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Conserved domains on  [gi|518267576|ref|WP_019437784|]
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MULTISPECIES: TerD family protein [Pseudomonas]

Protein Classification

TerD family protein( domain architecture ID 10161385)

TerD family protein similar to Streptomyces avermitilis protein SAV2460 and Streptomyces coelicolor protein SCO6318

CATH:  2.60.60.30
PubMed:  11016400|10203839
SCOP:  4006781

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TerD_like cd06974
Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; ...
 25-170 1.26e-34

Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.


:

Pssm-ID: 132992  Cd Length: 162  Bit Score: 125.87  E-value: 1.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576  25 SAGANLDVNLTAFLVTDTGKVIDDSGMVFFNAPEHASGAAAFSPPINQAGTVS-HSISFDLSRLPPTISKIAITLTQDGs 103
Cdd:cd06974   14 STGGGIDLDLSAFLLDADGKVRGDADVVFYNQLSSPDGAVRLSGDNRTGGDGDdETITVDLDRLPPDIRRIVFTVTIYE- 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576 104 GGGFAEVPNLTARVIAG---EQILDLAPGAFDRETGIIVLELYIRNGQAKARSVWQGFASGLAGLCGMYG 170
Cdd:cd06974   93 GQPFGQVENAFVRLVDAggnTELARYDLTEDSGETALILAELYRRNGEWKFRAVGQGFNGGLAALATHYG 162
 
Name Accession Description Interval E-value
TerD_like cd06974
Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; ...
 25-170 1.26e-34

Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.


Pssm-ID: 132992  Cd Length: 162  Bit Score: 125.87  E-value: 1.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576  25 SAGANLDVNLTAFLVTDTGKVIDDSGMVFFNAPEHASGAAAFSPPINQAGTVS-HSISFDLSRLPPTISKIAITLTQDGs 103
Cdd:cd06974   14 STGGGIDLDLSAFLLDADGKVRGDADVVFYNQLSSPDGAVRLSGDNRTGGDGDdETITVDLDRLPPDIRRIVFTVTIYE- 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576 104 GGGFAEVPNLTARVIAG---EQILDLAPGAFDRETGIIVLELYIRNGQAKARSVWQGFASGLAGLCGMYG 170
Cdd:cd06974   93 GQPFGQVENAFVRLVDAggnTELARYDLTEDSGETALILAELYRRNGEWKFRAVGQGFNGGLAALATHYG 162
TerD pfam02342
TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, ...
 1-169 4.62e-28

TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.


Pssm-ID: 426730  Cd Length: 187  Bit Score: 109.13  E-value: 4.62e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576    1 MSQSLKPGENTTINQ--PK-GQVLV------AHSAGANLDVNLTAFLVTDTGKVIDDSGMVFFNAPEHASGAAAFSPpIN 71
Cdd:pfam02342   1 MAISLQKGQNISLTKeaPGlTKVMVglgwdvNKTGGADFDLDASAFLLGANGKVRSDEDFVFYNNLKSPDGSVRHLG-DN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576   72 QAGTVS---HSISFDLSRLPPTISKIAITLT---QDGSGGGFAEVPNLTARVI---AGEQIL--DLAPgAFDRETGIIVL 140
Cdd:pfam02342  80 LTGEGDgddEQIEVDLSKVPADVEKIVFVVTiydAEARRQNFGQVRNAYIRVVdaaTGEELAryDLSE-DFSGETALIFG 158

                         170       180
                  ....*....|....*....|....*....
gi 518267576  141 ELYIRNGQAKARSVWQGFASGLAGLCGMY 169
Cdd:pfam02342 159 ELYRHGGEWKFRAVGQGYAGGLAGLATDY 187
TerZ COG2310
Stress response protein SCP2 [Signal transduction mechanisms];
1-169 7.91e-28

Stress response protein SCP2 [Signal transduction mechanisms];


Pssm-ID: 441884  Cd Length: 187  Bit Score: 108.72  E-value: 7.91e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576   1 MSQSLKPGENTTI---NQPKGQVLV------AHSAGANLDVNLTAFLVTDTGKVIDDSGMVFFNAPEHASGAAAFSPPiN 71
Cdd:COG2310    1 MAISLQKGQNISLtkeAPGLTKVRVglgwdpAKTDGGDFDLDASAFLLDANGKVRSDEDFVFYNNLKSPDGSVRHTGD-N 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576  72 QAGTVSH---SISFDLSRLPPTISKIAITLT---QDGSGGGFAEVPNLTARVI---AGEQIL--DLAPGaFDRETGIIVL 140
Cdd:COG2310   80 RTGEGDGddeQITVDLSKVPADVEKIVFVVTiydAEARGQNFGQVSNAFIRVVdaaTGEELAryDLSED-FSGETAMVFG 158

