NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|518172567|ref|WP_019342775|]
View 

type II secretion system protein N [Stutzerimonas stutzeri]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
T2SSC super family cl44344
Type II secretion system protein C; This is the greater N-terminal region of GspC-type ...
 21-148 3.69e-20

Type II secretion system protein C; This is the greater N-terminal region of GspC-type proteins. GspC proteins form part of the sophisticated transport mechanism of Gram-negative pathogens for injecting divers proteins into their hosts, a type-II secretion system - T2SS. The region is made up of a short N-terminal cytoplasmic domain that is followed by the single transmembrane helix, a Pro-rich linker, and the so-called homology region domain in the periplasm. This inner membrane GspC interacts with the outer membrane secretin GspD via periplasmic domains, an interaction which is critical for the effectiveness of type II secretion.


The actual alignment was detected with superfamily member pfam11356:

Pssm-ID: 457689  Cd Length: 142  Bit Score: 82.43  E-value: 3.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172567   21 VIVVLFGLYLAGQIMAWLQLSQtPATAMSDKSQPTGAAPDLERMER-------LFG------SPASSGQSYMPG-ESSSD 86
Cdd:pfam11356   2 LLLALLAWLAARLTWRLLAPAP-PATAAAASWAPSPASSSADRLDVagiaslnLFGkaapqaLAPKTAPVVVDApATRLN 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518172567   87 LTLLGSFVHADPARSTAIIQLSSQPPQLYRVDQEIEQGVRLYSVHPDRVEIKRGGRIESLQF 148
Cdd:pfam11356  81 LTLLGVVASSDPERGLAIIAERGKQEQTYRIGDEIPGGATLVAVYADRVIIRRNGRLETLML 142
 
Name Accession Description Interval E-value
T2SSC pfam11356
Type II secretion system protein C; This is the greater N-terminal region of GspC-type ...
 21-148 3.69e-20

Type II secretion system protein C; This is the greater N-terminal region of GspC-type proteins. GspC proteins form part of the sophisticated transport mechanism of Gram-negative pathogens for injecting divers proteins into their hosts, a type-II secretion system - T2SS. The region is made up of a short N-terminal cytoplasmic domain that is followed by the single transmembrane helix, a Pro-rich linker, and the so-called homology region domain in the periplasm. This inner membrane GspC interacts with the outer membrane secretin GspD via periplasmic domains, an interaction which is critical for the effectiveness of type II secretion.


Pssm-ID: 431837  Cd Length: 142  Bit Score: 82.43  E-value: 3.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172567   21 VIVVLFGLYLAGQIMAWLQLSQtPATAMSDKSQPTGAAPDLERMER-------LFG------SPASSGQSYMPG-ESSSD 86
Cdd:pfam11356   2 LLLALLAWLAARLTWRLLAPAP-PATAAAASWAPSPASSSADRLDVagiaslnLFGkaapqaLAPKTAPVVVDApATRLN 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518172567   87 LTLLGSFVHADPARSTAIIQLSSQPPQLYRVDQEIEQGVRLYSVHPDRVEIKRGGRIESLQF 148
Cdd:pfam11356  81 LTLLGVVASSDPERGLAIIAERGKQEQTYRIGDEIPGGATLVAVYADRVIIRRNGRLETLML 142
PulC COG3031
Type II secretory pathway, component PulC [Intracellular trafficking, secretion, and vesicular ...
 82-197 5.07e-18

Type II secretory pathway, component PulC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442267 [Multi-domain]  Cd Length: 220  Bit Score: 78.87  E-value: 5.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172567  82 ESSSDLTLLGSFVHADPARSTAIIQLSSQPPQLYRVDQEIEQGVRLYSVHPDRVEIKRGGRIESLQFPTvRSPTAAIDSL 161
Cdd:COG3031   21 ETRLNLTLLGVVASSDPERSFAIIAEGGGKQKSYRVGDEIPGGATLVAVYRDRVILSNNGRLETLMLDG-EDYAAPAAAA 99

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 518172567 162 PDYSSEPTemEALDPQAEMLQQQMEALRQQMEGAPS 197
Cdd:COG3031  100 AAPASSPA--ASSAAASAGGQEELEVSRDELLANPN 133
 
Name Accession Description Interval E-value
T2SSC pfam11356
Type II secretion system protein C; This is the greater N-terminal region of GspC-type ...
 21-148 3.69e-20

Type II secretion system protein C; This is the greater N-terminal region of GspC-type proteins. GspC proteins form part of the sophisticated transport mechanism of Gram-negative pathogens for injecting divers proteins into their hosts, a type-II secretion system - T2SS. The region is made up of a short N-terminal cytoplasmic domain that is followed by the single transmembrane helix, a Pro-rich linker, and the so-called homology region domain in the periplasm. This inner membrane GspC interacts with the outer membrane secretin GspD via periplasmic domains, an interaction which is critical for the effectiveness of type II secretion.


Pssm-ID: 431837  Cd Length: 142  Bit Score: 82.43  E-value: 3.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172567   21 VIVVLFGLYLAGQIMAWLQLSQtPATAMSDKSQPTGAAPDLERMER-------LFG------SPASSGQSYMPG-ESSSD 86
Cdd:pfam11356   2 LLLALLAWLAARLTWRLLAPAP-PATAAAASWAPSPASSSADRLDVagiaslnLFGkaapqaLAPKTAPVVVDApATRLN 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518172567   87 LTLLGSFVHADPARSTAIIQLSSQPPQLYRVDQEIEQGVRLYSVHPDRVEIKRGGRIESLQF 148
Cdd:pfam11356  81 LTLLGVVASSDPERGLAIIAERGKQEQTYRIGDEIPGGATLVAVYADRVIIRRNGRLETLML 142
PulC COG3031
Type II secretory pathway, component PulC [Intracellular trafficking, secretion, and vesicular ...
 82-197 5.07e-18

Type II secretory pathway, component PulC [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442267 [Multi-domain]  Cd Length: 220  Bit Score: 78.87  E-value: 5.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518172567  82 ESSSDLTLLGSFVHADPARSTAIIQLSSQPPQLYRVDQEIEQGVRLYSVHPDRVEIKRGGRIESLQFPTvRSPTAAIDSL 161
Cdd:COG3031   21 ETRLNLTLLGVVASSDPERSFAIIAEGGGKQKSYRVGDEIPGGATLVAVYRDRVILSNNGRLETLMLDG-EDYAAPAAAA 99

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 518172567 162 PDYSSEPTemEALDPQAEMLQQQMEALRQQMEGAPS 197
Cdd:COG3031  100 AAPASSPA--ASSAAASAGGQEELEVSRDELLANPN 133
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH