NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|519054599|ref|WP_020210474|]
View 

class II fructose-bisphosphate aldolase [Gilvimarinus chinensis]

Protein Classification

class II fructose-bisphosphate aldolase( domain architecture ID 10013149)

class II fructose-1,6-bisphosphate (FBP) aldolase catalyzes the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate

EC:  4.1.2.13
Gene Ontology:  GO:0008270|GO:0004332|GO:0016832

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 11-353 0e+00

fructose-bisphosphate aldolase; Provisional


:

Pssm-ID: 236406  Cd Length: 350  Bit Score: 619.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  11 VILGDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQGSIKGAVSAAL 90
Cdd:PRK09197   3 VATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAGAK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  91 HVHSMAPVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTL 170
Cdd:PRK09197  83 HVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGMTL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 171 EIELGVTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQDHLSEQ 250
Cdd:PRK09197 163 EIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVSKK 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 251 FGLGHNPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNKKFYDPR 330
Cdd:PRK09197 243 FGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYDPR 322

                        330       340
                 ....*....|....*....|...
gi 519054599 331 VWLRKAEEGFSSKLTDICRQLNC 353
Cdd:PRK09197 323 VWLRAAEASMAARLEEAFEDLNS 345
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 11-353 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 619.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  11 VILGDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQGSIKGAVSAAL 90
Cdd:PRK09197   3 VATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAGAK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  91 HVHSMAPVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTL 170
Cdd:PRK09197  83 HVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGMTL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 171 EIELGVTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQDHLSEQ 250
Cdd:PRK09197 163 EIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVSKK 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 251 FGLGHNPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNKKFYDPR 330
Cdd:PRK09197 243 FGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYDPR 322

                        330       340
                 ....*....|....*....|...
gi 519054599 331 VWLRKAEEGFSSKLTDICRQLNC 353
Cdd:PRK09197 323 VWLRAAEASMAARLEEAFEDLNS 345
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 14-353 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 578.17  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  14 GDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQGSIKGAVSAALHVH 93
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  94 SMAPVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIE 173
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 174 LGVTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQDHLSEQFGL 253
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKISPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 254 G-HNPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNKKFYDPRVW 332
Cdd:cd00946  241 AdDKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|.
gi 519054599 333 LRKAEEGFSSKLTDICRQLNC 353
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNS 341
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 7-356 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 524.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599    7 LPENVILGDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQG-SIKGA 85
Cdd:TIGR01520   5 VKPGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGaSILGA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   86 VSAALHVHSMAPVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSA 165
Cdd:TIGR01520  85 IAGAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLKRMAK 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  166 MGMTLEIELGVTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQD 245
Cdd:TIGR01520 165 IKMWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKISPNFSIAAAFGNVHGVYKPGNVKLTPDILADGQE 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  246 HLSEQFGL-GHNPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNK 324
Cdd:TIGR01520 245 YVSEKLGLpAAKPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPDKPNK 324

                         330       340       350
                  ....*....|....*....|....*....|..
gi 519054599  325 KFYDPRVWLRKAEEGFSSKLTDICRQLNCESV 356
Cdd:TIGR01520 325 KFYDPRVWLREGEKSMKARVEKACQELNNINV 356
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 19-354 1.13e-106

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 313.95  E-value: 1.13e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  19 ETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGgksvgnsnhqgsikgAVSAALHVHSMAPV 98
Cdd:COG0191    7 ELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAG---------------LEYLAAMVRAAAEE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  99 YGANVMLHTDHAArkllpwidglleaGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTG 178
Cdd:COG0191   72 ASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 179 GEEDGVDNTgiDSSRLYTQPSEVAYAYEKlsqiSDKFTIAASFGNVHGVYsPGNVTLRPEILRNSQDHLseqfglghnPV 258
Cdd:COG0191  139 GEEDGVDVD--DAEALYTDPEEAAEFVEE----TGVDALAVAIGTVHGVY-KGEPKLDFDRLKEIREAV---------PV 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 259 NFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRkgylqaqignpegrdvPNKkfYDPRVWLRKAEE 338
Cdd:COG0191  203 PLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAEN----------------PDK--YDPRKYLKPARE 264

                        330
                 ....*....|....*.
gi 519054599 339 GFSSKLTDICRQLNCE 354
Cdd:COG0191  265 AMKEVVKEKIRLFGSA 280
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
19-354 6.61e-104

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 306.65  E-value: 6.61e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   19 ETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGksvgnsnhqgsikGAVSAALHVHSMAPV 98
Cdd:pfam01116   5 ELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAG-------------GAEALAALVRAAAEA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   99 YGANVMLHTDHAARkllpwIDGLLEAGEEyyrqhgkpLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTG 178
Cdd:pfam01116  72 AGVPVALHLDHGAS-----FELIKEAIEA--------GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIG 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  179 GEEDGVdntgIDSSRLYTQPSEVAYAYEKLSqisdKFTIAASFGNVHGVYSPGNVtLRPEILRNSQDHLseqfglghnPV 258
Cdd:pfam01116 139 GEEDGV----VVDEKLYTDPEEAAEFVEATG----VDALAVAIGNVHGVYKPGPK-LDFDRLKEIQEAV---------PV 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  259 NFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDrkgylqaqignpegrdvpnkkfYDPRVWLRKAEE 338
Cdd:pfam01116 201 PLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPN----------------------KDPRKYLRPAEE 258

                         330
                  ....*....|....*.
gi 519054599  339 GFSSKLTDICRQLNCE 354
Cdd:pfam01116 259 AMKEVVKEKIRLFGSA 274
 
Name Accession Description Interval E-value
PRK09197 PRK09197
fructose-bisphosphate aldolase; Provisional
 11-353 0e+00

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 236406  Cd Length: 350  Bit Score: 619.12  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  11 VILGDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQGSIKGAVSAAL 90
Cdd:PRK09197   3 VATGEDYQEMFDRAKENGFALPAVNVVGTDSINAVLEGAAEAKSPVIIQFSNGGAAFIAGKGVKDDGQGAAVLGAIAGAK 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  91 HVHSMAPVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTL 170
Cdd:PRK09197  83 HVHEVAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAAGGKPLFSSHMIDLSEEPLEENIEICSKYLERMAKAGMTL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 171 EIELGVTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQDHLSEQ 250
Cdd:PRK09197 163 EIELGVTGGEEDGVDNSHEDNSKLYTQPEDVLYAYEALGKISGRFTIAASFGNVHGVYKPGNVKLRPEILKDSQEYVSKK 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 251 FGLGHNPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNKKFYDPR 330
Cdd:PRK09197 243 FGLPAKPFDFVFHGGSGSTLEEIREAVSYGVVKMNIDTDTQWAFWRGVLDYYFKNYDYLQGQVGNPEGEDKPNKKYYDPR 322

                        330       340
                 ....*....|....*....|...
gi 519054599 331 VWLRKAEEGFSSKLTDICRQLNC 353
Cdd:PRK09197 323 VWLRAAEASMAARLEEAFEDLNS 345
FBP_aldolase_IIA cd00946
Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the ...
 14-353 0e+00

Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is homodimeric and used in gluconeogenesis and glycolysis. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238476  Cd Length: 345  Bit Score: 578.17  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  14 GDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQGSIKGAVSAALHVH 93
Cdd:cd00946    1 GDDVLKLFDYAKENGFAIPAVNCTSSSTINAVLEAARDAKSPIIIQFSNGGAAFYAGKGLKNEKQKASIAGAIAAAHHVR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  94 SMAPVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIE 173
Cdd:cd00946   81 SMAEHYGVPVVLHTDHCAKKLLPWFDGLLEADEEYFKQHGEPLFSSHMLDLSEEPLEENIEICKKYLERMAKINMWLEME 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 174 LGVTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQDHLSEQFGL 253
Cdd:cd00946  161 IGITGGEEDGVDNSGVDNAELYTQPEDVWYVYEALSKISPNFSIAAAFGNVHGVYKPGNVKLQPEILGEHQDYVREKLGL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 254 G-HNPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNKKFYDPRVW 332
Cdd:cd00946  241 AdDKPLYFVFHGGSGSTKEEIREAISYGVVKMNIDTDTQWAYWEGVRNYYLKNEDYLQGQIGNPEGPDKPNKKYYDPRVW 320

                        330       340
                 ....*....|....*....|.
gi 519054599 333 LRKAEEGFSSKLTDICRQLNC 353
Cdd:cd00946  321 LREGEKSMVARVKKAFEDLNS 341
FruBisAldo_II_A TIGR01520
fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are ...
 7-356 0e+00

fructose-bisphosphate aldolase, class II, yeast/E. coli subtype; Members of this family are class II examples of the glycolytic enzyme fructose-bisphosphate aldolase (FBA). This model represents one of two deeply split, architecturally distinct clades of the family that includes class II fructose-bisphosphate aldolases, tagatose-bisphosphate aldolases, and related uncharacterized proteins. This family is well-conserved and includes characterized FBA from Saccharomyces cerevisiae, Escherichia coli, and Corynebacterium glutamicum. Proteins outside the scope of this model may also be designated as class II fructose-bisphosphate aldolases, but are well separated in an alignment-based phylogenetic tree. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 130583  Cd Length: 357  Bit Score: 524.00  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599    7 LPENVILGDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQG-SIKGA 85
Cdd:TIGR01520   5 VKPGVITGDDVHKLFQYAKENNFAIPAINCTSSSTINAALEAAADVKSPIIIQFSNGGAAFIAGKGVKDEVPQGaSILGA 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   86 VSAALHVHSMAPVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSA 165
Cdd:TIGR01520  85 IAGAHHVHSIAEHYGVPVVLHTDHCAKKLLPWVDGLLEAGEKYFSAHGKPLFSSHMIDLSEEPIEENIEICVKYLKRMAK 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  166 MGMTLEIELGVTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQD 245
Cdd:TIGR01520 165 IKMWLEIEIGITGGEEDGVDNSHMDAEALYTQPEDVYYAYEELSKISPNFSIAAAFGNVHGVYKPGNVKLTPDILADGQE 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  246 HLSEQFGL-GHNPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNK 324
Cdd:TIGR01520 245 YVSEKLGLpAAKPLFFVFHGGSGSTKQEIKEALSYGVVKMNIDTDTQWAYWEGILNYYKNNEDYLQGQLGNPKGPDKPNK 324

                         330       340       350
                  ....*....|....*....|....*....|..
gi 519054599  325 KFYDPRVWLRKAEEGFSSKLTDICRQLNCESV 356
Cdd:TIGR01520 325 KFYDPRVWLREGEKSMKARVEKACQELNNINV 356
FTBP_aldolase_II cd00453
Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1, ...
 17-352 1.21e-135

Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to yield fructose-1,6-bisphosphate. TBP-aldolase is tetrameric and produces tagarose-1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. Although structurally similar, the class I aldolases use a different mechanism and are believed to have an independent evolutionary origin.


Pssm-ID: 238255  Cd Length: 340  Bit Score: 389.94  E-value: 1.21e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  17 VSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSNHQGS-IKGAVSAALHVHSM 95
Cdd:cd00453    1 VQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAaILGAISGAHHVHQM 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  96 APVYGANVMLHTDHAARKLLPWIDGLLEAGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELG 175
Cdd:cd00453   81 AEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSKYLERMSKIGMTLEIELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 176 VTGGEEDGVDNTGIDSSRLYTQPSEVAYAYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQDHLSEQFGLGH 255
Cdd:cd00453  161 CTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFTIAASFGNVHGVYKKGNVVLTPTILRDSQEYVSKKHNLPH 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 256 NPVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRDVPNKKFYDPRVWLRK 335
Cdd:cd00453  241 NSLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVWLRA 320

                        330
                 ....*....|....*..
gi 519054599 336 AEEGFSSKLTDICRQLN 352
Cdd:cd00453  321 GQTSMIARLEKAFQELN 337
cbbA TIGR00167
ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model ...
 12-354 3.66e-112

ketose-bisphosphate aldolase; This model is under revision. Proteins found by this model include fructose-bisphosphate and tagatose-bisphosphate aldolase. [Energy metabolism, Glycolysis/gluconeogenesis]


Pssm-ID: 272938  Cd Length: 288  Bit Score: 328.12  E-value: 3.66e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   12 ILGDAVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKsvgnsnhqgsikGAVSAALH 91
Cdd:TIGR00167   1 MMLVDVKELLQDAKEEGYAIPAFNINNLETINAVLEAAAEEKSPVIIQFSNGAAKYIAGL------------GAISAMVK 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   92 VHSMAPVYGANVMLHTDHAArkllpwidglleaGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLE 171
Cdd:TIGR00167  69 AMSEAYPYGVPVALHLDHGA-------------SEEDCAQAVKAGFSSVMIDGSHEPFEENIELTKKVVERAHKMGVSVE 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  172 IELGVTGGEEDGVDntGIDSSRLYTQPSEvayaYEKLSQISDKFTIAASFGNVHGVYSPGNVTLRPEILRNSQDHLSeqf 251
Cdd:TIGR00167 136 AELGTLGGEEDGVS--VADESALYTDPEE----AKEFVKLTGVDSLAAAIGNVHGVYKGEPKGLDFERLEEIQKYVN--- 206

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  252 glghnpVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDrkgylqaqignpegrdvpNKKFYDPRV 331
Cdd:TIGR00167 207 ------LPLVLHGGSGIPDEEIKKAISLGVVKVNIDTELQIAFAAAVRNYYAE------------------NKDYYDPRV 262

                         330       340
                  ....*....|....*....|...
gi 519054599  332 WLRKAEEGFSSKLTDICRQLNCE 354
Cdd:TIGR00167 263 WLRPGEKAMKEVVLEKIKLFGSA 285
Fba COG0191
Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose ...
 19-354 1.13e-106

Fructose/tagatose bisphosphate aldolase [Carbohydrate transport and metabolism]; Fructose/tagatose bisphosphate aldolase is part of the Pathway/BioSystem: Glycolysis


Pssm-ID: 439961  Cd Length: 283  Bit Score: 313.95  E-value: 1.13e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  19 ETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGgksvgnsnhqgsikgAVSAALHVHSMAPV 98
Cdd:COG0191    7 ELLDKAKEGGYAVPAFNVNNLETLQAILEAAEELNSPVILQVSEGAAKYAG---------------LEYLAAMVRAAAEE 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  99 YGANVMLHTDHAArkllpwidglleaGEEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTG 178
Cdd:COG0191   72 ASVPVALHLDHGA-------------SFELIKRAIDAGFTSVMIDGSHLPFEENIAITKEVVEYAHAAGVSVEAELGVVG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 179 GEEDGVDNTgiDSSRLYTQPSEVAYAYEKlsqiSDKFTIAASFGNVHGVYsPGNVTLRPEILRNSQDHLseqfglghnPV 258
Cdd:COG0191  139 GEEDGVDVD--DAEALYTDPEEAAEFVEE----TGVDALAVAIGTVHGVY-KGEPKLDFDRLKEIREAV---------PV 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 259 NFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRkgylqaqignpegrdvPNKkfYDPRVWLRKAEE 338
Cdd:COG0191  203 PLVLHGGSGVPDEEIREAIKLGVAKINIDTDLRLAFTAAVREYLAEN----------------PDK--YDPRKYLKPARE 264

                        330
                 ....*....|....*.
gi 519054599 339 GFSSKLTDICRQLNCE 354
Cdd:COG0191  265 AMKEVVKEKIRLFGSA 280
F_bP_aldolase pfam01116
Fructose-bisphosphate aldolase class-II;
19-354 6.61e-104

Fructose-bisphosphate aldolase class-II;


Pssm-ID: 460071  Cd Length: 276  Bit Score: 306.65  E-value: 6.61e-104
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   19 ETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGksvgnsnhqgsikGAVSAALHVHSMAPV 98
Cdd:pfam01116   5 ELLKKAKEGGYAVPAFNVNNLETVQAILEAAEEAKSPVILQVSPGAAAKYAG-------------GAEALAALVRAAAEA 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   99 YGANVMLHTDHAARkllpwIDGLLEAGEEyyrqhgkpLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTG 178
Cdd:pfam01116  72 AGVPVALHLDHGAS-----FELIKEAIEA--------GFTSVMIDGSHLPFEENIAITKEVVEYAHARGVSVEAELGRIG 138

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  179 GEEDGVdntgIDSSRLYTQPSEVAYAYEKLSqisdKFTIAASFGNVHGVYSPGNVtLRPEILRNSQDHLseqfglghnPV 258
Cdd:pfam01116 139 GEEDGV----VVDEKLYTDPEEAAEFVEATG----VDALAVAIGNVHGVYKPGPK-LDFDRLKEIQEAV---------PV 200

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  259 NFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDrkgylqaqignpegrdvpnkkfYDPRVWLRKAEE 338
Cdd:pfam01116 201 PLVLHGGSGVPDEDIRKAIKLGVCKINIDTDLQLAFTAAVREYPPN----------------------KDPRKYLRPAEE 258

                         330
                  ....*....|....*.
gi 519054599  339 GFSSKLTDICRQLNCE 354
Cdd:pfam01116 259 AMKEVVKEKIRLFGSA 274
TBP_aldolase_IIB cd00947
Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase ...
 24-338 1.22e-45

Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1,6-bisphosphate. There is an absolute requirement for a divalent metal ion, usually zinc, and in addition the enzymes are activated by monovalent cations such as Na+. The type A and type B Class II FBPA's differ in the presence and absence of distinct indels in the sequence that result in differing loop lengths in the structures.


Pssm-ID: 238477  Cd Length: 276  Bit Score: 157.30  E-value: 1.22e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  24 AKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSvgnsnhqgsIKGAVSAALHVHSMapvygaNV 103
Cdd:cd00947    8 AREGGYAVGAFNINNLETLKAILEAAEETRSPVILQISEGAIKYAGLEL---------LVAMVKAAAERASV------PV 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 104 MLHTDHAARkllpwIDGLLEAgeeyyRQHGkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTGGEEDG 183
Cdd:cd00947   73 ALHLDHGSS-----FELIKRA-----IRAG---FSSVMIDGSHLPFEENVAKTKEVVELAHAYGVSVEAELGRIGGEEDG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 184 VDNTGIdssrLYTQPSEvAYAYEKLSQIsDkfTIAASFGNVHGVYSPGNVTLRPEILRNsqdhLSEQFglghnPVNFVFH 263
Cdd:cd00947  140 VVGDEG----LLTDPEE-AEEFVEETGV-D--ALAVAIGTSHGAYKGGEPKLDFDRLKE----IAERV-----NVPLVLH 202

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 519054599 264 GGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDrkgylqaqignpegrdvpNKKFYDPRVWLRKAEE 338
Cdd:cd00947  203 GGSGIPDEQIRKAIKLGVCKININTDLRLAFTAALREYLAE------------------NPKEFDPRKYLAPAIE 259
PRK08610 PRK08610
fructose-bisphosphate aldolase; Reviewed
 16-338 2.38e-27

fructose-bisphosphate aldolase; Reviewed


Pssm-ID: 181501  Cd Length: 286  Bit Score: 108.92  E-value: 2.38e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  16 AVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSvgnsnhqgSIKGAVSAALHVHSM 95
Cdd:PRK08610   5 SMKEMLIDAKENGYAVGQYNLNNLEFTQAILEASQEENAPVILGVSEGAARYMSGFY--------TVVKMVEGLMHDLNI 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  96 ApvygANVMLHTDHAA--RKLLPWIDglleAGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIE 173
Cdd:PRK08610  77 T----IPVAIHLDHGSsfEKCKEAID----AG-----------FTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAE 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 174 LGVTGGEEDGVDNTGIdssrLYTQPSEVayayEKLSQISDKFTIAASFGNVHGVYSPgnvtlRPEILRNSQDHLSEQFGL 253
Cdd:PRK08610 138 LGTVGGQEDDVVADGI----IYADPKEC----QELVEKTGIDALAPALGSVHGPYKG-----EPKLGFKEMEEIGLSTGL 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 254 ghnPVnfVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDrkgylqaqignpegrdvpNKKFYDPRVWL 333
Cdd:PRK08610 205 ---PL--VLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAVRDVLNN------------------DKEVYDPRKYL 261


                 ....*
gi 519054599 334 RKAEE 338
Cdd:PRK08610 262 GPARE 266
gatY PRK09195
tagatose-bisphosphate aldolase; Reviewed
 17-354 4.80e-27

tagatose-bisphosphate aldolase; Reviewed


Pssm-ID: 181690  Cd Length: 284  Bit Score: 107.90  E-value: 4.80e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  17 VSETFAFAKAQR--MALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAfYGGKsvgnsnhqGSIKGAVSAALHVHS 94
Cdd:PRK09195   4 VSTKQMLNNAQRggYAVPAFNIHNLETMQVVVETAAELHSPVIIAGTPGTFS-YAGT--------EYLLAIVSAAAKQYH 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  95 MApvyganVMLHTDHAARklLPWIDGLLEAGeeyYRqhgkplfsSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIEL 174
Cdd:PRK09195  75 HP------LALHLDHHEK--FDDIAQKVRSG---VR--------SVMIDGSHLPFAQNISLVKEVVDFCHRFDVSVEAEL 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 175 GVTGGEEDGVDNTGIDSsrLYTQPSEvAYAYEKLSQISdkfTIAASFGNVHGVYSpGNVTL---RPEILRNSQDhlseqf 251
Cdd:PRK09195 136 GRLGGQEDDLQVDEADA--LYTDPAQ-AREFVEATGID---SLAVAIGTAHGMYK-GEPKLdfdRLENIRQWVN------ 202

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 252 glghnpVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVrefyedrKGYLqaqIGNPEGRdvpnkkfyDPRV 331
Cdd:PRK09195 203 ------IPLVLHGASGLPTKDIQQTIKLGICKVNVATELKIAFSQAL-------KNYL---TEHPEAN--------DPRH 258

                        330       340
                 ....*....|....*....|...
gi 519054599 332 WLRKAEEGFSSKLTDICRQLNCE 354
Cdd:PRK09195 259 YLQPAKSAMKDVVSKVIADCGCE 281
PRK08185 PRK08185
hypothetical protein; Provisional
 19-320 1.03e-26

hypothetical protein; Provisional


Pssm-ID: 181275  Cd Length: 283  Bit Score: 107.12  E-value: 1.03e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  19 ETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNsnhqgsikgaVSAALHvHSMAPV 98
Cdd:PRK08185   3 ELLKVAKEHQFAVGAFNVADSCFLRAVVEEAEANNAPAIIAIHPNELDFLGDNFFAY----------VRERAK-RSPVPF 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  99 yganvMLHTDHAARkllpwIDGLLEAgeeyyRQHGkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGvTG 178
Cdd:PRK08185  72 -----VIHLDHGAT-----IEDVMRA-----IRCG---FTSVMIDGSLLPYEENVALTKEVVELAHKVGVSVEGELG-TI 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 179 GEEDGVDNTGIDSSrLYTQPSEvAYAYEKLSQISdkfTIAASFGNVHGVYSPGnvtLRPEILRNSQDHLSEQFGlghnpV 258
Cdd:PRK08185 133 GNTGTSIEGGVSEI-IYTDPEQ-AEDFVSRTGVD---TLAVAIGTAHGIYPKD---KKPELQMDLLKEINERVD-----I 199

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 519054599 259 NFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKGYLQAQIGNPEGRD 320
Cdd:PRK08185 200 PLVLHGGSANPDAEIAESVQLGVGKINISSDMKYAFFKKVREILSDNPSLYEPNQIYPSAIE 261
PRK07709 PRK07709
fructose-bisphosphate aldolase; Provisional
 16-320 1.74e-26

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 169068  Cd Length: 285  Bit Score: 106.68  E-value: 1.74e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  16 AVSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGG-KSVGNSnhqgsIKGAVSaalHVHS 94
Cdd:PRK07709   5 SMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGfKTVVAM-----VKALIE---EMNI 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  95 MAPVyganvMLHTDHAA--RKLLPWIDglleAGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEI 172
Cdd:PRK07709  77 TVPV-----AIHLDHGSsfEKCKEAID----AG-----------FTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEA 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 173 ELGVTGGEEDGVDNTGIdssrLYTQPSEVayayEKLSQISDKFTIAASFGNVHGVYSPgnvtlRPEILRNSQDHLSEQFG 252
Cdd:PRK07709 137 ELGTVGGQEDDVIAEGV----IYADPAEC----KHLVEATGIDCLAPALGSVHGPYKG-----EPNLGFAEMEQVRDFTG 203

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 519054599 253 lghnpVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVRE-FYEDRKGYLQAQIGNPeGRD 320
Cdd:PRK07709 204 -----VPLVLHGGTGIPTADIEKAISLGTSKINVNTENQIEFTKAVREvLNKDQEVYDPRKFIGP-GRD 266
PRK12857 PRK12857
class II fructose-1,6-bisphosphate aldolase;
17-338 1.77e-26

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 237235  Cd Length: 284  Bit Score: 106.35  E-value: 1.77e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  17 VSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLShggaafyggksvgnsnhQGSIKGAvsAALHVHSMA 96
Cdd:PRK12857   6 VAELLKKAEKGGYAVGAFNCNNMEIVQAIVAAAEAEKSPVIIQAS-----------------QGAIKYA--GIEYISAMV 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  97 PVYGAN----VMLHTDHAARklLPWIDGLLEAGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEI 172
Cdd:PRK12857  67 RTAAEKasvpVALHLDHGTD--FEQVMKCIRNG-----------FTSVMIDGSKLPLEENIALTKKVVEIAHAVGVSVEA 133

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 173 ELGVTGGEEDgvDNTGIDSSRLYTQPSEVAYAYEKLSQISdkftIAASFGNVHGVYSpgnvtLRPEIlrnSQDHLSEQFG 252
Cdd:PRK12857 134 ELGKIGGTED--DITVDEREAAMTDPEEARRFVEETGVDA----LAIAIGTAHGPYK-----GEPKL---DFDRLAKIKE 199

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 253 LGHNPVnfVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDrkgylqaqignpegrdvpNKKFYDPRVW 332
Cdd:PRK12857 200 LVNIPI--VLHGSSGVPDEAIRKAISLGVRKVNIDTNIREAFVARLREVLEK------------------NPDEIDPRKI 259


                 ....*.
gi 519054599 333 LRKAEE 338
Cdd:PRK12857 260 LGPARE 265
gatY PRK12737
tagatose-bisphosphate aldolase subunit GatY;
25-306 5.26e-26

tagatose-bisphosphate aldolase subunit GatY;


Pssm-ID: 183710  Cd Length: 284  Bit Score: 105.16  E-value: 5.26e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  25 KAQR--MALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGgksvgnsnhQGSIKGAVSAALHVHSMApvygan 102
Cdd:PRK12737  12 KAQAegYAVPAFNIHNLETLQVVVETAAELRSPVILAGTPGTFSYAG---------TDYIVAIAEVAARKYNIP------ 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 103 VMLHTDHaaRKLLPWIDGLLEAGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTGGEED 182
Cdd:PRK12737  77 LALHLDH--HEDLDDIKKKVRAG-----------IRSVMIDGSHLSFEENIAIVKEVVEFCHRYDASVEAELGRLGGQED 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 183 GVDNTGIDSsrLYTQPSEvAYAYEKLSQISdkfTIAASFGNVHGVYSpGNVTL---RPEILRNSQDhlseqfglghnpVN 259
Cdd:PRK12737 144 DLVVDEKDA--MYTNPDA-AAEFVERTGID---SLAVAIGTAHGLYK-GEPKLdfeRLAEIREKVS------------IP 204

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 519054599 260 FVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVRE-FYEDRK 306
Cdd:PRK12737 205 LVLHGASGVPDEDVKKAISLGICKVNVATELKIAFSDAVKKyFYENPK 252
gatY PRK07998
class II aldolase;
24-304 2.38e-21

class II aldolase;


Pssm-ID: 181192  Cd Length: 283  Bit Score: 92.52  E-value: 2.38e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  24 AKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNSnhqgsikgavsaalhVHSMAPVYGANV 103
Cdd:PRK07998  13 IQEKHVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEI---------------VKRHADKMDVPV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 104 MLHTDHAarKLLpwidglleageEYYRQHGKPLFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTGGEEDG 183
Cdd:PRK07998  78 SLHLDHG--KTF-----------EDVKQAVRAGFTSVMIDGAALPFEENIAFTKEAVDFAKSYGVPVEAELGAILGKEDD 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 184 vDNTGIDSsrlYTQPSEVAYAYEKLSqiSDkfTIAASFGNVHGVyspgnvTLRPEIlrnSQDHLSEQFGLghNPVNFVFH 263
Cdd:PRK07998 145 -HVSEADC---KTEPEKVKDFVERTG--CD--MLAVSIGNVHGL------EDIPRI---DIPLLKRIAEV--SPVPLVIH 205

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 519054599 264 GGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYED 304
Cdd:PRK07998 206 GGSGIPPEILRSFVNYKVAKVNIASDLRKAFITTVGKAYVN 246
PRK07315 PRK07315
fructose-bisphosphate aldolase; Provisional
 23-334 4.56e-21

fructose-bisphosphate aldolase; Provisional


Pssm-ID: 180926  Cd Length: 293  Bit Score: 91.87  E-value: 4.56e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  23 FAKAQR---MALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGGKSVGNsnhqgsikgAVSAALhVHSMAPVy 99
Cdd:PRK07315   9 FVQAARdngYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVCK---------NLIENL-VESMGIT- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 100 gANVMLHTDHAArkllpwIDGLLEAGEEYYrqhgkplfSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTGG 179
Cdd:PRK07315  78 -VPVAIHLDHGH------YEDALECIEVGY--------TSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGG 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 180 EEDGVDNTGidssrlYTQPSEVAYAyekLSQISDKFtIAASFGNVHGVYspgnvtlrPEILRN-SQDHLsEQFGLGHNPV 258
Cdd:PRK07315 143 EEDGIIGKG------ELAPIEDAKA---MVETGIDF-LAAGIGNIHGPY--------PENWEGlDLDHL-EKLTEAVPGF 203

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 519054599 259 NFVFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRKgylqaqiGNPEGRDvpNKKFYDPRVWLR 334
Cdd:PRK07315 204 PIVLHGGSGIPDDQIQEAIKLGVAKVNVNTECQIAFANATRKFARDYE-------ANEAEYD--KKKLFDPRKFLA 270
PRK06806 PRK06806
class II aldolase;
69-300 4.97e-21

class II aldolase;


Pssm-ID: 180705  Cd Length: 281  Bit Score: 91.36  E-value: 4.97e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  69 GGKSVGNSNhqgSIKGAVSAALHVHS------------------MAPVYGA-------NVMLHTDHAarKLLPWIDGLLE 123
Cdd:PRK06806  21 GAFSVANME---MVMGAIKAAEELNSpiilqiaevrlnhsplhlIGPLMVAaakqakvPVAVHFDHG--MTFEKIKEALE 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 124 AGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTGGEEDGVDNTGIdssrLYTQPSEVay 203
Cdd:PRK06806  96 IG-----------FTSVMFDGSHLPLEENIQKTKEIVELAKQYGATVEAEIGRVGGSEDGSEDIEM----LLTSTTEA-- 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 204 ayEKLSQISDKFTIAASFGNVHGVYsPGNVTLRPEILRNSQDHLseqfglghnPVNFVFHGGSGSSAEDIAAGIDYGVIK 283
Cdd:PRK06806 159 --KRFAEETDVDALAVAIGNAHGMY-NGDPNLRFDRLQEINDVV---------HIPLVLHGGSGISPEDFKKCIQHGIRK 226

                        250
                 ....*....|....*..
gi 519054599 284 VNVDTdlqwAYWNGVRE 300
Cdd:PRK06806 227 INVAT----ATFNSVIT 239
kbaY PRK12738
tagatose-bisphosphate aldolase subunit KbaY;
24-352 1.11e-19

tagatose-bisphosphate aldolase subunit KbaY;


Pssm-ID: 183711  Cd Length: 286  Bit Score: 87.78  E-value: 1.11e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  24 AKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIqlshggaafygGKSVGNSNHQGSIKgaVSAALHVHSMApvYGANV 103
Cdd:PRK12738  13 AQANGYAVPAFNIHNAETIQAILEVCSEMRSPVIL-----------AGTPGTFKHIALEE--IYALCSAYSTT--YNMPL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 104 MLHTDHaaRKLLPWIDGLLEAGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTGGEEDG 183
Cdd:PRK12738  78 ALHLDH--HESLDDIRRKVHAG-----------VRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDD 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 184 VDntgIDS-SRLYTQPSEvAYAYEKLSQISdkfTIAASFGNVHGVYspgnvTLRPEIlrnSQDHLSEQFGLGHNPVnfVF 262
Cdd:PRK12738 145 MS---VDAeSAFLTDPQE-AKRFVELTGVD---SLAVAIGTAHGLY-----SKTPKI---DFQRLAEIREVVDVPL--VL 207