                        170       180
                 ....*....|....*....|....*....
gi 518267576 141 ELYIRNGQAKARSVWQGFASGLAGLCGMY 169
Cdd:COG2310  159 ELYRHGGEWKFRAVGQGYNGGLAGLATDY 187
 
Name Accession Description Interval E-value
TerD_like cd06974
Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; ...
 25-170 1.26e-34

Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Tellurium resistance terD like proteins. This family is composed of uncharacterized proteins involved in stress response, such as the tellurium resistance proteins, chemical-damaging agent resistance proteins, and general stress proteins from a variety of organisms. The tellurium resistance proteins are homologous terA,-D,-E,-F,-Z,-X gene products, which confer tellurium resistance mediated by plasmids. Currently, the biochemical mechanism of tellurium resistance remains unknown. The family also contains several ter gene homologues, YceC, YceD, YceE, for which there is no clear evidence for any involvement in the tellurium resistance. A putative cAMP-binding protin CABP1 shows a significant similarity to the terD protein and is also included in this family.


Pssm-ID: 132992  Cd Length: 162  Bit Score: 125.87  E-value: 1.26e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576  25 SAGANLDVNLTAFLVTDTGKVIDDSGMVFFNAPEHASGAAAFSPPINQAGTVS-HSISFDLSRLPPTISKIAITLTQDGs 103
Cdd:cd06974   14 STGGGIDLDLSAFLLDADGKVRGDADVVFYNQLSSPDGAVRLSGDNRTGGDGDdETITVDLDRLPPDIRRIVFTVTIYE- 92

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576 104 GGGFAEVPNLTARVIAG---EQILDLAPGAFDRETGIIVLELYIRNGQAKARSVWQGFASGLAGLCGMYG 170
Cdd:cd06974   93 GQPFGQVENAFVRLVDAggnTELARYDLTEDSGETALILAELYRRNGEWKFRAVGQGFNGGLAALATHYG 162
TerD pfam02342
TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, ...
 1-169 4.62e-28

TerD domain; The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.


Pssm-ID: 426730  Cd Length: 187  Bit Score: 109.13  E-value: 4.62e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576    1 MSQSLKPGENTTINQ--PK-GQVLV------AHSAGANLDVNLTAFLVTDTGKVIDDSGMVFFNAPEHASGAAAFSPpIN 71
Cdd:pfam02342   1 MAISLQKGQNISLTKeaPGlTKVMVglgwdvNKTGGADFDLDASAFLLGANGKVRSDEDFVFYNNLKSPDGSVRHLG-DN 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576   72 QAGTVS---HSISFDLSRLPPTISKIAITLT---QDGSGGGFAEVPNLTARVI---AGEQIL--DLAPgAFDRETGIIVL 140
Cdd:pfam02342  80 LTGEGDgddEQIEVDLSKVPADVEKIVFVVTiydAEARRQNFGQVRNAYIRVVdaaTGEELAryDLSE-DFSGETALIFG 158

                         170       180
                  ....*....|....*....|....*....
gi 518267576  141 ELYIRNGQAKARSVWQGFASGLAGLCGMY 169
Cdd:pfam02342 159 ELYRHGGEWKFRAVGQGYAGGLAGLATDY 187
TerZ COG2310
Stress response protein SCP2 [Signal transduction mechanisms];
1-169 7.91e-28

Stress response protein SCP2 [Signal transduction mechanisms];


Pssm-ID: 441884  Cd Length: 187  Bit Score: 108.72  E-value: 7.91e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576   1 MSQSLKPGENTTI---NQPKGQVLV------AHSAGANLDVNLTAFLVTDTGKVIDDSGMVFFNAPEHASGAAAFSPPiN 71
Cdd:COG2310    1 MAISLQKGQNISLtkeAPGLTKVRVglgwdpAKTDGGDFDLDASAFLLDANGKVRSDEDFVFYNNLKSPDGSVRHTGD-N 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518267576  72 QAGTVSH---SISFDLSRLPPTISKIAITLT---QDGSGGGFAEVPNLTARVI---AGEQIL--DLAPGaFDRETGIIVL 140
Cdd:COG2310   80 RTGEGDGddeQITVDLSKVPADVEKIVFVVTiydAEARGQNFGQVSNAFIRVVdaaTGEELAryDLSED-FSGETAMVFG 158

                        170       180
                 ....*....|....*....|....*....
gi 518267576 141 ELYIRNGQAKARSVWQGFASGLAGLCGMY 169
Cdd:COG2310  159 ELYRHGGEWKFRAVGQGYNGGLAGLATDY 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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