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Conserved domains on  [gi|520907735|ref|WP_020327745|]
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MULTISPECIES: cell envelope integrity protein TolA [Vibrio]

Protein Classification

cell envelope integrity protein TolA( domain architecture ID 11494998)

cell envelope integrity protein TolA is part of the Tol-Pal system that plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity

Gene Ontology:  GO:0016020

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 12-356 3.58e-42

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


:

Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 150.00  E-value: 3.58e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   12 KKPLAISVGLHVALVAALLWGTDFTMSKPETSGH--MVEAVVIDPNLVKQQAQQIRSQREAAAKQEQERLDKLRRESEQL 89
Cdd:TIGR02794   1 RRAFLLSLLLHILLLGLLILGSLYHSVKPEPGGGaeIIQAVLVDPGAVAQQANRIQQQKKPAAKKEQERQKKLEQQAEEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   90 EKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQEQERAAKAEAERKLKEEA-------AKKAEAE 162
Cdd:TIGR02794  81 EKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEeaakqaeEEAKAKA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  163 RVAKEAAAAKAEQERVAREKAAQEAQEKARKErEAAAKAEQERIAKEKAAKAAAEKARlekERAERAERERKEQEAALNN 242
Cdd:TIGR02794 161 AAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAE-EAKAKAEAAKAKAAAEAAAKAEAEA---AAAAAAEAERKADEAELGD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  243 IFAGLETESQNNSV-ARSQHVTSEAQRWGAIYTQLIQQNLLLEDSFKGKQCRVNLRLIPTGTgaiVGDLRILDGDSRLCA 321
Cdd:TIGR02794 237 IFGLASGSNAEKQGgARGAAAGSEVDKYAAIIQQAIQQNLYDDPSFRGKTCRLRIRLAPDGT---LLSVTKSSGDPALCQ 313

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 520907735  322 ATKRAVAQVGTFPLPKKDesDVIEKLKNINLTVVP 356
Cdd:TIGR02794 314 AALAAVAKAAKLPMPPSD--PVYEEFKNINLTFKP 346
 
Name Accession Description Interval E-value
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 12-356 3.58e-42

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 150.00  E-value: 3.58e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   12 KKPLAISVGLHVALVAALLWGTDFTMSKPETSGH--MVEAVVIDPNLVKQQAQQIRSQREAAAKQEQERLDKLRRESEQL 89
Cdd:TIGR02794   1 RRAFLLSLLLHILLLGLLILGSLYHSVKPEPGGGaeIIQAVLVDPGAVAQQANRIQQQKKPAAKKEQERQKKLEQQAEEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   90 EKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQEQERAAKAEAERKLKEEA-------AKKAEAE 162
Cdd:TIGR02794  81 EKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEeaakqaeEEAKAKA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  163 RVAKEAAAAKAEQERVAREKAAQEAQEKARKErEAAAKAEQERIAKEKAAKAAAEKARlekERAERAERERKEQEAALNN 242
Cdd:TIGR02794 161 AAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAE-EAKAKAEAAKAKAAAEAAAKAEAEA---AAAAAAEAERKADEAELGD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  243 IFAGLETESQNNSV-ARSQHVTSEAQRWGAIYTQLIQQNLLLEDSFKGKQCRVNLRLIPTGTgaiVGDLRILDGDSRLCA 321
Cdd:TIGR02794 237 IFGLASGSNAEKQGgARGAAAGSEVDKYAAIIQQAIQQNLYDDPSFRGKTCRLRIRLAPDGT---LLSVTKSSGDPALCQ 313

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 520907735  322 ATKRAVAQVGTFPLPKKDesDVIEKLKNINLTVVP 356
Cdd:TIGR02794 314 AALAAVAKAAKLPMPPSD--PVYEEFKNINLTFKP 346
TolA pfam06519
TolA C-terminal; This family consists of several bacterial TolA proteins as well as two ...
 257-354 1.02e-32

TolA C-terminal; This family consists of several bacterial TolA proteins as well as two eukaryotic proteins of unknown function. Tol proteins are involved in the translocation of group A colicins. Colicins are bacterial protein toxins, which are active against Escherichia coli and other related species (See pfam01024). TolA is anchored to the cytoplasmic membrane by a single membrane spanning segment near the N-terminus, leaving most of the protein exposed to the periplasm.