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 263 HGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDrkgylqaqigNPEGRDvpnKKFYdPRVWLRKAEEGFSS 342
Cdd:PRK12738 208 HGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAE----------NPQGND---PRYY-MRVGMDAMKEVVRN 273

                        330
                 ....*....|
gi 519054599 343 KLTdICRQLN 352
Cdd:PRK12738 274 KIN-VCGSAN 282
PLN02858 PLN02858
fructose-bisphosphate aldolase
 30-294 1.98e-19

fructose-bisphosphate aldolase


Pssm-ID: 215463 [Multi-domain]  Cd Length: 1378  Bit Score: 89.91  E-value: 1.98e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599   30 ALPAVNITTSSTANSVMAVAAELNAPVIIQLsHGGAAFYGGKSVgnsnhqgsIKGAVSAAlhVHSMAPVyganvMLHTDH 109
Cdd:PLN02858 1115 AVGAFNVYNLEGIEAVVAAAEAEKSPAILQV-HPGALKQGGIPL--------VSCCIAAA--EQASVPI-----TVHFDH 1178

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  110 AARK--LLPwidgLLEAGeeyyrqhgkplFSSHMIDLSEEPLEDNIEtcceYLKRMSAM----GMTLEIELGVTGGEEDG 183
Cdd:PLN02858 1179 GTSKheLLE----ALELG-----------FDSVMVDGSHLSFTENIS----YTKSISSLahskGLMVEAELGRLSGTEDG 1239

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  184 VDNTGIDSsrlytQPSEVAYAYEKLSQISDKfTIAASFGNVHGVYSPGNVTLRPEILRNSQDhLSEQFGlghnpVNFVFH 263
Cdd:PLN02858 1240 LTVEEYEA-----KLTDVDQAKEFIDETGID-ALAVCIGNVHGKYPASGPNLRLDLLKELRA-LSSKKG-----VLLVLH 1307

                         250       260       270
                  ....*....|....*....|....*....|.
gi 519054599  264 GGSGSSAEDIAAGIDYGVIKVNVDTDLQWAY 294
Cdd:PLN02858 1308 GASGLPESLIKECIENGVRKFNVNTEVRTAY 1338
PRK09196 PRK09196
fructose-bisphosphate aldolase class II;
31-350 1.81e-18

fructose-bisphosphate aldolase class II;


Pssm-ID: 181691  Cd Length: 347  Bit Score: 85.01  E-value: 1.81e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  31 LPAVNITTSSTANSVMAVAAELNAPVIIQLShGGAAFYGGKSVgnsnhqgsIKGAVSAALHVHSMAPVyganVMlHTDHa 110
Cdd:PRK09196  20 VPAFNVNNLEQVQAIMEAADETDSPVILQAS-AGARKYAGEPF--------LRHLILAAVEEYPHIPV----VM-HQDH- 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 111 arkllpwidGLLEAGEEYYRQHGkplFSSHMIDLSEEP-------LEDNIETCCEYLKRMSAMGMTLEIELGV------- 176
Cdd:PRK09196  85 ---------GNSPATCQRAIQLG---FTSVMMDGSLKAdgktpasYEYNVDVTRKVVEMAHACGVSVEGELGClgsletg 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 177 TGGEEDGVDNTG-IDSSRLYTQPSEvAYAYEKLSQIsDKFTIAasFGNVHGVYspgNVTLRP--EILRNSQ--------- 244
Cdd:PRK09196 153 MGGEEDGHGAEGkLSHDQLLTDPEE-AADFVKKTQV-DALAIA--IGTSHGAY---KFTRKPtgDVLAIDRikeiharlp 225

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 245 -DHLseqfglghnpvnfVFHGGS---------------------GSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFY 302
Cdd:PRK09196 226 nTHL-------------VMHGSSsvpqelldiineyggdmpetyGVPVEEIQEGIKHGVRKVNIDTDLRLAMTGAIRRFL 292

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*...
gi 519054599 303 EDrkgylqaqignpegrdvpNKKFYDPRVWLRKAEEGfsskLTDICRQ 350
Cdd:PRK09196 293 AE------------------NPSEFDPRKYLKPAMEA----MKKICKA 318
PRK07084 PRK07084
class II fructose-1,6-bisphosphate aldolase;
19-338 3.65e-15

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180829  Cd Length: 321  Bit Score: 75.15  E-value: 3.65e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  19 ETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLShGGAAFYGGKSVGNSNHQGsikgAVSAALHVHSMAPV 98
Cdd:PRK07084  14 EMFAKAVKGGYAIPAYNFNNMEQLQAIIQACVETKSPVILQVS-KGARKYANATLLRYMAQG----AVEYAKELGCPIPI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  99 yganvMLHTDHAARKLLpwIDGLLEAGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGVTG 178
Cdd:PRK07084  89 -----VLHLDHGDSFEL--CKDCIDSG-----------FSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLA 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 179 GEEDGVdntgIDSSRLYTQPSEVAYAYEKLSQISdkftIAASFGNVHGVY--SPGNV--TLRPEILRNSQDHLSeqfGLg 254
Cdd:PRK07084 151 GVEDEV----SAEHHTYTQPEEVEDFVKKTGVDS----LAISIGTSHGAYkfKPGQCppPLRFDILEEIEKRIP---GF- 218

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 255 hnPVnfVFHGGSGSSAEDIAAGIDYG---------------------VIKVNVDTDLQWAYWNGVREFYEDrkgylqaqi 313
Cdd:PRK07084 219 --PI--VLHGSSSVPQEYVKTINEYGgklkdaigipeeqlrkaaksaVCKINIDSDGRLAMTAAIRKVFDE--------- 285

