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Concise Results
Standard Results
Full Results
malate synthase A [Moritella marina]
Protein Classification
malate synthase ( domain architecture ID 10006197 )
malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA, in the glyoxylate cycle
List of domain hits
Name
Accession
Description
Interval
E-value
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
6-538
0e+00
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 996.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 6 QSHETGSLIFH G EINQEQQQ IL N P A A V A L L T EL VEK FAP QVD ELL NQ R VKK QAR M DAGELPDFLPETA H IREGDWK IQG I 85
Cdd:COG2225 1 TQTTPSGVEIT G PLGPRYEE IL T P E A L A F L A EL HRR FAP RRQ ELL AA R AER QAR I DAGELPDFLPETA S IREGDWK VAP I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 86 P AK LQDRRVEITGPVDRKMVINALN ARV KVFMADFED SFA PTW AG V LD GQ V NLRDAV N GTI EY T N P a N GK H Y S L DED PAT 165
Cdd:COG2225 81 P PD LQDRRVEITGPVDRKMVINALN SGA KVFMADFED ANS PTW DN V IE GQ I NLRDAV R GTI SF T S P - E GK E Y R L NDK PAT 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 166 LI C R V RG L HLPEKH ITFN G KIVP G C L V DF A L F F SN N YEE LLA K G A GPYFY V PKL Q SH H E SKW W SE VF SY A E D KVNLA RGT 245
Cdd:COG2225 160 LI V R P RG W HLPEKH VLVD G EPIS G S L F DF G L Y F FH N AKA LLA R G S GPYFY L PKL E SH L E ARL W ND VF VF A Q D ELGIP RGT 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 246 IKAT L LIETIPA V FEM E EILY SMKE H IVA LNCGRWDYIFSYIKT L R K H A D R VLPDR HS VTM DKT F LS AYS R LL IR TCH K R 325
Cdd:COG2225 240 IKAT V LIETIPA A FEM D EILY ELRD H SAG LNCGRWDYIFSYIKT F R N H P D F VLPDR AQ VTM TVP F MR AYS E LL VK TCH R R 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 326 GA L A M GGMAAFIP A K - TA E E N DKV L T KV T ADK TL EA QN GHDGTWVAHPGL ADT AM G V MNEYI G EG n A NQ IQVS R a D D AP V 404
Cdd:COG2225 320 GA H A I GGMAAFIP I K n DP E A N EAA L A KV R ADK ER EA ND GHDGTWVAHPGL VPV AM E V FDAVL G DR - P NQ LDRL R - E D VS V 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 405 TAA E LL QPCD G ER TEAG M R L NI RI G VR Y M EAW IS GNG C VPIY G LMEDAATAEISR ASI WQWI Q HG K TL SN G KV VT K EL FS 484
Cdd:COG2225 398 TAA D LL DVPE G TI TEAG L R N NI SV G IQ Y L EAW LR GNG A VPIY N LMEDAATAEISR SQV WQWI H HG A TL DD G RK VT A EL VR 477
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 518270166 485 QLL Q EEL VVI R d E E I G V E AY E NS RF A EA SK LFEEL TI SD HLAE FLTLP G Y DF LD 538
Cdd:COG2225 478 QLL A EEL AKL R - A E V G E E RF E AG RF D EA AE LFEEL VL SD EFPD FLTLP A Y ER LD 530
Name
Accession
Description
Interval
E-value
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
6-538
0e+00
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 996.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 6 QSHETGSLIFH G EINQEQQQ IL N P A A V A L L T EL VEK FAP QVD ELL NQ R VKK QAR M DAGELPDFLPETA H IREGDWK IQG I 85
Cdd:COG2225 1 TQTTPSGVEIT G PLGPRYEE IL T P E A L A F L A EL HRR FAP RRQ ELL AA R AER QAR I DAGELPDFLPETA S IREGDWK VAP I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 86 P AK LQDRRVEITGPVDRKMVINALN ARV KVFMADFED SFA PTW AG V LD GQ V NLRDAV N GTI EY T N P a N GK H Y S L DED PAT 165
Cdd:COG2225 81 P PD LQDRRVEITGPVDRKMVINALN SGA KVFMADFED ANS PTW DN V IE GQ I NLRDAV R GTI SF T S P - E GK E Y R L NDK PAT 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 166 LI C R V RG L HLPEKH ITFN G KIVP G C L V DF A L F F SN N YEE LLA K G A GPYFY V PKL Q SH H E SKW W SE VF SY A E D KVNLA RGT 245
Cdd:COG2225 160 LI V R P RG W HLPEKH VLVD G EPIS G S L F DF G L Y F FH N AKA LLA R G S GPYFY L PKL E SH L E ARL W ND VF VF A Q D ELGIP RGT 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 246 IKAT L LIETIPA V FEM E EILY SMKE H IVA LNCGRWDYIFSYIKT L R K H A D R VLPDR HS VTM DKT F LS AYS R LL IR TCH K R 325
Cdd:COG2225 240 IKAT V LIETIPA A FEM D EILY ELRD H SAG LNCGRWDYIFSYIKT F R N H P D F VLPDR AQ VTM TVP F MR AYS E LL VK TCH R R 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 326 GA L A M GGMAAFIP A K - TA E E N DKV L T KV T ADK TL EA QN GHDGTWVAHPGL ADT AM G V MNEYI G EG n A NQ IQVS R a D D AP V 404
Cdd:COG2225 320 GA H A I GGMAAFIP I K n DP E A N EAA L A KV R ADK ER EA ND GHDGTWVAHPGL VPV AM E V FDAVL G DR - P NQ LDRL R - E D VS V 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 405 TAA E LL QPCD G ER TEAG M R L NI RI G VR Y M EAW IS GNG C VPIY G LMEDAATAEISR ASI WQWI Q HG K TL SN G KV VT K EL FS 484
Cdd:COG2225 398 TAA D LL DVPE G TI TEAG L R N NI SV G IQ Y L EAW LR GNG A VPIY N LMEDAATAEISR SQV WQWI H HG A TL DD G RK VT A EL VR 477
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 518270166 485 QLL Q EEL VVI R d E E I G V E AY E NS RF A EA SK LFEEL TI SD HLAE FLTLP G Y DF LD 538
Cdd:COG2225 478 QLL A EEL AKL R - A E V G E E RF E AG RF D EA AE LFEEL VL SD EFPD FLTLP A Y ER LD 530
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
26-538
0e+00
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 838.45
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 26 IL N P A A VAL L T EL VEK F A P QVD ELL NQ R VKK QAR M DAGELPDFLPETAHIR E GDWK IQGI P AK LQDRRVEITGPVDRKMV 105
Cdd:cd00727 1 IL T P E A LDF L A EL HRR F N P RRK ELL AA R KER QAR L DAGELPDFLPETAHIR D GDWK VAPV P PD LQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 106 INALN ARV KVFMADFED SF APTW AGVLD GQ V NLRDAV N GTI EY T N P a N GK H Y S L DED PATLI C R V RG L HLPEKH ITFN G K 185
Cdd:cd00727 81 INALN SGA KVFMADFED AN APTW ENQVE GQ I NLRDAV R GTI SF T S P - E GK E Y K L NDT PATLI V R P RG W HLPEKH VLVD G E 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 186 I V P G C L V DF A L F F SN N YEE LLA K G A GPYFY V PK LQ SH H E SKW W SE VF SY A E D KVN L A RGTIKAT L LIET I PA V FEM E EIL 265
Cdd:cd00727 160 P V S G S L F DF G L Y F FH N AKA LLA R G S GPYFY L PK ME SH L E ARL W ND VF VF A Q D YLG L P RGTIKAT V LIET L PA A FEM D EIL 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 266 Y SMKE H IVA LNCGRWDYIFS Y IK TL R K H A D R VLPDR HS VTM DKT F LS AYS R LLI R TCH K RGA L AMGGMAA F IP A K - TAEE 344
Cdd:cd00727 240 Y ELRD H SAG LNCGRWDYIFS F IK KF R N H P D F VLPDR AQ VTM TVP F MR AYS E LLI K TCH R RGA H AMGGMAA Q IP I K d DPAA 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 345 N DKV L T KV T ADK TL EA QN GHDGTWVAHPGL ADT AM G V MNEYIGE gn A NQ IQ V S R a D D AP VTAA E LL Q - P CD G ER TE A G M R 423
Cdd:cd00727 320 N EAA L A KV R ADK LR EA TA GHDGTWVAHPGL VPV AM E V FDKHMPG -- P NQ LD V L R - E D VK VTAA D LL L v P VE G GI TE E G L R 396
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 424 L NI RI G VR Y ME AW IS GNGCVPIY G LMEDAATAEISRA SI WQWI Q HG KT - L SN G KV VT K EL FSQ LL Q EEL VVIR d E E I G VE 502
Cdd:cd00727 397 Q NI SV G LQ Y LA AW LR GNGCVPIY N LMEDAATAEISRA QL WQWI R HG VR l L DD G RP VT A EL VEK LL A EEL AKLK - A E V G QA 475
490 500 510
....*....|....*....|....*....|....*.
gi 518270166 503 AYENS R F AEA SK LFEEL TISDHLA EFLTLP G YD F L D 538
Cdd:cd00727 476 GFATG R L AEA AE LFEEL VTAEEFP EFLTLP A YD D L V 511
malate_syn_A
TIGR01344 malate synthase A; This model represents plant malate synthase and one of two bacterial forms, ...
