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Conserved domains on  [gi|520907757|ref|WP_020327767|]
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MULTISPECIES: ABC transporter permease [Vibrio]

Protein Classification

ABC transporter permease( domain architecture ID 11467922)

ABC transporter permease is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter, which may be involved in the transport of one or more from a variety of substrates such as nopaline and octopine

Gene Ontology:  GO:0140359|GO:0042626|GO:0043190|GO:0016020
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 1-223 1.12e-114

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 326.67  E-value: 1.12e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   1 MDFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFF 80
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  81 PVKGT-LWE---NAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEV 156
Cdd:COG4160   81 WVRESwLWPllrDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNEV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 520907757 157 IFMLHGSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRFLAYLRP 223
Cdd:COG4160  161 ILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRP 227
 
Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 1-223 1.12e-114

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 326.67  E-value: 1.12e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   1 MDFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFF 80
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  81 PVKGT-LWE---NAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEV 156
Cdd:COG4160   81 WVRESwLWPllrDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNEV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 520907757 157 IFMLHGSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRFLAYLRP 223
Cdd:COG4160  161 ILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRP 227
PRK15069 PRK15069
histidine ABC transporter permease HisM;
14-223 1.98e-82

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 245.34  E-value: 1.98e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  14 FSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFPVKGTLWENAWF- 92
Cdd:PRK15069  20 FTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSLEIVRGTDLLDAFFr 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  93 ----CALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHGSAVAGI 168
Cdd:PRK15069 100 sglnCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFT 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 520907757 169 VTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRFLAYLRP 223
Cdd:PRK15069 180 ATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRWLAHLKP 234
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 2-217 2.52e-31

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 114.18  E-value: 2.52e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757    2 DFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFP 81
Cdd:TIGR03003   2 DWEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDIGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   82 VKgtlweNAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLH 161
Cdd:TIGR03003  82 RL-----PALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFK 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 520907757  162 GSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRF 217
Cdd:TIGR03003 157 ETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 17-208 8.79e-21

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 85.79  E-value: 8.79e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  17 LWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFPvkGTLWENAWFCALV 96
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG--WGILPGLGLPALI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  97 AFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHGSAVAGIVTIMDLTG 176
Cdd:cd06261   79 LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG 158

                        170       180       190
                 ....*....|....*....|....*....|..
gi 520907757 177 AARLVNSRYYAPFESFLTAGLFYMSLTFMIIF 208
Cdd:cd06261  159 PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 31-170 2.16e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 57.69  E-value: 2.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   31 GLSIAIPLAIARNSRNYVISTPawgYIYFFRGTPLLVQLYLIYYGMDQffpvkgTLWENAWFCALVAFVLNTSAYTAEII 110
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRP---LIDLLQALPSFVLAILLVVIAIL------SILGHGILPAIILALLGWAGYARLIR 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  111 RGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHGSAVAGIVT 170
Cdd:pfam00528  72 RAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG 131
 
Name Accession Description Interval E-value
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 1-223 1.12e-114

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 326.67  E-value: 1.12e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   1 MDFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFF 80
Cdd:COG4160    1 MDLDLLFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  81 PVKGT-LWE---NAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEV 156
Cdd:COG4160   81 WVRESwLWPllrDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRRIILPSALRRALPAYSNEV 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 520907757 157 IFMLHGSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRFLAYLRP 223
Cdd:COG4160  161 ILMLKATALASTITVMDLTGVARRIYSRTYDPFEPFLIAALIYLVITFLLTRLFRLLERRLLRHLRP 227
PRK15069 PRK15069
histidine ABC transporter permease HisM;
14-223 1.98e-82

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 245.34  E-value: 1.98e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  14 FSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFPVKGTLWENAWF- 92
Cdd:PRK15069  20 FTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSLEIVRGTDLLDAFFr 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  93 ----CALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHGSAVAGI 168
Cdd:PRK15069 100 sglnCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTFKLYRRIILPSALRRALPAYSNEVILMLHATTLAFT 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 520907757 169 VTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRFLAYLRP 223
Cdd:PRK15069 180 ATVPDILKIARDINSATYQPFQAFGIAAVLYLIISFVLISLFRRAERRWLAHLKP 234
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 1-217 1.50e-72

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 219.56  E-value: 1.50e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   1 MDFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFF 80
Cdd:COG0765    3 FDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFGLPLLG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  81 pvkgtLWENAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFML 160
Cdd:COG0765   83 -----IDLSPFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRRIILPQALRIILPPLGNEFISLL 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 520907757 161 HGSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRF 217
Cdd:COG0765  158 KDTSLVSVIGVPELTRAAQQIASRTFRPFEVYLVAALIYLVLTLPLSLLARRLERRL 214
artM PRK11122
arginine ABC transporter permease ArtM;
10-222 4.89e-50