Pssm-ID: 399492 [Multi-domain]  Cd Length: 94  Bit Score: 117.53  E-value: 1.02e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  257 ARSQHVTSEAQRWGAIYTQLIQQNLLLEDSFKGKQCRVNLRLIPTGTgaiVGDLRILDGDSRLCAATKRAVAQVGTFPLP 336
Cdd:pfam06519   2 AGSGASGAEVDRYAGQIKQAIQSRFLKDDSFAGKTCRVRIKLAPDGT---LISVKVEGGDPALCQAAKAAVAKTAKIPKP 78

                          90
                  ....*....|....*...
gi 520907735  337 KKDesDVIEKLKNINLTV 354
Cdd:pfam06519  79 PSQ--DVYEKFKNINLDF 94
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 1-349 2.03e-17

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 82.55  E-value: 2.03e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   1 MKDQKSKKNDFKKPLAISVGLHVALVAALLWGT---DFTMSKPETSGHMVEAVVIDPNLVKQQAQQIRSQREAAAKQEQE 77
Cdd:PRK09510   1 MSKATEQNDKLKRAIIISVVLHIILFALLIWSSfdeNIEASGGGGGGSVIDAVMVDPGAVVEQYNRQQQQQKSAKRAEEQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  78 RLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQEQERA-AKAEAERKLKEEAA 156
Cdd:PRK09510  81 RKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAkAKAEAEAKRAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 157 KKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQE---------------RIAKEKAAKAAAEKARL 221
Cdd:PRK09510 161 KKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKkkaaaeakkkaaaeaKAAAAKAAAEAKAAAEK 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 222 EKERAERAERERKEQEAALNNIFAGLET----------ESQNNSVARSQHVTSEAQRWGAIYTQL-------IQQNLLLE 284
Cdd:PRK09510 241 AAAAKAAEKAAAAKAAAEVDDLFGGLDSgknapktgggAKGNGAQGAGAGNGKKGGASGADIDQYagqiksaIQSKFYDA 320

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 520907735 285 DSFKGKQCRVNLRLIPTGTgaiVGDLRILDGDSRLCAAtkrAVAQVGTFPLPKKDESDVIEKLKN 349
Cdd:PRK09510 321 SSYAGKTCTLRIKLAPDGT---LLDIKKEGGDPALCQA---ALAAAKTAKIPKPPSQEVYEKFKN 379
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 58-252 2.53e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 2.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  58 KQQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQ 137
Cdd:COG1196  297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 138 EQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERIAKEKAAKAAAE 217
Cdd:COG1196  377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 520907735 218 KARLEKERAERAERERKEQEAALNNIFAGLETESQ 252
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
 
Name Accession Description Interval E-value
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 12-356 3.58e-42

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 150.00  E-value: 3.58e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   12 KKPLAISVGLHVALVAALLWGTDFTMSKPETSGH--MVEAVVIDPNLVKQQAQQIRSQREAAAKQEQERLDKLRRESEQL 89
Cdd:TIGR02794   1 RRAFLLSLLLHILLLGLLILGSLYHSVKPEPGGGaeIIQAVLVDPGAVAQQANRIQQQKKPAAKKEQERQKKLEQQAEEA 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   90 EKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQEQERAAKAEAERKLKEEA-------AKKAEAE 162
Cdd:TIGR02794  81 EKQRAAEQARQKELEQRAAAEKAAKQAEQAAKQAEEKQKQAEEAKAKQAAEAKAKAEAEAERKAKEeaakqaeEEAKAKA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  163 RVAKEAAAAKAEQERVAREKAAQEAQEKARKErEAAAKAEQERIAKEKAAKAAAEKARlekERAERAERERKEQEAALNN 242
Cdd:TIGR02794 161 AAEAKKKAEEAKKKAEAEAKAKAEAEAKAKAE-EAKAKAEAAKAKAAAEAAAKAEAEA---AAAAAAEAERKADEAELGD 236

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  243 IFAGLETESQNNSV-ARSQHVTSEAQRWGAIYTQLIQQNLLLEDSFKGKQCRVNLRLIPTGTgaiVGDLRILDGDSRLCA 321
Cdd:TIGR02794 237 IFGLASGSNAEKQGgARGAAAGSEVDKYAAIIQQAIQQNLYDDPSFRGKTCRLRIRLAPDGT---LLSVTKSSGDPALCQ 313

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 520907735  322 ATKRAVAQVGTFPLPKKDesDVIEKLKNINLTVVP 356
Cdd:TIGR02794 314 AALAAVAKAAKLPMPPSD--PVYEEFKNINLTFKP 346
TolA pfam06519
TolA C-terminal; This family consists of several bacterial TolA proteins as well as two ...
 257-354 1.02e-32

TolA C-terminal; This family consists of several bacterial TolA proteins as well as two eukaryotic proteins of unknown function. Tol proteins are involved in the translocation of group A colicins. Colicins are bacterial protein toxins, which are active against Escherichia coli and other related species (See pfam01024). TolA is anchored to the cytoplasmic membrane by a single membrane spanning segment near the N-terminus, leaving most of the protein exposed to the periplasm.


Pssm-ID: 399492 [Multi-domain]  Cd Length: 94  Bit Score: 117.53  E-value: 1.02e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  257 ARSQHVTSEAQRWGAIYTQLIQQNLLLEDSFKGKQCRVNLRLIPTGTgaiVGDLRILDGDSRLCAATKRAVAQVGTFPLP 336
Cdd:pfam06519   2 AGSGASGAEVDRYAGQIKQAIQSRFLKDDSFAGKTCRVRIKLAPDGT---LISVKVEGGDPALCQAAKAAVAKTAKIPKP 78

                          90
                  ....*....|....*...
gi 520907735  337 KKDesDVIEKLKNINLTV 354
Cdd:pfam06519  79 PSQ--DVYEKFKNINLDF 94
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 1-349 2.03e-17

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 82.55  E-value: 2.03e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   1 MKDQKSKKNDFKKPLAISVGLHVALVAALLWGT---DFTMSKPETSGHMVEAVVIDPNLVKQQAQQIRSQREAAAKQEQE 77
Cdd:PRK09510   1 MSKATEQNDKLKRAIIISVVLHIILFALLIWSSfdeNIEASGGGGGGSVIDAVMVDPGAVVEQYNRQQQQQKSAKRAEEQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  78 RLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQEQERA-AKAEAERKLKEEAA 156
Cdd:PRK09510  81 RKKKEQQQAEELQQKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAAAkAKAEAEAKRAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 157 KKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQE---------------RIAKEKAAKAAAEKARL 221
Cdd:PRK09510 161 KKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAKkkaaaeakkkaaaeaKAAAAKAAAEAKAAAEK 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 222 EKERAERAERERKEQEAALNNIFAGLET----------ESQNNSVARSQHVTSEAQRWGAIYTQL-------IQQNLLLE 284
Cdd:PRK09510 241 AAAAKAAEKAAAAKAAAEVDDLFGGLDSgknapktgggAKGNGAQGAGAGNGKKGGASGADIDQYagqiksaIQSKFYDA 320

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 520907735 285 DSFKGKQCRVNLRLIPTGTgaiVGDLRILDGDSRLCAAtkrAVAQVGTFPLPKKDESDVIEKLKN 349
Cdd:PRK09510 321 SSYAGKTCTLRIKLAPDGT---LLDIKKEGGDPALCQA---ALAAAKTAKIPKPPSQEVYEKFKN 379
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 58-252 2.53e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 2.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  58 KQQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQ 137
Cdd:COG1196  297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 138 EQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERIAKEKAAKAAAE 217
Cdd:COG1196  377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 520907735 218 KARLEKERAERAERERKEQEAALNNIFAGLETESQ 252
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAALAELLEELAEAAA 491
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 59-268 2.89e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 2.89e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  59 QQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQE 138
Cdd:COG1196  270 EELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEA 349

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 139 QERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERIAKEKAAKAAAEK 218
Cdd:COG1196  350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEA 429

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 520907735 219 ARLEKERAERAERERKEQEAALNNIFAGLETESQNNSVARSQHVTSEAQR 268
Cdd:COG1196  430 LAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAAL 479
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 58-315 1.79e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 56.10  E-value: 1.79e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  58 KQQAQQIRSQREAAAKQEQE---RLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEK 134
Cdd:COG1196  273 RLELEELELELEEAQAEEYEllaELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 135 ARQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERIAKEKAAKA 214
Cdd:COG1196  353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 215 AAEKARLEKERAERAERERKEQEAALNNIFAGLETESQNNSVARSQHVTSEAQRWGAIYTQLIQQNLLLEDSFKGKQCRV 294
Cdd:COG1196  433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512

                        250       260
                 ....*....|....*....|.
gi 520907735 295 NLRLIPTGTGAIVGDLRILDG 315
Cdd:COG1196  513 ALLLAGLRGLAGAVAVLIGVE 533
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 58-268 2.41e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 2.41e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  58 KQQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQ 137
Cdd:COG1196  255 LEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEE 334

