|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
6-333 |
1.05e-170 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 477.27 E-value: 1.05e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 6 KKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPIDPKQLSKNKKDIFALYIACGIDPKKSVLFFQ 85
Cdd:PRK00927 1 KKRVLSGIQPTGKLHLGNYLGAIKNWVELQDEYECFFCIADLHALTVPQDPEELRENTRELAADYLACGIDPEKSTIFVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 86 SDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktanGMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVELT 165
Cdd:PRK00927 81 SHVPEHAELAWILNCITPLGELERMTQFKDKSAK-----QKENVSAGLFTYPVLMAADILLYKADLVPVGEDQKQHLELT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 166 RNLAIRLNNKFNTTYKIPEPYIPEVGAKIMSLTDPSKKMSKSDTNPKSAIYLLDDPEDAYKKILKAVTDSEG--KIYLSD 243
Cdd:PRK00927 156 RDIARRFNNLYGEVFPVPEPLIPKVGARVMGLDGPTKKMSKSDPNDNNTINLLDDPKTIAKKIKKAVTDSERlrEIRYDL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 244 E-KPGIKNLLTIYSALNDISLQESAEKFKNSN--YGEFKNAVAQCVKEFLIKIQDKYKNALN---QIETLSQEGAKKASE 317
Cdd:PRK00927 236 PnKPEVSNLLTIYSALSGESIEELEAEYEAGGkgYGDFKKDLAEAVVEFLAPIRERYEELLAdpaYLDEILAEGAEKARA 315
|
330
....*....|....*.
gi 518846815 318 VAQINLDMLLKGIGLR 333
Cdd:PRK00927 316 VASKTLKEVREAMGLL 331
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
4-333 |
3.72e-150 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 425.23 E-value: 3.72e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 4 SEKKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPIDPKQLSKNKKDIFALYIACGIDPKKSVLF 83
Cdd:COG0180 1 MSKKRVLSGIQPTGRLHLGNYLGALKNWVELQDEYECFFFIADLHALTTPQDPEELRENTREVAADYLAAGLDPEKSTIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 84 FQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktaNGMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVE 163
Cdd:COG0180 81 VQSDVPEHAELAWLLSCLTPLGELERMPQFKDKSAK----NGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 164 LTRNLAIRLNNKFNTTYKIPEPYIPEVGAKIMSLtDPSKKMSKSDtnpKSAIYLLDDPEDAYKKILKAVTDSEGKIYLSD 243
Cdd:COG0180 157 LTRDIARRFNHRYGEVFPEPEALIPEEGARIPGL-DGRKKMSKSY---GNTINLLDDPKEIRKKIKSAVTDSERLRYDDP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 244 EKPGIKNLLTIYSALNDI-SLQESAEKFKNSN--YGEFKNAVAQCVKEFLIKIQDKYKNALNQIETLSQ---EGAKKASE 317
Cdd:COG0180 233 GKPEVCNLFTIYSAFSGKeEVEELEAEYRAGGigYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEilaEGAEKARA 312
|
330
....*....|....*.
gi 518846815 318 VAQINLDMLLKGIGLR 333
Cdd:COG0180 313 IAAKTLAEVREAMGLL 328
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
8-289 |
6.97e-119 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 343.80 E-value: 6.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 8 TLLSGITATGKLTLANYIGAIKNMVKLQE-EYNNYIFIADLHALTLPI-DPKQLSKNKKDIFALYIACGIDPKKSVLFFQ 85
Cdd:cd00806 1 RVLSGIQPSGSLHLGHYLGAFRFWVWLQEaGYELFFFIADLHALTVKQlDPEELRQNTRENAKDYLACGLDPEKSTIFFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 86 SDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktangMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVELT 165
Cdd:cd00806 81 SDVPEHYELAWLLSCVVTFGELERMTGFKDKSAQ------GESVNIGLLTYPVLQAADILLYKACLVPVGIDQDPHLELT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 166 RNLAIRLNNKFNTTYKIPEPYIPEvGAKIMSLTDPSKKMSKSDtnPKSAIYLLDDPEDAYKKILKAVTDSEGKI-YLSDE 244
Cdd:cd00806 155 RDIARRFNKLYGEIFPKPAALLSK-GAFLPGLQGPSKKMSKSD--PNNAIFLTDSPKEIKKKIMKAATDGGRTEhRRDGG 231
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 518846815 245 KPGIKNLLTIYSALNDISLQESAE----KFKNSNYGEFKNAVAQCVKEF 289
Cdd:cd00806 232 GPGVSNLVEIYSAFFNDDDEELEEideyRSGGLGYGECKKLLAEAIQEF 280
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
5-332 |
9.68e-114 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 332.76 E-value: 9.68e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 5 EKKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPI-DPKQLSKNKKDIFALYIACGIDPKKSVLF 83
Cdd:TIGR00233 1 KKFRVLTGIQPSGKMHLGHYLGAIQTKWLQQFGVELFICIADLHAITVKQtDPDALRKAREELAADYLAVGLDPEKTFIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 84 FQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktangmETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVE 163
Cdd:TIGR00233 81 LQSDYPEHYELAWLLSCQVTFGELKRMTQFKDKSQA-------ENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 164 LTRNLAIRLNNKFNTTYKIPEPYIPEVGAKIMSLTDpsKKMSKSDtnPKSAIYLLDDPEDAYKKILKAVTDSEGKIYLSD 243
Cdd:TIGR00233 154 LTRDLAERFNKKFKNFFPKPESLISKFFPRLMGLSG--KKMSKSD--PNSAIFLTDTPKQIKKKIRKAATDGGRVTLFEH 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 244 -EKPGIKNLLTIYSAL-----NDISLQESAEKFKN--SNYGEFKNAVAQCVKEFLIKIQDKYKN-ALNQIETLSQEGAKK 314
Cdd:TIGR00233 230 rEKPGVPNLLVIYQYLsffliDDDKLKEIYEAYKSgkLGYGECKKALIEVLQEFLKEIQERRAEiAEEILDKILEPGAKK 309
|
330
....*....|....*...
