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Conserved domains on  [gi|518283431|ref|WP_019453639|]
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MULTISPECIES: ABC transporter permease [Serratia]

Protein Classification

ABC transporter permease( domain architecture ID 11468042)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs; similar to microcin C transport system permease protein YejE

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 594.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431   1 MSRLSPINQARWARFRRNRRGYWSLWIFLVLFTLSLAADLIANDKPLLVRYEGRLYLPFMINYSETAFGGELSTEADYQD 80
Cdd:COG4239    1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  81 PFVQRQIERHGWAVWAPIRFSYDTINFATEVPFPSPPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVC 160
Cdd:COG4239   81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 161 VGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARA 240
Cdd:COG4239  161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 241 MGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITAFLVLAVL 320
Cdd:COG4239  241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                        330       340
                 ....*....|....*....|
gi 518283431 321 LSLLIFIGEAVRDAFDPSKA 340
Cdd:COG4239  321 LSLLVFIGEAVRDAFDPRKT 340
 
Name Accession Description Interval E-value
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 594.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431   1 MSRLSPINQARWARFRRNRRGYWSLWIFLVLFTLSLAADLIANDKPLLVRYEGRLYLPFMINYSETAFGGELSTEADYQD 80
Cdd:COG4239    1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  81 PFVQRQIERHGWAVWAPIRFSYDTINFATEVPFPSPPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVC 160
Cdd:COG4239   81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 161 VGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARA 240
Cdd:COG4239  161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 241 MGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITAFLVLAVL 320
Cdd:COG4239  241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                        330       340
                 ....*....|....*....|
gi 518283431 321 LSLLIFIGEAVRDAFDPSKA 340
Cdd:COG4239  321 LSLLVFIGEAVRDAFDPRKT 340
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-340 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 575.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431   1 MSRLSPINQARWARFRRNRRGYWSLWIFLVLFTLSLAADLIANDKPLLVRYEGRLYLPFMINYSETAFGGELSTEADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  81 PFVQRQIERHGWAVWAPIRFSYDTINFATEVPFPSPPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVC 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 161 VGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 241 MGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITAFLVLAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|
gi 518283431 321 LSLLIFIGEAVRDAFDPSKA 340
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKA 340
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 167-314 1.70e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 76.18  E-value: 1.70e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  167 YYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQP----NFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARAMG 242
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILsilgHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALG 90

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518283431  243 VSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITAF 314
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALI 162
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 140-314 2.40e-16

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 76.16  E-value: 2.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 140 FRISMLFGLALTLFSSLIGVCVGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLL--------GITI 211
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGIlpglglpaLILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 212 LFGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPigsP 291
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA---P 157

                        170       180
                 ....*....|....*....|...
gi 518283431 292 SLGELLLQGKNNLQAPWLGITAF 314
Cdd:cd06261  158 GPGTGLLLIFAILFPGDLGVAAA 180
 
Name Accession Description Interval E-value
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 1-340 0e+00

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 594.44  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431   1 MSRLSPINQARWARFRRNRRGYWSLWIFLVLFTLSLAADLIANDKPLLVRYEGRLYLPFMINYSETAFGGELSTEADYQD 80
Cdd:COG4239    1 MMRLSPLNRRRWRRFKANRRGYWSLWIFLVLFVLSLFAELIANDKPLLVSYDGELYFPVLKDYPETTFGGDFETEADYRD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  81 PFVQRQIERHGWAVWAPIRFSYDTINFATEVPFPSPPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVC 160
Cdd:COG4239   81 PFVQELIEAKGWALWPPIPYSYDTINYDLPSPAPSPPSAENWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 161 VGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARA 240
Cdd:COG4239  161 AGAVQGYFGGRVDLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 241 MGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITAFLVLAVL 320
Cdd:COG4239  241 LGVSDRRIMFRHILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQAPWLGLSAFVVLALM 320

                        330       340
                 ....*....|....*....|
gi 518283431 321 LSLLIFIGEAVRDAFDPSKA 340
Cdd:COG4239  321 LSLLVFIGEAVRDAFDPRKT 340
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 1-340 0e+00

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 575.01  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431   1 MSRLSPINQARWARFRRNRRGYWSLWIFLVLFTLSLAADLIANDKPLLVRYEGRLYLPFMINYSETAFGGELSTEADYQD 80
Cdd:PRK15021   1 MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  81 PFVQRQIERHGWAVWAPIRFSYDTINFATEVPFPSPPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVC 160
Cdd:PRK15021  81 PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 161 VGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARA 240
Cdd:PRK15021 161 AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 241 MGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITAFLVLAVL 320
Cdd:PRK15021 241 LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL 320