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 138 EQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERIAKEKAAKAAAE 217
Cdd:COG1196  335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 520907735 218 KARLEKERAERAERERKEQEAALNNIFAGLETESQNNSVARSQHVTSEAQR 268
Cdd:COG1196  415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELL 465
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 59-268 3.14e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 3.14e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  59 QQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQE 138
Cdd:COG1196  249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL 328

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 139 QERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERIAKEKAAKAAAEK 218
Cdd:COG1196  329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 520907735 219 ARLEKERAERAERERKEQEAALNNIFAGLETESQNNSVARSQHVTSEAQR 268
Cdd:COG1196  409 EEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458
PTZ00121 PTZ00121
MAEBL; Provisional
 58-206 5.86e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.68  E-value: 5.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   58 KQQAQQIRSQREAAAKQEQ-ERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAekvrQQKEQEQKVAAEKAR 136
Cdd:PTZ00121 1606 KMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE----AKKAEEDKKKAEEAK 1681

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  137 QEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERI 206
Cdd:PTZ00121 1682 KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKK 1751
PTZ00121 PTZ00121
MAEBL; Provisional
 58-205 4.57e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 4.57e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   58 KQQAQQIRSQREAAAKQEQERLDKLRR--ESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKA 135
Cdd:PTZ00121 1533 AKKADEAKKAEEKKKADELKKAEELKKaeEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEA 1612

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 520907735  136 RQEQERAAKAE----AERKLKEEAAKKAEAERVAKEAAAA--KAEQERVAREKAAQEAQEKARKEREAAAKAEQER 205
Cdd:PTZ00121 1613 KKAEEAKIKAEelkkAEEEKKKVEQLKKKEAEEKKKAEELkkAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEK 1688
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 67-268 2.91e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 2.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  67 QREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAareaekVRQQKEQEQKVAAEKARQEQERAAKAE 146
Cdd:COG1196  236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELE------LEEAQAEEYELLAELARLEQDIARLEE 309

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735 147 aERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQERIAKEKAAKAAAEKARLEKERA 226
Cdd:COG1196  310 -RRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 520907735 227 ERAERERKEQEAALNNIFAGLETESQNNSVARSQHVTSEAQR 268
Cdd:COG1196  389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430
PTZ00121 PTZ00121
MAEBL; Provisional
 58-205 1.89e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 1.89e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   58 KQQAQQIRSQREAAAKQEQERlDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKvAAEKARQ 137
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLK-KKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK-AAEALKK 1696

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 520907735  138 EQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAeqervarEKAAQEAQEKARKEREAAAKAEQER 205
Cdd:PTZ00121 1697 EAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKA-------EEAKKEAEEDKKKAEEAKKDEEEKK 1757
PTZ00121 PTZ00121
MAEBL; Provisional
 58-205 2.43e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   58 KQQAQQIRSQREAAAKQEQERLDKLRRESE--QLEKNRKAEEER-IRQLKEQQAKEAKAAREAEKVRQQKE--------- 125
Cdd:PTZ00121 1521 AKKADEAKKAEEAKKADEAKKAEEKKKADElkKAEELKKAEEKKkAEEAKKAEEDKNMALRKAEEAKKAEEarieevmkl 1600

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  126 --QEQKVAAEKARQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKaRKEREAAAKAEQ 203
Cdd:PTZ00121 1601 yeEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEA-KKAEEDKKKAEE 1679


                  ..
gi 520907735  204 ER 205
Cdd:PTZ00121 1680 AK 1681
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 58-205 6.51e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 41.65  E-value: 6.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   58 KQQAQQIRSQREAAAK---QEQERLDKLRRESEQLEKNRKAEEE----RIRQLKEQQAKEAKAAreaekvrQQKEQEQKV 130
Cdd:pfam17380 388 QQKNERVRQELEAARKvkiLEEERQRKIQQQKVEMEQIRAEQEEarqrEVRRLEEERAREMERV-------RLEEQERQQ 460

