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Conserved domains on  [gi|518783285|ref|WP_019940574|]
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class II fructose-bisphosphate aldolase [Dyadobacter beijingensis]

Protein Classification

class II fructose-bisphosphate aldolase( domain architecture ID 10013149)

class II fructose-1,6-bisphosphate (FBP) aldolase catalyzes the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate

EC:  4.1.2.13
Gene Ontology:  GO:0008270|GO:0004332|GO:0016832

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 10-358 0e+00

fructose-bisphosphate aldolase; Provisional


:

Pssm-ID: 236406  Cd Length: 350  Bit Score: 675.74  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  10 PGVVTGDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQAAIAGGISG 89
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  90 AQHVHQMAALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGM 169
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 170 TLEIELGVTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYIK 249
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 250 QKFGTGDLPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKYYD 329
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*....
gi 518783285 330 PRVWLRKGEESMISRLKVAFEDLNCINQL 358
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGVL 349
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 10-358 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 675.74  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  10 PGVVTGDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQAAIAGGISG 89
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  90 AQHVHQMAALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGM 169
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 170 TLEIELGVTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYIK 249
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 250 QKFGTGDLPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKYYD 329
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*....
gi 518783285 330 PRVWLRKGEESMISRLKVAFEDLNCINQL 358
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGVL 349
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 15-358 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 619.77  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  15 GDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQAAIAGGISGAQHVH 94
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  95 QMAALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIE 174
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 175 LGVTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYIKQKFGT 254
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKISPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 255 GD-LPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKYYDPRVW 333
Cdd:cd00946  241 ADdKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|....*
gi 518783285 334 LRKGEESMISRLKVAFEDLNCINQL 358
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNSVNKL 345
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 10-358 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 558.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   10 PGVVTGDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQA-AIAGGIS 88
Cdd:TIGR01520   7 PGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGaSILGAIA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   89 GAQHVHQMAALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLG 168
Cdd:TIGR01520  87 GAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLKRMAKIK 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  169 MTLEIELGVTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYI 248
Cdd:TIGR01520 167 MWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKISPNFSIAAAFGNVHGVYKPGNVKLTPDILADGQEYV 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  249 KQKFGTGDL-PVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKY 327
Cdd:TIGR01520 247 SEKLGLPAAkPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPDKPNKKF 326

                         330       340       350
                  ....*....|....*....|....*....|.
gi 518783285  328 YDPRVWLRKGEESMISRLKVAFEDLNCINQL 358
Cdd:TIGR01520 327 YDPRVWLREGEKSMKARVEKACQELNNINVL 357
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
20-357 4.07e-108

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 317.43  E-value: 4.07e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGkslsnanqqaaiaGGISGAQHVHQMAAL 99
Cdd:pfam01116   5 ELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAG-------------GAEALAALVRAAAEA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  100 YEVPVILHTDHCAKkllpwIDGLLDAGERYFdqygkplySSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:pfam01116  72 AGVPVALHLDHGAS-----FELIKEAIEAGF--------TSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIG 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  180 GEEDGVdnsdVDSSKLYTQPEEVAFAYEELSkispNFTIAAAFGNVHGVYKPGNvKLEPKILRNSQDYIkqkfgtgdlPV 259
Cdd:pfam01116 139 GEEDGV----VVDEKLYTDPEEAAEFVEATG----VDALAVAIGNVHGVYKPGP-KLDFDRLKEIQEAV---------PV 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  260 NFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKegylqsqlgnpegadspnkkyyDPRVWLRKGEE 339
Cdd:pfam01116 201 PLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPNK----------------------DPRKYLRPAEE 258

                         330
                  ....*....|....*...
gi 518783285  340 SMISRLKVAFEDLNCINQ 357
Cdd:pfam01116 259 AMKEVVKEKIRLFGSAGK 276
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 20-357 1.26e-107

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 316.26  E-value: 1.26e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFyagkslsnanqqaaiAGGISGAQHVHQMAAL 99
Cdd:COG0191    7 ELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKY---------------AGLEYLAAMVRAAAEE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHCAkkllpwidglldaGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:COG0191   72 ASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 180 GEEDGVDNSDVDssKLYTQPEEVAFAYEElskiSPNFTIAAAFGNVHGVYKpGNVKLEPKILRNSQDYIkqkfgtgdlPV 259
Cdd:COG0191  139 GEEDGVDVDDAE--ALYTDPEEAAEFVEE----TGVDALAVAIGTVHGVYK-GEPKLDFDRLKEIREAV---------PV 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 260 NFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKegylqsqlgnpegadsPNKkyYDPRVWLRKGEE 339
Cdd:COG0191  203 PLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAEN----------------PDK--YDPRKYLKPARE 264

