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Conserved domains on  [gi|518573483|ref|WP_019743690|]
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MULTISPECIES: GntR family transcriptional regulator [Bacillus]

Protein Classification

GntR family transcriptional regulator( domain architecture ID 11448193)

GntR family transcriptional regulator simlar to MngR, which is involved in the regulation of mannosyl-glycerate transport and metabolism

CATH:  1.10.10.10
Gene Ontology:  GO:0003677|GO:0003700
PubMed:  33509775|26172911|2060763

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
2-115 3.80e-45

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


:

Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 142.63  E-value: 3.80e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   2 IQIDPRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTEGAQL 81
Cdd:COG1725    1 IRIDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARE 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 518573483  82 KLNEGKVLEMKEQLRQLIIEAHYAGIDIHQLKEW 115
Cdd:COG1725   81 LLEERREEFLEEALRELVAEARRLGLSLEELLEL 114
 
Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
2-115 3.80e-45

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 142.63  E-value: 3.80e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   2 IQIDPRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTEGAQL 81
Cdd:COG1725    1 IRIDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARE 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 518573483  82 KLNEGKVLEMKEQLRQLIIEAHYAGIDIHQLKEW 115
Cdd:COG1725   81 LLEERREEFLEEALRELVAEARRLGLSLEELLEL 114
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 11-76 6.10e-21

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 79.80  E-value: 6.10e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 518573483  11 PIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVT 76
Cdd:cd07377    1 PLYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 13-75 6.94e-16

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 66.87  E-value: 6.94e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 518573483   13 YEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:pfam00392   2 YEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
16-75 1.75e-14

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 62.98  E-value: 1.75e-14
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483    16 IIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
 4-77 6.04e-12

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 61.22  E-value: 6.04e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 518573483   4 IDPRSAAPIYEQIieqlKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE 77
Cdd:PRK15481   2 ITGKTANEIFDSI----RQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIRG 71
C_P_lyase_phnF TIGR02325
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ...
 4-75 1.36e-07

phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]


Pssm-ID: 131378 [Multi-domain]  Cd Length: 238  Bit Score: 48.24  E-value: 1.36e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518573483    4 IDPRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:TIGR02325   1 IERTSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFV 72
 
Name Accession Description Interval E-value
YhcF COG1725
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
2-115 3.80e-45

DNA-binding transcriptional regulator YhcF, GntR family [Transcription];


Pssm-ID: 441331 [Multi-domain]  Cd Length: 114  Bit Score: 142.63  E-value: 3.80e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   2 IQIDPRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTEGAQL 81
Cdd:COG1725    1 IRIDFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAEDARE 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 518573483  82 KLNEGKVLEMKEQLRQLIIEAHYAGIDIHQLKEW 115
Cdd:COG1725   81 LLEERREEFLEEALRELVAEARRLGLSLEELLEL 114
ARO8 COG1167
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ...
 1-104 7.14e-26

DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis


Pssm-ID: 440781 [Multi-domain]  Cd Length: 471  Bit Score: 100.67  E-value: 7.14e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   1 MIQIDPRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTEGAQ 80
Cdd:COG1167    2 LIRLDRDSSGPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAARLP 81

                         90       100
                 ....*....|....*....|....*.
gi 518573483  81 LKLNEGKVLEMKEQ--LRQLIIEAHY 104
Cdd:COG1167   82 APAPAPRAAAAVAApaLRRLLEAAPG 107
WHTH_GntR cd07377
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ...
 11-76 6.10e-21

Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.


Pssm-ID: 153418 [Multi-domain]  Cd Length: 66  Bit Score: 79.80  E-value: 6.10e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 518573483  11 PIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVT 76
Cdd:cd07377    1 PLYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
MngR COG2188
DNA-binding transcriptional regulator, GntR family [Transcription];
7-77 1.68e-16

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441791 [Multi-domain]  Cd Length: 238  Bit Score: 72.59  E-value: 1.68e-16
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 518573483   7 RSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE 77
Cdd:COG2188    1 SSPVPLYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAE 71
GntR pfam00392
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ...
 13-75 6.94e-16

Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.


Pssm-ID: 306822 [Multi-domain]  Cd Length: 64  Bit Score: 66.87  E-value: 6.94e-16
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 518573483   13 YEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:pfam00392   2 YEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
HTH_GNTR smart00345
helix_turn_helix gluconate operon transcriptional repressor;
16-75 1.75e-14

helix_turn_helix gluconate operon transcriptional repressor;


Pssm-ID: 197669 [Multi-domain]  Cd Length: 60  Bit Score: 62.98  E-value: 1.75e-14
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483    16 IIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:smart00345   1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
FadR COG2186
DNA-binding transcriptional regulator, FadR family [Transcription];
6-119 3.80e-14

DNA-binding transcriptional regulator, FadR family [Transcription];


Pssm-ID: 441789 [Multi-domain]  Cd Length: 232  Bit Score: 66.11  E-value: 3.80e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   6 PRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE-------- 77
Cdd:COG2186    2 PIRRRSLAEQVAEQLRELILSGELKPGDRLPSERELAEQLGVSRTTVREALRALEALGLVEVRQGGGTFVREpspwalld 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 518573483  78 --GAQLKLNEGKVLEMKEqLRQlIIEAHYAGI--------DIHQLKEWLEEI 119
Cdd:COG2186   82 plALLLALDDASLRDLLE-ARL-ALEPEAARLaaeratdeDLARLEAALAEM 131
PRK15481 PRK15481
transcriptional regulatory protein PtsJ; Provisional
 4-77 6.04e-12

transcriptional regulatory protein PtsJ; Provisional


Pssm-ID: 185378 [Multi-domain]  Cd Length: 431  Bit Score: 61.22  E-value: 6.04e-12
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 518573483   4 IDPRSAAPIYEQIieqlKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE 77
Cdd:PRK15481   2 ITGKTANEIFDSI----RQLIQAGRLRPGDSLPPVRELASELGVNRNTVAAAYKRLVTAGLAQSQGRNGTVIRG 71
PRK09764 PRK09764
GntR family transcriptional regulator;
8-77 4.49e-09

GntR family transcriptional regulator;


Pssm-ID: 182065 [Multi-domain]  Cd Length: 240  Bit Score: 52.52  E-value: 4.49e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   8 SAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE 77
Cdd:PRK09764   2 GHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKE 71
PRK14999 PRK14999
histidine utilization repressor; Provisional
 1-77 2.36e-08

histidine utilization repressor; Provisional


Pssm-ID: 184961 [Multi-domain]  Cd Length: 241  Bit Score: 50.32  E-value: 2.36e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 518573483   1 MIQIDPRSA-APIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE 77
Cdd:PRK14999   1 MYSSRSRSApAPFYETVKQDICKKIAGGVWQPHDRIPSEAELVAQYGFSRMTINRALRELTDEGWLVRLQGVGTFVAE 78
PRK10225 PRK10225
Uxu operon transcriptional regulator;
5-128 1.28e-07

Uxu operon transcriptional regulator;


Pssm-ID: 182318 [Multi-domain]  Cd Length: 257  Bit Score: 48.48  E-value: 1.28e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   5 DPRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV--------T 76
Cdd:PRK10225   3 SATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVldssgshnT 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 518573483  77 EGAQLKL-NEGKVLEMKeQLRQLIIE--AHYAGI-----DIHQLKEWLE----EIGSSLKGGKQ 128
Cdd:PRK10225  83 DSPDANVcNDAGPFELL-QARQLLESniAEFAALqatreDIVKMRQALQleerELASSAPGSSE 145
C_P_lyase_phnF TIGR02325
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ...
 4-75 1.36e-07

phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]


Pssm-ID: 131378 [Multi-domain]  Cd Length: 238  Bit Score: 48.24  E-value: 1.36e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518573483    4 IDPRSAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:TIGR02325   1 IERTSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFV 72
PRK10421 PRK10421
DNA-binding transcriptional repressor LldR; Provisional
 11-75 1.78e-07

DNA-binding transcriptional repressor LldR; Provisional


Pssm-ID: 236690 [Multi-domain]  Cd Length: 253  Bit Score: 48.22  E-value: 1.78e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 518573483  11 PIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:PRK10421   2 RLSDEVADRVRALIEEKNLEAGMKLPAERQLAMQLGVSRNSLREALAKLVSEGVLLSRRGGGTFI 66
PRK11402 PRK11402
transcriptional regulator PhoB;
8-75 3.44e-06

transcriptional regulator PhoB;


Pssm-ID: 183118 [Multi-domain]  Cd Length: 241  Bit Score: 44.44  E-value: 3.44e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 518573483   8 SAAPIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:PRK11402   6 SHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFV 73
GntR COG1802
DNA-binding transcriptional regulator, GntR family [Transcription];
1-77 3.99e-06

DNA-binding transcriptional regulator, GntR family [Transcription];


Pssm-ID: 441407 [Multi-domain]  Cd Length: 222  Bit Score: 44.14  E-value: 3.99e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518573483   1 MIQIDPRSAAPIYEQIIEQLKILCLKGVMKPGDKLpSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE 77
Cdd:COG1802    1 MTSPSPLRRESLAEQVYEALREAILSGELPPGERL-SEAELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAP 76
PRK09990 PRK09990
DNA-binding transcriptional regulator GlcC; Provisional
 11-75 4.39e-06

DNA-binding transcriptional regulator GlcC; Provisional


Pssm-ID: 182186 [Multi-domain]  Cd Length: 251  Bit Score: 43.99  E-value: 4.39e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 518573483  11 PIYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:PRK09990   7 PIADVVAERIERLIVDGVLKVGQALPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRGSFV 71
pdhR PRK09464
pyruvate dehydrogenase complex transcriptional repressor PdhR;
16-77 2.96e-05

pyruvate dehydrogenase complex transcriptional repressor PdhR;


Pssm-ID: 181879 [Multi-domain]  Cd Length: 254  Bit Score: 41.93  E-value: 2.96e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 518573483  16 IIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYVTE 77
Cdd:PRK09464  15 IEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQS 76
PRK10079 PRK10079
phosphonate metabolism transcriptional regulator PhnF; Provisional
 6-75 1.30e-03

phosphonate metabolism transcriptional regulator PhnF; Provisional


Pssm-ID: 182227 [Multi-domain]  Cd Length: 241  Bit Score: 37.06  E-value: 1.30e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518573483   6 PRSAAPIYEQIIEQLKILcLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:PRK10079   7 PTSYPTRYQEIAAKLEQE-LRQHYRCGDYLPAEQQLAARYEVNRHTLRRAIDQLVEKGWVQRRQGVGVLV 75
Rrf2 pfam02082
Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur ...
 29-72 2.69e-03

Iron-dependent Transcriptional regulator; Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription regulation. The iron binding is mediated by three conserved cysteine residues. Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 396591 [Multi-domain]  Cd Length: 131  Bit Score: 35.22  E-value: 2.69e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 518573483   29 MKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRG 72
Cdd:pfam02082  17 LHPGGEPVTSEEIAERQNISPVYLEKILAKLRKAGLVESVRGAG 60
PRK11523 PRK11523
transcriptional regulator ExuR;
12-75 3.63e-03

transcriptional regulator ExuR;


Pssm-ID: 183176 [Multi-domain]  Cd Length: 253  Bit Score: 35.59  E-value: 3.63e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 518573483  12 IYEQIIEQLKILCLKGVMKPGDKLPSVRELATIIIANPNTVSKAYKELEREGIIETLRGRGTYV 75
Cdd:PRK11523   9 LYQQLAAELKERIEQGVYLVGDKLPAERFIADEKNVSRTVVREAIIMLEVEGYVEVRKGSGIHV 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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