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 520907735  131 AAEKARQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQER 205
Cdd:pfam17380 461 QVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERR 535
PTZ00121 PTZ00121
MAEBL; Provisional
 57-205 9.33e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 41.28  E-value: 9.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   57 VKQQAQQIRSQREAAAKQEQERlDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKAR 136
Cdd:PTZ00121 1307 AKKKAEEAKKADEAKKKAEEAK-KKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 520907735  137 QEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKA---RKEREAAAKAEQER 205
Cdd:PTZ00121 1386 KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAeeaKKADEAKKKAEEAK 1457
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
57-202 1.14e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 40.63  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  57 VKQQAQQIRSQREAAAKQEQE---RLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQK-EQEQKVAA 132
Cdd:COG2268  191 RRKIAEIIRDARIAEAEAEREteiAIAQANREAEEAELEQEREIETARIAEAEAELAKKKAEERREAETARaEAEAAYEI 270

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 520907735 133 EKARQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKERE-AAAKAE 202
Cdd:COG2268  271 AEANAEREVQRQLEIAEREREIELQEKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIRAkGLAEAE 341
PTZ00121 PTZ00121
MAEBL; Provisional
 58-205 1.17e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   58 KQQAQQIRSQREAAAKQEQERLDKLRRESEQLeknRKAEEERirqlKEQQAKEAKAAREAEKVRQQKE---QEQKVAAEK 134
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEAKKAEEAKKADEA---KKAEEAK----KADEAKKAEEKKKADELKKAEElkkAEEKKKAEE 1568

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 520907735  135 ARQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQER 205
Cdd:PTZ00121 1569 AKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK 1639
PTZ00121 PTZ00121
MAEBL; Provisional
 66-205 1.30e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   66 SQREAAAKQEQER-LDKLRR--ESEQLEKNRKAEEERirqlKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQEQERA 142
Cdd:PTZ00121 1266 ARRQAAIKAEEARkADELKKaeEKKKADEAKKAEEKK----KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEA 1341

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 520907735  143 AKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQER 205
Cdd:PTZ00121 1342 KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDK 1404
PTZ00121 PTZ00121
MAEBL; Provisional
 53-205 1.44e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   53 DPNLVKQQAQQIRSQREAaaKQEQERLDKLRRESEQLEKNRKAEEERIRqlKEQQAKEAKAAREAEKVRQQKEQEQKVAA 132
Cdd:PTZ00121 1575 DKNMALRKAEEAKKAEEA--RIEEVMKLYEEEKKMKAEEAKKAEEAKIK--AEELKKAEEEKKKVEQLKKKEAEEKKKAE 1650

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 520907735  133 EKARQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERvAREKAAQEAQEKARKEREAAAKAEQER 205
Cdd:PTZ00121 1651 ELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK-KEAEEAKKAEELKKKEAEEKKKAEELK 1722
PTZ00121 PTZ00121
MAEBL; Provisional
 59-205 1.45e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   59 QQAQQIRSQREAAAKQEQERLDKLRRESEQL---EKNRKAEEERirqlKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKA 135
Cdd:PTZ00121 1348 AKAEAEAAADEAEAAEEKAEAAEKKKEEAKKkadAAKKKAEEKK----KADEAKKKAEEDKKKADELKKAAAAKKKADEA 1423

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 520907735  136 RQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKA---RKEREAAAKAEQER 205
Cdd:PTZ00121 1424 KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAeeaKKADEAKKKAEEAK 1496
PTZ00121 PTZ00121
MAEBL; Provisional
 59-238 2.02e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 2.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   59 QQAQQIRSQREAAAKQEQER-LDKLRRESEQLEKnrKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKARQ 137
Cdd:PTZ00121 1296 KKAEEKKKADEAKKKAEEAKkADEAKKKAEEAKK--KADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK 1373

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  138 EQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKA---RKEREAAAKAEQERiaKEKAAKA 214
Cdd:PTZ00121 1374 EEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAeekKKADEAKKKAEEAK--KADEAKK 1451

                         170       180
                  ....*....|....*....|....
gi 520907735  215 AAEKARLEKERAERAERERKEQEA 238
Cdd:PTZ00121 1452 KAEEAKKAEEAKKKAEEAKKADEA 1475
PTZ00121 PTZ00121
MAEBL; Provisional
 59-204 2.07e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.12  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   59 QQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEA-KAAREAEKVRQQKEQEQKVAAEKARQ 137
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElKKAEEKKKADEAKKAEEKKKADEAKK 1309

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 520907735  138 EQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAqEKARKEREAAAKAEQE 204
Cdd:PTZ00121 1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEA-EAAEEKAEAAEKKKEE 1375
PTZ00121 PTZ00121
MAEBL; Provisional
 57-205 2.71e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 2.71e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   57 VKQQAQQIRSQREAAAKQEQER-LDKLRRESEQLEKnrKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKA 135
Cdd:PTZ00121 1462 AKKKAEEAKKADEAKKKAEEAKkADEAKKKAEEAKK--KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEA 1539