26-537
0e+00
malate synthase A; This model represents plant malate synthase and one of two bacterial forms, designated malate synthase A. The distantly related malate synthase G is described by a separate model. This enzyme and isocitrate lyase are the two characteristic enzymes of the glyoxylate shunt. The shunt enables the cell to use acetyl-CoA to generate increased levels of TCA cycle intermediates for biosynthetic pathways such as gluconeogenesis. [Energy metabolism, TCA cycle]
Pssm-ID: 188132
Cd Length: 511
Bit Score: 814.81
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 26 I L N P A A VAL L TE L VEK F A P QV D E LL NQ R VKK QA RM D A G E LPDFLPETA H IRE G DW K I QG IP AK LQDRRVEITGPVDRKMV 105
Cdd:TIGR01344 1 V L T P E A LEF L AL L HRR F N P RR D Q LL AR R SNR QA KI D S G Y LPDFLPETA Q IRE D DW T I AP IP PD LQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 106 INALNA RV KVFMADFEDS FA PTW AG V LD GQ V NLRDA VN G T I EY T N P AN GK H Y S L DEDP A T LI C R V RG L HLPE K H I T FN G K 185
Cdd:TIGR01344 81 INALNA GA KVFMADFEDS SS PTW EN V IY GQ I NLRDA IR G Q I DF T D P TS GK E Y A L NARL A V LI V R P RG W HLPE R H L T ID G E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 186 IV PG C L V DF A L F F SN N YEE LL A KG A GPYFY V PKL Q SH H E SKW W SE VF SY A E D KVN L A RGTIKAT L LIET I PA V FEM E EIL 265
Cdd:TIGR01344 161 AI PG S L F DF G L Y F FH N ARA LL K KG K GPYFY L PKL E SH Q E ARL W ND VF HF A Q D FLG L P RGTIKAT V LIET L PA A FEM D EIL 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 266 Y SMK EHI VA LNCGRWDYIFS Y IKTLR KHADR VLPDR HS VTM D K T FL S AYS R LLI R TCH K RGA L AMGGMAAFIP A K TAEE - 344
Cdd:TIGR01344 241 Y ELR EHI SG LNCGRWDYIFS F IKTLR NLPEF VLPDR DA VTM T K P FL N AYS K LLI Q TCH R RGA H AMGGMAAFIP I K GDPA a 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 345 N DKVLT KV T ADK TL EA Q NGHDGTWVAHP G L ADT AM G V M N EYI G E gn A NQ IQVS R AD D APV TAAELL QPC DG E RTEAG M R L 424
Cdd:TIGR01344 321 N EAAFN KV R ADK IR EA K NGHDGTWVAHP D L VPV AM E V F N NVM G T -- P NQ LDRV R DE D VSI TAAELL AVP DG S RTEAG L R H 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 425 NIR I G VR Y M EAW IS G N GCVPIY G LMEDAATAEISRA SI WQWI Q HG KT L SN G K VVT K ELF SQ LL QE E LVVI R d E E I G V E AY 504
Cdd:TIGR01344 399 NIR V G LQ Y I EAW LR G S GCVPIY H LMEDAATAEISRA QL WQWI K HG VV L DD G R VVT P ELF RD LL NQ E MGKL R - S E S G L E EF 477
490 500 510
....*....|....*....|....*....|...
gi 518270166 505 ENS RF A EA S KLF EE L TI S DH L AE FLT L P G YD F L 537
Cdd:TIGR01344 478 AAG RF E EA A KLF LR L VT S KE L ED FLT I P A YD E L 510
Malate_synthase
pfam01274 Malate synthase;
15-537
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 739.98
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 15 F H G EINQEQQQ IL NPA A VALLT EL VEK F A P QVD ELL NQ R VKK QAR M DAG E LPDFLPET AH IR - EG DWK IQGIPAK LQDRR 93
Cdd:pfam01274 3 F V G PYVLPGTG IL TKE A LSFVA EL HRD F T P RRR ELL AR R DER QAR I DAG H LPDFLPET GY IR p DP DWK TATLHPE LQDRR 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 94 VEITGP V DRKM V INALN ARVKVF MADFEDS F APTW AGVLD GQ V NL R DAV N G T I EYTNPAN GK H Y S L --- DEDP ATL IC R V 170
Cdd:pfam01274 83 VEITGP A DRKM I INALN SGAITT MADFEDS V APTW NNLIQ GQ L NL Y DAV R G R I DFRDLNA GK S Y K L ndg LHGR ATL FV R P 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 171 RG L HLPEKHI TFN G KIV PG CLV DF A L F F SN N YE EL LAK G A GPYFY V PK LQS H H E SKW W SE VF SY AED KVNLA RGTI K AT L 250
Cdd:pfam01274 163 RG W HLPEKHI LVD G EPI PG GIF DF G L Y F FH N AK EL NSR G G GPYFY L PK MEH H Q E AAL W ND VF NR AED YLGIP RGTI R AT V 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 251 LIET I PA V F E M E EI L Y SMKE H IVA LNCGRWDYIFSYIKTLR KHA D R VLPDR HS VTM DKT F LS AY SR LLI R TCHKRG AL AM 330
Cdd:pfam01274 243 LIET L PA S F Q M D EI I Y ELRD H SAG LNCGRWDYIFSYIKTLR NAP D M VLPDR KA VTM TAP F MR AY EK LLI K TCHKRG VH AM 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 331 GGMAA F IP A K TAE E - N DKVLT KV T ADK TL E AQN GHDGTWVAHPGLA DT A MG V MNEYI ge GNA NQI QVS R AD D a PV TA AE L 409
Cdd:pfam01274 323 GGMAA Q IP I K DDM E a N TAAME KV R ADK LR E VRA GHDGTWVAHPGLA PL A AE V FHQVM -- VRP NQI ELA R EE D - SI TA DD L 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 410 L QPC DGE R TE A G M R L NI RI G VR Y M EAW IS G N GCVPI YG LMEDAATAEISR ASI WQW IQ HG K TL SN G KV VT K EL FSQ L LQ E 489
Cdd:pfam01274 400 L TIP DGE E TE E G L R N NI QV G LQ Y V EAW LR G S GCVPI IH LMEDAATAEISR QQL WQW LR HG V TL DE G VR VT L EL MAK L VD E 479