                        330
                 ....*....|....*...
gi 518783285 340 SMISRLKVAFEDLNCINQ 357
Cdd:COG0191  265 AMKEVVKEKIRLFGSAGK 282
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 10-358 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 675.74  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  10 PGVVTGDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQAAIAGGISG 89
Cdd:PRK09197   1 PGVATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  90 AQHVHQMAALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGM 169
Cdd:PRK09197  81 AKHVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGM 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 170 TLEIELGVTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYIK 249
Cdd:PRK09197 161 TLEIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVS 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 250 QKFGTGDLPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKYYD 329
Cdd:PRK09197 241 KKFGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYD 320

                        330       340
                 ....*....|....*....|....*....
gi 518783285 330 PRVWLRKGEESMISRLKVAFEDLNCINQL 358
Cdd:PRK09197 321 PRVWLRAAEASMAARLEEAFEDLNSIGVL 349
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 15-358 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 619.77  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  15 GDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQAAIAGGISGAQHVH 94
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  95 QMAALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIE 174
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 175 LGVTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYIKQKFGT 254
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKISPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 255 GD-LPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKYYDPRVW 333
Cdd:cd00946  241 ADdKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|....*
gi 518783285 334 LRKGEESMISRLKVAFEDLNCINQL 358
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNSVNKL 345
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 10-358 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 558.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   10 PGVVTGDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQA-AIAGGIS 88
Cdd:TIGR01520   7 PGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGaSILGAIA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   89 GAQHVHQMAALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLG 168
Cdd:TIGR01520  87 GAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLKRMAKIK 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  169 MTLEIELGVTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYI 248
Cdd:TIGR01520 167 MWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKISPNFSIAAAFGNVHGVYKPGNVKLTPDILADGQEYV 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  249 KQKFGTGDL-PVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKY 327
Cdd:TIGR01520 247 SEKLGLPAAkPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPDKPNKKF 326

                         330       340       350
                  ....*....|....*....|....*....|.
gi 518783285  328 YDPRVWLRKGEESMISRLKVAFEDLNCINQL 358
Cdd:TIGR01520 327 YDPRVWLREGEKSMKARVEKACQELNNINVL 357
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 18-356 1.09e-160

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 453.49  E-value: 1.09e-160
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  18 VSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSL-SNANQQAAIAGGISGAQHVHQM 96
Cdd:cd00453    1 VQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVkSDVPQGAAILGAISGAHHVHQM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  97 AALYEVPVILHTDHCAKKLLPWIDGLLDAGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELG 176
Cdd:cd00453   81 AEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 177 VTGGEEDGVDNSDVDSSKLYTQPEEVAFAYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYIKQKFGTGD 256
Cdd:cd00453  161 CTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFTIAASFGNVHGVYKKGNVVLTPTILRDSQEYVSKKHNLPH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 257 LPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGYLQSQLGNPEGADSPNKKYYDPRVWLRK 336
Cdd:cd00453  241 NSLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVWLRA 320

                        330       340
                 ....*....|....*....|
gi 518783285 337 GEESMISRLKVAFEDLNCIN 356
Cdd:cd00453  321 GQTSMIARLEKAFQELNAID 340
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 13-358 6.37e-125

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 360.48  E-value: 6.37e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   13 VTGDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKslsnanqqaaiaGGISGAQH 92
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAGL------------GAISAMVK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   93 VHQMAALYEVPVILHTDHCAkkllpwidglldaGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLE 172
Cdd:TIGR00167  69 AMSEAYPYGVPVALHLDHGA-------------SEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVE 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  173 IELGVTGGEEDGVdnSDVDSSKLYTQPEEvafaYEELSKISPNFTIAAAFGNVHGVYKPGNVKLEPKILRNSQDYIKqkf 252
Cdd:TIGR00167 136 AELGTLGGEEDGV--SVADESALYTDPEE----AKEFVKLTGVDSLAAAIGNVHGVYKGEPKGLDFERLEEIQKYVN--- 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  253 gtgdlpVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAkegylqsqlgnpegadspNKKYYDPRV 332
Cdd:TIGR00167 207 ------LPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQIAFAAAVRNYYAE------------------NKDYYDPRV 262

                         330       340
                  ....*....|....*....|....*.
gi 518783285  333 WLRKGEESMISRLKVAFEDLNCINQL 358
Cdd:TIGR00167 263 WLRPGEKAMKEVVLEKIKLFGSANKA 288
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
20-357 4.07e-108

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 317.43  E-value: 4.07e-108
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGkslsnanqqaaiaGGISGAQHVHQMAAL 99
Cdd:pfam01116   5 ELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAG-------------GAEALAALVRAAAEA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  100 YEVPVILHTDHCAKkllpwIDGLLDAGERYFdqygkplySSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:pfam01116  72 AGVPVALHLDHGAS-----FELIKEAIEAGF--------TSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIG 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  180 GEEDGVdnsdVDSSKLYTQPEEVAFAYEELSkispNFTIAAAFGNVHGVYKPGNvKLEPKILRNSQDYIkqkfgtgdlPV 259
Cdd:pfam01116 139 GEEDGV----VVDEKLYTDPEEAAEFVEATG----VDALAVAIGNVHGVYKPGP-KLDFDRLKEIQEAV---------PV 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  260 NFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKegylqsqlgnpegadspnkkyyDPRVWLRKGEE 339
Cdd:pfam01116 201 PLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPNK----------------------DPRKYLRPAEE 258

                         330
                  ....*....|....*...
gi 518783285  340 SMISRLKVAFEDLNCINQ 357
Cdd:pfam01116 259 AMKEVVKEKIRLFGSAGK 276
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 20-357 1.26e-107

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 316.26  E-value: 1.26e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFyagkslsnanqqaaiAGGISGAQHVHQMAAL 99
Cdd:COG0191    7 ELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKY---------------AGLEYLAAMVRAAAEE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHCAkkllpwidglldaGERYFDQYGKPLYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:COG0191   72 ASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 180 GEEDGVDNSDVDssKLYTQPEEVAFAYEElskiSPNFTIAAAFGNVHGVYKpGNVKLEPKILRNSQDYIkqkfgtgdlPV 259
Cdd:COG0191  139 GEEDGVDVDDAE--ALYTDPEEAAEFVEE----TGVDALAVAIGTVHGVYK-GEPKLDFDRLKEIREAV---------PV 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 260 NFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKegylqsqlgnpegadsPNKkyYDPRVWLRKGEE 339
Cdd:COG0191  203 PLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAEN----------------PDK--YDPRKYLKPARE 264

                        330
                 ....*....|....*...
gi 518783285 340 SMISRLKVAFEDLNCINQ 357
Cdd:COG0191  265 AMKEVVKEKIRLFGSAGK 282
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 20-356 2.69e-47

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 161.54  E-value: 2.69e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGgAIFYAGKSLSnanqqaaiaggisgAQHVHQMAAL 99
Cdd:cd00947    3 ELLKKAREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEG-AIKYAGLELL--------------VAMVKAAAER 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHCAKklLPWIDGLLDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:cd00947   68 ASVPVALHLDHGSS--FELIKRAIRAG-----------FSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIG 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 180 GEEDGVdnsdVDSSKLYTQPEEVA-FAyeELSKISpnfTIAAAFGNVHGVYKPGNVKLEPKILRNsqdyIKQKfgtgdLP 258
Cdd:cd00947  135 GEEDGV----VGDEGLLTDPEEAEeFV--EETGVD---ALAVAIGTSHGAYKGGEPKLDFDRLKE----IAER-----VN 196

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 259 VNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQwstwegvLNYYKAKEGYLQSqlgnpegadspNKKYYDPRVWLRKGE 338
Cdd:cd00947  197 VPLVLHGGSGIPDEQIRKAIKLGVCKININTDLR-------LAFTAALREYLAE-----------NPKEFDPRKYLAPAI 258

                        330
                 ....*....|....*...
gi 518783285 339 ESMISRLKVAFEDLNCIN 356
Cdd:cd00947  259 EAVKEVVKHKMELFGSAG 276
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 20-358 1.01e-31

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 120.62  E-value: 1.01e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQfSNGGAIFYAGKSLSNANQQAAiaggisgaqhvhqmAAL 99
Cdd:PRK09195   8 QMLNNAQRGGYAVPAFNIHNLETMQVVVETAAELHSPVIIA-GTPGTFSYAGTEYLLAIVSAA--------------AKQ 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHCAKklLPWIDGLLDAGERyfdqygkplysSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:PRK09195  73 YHHPLALHLDHHEK--FDDIAQKVRSGVR-----------SVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAELGRLG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 180 GEEDGVDNSDVDSskLYTQPEEvAFAYEELSKISpnfTIAAAFGNVHGVYKPgnvklEPKILRNSQDYIKQKFgtgDLPV 259
Cdd:PRK09195 140 GQEDDLQVDEADA--LYTDPAQ-AREFVEATGID---SLAVAIGTAHGMYKG-----EPKLDFDRLENIRQWV---NIPL 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 260 nfVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYkakegylqsqLGNPEGAdspnkkyyDPRVWLRKGEE 339
Cdd:PRK09195 206 --VLHGASGLPTKDIQQTIKLGICKVNVATELKIAFSQALKNYL----------TEHPEAN--------DPRHYLQPAKS 265

                        330
                 ....*....|....*....
gi 518783285 340 SMISRLKVAFEDLNCINQL 358
Cdd:PRK09195 266 AMKDVVSKVIADCGCEGKA 284
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
18-292 6.33e-30

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 115.98  E-value: 6.33e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  18 VSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNgGAIFYAGKSlsnanqqaAIAGgisgaqHVHQMA 97
Cdd:PRK12857   6 VAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQASQ-GAIKYAGIE--------YISA------MVRTAA 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  98 ALYEVPVILHTDHCAKkllpwidglldageryFDQYGKPL---YSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIE 174
Cdd:PRK12857  71 EKASVPVALHLDHGTD----------------FEQVMKCIrngFTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEAE 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 175 LGVTGGEEDGVDNSDVDSskLYTQPEEVAFAYEELSKISpnftIAAAFGNVHGVYkpgnvKLEPKILRNSQDYIKQKfgt 254
Cdd:PRK12857 135 LGKIGGTEDDITVDEREA--AMTDPEEARRFVEETGVDA----LAIAIGTAHGPY-----KGEPKLDFDRLAKIKEL--- 200

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 518783285 255 gdLPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQ 292
Cdd:PRK12857 201 --VNIPIVLHGSSGVPDEAIRKAISLGVRKVNIDTNIR 236
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
20-341 2.54e-27

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 109.01  E-value: 2.54e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQfSNGGAIFYAGKSLSNANQQAAiaggisgaqhvhqmAAL 99
Cdd:PRK12737   8 NMLKKAQAEGYAVPAFNIHNLETLQVVVETAAELRSPVILA-GTPGTFSYAGTDYIVAIAEVA--------------ARK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHcaKKLLPWIDGLLDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:PRK12737  73 YNIPLALHLDH--HEDLDDIKKKVRAG-----------IRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 180 GEEDGVDNSDVDSskLYTQPEEvAFAYEELSKISpnfTIAAAFGNVHGVYKPgnvklEPKILRNSQDYIKQKFgtgDLPV 259
Cdd:PRK12737 140 GQEDDLVVDEKDA--MYTNPDA-AAEFVERTGID---SLAVAIGTAHGLYKG-----EPKLDFERLAEIREKV---SIPL 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 260 nfVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAkegylqsqlgNPEGAdspnkkyyDPRVWLRKGEE 339
Cdd:PRK12737 206 --VLHGASGVPDEDVKKAISLGICKVNVATELKIAFSDAVKKYFYE----------NPKAN--------DPRKYMTPGKA 265


                 ..
gi 518783285 340 SM 341
Cdd:PRK12737 266 AM 267
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 18-357 1.81e-25

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 103.91  E-value: 1.81e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  18 VSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSlsnanqqaAIAGGISGAQHVHQMA 97
Cdd:PRK08610   6 MKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFY--------TVVKMVEGLMHDLNIT 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  98 alyeVPVILHTDH------CAKKLlpwidgllDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTL 171
Cdd:PRK08610  78 ----IPVAIHLDHgssfekCKEAI--------DAG-----------FTSVMIDASHSPFEENVATTKKVVEYAHEKGVSV 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 172 EIELGVTGGEEDGVdnsdVDSSKLYTQPEEVafayEELSKISPNFTIAAAFGNVHGVYKPgnvklEPKILRNSQDYIKQK 251
Cdd:PRK08610 135 EAELGTVGGQEDDV----VADGIIYADPKEC----QELVEKTGIDALAPALGSVHGPYKG-----EPKLGFKEMEEIGLS 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 252 FGtgdLPVnfVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVlnyykakegylQSQLGNpegadspNKKYYDPR 331
Cdd:PRK08610 202 TG---LPL--VLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAV-----------RDVLNN-------DKEVYDPR 258

                        330       340
                 ....*....|....*....|....*.
gi 518783285 332 VWLRKGEESMISRLKVAFEDLNCINQ 357
Cdd:PRK08610 259 KYLGPAREAIKETVKGKIKEFGTSNR 284
PRK08185 PRK08185
hypothetical protein; Provisional
 20-331 5.47e-25

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 102.50  E-value: 5.47e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFsnggaifyagkslsNANQQAAIagGISGAQHVHQMAAL 99
Cdd:PRK08185   3 ELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAI--------------HPNELDFL--GDNFFAYVRERAKR 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHCAKkllpwIDGLLDAgeryfDQYGkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:PRK08185  67 SPVPFVIHLDHGAT-----IEDVMRA-----IRCG---FTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELGTIG 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 180 GE----EDGVDnsdvdsSKLYTQPEEvAFAYEELSKISpnfTIAAAFGNVHGVYKPGnvkLEPKILRNSQDYIKQKFgtg 255
Cdd:PRK08185 134 NTgtsiEGGVS------EIIYTDPEQ-AEDFVSRTGVD---TLAVAIGTAHGIYPKD---KKPELQMDLLKEINERV--- 197

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 518783285 256 DLPvnFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWStwegvlnYYKAKEGYLQSqlgNPEGADsPNKKYYDPR 331
Cdd:PRK08185 198 DIP--LVLHGGSANPDAEIAESVQLGVGKINISSDMKYA-------FFKKVREILSD---NPSLYE-PNQIYPSAI 260
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
24-291 3.74e-24

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 100.21  E-value: 3.74e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  24 HANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNggaIFYAGKSLSnanqqaaiaggiSGAQHVHQMAALYEVP 103
Cdd:PRK06801  12 HARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINIAE---VHFKYISLE------------SLVEAVKFEAARHDIP 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 104 VILHTDHcakkllpwidGLldagerYFDQYGKPL---YSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTGG 180
Cdd:PRK06801  77 VVLNLDH----------GL------HFEAVVRALrlgFSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELGAVGG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 181 EEDGVDNSDVDSSKlYTQPEEvAFAYEELSKISpnfTIAAAFGNVHGVYKPgnvklEPKILRNSQDYIKQKFGtgdlpVN 260
Cdd:PRK06801 141 DEGGALYGEADSAK-FTDPQL-ARDFVDRTGID---ALAVAIGNAHGKYKG-----EPKLDFARLAAIHQQTG-----LP 205

                        250       260       270
                 ....*....|....*....|....*....|.
gi 518783285 261 FVFHGGSGSSREEIREAIEYGAIKMNIDTDM 291
Cdd:PRK06801 206 LVLHGGSGISDADFRRAIELGIHKINFYTGM 236
PRK06806 PRK06806
class II aldolase;
20-309 2.03e-22

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 95.21  E-value: 2.03e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFS----NGGAIFYAGKSLSNANQQAaiaggisgaqhvhq 95
Cdd:PRK06806   8 ELLKKANQENYGVGAFSVANMEMVMGAIKAAEELNSPIILQIAevrlNHSPLHLIGPLMVAAAKQA-------------- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  96 maalyEVPVILHTDHcaKKLLPWIDGLLDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIEL 175
Cdd:PRK06806  74 -----KVPVAVHFDH--GMTFEKIKEALEIG-----------FTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEI 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 176 GVTGGEEDGVDnsdvDSSKLYTQPEEVAFAYEElSKISpnfTIAAAFGNVHGVYKpGNVKLEPKILRNSQDyikqkfgtg 255
Cdd:PRK06806 136 GRVGGSEDGSE----DIEMLLTSTTEAKRFAEE-TDVD---ALAVAIGNAHGMYN-GDPNLRFDRLQEIND--------- 197

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 518783285 256 DLPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAKEGY 309
Cdd:PRK06806 198 VVHIPLVLHGGSGISPEDFKKCIQHGIRKINVATATFNSVITAVNNLVLNTPYS 251
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 18-341 1.21e-21

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 93.19  E-value: 1.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  18 VSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAG-KSLsnanqqaaiaggisgaqhVHQM 96
Cdd:PRK07709   6 MKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGfKTV------------------VAMV 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  97 AALYE-----VPVILHTDHCAKklLPWIDGLLDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTL 171
Cdd:PRK07709  68 KALIEemnitVPVAIHLDHGSS--FEKCKEAIDAG-----------FTSVMIDASHHPFEENVETTKKVVEYAHARNVSV 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 172 EIELGVTGGEEDGVdnsdVDSSKLYTQPEEVafayEELSKISPNFTIAAAFGNVHGVYKPgnvklEPKILRNSQDYIKQK 251
Cdd:PRK07709 135 EAELGTVGGQEDDV----IAEGVIYADPAEC----KHLVEATGIDCLAPALGSVHGPYKG-----EPNLGFAEMEQVRDF 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 252 FGtgdlpVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQwstwegvLNYYKAKEGYLqsqlgnpegadSPNKKYYDPR 331
Cdd:PRK07709 202 TG-----VPLVLHGGTGIPTADIEKAISLGTSKINVNTENQ-------IEFTKAVREVL-----------NKDQEVYDPR 258

                        330
                 ....*....|
gi 518783285 332 VWLRKGEESM 341
Cdd:PRK07709 259 KFIGPGRDAI 268
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
24-357 6.05e-20

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 89.63  E-value: 6.05e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  24 HANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSnGGAIFYAGKSLSNanqqaaiaggisgaqhvHQMAALYE-- 101
Cdd:PRK09196  12 HAAEHGYGVPAFNVNNLEQVQAIMEAADETDSPVILQAS-AGARKYAGEPFLR-----------------HLILAAVEey 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 102 --VPVILHTDH------CAKKLlpwidglldageryfdQYGkplYSSHMLDLSEEPIEENIeicAKY---------FERM 164
Cdd:PRK09196  74 phIPVVMHQDHgnspatCQRAI----------------QLG---FTSVMMDGSLKADGKTP---ASYeynvdvtrkVVEM 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 165 A-KLGMTLEIELGV-------TGGEEDGVDNSDV-DSSKLYTQPEEvAFAYEELSKISpnfTIAAAFGNVHGVYKpGNVK 235
Cdd:PRK09196 132 AhACGVSVEGELGClgsletgMGGEEDGHGAEGKlSHDQLLTDPEE-AADFVKKTQVD---ALAIAIGTSHGAYK-FTRK 206

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 236 LEPKILRNSQ-DYIKQKfgtgdLP-VNFVFHGGS---------------------GSSREEIREAIEYGAIKMNIDTDMQ 292
Cdd:PRK09196 207 PTGDVLAIDRiKEIHAR-----LPnTHLVMHGSSsvpqelldiineyggdmpetyGVPVEEIQEGIKHGVRKVNIDTDLR 281

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 518783285 293 W-STweGVLNYYKAKegylqsqlgnpegadspNKKYYDPRVWLRKGEESMISRLKVAFEDLNCINQ 357
Cdd:PRK09196 282 LaMT--GAIRRFLAE-----------------NPSEFDPRKYLKPAMEAMKKICKARYEAFGTAGQ 328
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
20-346 9.49e-19

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 85.55  E-value: 9.49e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSnGGAIFYAGKSLSNANQQAAIAggisgaqHVHQMAal 99
Cdd:PRK07084  14 EMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVS-KGARKYANATLLRYMAQGAVE-------YAKELG-- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHCakkllpwidgllDAGERYFD--QYGkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGV 177
Cdd:PRK07084  84 CPIPIVLHLDHG------------DSFELCKDciDSG---FSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGV 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 178 TGGEEDGVdnsdVDSSKLYTQPEEVafayEELSKISPNFTIAAAFGNVHGVYK--PGnvKLEPKILRNSQDYIKQKF--- 252
Cdd:PRK07084 149 LAGVEDEV----SAEHHTYTQPEEV----EDFVKKTGVDSLAISIGTSHGAYKfkPG--QCPPPLRFDILEEIEKRIpgf 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 253 -----GTGDLPVNFVF----HGGS-----GSSREEIREAIEYGAIKMNIDTDmqwstweGVLNYYKAKEGYLqsqlgnpe 318
Cdd:PRK07084 219 pivlhGSSSVPQEYVKtineYGGKlkdaiGIPEEQLRKAAKSAVCKINIDSD-------GRLAMTAAIRKVF-------- 283

                        330       340
                 ....*....|....*....|....*...
gi 518783285 319 gADSPnkKYYDPRVWLRKGEESMISRLK 346
Cdd:PRK07084 284 -DEKP--EEFDPRKYLGPARDELKKLYK 308
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
24-357 4.18e-18

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 84.06  E-value: 4.18e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  24 HANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSnGGAIFYAGKSLSNanqqaaiaggisgaqhvHQMAALYE-- 101
Cdd:PRK13399  12 HAAENGYGVPAFNVNNMEQILAIMEAAEATDSPVILQAS-RGARKYAGDAMLR-----------------HMVLAAAEmy 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 102 --VPVILHTDHcakkllpwidgllDAGERYFDQYGKPLYSSHMLDLSEEPIEENIE------ICAKYFERMAKL-GMTLE 172
Cdd:PRK13399  74 pdIPICLHQDH-------------GNSPATCQSAIRSGFTSVMMDGSLLADGKTPAsydynvDVTRRVTEMAHAvGVSVE 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 173 IELGV-------TGGEEDGVD-NSDVDSSKLYTQPEEvAFAYEELSKISpnfTIAAAFGNVHGVYKpgnVKLEP--KILr 242
Cdd:PRK13399 141 GELGClgsletgEAGEEDGVGaEGKLSHDQMLTDPDQ-AVDFVQRTGVD---ALAIAIGTSHGAYK---FTRKPdgDIL- 212

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 243 nSQDYIKQKFGTgdLP-VNFVFHGGS---------------------GSSREEIREAIEYGAIKMNIDTDMQWstwegvl 300
Cdd:PRK13399 213 -AIDRIEEIHAR--LPnTHLVMHGSSsvpqelqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRL------- 282

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 518783285 301 nyykAKEGYLQSQLgnpegADSPNKkyYDPRVWLRKGEESMISRLKVAFEDLNCINQ 357
Cdd:PRK13399 283 ----AMTGAIRKVL-----AEHPSE--FDPRKALKPAMKAMTALCKQRFEAFGTAGQ 328
PLN02858 PLN02858
fructose-bisphosphate aldolase
 1-299 5.24e-18

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 85.67  E-value: 5.24e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285    1 MSETTKRFApgVVTGDGVSEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGgaifyagkslsnanqq 80
Cdd:PLN02858 1087 LAEVVKSWA--RPARSSTKELLLNAEKGGYAVGAFNVYNLEGIEAVVAAAEAEKSPAILQVHPG---------------- 1148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285   81 AAIAGGISGAQHVHQMAALYEVPVILHTDHCAKKllpwiDGLLDAGERYFDqygkplysSHMLDLSEEPIEENIEicakY 160
Cdd:PLN02858 1149 ALKQGGIPLVSCCIAAAEQASVPITVHFDHGTSK-----HELLEALELGFD--------SVMVDGSHLSFTENIS----Y 1211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  161 FERMAKL----GMTLEIELGVTGGEEDGVDNSDVDSsklytQPEEVAFAYEELSKISPNfTIAAAFGNVHGVYKPGNVKL 236
Cdd:PLN02858 1212 TKSISSLahskGLMVEAELGRLSGTEDGLTVEEYEA-----KLTDVDQAKEFIDETGID-ALAVCIGNVHGKYPASGPNL 1285

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 518783285  237 EPKILRNSQDYIKQKfgtgdlPVNFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGV 299
Cdd:PLN02858 1286 RLDLLKELRALSSKK------GVLLVLHGASGLPESLIKECIENGVRKFNVNTEVRTAYMEAL 1342
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
21-341 5.37e-18

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 83.16  E-value: 5.37e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  21 IFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSnanqqaAIAGGISGAqhvhqmaalY 100
Cdd:PRK12738   9 LLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIY------ALCSAYSTT---------Y 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 101 EVPVILHTDHcaKKLLPWIDGLLDAGERyfdqygkplysSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTGG 180
Cdd:PRK12738  74 NMPLALHLDH--HESLDDIRRKVHAGVR-----------SAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGG 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 181 EEDgvdNSDVDS-SKLYTQPEEvAFAYEELSKISpnfTIAAAFGNVHGVYKPgnvklEPKILRNSQDYIKQKFgtgDLPV 259
Cdd:PRK12738 141 VED---DMSVDAeSAFLTDPQE-AKRFVELTGVD---SLAVAIGTAHGLYSK-----TPKIDFQRLAEIREVV---DVPL 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 260 nfVFHGGSGSSREEIREAIEYGAIKMNIDTDMQWSTWEGVLNYYKAkegylqsqlgNPEGAdspnkkyyDPRVWLRKGEE 339
Cdd:PRK12738 206 --VLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAE----------NPQGN--------DPRYYMRVGMD 265


                 ..
gi 518783285 340 SM 341
Cdd:PRK12738 266 AM 267
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 25-343 4.50e-17

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 80.31  E-value: 4.50e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  25 ANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAIFYAGKSLSNANQQAAIAG-GISgaqhvhqmaalyeVP 103
Cdd:PRK07315  13 ARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCKNLIENLVESmGIT-------------VP 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 104 VILHTDHCAkkllpWIDGL--LDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTGGE 181
Cdd:PRK07315  80 VAIHLDHGH-----YEDALecIEVG-----------YTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGE 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 182 EDGVdnsdVDSSKLytQPEEVAFAyeeLSKISPNFtIAAAFGNVHGVYkPGNVK-LEPKILRNSQDYIKqkfgtgDLPVn 260
Cdd:PRK07315 144 EDGI----IGKGEL--APIEDAKA---MVETGIDF-LAAGIGNIHGPY-PENWEgLDLDHLEKLTEAVP------GFPI- 205

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 261 fVFHGGSGSSREEIREAIEYGAIKMNIDTDMQwstwegvLNYYKAKEGYLQSQLGNPegADSPNKKYYDPRVWLRKGEES 340
Cdd:PRK07315 206 -VLHGGSGIPDDQIQEAIKLGVAKVNVNTECQ-------IAFANATRKFARDYEANE--AEYDKKKLFDPRKFLAPGVKA 275


                 ...
gi 518783285 341 MIS 343
Cdd:PRK07315 276 IQA 278
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
19-292 1.17e-16

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 79.63  E-value: 1.17e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  19 SEIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNgGAIFYAGKSlsnanqqaaIAGGIsgaqhVHQMAA 98
Cdd:PRK05835   6 NEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASE-GAIKYMGID---------MAVGM-----VKIMCE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  99 LY-EVPVILHTDH------CAKKllpwidglLDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTL 171
Cdd:PRK05835  71 RYpHIPVALHLDHgttfesCEKA--------VKAG-----------FTSVMIDASHHAFEENLELTSKVVKMAHNAGVSV 131

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 172 EIELGVTGGEEDGVDNSDVDSskLYTQPEEVafayEELSKISPNFTIAAAFGNVHGVYK-PGNVKLE------------- 237
Cdd:PRK05835 132 EAELGRLMGIEDNISVDEKDA--VLVNPKEA----EQFVKESQVDYLAPAIGTSHGAFKfKGEPKLDferlqevkrltni 205

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 238 PKILRNSQ---DYIKQKF--GTGDLpvnfvfHGGSGSSREEIREAIEYGAIKMNIDTDMQ 292
Cdd:PRK05835 206 PLVLHGASaipDDVRKSYldAGGDL------KGSKGVPFEFLQESVKGGINKVNTDTDLR 259
gatY PRK07998
class II aldolase;
20-292 8.11e-15

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 73.64  E-value: 8.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285  20 EIFRHANENNYALPAVNVVGTNSVNAVLETAKAVNSPVIIQFSNGGAifyagkSLSNANQQAAIaggisgaqhVHQMAAL 99
Cdd:PRK07998   8 ILLDRIQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNA------QLSGYDYIYEI---------VKRHADK 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 100 YEVPVILHTDHcaKKLLPWIDGLLDAGeryfdqygkplYSSHMLDLSEEPIEENIEICAKYFERMAKLGMTLEIELGVTG 179
Cdd:PRK07998  73 MDVPVSLHLDH--GKTFEDVKQAVRAG-----------FTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAIL 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518783285 180 GEEDGvDNSDVDSsklYTQPEEVAFAYEElskiSPNFTIAAAFGNVHGvykpgnVKLEPKIlrnsqDYIKQKFGTGDLPV 259
Cdd:PRK07998 140 GKEDD-HVSEADC---KTEPEKVKDFVER----TGCDMLAVSIGNVHG------LEDIPRI-----DIPLLKRIAEVSPV 200

                        250       260       270
                 ....*....|....*....|....*....|...
gi 518783285 260 NFVFHGGSGSSREEIREAIEYGAIKMNIDTDMQ 292
Cdd:PRK07998 201 PLVIHGGSGIPPEILRSFVNYKVAKVNIASDLR 233
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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