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  136 RQEQER-----------------AAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAA 198
Cdd:PTZ00121 1540 KKAEEKkkadelkkaeelkkaeeKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619


                  ....*..
gi 520907735  199 AKAEQER 205
Cdd:PTZ00121 1620 IKAEELK 1626
PTZ00121 PTZ00121
MAEBL; Provisional
 60-205 3.45e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 3.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   60 QAQQIRSQREAAAKQEQERLDKLRRESEQL---EKNRKAEEERirqlKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKAR 136
Cdd:PTZ00121 1273 KAEEARKADELKKAEEKKKADEAKKAEEKKkadEAKKKAEEAK----KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAA 1348

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 520907735  137 QEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQER 205
Cdd:PTZ00121 1349 KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417
GBP_C pfam02841
Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral ...
 58-141 5.41e-03

Guanylate-binding protein, C-terminal domain; Transcription of the anti-viral guanylate-binding protein (GBP) is induced by interferon-gamma during macrophage induction. This family contains GBP1 and GPB2, both GTPases capable of binding GTP, GDP and GMP.


Pssm-ID: 460721 [Multi-domain]  Cd Length: 297  Bit Score: 38.04  E-value: 5.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   58 KQQAQQIRSQREAAAKQEQERLDKLRRESEQ-LEKNRKAEEERIRQLKEQQAKEakaareaekvRQQKEQEQKVAAEKAR 136
Cdd:pfam02841 202 KEKAIEAERAKAEAAEAEQELLREKQKEEEQmMEAQERSYQEHVKQLIEKMEAE----------REQLLAEQERMLEHKL 271


                  ....*
gi 520907735  137 QEQER 141
Cdd:pfam02841 272 QEQEE 276
PTZ00121 PTZ00121
MAEBL; Provisional
 57-239 6.95e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.58  E-value: 6.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   57 VKQQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKvrQQKEQEQKVAAEKAR 136
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA--KKKAEEDKKKADELK 1411

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735  137 QEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKA---RKEREAAAKAEQERiaKEKAAK 213
Cdd:PTZ00121 1412 KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAeeaKKADEAKKKAEEAK--KADEAK 1489

                         170       180
                  ....*....|....*....|....*.
gi 520907735  214 AAAEKARLEKERAERAERERKEQEAA 239
Cdd:PTZ00121 1490 KKAEEAKKKADEAKKAAEAKKKADEA 1515
PTZ00121 PTZ00121
MAEBL; Provisional
 59-205 7.19e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.58  E-value: 7.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   59 QQAQQIRSQREAAAKQEQERLDKLRRESE---QLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKvaAEKA 135
Cdd:PTZ00121 1206 RKAEEERKAEEARKAEDAKKAEAVKKAEEakkDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARK--ADEL 1283

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 520907735  136 RQEQERAaKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKA--RKEREAAAKAEQER 205
Cdd:PTZ00121 1284 KKAEEKK-KADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAeeAKKAAEAAKAEAEA 1354
PTZ00121 PTZ00121
MAEBL; Provisional
 57-205 7.32e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.58  E-value: 7.32e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   57 VKQQAQQIRSQREAAAKQEQER-LDKLRRESEQLEKNRKAEEERIRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKA 135
Cdd:PTZ00121 1423 AKKKAEEKKKADEAKKKAEEAKkADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEA 1502

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 520907735  136 RQEQERAAKAE----AERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQEKARKEREAAAKAEQER 205
Cdd:PTZ00121 1503 KKAAEAKKKADeakkAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576
PTZ00121 PTZ00121
MAEBL; Provisional
 56-202 8.85e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.20  E-value: 8.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907735   56 LVKQQAQQIRSQREAAAKQEQERLDKLRRESEQLEKNRKAEEERiRQLKEQQAKEAKAAREAEKVRQQKEQEQKVAAEKA 135
Cdd:PTZ00121 1638 LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK-KAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKK 1716

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 520907735  136 RQEQERAAKAEAERKLKEEAAKKAEAERVAKEAAAAKAEQERVAREKAAQEAQ-EKARKEREAAAKAE 202
Cdd:PTZ00121 1717 KAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKaEEIRKEKEAVIEEE 1784
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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