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Conserved domains on  [gi|518298651|ref|WP_019468859|]
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MULTISPECIES: L-lactate permease [Staphylococcus]

Protein Classification

L-lactate permease( domain architecture ID 10004073)

L-lactate permease plays a role in L-lactate utilization by transporting L-lactate across the membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
11-533 4.33e-160

L-lactate permease [Energy production and conversion];


:

Pssm-ID: 441227  Cd Length: 520  Bit Score: 465.76  E-value: 4.33e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  11 NVLLSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIiPIGYIVIMAVLLYK 90
Cdd:COG1620    2 SLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGL-PILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  91 VTNETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGAFGA 170
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 171 IGLPVTVidtLGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIGPEL 250
Cdd:COG1620  161 VGTPIIV---GAQVTGLDALEIGAMVGRQLPILSLLIPFLLVWILDGWRGIKEVWPAALVAGLSFAVPQFLTANFLGPEL 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 251 ADIIPPLVSMLALALYSKKHQPKNIFRLKDSG----EPKSIVKHNFKTLIYAWSPFVILTALVMIWSA-PQFKALfspng 325
Cdd:COG1620  238 PDIIAGLVGLAALVLFLRFWKPKEIWDFAPEEewpaEEEDAEKLSAMSLLKAWSPYLLLIVLLVLTRLpPPVKAL----- 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 326 aLSALVFNIQLPGtYSDIADKAITLPLNIIGQTGTAILLVILITILMSKqVNMLDATRLLKLTFKELWLPIITICIILII 405
Cdd:COG1620  313 -LNSTTLKIPWPG-LLGAGTTGASYSFNPLYAPGTAILLAALITILLLR-MSPGQAKRAFKETLKQLRGPILTLAFVLAL 389
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 406 SKLMTYAGLSNALGEGIA-KAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNIGTSGALLVSANTVGGVAAK 484
Cdd:COG1620  390 AYVMNYSGMPATLGLALAaATGAAFPFFAPFLGWLGVFITGSDTSSNALFGGLQFTTAEQLGLSPTLIVAAQSVGGVMGK 469
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*....
gi 518298651 485 LISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNFII 533
Cdd:COG1620  470 MISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
11-533 4.33e-160

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 465.76  E-value: 4.33e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  11 NVLLSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIiPIGYIVIMAVLLYK 90
Cdd:COG1620    2 SLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGL-PILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  91 VTNETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGAFGA 170
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 171 IGLPVTVidtLGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIGPEL 250
Cdd:COG1620  161 VGTPIIV---GAQVTGLDALEIGAMVGRQLPILSLLIPFLLVWILDGWRGIKEVWPAALVAGLSFAVPQFLTANFLGPEL 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 251 ADIIPPLVSMLALALYSKKHQPKNIFRLKDSG----EPKSIVKHNFKTLIYAWSPFVILTALVMIWSA-PQFKALfspng 325
Cdd:COG1620  238 PDIIAGLVGLAALVLFLRFWKPKEIWDFAPEEewpaEEEDAEKLSAMSLLKAWSPYLLLIVLLVLTRLpPPVKAL----- 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 326 aLSALVFNIQLPGtYSDIADKAITLPLNIIGQTGTAILLVILITILMSKqVNMLDATRLLKLTFKELWLPIITICIILII 405
Cdd:COG1620  313 -LNSTTLKIPWPG-LLGAGTTGASYSFNPLYAPGTAILLAALITILLLR-MSPGQAKRAFKETLKQLRGPILTLAFVLAL 389
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 406 SKLMTYAGLSNALGEGIA-KAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNIGTSGALLVSANTVGGVAAK 484
Cdd:COG1620  390 AYVMNYSGMPATLGLALAaATGAAFPFFAPFLGWLGVFITGSDTSSNALFGGLQFTTAEQLGLSPTLIVAAQSVGGVMGK 469
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*....
gi 518298651 485 LISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNFII 533
Cdd:COG1620  470 MISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
14-529 5.95e-140