gi 518846815 315 ASEVAQINLDMLLKGIGL 332
Cdd:TIGR00233 310 ARETANKTLADVYKAMGL 327
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
2-290 |
6.45e-69 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 217.14 E-value: 6.45e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 2 QNSEKKTLLSGITATGKLTLAnYIGAIKNMVKLQE-EYNNYIFIADLHALTLPIDPKQLSKNKKDIFAL------YIACG 74
Cdd:pfam00579 1 KKNRPLRVYSGIDPTGPLHLG-YLVPLMKLRQFQQaGHEVFFLIGDLHAIIGDPSKSPERKLLSRETVLenaikaQLACG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 75 IDPKKSVLFFQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKIKTANGmetIPTGILMYPTLMVGDILLYNADIIPV 154
Cdd:pfam00579 80 LDPEKAEIVNNSDWLEHLELAWLLRDLGKHFSLNRMLQFKDVKKRLEQGPG---ISLGEFTYPLLQAYDILLLKADLQPG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 155 GIDQKQHVELTRNLAIRLNNKFnttYKIPEPYIPevgaKIMSLTDPSKKMSKSDtnPKSAIYLLDDPEDAYKKILKAVTD 234
Cdd:pfam00579 157 GSDQWGNIELGRDLARRFNKKI---FKKPVGLTN----PLLTGLDGGKKMSKSA--GNSAIFLDDDPESVYKKIQKAYTD 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 518846815 235 SEGKI-YLSDEKPGIKN-LLTIYSALNDISLQESAEKF------KNSNYGEFKNAVAQCVKEFL 290
Cdd:pfam00579 228 PDREVrKDLKLFTFLSNeEIEILEAELGKSPYREAEELlarevtGLVHGGDLKKAAAEAVNKLL 291
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK00927 |
PRK00927 |
tryptophanyl-tRNA synthetase; Reviewed |
6-333 |
1.05e-170 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 234866 [Multi-domain] Cd Length: 333 Bit Score: 477.27 E-value: 1.05e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 6 KKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPIDPKQLSKNKKDIFALYIACGIDPKKSVLFFQ 85
Cdd:PRK00927 1 KKRVLSGIQPTGKLHLGNYLGAIKNWVELQDEYECFFCIADLHALTVPQDPEELRENTRELAADYLACGIDPEKSTIFVQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 86 SDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktanGMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVELT 165
Cdd:PRK00927 81 SHVPEHAELAWILNCITPLGELERMTQFKDKSAK-----QKENVSAGLFTYPVLMAADILLYKADLVPVGEDQKQHLELT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 166 RNLAIRLNNKFNTTYKIPEPYIPEVGAKIMSLTDPSKKMSKSDTNPKSAIYLLDDPEDAYKKILKAVTDSEG--KIYLSD 243
Cdd:PRK00927 156 RDIARRFNNLYGEVFPVPEPLIPKVGARVMGLDGPTKKMSKSDPNDNNTINLLDDPKTIAKKIKKAVTDSERlrEIRYDL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 244 E-KPGIKNLLTIYSALNDISLQESAEKFKNSN--YGEFKNAVAQCVKEFLIKIQDKYKNALN---QIETLSQEGAKKASE 317
Cdd:PRK00927 236 PnKPEVSNLLTIYSALSGESIEELEAEYEAGGkgYGDFKKDLAEAVVEFLAPIRERYEELLAdpaYLDEILAEGAEKARA 315
|
330
....*....|....*.
gi 518846815 318 VAQINLDMLLKGIGLR 333
Cdd:PRK00927 316 VASKTLKEVREAMGLL 331
|
|
| TrpS |
COG0180 |
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; ... |
4-333 |
3.72e-150 |
|
Tryptophanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Tryptophanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439950 [Multi-domain] Cd Length: 330 Bit Score: 425.23 E-value: 3.72e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 4 SEKKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPIDPKQLSKNKKDIFALYIACGIDPKKSVLF 83
Cdd:COG0180 1 MSKKRVLSGIQPTGRLHLGNYLGALKNWVELQDEYECFFFIADLHALTTPQDPEELRENTREVAADYLAAGLDPEKSTIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 84 FQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktaNGMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVE 163
Cdd:COG0180 81 VQSDVPEHAELAWLLSCLTPLGELERMPQFKDKSAK----NGKENVNAGLLTYPVLMAADILLYKADLVPVGEDQKQHLE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 164 LTRNLAIRLNNKFNTTYKIPEPYIPEVGAKIMSLtDPSKKMSKSDtnpKSAIYLLDDPEDAYKKILKAVTDSEGKIYLSD 243
Cdd:COG0180 157 LTRDIARRFNHRYGEVFPEPEALIPEEGARIPGL-DGRKKMSKSY---GNTINLLDDPKEIRKKIKSAVTDSERLRYDDP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 244 EKPGIKNLLTIYSALNDI-SLQESAEKFKNSN--YGEFKNAVAQCVKEFLIKIQDKYKNALNQIETLSQ---EGAKKASE 317
Cdd:COG0180 233 GKPEVCNLFTIYSAFSGKeEVEELEAEYRAGGigYGDLKKALAEAVVEFLAPIRERRAELLADPAELDEilaEGAEKARA 312
|
330
....*....|....*.
gi 518846815 318 VAQINLDMLLKGIGLR 333
Cdd:COG0180 313 IAAKTLAEVREAMGLL 328
|
|
| TrpRS_core |
cd00806 |
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) ... |
8-289 |
6.97e-119 |
|
catalytic core domain of tryptophanyl-tRNA synthetase; Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. TrpRS is a homodimer which attaches Tyr to the appropriate tRNA. TrpRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding
Pssm-ID: 173903 [Multi-domain] Cd Length: 280 Bit Score: 343.80 E-value: 6.97e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 8 TLLSGITATGKLTLANYIGAIKNMVKLQE-EYNNYIFIADLHALTLPI-DPKQLSKNKKDIFALYIACGIDPKKSVLFFQ 85
Cdd:cd00806 1 RVLSGIQPSGSLHLGHYLGAFRFWVWLQEaGYELFFFIADLHALTVKQlDPEELRQNTRENAKDYLACGLDPEKSTIFFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 86 SDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktangMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVELT 165
Cdd:cd00806 81 SDVPEHYELAWLLSCVVTFGELERMTGFKDKSAQ------GESVNIGLLTYPVLQAADILLYKACLVPVGIDQDPHLELT 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 166 RNLAIRLNNKFNTTYKIPEPYIPEvGAKIMSLTDPSKKMSKSDtnPKSAIYLLDDPEDAYKKILKAVTDSEGKI-YLSDE 244
Cdd:cd00806 155 RDIARRFNKLYGEIFPKPAALLSK-GAFLPGLQGPSKKMSKSD--PNNAIFLTDSPKEIKKKIMKAATDGGRTEhRRDGG 231
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 518846815 245 KPGIKNLLTIYSALNDISLQESAE----KFKNSNYGEFKNAVAQCVKEF 289
Cdd:cd00806 232 GPGVSNLVEIYSAFFNDDDEELEEideyRSGGLGYGECKKLLAEAIQEF 280
|
|
| PLN02886 |
PLN02886 |
aminoacyl-tRNA ligase |
6-323 |
3.37e-114 |
|
aminoacyl-tRNA ligase
Pssm-ID: 215478 [Multi-domain] Cd Length: 389 Bit Score: 336.02 E-value: 3.37e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 6 KKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPIDPKQLSKNKKDIFALYIACGIDPKKSVLFFQ 85
Cdd:PLN02886 46 KKRVVSGVQPTGSIHLGNYLGAIKNWVALQETYDTFFCVVDLHAITLPHDPRELGKATRSTAAIYLACGIDPSKASVFVQ 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 86 SDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktaNGMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVELT 165
Cdd:PLN02886 126 SHVPAHAELMWLLSCSTPIGWLNKMIQFKEKSRK----AGDENVGVGLLTYPVLMASDILLYQADLVPVGEDQKQHLELT 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 166 RNLAIRLNNKFN------------TTYKIPEPYIPEVGAKIMSLTDPSKKMSKSDTNPKSAIYLLDDPEDAYKKILKAVT 233
Cdd:PLN02886 202 RDIAERVNNLYGgrkwkklggrggSVFKVPEALIPPAGARVMSLTDGTSKMSKSAPSDQSRINLLDPPDVIANKIKRCKT 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 234 DS-EGKIYLSDEKPGIKNLLTIYSALNDISLQESAEKFKNSNYGEFKNAVAQCVKEFLIKIQDKYKNALNQIETLSQ--- 309
Cdd:PLN02886 282 DSfPGLEFDNPERPECNNLLSIYQLVTGKTKEEVLAECGDMRWGDFKPLLTDALIEHLSPIQVRYEEIMSDPSYLDSvlk 361
|
330
....*....|....