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 518270166 490 E L vvird EEIGV E AYENSRFAE A SK LF EELTISDHLAE FLTL PG YD F L 537
Cdd:pfam01274 480 E N ----- ARLAK E RFGDGAYRD A AR LF LQQATAEEYDD FLTL LA YD D L 522
PLN02626
PLN02626 malate synthase
16-535
0e+00
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 715.78
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 16 H G EINQ E QQQ IL NPA A VALLTE L VEK F A P QVDE LL NQ R VKK Q A R M DAG E LP D F L P E T AHI REGDW KIQGI P AKLQ DRRVE 95
Cdd:PLN02626 15 R G PYDA E FAK IL TRD A LQFVAD L QRE F R P RRKY LL EC R REA Q R R Y DAG A LP G F D P A T RAV REGDW RCAPV P PAVA DRRVE 94
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 96 ITGPV D RKMVINALN ARV KVFMADFEDS FA PTW AGVLD GQVNLRDAV N GTI EY T NP A N GK H Y S L DEDP A T L IC R V RG L HL 175
Cdd:PLN02626 95 ITGPV E RKMVINALN SGA KVFMADFEDS LS PTW ENLMR GQVNLRDAV R GTI TF T DK A R GK V Y K L NDKT A K L FV R P RG W HL 174
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 176 PE K HI TFN G KIVP G C L V DF A L F F SN NY EELL AK -- G A GP Y FY V PK LQSHH E SKW W SE VF SY AE DKVNLA RG T I K AT L LIE 253
Cdd:PLN02626 175 PE A HI LVD G EPAT G S L F DF G L Y F FH NY AAFR AK qg G F GP F FY L PK MEHSR E ARL W ND VF EA AE KMAGIP RG S I R AT V LIE 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 254 T I PAVF E MEEILY SMKE H IVA LNCGRWDYIFS YI KT L R K H A DR V LPDR HS V T M DKT F LSA Y SR LLI R TCHKRG AL AMGGM 333
Cdd:PLN02626 255 T L PAVF Q MEEILY ELRD H SAG LNCGRWDYIFS FV KT F R A H P DR L LPDR VQ V G M TQH F MKS Y VD LLI K TCHKRG VH AMGGM 334
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 334 AA F IP A K - TAEE N DKV L TK V TA DK TL E AQN GHDGTW V AHPGL ADT AM G V MNEYI ge GNA N QI Q - VS R A DD AP VT A A E LLQ 411
Cdd:PLN02626 335 AA Q IP I K d DPAA N EAA L AL V RK DK LR E VRA GHDGTW A AHPGL IPL AM E V FDGHM -- PTP N NQ Q l HK R R DD VN VT E A D LLQ 412
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 412 PCD G E RT EA G M RLN I R I G VR Y ME AW IS G N G C VP I Y G LMEDAATAEISR ASI WQWI QH G KT L SNGK V --- VT K ELF SQLLQ 488
Cdd:PLN02626 413 VPR G V RT LE G L RLN T R V G IQ Y LA AW LT G T G S VP L Y N LMEDAATAEISR VQN WQWI KY G AE L DGDG V gvr VT A ELF GRVVE 492
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 518270166 489 EE LVV I r DE E I G V E AYENSRFA EA S KLF EELTISDH L AE FLTL PG Y D 535
Cdd:PLN02626 493 EE MAR I - ER E V G K E RFKKGKYK EA A KLF ARQCTAPE L DD FLTL DA Y N 538
Name
Accession
Description
Interval
E-value
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
6-538
0e+00
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 996.92
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 6 QSHETGSLIFH G EINQEQQQ IL N P A A V A L L T EL VEK FAP QVD ELL NQ R VKK QAR M DAGELPDFLPETA H IREGDWK IQG I 85
Cdd:COG2225 1 TQTTPSGVEIT G PLGPRYEE IL T P E A L A F L A EL HRR FAP RRQ ELL AA R AER QAR I DAGELPDFLPETA S IREGDWK VAP I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 86 P AK LQDRRVEITGPVDRKMVINALN ARV KVFMADFED SFA PTW AG V LD GQ V NLRDAV N GTI EY T N P a N GK H Y S L DED PAT 165
Cdd:COG2225 81 P PD LQDRRVEITGPVDRKMVINALN SGA KVFMADFED ANS PTW DN V IE GQ I NLRDAV R GTI SF T S P - E GK E Y R L NDK PAT 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 166 LI C R V RG L HLPEKH ITFN G KIVP G C L V DF A L F F SN N YEE LLA K G A GPYFY V PKL Q SH H E SKW W SE VF SY A E D KVNLA RGT 245
Cdd:COG2225 160 LI V R P RG W HLPEKH VLVD G EPIS G S L F DF G L Y F FH N AKA LLA R G S GPYFY L PKL E SH L E ARL W ND VF VF A Q D ELGIP RGT 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 246 IKAT L LIETIPA V FEM E EILY SMKE H IVA LNCGRWDYIFSYIKT L R K H A D R VLPDR HS VTM DKT F LS AYS R LL IR TCH K R 325
Cdd:COG2225 240 IKAT V LIETIPA A FEM D EILY ELRD H SAG LNCGRWDYIFSYIKT F R N H P D F VLPDR AQ VTM TVP F MR AYS E LL VK TCH R R 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 326 GA L A M GGMAAFIP A K - TA E E N DKV L T KV T ADK TL EA QN GHDGTWVAHPGL ADT AM G V MNEYI G EG n A NQ IQVS R a D D AP V 404
Cdd:COG2225 320 GA H A I GGMAAFIP I K n DP E A N EAA L A KV R ADK ER EA ND GHDGTWVAHPGL VPV AM E V FDAVL G DR - P NQ LDRL R - E D VS V 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 405 TAA E LL QPCD G ER TEAG M R L NI RI G VR Y M EAW IS GNG C VPIY G LMEDAATAEISR ASI WQWI Q HG K TL SN G KV VT K EL FS 484
Cdd:COG2225 398 TAA D LL DVPE G TI TEAG L R N NI SV G IQ Y L EAW LR GNG A VPIY N LMEDAATAEISR SQV WQWI H HG A TL DD G RK VT A EL VR 477
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....
gi 518270166 485 QLL Q EEL VVI R d E E I G V E AY E NS RF A EA SK LFEEL TI SD HLAE FLTLP G Y DF LD 538
Cdd:COG2225 478 QLL A EEL AKL R - A E V G E E RF E AG RF D EA AE LFEEL VL SD EFPD FLTLP A Y ER LD 530
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
26-538
0e+00
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 838.45
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 26 IL N P A A VAL L T EL VEK F A P QVD ELL NQ R VKK QAR M DAGELPDFLPETAHIR E GDWK IQGI P AK LQDRRVEITGPVDRKMV 105
Cdd:cd00727 1 IL T P E A LDF L A EL HRR F N P RRK ELL AA R KER QAR L DAGELPDFLPETAHIR D GDWK VAPV P PD LQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 106 INALN ARV KVFMADFED SF APTW AGVLD GQ V NLRDAV N GTI EY T N P a N GK H Y S L DED PATLI C R V RG L HLPEKH ITFN G K 185
Cdd:cd00727 81 INALN SGA KVFMADFED AN APTW ENQVE GQ I NLRDAV R GTI SF T S P - E GK E Y K L NDT PATLI V R P RG W HLPEKH VLVD G E 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 186 I V P G C L V DF A L F F SN N YEE LLA K G A GPYFY V PK LQ SH H E SKW W SE VF SY A E D KVN L A RGTIKAT L LIET I PA V FEM E EIL 265
Cdd:cd00727 160 P V S G S L F DF G L Y F FH N AKA LLA R G S GPYFY L PK ME SH L E ARL W ND VF VF A Q D YLG L P RGTIKAT V LIET L PA A FEM D EIL 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 266 Y SMKE H IVA LNCGRWDYIFS Y IK TL R K H A D R VLPDR HS VTM DKT F LS AYS R LLI R TCH K RGA L AMGGMAA F IP A K - TAEE 344
Cdd:cd00727 240 Y ELRD H SAG LNCGRWDYIFS F IK KF R N H P D F VLPDR AQ VTM TVP F MR AYS E LLI K TCH R RGA H AMGGMAA Q IP I K d DPAA 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 345 N DKV L T KV T ADK TL EA QN GHDGTWVAHPGL ADT AM G V MNEYIGE gn A NQ IQ V S R a D D AP VTAA E LL Q - P CD G ER TE A G M R 423
Cdd:cd00727 320 N EAA L A KV R ADK LR EA TA GHDGTWVAHPGL VPV AM E V FDKHMPG -- P NQ LD V L R - E D VK VTAA D LL L v P VE G GI TE E G L R 396
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 424 L NI RI G VR Y ME AW IS GNGCVPIY G LMEDAATAEISRA SI WQWI Q HG KT - L SN G KV VT K EL FSQ LL Q EEL VVIR d E E I G VE 502
Cdd:cd00727 397 Q NI SV G LQ Y LA AW LR GNGCVPIY N LMEDAATAEISRA QL WQWI R HG VR l L DD G RP VT A EL VEK LL A EEL AKLK - A E V G QA 475
490 500 510
....*....|....*....|....*....|....*.
gi 518270166 503 AYENS R F AEA SK LFEEL TISDHLA EFLTLP G YD F L D 538
Cdd:cd00727 476 GFATG R L AEA AE LFEEL VTAEEFP EFLTLP A YD D L V 511
malate_syn_A
TIGR01344 malate synthase A; This model represents plant malate synthase and one of two bacterial forms, ...
26-537
0e+00
malate synthase A; This model represents plant malate synthase and one of two bacterial forms, designated malate synthase A. The distantly related malate synthase G is described by a separate model. This enzyme and isocitrate lyase are the two characteristic enzymes of the glyoxylate shunt. The shunt enables the cell to use acetyl-CoA to generate increased levels of TCA cycle intermediates for biosynthetic pathways such as gluconeogenesis. [Energy metabolism, TCA cycle]
Pssm-ID: 188132
Cd Length: 511
Bit Score: 814.81
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 26 I L N P A A VAL L TE L VEK F A P QV D E LL NQ R VKK QA RM D A G E LPDFLPETA H IRE G DW K I QG IP AK LQDRRVEITGPVDRKMV 105
Cdd:TIGR01344 1 V L T P E A LEF L AL L HRR F N P RR D Q LL AR R SNR QA KI D S G Y LPDFLPETA Q IRE D DW T I AP IP PD LQDRRVEITGPVDRKMV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 106 INALNA RV KVFMADFEDS FA PTW AG V LD GQ V NLRDA VN G T I EY T N P AN GK H Y S L DEDP A T LI C R V RG L HLPE K H I T FN G K 185
Cdd:TIGR01344 81 INALNA GA KVFMADFEDS SS PTW EN V IY GQ I NLRDA IR G Q I DF T D P TS GK E Y A L NARL A V LI V R P RG W HLPE R H L T ID G E 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 186 IV PG C L V DF A L F F SN N YEE LL A KG A GPYFY V PKL Q SH H E SKW W SE VF SY A E D KVN L A RGTIKAT L LIET I PA V FEM E EIL 265
Cdd:TIGR01344 161 AI PG S L F DF G L Y F FH N ARA LL K KG K GPYFY L PKL E SH Q E ARL W ND VF HF A Q D FLG L P RGTIKAT V LIET L PA A FEM D EIL 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 266 Y SMK EHI VA LNCGRWDYIFS Y IKTLR KHADR VLPDR HS VTM D K T FL S AYS R LLI R TCH K RGA L AMGGMAAFIP A K TAEE - 344
Cdd:TIGR01344 241 Y ELR EHI SG LNCGRWDYIFS F IKTLR NLPEF VLPDR DA VTM T K P FL N AYS K LLI Q TCH R RGA H AMGGMAAFIP I K GDPA a 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 345 N DKVLT KV T ADK TL EA Q NGHDGTWVAHP G L ADT AM G V M N EYI G E gn A NQ IQVS R AD D APV TAAELL QPC DG E RTEAG M R L 424
Cdd:TIGR01344 321 N EAAFN KV R ADK IR EA K NGHDGTWVAHP D L VPV AM E V F N NVM G T -- P NQ LDRV R DE D VSI TAAELL AVP DG S RTEAG L R H 398
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 425 NIR I G VR Y M EAW IS G N GCVPIY G LMEDAATAEISRA SI WQWI Q HG KT L SN G K VVT K ELF SQ LL QE E LVVI R d E E I G V E AY 504
Cdd:TIGR01344 399 NIR V G LQ Y I EAW LR G S GCVPIY H LMEDAATAEISRA QL WQWI K HG VV L DD G R VVT P ELF RD LL NQ E MGKL R - S E S G L E EF 477
490 500 510
....*....|....*....|....*....|...
gi 518270166 505 ENS RF A EA S KLF EE L TI S DH L AE FLT L P G YD F L 537
Cdd:TIGR01344 478 AAG RF E EA A KLF LR L VT S KE L ED FLT I P A YD E L 510
malate_synt
cd00480 Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , ...
31-537
0e+00
Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238267
Cd Length: 511
Bit Score: 740.59
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 31 A V A LLT EL VEK F A P QVD ELL NQ R VKK QAR M DAG E - LPDFLPETA H IR E - GDWK IQGI P AK L Q DRRVEITGP V DRKMVINA 108
Cdd:cd00480 1 A L A FVA EL HRE F N P RRR ELL AA R DER QAR L DAG H a LPDFLPETA Y IR R d GDWK VAPD P PD L D DRRVEITGP Q DRKMVINA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 109 LN ARVK VFMADFEDS F APTW AGVLD GQ V NL R DAV N GTI EY T NPA NGK H Y S L -- DEDP ATL IC R V RG L HL P EKHI TFN G KI 186
Cdd:cd00480 81 LN SGAA VFMADFEDS S APTW ENKVE GQ R NL L DAV R GTI SF T DSK NGK S Y R L nl LDGR ATL FV R P RG W HL T EKHI LVD G EP 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 187 VPG C L V DF A L F F SN N YEE L L A K G A GPYFY V PK LQ S HH E SKW W SE VFS Y AED KVN L A RGTIKAT L LIET I PA V FEM E EILY 266
Cdd:cd00480 161 VPG G L F DF G L Y F FH N AHA L K A R G S GPYFY L PK ME S PL E ARL W ND VFS R AED YLG L P RGTIKAT V LIET L PA A FEM D EILY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 267 SMKE H IVA LNCGRWDYIFS Y IKT L R K H A D R VLPDR HS VTM DKT F LS AY SR LL IR TCH K RGA L AMGGMAA F IP A K T - AEE N 345
Cdd:cd00480 241 ELRD H SAG LNCGRWDYIFS E IKT F R N H P D F VLPDR AK VTM TSP F MR AY EK LL VK TCH R RGA H AMGGMAA Q IP I K G d PAA N 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 346 DKVLT KV T ADK TL EA QN GHDGTWVAHPGLA DT A MG V MNEYIGE gn A NQ IQVS R a D D AP VTA AE LL Q -- PCD G ER TE A G M R 423
Cdd:cd00480 321 EAAMA KV R ADK LR EA KA GHDGTWVAHPGLA PL A AL V FHKVMPG -- P NQ LFRK R - E D VK VTA DD LL T ip VAE G DI TE E G L R 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 424 L NI RIGVR Y ME AW IS GNG C VPI YG LMEDAATAEISR ASI WQW IQ HG KT L SN G KV VT K EL FSQ L LQ EE LVVIR d EEIGVEA 503
Cdd:cd00480 398 N NI QVALG Y VV AW LN GNG A VPI IN LMEDAATAEISR SQL WQW LR HG VC L DD G VP VT L EL VAK L VD EE NARLP - AYRPPNF 476
490 500 510
....*....|....*....|....*....|....
gi 518270166 504 YENSR F A EA SK LF E E LTISDHLA EFLT L P G Y DF L 537
Cdd:cd00480 477 FDSIA F K EA AD LF F E GVTAEEFP EFLT E P L Y HL L 510
Malate_synthase
pfam01274 Malate synthase;
15-537
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 739.98
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 15 F H G EINQEQQQ IL NPA A VALLT EL VEK F A P QVD ELL NQ R VKK QAR M DAG E LPDFLPET AH IR - EG DWK IQGIPAK LQDRR 93
Cdd:pfam01274 3 F V G PYVLPGTG IL TKE A LSFVA EL HRD F T P RRR ELL AR R DER QAR I DAG H LPDFLPET GY IR p DP DWK TATLHPE LQDRR 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 94 VEITGP V DRKM V INALN ARVKVF MADFEDS F APTW AGVLD GQ V NL R DAV N G T I EYTNPAN GK H Y S L --- DEDP ATL IC R V 170
Cdd:pfam01274 83 VEITGP A DRKM I INALN SGAITT MADFEDS V APTW NNLIQ GQ L NL Y DAV R G R I DFRDLNA GK S Y K L ndg LHGR ATL FV R P 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 171 RG L HLPEKHI TFN G KIV PG CLV DF A L F F SN N YE EL LAK G A GPYFY V PK LQS H H E SKW W SE VF SY AED KVNLA RGTI K AT L 250
Cdd:pfam01274 163 RG W HLPEKHI LVD G EPI PG GIF DF G L Y F FH N AK EL NSR G G GPYFY L PK MEH H Q E AAL W ND VF NR AED YLGIP RGTI R AT V 242
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 251 LIET I PA V F E M E EI L Y SMKE H IVA LNCGRWDYIFSYIKTLR KHA D R VLPDR HS VTM DKT F LS AY SR LLI R TCHKRG AL AM 330
Cdd:pfam01274 243 LIET L PA S F Q M D EI I Y ELRD H SAG LNCGRWDYIFSYIKTLR NAP D M VLPDR KA VTM TAP F MR AY EK LLI K TCHKRG VH AM 322
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 331 GGMAA F IP A K TAE E - N DKVLT KV T ADK TL E AQN GHDGTWVAHPGLA DT A MG V MNEYI ge GNA NQI QVS R AD D a PV TA AE L 409
Cdd:pfam01274 323 GGMAA Q IP I K DDM E a N TAAME KV R ADK LR E VRA GHDGTWVAHPGLA PL A AE V FHQVM -- VRP NQI ELA R EE D - SI TA DD L 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 410 L QPC DGE R TE A G M R L NI RI G VR Y M EAW IS G N GCVPI YG LMEDAATAEISR ASI WQW IQ HG K TL SN G KV VT K EL FSQ L LQ E 489
Cdd:pfam01274 400 L TIP DGE E TE E G L R N NI QV G LQ Y V EAW LR G S GCVPI IH LMEDAATAEISR QQL WQW LR HG V TL DE G VR VT L EL MAK L VD E 479
490 500 510 520
....*....|....*....|....*....|....*....|....*...
gi 518270166 490 E L vvird EEIGV E AYENSRFAE A SK LF EELTISDHLAE FLTL PG YD F L 537
Cdd:pfam01274 480 E N ----- ARLAK E RFGDGAYRD A AR LF LQQATAEEYDD FLTL LA YD D L 522
PLN02626
PLN02626 malate synthase
16-535
0e+00
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 715.78
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 16 H G EINQ E QQQ IL NPA A VALLTE L VEK F A P QVDE LL NQ R VKK Q A R M DAG E LP D F L P E T AHI REGDW KIQGI P AKLQ DRRVE 95
Cdd:PLN02626 15 R G PYDA E FAK IL TRD A LQFVAD L QRE F R P RRKY LL EC R REA Q R R Y DAG A LP G F D P A T RAV REGDW RCAPV P PAVA DRRVE 94
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 96 ITGPV D RKMVINALN ARV KVFMADFEDS FA PTW AGVLD GQVNLRDAV N GTI EY T NP A N GK H Y S L DEDP A T L IC R V RG L HL 175
Cdd:PLN02626 95 ITGPV E RKMVINALN SGA KVFMADFEDS LS PTW ENLMR GQVNLRDAV R GTI TF T DK A R GK V Y K L NDKT A K L FV R P RG W HL 174
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 176 PE K HI TFN G KIVP G C L V DF A L F F SN NY EELL AK -- G A GP Y FY V PK LQSHH E SKW W SE VF SY AE DKVNLA RG T I K AT L LIE 253
Cdd:PLN02626 175 PE A HI LVD G EPAT G S L F DF G L Y F FH NY AAFR AK qg G F GP F FY L PK MEHSR E ARL W ND VF EA AE KMAGIP RG S I R AT V LIE 254
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 254 T I PAVF E MEEILY SMKE H IVA LNCGRWDYIFS YI KT L R K H A DR V LPDR HS V T M DKT F LSA Y SR LLI R TCHKRG AL AMGGM 333
Cdd:PLN02626 255 T L PAVF Q MEEILY ELRD H SAG LNCGRWDYIFS FV KT F R A H P DR L LPDR VQ V G M TQH F MKS Y VD LLI K TCHKRG VH AMGGM 334
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 334 AA F IP A K - TAEE N DKV L TK V TA DK TL E AQN GHDGTW V AHPGL ADT AM G V MNEYI ge GNA N QI Q - VS R A DD AP VT A A E LLQ 411
Cdd:PLN02626 335 AA Q IP I K d DPAA N EAA L AL V RK DK LR E VRA GHDGTW A AHPGL IPL AM E V FDGHM -- PTP N NQ Q l HK R R DD VN VT E A D LLQ 412
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 412 PCD G E RT EA G M RLN I R I G VR Y ME AW IS G N G C VP I Y G LMEDAATAEISR ASI WQWI QH G KT L SNGK V --- VT K ELF SQLLQ 488
Cdd:PLN02626 413 VPR G V RT LE G L RLN T R V G IQ Y LA AW LT G T G S VP L Y N LMEDAATAEISR VQN WQWI KY G AE L DGDG V gvr VT A ELF GRVVE 492
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 518270166 489 EE LVV I r DE E I G V E AYENSRFA EA S KLF EELTISDH L AE FLTL PG Y D 535
Cdd:PLN02626 493 EE MAR I - ER E V G K E RFKKGKYK EA A KLF ARQCTAPE L DD FLTL DA Y N 538
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
119-505
4.88e-06
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 49.33
E-value: 4.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 119 D F EDS F A PT ----------- W A G VLD G QVNLRDAV NG TIEYTNPANGKH Y - SL D EDPA TL IC R ---- VR GL - HL PEKH -- 179
Cdd:cd00728 264 D C EDS V A AV daedkvlvyrn W L G LMK G DLAEEVEK NG RTFTRKLNADRN Y t TP D GGEI TL PG R slmf VR NV g HL MTND ai 343
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 180 ITFN G KI VP GCLV D f A LFF S nnyee L L A ---- KG AGPY ------- F Y V -- PK LQSHH E SKWWS E V FS YA ED KVN L ARG TI 246
Cdd:cd00728 344 LDSD G NE VP EGIM D - A VIT S ----- L I A lhdl KG NSAF gnsrtgs I Y I vk PK MHGPE E VAFAN E L FS RV ED LLG L PQN TI 417
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 247 K ATLLI E TIPAVFEME E ILYSMKEHI V AL N C G RW D YIFSY I K T l RKH A DRVL pd R HSVTMDKTFLS AY SRLLIRT --- CH 323
Cdd:cd00728 418 K MGIMD E ERRTSVNLK E CIRAARDRV V FI N T G FL D RTGDE I H T - SME A GPMA -- R KADMKSSPWIG AY EDNNVDI gla AG 494
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 324 KR G ALAM G - GM A A f I P AKT A E endkvltk VTAD K TLEAQN G HDGT WV AH P GL A D --------- TAMG V MN E YIGEGN A NQ 393
Cdd:cd00728 495 LS G KAQI G k GM W A - M P DLM A D -------- MMEQ K IAHPKA G ANTA WV PS P TA A T lhalhyhqv NVFA V QK E LAKRRP A DL 565
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518270166 394 --- IQVSR A DD A PVTAA E LLQPC D G erteagmrl N IRIGVR Y MEA W IS - G N GC -- VP - I Y -- GLMED A AT AE IS RAS I WQ 464
Cdd:cd00728 566 ddl LTIPL A EN A NWSPQ E IQSEL D N --------- N VQGILG Y VVR W VD q G I GC sk VP d I N nv GLMED R AT LR IS SQH I AN 636
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 518270166 465 W IQ HG ktlsngk VV TKE LFSQL L QEELV V IRDEEI G VEA Y E 505
Cdd:cd00728 637 W LR HG ------- IC TKE QVQES L ERMAK V VDQQNA G DPS Y R 670
PRK02999
PRK02999 malate synthase G; Provisional
430-481
9.20e-03
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 39.00
E-value: 9.20e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 518270166 430 VR ymea W I - S G N GC -- VP - I Y -- GLMED A AT AE IS RAS I WQ W IQ HG ktlsngk VVT K E 481
Cdd:PRK02999 609 VR ---- W V d Q G V GC sk VP d I H dv GLMED R AT LR IS SQH I AN W LR HG ------- VVT E E 655
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