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 414.47  E-value: 5.95e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   14 LSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIIPIGYIVIMAVLLYKVTN 93
Cdd:pfam02652   1 LSALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLWPIAWIIIAAIFLYKISV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   94 ETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGAFGAIGL 173
Cdd:pfam02652  81 KSGAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  174 PVTvidTLGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIGPELADI 253
Cdd:pfam02652 161 PIT---AGAGATGLSALEISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETFPAVLVSGLSFAIPQFLSSNVLGPELPSI 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  254 IPPLVSMLALALYSKKHQPKNIFRLKDSGEPKSIVKHNFKTLIYAWSPFVILTALVMIWSAPQFKALFSPNGALSALVFN 333
Cdd:pfam02652 238 LGALVSLVITALFLKFWQPKEIFRFAGKGDSGATSALRAGKIVKAWSPFVLLTAFIVLWSIPQFKALFQEGGALYTSTFN 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  334 ----------IQLPGTYSDIADKAITLPLNIIGQTGTAILLVILITILMSKqVNMLDATRLLKLTFKELWLPIITICIIL 403
Cdd:pfam02652 318 fefpeisqliFSIPPIVGEATPFPVVFKFKLLYSPGTIIFLAALLSIFILK-VSSSDALSIFKETLKEMALPIITIIFVL 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  404 IISKLMTYAGLSNALGEGIAKAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNIGTSGALLVSANTVGGVAA 483
Cdd:pfam02652 397 AFANLMNYSGMSKTLALALAHTGSAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMG 476
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 518298651  484 KLISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFML 529
Cdd:pfam02652 477 KMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAIIVGVVAFLL 522
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
14-531 2.28e-138

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 410.63  E-value: 2.28e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   14 LSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIIPIGYIVIMAVLLYKVTN 93
Cdd:TIGR00795   7 LSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLWPIAWIIIAAIFLYKLSV 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   94 ETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGAFGAIGL 173
Cdd:TIGR00795  87 KSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  174 PVTVidtLGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIGPELADI 253
Cdd:TIGR00795 167 PIWA---GAQATGLSALEISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETFPAVLVAGLSFAIPQFLSSNYLGPELPSI 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  254 IPPLVSMLALALYSKKHQPKNIFRLKDSGEPKSIVKHNFKTLIYAWSPFVILTALVMIWSAPQFKALFSPNGALSALVFN 333
Cdd:TIGR00795 244 LGALVSLVITALFLKFWQPKEIFRFNGKLDAGEVSAHHICKIVKAWSPFVLLTAFIVLWSIPPFKALFMKGGALIFSSFT 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  334 IQLPGTYSDIADKAITLP----------LNIIGQTGTAILLVILITILmSKQVNMLDATRLLKLTFKELWLPIITICIIL 403
Cdd:TIGR00795 324 FGSPGLSQHIFKLPPIVNqatnfpavfkLLLIIATGTSILLAAIVSFF-ILRVSISDAIGVFGETLKEMRLPILTIGMVL 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  404 IISKLMTYAGLSNALGEGIAKAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNIGTSGALLVSANTVGGVAA 483
Cdd:TIGR00795 403 AFANVSNYSGMSKTLALALAHTGLAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGVMG 482
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 518298651  484 KLISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNF 531
Cdd:TIGR00795 483 KMISPQSIAIACAAVGLVGQESDLFRKTVKYSLIYAIIVGVVALLLAY 530
PRK10420 PRK10420
L-lactate permease; Provisional
1-533 9.54e-136

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 404.61  E-value: 9.54e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   1 MFVESINPFNNVLLSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIIPIGY 80
Cdd:PRK10420   3 LWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAW 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  81 IVIMAVLLYKVTNETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLI 160
Cdd:PRK10420  83 IIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLI 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 161 ANASAGAFGAIGLPVTVIdtlGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQA 240
Cdd:PRK10420 163 VNTAPVAFGAMGIPILVA---GQVTGIDSFEIGQMVGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAVVVAGGSFAIAQY 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 241 LITVFIGPELADIIPPLVSMLALALYSKKHQPKNIFRLKDSGE-----PKSIVKHNFKTLIYAWSPFVILTALVMIWSAP 315
Cdd:PRK10420 240 LSSNFIGPELPDIISSLVSLVCLTLFLKRWQPVRIFRFGDLGAsqvdmTLAHTGYTAGQVLRAWSPFLFLTATVTLWSIP 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 316 QFKALFSPNGALSALVFNIQLPGTY----------SDIADKAITLPLNIIGQTGTAILLVILITILMSKqVNMLDATRLL 385
Cdd:PRK10420 320 PFKALFASGGALYEWVINIPVPYLDklvarmppvvSEATAYAAVYKFDWFSATGTAILFAALLSIVWLK-MKPSDAISTF 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 386 KLTFKELWLPIITICIILIISKLMTYAGLSNALGEGIAKAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNI 465
Cdd:PRK10420 399 GSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQI 478
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 518298651 466 GTSGALLVSANTVGGVAAKLISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNFII 533
Cdd:PRK10420 479 GVSDVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVL 546
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
11-533 4.33e-160

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 465.76  E-value: 4.33e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  11 NVLLSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIiPIGYIVIMAVLLYK 90
Cdd:COG1620    2 SLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGL-PILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  91 VTNETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGAFGA 170
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 171 IGLPVTVidtLGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIGPEL 250
Cdd:COG1620  161 VGTPIIV---GAQVTGLDALEIGAMVGRQLPILSLLIPFLLVWILDGWRGIKEVWPAALVAGLSFAVPQFLTANFLGPEL 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 251 ADIIPPLVSMLALALYSKKHQPKNIFRLKDSG----EPKSIVKHNFKTLIYAWSPFVILTALVMIWSA-PQFKALfspng 325
Cdd:COG1620  238 PDIIAGLVGLAALVLFLRFWKPKEIWDFAPEEewpaEEEDAEKLSAMSLLKAWSPYLLLIVLLVLTRLpPPVKAL----- 312
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 326 aLSALVFNIQLPGtYSDIADKAITLPLNIIGQTGTAILLVILITILMSKqVNMLDATRLLKLTFKELWLPIITICIILII 405
Cdd:COG1620  313 -LNSTTLKIPWPG-LLGAGTTGASYSFNPLYAPGTAILLAALITILLLR-MSPGQAKRAFKETLKQLRGPILTLAFVLAL 389
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 406 SKLMTYAGLSNALGEGIA-KAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNIGTSGALLVSANTVGGVAAK 484
Cdd:COG1620  390 AYVMNYSGMPATLGLALAaATGAAFPFFAPFLGWLGVFITGSDTSSNALFGGLQFTTAEQLGLSPTLIVAAQSVGGVMGK 469
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|....*....
gi 518298651 485 LISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNFII 533
Cdd:COG1620  470 MISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
14-529 5.95e-140

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 414.47  E-value: 5.95e-140
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   14 LSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIIPIGYIVIMAVLLYKVTN 93
Cdd:pfam02652   1 LSALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLWPIAWIIIAAIFLYKISV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   94 ETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGAFGAIGL 173
Cdd:pfam02652  81 KSGAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  174 PVTvidTLGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIGPELADI 253
Cdd:pfam02652 161 PIT---AGAGATGLSALEISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETFPAVLVSGLSFAIPQFLSSNVLGPELPSI 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  254 IPPLVSMLALALYSKKHQPKNIFRLKDSGEPKSIVKHNFKTLIYAWSPFVILTALVMIWSAPQFKALFSPNGALSALVFN 333
Cdd:pfam02652 238 LGALVSLVITALFLKFWQPKEIFRFAGKGDSGATSALRAGKIVKAWSPFVLLTAFIVLWSIPQFKALFQEGGALYTSTFN 317
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  334 ----------IQLPGTYSDIADKAITLPLNIIGQTGTAILLVILITILMSKqVNMLDATRLLKLTFKELWLPIITICIIL 403
Cdd:pfam02652 318 fefpeisqliFSIPPIVGEATPFPVVFKFKLLYSPGTIIFLAALLSIFILK-VSSSDALSIFKETLKEMALPIITIIFVL 396
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  404 IISKLMTYAGLSNALGEGIAKAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNIGTSGALLVSANTVGGVAA 483
Cdd:pfam02652 397 AFANLMNYSGMSKTLALALAHTGSAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMG 476
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*.
gi 518298651  484 KLISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFML 529
Cdd:pfam02652 477 KMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAIIVGVVAFLL 522
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
14-531 2.28e-138

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 410.63  E-value: 2.28e-138
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   14 LSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIIPIGYIVIMAVLLYKVTN 93
Cdd:TIGR00795   7 LSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLWPIAWIIIAAIFLYKLSV 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   94 ETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGAFGAIGL 173
Cdd:TIGR00795  87 KSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGI 166
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  174 PVTVidtLGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIGPELADI 253
Cdd:TIGR00795 167 PIWA---GAQATGLSALEISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETFPAVLVAGLSFAIPQFLSSNYLGPELPSI 243
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  254 IPPLVSMLALALYSKKHQPKNIFRLKDSGEPKSIVKHNFKTLIYAWSPFVILTALVMIWSAPQFKALFSPNGALSALVFN 333
Cdd:TIGR00795 244 LGALVSLVITALFLKFWQPKEIFRFNGKLDAGEVSAHHICKIVKAWSPFVLLTAFIVLWSIPPFKALFMKGGALIFSSFT 323
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  334 IQLPGTYSDIADKAITLP----------LNIIGQTGTAILLVILITILmSKQVNMLDATRLLKLTFKELWLPIITICIIL 403
Cdd:TIGR00795 324 FGSPGLSQHIFKLPPIVNqatnfpavfkLLLIIATGTSILLAAIVSFF-ILRVSISDAIGVFGETLKEMRLPILTIGMVL 402
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  404 IISKLMTYAGLSNALGEGIAKAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNIGTSGALLVSANTVGGVAA 483
Cdd:TIGR00795 403 AFANVSNYSGMSKTLALALAHTGLAFTFFSPFLGWLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGVMG 482
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....*...
gi 518298651  484 KLISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNF 531
Cdd:TIGR00795 483 KMISPQSIAIACAAVGLVGQESDLFRKTVKYSLIYAIIVGVVALLLAY 530
PRK10420 PRK10420
L-lactate permease; Provisional
1-533 9.54e-136