                        330       340
                 ....*....|....*....|
gi 518283431 321 LSLLIFIGEAVRDAFDPSKA 340
Cdd:PRK15021 321 LSLLIFIGEAVRDAFDPNKA 340
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 92-336 1.35e-61

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 198.03  E-value: 1.35e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  92 WAVWAPIRFSYDTINFATEVPFpSPPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYYGGR 171
Cdd:COG1173   31 LALFAPLLAPYDPTAQDLAARL-QPPSAAHWLGTDQLGRDVLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGW 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 172 FDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSR 251
Cdd:COG1173  110 VDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFR 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 252 HMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQ-APWLGITAFLVLAVLLSLLIFIGEA 330
Cdd:COG1173  190 HILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEGRNYLLtAPWLALFPGLAIVLTVLAFNLLGDG 269


                 ....*.
gi 518283431 331 VRDAFD 336
Cdd:COG1173  270 LRDALD 275
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 94-337 4.16e-30

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 116.47  E-value: 4.16e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  94 VWAPI--RFSYDTINFATEVPFPSPPSRHnLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYYGGR 171
Cdd:PRK15406  54 ILAPMlsQFAYDDTDWGMMSSAPDMESGH-YFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGK 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 172 FDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSR 251
Cdd:PRK15406 133 VDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLR 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 252 HMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQ-APWLGITAFLVLAVLLSLLIFIGEA 330
Cdd:PRK15406 213 HIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEvSPWLLLFPAGFLVVTLFCFNFIGDG 292


                 ....*..
gi 518283431 331 VRDAFDP 337
Cdd:PRK15406 293 LRDALDP 299
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 93-337 1.31e-21

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 93.25  E-value: 1.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  93 AVWAPIRFSYDTINFATEVPFPSPPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYYGGRF 172
Cdd:PRK15082  52 AIFAPWIAPYDAENYFDYDALNAGPSLQHWFGVDSLGRDIFSRILVGARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWW 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 173 DLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSRH 252
Cdd:PRK15082 132 DRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFARLVRGNTLVLKQQTYIESARSIGASDWTILLRH 211

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 253 MLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNL-QAPWLGITAFLVLAVLLSLLIFIGEAV 331
Cdd:PRK15082 212 ILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNEARADMvIAPHVALFPSLAIFLTVLAFNLLGDGL 291


                 ....*.
gi 518283431 332 RDAFDP 337
Cdd:PRK15082 292 RDALDP 297
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
116-337 1.74e-20

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 89.88  E-value: 1.74e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 116 PPSRHNLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILL 195
Cdd:PRK09881  69 PPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMAL 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 196 SSIVQPNFW-WLLGITILfGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSRHMLPNAMVATLTFLPFILCGSIT 274
Cdd:PRK09881 149 AAALGPSLFnAMLAIAIV-RIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAIL 227

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 518283431 275 TLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLgITAFLVLAVLLSLLIF--IGEAVRDAFDP 337
Cdd:PRK09881 228 MAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWW-YCAFPGAAILLTAVGFnlFGDGIRDLLDP 291
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
122-337 3.38e-18

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 83.68  E-value: 3.38e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 122 LLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQP 201
Cdd:PRK10913  80 ILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGP 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 202 NfwwLLGITILFGWMSL---VGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTS 278
Cdd:PRK10913 160 S---IVNAALALTFVALphyVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAA 236

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 518283431 279 LDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITaFLVLAVLLSLLIF--IGEAVRDAFDP 337
Cdd:PRK10913 237 LGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVT-FPGLAILLTVLAFnlMGDGLRDALDP 296
nikC PRK10417
nickel transporter permease NikC; Provisional
 93-337 4.44e-17

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 79.71  E-value: 4.44e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  93 AVWAPIRFSYDTinFATEVP--FPSPPSRHnLLGTDSNGGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYYGG 170
Cdd:PRK10417  20 ALTSQWWLPYDP--QAIDLPsrLLSPDAQH-WLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVLALGLVIGGSAGLLGG 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 171 RFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMS 250
Cdd:PRK10417  97 RVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFVLAARLSGAGHVRVFI 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 251 RHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKN-----NLQAPWLGITAFLVLAVLLSlli 325
Cdd:PRK10417 177 DHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQyiwtqPLLMFWPGLALFISVMAFNL--- 253

                        250
                 ....*....|..
gi 518283431 326 fIGEAVRDAFDP 337
Cdd:PRK10417 254 -LGDALRDHLDP 264
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 167-314 1.70e-16

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 76.18  E-value: 1.70e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431  167 YYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQP----NFWWLLGITILFGWMSLVGVVRAEFLRTRNYDYIRAARAMG 242
Cdd:pfam00528  11 RRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILsilgHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALG 90

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518283431  243 VSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPIGSPSLGELLLQGKNNLQAPWLGITAF 314
Cdd:pfam00528  91 ASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALI 162
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 140-314 2.40e-16

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 76.16  E-value: 2.40e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 140 FRISMLFGLALTLFSSLIGVCVGATQGYYGGRFDLWGQRFIEVWSGMPTLFLIILLSSIVQPNFWWLL--------GITI 211
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGIlpglglpaLILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 212 LFGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSRHMLPNAMVATLTFLPFILCGSITTLTSLDFLGFGLPigsP 291
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA---P 157

                        170       180
                 ....*....|....*....|...
gi 518283431 292 SLGELLLQGKNNLQAPWLGITAF 314
Cdd:cd06261  158 GPGTGLLLIFAILFPGDLGVAAA 180
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 127-275 9.10e-11

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 62.01  E-value: 9.10e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 127 SNGGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYY-GGRFDLWGQRFIEVWSGMPTLFLIILLSSI------- 198
Cdd:COG0601   82 VYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRrGSWLDRLITVLALLGISIPSFWLGLLLILLfavklgw 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 199 --------VQPNFW------WLLGITILFGWMSLVG-VVRAEFLRTRNYDYIRAARAMGVSDRVIMSRHMLPNAMVATLT 263
Cdd:COG0601  162 lpvsgrvsPWEDFLdalrhlILPALTLALGSLAGIArLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241

                        170
                 ....*....|....*.
gi 518283431 264 F----LPFILCGSITT 275
Cdd:COG0601  242 VlglqLGGLLGGAVVV 257
PRK15111 PRK15111
peptide ABC transporter permease SapC;
123-308 2.57e-06

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 48.54  E-value: 2.57e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 123 LGTDSNGGDVLARVLYG----FRISMLFGLALTLFSSLIGVCVGATQGYYGGRFDlwgqRFIEVWSGMPTLFLIILLSSI 198
Cdd:PRK15111  78 LGTDDLGRDVLSRLLSGaaptVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLN----HILDTLLSIPSLLLAIIVVAF 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 199 VQPNfwwlLGITILFGWMSLVG-VVRAEFLRTR---NYDYIRAARAMGVSDRVIMSRHMLPNAMVATLTFLPFILCGSIT 274
Cdd:PRK15111 154 AGPS----LSHAMFAVWLALLPrMVRSIYSAVHdelEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAIL 229

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 518283431 275 TLTSLDFLGFGLPIGSPSLGELLlqgKNNLQ----APW 308
Cdd:PRK15111 230 DIAALGFLDLGAQLPSPEWGAML---GDSLEliyvAPW 264
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 129-283 5.97e-06

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 47.43  E-value: 5.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 129 GGDVLARVLYGFRISMLFGLALTLFSSLIGVCVGATQGYYGG-RFDLWGQRFIEVWSGMPT-LFLIIL------------ 194
Cdd:PRK15133 122 SASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGsRFDVWSSAFIIIGYAIPAfLFAILLivffaggsyfdl 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518283431 195 --LSSIVQPNF----W--------WLLGI----TILFGWMSLVGVVRAEFLRTRNYDYIRAARAMGVSDRVIMSRHMLPN 256
Cdd:PRK15133 202 fpLRGLVSANFdslpWyqkitdylWHITLpvlaTVIGGFAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRN 281

                        170       180       190
                 ....*....|....*....|....*....|....
gi 518283431 257 AMVATL-----TFLPFILCGS--ITTLTSLDFLG 283
Cdd:PRK15133 282 AMLLVIagfpaTFISMFFTGSllIEVMFSLNGLG 315
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 223-285 1.31e-05

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 46.25  E-value: 1.31e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518283431 223 RAEFLRTRNYDYIRAARAMGVSDRVIMSRHMLPNAMVATLTFL----PFILCGSITTLTSLDFLGFG 285
Cdd:PRK15081 193 RASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMglqfGFLLGGSIVVEKVFNWPGLG 259
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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