                        330       340
                 ....*....|....*....|....*
gi 519054599 314 gNPEgrdvpnkkFYDPRVWLRKAEE 338
Cdd:PRK07084 286 -KPE--------EFDPRKYLGPARD 301
PRK13399 PRK13399
fructose-bisphosphate aldolase class II;
30-350 4.97e-15

fructose-bisphosphate aldolase class II;


Pssm-ID: 184029  Cd Length: 347  Bit Score: 75.20  E-value: 4.97e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  30 ALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGgksvgnsnhQGSIKGAVSAALHVHSMAPvyganVMLHTDH 109
Cdd:PRK13399  19 GVPAFNVNNMEQILAIMEAAEATDSPVILQASRGARKYAG---------DAMLRHMVLAAAEMYPDIP-----ICLHQDH 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 110 AARkllpwidgllEAGEEYYRQHGkplFSSHMIDLSEEP-------LEDNIETCCEYLKRMSAMGMTLEIELGV------ 176
Cdd:PRK13399  85 GNS----------PATCQSAIRSG---FTSVMMDGSLLAdgktpasYDYNVDVTRRVTEMAHAVGVSVEGELGClgslet 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 177 -TGGEEDGVDNTG-IDSSRLYTQPSEVAyayeKLSQISDKFTIAASFGNVHGVYspgNVTLRP--EIL---RNSQDHlsE 249
Cdd:PRK13399 152 gEAGEEDGVGAEGkLSHDQMLTDPDQAV----DFVQRTGVDALAIAIGTSHGAY---KFTRKPdgDILaidRIEEIH--A 222

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 250 QFGLGHnpvnFVFHGGS---------------------GSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVRefyedrkgy 308
Cdd:PRK13399 223 RLPNTH----LVMHGSSsvpqelqeiinayggkmketyGVPVEEIQRGIKHGVRKVNIDTDIRLAMTGAIR--------- 289

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|..
gi 519054599 309 lQAQIGNPEGrdvpnkkfYDPRVWLRKAEEGfsskLTDICRQ 350
Cdd:PRK13399 290 -KVLAEHPSE--------FDPRKALKPAMKA----MTALCKQ 318
PRK06801 PRK06801
ketose 1,6-bisphosphate aldolase;
17-288 4.70e-13

ketose 1,6-bisphosphate aldolase;


Pssm-ID: 180701  Cd Length: 286  Bit Score: 68.62  E-value: 4.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  17 VSETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLshggaAFYGGKSVGNSNHQGSIKgaVSAALHvhsma 96
Cdd:PRK06801   6 LANGLAHARKHGYALGAFNVLDSHFLRALFAAAKQERSPFIINI-----AEVHFKYISLESLVEAVK--FEAARH----- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  97 pvyGANVMLHTDHaarkllpwidGL-LEAGEEYYRQHgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELG 175
Cdd:PRK06801  74 ---DIPVVLNLDH----------GLhFEAVVRALRLG----FSSVMFDGSTLEYEENVRQTREVVKMCHAVGVSVEAELG 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 176 VTGGEEDGVDNTGIDSSrLYTQPsEVAYAYEKLSQISdkfTIAASFGNVHGVYSpGNVTLRPEILrnsqDHLSEQFGlgh 255
Cdd:PRK06801 137 AVGGDEGGALYGEADSA-KFTDP-QLARDFVDRTGID---ALAVAIGNAHGKYK-GEPKLDFARL----AAIHQQTG--- 203

                        250       260       270
                 ....*....|....*....|....*....|...
gi 519054599 256 npVNFVFHGGSGSSAEDIAAGIDYGVIKVNVDT 288
Cdd:PRK06801 204 --LPLVLHGGSGISDADFRRAIELGIHKINFYT 234
PRK05835 PRK05835
class II fructose-1,6-bisphosphate aldolase;
18-306 3.34e-10

class II fructose-1,6-bisphosphate aldolase;


Pssm-ID: 180280 [Multi-domain]  Cd Length: 307  Bit Score: 60.37  E-value: 3.34e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  18 SETFAFAKAQRMALPAVNITTSSTANSVMAVAAELNAPVIIQLSHGGAAFYGgksvgnsnhqgsIKGAVSAalhVHSMAP 97
Cdd:PRK05835   6 NEILLKAHKEGYGVGAFNFVNFEMLNAIFEAGNEENSPLFIQASEGAIKYMG------------IDMAVGM---VKIMCE 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599  98 VY-GANVMLHTDHAARklLPWIDGLLEAGeeyyrqhgkplFSSHMIDLSEEPLEDNIETCCEYLKRMSAMGMTLEIELGV 176
Cdd:PRK05835  71 RYpHIPVALHLDHGTT--FESCEKAVKAG-----------FTSVMIDASHHAFEENLELTSKVVKMAHNAGVSVEAELGR 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 519054599 177 TGGEEdgvDNTGIDSS-RLYTQPSEvAYAYEKLSQISdkfTIAASFGNVHGVYS-PGNVTLRPEILRNSQ---------- 244
Cdd:PRK05835 138 LMGIE---DNISVDEKdAVLVNPKE-AEQFVKESQVD---YLAPAIGTSHGAFKfKGEPKLDFERLQEVKrltniplvlh 210

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 519054599 245 ------DHLSEQF-GLGHNpvnfvFHGGSGSSAEDIAAGIDYGVIKVNVDTDLQWAYWNGVREFYEDRK 306
Cdd:PRK05835 211 gasaipDDVRKSYlDAGGD-----LKGSKGVPFEFLQESVKGGINKVNTDTDLRIAFIAEVRKVANEDK 274
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH