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Conserved domains on  [gi|521289059|ref|WP_020453327|]
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MULTISPECIES: spore coat protein GerQ [Bacillus]

Protein Classification

spore coat protein GerQ( domain architecture ID 10560427)

spore coat protein GerQ is essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GerQ COG5889
Spore coat protein GerQ/YwdL (inner spore coat) [Cell cycle control, cell division, chromosome ...
 15-178 1.40e-70

Spore coat protein GerQ/YwdL (inner spore coat) [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 444591 [Multi-domain]  Cd Length: 161  Bit Score: 210.80  E-value: 1.40e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  15 EMPDFRQQMGPNPYPQMGQMGQMYQ--QHGQQPFTQTGGQQSYQQPGpqlfqpqpAGVQVPPMPSAQQ-TSPSIPGMLPL 91
Cdd:COG5889    3 ENENQRQQPQQNPYYYYPQYQPAYYpsMQGQQPQQPMQQQQQGPQPG--------FGQQIPQMPTGQQpTGPSVPGMLPL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  92 EQSYIENILRLNRGKVATVYMTFENNPEWNAKVFRGEIEAAGRDHIILSDRKTGTRYLLLMVYLDYITFDEPITYDYPYS 171
Cdd:COG5889   75 EQSYIENILRLNRGKVATVYMTFENNSQWNAKIFRGVIEAAGRDHIILSDPQTGKRYLLLMVYLDYVTFDEEINYEYPYA 154


                 ....*..
gi 521289059 172 MASYTPR 178
Cdd:COG5889  155 LATYSPR 161
 
Name Accession Description Interval E-value
GerQ COG5889
Spore coat protein GerQ/YwdL (inner spore coat) [Cell cycle control, cell division, chromosome ...
 15-178 1.40e-70

Spore coat protein GerQ/YwdL (inner spore coat) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444591 [Multi-domain]  Cd Length: 161  Bit Score: 210.80  E-value: 1.40e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  15 EMPDFRQQMGPNPYPQMGQMGQMYQ--QHGQQPFTQTGGQQSYQQPGpqlfqpqpAGVQVPPMPSAQQ-TSPSIPGMLPL 91
Cdd:COG5889    3 ENENQRQQPQQNPYYYYPQYQPAYYpsMQGQQPQQPMQQQQQGPQPG--------FGQQIPQMPTGQQpTGPSVPGMLPL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  92 EQSYIENILRLNRGKVATVYMTFENNPEWNAKVFRGEIEAAGRDHIILSDRKTGTRYLLLMVYLDYITFDEPITYDYPYS 171
Cdd:COG5889   75 EQSYIENILRLNRGKVATVYMTFENNSQWNAKIFRGVIEAAGRDHIILSDPQTGKRYLLLMVYLDYVTFDEEINYEYPYA 154


                 ....*..
gi 521289059 172 MASYTPR 178
Cdd:COG5889  155 LATYSPR 161
Spore_GerQ pfam09671
Spore coat protein (Spore_GerQ); Members of this protein family are the spore coat protein ...
 91-166 7.06e-58

Spore coat protein (Spore_GerQ); Members of this protein family are the spore coat protein GerQ of endospore-forming Firmicutes (low GC Gram-positive bacteria). This protein is cross-linked by a spore coat-associated transglutaminase.


Pssm-ID: 401563  Cd Length: 76  Bit Score: 175.61  E-value: 7.06e-58
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521289059   91 LEQSYIENILRLNRGKVATVYMTFENNPEWNAKVFRGEIEAAGRDHIILSDRKTGTRYLLLMVYLDYITFDEPITY 166
Cdd:pfam09671   1 LEQSYIENILRLNRGKLATFYMTFENNSEWNAKIFRGIIEAAGRDHIIISDPQTGKRYLLLMVYLDYVTFDEEINY 76
spore_gerQ TIGR02728
spore coat protein GerQ; Members of this protein family are the spore coat protein GerQ of ...
 89-170 2.98e-49

spore coat protein GerQ; Members of this protein family are the spore coat protein GerQ of endospore-forming Firmicutes (low GC Gram-positive bacteria). This protein is cross-linked by a spore coat-associated transglutaminase. [Cellular processes, Sporulation and germination]


Pssm-ID: 131775  Cd Length: 82  Bit Score: 153.90  E-value: 2.98e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059   89 LPLEQSYIENILRLNRGKVATVYMTFENNPEWNAKVFRGEIEAAGRDHIILSDRKTGTRYLLLMVYLDYITFDEPITYDY 168
Cdd:TIGR02728   1 LPVEQSYIENILRMNRGKTATVYMTFENSPEWAARVFRGQIENAGRDHIVISDPQSGMRYLLLMVYLDYLTFDEEIRYPY 80


                  ..
gi 521289059  169 PY 170
Cdd:TIGR02728  81 PY 82
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 8-81 1.40e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.61  E-value: 1.40e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 521289059    8 IQPLQELEMPdfRQQMGPNPYPQMGQMGQMYQQHGQQPFTQTGGQQSYQQP-GPQLFQPQPAGVQVPPMPSAQQT 81
Cdd:PRK10263  772 VAPQPQYQQP--QQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPqQPVAPQPQYQQPQQPVAPQPQDT 844
KLF1_2_4_N-like cd22056
N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of ...
 16-91 1.05e-03

N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of Kruppel-like factor (KLF)1, KLF2, and KLF4; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specifity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domains of an unknown subfamily of KLFs, predominantly found in fish, related to the N-terminal domains of KLF1, KLF2, and KLF4.


Pssm-ID: 409231 [Multi-domain]  Cd Length: 339  Bit Score: 38.49  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  16 MPDFRQQMGPNPYPQMGQMGQMYQQHGQQP----FTQTGGQQSYQQPGPQLFQPQ------PAGVQVPPMPSAQQTSPSI 85
Cdd:cd22056  228 GPGALQGRGGRGGPDCHLLHSSHHHHHHHHlqyqYMNAPYPPHYAHQGAPQFHGQysvfrePMRVHHQGHPGSMLTPPSS 307


                 ....*.
gi 521289059  86 PGMLPL 91
Cdd:cd22056  308 PPLLEF 313
 
Name Accession Description Interval E-value
GerQ COG5889
Spore coat protein GerQ/YwdL (inner spore coat) [Cell cycle control, cell division, chromosome ...
 15-178 1.40e-70

Spore coat protein GerQ/YwdL (inner spore coat) [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 444591 [Multi-domain]  Cd Length: 161  Bit Score: 210.80  E-value: 1.40e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  15 EMPDFRQQMGPNPYPQMGQMGQMYQ--QHGQQPFTQTGGQQSYQQPGpqlfqpqpAGVQVPPMPSAQQ-TSPSIPGMLPL 91
Cdd:COG5889    3 ENENQRQQPQQNPYYYYPQYQPAYYpsMQGQQPQQPMQQQQQGPQPG--------FGQQIPQMPTGQQpTGPSVPGMLPL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  92 EQSYIENILRLNRGKVATVYMTFENNPEWNAKVFRGEIEAAGRDHIILSDRKTGTRYLLLMVYLDYITFDEPITYDYPYS 171
Cdd:COG5889   75 EQSYIENILRLNRGKVATVYMTFENNSQWNAKIFRGVIEAAGRDHIILSDPQTGKRYLLLMVYLDYVTFDEEINYEYPYA 154


                 ....*..
gi 521289059 172 MASYTPR 178
Cdd:COG5889  155 LATYSPR 161
Spore_GerQ pfam09671
Spore coat protein (Spore_GerQ); Members of this protein family are the spore coat protein ...
 91-166 7.06e-58

Spore coat protein (Spore_GerQ); Members of this protein family are the spore coat protein GerQ of endospore-forming Firmicutes (low GC Gram-positive bacteria). This protein is cross-linked by a spore coat-associated transglutaminase.


Pssm-ID: 401563  Cd Length: 76  Bit Score: 175.61  E-value: 7.06e-58
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 521289059   91 LEQSYIENILRLNRGKVATVYMTFENNPEWNAKVFRGEIEAAGRDHIILSDRKTGTRYLLLMVYLDYITFDEPITY 166
Cdd:pfam09671   1 LEQSYIENILRLNRGKLATFYMTFENNSEWNAKIFRGIIEAAGRDHIIISDPQTGKRYLLLMVYLDYVTFDEEINY 76
spore_gerQ TIGR02728
spore coat protein GerQ; Members of this protein family are the spore coat protein GerQ of ...
 89-170 2.98e-49

spore coat protein GerQ; Members of this protein family are the spore coat protein GerQ of endospore-forming Firmicutes (low GC Gram-positive bacteria). This protein is cross-linked by a spore coat-associated transglutaminase. [Cellular processes, Sporulation and germination]


Pssm-ID: 131775  Cd Length: 82  Bit Score: 153.90  E-value: 2.98e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059   89 LPLEQSYIENILRLNRGKVATVYMTFENNPEWNAKVFRGEIEAAGRDHIILSDRKTGTRYLLLMVYLDYITFDEPITYDY 168
Cdd:TIGR02728   1 LPVEQSYIENILRMNRGKTATVYMTFENSPEWAARVFRGQIENAGRDHIVISDPQSGMRYLLLMVYLDYLTFDEEIRYPY 80


                  ..
gi 521289059  169 PY 170
Cdd:TIGR02728  81 PY 82
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 8-81 1.40e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 41.61  E-value: 1.40e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 521289059    8 IQPLQELEMPdfRQQMGPNPYPQMGQMGQMYQQHGQQPFTQTGGQQSYQQP-GPQLFQPQPAGVQVPPMPSAQQT 81
Cdd:PRK10263  772 VAPQPQYQQP--QQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPqQPVAPQPQYQQPQQPVAPQPQDT 844
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 16-86 5.83e-04

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 39.68  E-value: 5.83e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 521289059   16 MPDFRQQMGPNPYPQMGQMGQMY--QQHGQQPFTQTGGQQSYQQPG-PQLFQPQPAGVQVPPMPSAQQTSPSIP 86
Cdd:PRK10263  750 EPVQQPQQPVAPQQQYQQPQQPVapQPQYQQPQQPVAPQPQYQQPQqPVAPQPQYQQPQQPVAPQPQYQQPQQP 823
KLF1_2_4_N-like cd22056
N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of ...
 16-91 1.05e-03

N-terminal domain of Kruppel-like factors with similarity to the N-terminal domains of Kruppel-like factor (KLF)1, KLF2, and KLF4; Kruppel/Krueppel-like transcription factors (KLFs) belong to a family of proteins called the Specificity Protein (SP)/KLF family, characterized by a C-terminal DNA-binding domain of 81 amino acids consisting of three Kruppel-like C2H2 zinc fingers. These factors bind to a loose consensus motif, namely NNRCRCCYY (where N is any nucleotide; R is A/G, and Y is C/T), such as the recurring motifs in GC and GT boxes (5'-GGGGCGGGG-3' and 5-GGTGTGGGG-3') that are present in promoters and more distal regulatory elements of mammalian genes. Members of the KLF family can act as activators or repressors of transcription depending on cell and promoter context. KLFs regulate various cellular functions, such as proliferation, differentiation, and apoptosis, as well as the development and homeostasis of several types of tissue. In addition to the C-terminal DNA-binding domain, each KLF also has a unique N-terminal activation/repression domain that confers specifity and allows it to bind specifically to a certain partner, leading to distinct activities in vivo. This model represents the N-terminal domains of an unknown subfamily of KLFs, predominantly found in fish, related to the N-terminal domains of KLF1, KLF2, and KLF4.


Pssm-ID: 409231 [Multi-domain]  Cd Length: 339  Bit Score: 38.49  E-value: 1.05e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059  16 MPDFRQQMGPNPYPQMGQMGQMYQQHGQQP----FTQTGGQQSYQQPGPQLFQPQ------PAGVQVPPMPSAQQTSPSI 85
Cdd:cd22056  228 GPGALQGRGGRGGPDCHLLHSSHHHHHHHHlqyqYMNAPYPPHYAHQGAPQFHGQysvfrePMRVHHQGHPGSMLTPPSS 307


                 ....*.
gi 521289059  86 PGMLPL 91
Cdd:cd22056  308 PPLLEF 313
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 12-103 5.66e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 36.60  E-value: 5.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059   12 QELEMPDFRQQMGPNPYPQMGQMGQM---YQQHGQQPFTQTGGQQSYQQPG-PQLFQPQPAGVQVPPMPSAQQTSPSIPG 87
Cdd:PRK10263  758 PVAPQQQYQQPQQPVAPQPQYQQPQQpvaPQPQYQQPQQPVAPQPQYQQPQqPVAPQPQYQQPQQPVAPQPQYQQPQQPV 837

                          90
                  ....*....|....*.
gi 521289059   88 MLPLEQSYIENILRLN 103
Cdd:PRK10263  838 APQPQDTLLHPLLMRN 853
PAT1 pfam09770
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ...
 11-93 5.86e-03

Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.


Pssm-ID: 401645 [Multi-domain]  Cd Length: 846  Bit Score: 36.55  E-value: 5.86e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059   11 LQELE--MPDFRQQMGPNPYPQMGQMGQMYQQHGQQPFTQTGGQQSYQQ-PGPQLFQPQPAGVQVPPM-----PSAQQTS 82
Cdd:pfam09770 196 LEEVEaaMRAQAKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQqPQQQPQQPQQHPGQGHPVtilqrPQSPQPD 275

                          90
                  ....*....|.
gi 521289059   83 PSIPGMLPLEQ 93
Cdd:pfam09770 276 PAQPSIQPQAQ 286
PABP-1234 TIGR01628
polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins ...
 4-82 8.00e-03

polyadenylate binding protein, human types 1, 2, 3, 4 family; These eukaryotic proteins recognize the poly-A of mRNA and consists of four tandem RNA recognition domains at the N-terminus (rrm: pfam00076) followed by a PABP-specific domain (pfam00658) at the C-terminus. The protein is involved in the transport of mRNA's from the nucleus to the cytoplasm. There are four paralogs in Homo sapiens which are expressed in testis, platelets, broadly expressed and of unknown tissue range.


Pssm-ID: 130689 [Multi-domain]  Cd Length: 562  Bit Score: 36.32  E-value: 8.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059    4 KKNQIQPLQELEM---PDFRQQMGPNPYPQMGQMGQMYQQHGQQPFTQT--GGQQSYQQPGPQLFQPQPAGVQVPPMPSA 78
Cdd:TIGR01628 364 KEQRRAHLQDQFMqlqPRMRQLPMGSPMGGAMGQPPYYGQGPQQQFNGQplGWPRMSMMPTPMGPGGPLRPNGLAPMNAV 443


                  ....
gi 521289059   79 QQTS 82
Cdd:TIGR01628 444 RAPS 447
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 5-86 8.18e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 36.22  E-value: 8.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 521289059    5 KNQIQPLQELEMPDFRQQMGPNPYPQMgqmgQMYQQHGQQPFTQTGGQQSYQQPGPQLFQPQPAGVQVPPMPSAQQTSPS 84
Cdd:PRK10263  762 QQQYQQPQQPVAPQPQYQQPQQPVAPQ----PQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPV 837


                  ..
gi 521289059   85 IP 86
Cdd:PRK10263  838 AP 839
PRK10263 PRK10263
DNA translocase FtsK; Provisional
 17-80 8.98e-03

DNA translocase FtsK; Provisional


Pssm-ID: 236669 [Multi-domain]  Cd Length: 1355  Bit Score: 36.22  E-value: 8.98e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 521289059   17 PDFRQQMGPNPYPQMGQMGQMYQQHGQQPFTQTGGQQSYQQPGPQLFQPQPAGVQVPPMPSAQQ 80
Cdd:PRK10263  743 PLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQ 806
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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