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 404.61  E-value: 9.54e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   1 MFVESINPFNNVLLSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIIPIGY 80
Cdd:PRK10420   3 LWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAW 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  81 IVIMAVLLYKVTNETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLI 160
Cdd:PRK10420  83 IIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLI 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 161 ANASAGAFGAIGLPVTVIdtlGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQA 240
Cdd:PRK10420 163 VNTAPVAFGAMGIPILVA---GQVTGIDSFEIGQMVGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAVVVAGGSFAIAQY 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 241 LITVFIGPELADIIPPLVSMLALALYSKKHQPKNIFRLKDSGE-----PKSIVKHNFKTLIYAWSPFVILTALVMIWSAP 315
Cdd:PRK10420 240 LSSNFIGPELPDIISSLVSLVCLTLFLKRWQPVRIFRFGDLGAsqvdmTLAHTGYTAGQVLRAWSPFLFLTATVTLWSIP 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 316 QFKALFSPNGALSALVFNIQLPGTY----------SDIADKAITLPLNIIGQTGTAILLVILITILMSKqVNMLDATRLL 385
Cdd:PRK10420 320 PFKALFASGGALYEWVINIPVPYLDklvarmppvvSEATAYAAVYKFDWFSATGTAILFAALLSIVWLK-MKPSDAISTF 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 386 KLTFKELWLPIITICIILIISKLMTYAGLSNALGEGIAKAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNI 465
Cdd:PRK10420 399 GSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQI 478
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 518298651 466 GTSGALLVSANTVGGVAAKLISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNFII 533
Cdd:PRK10420 479 GVSDVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVL 546
PRK09695 PRK09695
glycolate permease GlcA;
8-532 1.64e-107

glycolate permease GlcA;


Pssm-ID: 182032  Cd Length: 560  Bit Score: 332.41  E-value: 1.64e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651   8 PFNNVLLSSIVAAIPIILFLLCLTIFKMKGIYASITTLVVTLILAITIFKLPMNIATGASIEGFFQGIIPIGYIVIMAVL 87
Cdd:PRK09695  10 PMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGAITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVF 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651  88 LYKVTNETGQFDKIQDSIASVSQDHRIQLLLIGFAFNGFLEGAAGFGVPIAICALLLTQLGFKPLEAAMLCLIANASAGA 167
Cdd:PRK09695  90 LYKLTVASGQFDIIRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLCLIANTAPVA 169
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 168 FGAIGLPVTVIdtlGLPSDVTGFAVSQMSALTLSIMNMFIPFLLVWIIDGFKGIKETLPAILIVGGTFTILQALITVFIG 247
Cdd:PRK09695 170 FGALGVPILVA---GQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWKGVKETWPAALVAGGSFAVTQFFTSNYIG 246
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 248 PELADIIPPLVSMLALALYSKKHQPKNIFRLKDSGEPKSIV-------------KHNFKTLIYAWSPFVILTALVMIWSA 314
Cdd:PRK09695 247 PELPDITSALVSIVSLALFLKVWRPKNTETAISMGQSAGAMvvnkpssggpvpsEYSLGQIIRAWSPFLILTVLVTIWTM 326
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 315 PQFKALFSPNGALSALVFNIQLPGTYSDIADKAITL----PLNIIGQ-----TGTAILLVILITILMSKQVNMLDATRLL 385
Cdd:PRK09695 327 KPFKALFAPGGAFYSLVINFQIPHLHQQVLKAAPIVaqptPMDAVFKfdplsAGGTAIFIAAIISIFILGVGIKKGIGVF 406
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518298651 386 KLTFKELWLPIITICIILIISKLMTYAGLSNALGEGIAKAGSIFPLLSPILGWIGVFLTGSVTNNNTLFAPIQSAVANNI 465
Cdd:PRK09695 407 AETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMFPFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQI 486
                        490       500       510       520       530       540
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518298651 466 GTSGALLVSANTVGGVAAKLISPQSIAIATASVQQVGKESELLKMTLRYSFAFIIFICLWTFMLNFI 532
Cdd:PRK09695 487 NVSDTLLVAANTSGGVTGKMISPQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGIITLLQAYV 553
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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