gi 518846815 310 EGAKKASEVAQINL 323
Cdd:PLN02886 362 EGADAAAEIADRTL 375
|
|
| trpS |
TIGR00233 |
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members ... |
5-332 |
9.68e-114 |
|
tryptophanyl-tRNA synthetase; This model represents tryptophanyl-tRNA synthetase. Some members of the family have a pfam00458 domain amino-terminal to the region described by this model. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272975 [Multi-domain] Cd Length: 327 Bit Score: 332.76 E-value: 9.68e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 5 EKKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPI-DPKQLSKNKKDIFALYIACGIDPKKSVLF 83
Cdd:TIGR00233 1 KKFRVLTGIQPSGKMHLGHYLGAIQTKWLQQFGVELFICIADLHAITVKQtDPDALRKAREELAADYLAVGLDPEKTFIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 84 FQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKiktangmETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVE 163
Cdd:TIGR00233 81 LQSDYPEHYELAWLLSCQVTFGELKRMTQFKDKSQA-------ENVPIGLLSYPVLQAADILLYQADLVPVGIDQDQHLE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 164 LTRNLAIRLNNKFNTTYKIPEPYIPEVGAKIMSLTDpsKKMSKSDtnPKSAIYLLDDPEDAYKKILKAVTDSEGKIYLSD 243
Cdd:TIGR00233 154 LTRDLAERFNKKFKNFFPKPESLISKFFPRLMGLSG--KKMSKSD--PNSAIFLTDTPKQIKKKIRKAATDGGRVTLFEH 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 244 -EKPGIKNLLTIYSAL-----NDISLQESAEKFKN--SNYGEFKNAVAQCVKEFLIKIQDKYKN-ALNQIETLSQEGAKK 314
Cdd:TIGR00233 230 rEKPGVPNLLVIYQYLsffliDDDKLKEIYEAYKSgkLGYGECKKALIEVLQEFLKEIQERRAEiAEEILDKILEPGAKK 309
|
330
....*....|....*...
gi 518846815 315 ASEVAQINLDMLLKGIGL 332
Cdd:TIGR00233 310 ARETANKTLADVYKAMGL 327
|
|
| PRK12282 |
PRK12282 |
tryptophanyl-tRNA synthetase II; Reviewed |
6-332 |
2.04e-73 |
|
tryptophanyl-tRNA synthetase II; Reviewed
Pssm-ID: 183400 [Multi-domain] Cd Length: 333 Bit Score: 229.74 E-value: 2.04e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 6 KKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTL-PIDPKQLSKNKKDIFALYIACGIDPKKSVLFF 84
Cdd:PRK12282 2 KPIILTGDRPTGKLHLGHYVGSLKNRVALQNEHEQFVLIADQQALTDnAKNPEKIRRNILEVALDYLAVGIDPAKSTIFI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 85 QSDVIQHGLMNWLILTNTTIGELSRMTQFKDksaKIKTANGMETIPTGILMYPTLMVGDILLYNADIIPVGIDQKQHVEL 164
Cdd:PRK12282 82 QSQIPELAELTMYYMNLVTVARLERNPTVKT---EIAQKGFGRSIPAGFLTYPVSQAADITAFKATLVPVGDDQLPMIEQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 165 TRNLAIRLNNKFNT-TYKIPEPYIPEVGaKIMSLtDPSKKMSKSDTNpksAIYLLDDPEDAYKKILKAVTDSeGKIYLSD 243
Cdd:PRK12282 159 TREIVRRFNSLYGTdVLVEPEALLPEAG-RLPGL-DGKAKMSKSLGN---AIYLSDDADTIKKKVMSMYTDP-NHIRVED 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 244 E-KPGIKNLLTIYSAL--NDISLQESAEKFKNSNYGEF--KNAVAQCVKEFLIKIQDKYKNALNQIETLSQ---EGAKKA 315
Cdd:PRK12282 233 PgKVEGNVVFTYLDAFdpDKAEVAELKAHYQRGGLGDVkcKRYLEEVLQELLAPIRERRAEFAKDPGYVLEilkAGSEKA 312
|
330
....*....|....*..