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 162.44  E-value: 4.89e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  10 LPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQF-----FPVKG 84
Cdd:PRK11122   5 LPELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFpwlqeYPWLW 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  85 TLWENAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRrVVLPSALRRALPAYSNEVIFMLHGSA 164
Cdd:PRK11122  85 HLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLR-ILLPYAFKRALSSYSNEVVLVFKSTS 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 520907757 165 VAGIVTIMDLTGAARLVNSRYYAPFeSFLTAGLFYMSLTFMIIFCFKKAEKRFLAYLR 222
Cdd:PRK11122 164 LAYTITLMDVMGYSQLLYGRTYDVM-VFGAAGIIYLVVNGLLTLLMRLIERKALAFER 220
PRK15100 PRK15100
cystine ABC transporter permease;
3-199 5.03e-40

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 136.80  E-value: 5.03e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   3 FSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFfpv 82
Cdd:PRK15100   5 IQLVIDSAPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQF--- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  83 kgTLWENAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHG 162
Cdd:PRK15100  82 --GIELDPIPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKD 159

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 520907757 163 SAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFY 199
Cdd:PRK15100 160 TSLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIY 196
ArtQ COG4215
ABC-type arginine transport system, permease component [Amino acid transport and metabolism];
8-217 5.89e-38

ABC-type arginine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443361 [Multi-domain]  Cd Length: 238  Bit Score: 131.79  E-value: 5.89e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   8 GSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFPVKGTLW 87
Cdd:COG4215   13 GWGPALLAGALVTLELALLSLLLGLVLGLLGALAKLSGNRPLRWLATGYTTVVRGVPDLLLILLLYFGGQILLNALADLF 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  88 ENAWFCALVAFVLNT-------SAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFML 160
Cdd:COG4215   93 GYDGFIEINPFVAGVlalgfvfGAYATEVFRGAFLAVPKGQIEAARAYGMSRWQVFRRILLPQMWRYALPGLGNNWLVLL 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 520907757 161 HGSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRF 217
Cdd:COG4215  173 KDTALVSVIGLVDLVRQAQEAAGSTREPFTFYLAAALIYLALTTVSELVLARLERRA 229
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 2-217 2.52e-31

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 114.18  E-value: 2.52e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757    2 DFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFP 81
Cdd:TIGR03003   2 DWEFVRQILPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDIGI 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   82 VKgtlweNAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLH 161
Cdd:TIGR03003  82 RL-----PALVAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTYRHIILPQAIPPIIPALGNYLVAMFK 156

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 520907757  162 GSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRF 217
Cdd:TIGR03003 157 ETPVLSAITVLELMNQAKSIGNSTFRYLEPMTLVGVFFLILSIISVFFLRRLEARL 212
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 2-216 1.63e-29

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 109.37  E-value: 1.63e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   2 DFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFP 81
Cdd:PRK09494   4 DWSAIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFALPMAFN 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  82 vkgTLWENAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLH 161
Cdd:PRK09494  84 ---DLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLALRRMLPPLGNQWIISIK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 520907757 162 GSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKR 216
Cdd:PRK09494 161 DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVIYLIITLVLSFILRRLERR 215
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
15-217 2.02e-26

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 102.06  E-value: 2.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  15 SGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQF-------FPVKGTLW 87
Cdd:PRK11123   9 SAAGMTVGLAVCALIVGLALAMLFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSQLlltlsdgFTLNLGFV 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  88 E------------NAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNE 155
Cdd:PRK11123  89 QipvqmdienfevSPFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRHALPGLGNQ 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 520907757 156 VIFMLHGSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTFMIIFCFKKAEKRF 217
Cdd:PRK11123 169 WLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIIAAAIYLVITLISQYILKRIELRA 230
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 9-112 2.17e-21

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 84.89  E-value: 2.17e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757    9 SLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFpvkgtLWE 88
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLIG-----IRL 75

                          90       100
                  ....*....|....*....|....
gi 520907757   89 NAWFCALVAFVLNTSAYTAEIIRG 112
Cdd:TIGR01726  76 SPLTAAVIALTLFYGAYLAEIFRG 99
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 17-208 8.79e-21

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 85.79  E-value: 8.79e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  17 LWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFPvkGTLWENAWFCALV 96
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG--WGILPGLGLPALI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  97 AFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHGSAVAGIVTIMDLTG 176
Cdd:cd06261   79 LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG 158

                        170       180       190
                 ....*....|....*....|....*....|..
gi 520907757 177 AARLVNSRYYAPFESFLTAGLFYMSLTFMIIF 208
Cdd:cd06261  159 PGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
14-203 9.03e-17

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 75.99  E-value: 9.03e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  14 FSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFF-PVKGTL-WENAW 91
Cdd:PRK15135  10 LQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALnSVTEALgVGQID 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  92 FCALVAFVLNTS----AYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHGSAVAG 167
Cdd:PRK15135  90 IDPMVAGIITLGfiygAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQVILKATALVS 169

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 520907757 168 IVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLT 203
Cdd:PRK15135 170 LLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFT 205
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
2-204 1.39e-16

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 75.25  E-value: 1.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   2 DFSLIIGSLPIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRNYVISTPAWGYIYFFRGTPLLVQL---YLIYYGMDQ 78
Cdd:PRK15107   5 DWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLlwfYLIVPGFLQ 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  79 FFPVKGTLWENAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIF 158
Cdd:PRK15107  85 NVLGLSPKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIV 164

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 520907757 159 MLHGSAVAGIVTIMDLTGAARLVNSRYYAPFESFLTAGLFYMSLTF 204
Cdd:PRK15107 165 LFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISL 210
BatB COG4597
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 92-150 6.92e-11

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443651 [Multi-domain]  Cd Length: 397  Bit Score: 60.93  E-value: 6.92e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  92 FCAL-VAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALP 150
Cdd:COG4597  265 FVALlLALSLYTAAFIAEIVRAGIQAVSKGQTEAARALGLRPGQTLRLVVLPQALRVIIP 324
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 31-170 2.16e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 57.69  E-value: 2.16e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   31 GLSIAIPLAIARNSRNYVISTPawgYIYFFRGTPLLVQLYLIYYGMDQffpvkgTLWENAWFCALVAFVLNTSAYTAEII 110
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRP---LIDLLQALPSFVLAILLVVIAIL------SILGHGILPAIILALLGWAGYARLIR 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  111 RGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRALPAYSNEVIFMLHGSAVAGIVT 170
Cdd:pfam00528  72 RAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG 131
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 11-145 1.51e-06

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 47.45  E-value: 1.51e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  11 PIYFSGLWTTVWLVGLSLVIGLSIAIPLAIArNSRNYVISTPAWGYIYFFRGTPLLVQLYLIYYGMDQFFPVKGTLwenA 90
Cdd:COG0600   57 GELWEHLLASLLRVLLGFALAALLGVPLGLL-LGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGIGEASKIFV---I 132

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 520907757  91 WFCALVAFVLNTsaytaeiiRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSAL 145
Cdd:COG0600  133 FLGAFFPILLNT--------AAGVRSVDPELLELARSLGASRWQILRKVVLPAAL 179
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
11-151 5.89e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 43.23  E-value: 5.89e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  11 PIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRN-------------------YVISTpAWGYIYFFRGtplLVQLYL 71
Cdd:COG1178   50 PYLWRALGNTLLLALLVTLLSLLLGVPLAWLLARTDfpgrrllrwllllplalppYVVAL-AWIALFGPNG---LLNTLL 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  72 IYYGMDQFFPVKGtlwenaWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPsALRRALPA 151
Cdd:COG1178  126 RALFGLEPPDIYG------LGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLP-LLRPAIAA 198
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 17-145 2.89e-04

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 40.42  E-value: 2.89e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  17 LWTTVWLVGLSLVIGLSIAIPLAI--ARNSRNYVISTPAWGYIYFFRGTPLLVQLyliyygmdqfFPVKGTLWENAwfca 94
Cdd:COG1174   20 LLEHLLLVLLALLIALLIAVPLGIliTRRRRLAGLVLGVANILQTIPSLALLALL----------IPLLGIGPAPA---- 85

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 520907757  95 LVAFVLntsaYT-AEIIRGAINGL---PKGEVEAAKAYGMGTWKTYRRVVLPSAL 145
Cdd:COG1174   86 IIALVL----YAlLPILRNTYTGLrsvDPAVVEAARGMGMTPWQRLWRVELPLAL 136
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 10-149 1.46e-03

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 38.68  E-value: 1.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757   10 LPIYFSGLWTTVWLVGLSLVIGLSIAIPLAI--ARN-SRNYVISTPAWGYIYFFRGTPLLVqLYLIYYGMDQFFPVKGTL 86
Cdd:TIGR01097  53 LPRILKALLETLAMAILGTVLAAVLAVPLALlaARNiTPSPWLYGLARLLLNFLRAIPELV-WALIFVAAVGLGPFAGVL 131

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 520907757   87 wenawfcalvAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSALRRAL 149
Cdd:TIGR01097 132 ----------ALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFL 184
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-149 5.80e-03

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 37.04  E-value: 5.80e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 520907757  11 PIYFSGLWTTVWLVGLSLVIGLSIAIPLAIARNSRN-------------YVISTPAWGYI--YFFRGTPLLVQLYLIYYG 75
Cdd:COG1175   72 PRFWNALGNTLLFTVVSVPLQLVLGLLLALLLNRKLrgrgffrtlfflpWVISPVVVALIwkWLFNPDYGLLNALLGALG 151

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 520907757  76 MDQFFPVKGTLWenAWFCALVAFVLNTSAYTAEIIRGAINGLPKGEVEAAKAYGMGTWKTYRRVVLPSaLRRAL 149
Cdd:COG1175  152 LEPINWLGDPSL--ALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPL-LRPTI 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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