQDNIPLLD------------------DRLTLSAGLR 378

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  529 YEGTEFSAKGTgiregeFESISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLA---PGFVIDGDEAEFGN 605
Cdd:TIGR01785 379 YDHYKLSPKTT------ADTEAVDRSYSRWSPSLGLSYKPVDWLTLYASYSQGFRAPSIDELYgtgDHPGTPGGYTFAPN 452

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  606 PDLKPLESMNYDLGIEHYMGR--------AGAVSgyLFYKDIDNFIYNTDVAGTGQWADFDQALSYENGSSAKLYGVELS 677
Cdd:TIGR01785 453 PNLKPETSKTWELGANLSFDNllldndqlQFKVA--YFYNDVKDFIDLTIGVTDNVTAGMNNITQYVNIDGARIRGIEAS 530

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  678 YSQKLDWLpapWNGVLLGAnatfsksdadIEGQGSRRSIDLPNHSDTVGNLMVGWenDVFNMRLAANYKSEYLA--EVAG 755
Cdd:TIGR01785 531 ASYDAGLW---ATGLSYGY----------TIGKDQNTNQWLSNIPPLKLVVTVGY--RFPDRRLDLGAKAAYYErqSESP 595

                         730       740       750       760       770       780       790
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518172354  756 IDDEA---HDLYADEQLFLDFKAGYFITPNLQLTVEAL--NLTNESYFVYTGrshynAQYEEYGPTYKLGLT 822
Cdd:TIGR01785 596 TTEDVaanGLLTTPGYTVVDLYATYQPNAVKGLTVRFGvnNLTDRKYTPAQS-----VPGAGPGRNFKGSVK 662
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 53-159 7.89e-15

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 71.15  E-value: 7.89e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354   53 EQRNSDSVKSVVHADGIGQLPDDNAAEALQRIPGLSV-ERDQGEGRFVSVRGIAPDLNSVTINGtlVPSPESGRRAVALD 131
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVsSGGGGGGSSISIRGFGSNRVLVLVDG--VPLNSGGGGSVDLN 78

                          90       100
                  ....*....|....*....|....*....
gi 518172354  132 VLPSELVQSLSVVK-TLTPDMDANSLGGT 159
Cdd:pfam07715  79 SIDPEDIERVEVLKgPASALYGSGAIGGV 107
PRK10064 PRK10064
catecholate siderophore receptor CirA; Provisional
 519-821 6.99e-13

catecholate siderophore receptor CirA; Provisional


Pssm-ID: 236646 [Multi-domain]  Cd Length: 663  Bit Score: 72.22  E-value: 6.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 519 DKWRIIAGLryegtefsAKGTGIREGEFESISsdnryDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGFVID- 597
Cdd:PRK10064 368 DEWRIFEPL--------ALTTGVRMDDHETYG-----DHWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNs 434

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 598 --GDEAEFGNPDLKPLESMNYDLGIeHYMGRAGAVSGY-----LFYKDIDNFIyntDVAGTgqwADFDQA---------- 660
Cdd:PRK10064 435 crGACKIVGSPDLKPETSESWELGL-YYMGEEGWLEGVessvtVFRNDVDDRI---SISRT---SDVNAApgyqnfvgfe 507

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 661 ----------LSYENGSSAKLYGVELSYSQKLDwlpAPWNgvlLGANATFSKSdADIEGQGSRRSIDLPNHSdtvGNLMV 730
Cdd:PRK10064 508 tngrgrrvpvFRYYNVNKARIQGVETELKIPFN---DEWK---LSLNYTYNDG-RDVSNGENKPLSDLPFHT---ANGTL 577

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 731 GWENDV---FNMRLAANYKSEYLAevagidDEAHDLYADEQLFLDFKAGYFITPNLQLTVEALNLTNESyfvyTGRSHYn 807
Cdd:PRK10064 578 DWKPLAledWSFYVSGNYTGQKRA------DSATAKTPGGYTIWNTGAAWQVTKDVKLRAGVLNLGDKD----LSRDDY- 646

                        330
                 ....*....|....
gi 518172354 808 aQYEEYGPTYKLGL 821
Cdd:PRK10064 647 -SYNEDGRRYFMAV 659
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
509-824 1.18e-11

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 68.37  E-value: 1.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 509 AAYFMNTLDL-DKWRIIAGLRYEgtEFSAKGTGIREGefeSISSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTvvrptf 587
Cdd:COG4774  358 GLYLQDTISLtDRWSLLAGLRYD--RFDTDYTDRTTG---ATTSSYDDSAFSPRAGLVYKPTPNLSLYASYSTS------ 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 588 eQLAPGFVIDGDEAefgNPDLKPLESMNYDLGI--EHYMGRAGAvSGYLFYKDIDNfIYNTDVAGTGQwadfdqalsYEN 665
Cdd:COG4774  427 -FNPGGGAPSLSNA---GQALDPEKSRQYEVGVkwDLLDGRLSL-TAALFRIEKTN-VRTTDPANPGV---------YVQ 491

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 666 GSSAKLYGVELSysqkLDWLPAP-WNgvlLGANATFSKS------DADIEGqgsRRSIDLPNHSdtvGNLMVGWENDVFN 738
Cdd:COG4774  492 TGEQRSRGVELE----ATGELTPgWS---VLAGYTYLDAeitksaNAANVG---NRLPNVPRHS---ASLWTTYDLPLPG 558

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 739 MRLA--ANYKSEYLAevagidDEAHDLYADEQLFLDFKAGYFITPNLQLTVEALNLTNESYFVYTGRSHYNAqyeeYGP- 815
Cdd:COG4774  559 LTLGggVRYVGSRYA------DAANTVKLPSYTRFDAGASYRLNKNLTLRLNVNNLTDKRYYASAYGSGYVT----PGAp 628

                        330
                 ....*....|
gi 518172354 816 -TYKLGLTLT 824
Cdd:COG4774  629 rTVLLSASYR 638
PRK13483 PRK13483
ligand-gated channel protein;
554-814 3.48e-11

ligand-gated channel protein;


Pssm-ID: 184080 [Multi-domain]  Cd Length: 660  Bit Score: 66.72  E-value: 3.48e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 554 RYD-------HWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGF-VIDGDEAEFGNPDLKPLESMNYDLGIEHYMG 625
Cdd:PRK13483 393 RLDhdenfggHVSPRVYGVWNLAPSWTVKGGVSTGFRAPSLRQTTPDWgQVSRGGNIYGNPDLKPETSLNKELGLYYDLG 472

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 626 RAGAVSGYLFYKDIDNFIynTDVA--------GTGQW-ADfdqALSYENGSSAKLYGVELSYSQKLDwlpapwNGVLLGA 696
Cdd:PRK13483 473 SGLTASLTVFYNEFKDKI--TRVAcpatqctdGPNQFgAD---PTTYVNIDEAVTQGVEASLSYPIT------STLSLSG 541

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 697 NATFSKSDADiEGQGSRRSID-LPNHsdtVGNLMVGWE-NDVFNMRLAANYKSEYLAEVAGidDEAHDLYADEQLFLDFK 774
Cdd:PRK13483 542 NYTYTDSEQK-SGAYKGSPLNqLPKH---LFQASLNWEpTDRLNSWARVNYRGEESQPTTG--PSSSSFIAPSYTFLDLG 615

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 518172354 775 AGYFITPNLQLTVEALNLTNEsyfvytgrshyNAQYEEYG 814
Cdd:PRK13483 616 ANYQLTDNLKLSAGIYNLFDK-----------EINYEEYG 644
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 62-823 3.84e-11

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 66.67  E-value: 3.84e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354   62 SVVHADGIGQLPDDNAAEALQRIPGLSVERDQGEGRF--VSVRGIAP--DLNSVTINGTLVPSPESgrravaLDVLPSEL 137
Cdd:TIGR01783   7 SVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFgnITIRGFGLevDIDNVYLDGVPLLSRGN------LAIVDPAM 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  138 VQSLSVVKtltpdmDANSL-------GGTIEVESLSAFDHdglfyslsTEGSYDENVGkTSPKFSGAISNRFSLGDGvDN 210
Cdd:TIGR01783  81 VERVEVLR------GPASLlyggsapGGVINIVTKRPQDE--------PKGSVTFGAG-TRSGYRTAFDLGGPLGAD-GT 144

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  211 FGVTAALSWQDRDfgsdnvetggkwDFEDGARleefeqrdyeitRERTGFGLNFDYQPDDlsSYYLRTLYSRFKDTETRN 290
Cdd:TIGR01783 145 FRGRLNGARQDGD------------SFYDGAG------------EETRLGATATDWQLDD--RTLLRLGAYYQKERDRGG 198

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  291 AAGVEFEDAQLAGELGS-----AEGWRELKSREETQTIQSyvfGGERMMGLWTLSGQVGYSEARE-RNPGGISSATFEGD 364
Cdd:TIGR01783 199 YGGLPASGGTSGRDLSSdrylgTSSNRNYDDREYLSYGLS---LEYQFNDVWTGKQNLRYSYFDTdSNQVQASGYSSDGG 275

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  365 FADVGFSSTTKPRLNVDpsfydpasfeldeveweetdardkeknIRLDLAREYDIQGYASQFKFGGklsrREKTNDVDIW 444
Cdd:TIGR01783 276 LFGRSLTVVNVKQDRVQ---------------------------IDAGLDGEFETGPIEHDLLLGV----SYGQRTTNRF 324

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  445 ayddfddltladfqagnvdyaLGRFGSGISAGALEGLIGGLDASAFYDEEESRIGDFDMSediNAAYFMNTLDLDKWRII 524
Cdd:TIGR01783 325 ---------------------NNTGYPSDNIYSLTATSSARTDIGDSPKDRALSSTTKAL---NGVALQRILLADKWTLT 380

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  525 AGLRYEGTEFSA-KGTGIREGEfesissdNRYDHWLPGLHVRYQLTDDTQLRAAwTNTVVRPtfEQLAPGFVIDGDEaef 603
Cdd:TIGR01783 381 LGGRYDSVDVKSnNGVAGSTGK-------RDDSQFTPSLGVAYKPTDDWSLYAS-YAESFKP--GGYYPKGAGNSGD--- 447

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  604 gnpDLKPLESMNYDLGIEHYMGRAGAVSGYLFYKDIDNFIYNtdvagtgqwaDFDQALSYENGSSAKLYGVELSysqkLD 683
Cdd:TIGR01783 448 ---ILEPEKGKNYELGVRYDLGDSLLATAALFRITKDNQLVQ----------DPVNGTFSVNAGKTRNRGVELE----AR 510

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  684 WLPAPwnGVLLGANATFSKSDADIEGQGSRRSIDLPNHSDTVGNLMVGWENDVFNMRLAANYKSEYLAEVAGIDDEAHDL 763
Cdd:TIGR01783 511 GYLTP--GLSLSAGYTYTDAEFTEDTNGDTQGNTVPFVPKHTASLWASYAPPVGDNGLTLGGGVQYTGKAYVDGGNTGKV 588

                         730       740       750       760       770       780
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 518172354  764 yaDEQLFLDFKAGYFITP--NLQLTVEALNLTNESYFVYTGRSHYNAQ-YEEYGPTYKLGLTL 823
Cdd:TIGR01783 589 --PSYTVVDLSVRYDLTKkkNLTLALNVNNLFDRDYYTSGYRWGPSAYiYPGAPRTVGLSVSY 649
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
62-289 2.16e-10

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 62.20  E-value: 2.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354  62 SVVHADGIGQLPDDNAAEALQRIPGLSVERDQGEGRF--VSVRGIAPDLNSVTINGTLVPSPESGrrAVALDVLPSELVQ 139
Cdd:COG4206   20 TVIDAEELERSGATSLADALRRVPGVQVSSSGGPGSAasISIRGLGSNQTLVLIDGVPLNDPSLG--GVDLSLIPPDDIE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 140 SLSVVKtltpdmDANS-------LGGTIEVESLSAFDHDGLFYSLSTeGSYdeNVGKTSPKFSGAiSNRFSLGDGV---- 208
Cdd:COG4206   98 RIEVLK------GAASalygsdaIGGVINITTKKGKKGFKGSVSASY-GSF--GTRRLSASLSGG-AGKFSYSLSAsyrr 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 209 -DNFGVTAALSWQDRDFGSDNVETGGKWDFEDGARLE--------EFEQRDYEITRERTGFGLNFDYQPDDLSSYYLRTL 279
Cdd:COG4206  168 sDGYRYNDPDLRNNDGYENTSLNARLGYKLGDNGSLSlsggysdsERGYPGAVGSDRNLRLSLSLEYKLSDGWSLLLLAY 247

                        250
                 ....*....|
gi 518172354 280 YSRFKDTETR 289
Cdd:COG4206  248 YYYDRDYEDG 257
PRK13484 PRK13484
IreA family TonB-dependent siderophore receptor;
529-796 2.48e-09

IreA family TonB-dependent siderophore receptor;


Pssm-ID: 139605 [Multi-domain]  Cd Length: 682  Bit Score: 60.79  E-value: 2.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 529 YEGTEFSAKGTGIREGEFESISSdnrydHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGF---VIDGDEAEFGN 605
Cdd:PRK13484 393 YAATDSLALTGGLRLDNHEIYGS-----YWNPRLYAVYNLTDNLTLKGGIAKAFRAPSIREVSPGFgtlTQGGASIMYGN 467

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 606 PDLKPLESMNYDLGIEHYMGRAGAVSGYLFYKDIDNFIYNTDVaGTGQWADFDQALSYENGSSAKLYGVELSYSqkldwL 685
Cdd:PRK13484 468 RDLKPETSVTEEIGIIYSNDSGFSASATLFNTDFKNKLTSYDI-GTKDPVTGLNTFIYDNVGEANIRGVELATQ-----I 541

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 686 PA--PWNgvlLGANATFSKS-----DADIEGQGSR-RSIDL-PNHSdtvGNLMVGWEND---VFNMRLAANYKSEYLAEV 753
Cdd:PRK13484 542 PVydKWH---VSANYTFTDSrrksdDESLNGKSLKgEPLERtPRHA---ANAKLEWDYTqdiTFYSSLNYTGKQIWAAQR 615

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 518172354 754 AGIDDEAhdlYADEQLFLDFKAGYFITPNLQLTVEALNLTNES 796
Cdd:PRK13484 616 NGAKVPR---VRNGFTSMDIGLNYQILPDTLINFAVLNVTDRK 655
PRK13486 PRK13486
TonB-dependent receptor;
557-797 8.16e-09

TonB-dependent receptor;


Pssm-ID: 139606 [Multi-domain]  Cd Length: 696  Bit Score: 59.27  E-value: 8.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 557 HWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGfvIDGDEAE-----FGNPDLKPLESMNYDLGI--EHYMGRAGA 629
Cdd:PRK13486 416 HFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLHKG--ISGVSGQgktnlLGNPDLKPEESVSYEAGVyyDNPAGLNAN 493

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 630 VSGylFYKDIDNFI--YNTDvagtgqwadfDQALSYENGSSAKLYGVELSYSqkldwLPAPWNGVLLGANATFSKSDA-D 706
Cdd:PRK13486 494 VTG--FMTDFSNKIvsYSIN----------DNTNSYVNSGKARLHGVEFAGT-----LPLWSEDVTLSLNYTWTRSEQrD 556

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 707 IEGQGSRRSIDlPNHsdtVGNLMVGWE-NDVFNMRLAANYK------SEYLAEVAGIDDEAHD---LYADEQLFLDFKAG 776
Cdd:PRK13486 557 GDNKGAPLSYT-PEH---MVNAKLNWQiTEEVASWLGARYRgktprfTQNYSSLSAVQKKVYDekgEYLKAWTVVDAGLS 632

                        250       260
                 ....*....|....*....|.
gi 518172354 777 YFITPNLQLTVEALNLTNESY 797
Cdd:PRK13486 633 WKMTDALTLNAAVNNLLNKDY 653
PRK13528 PRK13528
outer membrane receptor FepA; Provisional
 471-824 2.47e-06

outer membrane receptor FepA; Provisional


Pssm-ID: 237413 [Multi-domain]  Cd Length: 727  Bit Score: 51.30  E-value: 2.47e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 471 SGISAGALEGLIGGLDASAfydeeESRigDFDMSEDINAAYFMNTLDL-DKWRIIAGLRYE-GTEFSakgtgiregefes 548
Cdd:PRK13528 395 SSTSLTVKDGDIGGISGSA-----ADR--SSKNKSEISALYVEDNIEPvPGTNLIPGLRFDyHSEFG------------- 454

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 549 issdnryDHWLPGLHVRYQLTDDTQLRAAWTNTVVRPTFEQLAPGF------------VIDGDEAEFGNPDLKPLESMNY 616
Cdd:PRK13528 455 -------SNWSPSLNLSQELGDYFKVKAGIARAFKAPNLYQSSEGYllysrgngcpkdITSGGCYLVGNKNLDPEISVNK 527

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 617 DLGIEHYMG--RAGAVsgyLFYKDIDNFIyntdVAGT---GQWADFDQALSYENGSSAKLYGVELS-----YSQKLDWlp 686
Cdd:PRK13528 528 EIGLEFTVDdyHASVT---YFRNDYQNKI----VAGDdviGRTASGAYILQWQNGGKAVVEGLEGNllvplMKDRLNW-- 598

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 687 apwngvllGANATF---SKSDAdiegQGSRRSIdLPNHsdTVgNLMVGWE-NDVF----NMRLAANYKSEYLAEVAGIDD 758
Cdd:PRK13528 599 --------NTNATYmitSEQKD----TGNPLSV-IPKY--TI-NSTLDWQiTQALsanvNWTLYGKQKPRTHAESRSEET 662

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518172354 759 EAHDL-----YAdeqlFLDFKAGYFITPNLQLTVEALNLTNES-YFVYTGRSHYNaqyeEYGPTYKLGLTLT 824
Cdd:PRK13528 663 GGLSGkelgaYS----LVGVNVNYDINKNLRLNVGVSNLFDKQiYREGEGANTYN----EPGRAYYAGVTAS 726
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 509-822 4.65e-06

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 50.28  E-value: 4.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 509 AAYFMNTLDL-DKWRIIAGLRYegTEFSAKGTGIREGEfesiSSDNRYDHWLPGLHVRYQLTDDTQLRAAWTNTvvrptF 587
Cdd:COG4773  413 GLYAQDQISLtDRLSLLLGGRY--DWYETDSTNRLGGS----TTSYDDSAFTPRAGLVYDLTPGLSLYASYSES-----F 481

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 588 EqlaPGFVIDGDeaefGNPdLKPLESMNYDLGI--EHYMGRAGA-VSGYlfykDID-NFIYNTDVAGTGQWADFDQALSY 663
Cdd:COG4773  482 E---PQSGADNN----GNP-LDPETGKQYEAGVkgELFDGRLNAtLAVF----DITqKNVATTDPDNPNFYVQVGEVRSR 549

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 664 engssaklyGVELSysqkLDWLPAP-WNgvlLGANATFSKS---DADIEGQGSRrsidLPNHSDTVGNLMVGWE---NDV 736
Cdd:COG4773  550 ---------GVELE----LSGELTPgLN---LIAGYTYTDAkitKDADALEGKR----LTNVPRHTASLWTTYRfpsGAL 609

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 737 FNMRLAA--NYKSEYLAEVAGiddeahDLYADEQLFLDFKAGYFITPNLQLTVEALNLTNESYFVytgrSHYNAQYEEYG 814
Cdd:COG4773  610 KGLGLGGgvRYVGERYGDAAN------TFTLPSYTLVDAGARYDLGKNWTLQLNVNNLFDKKYYA----SSGSRGYVYYG 679

                        330
                 ....*....|
gi 518172354 815 P--TYKLGLT 822
Cdd:COG4773  680 AprNVRLSLS 689
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
603-675 2.46e-03

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 41.52  E-value: 2.46e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518172354 603 FGNPDLKPLESMNYDLGIEhymGRAGAV----SGYlfYKDIDNFIYNTDVAGTgqwadfdqalsYENGSSAKLYGVE 675
Cdd:PRK10641 425 YGNPNLKPEESKQWEGGFE---GLTGPVnwrlSGY--RNDIDNLIDYDDHTLK-----------YYNVGKATIKGVE 485
PRK13513 PRK13513
ligand-gated channel protein;
491-792 5.37e-03

ligand-gated channel protein;


Pssm-ID: 184104 [Multi-domain]  Cd Length: 659  Bit Score: 40.14  E-value: 5.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 491 YDEEESRigdfDMSEDINAAYFMNTLDLDKWRIIAGLRYEGTEFSAKGTGIREGEFEsissdNRYDHWLPGLHVRYQLTD 570
Cdd:PRK13513 338 YRYEELY----DKGNQLPSASDLNKLTRWSWALFAEDEWQMTNDFALTGGIRMDQDQ-----NYGTHWTPRLYGVWHLAD 408

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 571 DTQLRAAWTNTVVRPTFEQLAPGF-VIDG----DEAEFGNPDLKPLESMNYDLGIEHYMGRAGAVSGYLFYKDIDNFIYN 645
Cdd:PRK13513 409 QWTLKGGVSTGYRSPDLRQATDNWgQLTGggglPALILGNSDLKPEKSISQEIGILWDNQENLNASVTLFNTDFKDKITE 488

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 646 TDVAGTGqwaDFDQALSY-----------ENGSSAKLYGVELSYSQKLDwlpAPWNgvlLGANATFSKSD---ADIEGQG 711
Cdd:PRK13513 489 VRNCDTT---NTDGQCVFnginydfisdrINVDKANMRGVEATFNWDIN---QAWS---LATNYTFTQSEqksGAFAGQP 559

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 712 SRRsidLPNHsdtVGNLMVGWE-NDVFNMRLAANYK---SEYLAEVAGidDEAHDLYAdeqlFLDFKAGYFITPNLQLTV 787
Cdd:PRK13513 560 LNQ---MPKH---MANATLNWQtTEDFATWIRINYRgktSEYLNRTSM--GSGTPSYT----FVDLGASYQLTKELRLMG 627


                 ....*
gi 518172354 788 EALNL 792
Cdd:PRK13513 628 GVYNL 632
PRK13524 PRK13524
FepA family TonB-dependent siderophore receptor;
503-684 8.22e-03

FepA family TonB-dependent siderophore receptor;


Pssm-ID: 237410 [Multi-domain]  Cd Length: 744  Bit Score: 39.63  E-value: 8.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 503 MSEDINAAYFMNTLDL-DKWRIIAGLRYEgtefsakgtgiregeFESISSDNrydhWLPGLHVRYQLTDDTQLRAAWTNT 581
Cdd:PRK13524 428 SKAEIFSLFAEDNMELtDSTMLTPGLRFD---------------HHSIVGNN----WSPSLNLSQGLGDDFTLKMGIARA 488

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172354 582 VVRPTFEQLAPGFVI----DGDEAEF-------GNPDLKPLESMNYDLGIE--HYMGRAGAVsgyLFYKDIDNFIyntdV 648
Cdd:PRK13524 489 YKAPNLYQTNPNYILyskgQGCYASAgngcylqGNDDLKAETSVNKEIGLEfkRDGWLAGLT---WFRNDYRNKI----E 561

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 518172354 649 AGT---GQWAD-FDQALSYENGSSAKLYGVE----LSYSQKLDW 684
Cdd:PRK13524 562 AGYvpvGTNSVgKTDIYQWENVPKAVVEGLEgtlnVPVSETVNW 605
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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