gi 518846815 316 SEVAQINLDMLLKGIGL 332
Cdd:PRK12282 313 REVAAQTLSEVKDAMGL 329
|
|
| tRNA-synt_1b |
pfam00579 |
tRNA synthetases class I (W and Y); |
2-290 |
6.45e-69 |
|
tRNA synthetases class I (W and Y);
Pssm-ID: 395461 [Multi-domain] Cd Length: 292 Bit Score: 217.14 E-value: 6.45e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 2 QNSEKKTLLSGITATGKLTLAnYIGAIKNMVKLQE-EYNNYIFIADLHALTLPIDPKQLSKNKKDIFAL------YIACG 74
Cdd:pfam00579 1 KKNRPLRVYSGIDPTGPLHLG-YLVPLMKLRQFQQaGHEVFFLIGDLHAIIGDPSKSPERKLLSRETVLenaikaQLACG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 75 IDPKKSVLFFQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKIKTANGmetIPTGILMYPTLMVGDILLYNADIIPV 154
Cdd:pfam00579 80 LDPEKAEIVNNSDWLEHLELAWLLRDLGKHFSLNRMLQFKDVKKRLEQGPG---ISLGEFTYPLLQAYDILLLKADLQPG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 155 GIDQKQHVELTRNLAIRLNNKFnttYKIPEPYIPevgaKIMSLTDPSKKMSKSDtnPKSAIYLLDDPEDAYKKILKAVTD 234
Cdd:pfam00579 157 GSDQWGNIELGRDLARRFNKKI---FKKPVGLTN----PLLTGLDGGKKMSKSA--GNSAIFLDDDPESVYKKIQKAYTD 227
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 518846815 235 SEGKI-YLSDEKPGIKN-LLTIYSALNDISLQESAEKF------KNSNYGEFKNAVAQCVKEFL 290
Cdd:pfam00579 228 PDREVrKDLKLFTFLSNeEIEILEAELGKSPYREAEELlarevtGLVHGGDLKKAAAEAVNKLL 291
|
|
| PRK12556 |
PRK12556 |
tryptophanyl-tRNA synthetase; Provisional |
6-332 |
2.95e-60 |
|
tryptophanyl-tRNA synthetase; Provisional
Pssm-ID: 183592 [Multi-domain] Cd Length: 332 Bit Score: 196.10 E-value: 2.95e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 6 KKTLLSGITATGKLTLANYIGAIKNMVKLQEEYNN--YIFIADLHALTLPIDPKQLSKNKKDIFALYIACGIDPKKSVLF 83
Cdd:PRK12556 3 EKIMLTGIKPTGYPHLGNYIGAIKPALQMAKNYEGkaLYFIADYHALNAVHDPEQFRSYTREVAATWLSLGLDPEDVIFY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 84 FQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKIKTAnGMEtIPTGILM----YPTLMVGDILLYNADIIPVGIDQK 159
Cdd:PRK12556 83 RQSDVPEIFELAWILSCLTPKGLMNRAHAYKAKVDQNKEA-GLD-LDAGVNMglytYPILMAADILLFQATHVPVGKDQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 160 QHVELTRNLAIRLNNKFNTTYKIPEPYIPEvGAKIMSLTDpSKKMSKSDTNpksAIYLLDDPEDAYKKILKAVTDSegkI 239
Cdd:PRK12556 161 QHIEIARDIATYFNHTFGDTFTLPEYVIQE-EGAILPGLD-GRKMSKSYGN---VIPLFAEQEKLRKLIFKIKTDS---S 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 240 YLSDEK-PGIKNLLTIYSALNDIS-LQESAEKFKNS-NYGEFKNAVAQCVKEFLIKIQDKYKNALN---QIETLSQEGAK 313
Cdd:PRK12556 233 LPNEPKdPETSALFTIYKEFATEEeVQSMREKYETGiGWGDVKKELFRVVDRELAGPREKYAMYMNepsLLDEALEKGAE 312
|
330
....*....|....*....
gi 518846815 314 KASEVAQINLDMLLKGIGL 332
Cdd:PRK12556 313 RAREIAKPNLAEIKKAIGF 331
|
|
| PRK12284 |
PRK12284 |
tryptophanyl-tRNA synthetase; Reviewed |
10-333 |
2.86e-42 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237036 [Multi-domain] Cd Length: 431 Bit Score: 151.70 E-value: 2.86e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 10 LSGITATGKLTLANYIGAIKNMVK--LQEEYNNYIFIADLHALTLPIDPKQLSKNKKDIFALYIACGIDPKKSVLFFQSD 87
Cdd:PRK12284 6 LTGITTTGTPHLGNYAGAIRPAIAasRQPGVESFYFLADYHALIKCDDPARIQRSTLEIAATWLAAGLDPERVTFYRQSD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 88 VIQHGLMNWLILTNTTIGELSRMTQFK---DKSakikTANGMET---IPTGILMYPTLMVGDILLYNADIIPVGIDQKQH 161
Cdd:PRK12284 86 IPEIPELTWLLTCVAGKGLLNRAHAYKaavDKN----VAAGEDPdagVTAGLFMYPVLMAADILMFNAHKVPVGRDQIQH 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 162 VELTRNLAIRLNNKFNTTY-KIPEPYIPEVGAKIMSLTdpSKKMSKSDTNpksAIYLLDDPEDAYKKILKAVTDS----E 236
Cdd:PRK12284 162 IEMARDIAQRFNHLYGGEFfVLPEAVIEESVATLPGLD--GRKMSKSYDN---TIPLFAPREELKKAIFSIVTDSrapgE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 237 GKiylsdeKPGIKNLLTIYSALNdiSLQESAEkFKNS-----NYGEFKNAVAQCVKEFLIKIQDKYKNALNQ---IETLS 308
Cdd:PRK12284 237 PK------DTEGSALFQLYQAFA--TPEETAA-FRQAladgiGWGDAKQRLFERIDRELAPMRERYEALIARpadIEDIL 307
|
330 340
....*....|....*....|....*
gi 518846815 309 QEGAKKASEVAQINLDMLLKGIGLR 333
Cdd:PRK12284 308 LAGAAKARRIATPFLAELREAVGLR 332
|
|
| PRK12283 |
PRK12283 |
tryptophanyl-tRNA synthetase; Reviewed |
10-332 |
6.19e-41 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 183401 [Multi-domain] Cd Length: 398 Bit Score: 147.41 E-value: 6.19e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 10 LSGITATGKLTLANYIGAIKNMVKLQEEYNNYIFIADLHALTLPID-PKQLSKNKKDIFALYIACGIDPKKSVLFFQSDV 88
Cdd:PRK12283 6 LSGMRPTGRLHLGHYHGVLKNWVKLQHEYECFFFVADWHALTTHYEtPEVIEKNVWDMVIDWLAAGVDPAQATLFIQSKV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 89 IQHGLMNWLILTNTTIGELSRMTQFKDKSAKIKTANgMETIptGILMYPTLMVGDILLYNADIIPVGIDQKQHVELTRNL 168
Cdd:PRK12283 86 PEHAELHLLLSMITPLGWLERVPTYKDQQEKLKEKD-LSTY--GFLGYPLLQSADILIYRAGLVPVGEDQVPHVEMTREI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 169 AIRlnnkFNTTY-KIP------EPYIPEVGAK------------------------------------------------ 193
Cdd:PRK12283 163 ARR----FNHLYgREPgfeekaEAAIKKLGKKraklyhelrnayqeegddealeqarallqeqqnlsmgdrerlfgyleg 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 194 ----IMS-----LTDPSK-------KMSKSDTNpksAIYLLDDPEDAYKKILKAVTDSeGKIYLSD----EKPGIKNLLT 253
Cdd:PRK12283 239 agkiILPepqalLTEASKmpgldgqKMSKSYGN---TIGLREDPESVTKKIRTMPTDP-ARVRRTDpgdpEKCPVWQLHQ 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 254 IYSalNDISLQESAEKFKNSNYG--EFKNAVAQCVKEFLIKIQD---KYKNALNQIETLSQEGAKKASEVAQINLDMLLK 328
Cdd:PRK12283 315 VYS--DEETKEWVQKGCRSAGIGclECKQPVIDAILREQQPMREraqKYEDDPSLVRAIVADGCEKARKVARETMRDVRE 392
|
....
gi 518846815 329 GIGL 332
Cdd:PRK12283 393 AMGL 396
|
|
| Tyr_Trp_RS_core |
cd00395 |
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA ... |
8-289 |
3.13e-40 |
|
catalytic core domain of tyrosinyl-tRNA and tryptophanyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS)/Tryptophanyl-tRNA synthetase (TrpRS) catalytic core domain. These enzymes attach Tyr or Trp, respectively, to the appropriate tRNA. These class I enzymes are homodimers, which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173893 [Multi-domain] Cd Length: 273 Bit Score: 142.44 E-value: 3.13e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 8 TLLSGITATGK-LTLANYIGaIKNMVKLQE-EYNNYIFIADLHALT----------LPIDPKQLSKNKKDIFALYIACGI 75
Cdd:cd00395 1 TLYCGIDPTADsLHIGHLIG-LLTFRRFQHaGHRPIFLIGGQTGIIgdpsgkkserTLNDPEEVRQNIRRIAAQYLAVGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 76 D--PKKSVLFFQSDV---IQHGLMNWLILTNTTIGELSRMTQFKDKSAkiktangmETIPTGILMYPTLMVGDILLYN-- 148
Cdd:cd00395 80 FedPTQATLFNNSDWpgpLAHIQFLRDLGKHVYVNYMERKTSFQSRSE--------EGISATEFTYPPLQAADFLLLNtt 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 149 --ADIIPVGIDQKQHVELTRNLAIRLNNkfnttYKIPEPYIPevgAKIMSLTDPskKMSKSDTNPKSAIYLLDDPEDAYK 226
Cdd:cd00395 152 egCDIQPGGSDQWGNITLGRELARRFNG-----FTIAEGLTI---PLVTKLDGP--KFGKSESGPKWLDTEKTSPYEFYQ 221
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518846815 227 KILKAVtdsegkiylsdekpgIKNLLTIYSALNDISLQE----SAEKFKNSNYGEFKNAVAQCVKEF 289
Cdd:cd00395 222 FWINAV---------------DSDVINILKYFTFLSKEEierlEQEQYEAPGYRVAQKTLAEEVTKT 273
|
|
| PRK12285 |
PRK12285 |
tryptophanyl-tRNA synthetase; Reviewed |
1-307 |
3.57e-26 |
|
tryptophanyl-tRNA synthetase; Reviewed
Pssm-ID: 237037 [Multi-domain] Cd Length: 368 Bit Score: 106.87 E-value: 3.57e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 1 MQNSEKKTLLSGITATGKLTLANYIgAIKNMVKLQEE-YNNYIFIADLHA-LTLPIDPKQLSKNKKDIFALYIACGIDPK 78
Cdd:PRK12285 61 YRNGKPFAVYTGFMPSGPMHIGHKM-VFDELKWHQEFgANVYIPIADDEAyAARGLSWEETREWAYEYILDLIALGFDPD 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 79 KSVLFFQSDviqhglmnwliltNTTIGELSRMTqfkdkSAKIkTANGMETI-----PT--GILMYPTLMVGDILLYNAD- 150
Cdd:PRK12285 140 KTEIYFQSE-------------NIKVYDLAFEL-----AKKV-NFSELKAIygftgETniGHIFYPATQAADILHPQLEe 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 151 -----IIPVGIDQKQHVELTRNLAIRLNNKFN-----TTY-KIpepyipevgakIMSLTdpSKKMSKSdtNPKSAIYLLD 219
Cdd:PRK12285 201 gpkptLVPVGIDQDPHIRLTRDIAERLHGGYGfikpsSTYhKF-----------MPGLT--GGKMSSS--KPESAIYLTD 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 220 DPEDAYKKILKAVTDSEGKIYLSDEKPG------IKNLLTIYSALNDISLQESAEKFKNSNY--GEFKNAVAQCVKEFLI 291
Cdd:PRK12285 266 DPETVKKKIMKALTGGRATLEEQRKLGGepdecvVYELLLYHLEEDDKELKEIYEECRSGELlcGECKKEAAEKIAEFLK 345
|
330
....*....|....*.
gi 518846815 292 KIQDKYKNALNQIETL 307
Cdd:PRK12285 346 EHQEKREEAREILEKY 361
|
|
| PRK08560 |
PRK08560 |
tyrosyl-tRNA synthetase; Validated |
12-231 |
1.09e-11 |
|
tyrosyl-tRNA synthetase; Validated
Pssm-ID: 236286 [Multi-domain] Cd Length: 329 Bit Score: 64.89 E-value: 1.09e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 12 GITATGKLTLANYIGAIKnMVKLQEE-YNNYIFIADLHALtlpIDPK-------QLSKNKKDIFalyIACGIDPKKSVLF 83
Cdd:PRK08560 36 GFEPSGKIHLGHLLTMNK-LADLQKAgFKVTVLLADWHAY---LNDKgdleeirKVAEYNKKVF---EALGLDPDKTEFV 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 84 FQSDvIQHGLMNWLIL----TNTTigeLSRMTqfkdKSAKIkTANGMETIPTGILMYPTLMVGDILLYNADIIPVGIDQ- 158
Cdd:PRK08560 109 LGSE-FQLDKEYWLLVlklaKNTT---LARAR----RSMTI-MGRRMEEPDVSKLVYPLMQVADIFYLDVDIAVGGMDQr 179
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518846815 159 KQHVeLTRNLAIRLNnkfnttYKIP----EPYIPevgakimSLTDPSKKMSKSDtnPKSAIYLLDDPEDAYKKILKA 231
Cdd:PRK08560 180 KIHM-LAREVLPKLG------YKKPvcihTPLLT-------GLDGGGIKMSKSK--PGSAIFVHDSPEEIRRKIKKA 240
|
|
| PTZ00126 |
PTZ00126 |
tyrosyl-tRNA synthetase; Provisional |
134-231 |
4.14e-08 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 240282 [Multi-domain] Cd Length: 383 Bit Score: 54.31 E-value: 4.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 134 LMYPTLMVGDILLYNADIIPVGIDQKQHVELTRnlairlnnKFNTTYKIPEPYIPEVGAKIMSLTDPSKKMSKSdtNPKS 213
Cdd:PTZ00126 196 ILYPCMQCADIFYLKADICQLGMDQRKVNMLAR--------EYCDKKKIKKKPIILSHHMLPGLLEGQEKMSKS--DPNS 265
|
90
....*....|....*...
gi 518846815 214 AIYLLDDPEDAYKKILKA 231
Cdd:PTZ00126 266 AIFMEDSEEDVNRKIKKA 283
|
|
| PLN02486 |
PLN02486 |
aminoacyl-tRNA ligase |
62-230 |
7.03e-08 |
|
aminoacyl-tRNA ligase
Pssm-ID: 178104 Cd Length: 383 Bit Score: 53.59 E-value: 7.03e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 62 NKKDIfalyIACGIDPKKSVLFfqSDViqhglmnwliltNTTIGELsrmtqFKD--KSAKIKTANGMETI-------PTG 132
Cdd:PLN02486 136 NAKDI----IACGFDVERTFIF--SDF------------DYVGGAF-----YKNmvKIAKCVTLNQVRGIfgfsgedNIG 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 133 ILMYPTLMVG-------DILLYNAD----IIPVGIDQKQHVELTRNLAIRLnnKFNTTYKIPEPYIPevgakimSLTDPS 201
Cdd:PLN02486 193 KISFPAVQAApsfpssfPHLFGGKDklrcLIPCAIDQDPYFRMTRDVAPRL--GYYKPALIESRFFP-------ALQGES 263
|
170 180
....*....|....*....|....*....
gi 518846815 202 KKMSKSDTNpkSAIYLLDDPEDAYKKILK 230
Cdd:PLN02486 264 GKMSASDPN--SAIYVTDTPKEIKNKINK 290
|
|
| PTZ00348 |
PTZ00348 |
tyrosyl-tRNA synthetase; Provisional |
5-231 |
8.89e-06 |
|
tyrosyl-tRNA synthetase; Provisional
Pssm-ID: 173541 [Multi-domain] Cd Length: 682 Bit Score: 47.20 E-value: 8.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 5 EKKTLL---SGITATGKLTLANYIGAIKNMVKLQEEYNNYIF-IADLHALTLPIDPKQLSKNK---KDIFALYIACGIDP 77
Cdd:PTZ00348 28 EKKPLIrcyDGFEPSGRMHIAQGIFKAVNVNKCTQAGCEFVFwVADWFALMNDKVGGELEKIRivgRYLIEVWKAAGMDM 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 78 KKSVLFFQSDVI-QHGLMNWliltnTTIGELSRmtqfKDKSAKIK---TANGME--TIPTGILMYPTLMVGDILLYNADI 151
Cdd:PTZ00348 108 DKVLFLWSSEEItNHANTYW-----RTVLDIGR----QNTIARIKkccTIMGKTegTLTAAQVLYPLMQCADIFFLKADI 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 152 IPVGIDQKQHVELTRNLAIRLNNKFNttykipepyiPEVGAKIM--SLTDPSKKMSKSDtnPKSAIYLLDDPEDAYKKIL 229
Cdd:PTZ00348 179 CQLGLDQRKVNMLAREYCDLIGRKLK----------PVILSHHMlaGLKQGQAKMSKSD--PDSAIFMEDTEEDVARKIR 246
|
..
gi 518846815 230 KA 231
Cdd:PTZ00348 247 QA 248
|
|
| class_I_aaRS_core |
cd00802 |
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA ... |
136-208 |
1.29e-04 |
|
catalytic core domain of class I amino acyl-tRNA synthetase; Class I amino acyl-tRNA synthetase (aaRS) catalytic core domain. These enzymes are mostly monomers which aminoacylate the 2'-OH of the nucleotide at the 3' of the appropriate tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formation of the enzyme bound aminoacyl-adenylate. It contains the characteristic class I HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173901 [Multi-domain] Cd Length: 143 Bit Score: 41.31 E-value: 1.29e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 518846815 136 YPTLMVGDILLYN---ADIIPVGIDQKQHVELTRNLAIRLNNKfnttyKIPEPYIPEvgakiMSLTDPSKKMSKSD 208
Cdd:cd00802 78 YMFLQAADFLLLYeteCDIHLGGSDQLGHIELGLELLKKAGGP-----ARPFGLTFG-----RVMGADGTKMSKSK 143
|
|
| TyrRS_core |
cd00805 |
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) ... |
134-283 |
2.05e-04 |
|
catalytic core domain of tyrosinyl-tRNA synthetase; Tyrosinyl-tRNA synthetase (TyrRS) catalytic core domain. TyrRS is a homodimer which attaches Tyr to the appropriate tRNA. TyrRS is a class I tRNA synthetases, so it aminoacylates the 2'-OH of the nucleotide at the 3' end of the tRNA. The core domain is based on the Rossman fold and is responsible for the ATP-dependent formationof the enzyme bound aminoacyl-adenylate. It contains the class I characteristic HIGH and KMSKS motifs, which are involved in ATP binding.
Pssm-ID: 173902 [Multi-domain] Cd Length: 269 Bit Score: 42.21 E-value: 2.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 134 LMYPTLMVGDILLYNADIIPVGIDQKQHVELTRNLAIRLNNKfnttykipepyipevgaKIMSLTDP------SKKMSKS 207
Cdd:cd00805 137 FIYPLLQAYDFVYLDVDLQLGGSDQRGNITLGRDLIRKLGYK-----------------KVVGLTTPlltgldGGKMSKS 199
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 518846815 208 DTNPKSaIYLLDDPEDAYKKILKAvtdsegkiylSDekPGIKNLLTIYSALNDISLQESAEKFKNS-NYGEFKNAVA 283
Cdd:cd00805 200 EGNAIW-DPVLDSPYDVYQKIRNA----------FD--PDVLEFLKLFTFLDYEEIEELEEEHAEGpLPRDAKKALA 263
|
|
| tyrS |
TIGR00234 |
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up ... |
5-234 |
8.06e-04 |
|
tyrosyl-tRNA synthetase; This tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 272976 [Multi-domain] Cd Length: 378 Bit Score: 40.84 E-value: 8.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 5 EKKTLLSGITATG-KLTLANYIgAIKNMVKLQEE-YNNYIFIADLHALT----------LPIDPKQLSKNKKDIFAlYIA 72
Cdd:TIGR00234 30 RPLKLYLGFDPTApSLHLGHLV-PLLKLRDFQQAgHEVIVLLGDFTALIgdptgksevrKILTREEVQENAENIKK-QIA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 73 CGIDPKKSVLFFQSDVIQHGLMNWLILTNTTIGELSRMTQFKDKSAKIKTANG-METIptgilmYPTLMVGDILLYNADI 151
Cdd:TIGR00234 108 RFLDFEKAKFVYNSEWLLKLNYTDFIRLLGKIFTVNRMLRRDAFSSRFEENISlHEFI------YPLLQAYDFVYLNVDL 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 518846815 152 IPVGIDQKQHVELTRNLAIRLNNkfNTTYKIPEPYIPEVGAKIMSLTDpSKKMSKSDTNPKSAIYLLDDPEDAYKKILKA 231
Cdd:TIGR00234 182 QLGGSDQWFNIRKGRDLARENLP--SLQFGLTVPLLTPADGEKMGKSL-GGAVSLDEGKYDFYQKVINTPDELVKKYLKL 258
|
...
gi 518846815 232 VTD 234
Cdd:TIGR00234 259 FTF 261
|
|
| |
